Norman P. Higgins - Publications

Affiliations: 
Biochemistry and Molecular Genetics University of Alabama, Birmingham, Birmingham, AL, United States 
Area:
Biochemistry, Genetics, Molecular Biology

52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Rovinskiy NS, Agbleke AA, Chesnokova ON, Higgins NP. Supercoil Levels in and Chromosomes Are Regulated by the C-Terminal 35⁻38 Amino Acids of GyrA. Microorganisms. 7. PMID 30875939 DOI: 10.3390/microorganisms7030081  0.608
2016 Higgins NP. Species-specific supercoil dynamics of the bacterial nucleoid. Biophysical Reviews. 8: 113-121. PMID 28510215 DOI: 10.1007/s12551-016-0207-9  0.587
2015 Higgins NP, Vologodskii AV. Topological Behavior of Plasmid DNA. Microbiology Spectrum. 3. PMID 26104708 DOI: 10.1128/microbiolspec.PLAS-0036-2014  0.464
2014 Higgins NP. RNA polymerase: chromosome domain boundary maker and regulator of supercoil density. Current Opinion in Microbiology. 22: 138-43. PMID 25460807 DOI: 10.1016/j.mib.2014.10.002  0.533
2012 Rovinskiy N, Agbleke AA, Chesnokova O, Pang Z, Higgins NP. Rates of gyrase supercoiling and transcription elongation control supercoil density in a bacterial chromosome. Plos Genetics. 8: e1002845. PMID 22916023 DOI: 10.1371/Journal.Pgen.1002845  0.609
2010 Booker BM, Deng S, Higgins NP. DNA topology of highly transcribed operons in Salmonella enterica serovar Typhimurium. Molecular Microbiology. 78: 1348-64. PMID 21143310 DOI: 10.1111/J.1365-2958.2010.07394.X  0.725
2010 Higgins NP, Booker BM, Manna D. Molecular structure and dynamics of bacterial nucleoids Bacterial Chromatin. 117-148. DOI: 10.1007/978-90-481-3473-1-7  0.723
2007 Manna D, Porwollik S, McClelland M, Tan R, Higgins NP. Microarray analysis of Mu transposition in Salmonella enterica, serovar Typhimurium: transposon exclusion by high-density DNA binding proteins. Molecular Microbiology. 66: 315-28. PMID 17850262 DOI: 10.1111/j.1365-2958.2007.05915.x  0.55
2007 Champion K, Higgins NP. Growth rate toxicity phenotypes and homeostatic supercoil control differentiate Escherichia coli from Salmonella enterica serovar Typhimurium. Journal of Bacteriology. 189: 5839-49. PMID 17400739 DOI: 10.1128/JB.00083-07  0.512
2007 Higgins NP. Mutational bias suggests that replication termination occurs near the dif site, not at Ter sites: what's the Dif? Molecular Microbiology. 64: 1-4. PMID 17376066 DOI: 10.1111/j.1365-2958.2007.05641.x  0.352
2005 Pang Z, Chen R, Manna D, Higgins NP. A gyrase mutant with low activity disrupts supercoiling at the replication terminus. Journal of Bacteriology. 187: 7773-83. PMID 16267301 DOI: 10.1128/JB.187.22.7773-7783.2005  0.487
2005 Deng S, Stein RA, Higgins NP. Organization of supercoil domains and their reorganization by transcription. Molecular Microbiology. 57: 1511-21. PMID 16135220 DOI: 10.1111/j.1365-2958.2005.04796.x  0.583
2005 Manna D, Deng S, Breier AM, Higgins NP. Bacteriophage Mu targets the trinucleotide sequence CGG. Journal of Bacteriology. 187: 3586-8. PMID 15866949 DOI: 10.1128/Jb.187.10.3586-3588.2005  0.383
2005 Stein RA, Deng S, Higgins NP. Measuring chromosome dynamics on different time scales using resolvases with varying half-lives. Molecular Microbiology. 56: 1049-61. PMID 15853889 DOI: 10.1111/j.1365-2958.2005.04588.x  0.471
2004 Manna D, Breier AM, Higgins NP. Microarray analysis of transposition targets in Escherichia coli: the impact of transcription. Proceedings of the National Academy of Sciences of the United States of America. 101: 9780-5. PMID 15210965 DOI: 10.1073/Pnas.0400745101  0.554
2004 Deng S, Stein RA, Higgins NP. Transcription-induced barriers to supercoil diffusion in the Salmonella typhimurium chromosome. Proceedings of the National Academy of Sciences of the United States of America. 101: 3398-403. PMID 14993611 DOI: 10.1073/pnas.0307550101  0.576
2001 Manna D, Wang X, Higgins NP. Mu and IS1 transpositions exhibit strong orientation bias at the Escherichia coli bgl locus. Journal of Bacteriology. 183: 3328-35. PMID 11344140 DOI: 10.1128/JB.183.11.3328-3335.2001  0.35
2001 Scheirer KE, Higgins NP. Transcription induces a supercoil domain barrier in bacteriophage Mu. Biochimie. 83: 155-9. PMID 11278064 DOI: 10.1016/S0300-9084(00)01215-3  0.394
1999 Manna D, Higgins NP. Phage Mu transposition immunity reflects supercoil domain structure of the chromosome. Molecular Microbiology. 32: 595-606. PMID 10320581 DOI: 10.1046/j.1365-2958.1999.01377.x  0.324
1998 Staczek P, Higgins NP. Gyrase and Topo IV modulate chromosome domain size in vivo. Molecular Microbiology. 29: 1435-48. PMID 9781880 DOI: 10.1046/j.1365-2958.1998.01025.x  0.523
1997 Scheirer KE, Higgins NP. The DNA cleavage reaction of DNA gyrase. Comparison of stable ternary complexes formed with enoxacin and CcdB protein. The Journal of Biological Chemistry. 272: 27202-9. PMID 9341164 DOI: 10.1074/jbc.272.43.27202  0.4
1996 Higgins NP, Yang X, Fu Q, Roth JR. Surveying a supercoil domain by using the gamma delta resolution system in Salmonella typhimurium. Journal of Bacteriology. 178: 2825-35. PMID 8631670 DOI: 10.1128/Jb.178.10.2825-2835.1996  0.49
1995 Pawlik KM, Sun CW, Higgins NP, Townes TM. End joining of genomic DNA and transgene DNA in fertilized mouse eggs. Gene. 165: 173-81. PMID 8522172 DOI: 10.1016/0378-1119(95)00519-C  0.381
1995 Pato ML, Karlok M, Wall C, Higgins NP. Characterization of Mu prophage lacking the central strong gyrase binding site: localization of the block in replication. Journal of Bacteriology. 177: 5937-42. PMID 7592347  0.434
1994 Wang X, Higgins NP. 'Muprints' of the lac operon demonstrate physiological control over the randomness of in vivo transposition. Molecular Microbiology. 12: 665-77. PMID 7934890 DOI: 10.1111/j.1365-2958.1994.tb01054.x  0.322
1994 McGovern V, Higgins NP, Chiz RS, Jaworski A. H-NS over-expression induces an artificial stationary phase by silencing global transcription. Biochimie. 76: 1019-29. PMID 7748923 DOI: 10.1016/0300-9084(94)90026-4  0.324
1993 Falconi M, Higgins NP, Spurio R, Pon CL, Gualerzi CO. Expression of the gene encoding the major bacterial nucleotide protein H-NS is subject to transcriptional auto-repression. Molecular Microbiology. 10: 273-82. PMID 7934818 DOI: 10.1111/j.1365-2958.1993.tb01953.x  0.343
1991 Jaworski A, Higgins NP, Wells RD, Zacharias W. Topoisomerase mutants and physiological conditions control supercoiling and Z-DNA formation in vivo Journal of Biological Chemistry. 266: 2576-2581. PMID 1846630  0.475
1991 Vogel JL, Li ZJ, Howe MM, Toussaint A, Higgins NP. Temperature-sensitive mutations in the bacteriophage Mu c repressor locate a 63-amino-acid DNA-binding domain. Journal of Bacteriology. 173: 6568-77. PMID 1833382  0.406
1991 Falconi M, McGovern V, Gualerzi C, Hillyard D, Higgins NP. Mutations altering chromosomal protein H-NS induce mini-Mu transposition. The New Biologist. 3: 615-25. PMID 1655013  0.492
1990 Pato ML, Howe MM, Higgins NP. A DNA gyrase-binding site at the center of the bacteriophage Mu genome is required for efficient replicative transposition. Proceedings of the National Academy of Sciences of the United States of America. 87: 8716-20. PMID 2174162  0.397
1990 Hillyard DR, Edlund M, Hughes KT, Marsh M, Higgins NP. Subunit-specific phenotypes of Salmonella typhimurium HU mutants. Journal of Bacteriology. 172: 5402-7. PMID 2168381  0.366
1989 Higgins NP, Collier DA, Kilpatrick MW, Krause HM. Supercoiling and integration host factor change the DNA conformation and alter the flow of convergent transcription in phage Mu. The Journal of Biological Chemistry. 264: 3035-42. PMID 2644278  0.433
1988 Higgins NP, Hillyard D. Primary structure and mapping of the hupA gene of Salmonella typhimurium. Journal of Bacteriology. 170: 5751-8. PMID 3056912  0.435
1988 Youderian P, Sugiono P, Brewer KL, Higgins NP, Elliott T. Packaging specific segments of the Salmonella chromosome with locked-in Mud-P22 prophages. Genetics. 118: 581-92. PMID 2835289  0.447
1986 Akroyd JE, Clayson E, Higgins NP. Purification of the gam gene-product of bacteriophage Mu and determination of the nucleotide sequence of the gam gene. Nucleic Acids Research. 14: 6901-14. PMID 2945162 DOI: 10.1093/nar/14.17.6901  0.365
1984 Higgins NP, Olivera BM. Mu DNA replication in vitro: criteria for initiation. Molecular & General Genetics : Mgg. 194: 60-4. PMID 6328220 DOI: 10.1007/BF00383498  0.316
1984 Krause HM, Higgins NP. On the mu repressor and early DNA intermediates of transposition. Cold Spring Harbor Symposia On Quantitative Biology. 49: 827-34. PMID 6099259  0.35
1984 Higgins NP, Manlapaz-Ramos P, Olivera BM. Analysis of mu DNA replicated on cellophane discs. Advances in Experimental Medicine and Biology. 179: 63-7. PMID 6098167  0.347
1983 Higgins NP, Moncecchi D, Manlapaz-Ramos P, Olivera BM. Bacteriophage Mu DNA replication in vitro. The Journal of Biological Chemistry. 258: 4293-7. PMID 6339495  0.447
1983 Higgins NP, Manlapaz-Ramos P, Gandhi RT, Olivera BM. Bacteriophage Mu: a transposing replicon. Cell. 33: 623-8. PMID 6305516 DOI: 10.1016/0092-8674(83)90443-9  0.445
1983 Ferro AM, Higgins NP, Olivera BM. Poly(ADP-ribosylation) of a DNA topoisomerase. The Journal of Biological Chemistry. 258: 6000-3. PMID 6304023  0.359
1980 Sugino A, Higgins NP, Cozzarelli NR. DNA gyrase subunit stoichiometry and the covalent attachment of subunit A to DNA during DNA cleavage. Nucleic Acids Research. 8: 3865-74. PMID 6255421 DOI: 10.1093/Nar/8.17.3865  0.456
1980 Morrison A, Higgins NP, Cozzarelli NR. Interaction between DNA gyrase and its cleavage site on DNA Journal of Biological Chemistry. 255: 2211-2219. PMID 6243661  0.374
1980 Sugino A, Higgins NP, Cozzarelli NR. DNA gyrase subunit stoichiometry and the covalent attachment of subunit a to DNA during DNA cleavage Nucleic Acids Research. 8: 3865-3874. DOI: 10.1093/nar/8.17.3865  0.39
1979 Higgins NP, Geballe AP, Cozzarelli NR. Addition of oligonucleotides to the 5′-terminus of DNA by T4 RNA ligase Nucleic Acids Research. 6: 1013-1024. PMID 375192 DOI: 10.1093/Nar/6.3.1013  0.374
1979 Higgins NP, Cozzarelli NR. DNA-joining enzymes: a review. Methods in Enzymology. 68: 50-71. PMID 232224  0.338
1979 Peebles CL, Higgins NP, Kreuzer KN, Morrison A, Brown PO, Sugino A, Cozzarelli NR. Structure and activities of Escherichia coli DNA gyrase. Cold Spring Harbor Symposia On Quantitative Biology. 43: 41-52. PMID 225110 DOI: 10.1101/Sqb.1979.043.01.008  0.362
1978 Sugino A, Higgins NP, Brown PO, Peebles CL, Cozzarelli NR. Energy coupling in DNA gyrase and the mechanism of action of novobiocin. Proceedings of the National Academy of Sciences of the United States of America. 75: 4838-42. PMID 368801 DOI: 10.1073/Pnas.75.10.4838  0.363
1978 Higgins NP, Peebles CL, Sugino A, Cozzarelli NR. Purification of subunits of Escherichia coli DNA gyrase and reconstitution of enzymatic activity. Proceedings of the National Academy of Sciences of the United States of America. 75: 1773-7. PMID 347446 DOI: 10.1073/Pnas.75.4.1773  0.376
1977 Karran P, Higgins NP, Strauss B. Intermediates in excision repair by human cells: use of S1 nuclease and benzoylated naphthoylated cellulose to reveal single-strand breaks. Biochemistry. 16: 4483-90. PMID 911770  0.359
1977 Strauss BS, Karran P, Higgins NP. Alkylation damage and DNA excision repair in mammalian cells. Journal of Toxicology and Environmental Health. 2: 1395-414. PMID 18613 DOI: 10.1080/15287397709529539  0.344
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