Rakesh C. Kukreja - Publications

Affiliations: 
Biochemistry Virginia Commonwealth University, Richmond, VA, United States 
Area:
Biochemistry

181 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Samidurai A, Olex AL, Ockaili R, Kraskauskas D, Roh SK, Kukreja RC, Das A. Integrated Analysis of lncRNA-miRNA-mRNA Regulatory Network in Rapamycin-Induced Cardioprotection against Ischemia/Reperfusion Injury in Diabetic Rabbits. Cells. 12. PMID 38132140 DOI: 10.3390/cells12242820  0.684
2023 Samidurai A, Saravanan M, Ockaili R, Kraskauskas D, Lau SYV, Kodali V, Ramasamy S, Bhoopathi K, Nair M, Roh SK, Kukreja RC, Das A. Single-Dose Treatment with Rapamycin Preserves Post-Ischemic Cardiac Function through Attenuation of Fibrosis and Inflammation in Diabetic Rabbit. International Journal of Molecular Sciences. 24. PMID 37240345 DOI: 10.3390/ijms24108998  0.772
2021 Samidurai A, Ockaili R, Cain C, Roh SK, Filippone SM, Kraskauskas D, Kukreja RC, Das A. Preclinical model of type 1 diabetes and myocardial ischemia/reperfusion injury in conscious rabbits-demonstration of cardioprotection with rapamycin. Star Protocols. 2: 100772. PMID 34485939 DOI: 10.1016/j.xpro.2021.100772  0.745
2020 Samidurai A, Ockaili R, Cain C, Roh SK, Filippone SM, Kraskauskas D, Kukreja RC, Das A. Differential Regulation of mTOR Complexes with miR-302a Attenuates Myocardial Reperfusion Injury in Diabetes. Iscience. 23: 101863. PMID 33319180 DOI: 10.1016/j.isci.2020.101863  0.747
2020 Samidurai A, Xi L, Salloum FN, Das A, Kukreja RC. PDE5 inhibitor sildenafil attenuates cardiac microRNA 214 upregulation and pro-apoptotic signaling after chronic alcohol ingestion in mice. Molecular and Cellular Biochemistry. PMID 32535704 DOI: 10.1007/S11010-020-03779-7  0.307
2020 Koka S, Xi L, Kukreja RC. Chronic inhibition of phosphodiesterase 5 with tadalafil affords cardioprotection in a mouse model of metabolic syndrome: role of nitric oxide. Molecular and Cellular Biochemistry. PMID 32162053 DOI: 10.1007/S11010-020-03710-0  0.476
2020 Bhat OM, Li G, Yuan X, Huang D, Gulbins E, Kukreja RC, Li PL. Arterial Medial Calcification through Enhanced small Extracellular Vesicle Release in Smooth Muscle-Specific Asah1 Gene Knockout Mice. Scientific Reports. 10: 1645. PMID 32015399 DOI: 10.1038/S41598-020-58568-5  0.302
2019 Samidurai A, Roh SK, Prakash M, Durrant D, Salloum FN, Kukreja RC, Das A. STAT3-miR-17/20 Signaling Axis Plays a Critical Role in Attenuating Myocardial Infarction following Rapamycin Treatment in Diabetic mice. Cardiovascular Research. PMID 31738412 DOI: 10.1093/Cvr/Cvz315  0.466
2019 Samidurai A, Roh SK, Kukreja RC, Salloum FN, Das A. Abstract 486: Deficiency of Myocardial miR-17-92 Cluster Exacerbates Ischemic Injury in Diabetic Mice Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.486  0.342
2018 Samidurai A, Kukreja RC, Das A. Emerging Role of mTOR Signaling-Related miRNAs in Cardiovascular Diseases. Oxidative Medicine and Cellular Longevity. 2018: 6141902. PMID 30305865 DOI: 10.1155/2018/6141902  0.321
2018 Viczenczova C, Kura B, Egan Benova T, Yin C, Kukreja RC, Slezak J, Tribulova N, Szeiffova Bacova B. Irradiation-Induced Cardiac Connexin-43 and miR-21 Responses Are Hampered by Treatment with Atorvastatin and Aspirin. International Journal of Molecular Sciences. 19. PMID 29642568 DOI: 10.3390/Ijms19041128  0.333
2017 Samidurai A, Salloum FN, Durrant D, Chernova OB, Kukreja RC, Das A. Chronic treatment with novel nanoformulated micelles of rapamycin, Rapatar, protects diabetic heart against ischemia/reperfusion injury. British Journal of Pharmacology. PMID 28967097 DOI: 10.1111/Bph.14059  0.455
2017 Slezak J, Kura B, Babal P, Barancik M, Ferko M, Frimmel K, Kalocayova B, Kukreja RC, Lazou A, Mezesova L, Okruhlicova L, Ravingerova T, Singal PK, Szeiffova Bacova B, Viczenczova C, et al. Potential markers and metabolic processes involved in the mechanism of radiation-induced heart injury. Canadian Journal of Physiology and Pharmacology. 1-14. PMID 28750189 DOI: 10.1139/Cjpp-2017-0121  0.371
2017 Tur J, Badole SL, Cheng F, Das A, Kukreja RC, Tipparaju SM. Corticosteroids and aldose reductase inhibitor Epalrestat modulates cardiac action potential via Kvβ1.1 (AKR6A8) subunit of voltage-gated potassium channel. Molecular and Cellular Biochemistry. PMID 28585087 DOI: 10.1007/S11010-017-3079-9  0.352
2017 Filippone SM, Samidurai A, Roh SK, Cain CK, He J, Salloum FN, Kukreja RC, Das A. Reperfusion Therapy with Rapamycin Attenuates Myocardial Infarction through Activation of AKT and ERK. Oxidative Medicine and Cellular Longevity. 2017: 4619720. PMID 28373901 DOI: 10.1155/2017/4619720  0.529
2017 Nagiub M, Filippone S, Durrant D, Das A, Kukreja RC. Long-acting PDE5 inhibitor tadalafil prevents early doxorubicin-induced left ventricle diastolic dysfunction in juvenile mice: potential role of cytoskeletal proteins. Canadian Journal of Physiology and Pharmacology. 1-10. PMID 28238269 DOI: 10.1139/Cjpp-2016-0551  0.417
2017 Kukreja RC. The Swiss army knife for the heart: Kvβ1.1 a multifunctional tool. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00005.2017. PMID 28130332 DOI: 10.1152/Ajpheart.00005.2017  0.315
2017 Wang R, Xi L, Kukreja RC. PDE5 Inhibitor Tadalafil and Hydroxychloroquine Co-Treatment Provides Synergistic Protection against Type 2 Diabetes and Myocardial Infarction in Mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 28123046 DOI: 10.1124/Jpet.116.239087  0.455
2016 Das A, Kukreja RC. Role of mTOR Signaling in Cardioprotection Molecules to Medicine With Mtor: Translating Critical Pathways Into Novel Therapeutic Strategies. 245-262. DOI: 10.1016/B978-0-12-802733-2.00003-7  0.346
2015 Das A, Durrant D, Mitchell C, Dent P, Batra SK, Kukreja RC. Sildenafil (Viagra) sensitizes prostate cancer cells to doxorubicin-mediated apoptosis through CD95. Oncotarget. PMID 26716643 DOI: 10.18632/Oncotarget.6749  0.309
2015 Durrant DE, Das A, Dyer S, Tavallai S, Dent P, Kukreja RC. Targeted Inhibition of Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Sensitizes Pancreatic Cancer Cells to Doxorubicin without Exacerbating Cardiac Toxicity. Molecular Pharmacology. 88: 512-23. PMID 26101222 DOI: 10.1124/Mol.115.099143  0.359
2015 Das A, Samidurai A, Hoke NN, Kukreja RC, Salloum FN. Hydrogen sulfide mediates the cardioprotective effects of gene therapy with PKG-Iα. Basic Research in Cardiology. 110: 42. PMID 26036467 DOI: 10.1007/S00395-015-0500-Y  0.781
2015 Das A, Salloum FN, Filippone SM, Durrant DE, Rokosh G, Bolli R, Kukreja RC. Inhibition of mammalian target of rapamycin protects against reperfusion injury in diabetic heart through STAT3 signaling. Basic Research in Cardiology. 110: 31. PMID 25911189 DOI: 10.1007/S00395-015-0486-5  0.46
2015 Gill R, Kuriakose R, Gertz ZM, Salloum FN, Xi L, Kukreja RC. Remote ischemic preconditioning for myocardial protection: update on mechanisms and clinical relevance. Molecular and Cellular Biochemistry. 402: 41-9. PMID 25552250 DOI: 10.1007/S11010-014-2312-Z  0.452
2015 Jones SP, Tang XL, Guo Y, Steenbergen C, Lefer DJ, Kukreja RC, Kong M, Li Q, Bhushan S, Zhu X, Du J, Nong Y, Stowers HL, Kondo K, Hunt GN, et al. The NHLBI-sponsored Consortium for preclinicAl assESsment of cARdioprotective therapies (CAESAR): a new paradigm for rigorous, accurate, and reproducible evaluation of putative infarct-sparing interventions in mice, rabbits, and pigs. Circulation Research. 116: 572-86. PMID 25499773 DOI: 10.1161/Circresaha.116.305462  0.744
2015 Das A, Durrant D, Salloum FN, Xi L, Kukreja RC. PDE5 inhibitors as therapeutics for heart disease, diabetes and cancer. Pharmacology & Therapeutics. 147: 12-21. PMID 25444755 DOI: 10.1016/J.Pharmthera.2014.10.003  0.44
2015 Salloum FN, Sturz GR, Yin C, Rehman S, Hoke NN, Kukreja RC, Xi L. Beetroot juice reduces infarct size and improves cardiac function following ischemia-reperfusion injury: Possible involvement of endogenous H2S. Experimental Biology and Medicine (Maywood, N.J.). 240: 669-81. PMID 25361774 DOI: 10.1177/1535370214558024  0.801
2015 Kositprapa C, Topaz O, Samidurai A, Okubo S, Kasirajan V, Kukreja RC. Preconditioning of the heart following transmyocardial revascularization Lasers in Cardiovascular Interventions. 305-310. DOI: 10.1007/978-1-4471-5220-0_22  0.409
2014 Salloum FN, Chau VQ, Hoke NN, Kukreja RC. Tadalafil prevents acute heart failure with reduced ejection fraction in mice. Cardiovascular Drugs and Therapy / Sponsored by the International Society of Cardiovascular Pharmacotherapy. 28: 493-500. PMID 25322707 DOI: 10.1007/S10557-014-6559-0  0.732
2014 Toldo S, Das A, Mezzaroma E, Chau VQ, Marchetti C, Durrant D, Samidurai A, Van Tassell BW, Yin C, Ockaili RA, Vigneshwar N, Mukhopadhyay ND, Kukreja RC, Abbate A, Salloum FN. Induction of microRNA-21 with exogenous hydrogen sulfide attenuates myocardial ischemic and inflammatory injury in mice. Circulation. Cardiovascular Genetics. 7: 311-20. PMID 24825878 DOI: 10.1161/Circgenetics.113.000381  0.752
2014 Koka S, Aluri HS, Xi L, Lesnefsky EJ, Kukreja RC. Chronic inhibition of phosphodiesterase 5 with tadalafil attenuates mitochondrial dysfunction in type 2 diabetic hearts: potential role of NO/SIRT1/PGC-1α signaling. American Journal of Physiology. Heart and Circulatory Physiology. 306: H1558-68. PMID 24727492 DOI: 10.1152/Ajpheart.00865.2013  0.386
2014 Roberts JL, Booth L, Conley A, Cruickshanks N, Malkin M, Kukreja RC, Grant S, Poklepovic A, Dent P. PDE5 inhibitors enhance the lethality of standard of care chemotherapy in pediatric CNS tumor cells. Cancer Biology & Therapy. 15: 758-67. PMID 24651037 DOI: 10.4161/Cbt.28553  0.305
2014 Shalwala M, Zhu SG, Das A, Salloum FN, Xi L, Kukreja RC. Sirtuin 1 (SIRT1) activation mediates sildenafil induced delayed cardioprotection against ischemia-reperfusion injury in mice. Plos One. 9: e86977. PMID 24466304 DOI: 10.1371/Journal.Pone.0086977  0.446
2014 Das A, Durrant D, Koka S, Salloum FN, Xi L, Kukreja RC. Mammalian target of rapamycin (mTOR) inhibition with rapamycin improves cardiac function in type 2 diabetic mice: potential role of attenuated oxidative stress and altered contractile protein expression. The Journal of Biological Chemistry. 289: 4145-60. PMID 24371138 DOI: 10.1074/Jbc.M113.521062  0.412
2014 Booth L, Roberts JL, Cruickshanks N, Conley A, Durrant DE, Das A, Fisher PB, Kukreja RC, Grant S, Poklepovic A, Dent P. Phosphodiesterase 5 inhibitors enhance chemotherapy killing in gastrointestinal/genitourinary cancer cells. Molecular Pharmacology. 85: 408-19. PMID 24353313 DOI: 10.1124/Mol.113.090043  0.304
2014 Viczenczova C, Bacova B, Benova T, Kura B, Yin C, Kukreja R, Slezak J, Tribulova N. P571Irradiation of thorax triggers signaling with potential acute cardioprotective benefits in rats Cardiovascular Research. 103: S102.3-S103. DOI: 10.1093/Cvr/Cvu098.3  0.38
2014 Kura B, Viczenczova C, Frimmel K, Ravingerova T, Tribulova N, Okruhlicova L, Lazou A, Kukreja R, Fulop M, Slezak J. P688The effect of ionizing radiation on morphological and molecular changes of the rat myocardium Cardiovascular Research. 103: S126.1-S126. DOI: 10.1093/Cvr/Cvu098.112  0.344
2014 Slezak J, Barancik M, Ravingerova T, Kura B, Lazou A, Kukreja R, Fulop M, Vinczencyova C, Okruhlicova L. P131Mechanisms involved in early phase of cardiovascular response after mediastinal region irradiation Cardiovascular Research. 103: S23.2-S23. DOI: 10.1093/Cvr/Cvu082.71  0.39
2013 Kukreja RC. Sildenafil and cardioprotection. Current Pharmaceutical Design. 19: 6842-7. PMID 23590161 DOI: 10.2174/138161281939131127110156  0.463
2013 Chiplunkar AR, Lung TK, Alhashem Y, Koppenhaver BA, Salloum FN, Kukreja RC, Haar JL, Lloyd JA. Krüppel-like factor 2 is required for normal mouse cardiac development. Plos One. 8: e54891. PMID 23457456 DOI: 10.1371/Journal.Pone.0054891  0.34
2013 Koka S, Das A, Salloum FN, Kukreja RC. Phosphodiesterase-5 inhibitor tadalafil attenuates oxidative stress and protects against myocardial ischemia/reperfusion injury in type 2 diabetic mice. Free Radical Biology & Medicine. 60: 80-8. PMID 23385031 DOI: 10.1016/J.Freeradbiomed.2013.01.031  0.468
2012 Varma A, Das A, Hoke NN, Durrant DE, Salloum FN, Kukreja RC. Anti-inflammatory and cardioprotective effects of tadalafil in diabetic mice. Plos One. 7: e45243. PMID 23028874 DOI: 10.1371/Journal.Pone.0045243  0.722
2012 Das A, Salloum FN, Durrant D, Ockaili R, Kukreja RC. Rapamycin protects against myocardial ischemia-reperfusion injury through JAK2-STAT3 signaling pathway. Journal of Molecular and Cellular Cardiology. 53: 858-69. PMID 22999860 DOI: 10.1016/J.Yjmcc.2012.09.007  0.796
2012 Kukreja RC. Phosphodiesterase-5 and retargeting of subcellular cGMP signaling during pathological hypertrophy. Circulation. 126: 916-9. PMID 22829022 DOI: 10.1161/Circulationaha.112.124966  0.31
2012 Kukreja RC, Salloum FN, Das A. Cyclic guanosine monophosphate signaling and phosphodiesterase-5 inhibitors in cardioprotection. Journal of the American College of Cardiology. 59: 1921-7. PMID 22624832 DOI: 10.1016/J.Jacc.2011.09.086  0.452
2012 Xi L, Zhu SG, Das A, Chen Q, Durrant D, Hobbs DC, Lesnefsky EJ, Kukreja RC. Dietary inorganic nitrate alleviates doxorubicin cardiotoxicity: mechanisms and implications. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 26: 274-84. PMID 22484629 DOI: 10.1016/J.Niox.2012.03.006  0.403
2012 Koka S, Xi L, Kukreja RC. Chronic treatment with long acting phosphodiesterase-5 inhibitor tadalafil alters proteomic changes associated with cytoskeletal rearrangement and redox regulation in Type 2 diabetic hearts. Basic Research in Cardiology. 107: 249. PMID 22311732 DOI: 10.1007/S00395-012-0249-5  0.372
2012 Salloum FN, Das A, Samidurai A, Hoke NN, Chau VQ, Ockaili RA, Stasch JP, Kukreja RC. Cinaciguat, a novel activator of soluble guanylate cyclase, protects against ischemia/reperfusion injury: role of hydrogen sulfide. American Journal of Physiology. Heart and Circulatory Physiology. 302: H1347-54. PMID 22268103 DOI: 10.1152/Ajpheart.00544.2011  0.831
2012 Hoke NN, Salloum FN, Kass DA, Das A, Kukreja RC. Preconditioning by phosphodiesterase-5 inhibition improves therapeutic efficacy of adipose-derived stem cells following myocardial infarction in mice. Stem Cells (Dayton, Ohio). 30: 326-35. PMID 22102597 DOI: 10.1002/Stem.789  0.753
2012 Zhu SG, Xi L, Kukreja RC. Type 2 diabetic obese db/db mice are refractory to myocardial ischaemic post-conditioning in vivo: potential role for Hsp20, F1-ATPase δ and Echs1. Journal of Cellular and Molecular Medicine. 16: 950-8. PMID 21722304 DOI: 10.1111/J.1582-4934.2011.01376.X  0.424
2012 Aluri HS, Koka SS, Lesnefsky EJ, Kukreja RC. Chronic treatment with the long acting phosphodiesterase-5 inhibitor, tadalafil, decreases mitochondrial damage in diabetic mice Mitochondrion. 12: 576. DOI: 10.1016/J.Mito.2012.07.067  0.306
2011 Kukreja RC, Salloum FN, Das A, Koka S, Ockaili RA, Xi L. Emerging new uses of phosphodiesterase-5 inhibitors in cardiovascular diseases. Experimental and Clinical Cardiology. 16: e30-5. PMID 22131856  0.743
2011 Szczepanek K, Chen Q, Derecka M, Salloum FN, Zhang Q, Szelag M, Cichy J, Kukreja RC, Dulak J, Lesnefsky EJ, Larner AC. Mitochondrial-targeted Signal transducer and activator of transcription 3 (STAT3) protects against ischemia-induced changes in the electron transport chain and the generation of reactive oxygen species. The Journal of Biological Chemistry. 286: 29610-20. PMID 21715323 DOI: 10.1074/Jbc.M111.226209  0.368
2011 Movsesian MA, Kukreja RC. Phosphodiesterase inhibition in heart failure. Handbook of Experimental Pharmacology. 237-49. PMID 21695643 DOI: 10.1007/978-3-642-17969-3_10  0.41
2011 Zhu SG, Kukreja RC, Das A, Chen Q, Lesnefsky EJ, Xi L. Dietary nitrate supplementation protects against Doxorubicin-induced cardiomyopathy by improving mitochondrial function. Journal of the American College of Cardiology. 57: 2181-9. PMID 21596234 DOI: 10.1016/J.Jacc.2011.01.024  0.321
2011 Huizar JF, Kaszala K, Potfay J, Minisi AJ, Lesnefsky EJ, Abbate A, Mezzaroma E, Chen Q, Kukreja RC, Hoke NN, Thacker LR, Ellenbogen KA, Wood MA. Left ventricular systolic dysfunction induced by ventricular ectopy: a novel model for premature ventricular contraction-induced cardiomyopathy. Circulation. Arrhythmia and Electrophysiology. 4: 543-9. PMID 21576277 DOI: 10.1161/Circep.111.962381  0.728
2011 Chau VQ, Salloum FN, Hoke NN, Abbate A, Kukreja RC. Mitigation of the progression of heart failure with sildenafil involves inhibition of RhoA/Rho-kinase pathway. American Journal of Physiology. Heart and Circulatory Physiology. 300: H2272-9. PMID 21398594 DOI: 10.1152/Ajpheart.00654.2010  0.752
2011 Xi L, Zhu SG, Hobbs DC, Kukreja RC. Identification of protein targets underlying dietary nitrate-induced protection against doxorubicin cardiotoxicity. Journal of Cellular and Molecular Medicine. 15: 2512-24. PMID 21251210 DOI: 10.1111/J.1582-4934.2011.01257.X  0.361
2010 Koka S, Kukreja RC. Attenuation of Doxorubicin-induced Cardiotoxicity by Tadalafil: A Long Acting Phosphodiesterase-5 Inhibitor. Molecular and Cellular Pharmacology. 2: 173-178. PMID 21499570 DOI: 10.4255/mcpharmacol.10.23  0.377
2010 Salloum FN, Yin C, Kukreja RC. Role of microRNAs in cardiac preconditioning. Journal of Cardiovascular Pharmacology. 56: 581-8. PMID 20980922 DOI: 10.1097/Fjc.0B013E3181F581Ba  0.313
2010 Das A, Durrant D, Mitchell C, Mayton E, Hoke NN, Salloum FN, Park MA, Qureshi I, Lee R, Dent P, Kukreja RC. Sildenafil increases chemotherapeutic efficacy of doxorubicin in prostate cancer and ameliorates cardiac dysfunction. Proceedings of the National Academy of Sciences of the United States of America. 107: 18202-7. PMID 20884855 DOI: 10.1073/Pnas.1006965107  0.792
2010 Ghosh SS, Salloum FN, Abbate A, Krieg R, Sica DA, Gehr TW, Kukreja RC. Curcumin prevents cardiac remodeling secondary to chronic renal failure through deactivation of hypertrophic signaling in rats. American Journal of Physiology. Heart and Circulatory Physiology. 299: H975-84. PMID 20601462 DOI: 10.1152/Ajpheart.00154.2010  0.344
2010 Koka S, Das A, Zhu SG, Durrant D, Xi L, Kukreja RC. Long-acting phosphodiesterase-5 inhibitor tadalafil attenuates doxorubicin-induced cardiomyopathy without interfering with chemotherapeutic effect. The Journal of Pharmacology and Experimental Therapeutics. 334: 1023-30. PMID 20543097 DOI: 10.1124/Jpet.110.170191  0.464
2009 Salloum FN, Chau VQ, Hoke NN, Abbate A, Varma A, Ockaili RA, Toldo S, Kukreja RC. Phosphodiesterase-5 inhibitor, tadalafil, protects against myocardial ischemia/reperfusion through protein-kinase g-dependent generation of hydrogen sulfide. Circulation. 120: S31-6. PMID 19752383 DOI: 10.1161/Circulationaha.108.843979  0.815
2009 Hoke NN, Salloum FN, Loesser-Casey KE, Kukreja RC. Cardiac regenerative potential of adipose tissue-derived stem cells. Acta Physiologica Hungarica. 96: 251-65. PMID 19706369 DOI: 10.1556/Aphysiol.96.2009.3.1  0.723
2009 Vandeput F, Krall J, Ockaili R, Salloum FN, Florio V, Corbin JD, Francis SH, Kukreja RC, Movsesian MA. cGMP-hydrolytic activity and its inhibition by sildenafil in normal and failing human and mouse myocardium. The Journal of Pharmacology and Experimental Therapeutics. 330: 884-91. PMID 19546307 DOI: 10.1124/Jpet.109.154468  0.751
2009 Das A, Salloum FN, Xi L, Rao YJ, Kukreja RC. ERK phosphorylation mediates sildenafil-induced myocardial protection against ischemia-reperfusion injury in mice. American Journal of Physiology. Heart and Circulatory Physiology. 296: H1236-43. PMID 19286961 DOI: 10.1152/Ajpheart.00100.2009  0.48
2009 Yin C, Salloum FN, Kukreja RC. A novel role of microRNA in late preconditioning: upregulation of endothelial nitric oxide synthase and heat shock protein 70. Circulation Research. 104: 572-5. PMID 19213952 DOI: 10.1161/Circresaha.108.193250  0.317
2009 Kukreja RC, Chau VQ, Hoke NN, Abbate A, Varma A, Ockaili RA, Toldo S, Salloum FN. Phosphodiesterase-5 inhibition and cardioprotection: Potential role of hydrogen sulfide Bmc Pharmacology. 9. DOI: 10.1186/1471-2210-9-S1-S24  0.761
2008 Yin C, Wang X, Kukreja RC. Endogenous microRNAs induced by heat-shock reduce myocardial infarction following ischemia-reperfusion in mice. Febs Letters. 582: 4137-42. PMID 19041309 DOI: 10.1016/J.Febslet.2008.11.014  0.361
2008 Xi L, Das A, Zhao ZQ, Merino VF, Bader M, Kukreja RC. Loss of myocardial ischemic postconditioning in adenosine A1 and bradykinin B2 receptors gene knockout mice. Circulation. 118: S32-7. PMID 18824766 DOI: 10.1161/Circulationaha.107.752865  0.353
2008 Abbate A, Bussani R, Sinagra G, Barresi E, Pivetta A, Perkan A, Hoke NH, Salloum FN, Kontos MC, Biondi-Zoccai GG, Vetrovec GW, Sabbadini G, Baldi F, Silvestri F, Kukreja RC, et al. Right ventricular cardiomyocyte apoptosis in patients with acute myocardial infarction of the left ventricular wall. The American Journal of Cardiology. 102: 658-62. PMID 18773983 DOI: 10.1016/J.Amjcard.2008.05.007  0.435
2008 Das A, Xi L, Kukreja RC. Protein kinase G-dependent cardioprotective mechanism of phosphodiesterase-5 inhibition involves phosphorylation of ERK and GSK3beta. The Journal of Biological Chemistry. 283: 29572-85. PMID 18723505 DOI: 10.1074/Jbc.M801547200  0.495
2008 Abbate A, Salloum FN, Vecile E, Das A, Hoke NN, Straino S, Biondi-Zoccai GG, Houser JE, Qureshi IZ, Ownby ED, Gustini E, Biasucci LM, Severino A, Capogrossi MC, Vetrovec GW, ... ... Kukreja RC, et al. Anakinra, a recombinant human interleukin-1 receptor antagonist, inhibits apoptosis in experimental acute myocardial infarction. Circulation. 117: 2670-83. PMID 18474815 DOI: 10.1161/Circulationaha.107.740233  0.79
2008 Natarajan R, Salloum FN, Fisher BJ, Kukreja RC, Fowler AA. Hypoxia inducible factor-1 upregulates adiponectin in diabetic mouse hearts and attenuates post-ischemic injury. Journal of Cardiovascular Pharmacology. 51: 178-87. PMID 18287886 DOI: 10.1097/Fjc.0B013E31815F248D  0.411
2008 Salloum FN, Abbate A, Das A, Houser JE, Mudrick CA, Qureshi IZ, Hoke NN, Roy SK, Brown WR, Prabhakar S, Kukreja RC. Sildenafil (Viagra) attenuates ischemic cardiomyopathy and improves left ventricular function in mice. American Journal of Physiology. Heart and Circulatory Physiology. 294: H1398-406. PMID 18223185 DOI: 10.1152/Ajpheart.Ajpheart.91438.2007  0.824
2008 Wang X, Fisher PW, Xi L, Kukreja RC. Essential role of mitochondrial Ca2+-activated and ATP-sensitive K+ channels in sildenafil-induced late cardioprotection. Journal of Molecular and Cellular Cardiology. 44: 105-13. PMID 18021798 DOI: 10.1016/J.Yjmcc.2007.10.006  0.362
2008 Singh RB, Dudova D, Pella D, Gupta SB, Kukreja RC. Effects of sildenafil in cardiovascular disease World Heart Journal. 1: 79-84.  0.33
2007 Straino S, Salloum FN, Baldi A, Ockaili RA, Piro M, Das A, Qureshi IZ, Biasucci LM, Capogrossi MC, Biondi-Zoccai GG, Severino A, Mellone P, Crea F, Vetrovec GW, Kukreja RC, et al. Protective effects of parecoxib, a cyclo-oxygenase-2 inhibitor, in postinfarction remodeling in the rat. Journal of Cardiovascular Pharmacology. 50: 571-7. PMID 18030068 DOI: 10.1097/Fjc.0B013E31814B91Cb  0.796
2007 Salloum FN, Das A, Thomas CS, Yin C, Kukreja RC. Adenosine A(1) receptor mediates delayed cardioprotective effect of sildenafil in mouse. Journal of Molecular and Cellular Cardiology. 43: 545-51. PMID 17920622 DOI: 10.1016/J.Yjmcc.2007.08.014  0.513
2007 Abbate A, Salloum FN, Ockaili RA, Fowler AA, Biondi-Zoccai GG, Straino S, Lipinski MJ, Baldi A, Crea F, Biasucci LM, Vetrovec GW, Kukreja RC. Improvement of cardiac function with parecoxib, a cyclo-oxygenase-2 inhibitor, in a rat model of ischemic heart failure. Journal of Cardiovascular Pharmacology. 49: 416-8. PMID 17577107 DOI: 10.1097/Fjc.0B013E31804A5E50  0.747
2007 Natarajan R, Salloum FN, Fisher BJ, Ownby ED, Kukreja RC, Fowler AA. Activation of hypoxia-inducible factor-1 via prolyl-4 hydoxylase-2 gene silencing attenuates acute inflammatory responses in postischemic myocardium. American Journal of Physiology. Heart and Circulatory Physiology. 293: H1571-80. PMID 17545479 DOI: 10.1152/Ajpheart.00291.2007  0.456
2007 Kukreja RC. Cardiovascular protection with sildenafil following chronic inhibition of nitric oxide synthase British Journal of Pharmacology. 150: 538-540. PMID 17245364 DOI: 10.1038/Sj.Bjp.0707132  0.467
2007 Kukreja RC, Xi L. eNOS phosphorylation: a pivotal molecular switch in vasodilation and cardioprotection? Journal of Molecular and Cellular Cardiology. 42: 280-2. PMID 17174975 DOI: 10.1016/J.Yjmcc.2006.10.011  0.36
2007 Salloum FN, Takenoshita Y, Ockaili RA, Daoud VP, Chou E, Yoshida K, Kukreja RC. Sildenafil and vardenafil but not nitroglycerin limit myocardial infarction through opening of mitochondrial K(ATP) channels when administered at reperfusion following ischemia in rabbits. Journal of Molecular and Cellular Cardiology. 42: 453-8. PMID 17157308 DOI: 10.1016/J.Yjmcc.2006.10.015  0.769
2007 Kukreja R, Salloum F, Xi L. Anti-ischemic effects of sildenafil, vardenafil and tadalafil in heart. International Journal of Impotence Research. 19: 226-7. PMID 17136101 DOI: 10.1038/Sj.Ijir.3901533  0.381
2007 Kukreja RC, Salloum FN, Xi L. Nonurologic applications of phosphodiesterase type 5 inhibitors Current Sexual Health Reports. 4: 64-70. DOI: 10.1007/S11930-007-0004-3  0.43
2006 Das A, Smolenski A, Lohmann SM, Kukreja RC. Cyclic GMP-dependent protein kinase Ialpha attenuates necrosis and apoptosis following ischemia/reoxygenation in adult cardiomyocyte. The Journal of Biological Chemistry. 281: 38644-52. PMID 17038326 DOI: 10.1074/Jbc.M606142200  0.435
2006 Kukreja RC. Mechanism of reactive oxygen species generation after opening of mitochondrial KATP channels. American Journal of Physiology. Heart and Circulatory Physiology. 291: H2041-3. PMID 16877554 DOI: 10.1152/Ajpheart.00772.2006  0.325
2006 Khan S, Salloum F, Das A, Xi L, Vetrovec GW, Kukreja RC. Rapamycin confers preconditioning-like protection against ischemia-reperfusion injury in isolated mouse heart and cardiomyocytes. Journal of Molecular and Cellular Cardiology. 41: 256-64. PMID 16769083 DOI: 10.1016/J.Yjmcc.2006.04.014  0.562
2006 Xi L, Ghosh S, Wang X, Das A, Anderson FP, Kukreja RC. Hypercholesterolemia enhances tolerance to lethal systemic hypoxia in middle-aged mice: possible role of VEGF downregulation in brain. Molecular and Cellular Biochemistry. 291: 205-11. PMID 16718361 DOI: 10.1007/S11010-006-9194-7  0.325
2006 Kukreja RC. Synergistic effects of atorvastatin and sildenafil in cardioprotection--role of NO. Cardiovascular Drugs and Therapy / Sponsored by the International Society of Cardiovascular Pharmacotherapy. 20: 5-8. PMID 16534545 DOI: 10.1007/S10557-006-7298-7  0.537
2006 Salloum FN, Ockaili RA, Wittkamp M, Marwaha VR, Kukreja RC. Vardenafil: a novel type 5 phosphodiesterase inhibitor reduces myocardial infarct size following ischemia/reperfusion injury via opening of mitochondrial K(ATP) channels in rabbits. Journal of Molecular and Cellular Cardiology. 40: 405-11. PMID 16480739 DOI: 10.1016/J.Yjmcc.2005.10.002  0.787
2006 Tekin D, Xi L, Kukreja RC. Genetic deletion of fas receptors or Fas ligands does not reduce infarct size after acute global ischemia-reperfusion in isolated mouse heart. Cell Biochemistry and Biophysics. 44: 111-7. PMID 16456239 DOI: 10.1385/Cbb:44:1:111  0.481
2006 Natarajan R, Salloum FN, Fisher BJ, Kukreja RC, Fowler AA. Hypoxia inducible factor-1 activation by prolyl 4-hydroxylase-2 gene silencing attenuates myocardial ischemia reperfusion injury. Circulation Research. 98: 133-40. PMID 16306444 DOI: 10.1161/01.Res.0000197816.63513.27  0.439
2005 Yin C, Xi L, Wang X, Eapen M, Kukreja RC. Silencing heat shock factor 1 by small interfering RNA abrogates heat shock-induced cardioprotection against ischemia-reperfusion injury in mice. Journal of Molecular and Cellular Cardiology. 39: 681-9. PMID 16125197 DOI: 10.1016/J.Yjmcc.2005.06.005  0.453
2005 Kukreja RC, Salloum F, Das A, Ockaili R, Yin C, Bremer YA, Fisher PW, Wittkamp M, Hawkins J, Chou E, Kukreja AK, Wang X, Marwaha VR, Xi L. Pharmacological preconditioning with sildenafil: Basic mechanisms and clinical implications. Vascular Pharmacology. 42: 219-32. PMID 15922255 DOI: 10.1016/J.Vph.2005.02.010  0.765
2005 Fisher PW, Salloum F, Das A, Hyder H, Kukreja RC. Phosphodiesterase-5 inhibition with sildenafil attenuates cardiomyocyte apoptosis and left ventricular dysfunction in a chronic model of doxorubicin cardiotoxicity. Circulation. 111: 1601-10. PMID 15811867 DOI: 10.1161/01.Cir.0000160359.49478.C2  0.47
2005 Ockaili R, Natarajan R, Salloum F, Fisher BJ, Jones D, Fowler AA, Kukreja RC. HIF-1 activation attenuates postischemic myocardial injury: role for heme oxygenase-1 in modulating microvascular chemokine generation. American Journal of Physiology. Heart and Circulatory Physiology. 289: H542-8. PMID 15805230 DOI: 10.1152/Ajpheart.00089.2005  0.77
2005 Das A, Xi L, Kukreja RC. Phosphodiesterase-5 inhibitor sildenafil preconditions adult cardiac myocytes against necrosis and apoptosis. Essential role of nitric oxide signaling. The Journal of Biological Chemistry. 280: 12944-55. PMID 15668244 DOI: 10.1074/Jbc.M404706200  0.419
2005 Bremer YA, Salloum F, Ockaili R, Chou E, Moskowitz WB, Kukreja RC. Sildenafil citrate (viagra) induces cardioprotective effects after ischemia/reperfusion injury in infant rabbits. Pediatric Research. 57: 22-7. PMID 15531735 DOI: 10.1203/01.Pdr.0000147736.27672.15  0.769
2004 Xi L, Taher M, Yin C, Salloum F, Kukreja RC. Cobalt chloride induces delayed cardiac preconditioning in mice through selective activation of HIF-1alpha and AP-1 and iNOS signaling. American Journal of Physiology. Heart and Circulatory Physiology. 287: H2369-75. PMID 15284066 DOI: 10.1152/Ajpheart.00422.2004  0.457
2004 Okubo S, Tanabe Y, Takeda K, Kitayama M, Kanemitsu S, Kukreja RC, Takekoshi N. Ischemic preconditioning and morphine attenuate myocardial apoptosis and infarction after ischemia-reperfusion in rabbits: role of delta-opioid receptor. American Journal of Physiology. Heart and Circulatory Physiology. 287: H1786-91. PMID 15231506 DOI: 10.1152/Ajpheart.01143.2003  0.45
2004 Wang X, Yin C, Xi L, Kukreja RC. Opening of Ca2+-activated K+ channels triggers early and delayed preconditioning against I/R injury independent of NOS in mice. American Journal of Physiology. Heart and Circulatory Physiology. 287: H2070-7. PMID 15217801 DOI: 10.1152/Ajpheart.00431.2004  0.429
2004 Okubo S, Tanabe Y, Takeda K, Kitayama M, Kanemitsu S, Kukreja RC, Takekoshi N. Pretreatment with tyrosine kinase inhibitor attenuates the reduction of apoptosis 24 h after ischemic preconditioning. The Japanese Journal of Physiology. 54: 143-51. PMID 15182421 DOI: 10.2170/Jjphysiol.54.143  0.451
2004 Das A, Ockaili R, Salloum F, Kukreja RC. Protein kinase C plays an essential role in sildenafil-induced cardioprotection in rabbits. American Journal of Physiology. Heart and Circulatory Physiology. 286: H1455-60. PMID 15020304 DOI: 10.1152/Ajpheart.01040.2003  0.776
2004 Kukreja RC, Ockaili R, Salloum F, Yin C, Hawkins J, Das A, Xi L. Cardioprotection with phosphodiesterase-5 inhibition--a novel preconditioning strategy. Journal of Molecular and Cellular Cardiology. 36: 165-73. PMID 14871543 DOI: 10.1016/J.Yjmcc.2003.11.001  0.757
2004 Bremer YA, Salloum F, Ockaili R, Chou EJ, Moskowitz WB, Kukreja RC. 1041-95 Sildenafil citrate (viagra) induces powerful cardioprotective effects following ischemia-reperfusion injury in infant rabbits Journal of the American College of Cardiology. 43: A256. DOI: 10.1016/S0735-1097(04)91087-X  0.74
2003 Kukreja RC, Ockaili R, Salloum F, Xi L. Sildenafil-induced cardioprotection in rabbits. Cardiovascular Research. 60: 700-1; author reply . PMID 14659816 DOI: 10.1016/J.Cardiores.2003.10.002  0.772
2003 Zhao TC, Kukreja RC. Protein kinase C-delta mediates adenosine A3 receptor-induced delayed cardioprotection in mouse. American Journal of Physiology. Heart and Circulatory Physiology. 285: H434-41. PMID 12793983 DOI: 10.1152/Ajpheart.00095.2003  0.446
2003 Salloum F, Yin C, Xi L, Kukreja RC. Sildenafil induces delayed preconditioning through inducible nitric oxide synthase-dependent pathway in mouse heart. Circulation Research. 92: 595-7. PMID 12637371 DOI: 10.1161/01.Res.0000066853.09821.98  0.498
2002 Jesse RL, Kukreja R. Rationale for the early clinical application of markers of ischemia in patients with suspected acute coronary syndromes. Cardiovascular Toxicology. 1: 125-33. PMID 12213984 DOI: 10.1385/Ct:1:2:125  0.408
2002 Ockaili R, Salloum F, Hawkins J, Kukreja RC. Sildenafil (Viagra) induces powerful cardioprotective effect via opening of mitochondrial K(ATP) channels in rabbits. American Journal of Physiology. Heart and Circulatory Physiology. 283: H1263-9. PMID 12181158 DOI: 10.1152/Ajpheart.00324.2002  0.762
2002 Xi L, Tekin D, Gursoy E, Salloum F, Levasseur JE, Kukreja RC. Evidence that NOS2 acts as a trigger and mediator of late preconditioning induced by acute systemic hypoxia. American Journal of Physiology. Heart and Circulatory Physiology. 283: H5-12. PMID 12063268 DOI: 10.1152/Ajpheart.00920.2001  0.479
2002 Zhao TC, Kukreja RC. Late preconditioning elicited by activation of adenosine A(3) receptor in heart: role of NF- kappa B, iNOS and mitochondrial K(ATP) channel. Journal of Molecular and Cellular Cardiology. 34: 263-77. PMID 11945020 DOI: 10.1006/Jmcc.2001.1510  0.439
2002 Tejero-Taldo MI, Gursoy E, Zhao TC, Kukreja RC. Alpha-adrenergic receptor stimulation produces late preconditioning through inducible nitric oxide synthase in mouse heart. Journal of Molecular and Cellular Cardiology. 34: 185-95. PMID 11851358 DOI: 10.1006/Jmcc.2001.1500  0.425
2001 Zhao TC, Taher MM, Valerie KC, Kukreja RC. p38 Triggers late preconditioning elicited by anisomycin in heart: Involvement of NF-κB and iNOS Circulation Research. 89: 915-922. PMID 11701619 DOI: 10.1161/Hh2201.099452  0.411
2001 Xi L, Tekin D, Bhargava P, Kukreja RC. Whole body hyperthermia and preconditioning of the heart: basic concepts, complexity, and potential mechanisms. International Journal of Hyperthermia : the Official Journal of European Society For Hyperthermic Oncology, North American Hyperthermia Group. 17: 439-55. PMID 11587081 DOI: 10.1080/02656730110064342  0.453
2001 Qiao L, Studer E, Leach K, McKinstry R, Gupta S, Decker R, Kukreja R, Valerie K, Nagarkatti P, El Deiry W, Molkentin J, Schmidt-Ullrich R, Fisher PB, Grant S, Hylemon PB, et al. Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: Inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis Molecular Biology of the Cell. 12: 2629-2645. PMID 11553704 DOI: 10.1091/Mbc.12.9.2629  0.323
2001 Tekin D, Xi L, Zhao T, Tejero-Taldo MI, Atluri S, Kukreja RC. Mitogen-activated protein kinases mediate heat shock-induced delayed protection in mouse heart American Journal of Physiology - Heart and Circulatory Physiology. 281. PMID 11454553 DOI: 10.1152/Ajpheart.2001.281.2.H523  0.46
2001 Kositprapa C, Ockaili RA, Kukreja RC. Bradykinin B2 receptor is involved in the late phase of preconditioning in rabbit heart. Journal of Molecular and Cellular Cardiology. 33: 1355-62. PMID 11437541 DOI: 10.1006/Jmcc.2000.1396  0.745
2001 Ockaili RA, Bhargava P, Kukreja RC. Chemical preconditioning with 3-nitropropionic acid in hearts: role of mitochondrial K(ATP) channel. American Journal of Physiology. Heart and Circulatory Physiology. 280: H2406-11. PMID 11299248 DOI: 10.1152/Ajpheart.2001.280.5.H2406  0.753
2001 Zhao TC, Hines DS, Kukreja RC. Adenosine-induced late preconditioning in mouse hearts: role of p38 MAP kinase and mitochondrial K(ATP) channels. American Journal of Physiology. Heart and Circulatory Physiology. 280: H1278-85. PMID 11179074 DOI: 10.1152/Ajpheart.2001.280.3.H1278  0.42
2001 Okubo S, Wildner O, Shah MR, Chelliah JC, Hess ML, Kukreja RC. Gene transfer of heat-shock protein 70 reduces infarct size in vivo after ischemia/reperfusion in the rabbit heart Circulation. 103: 877-881. PMID 11171798 DOI: 10.1161/01.Cir.103.6.877  0.426
2001 Zhao T, Kukreja RC. Adenosine A3 receptor induces late preconditioning by activation of nuclear factor κB and nitric oxide synthase in mouse heart Journal of Molecular and Cellular Cardiology. 33: A137. DOI: 10.1016/S0022-2828(01)90545-0  0.322
2000 Xi L, Kukreja RC. Pivotal role of nitric oxide in delayed pharmacological preconditioning against myocardial infarction Toxicology. 155: 37-44. PMID 11154795 DOI: 10.1016/S0300-483X(00)00275-4  0.516
2000 Okubo S, Bernardo NL, Elliott GT, Hess ML, Kukreja RC. Tyrosine kinase signaling in action potential shortening and expression of HSP72 in late preconditioning American Journal of Physiology - Heart and Circulatory Physiology. 279. PMID 11045962 DOI: 10.1152/Ajpheart.2000.279.5.H2269  0.422
2000 Zhao T, Xi L, Chelliah J, Levasseur JE, Kukreja RC. Inducible nitric oxide synthase mediates delayed myocardial protection induced by activation of adenosine A(1) receptors: evidence from gene-knockout mice. Circulation. 102: 902-7. PMID 10952960 DOI: 10.1161/01.Cir.102.8.902  0.382
1999 Ockaili R, Emani VR, Okubo S, Brown M, Krottapalli K, Kukreja RC. Opening of mitochondrial Kchannel induces early and delayed cardioprotective effect: role of nitric oxide. American Journal of Physiology. Heart and Circulatory Physiology. 277: H2425-H2434. PMID 29592265 DOI: 10.1152/ajpheart.1999.277.6.H2425  0.731
1999 Xi L, Salloum F, Tekin D, Jarrett NC, Kukreja RC. Glycolipid RC-552 induces delayed preconditioning-like effect via iNOS-dependent pathway in mice. American Journal of Physiology. Heart and Circulatory Physiology. 277: H2418-H2424. PMID 29592261 DOI: 10.1152/ajpheart.1999.277.6.H2418  0.379
1999 Ockaili R, Emani VR, Okubo S, Brown M, Krottapalli K, Kukreja RC. Opening of mitochondrial K(ATP) channel induces early and delayed cardioprotective effect: Role of nitric oxide American Journal of Physiology - Heart and Circulatory Physiology. 277. PMID 10600865 DOI: 10.1152/Ajpheart.1999.277.6.H2425  0.744
1999 Xi L, Salloum F, Tekin D, Jarrett NC, Kukreja RC. Glycolipid RC-552 induces delayed preconditioning-like effect via iNOS- dependent pathway in mice American Journal of Physiology - Heart and Circulatory Physiology. 277. PMID 10600864 DOI: 10.1152/Ajpheart.1999.277.6.H2418  0.481
1999 Xi L, Jarrett NC, Hess ML, Kukreja RC. Myocardial ischemia/reperfusion injury in the inducible nitric oxide synthase knockout mice Life Sciences. 65: 935-945. PMID 10465353 DOI: 10.1016/S0024-3205(99)00323-9  0.532
1999 Okubo S, Xi L, Bernardo NL, Yoshida KI, Kukreja RC. Myocardial preconditioning: Basic concepts and potential mechanisms Molecular and Cellular Biochemistry. 196: 3-12. PMID 10448897 DOI: 10.1023/A:1006949626070  0.401
1999 Kukreja RC. Role of K(ATP) channel in heat shock and pharmacological preconditioning Annals of the New York Academy of Sciences. 874: 211-221. PMID 10415533 DOI: 10.1111/J.1749-6632.1999.Tb09237.X  0.431
1999 Bernardo NL, Okubo S, Maaieh MM, Wood MA, Kukreja RC. Delayed preconditioning with adenosine is mediated by opening of ATP- sensitive K+ channels in rabbit heart American Journal of Physiology - Heart and Circulatory Physiology. 277. PMID 10409190 DOI: 10.1152/Ajpheart.1999.277.1.H128  0.455
1999 Kukreja RC, Qian YZ, Okubo S, Flaherty EE. Role of protein kinase C and 72 kDa heat shock protein in ischemic tolerance following heat stress in the rat heart Molecular and Cellular Biochemistry. 195: 123-131. PMID 10395076 DOI: 10.1023/A:1006977311448  0.443
1999 Xi L, Jarrett NC, Hess ML, Kukreja RC. Essential role of inducible nitric oxide synthase in monophosphoryl lipid A-induced late cardioprotection: Evidence from pharmacological inhibition and gene knockout mice Circulation. 99: 2157-2163. PMID 10217657 DOI: 10.1161/01.Cir.99.16.2157  0.46
1999 Bernardo NL, D'Angelo M, Okubo S, Joy A, Kukreja RC. Delayed ischemic preconditioning is mediated by opening of ATP-sensitive potassium channels in the rabbit heart American Journal of Physiology - Heart and Circulatory Physiology. 276. PMID 10199858 DOI: 10.1152/Ajpheart.1999.276.4.H1323  0.439
1999 Qian YZ, Bernardo NL, Nayeem MA, Chelliah J, Kukreja RC. Induction of 72-kDa heat shock protein does not produce second window of ischemic preconditioning in rat heart American Journal of Physiology - Heart and Circulatory Physiology. 276. PMID 9887036 DOI: 10.1152/Ajpheart.1999.276.1.H224  0.375
1999 Xi L, Hess ML, Kukreja RC. Myocardial protection by monophosphoryl lipid A: Potential mechanisms Cardiovascular Drug Reviews. 17: 265-280. DOI: 10.1111/J.1527-3466.1999.Tb00019.X  0.365
1999 Kukreja RC, Emani VR, Hess ML. Activated oxygen species in heart failure Heart Failure Reviews. 4: 121-132. DOI: 10.1023/A:1009816207172  0.366
1998 Gill RR, Gbur CJ, Fisher BJ, Hess ML, Fowler AA, Kukreja RC, Sholley MM. Heat shock provides delayed protection against oxidative injury in cultured human umbilical vein endothelial cells Journal of Molecular and Cellular Cardiology. 30: 2739-2749. PMID 9990544 DOI: 10.1006/Jmcc.1998.0837  0.346
1998 Xi L, Chelliah J, Nayeem MA, Levasseur JE, Hess ML, Kukreja RC. Whole body heat shock fails to protect mouse heart against ischemia/reperfusion injury: role of 72 kDa heat shock protein and antioxidant enzymes. Journal of Molecular and Cellular Cardiology. 30: 2213-27. PMID 9925359 DOI: 10.1006/Jmcc.1998.0781  0.484
1998 Xi L, Hess ML, Kukreja RC. Ischemic preconditioning in isolated perfused mouse heart: Reduction in infarct size without improvement of post-ischemic ventricular function Molecular and Cellular Biochemistry. 186: 69-77. PMID 9774187 DOI: 10.1023/A:1006811128561  0.483
1998 Janin Y, Qian YZ, Hoag JB, Elliott GT, Kukreja RC. Pharmacologic preconditioning with monophosphoryl lipid A is abolished by 5-hydroxydecanoate, a specific inhibitor of the K(ATP) channel Journal of Cardiovascular Pharmacology. 32: 337-342. PMID 9733344 DOI: 10.1097/00005344-199809000-00001  0.464
1998 Qian YZ, Shipley JB, Levasseur JE, Kukreja RC. Dissociation of heat shock proteins expression with ischemic tolerance by whole body hyperthermia in rat heart. Journal of Molecular and Cellular Cardiology. 30: 1163-72. PMID 9689590 DOI: 10.1006/Jmcc.1998.0680  0.422
1998 Kukreja RC, Bernardo NL, D'Angelo M. ATP-sensitive potassium (KATP) channel is involved in the second window of ischemic preconditioning in rabbit Pathophysiology. 5: 22. DOI: 10.1016/S0928-4680(98)80363-5  0.311
1998 Bernardo N, D'Angelo M, Jao A, Wood M, Kukreja R. ATP-sensitive potassium (K ATP ) channel blockers suppress monophasic action potential shortening and abolish the ‘second window of protection’ induced by ischemic preconditioning in rabbit hearts Journal of the American College of Cardiology. 31: 188. DOI: 10.1016/S0735-1097(98)81456-3  0.379
1997 Hoag JB, Qian YZ, Nayeem MA, D'Angelo M, Kukreja RC. ATP-sensitive potassium channel mediates delayed ischemic protection by heat stress in rabbit heart American Journal of Physiology - Heart and Circulatory Physiology. 273. PMID 9374785 DOI: 10.1152/Ajpheart.1997.273.5.H2458  0.39
1997 Nayeem MA, Elliott GT, Shah MR, Hastillo-Hess SL, Kukreja RC. Monophosphoryl lipid A protects adult rat cardiac myocytes with induction of the 72-kD heat shock protein: A cellular model of pharmacologic preconditioning Journal of Molecular and Cellular Cardiology. 29: 2305-2310. PMID 9281461 DOI: 10.1006/Jmcc.1997.0452  0.358
1997 Schultz JE, Qian YZ, Gross GJ, Kukreja RC. The ischemia-selective KATP channel antagonist, 5-hydroxydecanoate, blocks ischemic preconditioning in the rat heart. Journal of Molecular and Cellular Cardiology. 29: 1055-60. PMID 9152866 DOI: 10.1006/Jmcc.1996.0358  0.426
1997 Nayeem MA, Hess ML, Qian YZ, Loesser KE, Kukreja RC. Delayed preconditioning of cultured adult rat cardiac myocytes: Role of 70- And 90-kDa heat stress proteins American Journal of Physiology - Heart and Circulatory Physiology. 42. DOI: 10.1152/Ajpheart.1997.273.2.H861  0.344
1997 Kukreja RC, Janin Y. Reperfusion injury: Basic concepts and protection strategies Journal of Thrombosis and Thrombolysis. 4: 7-24. DOI: 10.1023/A:1017569611074  0.464
1996 Kontos MC, Shipley JB, Kukreja RC. Heat stress improves functional recovery and induces synthesis of 27- and 70-kDa heat shock proteins without preserving sarcoplasmic reticulum function in the ischemic rat heart. Journal of Molecular and Cellular Cardiology. 28: 1885-94. PMID 8899547 DOI: 10.1006/Jmcc.1996.0181  0.403
1996 Yoshida K, Maaieh MM, Shipley JB, Doloresco M, Bernardo NL, Qian YZ, Elliott GT, Kukreja RC. Monophosphoryl lipid A induces pharmacologic 'preconditioning' in rabbit hearts without concomitant expression of 70-kDa heat shock protein. Molecular and Cellular Biochemistry. 159: 73-80. PMID 8813712  0.367
1996 Qian YZ, Levasseur JE, Yoshida K, Kukreja RC. KATP channels in rat heart: blockade of ischemic and acetylcholine-mediated preconditioning by glibenclamide. The American Journal of Physiology. 271: H23-8. PMID 8760153 DOI: 10.1152/Ajpheart.1996.271.1.H23  0.419
1996 Yoshida K, Maaieh MM, Shipley JB, Doloresco M, Bernardo NL, Qian YZ, Elliott GT, Kukreja RC. Monophosphoryl lipid A induces pharmacologic 'preconditioning' in rabbit hearts without concomitant expression of 70-kDa heat shock protein. Molecular and Cellular Biochemistry. 156: 1-8. PMID 8709970 DOI: 10.1007/Bf00239312  0.471
1996 Qian YZ, Levasseur JE, Yoshida KI, Kukreja RC. KATP channels in rat heart: Blockade of ischemic and acetylcholine-mediated preconditioning by glibenclamide American Journal of Physiology - Heart and Circulatory Physiology. 40.  0.304
1995 Naseem SA, Kontos MC, Rao PS, Jesse RL, Hess ML, Kukreja RC. Sustain inhibition of nitric oxide by NG-nitro-l-arginine improves myocardial function following ischemia/reperfusion in isolated perfused rat heart Journal of Molecular and Cellular Cardiology. 27: 419-426. PMID 7760362 DOI: 10.1016/S0022-2828(08)80038-7  0.433
1995 Hess ML, Kukreja RC. Free radicals, calcium homeostasis, heat shock proteins, and myocardial stunning The Annals of Thoracic Surgery. 60: 760-766. PMID 7677533 DOI: 10.1016/0003-4975(95)00574-5  0.368
1994 Hess ML, Kukreja RC. Myocardial stunning Journal of Cardiac Surgery. 9: 382-386. PMID 8069024  0.362
1994 Kukreja RC, Kontos MC, Loesser KE, Batra SK, Qian YZ, Gbur CJ, Naseem SA, Jesse RL, Hess ML. Oxidant stress increases heat shock protein 70 mRNA in isolated perfused rat heart American Journal of Physiology - Heart and Circulatory Physiology. 267. PMID 7810720 DOI: 10.1152/Ajpheart.1994.267.6.H2213  0.386
1993 Kukreja RC, Loesser KE, Kearns AA, Naseem SA, Hess ML. Protective effects of histidine during ischemia-reperfusion in isolated perfused rat hearts American Journal of Physiology - Heart and Circulatory Physiology. 264. PMID 8498550 DOI: 10.1152/Ajpheart.1993.264.5.H1370  0.391
1993 Okabe E, Takahashi Ss, Norisue M, Manson NH, Kukreja RC, Hess ML, Ito H. The effect of hypochlorous acid and hydrogen peroxide on coronary flow and arrhythmogenesis in myocardial ischemia and reperfusion European Journal of Pharmacology: Environmental Toxicology And. 248: 33-39. PMID 8393407 DOI: 10.1016/0926-6917(93)90022-I  0.464
1992 Kukreja RC, Hess ML. The oxygen free radical system: From equations through membrane-protein interactions to cardiovascular injury and protection Cardiovascular Research. 26: 641-655. PMID 1423428 DOI: 10.1093/Cvr/26.7.641  0.359
1992 Vinnikova AK, Kukreja RC, Hess ML. Singlet oxygen-induced inhibition of cardiac sarcolemmal Na+K+-ATPase Journal of Molecular and Cellular Cardiology. 24: 465-470. PMID 1321912 DOI: 10.1016/0022-2828(92)91835-S  0.336
1992 Kukreja RC, Jesse RL, Hess ML. Singlet oxygen: a potential culprit in myocardial injury? Molecular and Cellular Biochemistry. 111: 17-24. PMID 1317003 DOI: 10.1007/Bf00229569  0.351
1991 Kukreja RC, Kearns AA, Zweier JL, Kuppusamy P, Hess ML. Singlet oxygen interaction with Ca2+-ATPase of cardiac sarcoplasmic reticulum Circulation Research. 69: 1003-1014. PMID 1657435 DOI: 10.1161/01.Res.69.4.1003  0.316
1991 KUKREJA R. Protective effects of histidine during ischemia/pepefusion injury in the isolated perfused rat heart: Possible involvement of singlet oxygen*1 Journal of Molecular and Cellular Cardiology. 23: S47. DOI: 10.1016/0022-2828(91)91463-2  0.414
1990 Kontos HA, Wei EP, Kukreja RC, Ellis EF, Hess ML. Differences in endothelium-dependent cerebral dilation by bradykinin and acetylcholine. The American Journal of Physiology. 258: H1261-6. PMID 2337161 DOI: 10.1152/Ajpheart.1990.258.5.H1261  0.304
1990 Kukreja RC, Weaver AB, Hess ML. Sarcolemmal Na+-K+-ATPase: Inactivation by neutrophil-derived free radicals and oxidants American Journal of Physiology - Heart and Circulatory Physiology. 259. PMID 2173423 DOI: 10.1152/Ajpheart.1990.259.5.H1330  0.303
1990 Kukreja RC, Kontos HA, Hess ML. Captopril and enalaprilat do not scavenge the superoxide anion The American Journal of Cardiology. 65: 24-27. PMID 2159692 DOI: 10.1016/0002-9149(90)90121-G  0.321
1989 Kontos HA, Wei EP, Povlishock JT, Kukreja RC, Hess ML. Inhibition by arachidonate of cerebral arteriolar dilation from acetylcholine. The American Journal of Physiology. 256: H665-71. PMID 2538081 DOI: 10.1152/Ajpheart.1989.256.3.H665  0.303
1989 Kukreja RC, Weaver AB, Hess ML. Stimulated human neutrophils damage cardiac sarcoplasmic reticulum function by generation of oxidants Biochimica Et Biophysica Acta - General Subjects. 990: 198-205. PMID 2537110 DOI: 10.1016/S0304-4165(89)80034-0  0.366
1988 Kukreja RC, Okabe E, Schrier GM, Hess ML. Oxygen radical-mediated lipid peroxidation and inhibition of Ca2+-ATPase activity of cardiac sarcoplasmic reticulum Archives of Biochemistry and Biophysics. 261: 447-457. PMID 2833166 DOI: 10.1016/0003-9861(88)90361-X  0.333
1988 Kukreja R, Weaver A, Hess M. Stimulated neutrophils damage cardiac sarcoplasmic function by generation of oxidants Journal of Molecular and Cellular Cardiology. 20: 14. DOI: 10.1016/S0022-2828(98)90042-6  0.32
1987 Bolli R, Zhu WX, Hartley CJ, Michael LH, Repine JE, Hess ML, Kukreja RC, Roberts R. Attenuation of dysfunction in the postischemic 'stunned' myocardium by dimethylthiourea Circulation. 76: 458-468. PMID 3111744 DOI: 10.1161/01.Cir.76.2.458  0.398
1987 KUKREJA R, OKABE E, HESS M. Evidence of hydroxyl radical mediated inhibition of (Ca2+-Mg2+)-ATPase activity and lipid peroxidation of cardiac sarcoplasmic reticulum Journal of Molecular and Cellular Cardiology. 19: S79-S79. DOI: 10.1016/S0022-2828(87)80861-1  0.319
1987 MANSON N, KUKREJA R, LEBOLT W, HESS M, HEARSE D. Effect of long lived oxidants on coronary flow and arrhythmogenesis in the isolated perfused rat heart Journal of Molecular and Cellular Cardiology. 19: S69-S69. DOI: 10.1016/S0022-2828(87)80831-3  0.326
1986 Kukreja RC, Kontos HA, Hess ML, Ellis EF. PGH synthase and lipoxygenase generate superoxide in the presence of NADH or NADPH. Circulation Research. 59: 612-9. PMID 3028671 DOI: 10.1161/01.Res.59.6.612  0.311
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