Philip W. Hinds - Publications

Affiliations: 
Biochemistry Sackler School of Graduate Biomedical Sciences (Tufts University) 
Area:
Molecular Biology

103 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 McRee SK, Bayer AL, Pietruska J, Tsichlis PN, Hinds PW. AKT2 Loss Impairs BRAF-Mutant Melanoma Metastasis. Cancers. 15. PMID 37894325 DOI: 10.3390/cancers15204958  0.381
2023 McRee SK, Bayer AL, Pietruska J, Tsichlis PN, Hinds PW. AKT2 Loss Impairs BRAF-Mutant Melanoma Metastasis. Biorxiv : the Preprint Server For Biology. PMID 37662310 DOI: 10.1101/2023.08.24.554685  0.378
2022 Bayer AL, Pietruska J, Farrell J, McRee S, Alcaide P, Hinds PW. AKT1 Is Required for a Complete Palbociclib-Induced Senescence Phenotype in BRAF-V600E-Driven Human Melanoma. Cancers. 14. PMID 35158840 DOI: 10.3390/cancers14030572  0.426
2020 Polytarchou C, Hatziapostolou M, Yau TO, Christodoulou N, Hinds PW, Kottakis F, Sanidas I, Tsichlis PN. Akt3 induces oxidative stress and DNA damage by activating the NADPH oxidase via phosphorylation of p47. Proceedings of the National Academy of Sciences of the United States of America. PMID 33139577 DOI: 10.1073/pnas.2017830117  0.37
2019 Baugh LM, Watson MC, Kemmerling EC, Hinds P, Huggins GS, Black LD. Knockdown of CD44 Expression Decreases Valve Interstitial Cell Calcification in Vitro. American Journal of Physiology. Heart and Circulatory Physiology. PMID 30951363 DOI: 10.1152/Ajpheart.00123.2018  0.338
2018 Bellutti F, Tigan AS, Nebenfuehr S, Dolezal M, Zojer M, Grausenburger R, Hartenberger S, Kollmann S, Doma E, Prchal-Murphy M, Uras IZ, Höllein A, Neuberg DS, Ebert BL, Ringler A, ... ... Hinds PW, et al. CDK6 Antagonizes p53-Induced Responses during Tumorigenesis. Cancer Discovery. PMID 29899063 DOI: 10.1158/2159-8290.Cd-17-0912  0.496
2018 Caron N, Genin EC, Marlier Q, Verteneuil S, Beukelaers P, Morel L, Hu MG, Hinds PW, Nguyen L, Vandenbosch R, Malgrange B. Proliferation of hippocampal progenitors relies on p27-dependent regulation of Cdk6 kinase activity. Cellular and Molecular Life Sciences : Cmls. PMID 29728713 DOI: 10.1007/S00018-018-2832-X  0.486
2018 Freytsis M, Baugh L, Liu Z, Georgakoudi I, Hinds PW, Black LD, Huggins GS. Conditional deletion of RB1 in the Tie2 lineage leads to aortic valve regurgitation. Plos One. 13: e0190623. PMID 29304157 DOI: 10.1371/Journal.Pone.0190623  0.313
2017 Hinds P, Pietruska J. Senescence and tumor suppression. F1000research. 6: 2121. PMID 29263785 DOI: 10.12688/F1000Research.11671.1  0.466
2017 Amulic B, Knackstedt SL, Abu Abed U, Deigendesch N, Harbort CJ, Caffrey BE, Brinkmann V, Heppner FL, Hinds PW, Zychlinsky A. Cell-Cycle Proteins Control Production of Neutrophil Extracellular Traps. Developmental Cell. PMID 29103955 DOI: 10.1016/J.Devcel.2017.10.013  0.428
2017 Uras IZ, Scheicher RM, Kollmann K, Glösmann M, Prchal-Murphy M, Tigan AS, Fux DA, Altamura S, Neves J, Muckenthaler M, Bennett KL, Kubicek S, Hinds PW, von Lindern M, Sexl V. Cdk6 contributes to cytoskeletal stability in erythroid cells. Haematologica. PMID 28255017 DOI: 10.3324/Haematol.2016.159947  0.476
2017 McRee SK, Pietruska JR, Dignan E, Hinds PW. Abstract B07: Differential roles for AKT isoforms in BRAF mutant melanoma Clinical Cancer Research. 23. DOI: 10.1158/1557-3265.Pmccavuln16-B07  0.47
2016 Ballatori SE, Hinds PW. Osteosarcoma: prognosis plateau warrants retinoblastoma pathway targeted therapy. Signal Transduction and Targeted Therapy. 1: 16001. PMID 29263893 DOI: 10.1038/Sigtrans.2016.1  0.362
2016 Kohrt D, Hinds P, Ford H, Grossel M. Abstract A38: In vitro and in vivo interaction of Cdk6 and Eya2 indicate potential crosstalk Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Devbiolca15-A38  0.379
2016 Hinds PW, Enos M, Kong E, Dignan E, Gunduz V, Pietruska J. Abstract B04: Novel Methods to Target RB Pathway Disruption in Osteosarcoma Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Cellcycle16-B04  0.759
2015 Jena N, Sheng J, Hu JK, Li W, Zhou W, Lee G, Tsichlis N, Pathak A, Brown N, Deshpande A, Luo C, Hu GF, Hinds PW, Van Etten RA, Hu MG. CDK6-mediated repression of CD25 is required for induction and maintenance of Notch1-induced T cell acute lymphoblastic leukemia. Leukemia. PMID 26707936 DOI: 10.1038/Leu.2015.353  0.601
2015 Cao J, Dai X, Wan L, Wang H, Zhang J, Goff PS, Sviderskaya EV, Xuan Z, Xu Z, Xu X, Hinds P, Flaherty KT, Faller DV, Goding CR, Wang Y, et al. The E3 ligase APC/CCdh1 promotes ubiquitylation-mediated proteolysis of PAX3 to suppress melanocyte proliferation and melanoma growth. Science Signaling. 8: ra87. PMID 26329581 DOI: 10.1126/Scisignal.Aab1995  0.447
2015 Sedic M, Skibinski A, Brown N, Gallardo M, Mulligan P, Martinez P, Keller PJ, Glover E, Richardson AL, Cowan J, Toland AE, Ravichandran K, Riethman H, Naber SP, Näär AM, ... ... Hinds PW, et al. Haploinsufficiency for BRCA1 leads to cell-type-specific genomic instability and premature senescence. Nature Communications. 6: 7505. PMID 26106036 DOI: 10.1038/Ncomms8505  0.431
2015 Luo C, Pietruska JR, Sheng J, Bronson RT, Hu MG, Cui R, Hinds PW. Expression of oncogenic BRAF(V600E) in melanocytes induces Schwannian differentiation in vivo. Pigment Cell & Melanoma Research. PMID 26036358 DOI: 10.1111/Pcmr.12384  0.621
2015 Pietruska JR, Luo C, Hinds PW. Abstract A19: Expression of BRAFV600E in melanocytes induces Schwannian differentiation in vivo Cancer Research. 75. DOI: 10.1158/1538-7445.Mel2014-A19  0.446
2014 Hinds PW. A little pRB can lead to big problems. Cancer Discovery. 4: 764-5. PMID 25002614 DOI: 10.1158/2159-8290.Cd-14-0518  0.464
2014 Kottakis F, Foltopoulou P, Sanidas I, Keller P, Wronski A, Dake BT, Ezell SA, Shen Z, Naber SP, Hinds PW, McNiel E, Kuperwasser C, Tsichlis PN. NDY1/KDM2B functions as a master regulator of polycomb complexes and controls self-renewal of breast cancer stem cells. Cancer Research. 74: 3935-46. PMID 24853546 DOI: 10.1158/0008-5472.Can-13-2733  0.442
2014 Sheng J, Luo C, Jiang Y, Hinds PW, Xu Z, Hu GF. Transcription of angiogenin and ribonuclease 4 is regulated by RNA polymerase III elements and a CCCTC binding factor (CTCF)-dependent intragenic chromatin loop. The Journal of Biological Chemistry. 289: 12520-34. PMID 24659782 DOI: 10.1074/Jbc.M114.551762  0.589
2014 Kohrt D, Crary J, Zimmer M, Patrick AN, Ford HL, Hinds PW, Grossel MJ. CDK6 binds and promotes the degradation of the EYA2 protein. Cell Cycle (Georgetown, Tex.). 13: 62-71. PMID 24196439 DOI: 10.4161/Cc.26755  0.496
2014 Sheng J, Luo C, Jiang Y, Hinds PW, Xu Z, Hu G. Abstract 1401: Transcription of angiogenin and ribonuclease 4 is regulated by RNA polymerase III elements and a CTCF-dependent intragenic chromatin loop Cancer Research. 74: 1401-1401. DOI: 10.1158/1538-7445.Am2014-1401  0.593
2014 Brown NE, Hinds PW. Tumor Suppressor Genes The Molecular Basis of Cancer: Fourth Edition. 35-46.e1. DOI: 10.1016/0968-0004(91)90105-5  0.341
2013 Kansara M, Leong HS, Lin DM, Popkiss S, Pang P, Garsed DW, Walkley CR, Cullinane C, Ellul J, Haynes NM, Hicks R, Kuijjer ML, Cleton-Jansen AM, Hinds PW, Smyth MJ, et al. Immune response to RB1-regulated senescence limits radiation-induced osteosarcoma formation. The Journal of Clinical Investigation. 123: 5351-60. PMID 24231354 DOI: 10.1172/Jci70559  0.422
2013 Luo C, Sheng J, Hu MG, Haluska FG, Cui R, Xu Z, Tsichlis PN, Hu GF, Hinds PW. Loss of ARF sensitizes transgenic BRAFV600E mice to UV-induced melanoma via suppression of XPC. Cancer Research. 73: 4337-48. PMID 23650282 DOI: 10.1158/0008-5472.Can-12-4454  0.619
2012 Brown NE, Jeselsohn R, Bihani T, Hu MG, Foltopoulou P, Kuperwasser C, Hinds PW. Cyclin D1 activity regulates autophagy and senescence in the mammary epithelium. Cancer Research. 72: 6477-89. PMID 23041550 DOI: 10.1158/0008-5472.Can-11-4139  0.378
2012 Foley CJ, Luo C, O'Callaghan K, Hinds PW, Covic L, Kuliopulos A. Matrix metalloprotease-1a promotes tumorigenesis and metastasis Journal of Biological Chemistry. 287: 24330-24338. PMID 22573325 DOI: 10.1074/Jbc.M112.356303  0.64
2012 Gündüz V, Kong E, Bryan CD, Hinds PW. Loss of the retinoblastoma tumor suppressor protein in murine calvaria facilitates immortalization of osteoblast-adipocyte bipotent progenitor cells characterized by low expression of N-cadherin. Molecular and Cellular Biology. 32: 2561-9. PMID 22547682 DOI: 10.1128/Mcb.06453-11  0.735
2012 Zhang W, Vazquez B, Andreeva V, Spear D, Kong E, Hinds PW, Yelick PC. Discrete phosphorylated retinoblastoma protein isoform expression in mouse tooth development. Journal of Molecular Histology. 43: 281-8. PMID 22476877 DOI: 10.1007/S10735-012-9404-4  0.78
2011 Bihani T, Hinds PW. Mitosis hit with an ATM transaction fee: aurora B-mediated activation of ATM during mitosis. Molecular Cell. 44: 513-4. PMID 22099300 DOI: 10.1016/J.Molcel.2011.11.001  0.352
2011 Hu MG, Deshpande A, Schlichting N, Hinds EA, Mao C, Dose M, Hu GF, Van Etten RA, Gounari F, Hinds PW. CDK6 kinase activity is required for thymocyte development. Blood. 117: 6120-31. PMID 21508411 DOI: 10.1182/Blood-2010-08-300517  0.456
2011 Huang M, Sage C, Tang Y, Lee SG, Petrillo M, Hinds PW, Chen ZY. Overlapping and distinct pRb pathways in the mammalian auditory and vestibular organs. Cell Cycle (Georgetown, Tex.). 10: 337-51. PMID 21239885 DOI: 10.4161/Cc.10.2.14640  0.488
2010 Sosa-García B, Gunduz V, Vázquez-Rivera V, Cress WD, Wright G, Bian H, Hinds PW, Santiago-Cardona PG. A role for the retinoblastoma protein as a regulator of mouse osteoblast cell adhesion: implications for osteogenesis and osteosarcoma formation. Plos One. 5: e13954. PMID 21085651 DOI: 10.1371/Journal.Pone.0013954  0.797
2010 Mao D, Hinds PW. p35 is required for CDK5 activation in cellular senescence. The Journal of Biological Chemistry. 285: 14671-80. PMID 20181942 DOI: 10.1074/Jbc.M109.066118  0.467
2010 Jeselsohn R, Brown NE, Arendt L, Klebba I, Hu MG, Kuperwasser C, Hinds PW. Cyclin D1 kinase activity is required for the self-renewal of mammary stem and progenitor cells that are targets of MMTV-ErbB2 tumorigenesis. Cancer Cell. 17: 65-76. PMID 20129248 DOI: 10.1016/J.Ccr.2009.11.024  0.418
2009 Lazebnik MB, Tussie-Luna MI, Hinds PW, Roy AL. Williams-Beuren syndrome-associated transcription factor TFII-I regulates osteogenic marker genes. The Journal of Biological Chemistry. 284: 36234-9. PMID 19880526 DOI: 10.1074/Jbc.C109.063115  0.393
2009 Hinds PW. Keeping quiet: a key role for dipeptidyl peptidase 2. Cell Cycle (Georgetown, Tex.). 8: 2683-4. PMID 19717973 DOI: 10.4161/Cc.8.17.9647  0.413
2009 Kohrt DM, Crary JI, Gocheva V, Hinds PW, Grossel MJ. Distinct subcellular distribution of cyclin dependent kinase 6. Cell Cycle (Georgetown, Tex.). 8: 2837-43. PMID 19667758 DOI: 10.4161/Cc.8.17.9521  0.46
2009 Goel VK, Ibrahim N, Jiang G, Singhal M, Fee S, Flotte T, Westmoreland S, Haluska FS, Hinds PW, Haluska FG. Melanocytic nevus-like hyperplasia and melanoma in transgenic BRAFV600E mice. Oncogene. 28: 2289-98. PMID 19398955 DOI: 10.1038/Onc.2009.95  0.399
2009 Hu MG, Deshpande A, Enos M, Mao D, Hinds EA, Hu GF, Chang R, Guo Z, Dose M, Mao C, Tsichlis PN, Gounari F, Hinds PW. A requirement for cyclin-dependent kinase 6 in thymocyte development and tumorigenesis. Cancer Research. 69: 810-8. PMID 19155308 DOI: 10.1158/0008-5472.Can-08-2473  0.74
2009 Zhang X, Neganova I, Przyborski S, Yang C, Cooke M, Atkinson SP, Anyfantis G, Fenyk S, Keith WN, Hoare SF, Hughes O, Strachan T, Stojkovic M, Hinds PW, Armstrong L, et al. A role for NANOG in G1 to S transition in human embryonic stem cells through direct binding of CDK6 and CDC25A. The Journal of Cell Biology. 184: 67-82. PMID 19139263 DOI: 10.1083/Jcb.200801009  0.44
2009 Brown NE, Kuperwasser C, Hinds PW. Abstract B26: Lack of cyclin D1 kinase activity leads to reduced levels of ErbB2-induced senescence and activation of the Wnt signaling pathway in the mammary gland Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-B26  0.513
2009 Gunduz V, Cardona PS, Hinds PW. Abstract B12: RB1‐mediated regulation of osteoblast migration Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-B12  0.78
2009 Kong E, Gutierrez G, Thomas D, Hinds P. Abstract A10: Increased mesenchymal progenitor cells in RB1−/− bone Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-A10  0.708
2008 Gutierrez GM, Kong E, Sabbagh Y, Brown NE, Lee JS, Demay MB, Thomas DM, Hinds PW. Impaired bone development and increased mesenchymal progenitor cells in calvaria of RB1-/- mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 18402-7. PMID 19020086 DOI: 10.1073/Pnas.0805925105  0.784
2008 Piscopo DM, Hinds PW. A role for the cyclin box in the ubiquitin-mediated degradation of cyclin G1. Cancer Research. 68: 5581-90. PMID 18632610 DOI: 10.1158/0008-5472.Can-07-6346  0.392
2008 Hinds PW. Too much of a good thing: the Prl-3 in p53's oyster. Molecular Cell. 30: 260-1. PMID 18471970 DOI: 10.1016/J.Molcel.2008.04.006  0.419
2007 Wang Y, Ray SK, Hinds PW, Leiter AB. The retinoblastoma protein, RB, is required for gastrointestinal endocrine cells to exit the cell cycle, but not for hormone expression. Developmental Biology. 311: 478-86. PMID 17936268 DOI: 10.1016/J.Ydbio.2007.08.052  0.536
2007 Landis MW, Brown NE, Baker GL, Shifrin A, Das M, Geng Y, Sicinski P, Hinds PW. The LxCxE pRb interaction domain of cyclin D1 is dispensable for murine development. Cancer Research. 67: 7613-20. PMID 17699765 DOI: 10.1158/0008-5472.Can-07-1207  0.371
2007 Tsichlis PN, Hatziapostolou M, Hinds PW. Timing is everything: regulation of Cdk1 and aneuploidy. Developmental Cell. 12: 477-9. PMID 17419986 DOI: 10.1016/J.Devcel.2007.03.010  0.46
2007 Yang HS, Hinds PW. pRb-mediated control of epithelial cell proliferation and Indian hedgehog expression in mouse intestinal development. Bmc Developmental Biology. 7: 6. PMID 17257418 DOI: 10.1186/1471-213X-7-6  0.47
2006 Deshpande A, Hinds PW. The retinoblastoma protein in osteoblast differentiation and osteosarcoma. Current Molecular Medicine. 6: 809-17. PMID 17100605 DOI: 10.2174/1566524010606070809  0.444
2006 Lee JS, Thomas DM, Gutierrez G, Carty SA, Yanagawa S, Hinds PW. HES1 cooperates with pRb to activate RUNX2-dependent transcription. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 21: 921-33. PMID 16753023 DOI: 10.1359/Jbmr.060303  0.407
2006 Hinds PW. A confederacy of kinases: Cdk2 and Cdk4 conspire to control embryonic cell proliferation. Molecular Cell. 22: 432-3. PMID 16713571 DOI: 10.1016/J.Molcel.2006.05.006  0.435
2006 Sage C, Huang M, Vollrath MA, Brown MC, Hinds PW, Corey DP, Vetter DE, Chen ZY. Essential role of retinoblastoma protein in mammalian hair cell development and hearing. Proceedings of the National Academy of Sciences of the United States of America. 103: 7345-50. PMID 16648263 DOI: 10.1073/Pnas.0510631103  0.466
2006 Yang HS, Hinds PW. Phosphorylation of ezrin by cyclin-dependent kinase 5 induces the release of Rho GDP dissociation inhibitor to inhibit Rac1 activity in senescent cells. Cancer Research. 66: 2708-15. PMID 16510591 DOI: 10.1158/0008-5472.Can-05-3141  0.511
2006 Landis MW, Pawlyk BS, Li T, Sicinski P, Hinds PW. Cyclin D1-dependent kinase activity in murine development and mammary tumorigenesis. Cancer Cell. 9: 13-22. PMID 16413468 DOI: 10.1016/J.Ccr.2005.12.019  0.371
2006 Grossel MJ, Hinds PW. From cell cycle to differentiation: an expanding role for cdk6. Cell Cycle (Georgetown, Tex.). 5: 266-70. PMID 16410727 DOI: 10.4161/Cc.5.3.2385  0.468
2006 Grossel MJ, Hinds PW. Beyond the cell cycle: a new role for Cdk6 in differentiation. Journal of Cellular Biochemistry. 97: 485-93. PMID 16294322 DOI: 10.1002/Jcb.20712  0.513
2005 Marsit CJ, Wiencke JK, Nelson HH, Kim DH, Hinds PW, Aldape K, Kelsey KT. Alterations of 9p in squamous cell carcinoma and adenocarcinoma of the lung: association with smoking, TP53, and survival. Cancer Genetics and Cytogenetics. 162: 115-21. PMID 16213358 DOI: 10.1016/J.Cancergencyto.2005.04.001  0.334
2005 Marsit CJ, Zheng S, Aldape K, Hinds PW, Nelson HH, Wiencke JK, Kelsey KT. PTEN expression in non-small-cell lung cancer: evaluating its relation to tumor characteristics, allelic loss, and epigenetic alteration. Human Pathology. 36: 768-76. PMID 16084946 DOI: 10.1016/J.Humpath.2005.05.006  0.47
2005 Gutierrez GM, Kong E, Hinds PW. Master or slave: the complex relationship of RBP2 and pRb. Cancer Cell. 7: 501-2. PMID 15950898 DOI: 10.1016/J.Ccr.2005.05.021  0.776
2005 Deshpande A, Sicinski P, Hinds PW. Cyclins and cdks in development and cancer: a perspective. Oncogene. 24: 2909-15. PMID 15838524 DOI: 10.1038/Sj.Onc.1208618  0.468
2005 Baker GL, Landis MW, Hinds PW. Multiple functions of D-type cyclins can antagonize pRb-mediated suppression of proliferation. Cell Cycle (Georgetown, Tex.). 4: 330-8. PMID 15684604 DOI: 10.4161/Cc.4.2.1485  0.376
2005 Sage C, Huang M, Karimi K, Gutierrez G, Vollrath MA, Zhang DS, García-Añoveros J, Hinds PW, Corwin JT, Corey DP, Chen ZY. Proliferation of functional hair cells in vivo in the absence of the retinoblastoma protein. Science (New York, N.Y.). 307: 1114-8. PMID 15653467 DOI: 10.1126/Science.1106642  0.514
2005 Marsit CJ, Kim DH, Liu M, Hinds PW, Wiencke JK, Nelson HH, Kelsey KT. Hypermethylation of RASSF1A and BLU tumor suppressor genes in non-small cell lung cancer: implications for tobacco smoking during adolescence. International Journal of Cancer. 114: 219-23. PMID 15540210 DOI: 10.1002/Ijc.20714  0.309
2004 Thomas DM, Johnson SA, Sims NA, Trivett MK, Slavin JL, Rubin BP, Waring P, McArthur GA, Walkley CR, Holloway AJ, Diyagama D, Grim JE, Clurman BE, Bowtell DD, Lee JS, ... ... Hinds PW, et al. Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma. The Journal of Cell Biology. 167: 925-34. PMID 15583032 DOI: 10.1083/Jcb.200409187  0.583
2004 Marsit CJ, Hasegawa M, Hirao T, Kim DH, Aldape K, Hinds PW, Wiencke JK, Nelson HH, Kelsey KT. Loss of heterozygosity of chromosome 3p21 is associated with mutant TP53 and better patient survival in non-small-cell lung cancer. Cancer Research. 64: 8702-7. PMID 15574780 DOI: 10.1158/0008-5472.Can-04-2558  0.386
2004 Levine AJ, Finlay CA, Hinds PW. P53 is a tumor suppressor gene. Cell. 116: S67-9, 1 p following. PMID 15055586 DOI: 10.1016/S0092-8674(04)00036-4  0.348
2004 Alexander K, Yang HS, Hinds PW. Cellular senescence requires CDK5 repression of Rac1 activity. Molecular and Cellular Biology. 24: 2808-19. PMID 15024070 DOI: 10.1128/Mcb.24.7.2808-2819.2004  0.438
2003 Yang HS, Alexander K, Santiago P, Hinds PW. ERM proteins and Cdk5 in cellular senescence. Cell Cycle (Georgetown, Tex.). 2: 517-20. PMID 14504464 DOI: 10.4161/Cc.2.6.582  0.508
2003 Alexander K, Yang HS, Hinds PW. pRb inactivation in senescent cells leads to an E2F-dependent apoptosis requiring p73. Molecular Cancer Research : McR. 1: 716-28. PMID 12939397  0.397
2003 Yang HS, Hinds PW. Increased ezrin expression and activation by CDK5 coincident with acquisition of the senescent phenotype. Molecular Cell. 11: 1163-76. PMID 12769842 DOI: 10.1016/S1097-2765(03)00135-7  0.538
2003 Thomas DM, Yang HS, Alexander K, Hinds PW. Role of the retinoblastoma protein in differentiation and senescence. Cancer Biology & Therapy. 2: 124-30. PMID 12750549 DOI: 10.4161/Cbt.2.2.235  0.526
2003 Hinds PW. Cdk2 dethroned as master of S phase entry. Cancer Cell. 3: 305-7. PMID 12726855 DOI: 10.1016/S1535-6108(03)00084-9  0.513
2003 Piboonniyom SO, Duensing S, Swilling NW, Hasskarl J, Hinds PW, Münger K. Abrogation of the retinoblastoma tumor suppressor checkpoint during keratinocyte immortalization is not sufficient for induction of centrosome-mediated genomic instability. Cancer Research. 63: 476-83. PMID 12543805  0.401
2002 Todd R, Hinds PW, Munger K, Rustgi AK, Opitz OG, Suliman Y, Wong DT. Cell cycle dysregulation in oral cancer Critical Reviews in Oral Biology and Medicine. 13: 51-61. PMID 12097237 DOI: 10.1177/154411130201300106  0.363
2002 Yang H, Williams BO, Hinds PW, Shih TS, Jacks T, Bronson RT, Livingston DM. Tumor suppression by a severely truncated species of retinoblastoma protein Molecular and Cellular Biology. 22: 3103-3110. PMID 11940667 DOI: 10.1128/Mcb.22.9.3103-3110.2002  0.39
2002 Piboonniyom SO, Timmermann S, Hinds P, Münger K. Aberrations in the MTS1 tumor suppressor locus in oral squamous cell carcinoma lines preferentially affect the INK4A gene and result in increased cdk6 activity. Oral Oncology. 38: 179-86. PMID 11854066 DOI: 10.1016/S1368-8375(01)00042-2  0.464
2001 Thomas DM, Carty SA, Piscopo DM, Lee JS, Wang WF, Forrester WC, Hinds PW. The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation Molecular Cell. 8: 303-316. PMID 11545733 DOI: 10.1016/S1097-2765(01)00327-6  0.483
2001 Alexander K, Hinds PW. Requirement for p27KIP1 in retinoblastoma protein-mediated senescence Molecular and Cellular Biology. 21: 3616-3631. PMID 11340156 DOI: 10.1128/Mcb.21.11.3616-3631.2001  0.502
2000 Marin MC, Jost CA, Brooks LA, Irwin MS, O'Nions J, Tidy JA, James N, McGregor JM, Harwood CA, Yulug IG, Vousden KH, Allday MJ, Gusterson B, Ikawa S, Hinds PW, et al. A common polymorphism acts as an intragenic modifier of mutant p53 behaviour Nature Genetics. 25: 47-54. PMID 10802655 DOI: 10.1038/75586  0.331
1999 Grossel MJ, Baker GL, Hinds PW. cdk6 can shorten G(1) phase dependent upon the N-terminal INK4 interaction domain. The Journal of Biological Chemistry. 274: 29960-7. PMID 10514479 DOI: 10.1074/Jbc.274.42.29960  0.465
1998 Timmermann S, Hinds PW, Münger K. Re-expression of endogenous p16(ink4a) in oral squamous cell carcinoma lines by 5-aza-2'-deoxycytidine treatment induces a senescence-like state Oncogene. 17: 3445-3453. PMID 10030668 DOI: 10.1038/Sj.Onc.1202244  0.448
1998 Tiemann F, Hinds PW. Induction of DNA synthesis and apoptosis by regulated inactivation of a temperature-sensitive retinoblastoma protein. The Embo Journal. 17: 1040-52. PMID 9463382 DOI: 10.1093/Emboj/17.4.1040  0.498
1997 Neuman E, Ladha MH, Lin N, Upton TM, Miller SJ, DiRenzo J, Pestell RG, Hinds PW, Dowdy SF, Brown M, Ewen ME. Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4. Molecular and Cellular Biology. 17: 5338-47. PMID 9271411 DOI: 10.1128/Mcb.17.9.5338  0.338
1997 Timmermann S, Hinds PW, Münger K. Elevated activity of cyclin-dependent kinase 6 in human squamous cell carcinoma lines Cell Growth and Differentiation. 8: 361-370. PMID 9101082  0.324
1996 Latham KM, Eastman SW, Wong A, Hinds PW. Inhibition of p53-mediated growth arrest by overexpression of cyclin-dependent kinases. Molecular and Cellular Biology. 16: 4445-55. PMID 8754845  0.309
1995 Hinds PW. The retinoblastoma tumor suppressor protein Current Opinion in Genetics and Development. 5: 79-83. PMID 7749330 DOI: 10.1016/S0959-437X(95)90057-8  0.427
1994 Hinds PW, Dowdy SF, Eaton EN, Arnold A, Weinberg RA. Function of a human cyclin gene as an oncogene Proceedings of the National Academy of Sciences of the United States of America. 91: 709-713. PMID 8290586 DOI: 10.1073/Pnas.91.2.709  0.478
1994 Yu D, Matin A, Hinds PW, Hung MC. Transcriptional regulation of neu by RB and E1A in Rat-1 cells Cell Growth and Differentiation. 5: 431-438. PMID 8043517  0.369
1993 Dowdy SF, Hinds PW, Louie K, Reed SI, Arnold A, Weinberg RA. Physical interaction of the retinoblastoma protein with human D cyclins. Cell. 73: 499-511. PMID 8490963 DOI: 10.1016/0092-8674(93)90137-F  0.34
1992 Cobrinik D, Dowdy SF, Hinds PW, Mittnacht S, Weinberg RA. The retinoblastoma protein and the regulation of cell cycling Trends in Biochemical Sciences. 17: 312-315. PMID 1412705 DOI: 10.1016/0968-0004(92)90443-D  0.439
1992 Hinds PW, Mittnacht S, Dulic V, Arnold A, Reed SI, Weinberg RA. Regulation of retinoblastoma protein functions by ectopic expression of human cyclins Cell. 70: 993-1006. PMID 1388095 DOI: 10.1016/0092-8674(92)90249-C  0.521
1991 Mittnacht S, Hinds PW, Dowdy SF, Weinberg RA. Modulation of retinoblastoma protein activity during the cell cycle Cold Spring Harbor Symposia On Quantitative Biology. 56: 197-209. PMID 1819486 DOI: 10.1101/Sqb.1991.056.01.025  0.386
1989 Finlay CA, Hinds PW, Levine AJ. The p53 proto-oncogene can act as a suppressor of transformation Cell. 57: 1083-1093. PMID 2525423 DOI: 10.1016/0092-8674(89)90045-7  0.336
1989 Hinds P, Finlay C, Levine AJ. Mutation is required to activate the p53 gene for cooperation with the ras oncogene and transformation. Journal of Virology. 63: 739-746. DOI: 10.1128/Jvi.63.2.739-746.1989  0.332
1988 Clarke CF, Cheng K, Frey AB, Stein R, Hinds PW, Levine AJ. Purification of complexes of nuclear oncogene p53 with rat and Escherichia coli heat shock proteins: in vitro dissociation of hsc70 and dnaK from murine p53 by ATP Molecular and Cellular Biology. 8: 1206-1215. PMID 3285177 DOI: 10.1128/mcb.8.3.1206-1215.1988  0.32
1988 Finlay CA, Hinds PW, Tan TH, Eliyahu D, Oren M, Levine AJ. Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life Molecular and Cellular Biology. 8: 531-539. PMID 2832726 DOI: 10.1128/mcb.8.2.531-539.1988  0.33
1987 Hinds PW, Finlay CA, Frey AB, Levine AJ. Immunological evidence for the association of p53 with a heat shock protein, hsc70, in p53-plus-ras-transformed cell lines Molecular and Cellular Biology. 7: 2863-2869. PMID 3313006 DOI: 10.1128/mcb.7.8.2863-2869.1987  0.346
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