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Dhruv Sareen, Ph.D. - Publications

Affiliations: 
2007 University of Wisconsin, Madison, Madison, WI 
Area:
Biochemistry, Pharmacology, Oncology
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35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Coyne AN, Zaepfel BL, Hayes L, Fitchman B, Salzberg Y, Luo EC, Bowen K, Trost H, Aigner S, Rigo F, Yeo GW, Harel A, Svendsen CN, Sareen D, Rothstein JD. GC Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD. Neuron. PMID 32673563 DOI: 10.1016/J.Neuron.2020.06.027  0.332
2020 Das Sharma S, Pal R, Reddy BK, Selvaraj BT, Raj N, Samaga KK, Srinivasan DJ, Ornelas L, Sareen D, Livesey MR, Bassell GJ, Svendsen CN, Kind PC, Chandran S, Chattarji S, et al. Cortical neurons derived from human pluripotent stem cells lacking FMRP display altered spontaneous firing patterns. Molecular Autism. 11: 52. PMID 32560741 DOI: 10.1186/S13229-020-00351-4  0.343
2020 Toombs J, Panther L, Ornelas L, Liu C, Gomez E, Martín-Ibáñez R, Cox SR, Ritchie SJ, Harris SE, Taylor A, Redmond P, Russ TC, Murphy L, Cooper JD, Burr K, ... ... Sareen D, et al. Generation of twenty four induced pluripotent stem cell lines from twenty four members of the Lothian Birth Cohort 1936. Stem Cell Research. 46: 101851. PMID 32450543 DOI: 10.1016/J.Scr.2020.101851  0.323
2018 Sances S, Ho R, Vatine G, West D, Laperle A, Meyer A, Godoy M, Kay PS, Mandefro B, Hatata S, Hinojosa C, Wen N, Sareen D, Hamilton GA, Svendsen CN. Human iPSC-Derived Endothelial Cells and Microengineered Organ-Chip Enhance Neuronal Development. Stem Cell Reports. PMID 29576540 DOI: 10.1016/J.Stemcr.2018.02.012  0.373
2018 Keenan AB, Jenkins SL, Jagodnik KM, Koplev S, He E, Torre D, Wang Z, Dohlman AB, Silverstein MC, Lachmann A, Kuleshov MV, Ma'ayan A, Stathias V, Terryn R, Cooper D, ... ... Sareen D, et al. The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations. Cell Systems. 6: 13-24. PMID 29199020 DOI: 10.1016/J.Cels.2017.11.001  0.324
2017 Yucer N, Holzapfel M, Jenkins Vogel T, Lenaeus L, Ornelas L, Laury A, Sareen D, Barrett R, Karlan BY, Svendsen CN. Directed Differentiation of Human Induced Pluripotent Stem Cells into Fallopian Tube Epithelium. Scientific Reports. 7: 10741. PMID 28878359 DOI: 10.1038/S41598-017-05519-2  0.391
2017 Rajamani U, Gross AR, Ocampo C, Andres AM, Gottlieb RA, Sareen D. Endocrine disruptors induce perturbations in endoplasmic reticulum and mitochondria of human pluripotent stem cell derivatives. Nature Communications. 8: 219. PMID 28794470 DOI: 10.1038/S41467-017-00254-8  0.408
2017 Woo CJ, Maier VK, Davey R, Brennan J, Li G, Brothers J, Schwartz B, Gordo S, Kasper A, Okamoto TR, Johansson HE, Mandefro B, Sareen D, Bialek P, Chau BN, et al. Gene activation of SMN by selective disruption of lncRNA-mediated recruitment of PRC2 for the treatment of spinal muscular atrophy. Proceedings of the National Academy of Sciences of the United States of America. PMID 28193854 DOI: 10.1073/Pnas.1616521114  0.308
2017 Qu Y, Han B, Gao B, Bose S, Gong Y, Wawrowsky K, Giuliano AE, Sareen D, Cui X. Differentiation of Human Induced Pluripotent Stem Cells to Mammary-like Organoids. Stem Cell Reports. PMID 28132888 DOI: 10.1016/J.Stemcr.2016.12.023  0.403
2016 Qu Y, Zhou B, Yang W, Han B, Yu-Rice Y, Gao B, Johnson J, Svendsen CN, Freeman MR, Giuliano AE, Sareen D, Cui X. Transcriptome and proteome characterization of surface ectoderm cells differentiated from human iPSCs. Scientific Reports. 6: 32007. PMID 27550649 DOI: 10.1038/Srep32007  0.395
2016 Vazquez-Arango P, Vowles J, Browne C, Hartfield E, Fernandes HJ, Mandefro B, Sareen D, James W, Wade-Martins R, Cowley SA, Murphy S, O'Reilly D. Variant U1 snRNAs are implicated in human pluripotent stem cell maintenance and neuromuscular disease. Nucleic Acids Research. PMID 27536002 DOI: 10.1093/Nar/Gkw711  0.369
2016 Ho R, Sances S, Gowing G, Amoroso MW, O'Rourke JG, Sahabian A, Wichterle H, Baloh RH, Sareen D, Svendsen CN. ALS disrupts spinal motor neuron maturation and aging pathways within gene co-expression networks. Nature Neuroscience. PMID 27428653 DOI: 10.1038/Nn.4345  0.313
2016 Sheyn D, Ben-David S, Shapiro G, De Mel S, Bez M, Ornelas L, Sahabian A, Sareen D, Da X, Pelled G, Tawackoli W, Liu Z, Gazit D, Gazit Z. Human iPSCs Differentiate Into Functional MSCs and Repair Bone Defects. Stem Cells Translational Medicine. PMID 27400789 DOI: 10.5966/Sctm.2015-0311  0.302
2016 Milani P, Escalante-Chong R, Shelley BC, Patel-Murray NL, Xin X, Adam M, Mandefro B, Sareen D, Svendsen CN, Fraenkel E. Cell freezing protocol suitable for ATAC-Seq on motor neurons derived from human induced pluripotent stem cells. Scientific Reports. 6: 25474. PMID 27146274 DOI: 10.1038/Srep25474  0.384
2015 Kaus A, Sareen D. ALS Patient Stem Cells for Unveiling Disease Signatures of Motoneuron Susceptibility: Perspectives on the Deadly Mitochondria, ER Stress and Calcium Triad. Frontiers in Cellular Neuroscience. 9: 448. PMID 26635528 DOI: 10.3389/Fncel.2015.00448  0.346
2015 Hatada S, Subramanian A, Mandefro B, Ren S, Kim HW, Tang J, Funari V, Baloh RH, Sareen D, Arumugaswami V, Svendsen CN. Low-Dose Irradiation Enhances Gene Targeting in Human Pluripotent Stem Cells. Stem Cells Translational Medicine. PMID 26185257 DOI: 10.5966/Sctm.2015-0050  0.359
2015 Tsai Y, Lu B, Bakondi B, Girman S, Sahabian A, Sareen D, Svendsen CN, Wang S. Human iPSC-Derived Neural Progenitors Preserve Vision in an AMD-Like Model. Stem Cells (Dayton, Ohio). PMID 25869002 DOI: 10.1002/Stem.2032  0.309
2015 Mattis VB, Tom C, Akimov S, Saeedian J, Østergaard ME, Southwell AL, Doty CN, Ornelas L, Sahabian A, Lenaeus L, Mandefro B, Sareen D, Arjomand J, Hayden MR, Ross CA, et al. HD iPSC-derived neural progenitors accumulate in culture and are susceptible to BDNF withdrawal due to glutamate toxicity. Human Molecular Genetics. 24: 3257-71. PMID 25740845 DOI: 10.1093/Hmg/Ddv080  0.353
2015 Vogel T, Qu Y, Suzuki E, Drapkin R, Sareen D, Svendsen C, Cui X, Karlan B. Co-culture of human induced pluripotent stem cells (iPSCs) with human fallopian tube epithelium (FTE) induces Pax8 and CK7 expression: Initial steps in modeling fallopian tube epithelium to study serous carcinogenesis Gynecologic Oncology. 137: 206. DOI: 10.1016/J.Ygyno.2015.01.518  0.316
2014 Barrett R, Ornelas L, Yeager N, Mandefro B, Sahabian A, Lenaeus L, Targan SR, Svendsen CN, Sareen D. Reliable generation of induced pluripotent stem cells from human lymphoblastoid cell lines. Stem Cells Translational Medicine. 3: 1429-34. PMID 25298370 DOI: 10.5966/Sctm.2014-0121  0.398
2014 Sareen D, Saghizadeh M, Ornelas L, Winkler MA, Narwani K, Sahabian A, Funari VA, Tang J, Spurka L, Punj V, Maguen E, Rabinowitz YS, Svendsen CN, Ljubimov AV. Differentiation of human limbal-derived induced pluripotent stem cells into limbal-like epithelium. Stem Cells Translational Medicine. 3: 1002-12. PMID 25069777 DOI: 10.5966/Sctm.2014-0076  0.365
2014 Sareen D, Gowing G, Sahabian A, Staggenborg K, Paradis R, Avalos P, Latter J, Ornelas L, Garcia L, Svendsen CN. Human induced pluripotent stem cells are a novel source of neural progenitor cells (iNPCs) that migrate and integrate in the rodent spinal cord. The Journal of Comparative Neurology. 522: 2707-28. PMID 24610630 DOI: 10.1002/Cne.23578  0.378
2014 Mattis VB, Wakeman DR, Tom C, Dodiya HB, Yeung SY, Tran AH, Bernau K, Ornelas L, Sahabian A, Reidling J, Sareen D, Thompson LM, Kordower JH, Svendsen CN. Neonatal immune-tolerance in mice does not prevent xenograft rejection. Experimental Neurology. 254: 90-8. PMID 24440640 DOI: 10.1016/J.Expneurol.2014.01.007  0.303
2014 Barrett R, Yeager N, Rushton D, Ornelas L, Sareen D, Svendsen C, Targan S. Su1989 Generation of Functional Human Intestinal Organoids From Lymphoblastoid B-Cell Lines: Opportunity for Gene Specific Functional Assessment in IBD Gastroenterology. 146: S-516. DOI: 10.1016/S0016-5085(14)61868-0  0.351
2013 Saghizadeh M, Winkler MA, Kramerov AA, Hemmati DM, Ghiam CA, Dimitrijevich SD, Sareen D, Ornelas L, Ghiasi H, Brunken WJ, Maguen E, Rabinowitz YS, Svendsen CN, Jirsova K, Ljubimov AV. A simple alkaline method for decellularizing human amniotic membrane for cell culture. Plos One. 8: e79632. PMID 24236148 DOI: 10.1371/Journal.Pone.0079632  0.318
2013 Sareen D, O'Rourke JG, Meera P, Muhammad AK, Grant S, Simpkinson M, Bell S, Carmona S, Ornelas L, Sahabian A, Gendron T, Petrucelli L, Baughn M, Ravits J, Harms MB, et al. Targeting RNA foci in iPSC-derived motor neurons from ALS patients with a C9ORF72 repeat expansion. Science Translational Medicine. 5: 208ra149. PMID 24154603 DOI: 10.1126/Scitranslmed.3007529  0.307
2013 Ebert AD, Shelley BC, Hurley AM, Onorati M, Castiglioni V, Patitucci TN, Svendsen SP, Mattis VB, McGivern JV, Schwab AJ, Sareen D, Kim HW, Cattaneo E, Svendsen CN. EZ spheres: a stable and expandable culture system for the generation of pre-rosette multipotent stem cells from human ESCs and iPSCs. Stem Cell Research. 10: 417-27. PMID 23474892 DOI: 10.1016/J.Scr.2013.01.009  0.379
2012 Sareen D, Ebert AD, Heins BM, McGivern JV, Ornelas L, Svendsen CN. Inhibition of apoptosis blocks human motor neuron cell death in a stem cell model of spinal muscular atrophy. Plos One. 7: e39113. PMID 22723941 DOI: 10.1371/Journal.Pone.0039113  0.396
2010 Candolfi M, Xiong W, Yagiz K, Liu C, Muhammad AK, Puntel M, Foulad D, Zadmehr A, Ahlzadeh GE, Kroeger KM, Tesarfreund M, Lee S, Debinski W, Sareen D, Svendsen CN, et al. Gene therapy-mediated delivery of targeted cytotoxins for glioma therapeutics. Proceedings of the National Academy of Sciences of the United States of America. 107: 20021-6. PMID 21030678 DOI: 10.1073/Pnas.1008261107  0.334
2010 Sareen D, Svendsen CN. Stem cell biologists sure play a mean pinball. Nature Biotechnology. 28: 333-5. PMID 20379177 DOI: 10.1038/Nbt0410-333  0.335
2009 Sareen D, McMillan E, Ebert AD, Shelley BC, Johnson JA, Meisner LF, Svendsen CN. Chromosome 7 and 19 trisomy in cultured human neural progenitor cells. Plos One. 4: e7630. PMID 19898616 DOI: 10.1371/Journal.Pone.0007630  0.359
2008 van Ginkel PR, Darjatmoko SR, Sareen D, Subramanian L, Bhattacharya S, Lindstrom MJ, Albert DM, Polans AS. Resveratrol inhibits uveal melanoma tumor growth via early mitochondrial dysfunction. Investigative Ophthalmology & Visual Science. 49: 1299-306. PMID 18385041 DOI: 10.1167/Iovs.07-1233  0.649
2007 Sareen D, Darjatmoko SR, Albert DM, Polans AS. Mitochondria, calcium, and calpain are key mediators of resveratrol-induced apoptosis in breast cancer. Molecular Pharmacology. 72: 1466-75. PMID 17848600 DOI: 10.1124/Mol.107.039040  0.635
2007 van Ginkel PR, Sareen D, Subramanian L, Walker Q, Darjatmoko SR, Lindstrom MJ, Kulkarni A, Albert DM, Polans AS. Resveratrol inhibits tumor growth of human neuroblastoma and mediates apoptosis by directly targeting mitochondria. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 5162-9. PMID 17785572 DOI: 10.1158/1078-0432.Ccr-07-0347  0.67
2006 Sareen D, van Ginkel PR, Takach JC, Mohiuddin A, Darjatmoko SR, Albert DM, Polans AS. Mitochondria as the primary target of resveratrol-induced apoptosis in human retinoblastoma cells. Investigative Ophthalmology & Visual Science. 47: 3708-16. PMID 16936077 DOI: 10.1167/Iovs.06-0119  0.656
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