John Herbert Growdon, MD - Publications

Affiliations: 
Neurology Massachusetts General Hospital, Harvard University, Boston, MA, United States 
Area:
http://www.researchprofiles.collexis.com/jad/expert.asp?u_id=40
Website:
http://www.mgh.harvard.edu/neurology/doctors/doctor.aspx?id=16420

197 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Liu G, Peng J, Liao Z, Locascio JJ, Corvol JC, Zhu F, Dong X, Maple-Grødem J, Campbell MC, Elbaz A, Lesage S, Brice A, Mangone G, Growdon JH, Hung AY, et al. Genome-wide survival study identifies a novel synaptic locus and polygenic score for cognitive progression in Parkinson's disease. Nature Genetics. PMID 33958783 DOI: 10.1038/s41588-021-00847-6  0.524
2020 Huh YE, Ruby Chiang MS, Locascio JJ, Liao Z, Liu G, Choudhury K, Kuras YI, Tuncali I, Videnovic A, Hunt AL, Schwarzschild MA, Hung AY, Herrington TM, Hayes MT, Hyman BT, ... ... Growdon JH, et al. β-Glucocerebrosidase Activity in -linked Parkinson's Disease: The Type of Mutation Matters. Neurology. PMID 32540937 DOI: 10.1212/Wnl.0000000000009989  0.612
2020 Bakshi R, Macklin EA, Hung AY, Hayes MT, Hyman BT, Wills AM, Gomperts SN, Growdon JH, Ascherio A, Scherzer CR, Schwarzschild MA. Associations of Lower Caffeine Intake and Plasma Urate Levels with Idiopathic Parkinson's Disease in the Harvard Biomarkers Study. Journal of Parkinson's Disease. 10: 505-510. PMID 32250320 DOI: 10.3233/Jpd-191882  0.624
2020 Ye R, Touroutoglou A, Brickhouse M, Katz S, Growdon JH, Johnson KA, Dickerson BC, Gomperts SN. Topography of cortical thinning in the Lewy body diseases. Neuroimage. Clinical. 26: 102196. PMID 32059167 DOI: 10.1016/j.nicl.2020.102196  0.381
2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Growdon JH, et al. Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. PMID 31417202 DOI: 10.1038/s41588-019-0495-7  0.413
2019 Shirvan J, Clement N, Ye R, Katz S, Schultz A, Johnson KA, Gomez-Isla T, Frosch M, Growdon JH, Gomperts SN. Neuropathologic correlates of amyloid and dopamine transporter imaging in Lewy body disease. Neurology. PMID 31243072 DOI: 10.1212/Wnl.0000000000007855  0.307
2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Growdon JH, et al. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. 51: 414-430. PMID 30820047 DOI: 10.1038/s41588-019-0358-2  0.417
2019 Serrano-Pozo A, Growdon JH. Is Alzheimer's Disease Risk Modifiable? Journal of Alzheimer's Disease : Jad. 67: 795-819. PMID 30776012 DOI: 10.3233/Jad181028  0.374
2017 Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, ... ... Growdon JH, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics. PMID 28714976 DOI: 10.1038/Ng.3916  0.415
2017 Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, ... ... Growdon JH, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics. PMID 28714976 DOI: 10.1038/Ng.3916  0.415
2016 Marquié M, Normandin MD, Meltzer AC, Siao Tick Chong M, Andrea NV, Antón-Fernández A, Klunk WE, Mathis CA, Ikonomovic MD, Debnath M, Bien EA, Vanderburg CR, Costantino I, Makaretz S, DeVos SL, ... ... Growdon JH, et al. Pathologic correlations of [F-18]-AV-1451 imaging in non-Alzheimer tauopathies. Annals of Neurology. PMID 27997036 DOI: 10.1002/Ana.24844  0.47
2016 Gomperts SN, Locascio JJ, Makaretz SJ, Schultz A, Caso C, Vasdev N, Sperling R, Growdon JH, Dickerson BC, Johnson K. Tau Positron Emission Tomographic Imaging in the Lewy Body Diseases. Jama Neurology. PMID 27654968 DOI: 10.1001/Jamaneurol.2016.3338  0.37
2016 Boeve BF, Dickson DW, Duda JE, Ferman TJ, Galasko DR, Galvin JE, Goldman JG, Growdon JH, Hurtig HI, Kaufer DI, Kantarci K, Leverenz JB, Lippa CF, Lopez OL, McKeith IG, et al. Arguing against the proposed definition changes of PD. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 27492190 DOI: 10.1002/Mds.26721  0.35
2016 Gomperts SN, Marquie M, Locascio JJ, Bayer S, Johnson KA, Growdon JH. PET Radioligands Reveal the Basis of Dementia in Parkinson's Disease and Dementia with Lewy Bodies. Neuro-Degenerative Diseases. 16: 118-124. PMID 26655867 DOI: 10.1159/000441421  0.37
2015 Marquié M, Normandin MD, Vanderburg CR, Costantino IM, Bien EA, Rycyna LG, Klunk WE, Mathis CA, Ikonomovic MD, Debnath ML, Vasdev N, Dickerson BC, Gomperts SN, Growdon JH, Johnson KA, et al. Validating novel tau positron emission tomography tracer [F-18]-AV-1451 (T807) on postmortem brain tissue. Annals of Neurology. PMID 26344059 DOI: 10.1002/Ana.24517  0.429
2015 Hyman BT, Growdon JH, Albers MW, Buckner RL, Chhatwal J, Gomez-Isla MT, Haass C, Hudry E, Jack CR, Johnson KA, Khachaturian ZS, Kim DY, Martin JB, Nitsch RM, Rosen BR, et al. Massachusetts Alzheimer's Disease Research Center: Progress and challenges. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26297855 DOI: 10.1016/J.Jalz.2015.06.1887  0.633
2015 Locascio JJ, Eberly S, Liao Z, Liu G, Hoesing AN, Duong K, Trisini-Lipsanopoulos A, Dhima K, Hung AY, Flaherty AW, Schwarzschild MA, Hayes MT, Wills AM, Shivraj Sohur U, Mejia NI, ... ... Growdon JH, et al. Association between α-synuclein blood transcripts and early, neuroimaging-supported Parkinson's disease. Brain : a Journal of Neurology. 138: 2659-71. PMID 26220939 DOI: 10.1093/Brain/Awv202  0.645
2015 Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, ... ... Growdon JH, et al. Rarity of the Alzheimer disease-protective APP A673T variant in the United States. Jama Neurology. 72: 209-16. PMID 25531812 DOI: 10.1001/Jamaneurol.2014.2157  0.517
2015 Locascio JJ, Eberly S, Liao Z, Liu G, Hoesing AN, Duong K, Trisini-Lipsanopoulos A, Dhima K, Hung AY, Flaherty AW, Schwarzschild MA, Hayes MT, Wills AM, Shivraj Sohur U, Mejia NI, ... ... Growdon JH, et al. Association between α-synuclein blood transcripts and early, neuroimaging-supported Parkinson's disease Brain. 138: 2659-2671. DOI: 10.1093/brain/awv202  0.578
2014 Marquie M, Locascio JJ, Rentz DM, Becker JA, Hedden T, Johnson KA, Growdon JH, Gomperts SN. Striatal and extrastriatal dopamine transporter levels relate to cognition in Lewy body diseases: an (11)C altropane positron emission tomography study. Alzheimer's Research & Therapy. 6: 52. PMID 25429309 DOI: 10.1186/s13195-014-0052-7  0.329
2014 Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, ... ... Growdon JH, et al. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. Jama Neurology. 71: 1394-404. PMID 25199842 DOI: 10.1001/Jamaneurol.2014.1491  0.48
2014 Serrano-Pozo A, Qian J, Monsell SE, Blacker D, Gómez-Isla T, Betensky RA, Growdon JH, Johnson KA, Frosch MP, Sperling RA, Hyman BT. Mild to moderate Alzheimer dementia with insufficient neuropathological changes. Annals of Neurology. 75: 597-601. PMID 24585367 DOI: 10.1002/Ana.24125  0.508
2014 Growdon JH, Hyman BT. APOE genotype and brain development. Jama Neurology. 71: 7-8. PMID 24276019 DOI: 10.1001/Jamaneurol.2013.5200  0.515
2013 Santiago JA, Scherzer CR, Potashkin JA, Hyman BT, Ivinson AJ, Trisini-Lipsanopoulos A, Dhima K, Bayer S, Lockhart KC, Yi T, Liao Z, Hoesing AN, Duong K, Roderick S, Sudarsky LR, ... ... Growdon JH, et al. Specific splice variants are associated with Parkinson's disease Movement Disorders. 28: 1724-1727. PMID 24108702 DOI: 10.1002/mds.25635  0.409
2013 Ding H, Dhima K, Lockhart KC, Locascio JJ, Hoesing AN, Duong K, Trisini-Lipsanopoulos A, Hayes MT, Sohur US, Wills AM, Mollenhauer B, Flaherty AW, Hung AY, Mejia N, Khurana V, ... ... Growdon JH, et al. Unrecognized vitamin D3 deficiency is common in Parkinson disease: Harvard Biomarker Study. Neurology. 81: 1531-7. PMID 24068787 DOI: 10.1212/Wnl.0B013E3182A95818  0.604
2013 Serrano-Pozo A, Muzikansky A, Gómez-Isla T, Growdon JH, Betensky RA, Frosch MP, Hyman BT. Differential relationships of reactive astrocytes and microglia to fibrillar amyloid deposits in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 72: 462-71. PMID 23656989 DOI: 10.1097/Nen.0B013E3182933788  0.497
2013 Serrano-Pozo A, Gómez-Isla T, Growdon JH, Frosch MP, Hyman BT. A phenotypic change but not proliferation underlies glial responses in Alzheimer disease. The American Journal of Pathology. 182: 2332-44. PMID 23602650 DOI: 10.1016/J.Ajpath.2013.02.031  0.515
2013 Gomperts SN, Johnson KA, Growdon J. Reply: Beyond the limits of detection: failure of PiB imaging to capture true Aβ burden. Movement Disorders : Official Journal of the Movement Disorder Society. 28: 407. PMID 23401107 DOI: 10.1002/mds.25309  0.362
2013 Gomperts SN, Locascio JJ, Rentz D, Santarlasci A, Marquie M, Johnson KA, Growdon JH. Amyloid is linked to cognitive decline in patients with Parkinson disease without dementia. Neurology. 80: 85-91. PMID 23243071 DOI: 10.1212/WNL.0b013e31827b1a07  0.337
2013 Ziegler DA, Wonderlick JS, Ashourian P, Hansen LA, Young JC, Murphy AJ, Koppuzha CK, Growdon JH, Corkin S. Substantia nigra volume loss before basal forebrain degeneration in early Parkinson disease. Jama Neurology. 70: 241-7. PMID 23183921 DOI: 10.1001/jamaneurol.2013.597  0.324
2012 Serrano-Pozo A, Mielke ML, Muzitansky A, Gómez-Isla T, Growdon JH, Bacskai BJ, Betensky RA, Frosch MP, Hyman BT. Stable size distribution of amyloid plaques over the course of Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 71: 694-701. PMID 22805771 DOI: 10.1097/Nen.0B013E31825E77De  0.519
2012 Allen M, Zou F, Chai HS, Younkin CS, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, ... ... Growdon JH, et al. Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology. 79: 221-8. PMID 22722634 DOI: 10.1212/Wnl.0B013E3182605801  0.392
2012 Gomperts SN, Locascio JJ, Marquie M, Santarlasci AL, Rentz DM, Maye J, Johnson KA, Growdon JH. Brain amyloid and cognition in Lewy body diseases. Movement Disorders : Official Journal of the Movement Disorder Society. 27: 965-73. PMID 22693110 DOI: 10.1002/Mds.25048  0.377
2011 Ding H, Sarokhan AK, Roderick SS, Bakshi R, Maher NE, Ashourian P, Kan CG, Chang S, Santarlasci A, Swords KE, Ravina BM, Hayes MT, Sohur US, Wills AM, Flaherty AW, ... ... Growdon JH, et al. Association of SNCA with Parkinson: replication in the Harvard NeuroDiscovery Center Biomarker Study. Movement Disorders : Official Journal of the Movement Disorder Society. 26: 2283-6. PMID 21953863 DOI: 10.1002/Mds.23934  0.645
2011 Serrano-Pozo A, Mielke ML, Gómez-Isla T, Betensky RA, Growdon JH, Frosch MP, Hyman BT. Reactive glia not only associates with plaques but also parallels tangles in Alzheimer's disease. The American Journal of Pathology. 179: 1373-84. PMID 21777559 DOI: 10.1016/J.Ajpath.2011.05.047  0.528
2011 Growdon JH, Hyman BT. Plasma beta-amyloid linked to cognitive decline. Archives of Neurology. 68: 799-801. PMID 21670404 DOI: 10.1001/Archneurol.2011.114  0.439
2011 Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, ... ... Growdon JH, et al. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nature Genetics. 43: 436-41. PMID 21460841 DOI: 10.1038/Ng.801  0.432
2011 Skoglund L, Matsui T, Freeman SH, Wallin A, Blom ES, Frosch MP, Growdon JH, Hyman BT, Lannfelt L, Ingelsson M, Glaser A. Novel progranulin mutation detected in 2 patients with FTLD. Alzheimer Disease and Associated Disorders. 25: 173-8. PMID 20975516 DOI: 10.1097/Wad.0B013E3181Fbc22C  0.41
2010 Serrano-Pozo A, Vega GL, Lütjohann D, Locascio JJ, Tennis MK, Deng A, Atri A, Hyman BT, Irizarry MC, Growdon JH. Effects of simvastatin on cholesterol metabolism and Alzheimer disease biomarkers. Alzheimer Disease and Associated Disorders. 24: 220-6. PMID 20473136 DOI: 10.1097/Wad.0B013E3181D61Fea  0.518
2010 Serrano-Pozo A, William CM, Ferrer I, Uro-Coste E, Delisle MB, Maurage CA, Hock C, Nitsch RM, Masliah E, Growdon JH, Frosch MP, Hyman BT. Beneficial effect of human anti-amyloid-beta active immunization on neurite morphology and tau pathology. Brain : a Journal of Neurology. 133: 1312-27. PMID 20360050 DOI: 10.1093/Brain/Awq056  0.638
2010 Salat DH, Tuch DS, van der Kouwe AJ, Greve DN, Pappu V, Lee SY, Hevelone ND, Zaleta AK, Growdon JH, Corkin S, Fischl B, Rosas HD. White matter pathology isolates the hippocampal formation in Alzheimer's disease. Neurobiology of Aging. 31: 244-56. PMID 18455835 DOI: 10.1016/J.Neurobiolaging.2008.03.013  0.33
2009 Skoglund L, Ingvast S, Matsui T, Freeman SH, Frosch MP, Brundin R, Giedraitis V, Growdon JH, Hyman BT, Lannfelt L, Ingelsson M, Glaser A. No evidence of PGRN or MAPT gene dosage alterations in a collection of patients with frontotemporal lobar degeneration. Dementia and Geriatric Cognitive Disorders. 28: 471-5. PMID 19940479 DOI: 10.1159/000260046  0.481
2009 Dickerson BC, Bakkour A, Salat DH, Feczko E, Pacheco J, Greve DN, Grodstein F, Wright CI, Blacker D, Rosas HD, Sperling RA, Atri A, Growdon JH, Hyman BT, Morris JC, et al. The cortical signature of Alzheimer's disease: regionally specific cortical thinning relates to symptom severity in very mild to mild AD dementia and is detectable in asymptomatic amyloid-positive individuals. Cerebral Cortex (New York, N.Y. : 1991). 19: 497-510. PMID 18632739 DOI: 10.1093/Cercor/Bhn113  0.505
2008 Latourelle JC, Sun M, Lew MF, Suchowersky O, Klein C, Golbe LI, Mark MH, Growdon JH, Wooten GF, Watts RL, Guttman M, Racette BA, Perlmutter JS, Ahmed A, Shill HA, et al. The Gly2019Ser mutation in LRRK2 is not fully penetrant in familial Parkinson's disease: the GenePD study. Bmc Medicine. 6: 32. PMID 18986508 DOI: 10.1186/1741-7015-6-32  0.563
2008 Grodstein F, van Oijen M, Irizarry MC, Rosas HD, Hyman BT, Growdon JH, De Vivo I. Shorter telomeres may mark early risk of dementia: preliminary analysis of 62 participants from the nurses' health study. Plos One. 3: e1590. PMID 18795148 DOI: 10.1371/Journal.Pone.0001590  0.458
2008 Gomperts SN, Rentz DM, Moran E, Becker JA, Locascio JJ, Klunk WE, Mathis CA, Elmaleh DR, Shoup T, Fischman AJ, Hyman BT, Growdon JH, Johnson KA. Imaging amyloid deposition in Lewy body diseases. Neurology. 71: 903-10. PMID 18794492 DOI: 10.1212/01.Wnl.0000326146.60732.D6  0.53
2008 McNicoll CF, Latourelle JC, MacDonald ME, Lew MF, Suchowersky O, Klein C, Golbe LI, Mark MH, Growdon JH, Wooten GF, Watts RL, Guttman M, Racette BA, Perlmutter JS, Ahmed A, et al. Huntington CAG repeat size does not modify onset age in familial Parkinson's disease: the GenePD study. Movement Disorders : Official Journal of the Movement Disorder Society. 23: 1596-601. PMID 18649400 DOI: 10.1002/Mds.22186  0.581
2008 DeStefano AL, Latourelle J, Lew MF, Suchowersky O, Klein C, Golbe LI, Mark MH, Growdon JH, Wooten GF, Watts R, Guttman M, Racette BA, Perlmutter JS, Marlor L, Shill HA, et al. Replication of association between ELAVL4 and Parkinson disease: the GenePD study. Human Genetics. 124: 95-9. PMID 18587682 DOI: 10.1007/S00439-008-0526-4  0.573
2008 Atri A, Shaughnessy LW, Locascio JJ, Growdon JH. Long-term course and effectiveness of combination therapy in Alzheimer disease. Alzheimer Disease and Associated Disorders. 22: 209-21. PMID 18580597 DOI: 10.1097/WAD.0b013e31816653bc  0.313
2008 Locascio JJ, Fukumoto H, Yap L, Bottiglieri T, Growdon JH, Hyman BT, Irizarry MC. Plasma amyloid beta-protein and C-reactive protein in relation to the rate of progression of Alzheimer disease. Archives of Neurology. 65: 776-85. PMID 18541797 DOI: 10.1001/Archneur.65.6.776  0.499
2008 Tobin JE, Latourelle JC, Lew MF, Klein C, Suchowersky O, Shill HA, Golbe LI, Mark MH, Growdon JH, Wooten GF, Racette BA, Perlmutter JS, Watts R, Guttman M, Baker KB, et al. Haplotypes and gene expression implicate the MAPT region for Parkinson disease: the GenePD Study. Neurology. 71: 28-34. PMID 18509094 DOI: 10.1212/01.Wnl.0000304051.01650.23  0.531
2008 Freeman SH, Spires-Jones T, Hyman BT, Growdon JH, Frosch MP. TAR-DNA binding protein 43 in Pick disease. Journal of Neuropathology and Experimental Neurology. 67: 62-7. PMID 18091558 DOI: 10.1097/Nen.0B013E3181609361  0.486
2007 Irizarry MC, Yao Y, Hyman BT, Growdon JH, Praticò D. Plasma F2A isoprostane levels in Alzheimer's and Parkinson's disease. Neuro-Degenerative Diseases. 4: 403-5. PMID 17934322 DOI: 10.1159/000107699  0.52
2007 Ingelsson M, Ramasamy K, Russ C, Freeman SH, Orne J, Raju S, Matsui T, Growdon JH, Frosch MP, Ghetti B, Brown RH, Irizarry MC, Hyman BT. Increase in the relative expression of tau with four microtubule binding repeat regions in frontotemporal lobar degeneration and progressive supranuclear palsy brains. Acta Neuropathologica. 114: 471-9. PMID 17721707 DOI: 10.1007/S00401-007-0280-Z  0.479
2007 Bacskai BJ, Frosch MP, Freeman SH, Raymond SB, Augustinack JC, Johnson KA, Irizarry MC, Klunk WE, Mathis CA, Dekosky ST, Greenberg SM, Hyman BT, Growdon JH. Molecular imaging with Pittsburgh Compound B confirmed at autopsy: a case report. Archives of Neurology. 64: 431-4. PMID 17353389 DOI: 10.1001/Archneur.64.3.431  0.475
2007 Scherzer CR, Eklund AC, Morse LJ, Liao Z, Locascio JJ, Fefer D, Schwarzschild MA, Schlossmacher MG, Hauser MA, Vance JM, Sudarsky LR, Standaert DG, Growdon JH, Jensen RV, Gullans SR. Molecular markers of early Parkinson's disease based on gene expression in blood. Proceedings of the National Academy of Sciences of the United States of America. 104: 955-60. PMID 17215369 DOI: 10.1073/Pnas.0610204104  0.563
2006 Wilk JB, Tobin JE, Suchowersky O, Shill HA, Klein C, Wooten GF, Lew MF, Mark MH, Guttman M, Watts RL, Singer C, Growdon JH, Latourelle JC, Saint-Hilaire MH, DeStefano AL, et al. Herbicide exposure modifies GSTP1 haplotype association to Parkinson onset age: the GenePD Study. Neurology. 67: 2206-10. PMID 17190945 DOI: 10.1212/01.Wnl.0000249149.22407.D1  0.514
2006 Hyman BT, Growdon JH. Can the immune system fight Alzheimer disease? Nature Medicine. 12: 755-6; discussion 75. PMID 16829929 DOI: 10.1038/Nm0706-755  0.465
2006 Ingelsson M, Ramasamy K, Cantuti-Castelvetri I, Skoglund L, Matsui T, Orne J, Kowa H, Raju S, Vanderburg CR, Augustinack JC, de Silva R, Lees AJ, Lannfelt L, Growdon JH, Frosch MP, et al. No alteration in tau exon 10 alternative splicing in tangle-bearing neurons of the Alzheimer's disease brain. Acta Neuropathologica. 112: 439-49. PMID 16802167 DOI: 10.1007/S00401-006-0095-3  0.495
2006 Sun M, Latourelle JC, Wooten GF, Lew MF, Klein C, Shill HA, Golbe LI, Mark MH, Racette BA, Perlmutter JS, Parsian A, Guttman M, Nicholson G, Xu G, Wilk JB, ... ... Growdon JH, et al. Influence of heterozygosity for parkin mutation on onset age in familial Parkinson disease: the GenePD study. Archives of Neurology. 63: 826-32. PMID 16769863 DOI: 10.1001/Archneur.63.6.826  0.556
2006 Klucken J, Ingelsson M, Shin Y, Irizarry MC, Hedley-Whyte ET, Frosch M, Growdon J, McLean P, Hyman BT. Clinical and biochemical correlates of insoluble alpha-synuclein in dementia with Lewy bodies. Acta Neuropathologica. 111: 101-8. PMID 16482476 DOI: 10.1007/S00401-005-0027-7  0.65
2005 Atri A, Locascio JJ, Lin JM, Yap L, Dickerson BC, Grodstein F, Irizarry MC, Growdon JH, Greenberg SM. Prevalence and effects of lobar microhemorrhages in early-stage dementia. Neuro-Degenerative Diseases. 2: 305-12. PMID 16909013 DOI: 10.1159/000092317  0.341
2005 Irizarry MC, Gurol ME, Raju S, Diaz-Arrastia R, Locascio JJ, Tennis M, Hyman BT, Growdon JH, Greenberg SM, Bottiglieri T. Association of homocysteine with plasma amyloid beta protein in aging and neurodegenerative disease. Neurology. 65: 1402-8. PMID 16275827 DOI: 10.1212/01.Wnl.0000183063.99107.5C  0.466
2005 Karamohamed S, Golbe LI, Mark MH, Lazzarini AM, Suchowersky O, Labelle N, Guttman M, Currie LJ, Wooten GF, Stacy M, Saint-Hilaire M, Feldman RG, Liu J, Shoemaker CM, Wilk JB, ... ... Growdon J, et al. Absence of previously reported variants in the SCNA (G88C and G209A), NR4A2 (T291D and T245G) and the DJ-1 (T497C) genes in familial Parkinson's disease from the GenePD study. Movement Disorders : Official Journal of the Movement Disorder Society. 20: 1188-91. PMID 15966003 DOI: 10.1002/Mds.20515  0.54
2004 Ingelsson M, Fukumoto H, Newell KL, Growdon JH, Hedley-Whyte ET, Frosch MP, Albert MS, Hyman BT, Irizarry MC. Early Abeta accumulation and progressive synaptic loss, gliosis, and tangle formation in AD brain. Neurology. 62: 925-31. PMID 15037694 DOI: 10.1212/01.Wnl.0000115115.98960.37  0.46
2004 Lleó A, Berezovska O, Growdon JH, Hyman BT. Clinical, pathological, and biochemical spectrum of Alzheimer disease associated with PS-1 mutations. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 12: 146-56. PMID 15010344 DOI: 10.1097/00019442-200403000-00006  0.511
2004 Ingelsson M, Cantuti-Castelvetri I, Ramasamy K, Orne JD, Augustinack JC, Vanderburg CR, Growdon JH, Frosch MP, Irizarry MC, Standaert DG, Hyman BT. P3-229 Analysis of gene expression in the Alzheimer's disease brain Neurobiology of Aging. 25: S420. DOI: 10.1016/S0197-4580(04)81379-4  0.499
2003 Karamohamed S, DeStefano AL, Wilk JB, Shoemaker CM, Golbe LI, Mark MH, Lazzarini AM, Suchowersky O, Labelle N, Guttman M, Currie LJ, Wooten GF, Stacy M, Saint-Hilaire M, Feldman RG, ... ... Growdon J, et al. A haplotype at the PARK3 locus influences onset age for Parkinson's disease: the GenePD study. Neurology. 61: 1557-61. PMID 14663042 DOI: 10.1212/01.Wnl.0000095966.99430.F4  0.569
2003 Fukumoto H, Tennis M, Locascio JJ, Hyman BT, Growdon JH, Irizarry MC. Age but not diagnosis is the main predictor of plasma amyloid beta-protein levels. Archives of Neurology. 60: 958-64. PMID 12873852 DOI: 10.1001/Archneur.60.7.958  0.502
2003 Kensinger EA, Shearer DK, Locascio JJ, Growdon JH, Corkin S. Working memory in mild Alzheimer's disease and early Parkinson's disease. Neuropsychology. 17: 230-9. PMID 12803428 DOI: 10.1037/0894-4105.17.2.230  0.398
2003 Zhukareva V, Sundarraj S, Mann D, Sjogren M, Blenow K, Clark CM, McKeel DW, Goate A, Lippa CF, Vonsattel JP, Growdon JH, Trojanowski JQ, Lee VM. Selective reduction of soluble tau proteins in sporadic and familial frontotemporal dementias: an international follow-up study. Acta Neuropathologica. 105: 469-76. PMID 12677447 DOI: 10.1007/S00401-002-0668-8  0.355
2003 Locascio JJ, Corkin S, Growdon JH. Relation between clinical characteristics of Parkinson's disease and cognitive decline. Journal of Clinical and Experimental Neuropsychology. 25: 94-109. PMID 12607175 DOI: 10.1076/jcen.25.1.94.13624  0.336
2002 DeStefano AL, Lew MF, Golbe LI, Mark MH, Lazzarini AM, Guttman M, Montgomery E, Waters CH, Singer C, Watts RL, Currie LJ, Wooten GF, Maher NE, Wilk JB, Sullivan KM, ... ... Growdon JH, et al. PARK3 influences age at onset in Parkinson disease: a genome scan in the GenePD study. American Journal of Human Genetics. 70: 1089-95. PMID 11920285 DOI: 10.1086/339814  0.569
2002 Maher NE, Golbe LI, Lazzarini AM, Mark MH, Currie LJ, Wooten GF, Saint-Hilaire M, Wilk JB, Volcjak J, Maher JE, Feldman RG, Guttman M, Lew M, Waters CH, Schuman S, ... ... Growdon J, et al. Epidemiologic study of 203 sibling pairs with Parkinson's disease: the GenePD study. Neurology. 58: 79-84. PMID 11781409 DOI: 10.1212/Wnl.58.1.79  0.573
2001 DeStefano AL, Golbe LI, Mark MH, Lazzarini AM, Maher NE, Saint-Hilaire M, Feldman RG, Guttman M, Watts RL, Suchowersky O, Lafontaine AL, Labelle N, Lew MF, Waters CH, Growdon JH, et al. Genome-wide scan for Parkinson's disease: the GenePD Study. Neurology. 57: 1124-6. PMID 11571351 DOI: 10.1212/Wnl.57.6.1124  0.56
2001 Deng A, Irizarry MC, Nitsch RM, Growdon JH, Rebeck GW. Elevation of cystatin C in susceptible neurons in Alzheimer's disease. The American Journal of Pathology. 159: 1061-8. PMID 11549598 DOI: 10.1016/S0002-9440(10)61781-6  0.51
2001 Clarke RJ, Parker AJ, Kensinger EA, Growdon JH, Corkin S. Neuroanatomical correlates of semantic memory impairment seen in normal aging and early Alzheimer's disease, as measured by functional MRI Neuroimage. 13: 650. DOI: 10.1016/S1053-8119(01)91993-7  0.338
2000 Hock C, Maddalena A, Heuser I, Naber D, Oertel W, von der Kammer H, Wienrich M, Raschig A, Deng M, Growdon JH, Nitsch RM. Treatment with the selective muscarinic agonist talsaclidine decreases cerebrospinal fluid levels of total amyloid beta-peptide in patients with Alzheimer's disease. Annals of the New York Academy of Sciences. 920: 285-91. PMID 11193166 DOI: 10.1111/J.1749-6632.2000.Tb06937.X  0.568
2000 Nitsch RM, Deng M, Tennis M, Schoenfeld D, Growdon JH. The selective muscarinic M1 agonist AF102B decreases levels of total Abeta in cerebrospinal fluid of patients with Alzheimer's disease. Annals of Neurology. 48: 913-8. PMID 11117548 DOI: 10.1002/1531-8249(200012)48:6<913::Aid-Ana12>3.0.Co;2-S  0.589
2000 Finckh U, von der Kammer H, Velden J, Michel T, Andresen B, Deng A, Zhang J, Müller-Thomsen T, Zuchowski K, Menzer G, Mann U, Papassotiropoulos A, Heun R, Zurdel J, Holst F, ... ... Growdon JH, et al. Genetic association of a cystatin C gene polymorphism with late-onset Alzheimer disease. Archives of Neurology. 57: 1579-83. PMID 11074789 DOI: 10.1001/Archneur.57.11.1579  0.653
2000 Binetti G, Locascio JJ, Corkin S, Vonsattel JP, Growdon JH. Differences between Pick disease and Alzheimer disease in clinical appearance and rate of cognitive decline. Archives of Neurology. 57: 225-32. PMID 10681082 DOI: 10.1001/Archneur.57.2.225  0.364
2000 Greenberg SM, Tennis MK, Brown LB, Gomez-Isla T, Hayden DL, Schoenfeld DA, Walsh KL, Corwin C, Daffner KR, Friedman P, Meadows ME, Sperling RA, Growdon JH. Donepezil therapy in clinical practice: a randomized crossover study. Archives of Neurology. 57: 94-9. PMID 10634454 DOI: 10.1001/Archneur.57.1.94  0.326
2000 Growdon JH, Wurtman RJ, Corkin S, Nitsch RM. The molecular basis of dementia: Preface Annals of the New York Academy of Sciences. 920: xi-xii.  0.456
1999 Gasparini L, Ghidoni R, Alberici AC, Benussi L, Moratto D, Trabucchi M, Growdon JH, Nitsch RM, Binetti G. Modulation of presenilin-1 processing by nitric oxide during apoptosis induced by serum withdrawal and glucose deprivation. Annals of the New York Academy of Sciences. 893: 294-7. PMID 10672252 DOI: 10.1111/J.1749-6632.1999.Tb07840.X  0.51
1999 Newell KL, Hyman BT, Growdon JH, Hedley-Whyte ET. Application of the National Institute on Aging (NIA)-Reagan Institute criteria for the neuropathological diagnosis of Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 58: 1147-55. PMID 10560657 DOI: 10.1097/00005072-199911000-00004  0.461
1999 Gómez-Tortosa E, Newell K, Irizarry MC, Albert M, Growdon JH, Hyman BT. Clinical and quantitative pathologic correlates of dementia with Lewy bodies. Neurology. 53: 1284-91. PMID 10522886 DOI: 10.1212/Wnl.53.6.1284  0.496
1999 Alberici A, Moratto D, Benussi L, Gasparini L, Ghidoni R, Gatta LB, Finazzi D, Frisoni GB, Trabucchi M, Growdon JH, Nitsch RM, Binetti G. Presenilin 1 protein directly interacts with Bcl-2. The Journal of Biological Chemistry. 274: 30764-9. PMID 10521466 DOI: 10.1074/Jbc.274.43.30764  0.51
1999 Irizarry MC, Ghaemi SN, Lee-Cherry ER, Gomez-Isla T, Binetti G, Hyman BT, Growdon JH. Risperidone treatment of behavioral disturbances in outpatients with dementia. The Journal of Neuropsychiatry and Clinical Neurosciences. 11: 336-42. PMID 10440009 DOI: 10.1176/Jnp.11.3.336  0.431
1998 Wurtman J, Wurtman R, Mark S, Tsay R, Gilbert W, Growdon J. d-Fenfluramine selectively suppresses carbohydrate snacking by obese subjects. The International Journal of Eating Disorders. 4: 89-99. PMID 11540865 DOI: 10.1002/1098-108X(198502)4:1<89::AID-EAT2260040110>3.0.CO;2-D  0.414
1998 Liao A, Nitsch RM, Greenberg SM, Finckh U, Blacker D, Albert M, Rebeck GW, Gomez-Isla T, Clatworthy A, Binetti G, Hock C, Mueller-Thomsen T, Mann U, Zuchowski K, Beisiegel U, ... ... Growdon JH, et al. Genetic association of an alpha2-macroglobulin (Val1000lle) polymorphism and Alzheimer's disease. Human Molecular Genetics. 7: 1953-6. PMID 9811940 DOI: 10.1093/Hmg/7.12.1953  0.596
1998 Trojanowski JQ, Growdon JH. A new consensus report on biomarkers for the early antemortem diagnosis of Alzheimer disease: current status, relevance to drug discovery, and recommendations for future research. Journal of Neuropathology and Experimental Neurology. 57: 643-4. PMID 9630242 DOI: 10.1097/00005072-199806000-00010  0.304
1998 Silver M, Newell K, Hyman B, Growdon J, Hedley-Whyte ET, Perls T. Unraveling the mystery of cognitive changes in old age: correlation of neuropsychological evaluation with neuropathological findings in the extreme old. International Psychogeriatrics / Ipa. 10: 25-41. PMID 9629522 DOI: 10.1017/S1041610298005122  0.516
1998 Growdon JH, Kieburtz K, McDermott MP, Panisset M, Friedman JH. Levodopa improves motor function without impairing cognition in mild non-demented Parkinson's disease patients. Parkinson Study Group. Neurology. 50: 1327-31. PMID 9595982 DOI: 10.1212/Wnl.50.5.1327  0.309
1998 Hock C, Drasch G, Golombowski S, Müller-Spahn F, Willershausen-Zönnchen B, Schwarz P, Hock U, Growdon JH, Nitsch RM. Increased blood mercury levels in patients with Alzheimer's disease. Journal of Neural Transmission (Vienna, Austria : 1996). 105: 59-68. PMID 9588761 DOI: 10.1007/s007020050038  0.51
1998 Nitsch RM, Kim C, Growdon JH. Vasopressin and bradykinin regulate secretory processing of the amyloid protein precursor of Alzheimer's disease. Neurochemical Research. 23: 807-14. PMID 9566621 DOI: 10.1023/A:1022423813362  0.51
1998 Davies P, Resnick J, Resnick B, Gilman S, Growdon JH, Khachaturian ZS, Radebaugh TS, Roses AD, Selkoe DJ, Trojanowski JQ, Blass JP, Gibson GE, Sheu KFR, Blennow K, Delacourte A, et al. Consensus report of the working group on: 'Molecular and biochemical markers of Alzheimer's disease' Neurobiology of Aging. 19: 109-116. PMID 9558143 DOI: 10.1016/S0197-4580(98)00022-0  0.526
1998 Hock C, Golombowski S, Müller-Spahn F, Naser W, Beyreuther K, Mönning U, Schenk D, Vigo-Pelfrey C, Bush AM, Moir R, Tanzi RE, Growdon JH, Nitsch RM. Cerebrospinal fluid levels of amyloid precursor protein and amyloid beta-peptide in Alzheimer's disease and major depression - inverse correlation with dementia severity. European Neurology. 39: 111-8. PMID 9520072 DOI: 10.1159/000007917  0.587
1998 Rebeck GW, Alonzo NC, Berezovska O, Harr SD, Knowles RB, Growdon JH, Hyman BT, Mendez AJ. Structure and functions of human cerebrospinal fluid lipoproteins from individuals of different APOE genotypes. Experimental Neurology. 149: 175-82. PMID 9454626 DOI: 10.1006/Exnr.1997.6710  0.434
1997 Growdon JH, Graefe K, Tennis M, Hayden D, Schoenfeld D, Wray SH. Pupil dilation to tropicamide is not specific for Alzheimer disease. Archives of Neurology. 54: 841-4. PMID 9236572 DOI: 10.1001/Archneur.1997.00550190031011  0.348
1997 Nitsch RM, Deng A, Wurtman RJ, Growdon JH. Metabotropic glutamate receptor subtype mGluR1alpha stimulates the secretion of the amyloid beta-protein precursor ectodomain. Journal of Neurochemistry. 69: 704-12. PMID 9231730 DOI: 10.1046/j.1471-4159.1997.69020704.x  0.61
1997 Gómez-Isla T, Wasco W, Pettingell WP, Gurubhagavatula S, Schmidt SD, Jondro PD, McNamara M, Rodes LA, DiBlasi T, Growdon WB, Seubert P, Schenk D, Growdon JH, Hyman BT, Tanzi RE. A novel presenilin-1 mutation: increased beta-amyloid and neurofibrillary changes. Annals of Neurology. 41: 809-13. PMID 9189043 DOI: 10.1002/Ana.410410618  0.47
1997 Scott WK, Yamaoka LH, Locke PA, Rosi BL, Gaskell PC, Saunders AM, Conneally PM, Small GW, Farrer LA, Growdon JH, Roses AD, Pericak-Vance MA, Haines JL. No association or linkage between an intronic polymorphism of presenilin-1 and sporadic or late-onset familial Alzheimer disease. Genetic Epidemiology. 14: 307-15. PMID 9181359 DOI: 10.1002/(Sici)1098-2272(1997)14:3<307::Aid-Gepi8>3.0.Co;2-1  0.354
1997 Postle BR, Jonides J, Smith EE, Corkin S, Growdon JH. Spatial, but not object, delayed response is impaired in early Parkinson's disease. Neuropsychology. 11: 171-9. PMID 9110324 DOI: 10.1037/0894-4105.11.2.171  0.301
1997 Gómez-Isla T, Hollister R, West H, Mui S, Growdon JH, Petersen RC, Parisi JE, Hyman BT. Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease. Annals of Neurology. 41: 17-24. PMID 9005861 DOI: 10.1002/Ana.410410106  0.485
1997 Newell K, Hyman B, Growdon J, Hedlev-Whyte ET. EVALUATION OF NIA-REAGAN INSTITUTE CRITERIA FOR THE NEUROPATHOLOGICAL DIAGNOSIS OF ALZHEIMER DISEASE Journal of Neuropathology and Experimental Neurology. 56: 593. DOI: 10.1097/00005072-199705000-00100  0.49
1996 Postle BR, Corkin S, Growdon JH. Intact implicit memory for novel patterns in Alzheimer's disease. Learning & Memory (Cold Spring Harbor, N.Y.). 3: 305-12. PMID 10456100 DOI: 10.1101/Lm.3.4.305  0.322
1996 Haines JL, Pritchard ML, Saunders AM, Schildkraut JM, Growdon JH, Gaskell PC, Farrer LA, Auerbach SA, Gusella JF, Locke PA, Rosi BL, Yamaoka L, Small GW, Conneally PM, Roses AD, et al. No association between alpha 1-antichymotrypsin and familial Alzheimer's disease. Annals of the New York Academy of Sciences. 802: 35-41. PMID 8993482 DOI: 10.1111/J.1749-6632.1996.Tb32596.X  0.38
1996 Hyman BT, Gomez-Isla T, Rebeck GW, Briggs M, Chung H, West HL, Greenberg S, Mui S, Nichols S, Wallace R, Growdon JH. Epidemiological, clinical, and neuropathological study of apolipoprotein E genotype in Alzheimer's disease. Annals of the New York Academy of Sciences. 802: 1-5. PMID 8993478 DOI: 10.1111/J.1749-6632.1996.Tb32592.X  0.503
1996 Growdon JH, Locascio JJ, Corkin S, Gomez-Isla T, Hyman BT. Apolipoprotein E genotype does not influence rates of cognitive decline in Alzheimer's disease. Neurology. 47: 444-8. PMID 8757018 DOI: 10.1212/Wnl.47.2.444  0.515
1996 Gómez-Isla T, Price JL, McKeel DW, Morris JC, Growdon JH, Hyman BT. Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 4491-500. PMID 8699259 DOI: 10.1523/Jneurosci.16-14-04491.1996  0.463
1996 Hyman BT, Hedley-Whyte ET, Rebeck GW, Vonsattel JP, West HL, Growdon JH. Apolipoprotein E epsilon4/4 in a neuropathologically normal very elderly individual. Archives of Neurology. 53: 215. PMID 8651872 DOI: 10.1001/Archneur.1996.00550030017010  0.514
1996 Nitsch RM, Deng M, Growdon JH, Wurtman RJ. Serotonin 5-HT2a and 5-HT2c receptors stimulate amyloid precursor protein ectodomain secretion. The Journal of Biological Chemistry. 271: 4188-94. PMID 8626761 DOI: 10.1074/jbc.271.8.4188  0.638
1996 Nitsch RM, Wurtman RJ, Growdon JH. Regulation of APP processing. Potential for the therapeutical reduction of brain amyloid burden. Annals of the New York Academy of Sciences. 777: 175-82. PMID 8624081 DOI: 10.1111/j.1749-6632.1996.tb34416.x  0.658
1996 Hyman BT, Gomez-Isla T, West H, Briggs M, Chung H, Growdon JH, Rebeck GW. Clinical and neuropathological correlates of apolipoprotein E genotype in Alzheimer's disease. Window on molecular epidemiology. Annals of the New York Academy of Sciences. 777: 158-65. PMID 8624079 DOI: 10.1111/J.1749-6632.1996.Tb34414.X  0.495
1996 Gomez-Isla T, West HL, Rebeck GW, Harr SD, Growdon JH, Locascio JJ, Perls TT, Lipsitz LA, Hyman BT. Clinical and pathological correlates of apolipoprotein E epsilon 4 in Alzheimer's disease. Annals of Neurology. 39: 62-70. PMID 8572669 DOI: 10.1002/Ana.410390110  0.519
1996 Gomez-Isla T, Hollister R, West H, Mui S, Growdon JH, Pelersen RC, Parisi JE, Hyman BT. NEURONAL LOSS IN ALZHEIMERʼS DISEASE Journal of Neuropathology and Experimental Neurology. 55: 617. DOI: 10.1097/00005072-199605000-00058  0.436
1995 Nitsch RM, Wurtman RJ, Growdon JH. Regulation of proteolytic processing of the amyloid beta-protein precursor by first messengers. A novel potential approach for the treatment of Alzheimer's disease. Arzneimittel-Forschung. 45: 435-8. PMID 7763340  0.451
1995 Cronin-Golomb A, Corkin S, Growdon JH. Visual dysfunction predicts cognitive deficits in Alzheimer's disease. Optometry and Vision Science : Official Publication of the American Academy of Optometry. 72: 168-76. PMID 7609939 DOI: 10.1097/00006324-199503000-00004  0.314
1995 Mendola JD, Cronin-Golomb A, Corkin S, Growdon JH. Prevalence of visual deficits in Alzheimer's disease. Optometry and Vision Science : Official Publication of the American Academy of Optometry. 72: 155-67. PMID 7609938 DOI: 10.1097/00006324-199503000-00003  0.353
1995 Locascio JJ, Growdon JH, Corkin S. Cognitive test performance in detecting, staging, and tracking Alzheimer's disease. Archives of Neurology. 52: 1087-99. PMID 7487561 DOI: 10.1001/archneur.1995.00540350081020  0.379
1995 Farrer LA, Cupples LA, Van Duijn CM, Kurz A, Zimmer R, Müller U, Green RC, Clarke V, Shoffner J, Wallace DC, Chui H, Flanagan SD, Duara R, St. George-Hyslop P, Auerbach SA, ... ... Growdon JH, et al. Apolipoprotein E genotype in patients with Alzheimer's disease: Implications for the risk of dementia among relatives Annals of Neurology. 38: 797-808. PMID 7486872 DOI: 10.1002/Ana.410380515  0.349
1994 Keane MM, Gabrieli JD, Growdon JH, Corkin S. Priming in perceptual identification of pseudowords is normal in Alzheimer's disease. Neuropsychologia. 32: 343-56. PMID 8202228 DOI: 10.1016/0028-3932(94)90136-8  0.343
1994 Cronin-Golomb A, Corkin S, Growdon JH. Impaired problem solving in Parkinson's disease: impact of a set-shifting deficit. Neuropsychologia. 32: 579-93. PMID 8084416 DOI: 10.1016/0028-3932(94)90146-5  0.302
1994 Gabrieli JD, Keane MM, Stanger BZ, Kjelgaard MM, Corkin S, Growdon JH. Dissociations among structural-perceptual, lexical-semantic, and event-fact memory systems in Alzheimer, amnesic, and normal subjects. Cortex; a Journal Devoted to the Study of the Nervous System and Behavior. 30: 75-103. PMID 8004991 DOI: 10.1016/S0010-9452(13)80325-5  0.349
1994 Kurylo DD, Corkin S, Dolan RP, Rizzo JF, Parker SW, Growdon JH. Broad-band visual capacities are not selectively impaired in Alzheimer's disease. Neurobiology of Aging. 15: 305-11. PMID 7936054 DOI: 10.1016/0197-4580(94)90025-6  0.318
1994 Nitsch RM, Growdon JH. Role of neurotransmission in the regulation of amyloid beta-protein precursor processing. Biochemical Pharmacology. 47: 1275-84. PMID 7910457 DOI: 10.1016/0006-2952(94)90325-5  0.51
1994 Nitsch RM, Slack BE, Farber SA, Schulz JG, Deng M, Kim C, Borghesani PR, Korver W, Wurtman RJ, Growdon JH. Regulation of proteolytic processing of the amyloid beta-protein precursor of Alzheimer's disease in transfected cell lines and in brain slices. Journal of Neural Transmission. Supplementum. 44: 21-7. PMID 7897393 DOI: 10.1007/978-3-7091-9350-1_2  0.783
1994 Farber S, Nitsch R, Growdon J, Wurtman R. 24. A novel approach to study the regulated release of secretory proteins from brain slices Journal of Neuroscience Methods. 52: A11-A12. DOI: 10.1016/0165-0270(94)90084-1  0.707
1993 Nitsch RM, Farber SA, Growdon JH, Wurtman RJ. Release of amyloid beta-protein precursor derivatives by electrical depolarization of rat hippocampal slices. Proceedings of the National Academy of Sciences of the United States of America. 90: 5191-3. PMID 8506366 DOI: 10.1073/PNAS.90.11.5191  0.725
1993 Kurylo DD, Corkin S, Allard T, Zatorre RJ, Growdon JH. Auditory function in Alzheimer's disease. Neurology. 43: 1893-9. PMID 8413944 DOI: 10.1212/Wnl.43.10.1893  0.329
1993 Nitsch RM, Blusztajn JK, Doyle FM, Robitaille Y, Wurtman RJ, Growdon JH, Kish SJ. Phospholipid metabolite levels are altered in cerebral cortex of patients with dominantly inherited olivopontocerebellar atrophy. Neuroscience Letters. 161: 191-4. PMID 8272265 DOI: 10.1016/0304-3940(93)90291-R  0.617
1993 Cronin-Golomb A, Sugiura R, Corkin S, Growdon JH. Incomplete achromatopsia in Alzheimer's disease. Neurobiology of Aging. 14: 471-7. PMID 8247229 DOI: 10.1016/0197-4580(93)90105-K  0.356
1993 Nitsch RM, Slack BE, Farber SA, Borghesani PR, Schulz JG, Kim C, Felder CC, Growdon JH, Wurtman RJ. Receptor-coupled amyloid precursor protein processing. Annals of the New York Academy of Sciences. 695: 122-7. PMID 8239269 DOI: 10.1111/J.1749-6632.1993.Tb23039.X  0.772
1993 Hung AY, Haass C, Nitsch RM, Qiu WQ, Citron M, Wurtman RJ, Growdon JH, Selkoe DJ. Activation of protein kinase C inhibits cellular production of the amyloid beta-protein. The Journal of Biological Chemistry. 268: 22959-62. PMID 8226807  0.451
1993 Gabrieli JD, Corkin S, Mickel SF, Growdon JH. Intact acquisition and long-term retention of mirror-tracing skill in Alzheimer's disease and in global amnesia. Behavioral Neuroscience. 107: 899-910. PMID 8136066 DOI: 10.1037/0735-7044.107.6.899  0.365
1993 Borgaonkar DS, Schmidt LC, Martin SE, Kanzer MD, Edelsohn L, Growdon J, Farrer LA. Linkage of late-onset Alzheimer's disease with apolipoprotein E type 4 on chromosome 19. Lancet. 342: 625. PMID 8102761 DOI: 10.1016/0140-6736(93)91458-X  0.331
1992 Rizzo JF, Cronin-Golomb A, Growdon JH, Corkin S, Rosen TJ, Sandberg MA, Chiappa KH, Lessell S. Retinocalcarine function in Alzheimer's disease. A clinical and electrophysiological study. Archives of Neurology. 49: 93-101. PMID 1728270 DOI: 10.1001/Archneur.1992.00530250097023  0.35
1992 Arriagada PV, Growdon JH, Hedley-Whyte ET, Hyman BT. Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease. Neurology. 42: 631-9. PMID 1549228 DOI: 10.1212/Wnl.42.3.631  0.498
1992 Nitsch RM, Slack BE, Wurtman RJ, Growdon JH. Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors. Science (New York, N.Y.). 258: 304-7. PMID 1411529 DOI: 10.1126/SCIENCE.1411529  0.732
1992 Cronin-Golomb A, Keane MM, Kokodis A, Corkin S, Growdon JH. Category knowledge in Alzheimer's disease: normal organization and a general retrieval deficit. Psychology and Aging. 7: 359-66. PMID 1388856 DOI: 10.1037//0882-7974.7.3.359  0.355
1992 Nitsch RM, Blusztajn JK, Pittas AG, Slack BE, Growdon JH, Wurtman RJ. Evidence for a membrane defect in Alzheimer disease brain. Proceedings of the National Academy of Sciences of the United States of America. 89: 1671-5. PMID 1311847 DOI: 10.1073/Pnas.89.5.1671  0.749
1992 Huff EJ, Growdon JH, Corkin S. Deterioration on the Blessed Information-Memory-Concentration Test in Alzheimer's disease. Psychiatry Research. 44: 167-8. PMID 1301042 DOI: 10.1016/0165-1781(92)90050-D  0.318
1992 Nitsch RM, Slack BE, Wurtman RJ, Growdon JH. SECRETION OF ALZHEIMER AMYLOID PRECURSOR PROTEIN IS STIMULATED BY MUSCARINIC RECEPTOR ACTIVATION. Clinical Neuropharmacology. 15: 464B. DOI: 10.1097/00002826-199202001-00902  0.629
1991 Keane MM, Gabrieli JD, Fennema AC, Growdon JH, Corkin S. Evidence for a dissociation between perceptual and conceptual priming in Alzheimer's disease. Behavioral Neuroscience. 105: 326-42. PMID 2043276 DOI: 10.1037/0735-7044.105.2.326  0.34
1991 Farrer LA, Cupples LA, Connor L, Wolf PA, Growdon JH. Association of decreased paternal age and late-onset Alzheimer's disease. An example of genetic imprinting? Archives of Neurology. 48: 599-604. PMID 2039382 DOI: 10.1001/archneur.1991.00530180051017  0.377
1991 Cronin-Golomb A, Corkin S, Rizzo JF, Cohen J, Growdon JH, Banks KS. Visual dysfunction in Alzheimer's disease: relation to normal aging. Annals of Neurology. 29: 41-52. PMID 1996878 DOI: 10.1002/Ana.410290110  0.34
1991 Berry EM, Growdon JH, Wurtman JJ, Caballero B, Wurtman RJ. A balanced carbohydrate: protein diet in the management of Parkinson's disease. Neurology. 41: 1295-7. PMID 1866021 DOI: 10.1212/WNL.41.8.1295  0.63
1991 Cronin-Golomb A, Rizzo JF, Corkin S, Growdon JH. Visual function in Alzheimer's disease and normal aging. Annals of the New York Academy of Sciences. 640: 28-35. PMID 1776752 DOI: 10.1111/J.1749-6632.1991.Tb00186.X  0.354
1991 Growdon JH, Nader TM, Schoenfeld J, Wurtman RJ. L-threonine in the treatment of spasticity. Clinical Neuropharmacology. 14: 403-12. PMID 1742749 DOI: 10.1097/00002826-199110000-00003  0.354
1991 Nitsch R, Pittas A, Blusztajn JK, Slack BE, Growdon JH, Wurtman RJ. Alterations of phospholipid metabolites in postmortem brain from patients with Alzheimer's disease. Annals of the New York Academy of Sciences. 640: 110-3. PMID 1663712 DOI: 10.1111/J.1749-6632.1991.Tb00200.X  0.752
1990 Wurtman RJ, Blusztajn JK, Ulus IH, Coviella IL, Buyukuysal RL, Growdon JH, Slack BE. Choline metabolism in cholinergic neurons: implications for the pathogenesis of neurodegenerative diseases. Advances in Neurology. 51: 117-25. PMID 2403709  0.686
1990 Blusztajn JK, Lopez Gonzalez-Coviella I, Logue M, Growdon JH, Wurtman RJ. Levels of phospholipid catabolic intermediates, glycerophosphocholine and glycerophosphoethanolamine, are elevated in brains of Alzheimer's disease but not of Down's syndrome patients. Brain Research. 536: 240-4. PMID 2150771 DOI: 10.1016/0006-8993(90)90030-F  0.531
1989 de la Monte SM, Wells SE, Hedley-Whyte T, Growdon JH. Neuropathological distinction between Parkinson's dementia and Parkinson's plus Alzheimer's disease. Annals of Neurology. 26: 309-20. PMID 2802531 DOI: 10.1002/ana.410260302  0.393
1989 Farrer LA, O'Sullivan DM, Cupples LA, Growdon JH, Myers RH. Assessment of genetic risk for Alzheimer's disease among first-degree relatives. Annals of Neurology. 25: 485-93. PMID 2774490 DOI: 10.1002/Ana.410250511  0.375
1989 Freed DM, Corkin S, Growdon JH, Nissen MJ. Selective attention in Alzheimer's disease: characterizing cognitive subgroups of patients. Neuropsychologia. 27: 325-39. PMID 2710323 DOI: 10.1016/0028-3932(89)90022-5  0.32
1989 Phelps CH, Gage FH, Growdon JH, Hefti F, Harbaugh R, Johnston MV, Khachaturian ZS, Mobley WC, Price DL, Raskind M. Potential use of nerve growth factor to treat Alzheimer's disease. Neurobiology of Aging. 10: 205-7. PMID 2657468 DOI: 10.1016/0197-4580(89)90032-8  0.521
1989 Sullivan EV, Sagar HJ, Gabrieli JD, Corkin S, Growdon JH. Different cognitive profiles on standard behavioral tests in Parkinson's disease and Alzheimer's disease. Journal of Clinical and Experimental Neuropsychology. 11: 799-820. PMID 2592525 DOI: 10.1080/01688638908400937  0.384
1989 Wurtman RJ, Ulus IH, Blusztajn JK, Lopez-Coviella I, Agut J, Ortiz JA, Logue M, Mauron C, Growdon JH. Choline levels, the regulation of acetylcholine and phosphatidylcholine synthesis, and Alzheimer's disease Journal of Neural Transmission - Parkinson's Disease and Dementia Section. 1: 15. DOI: 10.1007/BF02312196  0.664
1988 Sagar HJ, Sullivan EV, Gabrieli JD, Corkin S, Growdon JH. Temporal ordering and short-term memory deficits in Parkinson's disease. Brain : a Journal of Neurology. 111: 525-39. PMID 3382911 DOI: 10.1093/Brain/111.3.525  0.352
1988 Sagar HJ, Cohen NJ, Sullivan EV, Corkin S, Growdon JH. Remote memory function in Alzheimer's disease and Parkinson's disease. Brain : a Journal of Neurology. 111: 185-206. PMID 3365547 DOI: 10.1093/Brain/111.1.185  0.342
1988 Freed DM, Corkin S, Growdon JH, Nissen MJ. Selective attention in Alzheimer's disease: CSF correlates of behavioral impairments. Neuropsychologia. 26: 895-902. PMID 2461537 DOI: 10.1016/0028-3932(88)90057-7  0.34
1987 Huff FJ, Growdon JH, Corkin S, Rosen TJ. Age at onset and rate of progression of Alzheimer's disease. Journal of the American Geriatrics Society. 35: 27-30. PMID 3794143 DOI: 10.1111/J.1532-5415.1987.Tb01315.X  0.362
1987 St George-Hyslop PH, Tanzi RE, Polinsky RJ, Neve RL, Pollen D, Drachman D, Growdon J, Cupples LA, Nee L, Myers RH. Absence of duplication of chromosome 21 genes in familial and sporadic Alzheimer's disease. Science (New York, N.Y.). 238: 664-6. PMID 2890206 DOI: 10.1126/Science.2890206  0.367
1986 Mazurek MF, Growdon JH, Beal MF, Martin JB. CSF vasopressin concentration is reduced in Alzheimer's disease. Neurology. 36: 1133-7. PMID 3736884 DOI: 10.1212/Wnl.36.8.1133  0.352
1986 Huff FJ, Corkin S, Growdon JH. Semantic impairment and anomia in Alzheimer's disease. Brain and Language. 28: 235-49. PMID 3730816 DOI: 10.1016/0093-934X(86)90103-3  0.339
1986 Huff FJ, Maire JC, Growdon JH, Corkin S, Wurtman RJ. Cholinesterases in cerebrospinal fluid. Correlations with clinical measures in Alzheimer's disease. Journal of the Neurological Sciences. 72: 121-9. PMID 3711929 DOI: 10.1016/0022-510X(86)90001-8  0.674
1986 Growdon JH, Corkin S, Huff FJ, Rosen TJ. Piracetam combined with lecithin in the treatment of Alzheimer's disease. Neurobiology of Aging. 7: 269-76. PMID 3528889 DOI: 10.1016/0197-4580(86)90007-2  0.341
1986 Beal MF, Growdon JH, Mazurek MF, Martin JB. CSF somatostatin-like immunoreactivity in dementia. Neurology. 36: 294-7. PMID 2868429 DOI: 10.1212/Wnl.36.2.294  0.407
1986 Sullivan EV, Corkin S, Growdon JH. Verbal and Nonverbal Short-Term Memory in Patients With Alzheimer's Disease and in Healthy Elderly Subjects Developmental Neuropsychology. 2: 387-400. DOI: 10.1080/87565648609540356  0.35
1985 Lieberman HR, Corkin S, Spring BJ, Wurtman RJ, Growdon JH. The effects of dietary neurotransmitter precursors on human behavior. The American Journal of Clinical Nutrition. 42: 366-70. PMID 4025206 DOI: 10.1093/ajcn/42.2.366  0.549
1985 Logue MP, Growdon JH, Coviella IL, Wurtman RJ. Differential effects of DSP-4 administration on regional brain norepinephrine turnover in rats. Life Sciences. 37: 403-9. PMID 4021721 DOI: 10.1016/0024-3205(85)90401-1  0.463
1985 Gibson CJ, Logue M, Growdon JH. CSF monoamine metabolite levels in Alzheimer's and Parkinson's disease. Archives of Neurology. 42: 489-92. PMID 2581531 DOI: 10.1001/archneur.1985.04060050091016  0.573
1985 Wurtman J, Wurtman R, Mark S, Tsay R, Gilbert W, Growdon J. d-Fenfluramine selectively suppresses carbohydrate snacking by obese subjects Journal of Clinical Psychopharmacology. 5: 309. DOI: 10.1097/00004714-198510000-00023  0.306
1984 Lieberman HR, Corkin S, Spring BJ, Garfield GS, Growdon JH, Wurtman RJ. The effects of tryptophan and tyrosine on human mood and performance. Psychopharmacology Bulletin. 20: 595-8. PMID 6473667  0.328
1984 Zubenko GS, Cohen BM, Growdon J, Corkin S. Cell membrane abnormality in Alzheimer's disease. Lancet (London, England). 2: 235. PMID 6146798 DOI: 10.1016/S0140-6736(84)90528-2  0.343
1983 Corkin S, Growdon JH, Rasmussen SL. Parental age as a risk factor in Alzheimer's disease. Annals of Neurology. 13: 674-6. PMID 6881929 DOI: 10.1002/ana.410130618  0.351
1982 Canter NL, Hallett M, Growdon JH. Lecithin does not affect EEG spectral analysis or P300 in Alzheimer disease. Neurology. 32: 1260-6. PMID 6890160 DOI: 10.1212/Wnl.32.11.1260  0.328
1982 Lieberman HR, Corkin S, Spring BJ, Growdon JH, Wurtman RJ. Mood, performance, and pain sensitivity: changes induced by food constituents. Journal of Psychiatric Research. 17: 135-45. PMID 6764930 DOI: 10.1016/0022-3956(82)90015-2  0.529
1982 Growdon JH, Melamed E, Logue M, Hefti F, Wurtman RJ. Effects of oral L-tyrosine administration on CSF tyrosine and homovanillic acid levels in patients with Parkinson's disease. Life Sciences. 30: 827-32. PMID 6175872 DOI: 10.1016/0024-3205(82)90596-3  0.669
1982 Reinstein D, Corkin S, Growdon JH, Wurtman RJ, Zeisel SH. The second meeting of the international study group on the pharmacology of memory disorders associated with aging (ISG) Neuropsychologia. 20: 225-226. DOI: 10.1016/0028-3932(82)90015-X  0.559
1981 Zeisel S, Reinstein D, Corkin S, Growdon J, Wurtman R. Cholinergic neurones and memory. Nature. 293: 187-8. PMID 7278975 DOI: 10.1038/293187a0  0.556
1981 Wurtman JJ, Wurtman RJ, Growdon JH, Henry P, Lipscomb A, Zeisel SH. Carbohydrate craving in obese people: Suppression by treatments affecting serotoninergic transmission International Journal of Eating Disorders. 1: 2-15. DOI: 10.1002/1098-108X(198123)1:1<2::AID-EAT2260010102>3.0.CO;2-Q  0.43
1980 Gelenberg AJ, Wojcik JD, Growdon JH, Sved AF, Wurtman RJ. Tyrosine for the treatment of depression. The American Journal of Psychiatry. 137: 622-3. PMID 7369415 DOI: 10.1176/AJP.137.5.622  0.565
1980 Zeisel SH, Growdon JH, Wurtman RJ, Magil SG, Logue M. Normal plasma choline responses to ingested lecithin. Neurology. 30: 1226-9. PMID 7191517 DOI: 10.1212/WNL.30.11.1226  0.564
1980 Melamed E, Glaeser B, Growdon JH, Wurtman RJ. Plasma tyrosine in normal humans: effects of oral tyrosine and protein-containing meals. Journal of Neural Transmission. 47: 299-306. PMID 7190187 DOI: 10.1007/BF01247323  0.575
1980 Zeisel SH, Gelenberg AJ, Growdon JH, Wurtman RJ. Use of choline and lecithin in the treatment of tardive dyskinesia. Advances in Biochemical Psychopharmacology. 24: 463-70. PMID 6996444  0.426
1979 Glaeser BS, Melamed E, Growdon JH, Wurtman RJ. Elevation of plasma tyrosine after a single oral dose of L-tyrosine. Life Sciences. 25: 265-71. PMID 481129 DOI: 10.1016/0024-3205(79)90294-7  0.544
1979 Growdon JH, Wurtman RJ. Dietary influences on the synthesis of neurotransmitters in the brain. Nutrition Reviews. 37: 129-36. PMID 40170 DOI: 10.1111/J.1753-4887.1979.TB06649.X  0.354
1978 Hirsch MJ, Growdon JH, Wurtman RJ. Relations between dietary choline or lecithin intake, serum choline levels, and various metabolic indices. Metabolism: Clinical and Experimental. 27: 953-60. PMID 672614 DOI: 10.1016/0026-0495(78)90139-7  0.469
1978 Sahakian BJ, Growdon JH, Millington WR, Barr JK, Wurtman RJ. The effects of cholinergic agonists on apomorphine-induced stereotyped behavior in the rat. Communications in Psychopharmacology. 2: 255-62. PMID 568059  0.382
1978 Wurtman RJ, Growdon JH. Dietary enhancement of CNS neurotransmitters. Hospital Practice. 13: 71-7. PMID 147851 DOI: 10.1080/21548331.1978.11707296  0.481
1977 Growdon JH, Hirsch MJ, Wurtman RJ, Wiener W. Oral choline administration to patients with tardive dyskinesia. The New England Journal of Medicine. 297: 524-7. PMID 887103 DOI: 10.1056/NEJM197709082971002  0.473
1977 Hirsch MJ, Growdon JH, Wurtman RJ. Increase in hippocampal acetylcholine after choline administration. Brain Research. 125: 383-5. PMID 851886 DOI: 10.1016/0006-8993(77)90634-5  0.431
1977 Growdon JH, Cohen EL, Wurtman RJ. Huntington's disease: clinical and chemical effects of choline administration. Annals of Neurology. 1: 418-22. PMID 152596 DOI: 10.1002/ana.410010503  0.453
1977 Growdon JH, Cohen EL, Wurtman RJ. Effects of oral choline administration on serum and CSF choline levels in patients with Huntington's disease. Journal of Neurochemistry. 28: 229-31. PMID 137960 DOI: 10.1111/j.1471-4159.1977.tb07732.x  0.489
1977 Wurtman RJ, Hirsch MJ, Growdon JH. Lecithin consumption raises serum-free-choline levels. Lancet (London, England). 2: 68-9. PMID 69151 DOI: 10.1016/S0140-6736(77)90067-8  0.371
1977 Growdon JH, Cohen EL, Wurtman RJ. Treatment of brain disease with dietary precursors of neurotransmitters. Annals of Internal Medicine. 86: 337-9. PMID 14577 DOI: 10.7326/0003-4819-86-3-337  0.488
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