Mark E. Burkard, Ph.D. - Publications

Affiliations: 
2000 University of Rochester, Rochester, NY 
Area:
Biochemistry

63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Denu RA, Burkard ME. Analysis of the "centrosome-ome" identifies MCPH1 deletion as a cause of centrosome amplification in human cancer. Scientific Reports. 10: 11921. PMID 32681070 DOI: 10.1038/S41598-020-68629-4  0.323
2020 Sharick JT, Walsh CM, Sprackling CM, Pasch CA, Pham DL, Esbona K, Choudhary A, Garcia-Valera R, Burkard ME, McGregor SM, Matkowskyj KA, Parikh AA, Meszoely IM, Kelley MC, Tsai S, et al. Metabolic Heterogeneity in Patient Tumor-Derived Organoids by Primary Site and Drug Treatment. Frontiers in Oncology. 10: 553. PMID 32500020 DOI: 10.3389/Fonc.2020.00553  0.356
2020 Singh A, Denu RA, Wolfe SK, Sperger JM, Schehr J, Witkowsky T, Esbona K, Chappell RJ, Weaver BA, Burkard ME, Lang JM. Centrosome amplification is a frequent event in circulating tumor cells from subjects with metastatic breast cancer. Molecular Oncology. PMID 32255253 DOI: 10.1002/1878-0261.12687  0.335
2020 Parsons BM, Meier DR, Richmond CS, Gurda GT, Lofgren KA, Burkard ME, Deming DA, Kenny PA. Acquisition of Cabozantinib-Sensitive MET D1228N Mutation During Progression on Crizotinib in MET-Amplified Triple-Negative Breast Cancer. Clinical Breast Cancer. PMID 32234363 DOI: 10.1016/J.Clbc.2020.02.003  0.365
2020 Emmerich P, Matkowskyj KA, McGregor S, Kraus S, Bischel K, Qyli T, Buehler D, Pasch C, Babiarz C, Depke M, Clipson L, Wisinski KB, Burkard ME, Baschnagel A, Uboha NV, et al. VCAN accumulation and proteolysis as predictors of T lymphocyte-excluded and permissive tumor microenvironments. Journal of Clinical Oncology. 38: 3127-3127. DOI: 10.1200/Jco.2020.38.15_Suppl.3127  0.344
2020 Rocque G, Gilbert A, Williams CP, Nakhmani A, Kandhare PG, Azuero A, Bhatia S, Kenzik KM, Burkard ME. Abstract P2-15-05: Visualization of the relationship between survival and sequential treatments in metastatic breast cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P2-15-05  0.341
2020 Wildiers H, Boni V, Saura C, Oliveira M, Jhaveri K, Won H, Bidard F, Brufsky AM, Burkard ME, Cervantes A, Fernández-Martos C, Haley B, Loi S, Spanggaard I, Panni S, et al. Abstract P1-19-08: Neratinib + trastuzumab + fulvestrant for HER2-mutant, hormone receptor-positive, metastatic breast cancer: Updated results from the phase 2 SUMMIT ‘basket’ trial Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P1-19-08  0.384
2020 Hu Y, Jin N, Manasrah BK, McGregor SM, Scribano C, Tucker JB, Yan R, Lera RF, Weaver BA, Burkard ME. Abstract 2248: Paclitaxel-induced micronucleation activates pro-inflammatory cGAS/STING signaling in triple negative breast cancer Immunology. DOI: 10.1158/1538-7445.Am2020-2248  0.332
2019 Pasch CA, Favreau PF, Yueh AE, Babiarz CP, Gillette A, Sharick JT, Karim MR, Nickel KP, DeZeeuw AK, Sprackling CM, Emmerich PB, DeStefanis RA, Pitera RT, Payne SN, Korkos DP, ... ... Burkard ME, et al. Patient-derived cancer organoid cultures to predict sensitivity to chemotherapy and radiation. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31175091 DOI: 10.1158/1078-0432.Ccr-18-3590  0.338
2019 Gilbert A, Kandhare P, Nakhmani A, Meersman SC, Garrett-Mayer E, Kaltenbaugh M, Burkard ME, Williams C, Azuero A, Bhatia S, Kenzik K, Rocque GB. Utilizing visualization to qualitatively evaluate electronic health record-derived database limitations. Journal of Clinical Oncology. 37: 317-317. DOI: 10.1200/Jco.2019.37.27_Suppl.317  0.343
2019 Gilbert A, Williams C, Kandhare P, Nakhmani A, Meersman SC, Garrett-Mayer E, Kaltenbaugh M, Azuero A, Ingram SA, Burkard ME, Bhatia S, Kenzik K, Rocque GB. Visualizing treatment patterns and survival in metastatic breast cancer. Journal of Clinical Oncology. 37: 316-316. DOI: 10.1200/Jco.2019.37.27_Suppl.316  0.321
2019 Matrana MR, Tomlins SA, Kwiatkowski K, Mitchell K, Suga JM, Dees EC, Burkard ME, Khatri J, Safa MM, Yang ES, Parsons B, Menter AR, Thompson MA, Gonzalez AO, Wassenaar TR, et al. No-cost next generation sequencing of advanced cancer patients within the Strata Precision Oncology Network supports clinical trial enrollment. Journal of Clinical Oncology. 37: 3073-3073. DOI: 10.1200/Jco.2019.37.15_Suppl.3073  0.311
2019 Yan R, Longhurst C, Lee K, Gilbert A, Alexandridis R, McGregor S, Laffin J, Rocque G, Burkard M. Abstract P3-06-14: Whole exome analysis of extreme long-term survivors with metastatic breast cancer Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-P3-06-14  0.341
2019 Burkard M, Lemmon K, Gilbert A, Zhang X, Trentham-Dietz A, Dahl E, Rocque G. Abstract P1-08-15: Characteristics of long-term survivors with metastatic breast cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-P1-08-15  0.365
2019 Sharifi M, Wisinski K, Burkard M, Tevaarwerk A, Tamkus D, Chan N, Truica C, Danciu O, Hoskins K, O'Regan R. Abstract OT1-02-01: Phase I trial of bicalutamide and ribociclib in androgen receptor-positive triple negative breast cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-Ot1-02-01  0.365
2019 Sprackling CM, Kratz JD, Favreau PF, Karim MR, Babiarz CP, Pasch CA, Gillette AA, Clipson L, Matkowskyj KA, Eichoff JC, Lemmon KK, Houtler HK, Burkard ME, Miller D, Skala MC, et al. Abstract 3143: Predicting treatment response using patient derived organotypic cancer spheroids Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-3143  0.331
2019 Kratz J, Uboha N, Lemmon K, Houtler H, Burkard M, Deming D. Abstract 1414: Durable response to first-line Trastuzumab in HER2 amplified colorectal cancer Cancer Research. 79: 1414-1414. DOI: 10.1158/1538-7445.Am2019-1414  0.367
2018 Fricke SL, Payne SN, Favreau PF, Kratz JD, Pasch CA, Foley TM, Yueh AE, Van De Hey DR, Depke MG, Korkos DP, Sha GC, DeStefanis RA, Clipson L, Burkard ME, Lemmon KK, et al. MTORC1/2 inhibition as a therapeutic strategy for PIK3CA mutant cancers. Molecular Cancer Therapeutics. PMID 30425131 DOI: 10.1158/1535-7163.Mct-18-0510  0.343
2018 Jin N, Burkard ME. MACROD2, an Original Cause of CIN? Cancer Discovery. 8: 921-923. PMID 30076143 DOI: 10.1158/2159-8290.Cd-18-0674  0.303
2018 Denu RA, Shabbir M, Nihal M, Singh CK, Longley BJ, Burkard ME, Ahmad N. Centriole Overduplication is the Predominant Mechanism Leading to Centrosome Amplification in Melanoma. Molecular Cancer Research : McR. PMID 29330283 DOI: 10.1158/1541-7786.Mcr-17-0197  0.308
2018 Sharick J, Walsh A, Sanders M, Kelley M, Meszoely I, Hooks M, Burkard M, Esbona K, Choudhary A, Skala M. Abstract P5-01-01: Personalized neoadjuvant treatment planning using optical metabolic imaging Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P5-01-01  0.373
2018 Esbona K, Jin N, Correia-Staudt K, Lager A, Heidke T, Laffin J, Weaver B, Burkard M. Abstract P4-03-09: Chromosomal instability predicts taxane sensitivity in breast cancer Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P4-03-09  0.395
2018 Ejebe I, Denu R, Longhurst C, Bauman J, MacGregor S, Lee K, Burkard M. Abstract P3-04-05: Outliers—extreme long-term survivors with metastatic breast cancer Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P3-04-05  0.386
2018 Jin N, Burkard M. Abstract 3797: Chromosome instability as a prognostic factor& an immunotherapeutic target in acute myeloid leukemia Cancer Research. 78: 3797-3797. DOI: 10.1158/1538-7445.Am2018-3797  0.321
2018 Singh A, Denu RA, Sperger JM, Weaver BA, Burkard ME, Lang JM. Abstract 3604: Centrosome amplification in epcam-captured circulating tumor cells from metastatic cancer patients Cancer Research. 78: 3604-3604. DOI: 10.1158/1538-7445.Am2018-3604  0.375
2017 Ma CX, Suman V, Goetz MP, Northfelt DW, Burkard ME, Ademuyiwa F, Naughton MJ, Margenthaler J, Aft R, Gray RJ, Tevaarwerk AJ, Wilke LG, Haddad TC, Moynihan T, Loprenzi C, et al. A Phase II trial of neoadjuvant MK2206, an AKT inhibitor, with anastrozole in clinical stage 2 or 3 PIK3CA mutant ER positive and HER2 negative breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28874413 DOI: 10.1158/1078-0432.Ccr-17-1260  0.355
2017 Denu RA, Burkard ME. Synchronous Bilateral Breast Cancer in a Patient With Nager Syndrome. Clinical Breast Cancer. PMID 28139434 DOI: 10.1016/J.Clbc.2016.12.009  0.347
2017 Denu RA, Burkard ME. Abstract A01: Centrosome amplification induces autophagy and sensitizes to chloroquine Clinical Cancer Research. 23. DOI: 10.1158/1557-3265.Pmccavuln16-A01  0.314
2017 Tevaarwerk A, Buhr K, Conkright W, Onitilo A, Robinson E, Hegeman R, Ahuja H, Kwong R, Nanad R, Dennee A, Koehn T, Burkard M, Wisinski K, Wiegmann D, Sesto M. Abstract P5-13-03: Prospective study of work limitations in breast cancer patients (pts) undergoing curative chemotherapy (CTx) Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P5-13-03  0.362
2017 Singh A, Sperger JM, Schehr J, Witkowski T, Weaver BA, Burkard ME, Lang JM. Abstract 3784: Expression of estrogen receptor specific signaling transcriptome in epithelial cell adhesion molecule (EpCAM) captured circulating tumor cells from patients with breast cancer Cancer Research. 77: 3784-3784. DOI: 10.1158/1538-7445.Am2017-3784  0.343
2016 Rampurwala M, Wisinski KB, Burkard ME, Ehsani S, O'Regan RM, Carmichael L, Kim K, Kolesar J, Tevaarwerk AJ. Phase 1b study of orteronel in postmenopausal women with hormone-receptor positive (HR+) metastatic breast cancer. Investigational New Drugs. PMID 27826831 DOI: 10.1007/S10637-016-0403-2  0.334
2016 Wisinski KB, Xu W, Tevaarwerk AJ, Saha S, Kim K, Traynor A, Dietrich L, Hegeman R, Patel D, Blank J, Harter J, Burkard ME. Targeting Estrogen Receptor Beta in a Phase 2 Study of High-Dose Estradiol in Metastatic Triple-Negative Breast Cancer: A Wisconsin Oncology Network Study. Clinical Breast Cancer. PMID 27133732 DOI: 10.1016/J.Clbc.2016.03.005  0.333
2016 Wisinski KB, Tevaarwerk AJ, Burkard ME, Rampurwalla M, Eickhoff J, Bell MC, Kolesar JM, Flynn C, Liu G. Phase 1 study of an AKT-inhibitor (MK-2206) combined with lapatinib in adult solid tumors followed by dose-expansion in advanced HER2+ breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27026198 DOI: 10.1158/1078-0432.Ccr-15-2365  0.34
2016 Denu RA, Zasadil LM, Kanugh C, Laffin J, Weaver BA, Burkard ME. Centrosome amplification induces high grade features and is prognostic of worse outcomes in breast cancer. Bmc Cancer. 16: 47. PMID 26832928 DOI: 10.1186/S12885-016-2083-X  0.353
2016 Rampurwala M, Choudhary A, Burkard M. Abstract P6-13-16: Ropidoxuridine (IPdR) potentiates alisertib (MLN8237) activity in triple-negative breast cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P6-13-16  0.412
2016 Ma C, Suman V, Goetz M, Northfelt D, Burkard M, Ademuyiwa F, Naughton M, Margenthaler J, Aft R, Gray R, Tavaarwerk A, Wilke L, Haddad T, Moynihan T, Loprinzi C, et al. Abstract P5-13-04: A phase II neoadjuvant trial of MK-2206, an AKT inhibitor, in combination with anastrozole for clinical stage 2 or 3 PIK3CA mutant estrogen receptor positive HER2 negative (ER+HER2-) breast cancer (BC) Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P5-13-04  0.338
2016 Cavalcante L, Denu R, Zasadil L, Weaver B, Burkard M. Abstract P3-07-53: Chromosomal instability as a predictor of sensitivity to paclitaxel Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P3-07-53  0.41
2015 Choudhary A, Zachek B, Lera RF, Zasadil LM, Lasek A, Denu RA, Kim H, Kanugh C, Laffin J, Harter JM, Wisinski KB, Saha S, Weaver BA, Burkard ME. Identification of selective lead compounds for treatment of high-ploidy breast cancer. Molecular Cancer Therapeutics. PMID 26586723 DOI: 10.1158/1535-7163.Mct-15-0527  0.398
2015 Denu RA, Burkard ME. Centrosome amplification and prognosis in breast cancer. Journal of Clinical Oncology. 33: 11036-11036. DOI: 10.1200/Jco.2015.33.15_Suppl.11036  0.34
2015 Nazeef M, Tevaarwerk AJ, Eickhoff J, Burkard ME, Heideman J, Liu G, Flynn C, Kolesar JM, Wisinski KB. Abstract P5-19-20: A phase I study of MK-2206 in combination with lapatinib in patients with advanced solid tumors followed by dose-expansion in advanced HER2+ breast cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P5-19-20  0.373
2015 Tevaarwerk AJ, Buhr KA, Wisinski KB, Burkard M, Gribble M, Hocking W, Sun W, Donohue S, Zeal J, Terhaar A, Wiegman DA, Sesto ME. Abstract P1-09-15: Randomized clinical trial assessing the impact of survivorship care plans on survivor knowledge Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P1-09-15  0.327
2014 Robins HI, Burkard ME, Halberg RB. "TRIMing" the patient population to increase the benefit of mTOR inhibition. Journal of the National Cancer Institute. 106. PMID 24777109 DOI: 10.1093/Jnci/Dju095  0.343
2014 Zasadil LM, Andersen KA, Yeum D, Rocque GB, Wilke LG, Tevaarwerk AJ, Raines RT, Burkard ME, Weaver BA. Cytotoxicity of paclitaxel in breast cancer is due to chromosome missegregation on multipolar spindles. Science Translational Medicine. 6: 229ra43. PMID 24670687 DOI: 10.1126/Scitranslmed.3007965  0.368
2014 Burkard ME, Wisinski KB, Njiaju UO, Donohue S, Hegeman R, Stella A, Mansky P, Shah V, Goggins T, Qamar R, Dietrich L, Kim K, Traynor AM, Tevaarwerk AJ. Feasibility of 4 cycles of docetaxel and cyclophosphamide every 14 days as an adjuvant regimen for breast cancer: a Wisconsin Oncology Network study. Clinical Breast Cancer. 14: 205-11. PMID 24342730 DOI: 10.1016/J.Clbc.2013.10.018  0.351
2014 Rampurwala MM, Burkard ME, Wisinski KB, Chimeh SE, Zeal J, Koehn T, Champeny TL, Rettig J, Kim K, Kolesar J, Tevaarwerk A. Phase 1b study of orteronel in postmenopausal women with hormone-receptor positive (HR+) metastatic breast cancer. Journal of Clinical Oncology. 32: 538-538. DOI: 10.1200/Jco.2014.32.15_Suppl.538  0.368
2014 Rampurwala MM, Choudhary A, Burkard ME. Abstract 2638: Novel synergy of radiosensitizer prodrug IPdR with Aurora kinase inhibitors in triple-negative breast cancer Cancer Research. 74: 2638-2638. DOI: 10.1158/1538-7445.Am2014-2638  0.416
2014 Burkard ME, Choudhary A, Lera RF, Fedenia R, Kanugh C, Laffin JJ, Zasadil LM, Weaver BA, Wisinski KB. Abstract 2526: Polyploidy: A new breast cancer subtype and a lead compound that targets it with high selectivity Cancer Research. 74: 2526-2526. DOI: 10.1158/1538-7445.Am2014-2526  0.389
2013 Wisinski KB, Tevaarwerk A, Bell M, Burkard ME, Eickhoff JC, Wilding G, LoConte NK, Traynor AM, Hoang T, Heideman J, Kolesar J, Liu G. A phase I study of MK-2206 in combination with lapatinib in patients (pts) with advanced solid tumors. Journal of Clinical Oncology. 31: 2607-2607. DOI: 10.1200/Jco.2013.31.15_Suppl.2607  0.301
2013 Fothergill A, Burkard M. Abstract 1927: Polyploidy across breast cancer subtypes. Cancer Research. 73: 1927-1927. DOI: 10.1158/1538-7445.Am2013-1927  0.355
2013 Zasadil LM, Burkard M, Weaver BA. Abstract 1750: Clinically relevant paclitaxel concentrations cause chromosome missegregation rather than mitotic arrest. Cancer Research. 73: 1750-1750. DOI: 10.1158/1538-7445.Am2013-1750  0.377
2013 Wisinski K, Burkard M, Njiaju U, Donohue S, Hegeman R, Stella A, Mansky P, Shah V, Goggins T, Qamar R, Dietrich L, Kim K, Traynor A, Tevaarwerk A. Abstract P3-12-10: Feasibility of four cycles of docetaxel and cyclophosphamide every 14 days as an adjuvant regimen for breast cancer: A Wisconsin oncology network study Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-P3-12-10  0.358
2013 Rocque G, Rampurwala M, Burkard M. PO84 VISUALIZING TREATMENT AND OUTCOMES IN METASTATIC BREAST CANCER The Breast. 22: S48. DOI: 10.1016/S0960-9776(13)70097-3  0.312
2012 Burkard ME, Santamaria A, Jallepalli PV. Enabling and disabling polo-like kinase 1 inhibition through chemical genetics. Acs Chemical Biology. 7: 978-81. PMID 22422077 DOI: 10.1021/Cb200551P  0.307
2012 Rocque G, Onitilo A, Engel J, Pettke E, Boshoven A, Kim K, Rishi S, Waack B, Wisinski KB, Tevaarwerk A, Burkard ME. Adjuvant therapy for HER2+ breast cancer: practice, perception, and toxicity. Breast Cancer Research and Treatment. 131: 713-21. PMID 22065290 DOI: 10.1007/S10549-011-1862-Y  0.362
2011 Lera RF, Burkard ME. Abstract 2986: Partial inhibition of Plk1 is cytotoxic despite normal spindle structure Cancer Research. 71: 2986-2986. DOI: 10.1158/1538-7445.Am2011-2986  0.372
2011 Rocque G, Onitilo A, Engel J, Pettke E, Boshoven A, Zhang S, Kim K, Rishi S, Waack B, Wisinski K, Tevaarwerk A, Burkard M. P5-18-12: Perception, Practice and Toxicity of Adjuvant Treatment of HER2+ Breast Cancer in Wisconsin. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P5-18-12  0.33
2011 Ehsani S, Tevaarwerk A, Wilke L, Neuman H, Beckman C, Becker J, Stettner A, Strigel R, Szalkucki L, Burkard M, Wisinski K. P4-11-21: A Retrospective Analysis of Women at Increased Lifetime Risk for Breast Cancer: Referral Patterns to Subspecialty Providers, Recommendations and Outcomes. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P4-11-21  0.31
2010 Burkard ME, Jallepalli PV. Validating cancer drug targets through chemical genetics. Biochimica Et Biophysica Acta. 1806: 251-7. PMID 20708654 DOI: 10.1016/J.Bbcan.2010.08.002  0.336
2001 Burkard ME, Xia T, Turner DH. Thermodynamics of RNA internal loops with a guanosine-guanosine pair adjacent to another noncanonical pair. Biochemistry. 40: 2478-83. PMID 11327869 DOI: 10.1021/Bi0012181  0.506
1999 Mathews DH, Burkard ME, Freier SM, Wyatt JR, Turner DH. Predicting oligonucleotide affinity to nucleic acid targets. Rna (New York, N.Y.). 5: 1458-69. PMID 10580474 DOI: 10.1017/S1355838299991148  0.505
1999 Burkard ME, Turner DH, Tinoco I. APPENDIX 2: Schematic Diagrams of Secondary and Tertiary Structure Elements Cold Spring Harbor Monograph Archive. 37: 681-685. DOI: 10.1101/087969589.37.681  0.443
1999 Burkard ME, Turner DH, Tinoco I. 10 The Interactions That Shape RNA Structure Cold Spring Harbor Monograph Archive. 37: 233-264. DOI: 10.1101/087969589.37.233  0.48
1998 Xia T, SantaLucia J, Burkard ME, Kierzek R, Schroeder SJ, Jiao X, Cox C, Turner DH. Thermodynamic parameters for an expanded nearest-neighbor model for formation of RNA duplexes with Watson-Crick base pairs. Biochemistry. 37: 14719-35. PMID 9778347 DOI: 10.1021/Bi9809425  0.509
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