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Seppo Kaakkola - Publications

Affiliations: 
University of Helsinki, Helsingfors, Finland 
Area:
neurology
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21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2005 Janhunen S, Mielikäinen P, Paldánius P, Tuominen RK, Ahtee L, Kaakkola S. The effect of nicotine in combination with various dopaminergic drugs on nigrostriatal dopamine in rats. Naunyn-Schmiedeberg's Archives of Pharmacology. 371: 480-91. PMID 16012872 DOI: 10.1007/s00210-005-1066-2  0.418
2002 Heikkinen H, Varhe A, Laine T, Puttonen J, Kela M, Kaakkola S, Reinikainen K. Entacapone improves the availability of L-dopa in plasma by decreasing its peripheral metabolism independent of L-dopa/carbidopa dose. British Journal of Clinical Pharmacology. 54: 363-71. PMID 12392583 DOI: 10.1046/j.1365-2125.2002.01654.x  0.339
1997 Lyytinen J, Kaakkola S, Ahtila S, Tuomainen P, Teräväinen H. Simultaneous MAO-B and COMT inhibition in L-Dopa-treated patients with Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 12: 497-505. PMID 9251066 DOI: 10.1002/mds.870120404  0.303
1995 Ahtila S, Kaakkola S, Gordin A, Korpela K, Heinävaara S, Karlsson M, Wikberg T, Tuomainen P, Männistö PT. Effect of entacapone, a COMT inhibitor, on the pharmacokinetics and metabolism of levodopa after administration of controlled-release levodopa-carbidopa in volunteers. Clinical Neuropharmacology. 18: 46-57. PMID 8665534  0.346
1994 Kaakkola S, Teräväinen H, Ahtila S, Rita H, Gordin A. Effect of entacapone, a COMT inhibitor, on clinical disability and levodopa metabolism in parkinsonian patients. Neurology. 44: 77-80. PMID 8290096  0.33
1994 Törnwall M, Kaakkola S, Tuomainen P, Kask A, Männistö PT. Comparison of two new inhibitors of catechol O-methylation on striatal dopamine metabolism: a microdialysis study in rats. British Journal of Pharmacology. 112: 13-8. PMID 7518301  0.387
1993 Kaakkola S, Wurtman RJ. Effects of catechol-O-methyltransferase inhibitors and L-3,4-dihydroxyphenylalanine with or without carbidopa on extracellular dopamine in rat striatum. Journal of Neurochemistry. 60: 137-44. PMID 8417137 DOI: 10.1111/j.1471-4159.1993.tb05831.x  0.507
1993 Kaakkola S, Wurtman RJ. Effects of two diketopiperazines, cyclo (His-Pro) and cyclo (Asp-Phe), on striatal dopamine: a microdialysis study. Brain Research Bulletin. 32: 667-72. PMID 7693310 DOI: 10.1016/0361-9230(93)90171-7  0.547
1992 Kaakkola S, Tuomainen P, Wurtman RJ, Männistö PT. Effects of systemic carbidopa on dopamine synthesis in rat hypothalamus and striatum. Journal of Neural Transmission. Parkinson's Disease and Dementia Section. 4: 143-54. PMID 1571078 DOI: 10.1007/BF02251477  0.384
1992 Gardier AM, Kaakkola S, Erfurth A, Wurtman RJ. Effects of methiothepin on changes in brain serotonin release induced by repeated administration of high doses of anorectic serotoninergic drugs. Brain Research. 588: 67-74. PMID 1382807 DOI: 10.1016/0006-8993(92)91345-F  0.43
1992 Kaakkola S, Wurtman RJ. Effects of COMT inhibitors on striatal dopamine metabolism: a microdialysis study. Brain Research. 587: 241-9. PMID 1381981 DOI: 10.1016/0006-8993(92)91003-W  0.564
1990 Kaakkola S, Gordin A, Järvinen M, Wikberg T, Schultz E, Nissinen E, Pentikäinen PJ, Rita H. Effect of a novel catechol-O-methyltransferase inhibitor, nitecapone, on the metabolism of L-dopa in healthy volunteers. Clinical Neuropharmacology. 13: 436-47. PMID 2272023  0.357
1990 Männistö PT, Tuomainen P, Toivonen M, Törnwall M, Kaakkola S. Effect of acute levodopa on brain catecholamines after selective MAO and COMT inhibition in male rats. Journal of Neural Transmission. Parkinson's Disease and Dementia Section. 2: 31-43. PMID 2113389 DOI: 10.1007/BF02251244  0.441
1988 Lindén IB, Nissinen E, Etemadzadeh E, Kaakkola S, Männistö P, Pohto P. Favorable effect of catechol-O-methyltransferase inhibition by OR-462 in experimental models of Parkinson's disease. The Journal of Pharmacology and Experimental Therapeutics. 247: 289-93. PMID 3171977  0.401
1985 Kaakkola S, Männistö PT, Nissinen E, Vuorela A, Mäntylä R. The effect of an increased ratio of carbidopa to levodopa on the pharmacokinetics of levodopa. Acta Neurologica Scandinavica. 72: 385-91. PMID 4082903  0.352
1982 Kaakkola S, Lehtosalo J, Laitinen LA. Changes in blood-brain barrier permeability to drugs in decompressed rats. Undersea Biomedical Research. 9: 233-40. PMID 6890252  0.304
1981 Kaakkola S. Effect of nicotinic and muscarinic drugs on amphetamine- and apomorphine-induced circling behaviour in rats. Acta Pharmacologica Et Toxicologica. 48: 162-7. PMID 7257827  0.389
1981 Männistö P, Mattila J, Kaakkola S. Possible involvement of nigrostriatal dopamine system in the inhibition of thyrotropin secretion in the rat. European Journal of Pharmacology. 76: 403-9. PMID 6799305 DOI: 10.1016/0014-2999(81)90111-4  0.455
1980 Kaakkola S, Kääriäinen I. Contralateral circling behaviour induced by intranigral injection of taurine in rats. Acta Pharmacologica Et Toxicologica. 46: 293-8. PMID 7368948  0.386
1980 Kaakkola S. Circling behaviour induced by intranigral injection of baclofen in rats. Archives Internationales De Pharmacodynamie Et De Thã©Rapie. 244: 113-22. PMID 7191245  0.37
1978 Ahtee L, Kaakkola S. Effect of mecamylamine on the fate of dopamine in striatal and mesolimbic areas of rat brain; interaction with morphine and haloperidol. British Journal of Pharmacology. 62: 213-8. PMID 564219  0.395
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