Steve Zeisel - Publications

Affiliations: 
University of North Carolina, Chapel Hill, Chapel Hill, NC 

235 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Wallace TC, Blusztajn JK, Caudill MA, Klatt KC, Zeisel SH. Choline: The Neurocognitive Essential Nutrient of Interest to Obstetricians and Gynecologists. Journal of Dietary Supplements. 1-20. PMID 31385730 DOI: 10.1080/19390211.2019.1639875  0.72
2019 Trujillo-Gonzalez I, Friday WB, Munson CA, Bachleda A, Weiss ER, Alam NM, Sha W, Zeisel SH, Surzenko N. Low availability of choline disrupts development and function of the retina. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201900444R. PMID 31091977 DOI: 10.1096/Fj.201900444R  0.48
2018 Trujillo-Gonzalez I, Wang Y, Friday WB, Vickers KC, Toth CL, Molina-Torres L, Surzenko N, Zeisel SH. microRNA-129-5p is regulated by choline availability and controls EGF receptor synthesis and neurogenesis in the cerebral cortex. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201801094RR. PMID 30521373 DOI: 10.1096/Fj.201801094Rr  0.48
2017 Lupu DS, Orozco LD, Wang Y, Cullen JM, Pellegrini M, Zeisel SH. Altered methylation of specific DNA loci in the liver of Bhmt-null mice results in repression of Iqgap2 and F2rl2 and is associated with development of preneoplastic foci. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28179424 DOI: 10.1096/Fj.201601169R  0.48
2016 Qian L, Zhao A, Zhang Y, Chen T, Zeisel SH, Jia W, Cai W. Metabolomic Approaches to Explore Chemical Diversity of Human Breast-Milk, Formula Milk and Bovine Milk. International Journal of Molecular Sciences. 17. PMID 27999311 DOI: 10.3390/ijms17122128  0.4
2016 Nilsson TK, Hurtig-Wennlöf A, Sjöström M, Herrmann W, Obeid R, Owen JR, Zeisel S. Plasma 1-carbon metabolites and academic achievement in 15-yr-old adolescents. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26728177 DOI: 10.1096/fj.15-281097  0.8
2015 Wang Y, Surzenko N, Friday WB, Zeisel SH. Maternal dietary intake of choline in mice regulates development of the cerebral cortex in the offspring. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26700730 DOI: 10.1096/Fj.15-282426  0.8
2015 Wozniak JR, Fuglestad AJ, Eckerle JK, Fink BA, Hoecker HL, Boys CJ, Radke JP, Kroupina MG, Miller NC, Brearley AM, Zeisel SH, Georgieff MK. Choline supplementation in children with fetal alcohol spectrum disorders: a randomized, double-blind, placebo-controlled trial. The American Journal of Clinical Nutrition. PMID 26447156 DOI: 10.3945/Ajcn.114.099168  0.8
2015 Strauss KA, Ferreira C, Bottiglieri T, Zhao X, Arning E, Zhang S, Zeisel SH, Escolar ML, Presnick N, Puffenberger EG, Vugrek O, Kovacevic L, Wagner C, Mazariegos GV, Mudd SH, et al. Liver transplantation for treatment of severe S-adenosylhomocysteine hydrolase deficiency. Molecular Genetics and Metabolism. PMID 26095522 DOI: 10.1016/J.Ymgme.2015.06.005  0.8
2015 Zhao X, Zeisel S, Zhang S. A rapid LC-MRM/MS assay for simultaneous quantification of choline, betaine, trimethylamine, trimethylamine N-oxide and creatinine in human plasma and urine. Electrophoresis. PMID 26081221 DOI: 10.1002/elps.201500055  0.8
2015 Silver MJ, Corbin KD, Hellenthal G, da Costa KA, Dominguez-Salas P, Moore SE, Owen J, Prentice AM, Hennig BJ, Zeisel SH. Evidence for negative selection of gene variants that increase dependence on dietary choline in a Gambian cohort. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 25921832 DOI: 10.1096/Fj.15-271056  0.8
2015 Tsuchiya H, da Costa KA, Lee S, Renga B, Jaeschke H, Yang Z, Orena SJ, Goedken MJ, Zhang Y, Kong B, Lebofsky M, Rudraiah S, Smalling R, Guo G, Fiorucci S, ... Zeisel SH, et al. Interactions Between Nuclear Receptor SHP and FOXA1 Maintain Oscillatory Homocysteine Homeostasis in Mice. Gastroenterology. 148: 1012-1023.e14. PMID 25701738 DOI: 10.1053/j.gastro.2015.01.045  0.8
2015 Schenkel LC, Singh RK, Michel V, Zeisel SH, da Costa KA, Johnson AR, Mudd HS, Bakovic M. Mechanism of choline deficiency and membrane alteration in postural orthostatic tachycardia syndrome primary skin fibroblasts. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 1663-75. PMID 25466896 DOI: 10.1096/fj.14-258566  0.8
2015 Martínez-Vega R, Garrido F, Partearroyo T, Cediel R, Zeisel SH, Martínez-Álvarez C, Varela-Moreiras G, Varela-Nieto I, Pajares MA. Folic acid deficiency induces premature hearing loss through mechanisms involving cochlear oxidative stress and impairment of homocysteine metabolism. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 418-32. PMID 25384423 DOI: 10.1096/fj.14-259283  0.8
2015 Orena S, Owen J, Jin F, Fabian M, Gillitt ND, Zeisel SH. Extracts of fruits and vegetables activate the antioxidant response element in IMR-32 cells Journal of Nutrition. 145: 2006-2011. DOI: 10.3945/jn.115.216705  0.8
2014 Miller CA, Corbin KD, da Costa KA, Zhang S, Zhao X, Galanko JA, Blevins T, Bennett BJ, O'Connor A, Zeisel SH. Effect of egg ingestion on trimethylamine-N-oxide production in humans: a randomized, controlled, dose-response study. The American Journal of Clinical Nutrition. 100: 778-86. PMID 24944063 DOI: 10.3945/Ajcn.114.087692  0.8
2014 Dominguez-Salas P, Moore SE, Baker MS, Bergen AW, Cox SE, Dyer RA, Fulford AJ, Guan Y, Laritsky E, Silver MJ, Swan GE, Zeisel SH, Innis SM, Waterland RA, Prentice AM, et al. Maternal nutrition at conception modulates DNA methylation of human metastable epialleles. Nature Communications. 5: 3746. PMID 24781383 DOI: 10.1038/Ncomms4746  0.8
2014 da Costa KA, Corbin KD, Niculescu MD, Galanko JA, Zeisel SH. Identification of new genetic polymorphisms that alter the dietary requirement for choline and vary in their distribution across ethnic and racial groups. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 2970-8. PMID 24671709 DOI: 10.1096/Fj.14-249557  0.8
2013 Du X, Zeisel SH. Spectral deconvolution for gas chromatography mass spectrometry-based metabolomics: current status and future perspectives. Computational and Structural Biotechnology Journal. 4: e201301013. PMID 24688694 DOI: 10.5936/Csbj.201301013  0.8
2013 Wozniak JR, Fuglestad AJ, Eckerle JK, Kroupina MG, Miller NC, Boys CJ, Brearley AM, Fink BA, Hoecker HL, Zeisel SH, Georgieff MK. Choline supplementation in children with fetal alcohol spectrum disorders has high feasibility and tolerability. Nutrition Research (New York, N.Y.). 33: 897-904. PMID 24176229 DOI: 10.1016/J.Nutres.2013.08.005  0.8
2013 Zheng X, Qiu Y, Zhong W, Baxter S, Su M, Li Q, Xie G, Ore BM, Qiao S, Spencer MD, Zeisel SH, Zhou Z, Zhao A, Jia W. A targeted metabolomic protocol for short-chain fatty acids and branched-chain amino acids. Metabolomics : Official Journal of the Metabolomic Society. 9: 818-827. PMID 23997757 DOI: 10.1007/s11306-013-0500-6  0.8
2013 Fuglestad AJ, Fink BA, Eckerle JK, Boys CJ, Hoecker HL, Kroupina MG, Zeisel SH, Georgieff MK, Wozniak JR. Inadequate intake of nutrients essential for neurodevelopment in children with fetal alcohol spectrum disorders (FASD). Neurotoxicology and Teratology. 39: 128-32. PMID 23871794 DOI: 10.1016/J.Ntt.2013.06.005  0.8
2013 Xie G, Zhong W, Li H, Li Q, Qiu Y, Zheng X, Chen H, Zhao X, Zhang S, Zhou Z, Zeisel SH, Jia W. Alteration of bile acid metabolism in the rat induced by chronic ethanol consumption. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 3583-93. PMID 23709616 DOI: 10.1096/fj.13-231860  0.8
2013 Zeisel SH. Nutrition in pregnancy: the argument for including a source of choline. International Journal of Women's Health. 5: 193-9. PMID 23637565 DOI: 10.2147/IJWH.S36610  0.8
2013 Dominguez-Salas P, Moore SE, Cole D, da Costa KA, Cox SE, Dyer RA, Fulford AJ, Innis SM, Waterland RA, Zeisel SH, Prentice AM, Hennig BJ. DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women. The American Journal of Clinical Nutrition. 97: 1217-27. PMID 23576045 DOI: 10.3945/Ajcn.112.048462  0.8
2013 Mehedint MG, Zeisel SH. Choline's role in maintaining liver function: new evidence for epigenetic mechanisms. Current Opinion in Clinical Nutrition and Metabolic Care. 16: 339-45. PMID 23493015 DOI: 10.1097/MCO.0b013e3283600d46  0.8
2013 Corbin KD, Abdelmalek MF, Spencer MD, da Costa KA, Galanko JA, Sha W, Suzuki A, Guy CD, Cardona DM, Torquati A, Diehl AM, Zeisel SH. Genetic signatures in choline and 1-carbon metabolism are associated with the severity of hepatic steatosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 1674-89. PMID 23292069 DOI: 10.1096/Fj.12-219097  0.8
2013 Zeisel SH. Metabolic crosstalk between choline/1-carbon metabolism and energy homeostasis. Clinical Chemistry and Laboratory Medicine : Cclm / Fescc. 51: 467-75. PMID 23072856 DOI: 10.1515/cclm-2012-0518  0.8
2013 Zeisel SH, Waterland RA, Ordovás JM, Muoio DM, Jia W, Fodor A. Highlights of the 2012 Research Workshop: Using nutrigenomics and metabolomics in clinical nutrition research. Jpen. Journal of Parenteral and Enteral Nutrition. 37: 190-200. PMID 23042849 DOI: 10.1177/0148607112462401  0.8
2012 Zeisel SH. A brief history of choline. Annals of Nutrition & Metabolism. 61: 254-8. PMID 23183298 DOI: 10.1159/000343120  0.8
2012 Cheatham CL, Goldman BD, Fischer LM, da Costa KA, Reznick JS, Zeisel SH. Phosphatidylcholine supplementation in pregnant women consuming moderate-choline diets does not enhance infant cognitive function: a randomized, double-blind, placebo-controlled trial. The American Journal of Clinical Nutrition. 96: 1465-72. PMID 23134891 DOI: 10.3945/Ajcn.112.037184  0.8
2012 Teng YW, Cerdena I, Zeisel SH. Homocysteinemia in mice with genetic betaine homocysteine S-methyltransferase deficiency is independent of dietary folate intake. The Journal of Nutrition. 142: 1964-7. PMID 23014492 DOI: 10.3945/jn.112.166835  0.8
2012 Tsang V, Fry RC, Niculescu MD, Rager JE, Saunders J, Paul DS, Zeisel SH, Waalkes MP, Stýblo M, Drobná Z. The epigenetic effects of a high prenatal folate intake in male mouse fetuses exposed in utero to arsenic. Toxicology and Applied Pharmacology. 264: 439-50. PMID 22959928 DOI: 10.1016/J.Taap.2012.08.022  0.8
2012 Richman EL, Kenfield SA, Stampfer MJ, Giovannucci EL, Zeisel SH, Willett WC, Chan JM. Choline intake and risk of lethal prostate cancer: incidence and survival. The American Journal of Clinical Nutrition. 96: 855-63. PMID 22952174 DOI: 10.3945/Ajcn.112.039784  0.8
2012 Corbin KD, Zeisel SH. The nutrigenetics and nutrigenomics of the dietary requirement for choline. Progress in Molecular Biology and Translational Science. 108: 159-77. PMID 22656377 DOI: 10.1016/B978-0-12-398397-8.00007-1  0.8
2012 Zeisel SH. Diet-gene interactions underlie metabolic individuality and influence brain development: implications for clinical practice derived from studies on choline metabolism. Annals of Nutrition & Metabolism. 60: 19-25. PMID 22614815 DOI: 10.1159/000337310  0.8
2012 Johnson AR, Lao S, Wang T, Galanko JA, Zeisel SH. Choline dehydrogenase polymorphism rs12676 is a functional variation and is associated with changes in human sperm cell function. Plos One. 7: e36047. PMID 22558321 DOI: 10.1371/Journal.Pone.0036047  0.8
2012 Teng YW, Ellis JM, Coleman RA, Zeisel SH. Mouse betaine-homocysteine S-methyltransferase deficiency reduces body fat via increasing energy expenditure and impairing lipid synthesis and enhancing glucose oxidation in white adipose tissue. The Journal of Biological Chemistry. 287: 16187-98. PMID 22362777 DOI: 10.1074/Jbc.M111.303255  0.8
2012 Corbin KD, Zeisel SH. Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression. Current Opinion in Gastroenterology. 28: 159-65. PMID 22134222 DOI: 10.1097/Mog.0B013E32834E7B4B  0.8
2012 Zeisel SH. Dietary choline deficiency causes DNA strand breaks and alters epigenetic marks on DNA and histones. Mutation Research. 733: 34-8. PMID 22041500 DOI: 10.1016/j.mrfmmm.2011.10.008  0.8
2012 Su M, Zheng XY, Zhang T, Pei L, Wang F, Zheng X, Gu X, Song X, Lu X, Chen G, Bao Y, Chen T, Zhao A, Jia WP, Zeisel SH, et al. Integrated profiling of metabolites and trace elements reveals a multifaceted malnutrition in pregnant women from a region with a high prevalence of congenital malformations Metabolomics. 8: 831-844. DOI: 10.1007/s11306-011-0378-0  0.8
2012 Erdman JW, MacDonald IA, Zeisel SH. Present Knowledge in Nutrition: Tenth Edition Present Knowledge in Nutrition: Tenth Edition. DOI: 10.1002/9781119946045  0.8
2011 Teng YW, Mehedint MG, Garrow TA, Zeisel SH. Deletion of betaine-homocysteine S-methyltransferase in mice perturbs choline and 1-carbon metabolism, resulting in fatty liver and hepatocellular carcinomas. The Journal of Biological Chemistry. 286: 36258-67. PMID 21878621 DOI: 10.1074/Jbc.M111.265348  0.8
2011 Zeisel SH. The supply of choline is important for fetal progenitor cells. Seminars in Cell & Developmental Biology. 22: 624-8. PMID 21693194 DOI: 10.1016/j.semcdb.2011.06.002  0.8
2011 da Costa KA, Sanders LM, Fischer LM, Zeisel SH. Docosahexaenoic acid in plasma phosphatidylcholine may be a potential marker for in vivo phosphatidylethanolamine N-methyltransferase activity in humans. The American Journal of Clinical Nutrition. 93: 968-74. PMID 21411618 DOI: 10.3945/ajcn.110.011064  0.8
2011 Zeisel SH. Nutritional genomics: defining the dietary requirement and effects of choline. The Journal of Nutrition. 141: 531-4. PMID 21270363 DOI: 10.3945/jn.110.130369  0.8
2011 Zeisel SH. What choline metabolism can tell us about the underlying mechanisms of fetal alcohol spectrum disorders. Molecular Neurobiology. 44: 185-91. PMID 21259123 DOI: 10.1007/s12035-011-8165-5  0.8
2011 Spencer MD, Hamp TJ, Reid RW, Fischer LM, Zeisel SH, Fodor AA. Association between composition of the human gastrointestinal microbiome and development of fatty liver with choline deficiency. Gastroenterology. 140: 976-86. PMID 21129376 DOI: 10.1053/j.gastro.2010.11.049  0.8
2011 Resseguie ME, da Costa KA, Galanko JA, Patel M, Davis IJ, Zeisel SH. Aberrant estrogen regulation of PEMT results in choline deficiency-associated liver dysfunction. The Journal of Biological Chemistry. 286: 1649-58. PMID 21059658 DOI: 10.1074/Jbc.M110.106922  0.8
2011 Caudill M, Da Costa KA, Zeisel S, Hornick B. Elevating awareness and intake of choline: An essential nutrient for public health Nutrition Today. 46: 235-241. DOI: 10.1097/NT.0b013e31822dff64  0.8
2011 Zeisel SH. Dietary Choline, Betaine, Methionine, and Epigenetic Mechanisms Influencing Brain Development Nutrition in Epigenetics. 225-240. DOI: 10.1002/9780470959824.ch13  0.8
2010 Zeisel SH. A grand challenge for nutrigenomics. Frontiers in Genetics. 1: 2. PMID 22303299 DOI: 10.3389/fgene.2010.00002  0.8
2010 Zeisel SH. Choline: clinical nutrigenetic/nutrigenomic approaches for identification of functions and dietary requirements. Journal of Nutrigenetics and Nutrigenomics. 3: 209-19. PMID 21474952 DOI: 10.1159/000324357  0.8
2010 Adams KM, Kohlmeier M, Powell M, Zeisel SH. Nutrition in medicine: nutrition education for medical students and residents. Nutrition in Clinical Practice : Official Publication of the American Society For Parenteral and Enteral Nutrition. 25: 471-80. PMID 20962306 DOI: 10.1177/0884533610379606  0.8
2010 Fischer LM, da Costa KA, Kwock L, Galanko J, Zeisel SH. Dietary choline requirements of women: effects of estrogen and genetic variation. The American Journal of Clinical Nutrition. 92: 1113-9. PMID 20861172 DOI: 10.3945/Ajcn.2010.30064  0.8
2010 Cowherd RB, Cowerd RB, Asmar MM, Alderman JM, Alderman EA, Garland AL, Busby WH, Bodnar WM, Rusyn I, Medoff BD, Tisch R, Mayer-Davis E, Swenberg JA, Zeisel SH, Combs TP. Adiponectin lowers glucose production by increasing SOGA. The American Journal of Pathology. 177: 1936-45. PMID 20813965 DOI: 10.2353/Ajpath.2010.100363  0.8
2010 Adams KM, Kohlmeier M, Zeisel SH. Nutrition education in U.S. medical schools: latest update of a national survey. Academic Medicine : Journal of the Association of American Medical Colleges. 85: 1537-42. PMID 20736683 DOI: 10.1097/ACM.0b013e3181eab71b  0.8
2010 Blumberg J, Heaney RP, Huncharek M, Scholl T, Stampfer M, Vieth R, Weaver CM, Zeisel SH. Evidence-based criteria in the nutritional context. Nutrition Reviews. 68: 478-84. PMID 20646225 DOI: 10.1111/J.1753-4887.2010.00307.X  0.8
2010 Mehedint MG, Craciunescu CN, Zeisel SH. Maternal dietary choline deficiency alters angiogenesis in fetal mouse hippocampus. Proceedings of the National Academy of Sciences of the United States of America. 107: 12834-9. PMID 20624989 DOI: 10.1073/pnas.0914328107  0.8
2010 Fischer LM, da Costa KA, Galanko J, Sha W, Stephenson B, Vick J, Zeisel SH. Choline intake and genetic polymorphisms influence choline metabolite concentrations in human breast milk and plasma. The American Journal of Clinical Nutrition. 92: 336-46. PMID 20534746 DOI: 10.3945/Ajcn.2010.29459  0.8
2010 Zeisel SH. Choline: clinical nutrigenetic/nutrigenomic approaches for identification of functions and dietary requirements. World Review of Nutrition and Dietetics. 101: 73-83. PMID 20436254 DOI: 10.1159/000314512  0.8
2010 Craciunescu CN, Johnson AR, Zeisel SH. Dietary choline reverses some, but not all, effects of folate deficiency on neurogenesis and apoptosis in fetal mouse brain. The Journal of Nutrition. 140: 1162-6. PMID 20392884 DOI: 10.3945/jn.110.122044  0.8
2010 Sha W, da Costa KA, Fischer LM, Milburn MV, Lawton KA, Berger A, Jia W, Zeisel SH. Metabolomic profiling can predict which humans will develop liver dysfunction when deprived of dietary choline. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 2962-75. PMID 20371621 DOI: 10.1096/fj.09-154054  0.8
2010 Johnson AR, Craciunescu CN, Guo Z, Teng YW, Thresher RJ, Blusztajn JK, Zeisel SH. Deletion of murine choline dehydrogenase results in diminished sperm motility. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 2752-61. PMID 20371614 DOI: 10.1096/fj.09-153718  0.8
2010 Lee JE, Jacques PF, Dougherty L, Selhub J, Giovannucci E, Zeisel SH, Cho E. Are dietary choline and betaine intakes determinants of total homocysteine concentration? The American Journal of Clinical Nutrition. 91: 1303-10. PMID 20219967 DOI: 10.3945/Ajcn.2009.28456  0.8
2010 Craig SS, Craig SA, Ganio MS, Maresh CM, Horrace G, da Costa KA, Zeisel SH. The betaine content of sweat from adolescent females. Journal of the International Society of Sports Nutrition. 7: 3. PMID 20205750 DOI: 10.1186/1550-2783-7-3  0.8
2010 Lee JE, Giovannucci E, Fuchs CS, Willett WC, Zeisel SH, Cho E. Choline and betaine intake and the risk of colorectal cancer in men. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 19: 884-7. PMID 20160273 DOI: 10.1158/1055-9965.Epi-09-1295  0.8
2010 da Costa KA, Rai KS, Craciunescu CN, Parikh K, Mehedint MG, Sanders LM, McLean-Pottinger A, Zeisel SH. Dietary docosahexaenoic acid supplementation modulates hippocampal development in the Pemt-/- mouse. The Journal of Biological Chemistry. 285: 1008-15. PMID 19889625 DOI: 10.1074/jbc.M109.017137  0.8
2010 Mehedint MG, Niculescu MD, Craciunescu CN, Zeisel SH. Choline deficiency alters global histone methylation and epigenetic marking at the Re1 site of the calbindin 1 gene. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 184-95. PMID 19752176 DOI: 10.1096/Fj.09-140145  0.8
2010 Zhu X, Zeisel SH. Choline and phosphatidylcholine Encyclopedia of Human Nutrition. 392-396. DOI: 10.1016/B0-12-226694-3/00400-2  0.8
2009 Zeisel SH, da Costa KA. Choline: an essential nutrient for public health. Nutrition Reviews. 67: 615-23. PMID 19906248 DOI: 10.1111/j.1753-4887.2009.00246.x  0.8
2009 Rosales FJ, Reznick JS, Zeisel SH. Understanding the role of nutrition in the brain and behavioral development of toddlers and preschool children: identifying and addressing methodological barriers. Nutritional Neuroscience. 12: 190-202. PMID 19761650 DOI: 10.1179/147683009X423454  0.8
2009 Xu X, Gammon MD, Zeisel SH, Bradshaw PT, Wetmur JG, Teitelbaum SL, Neugut AI, Santella RM, Chen J. High intakes of choline and betaine reduce breast cancer mortality in a population-based study. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 4022-8. PMID 19635752 DOI: 10.1096/Fj.09-136507  0.8
2009 Zeisel SH. Epigenetic mechanisms for nutrition determinants of later health outcomes. The American Journal of Clinical Nutrition. 89: 1488S-1493S. PMID 19261726 DOI: 10.3945/ajcn.2009.27113B  0.8
2009 Bidulescu A, Chambless LE, Siega-Riz AM, Zeisel SH, Heiss G. Repeatability and measurement error in the assessment of choline and betaine dietary intake: the Atherosclerosis Risk in Communities (ARIC) study. Nutrition Journal. 8: 14. PMID 19232103 DOI: 10.1186/1475-2891-8-14  0.8
2009 Zeisel SH. Importance of methyl donors during reproduction. The American Journal of Clinical Nutrition. 89: 673S-7S. PMID 19116320 DOI: 10.3945/ajcn.2008.26811D  0.8
2009 Zeisel SH. Is maternal diet supplementation beneficial? Optimal development of infant depends on mother's diet. The American Journal of Clinical Nutrition. 89: 685S-7S. PMID 19116319 DOI: 10.3945/ajcn.2008.26811F  0.8
2009 Craciunescu CN, Niculescu MD, Guo Z, Johnson AR, Fischer L, Zeisel SH. Dose response effects of dermally applied diethanolamine on neurogenesis in fetal mouse hippocampus and potential exposure of humans. Toxicological Sciences : An Official Journal of the Society of Toxicology. 107: 220-6. PMID 18948303 DOI: 10.1093/Toxsci/Kfn227  0.8
2009 Xu X, Gammon MD, Zhang Y, Bestor TH, Zeisel SH, Wetmur JG, Wallenstein S, Bradshaw PT, Garbowski G, Teitelbaum SL, Neugut AI, Santella RM, Chen J. BRCA1 promoter methylation is associated with increased mortality among women with breast cancer. Breast Cancer Research and Treatment. 115: 397-404. PMID 18521744 DOI: 10.1007/S10549-008-0075-5  0.8
2008 Han J, Danell RM, Patel JR, Gumerov DR, Scarlett CO, Speir JP, Parker CE, Rusyn I, Zeisel S, Borchers CH. Towards high-throughput metabolomics using ultrahigh-field Fourier transform ion cyclotron resonance mass spectrometry. Metabolomics : Official Journal of the Metabolomic Society. 4: 128-140. PMID 19081807 DOI: 10.1007/S11306-008-0104-8  0.8
2008 Zeisel SH. Genetic polymorphisms in methyl-group metabolism and epigenetics: lessons from humans and mouse models. Brain Research. 1237: 5-11. PMID 18789905 DOI: 10.1016/j.brainres.2008.08.059  0.8
2008 Rosales FJ, Zeisel SH. Perspectives from the symposium: The role of nutrition in infant and toddler brain and behavioral development. Nutritional Neuroscience. 11: 135-43. PMID 18616870 DOI: 10.1179/147683008X301522  0.8
2008 Pop EA, Fischer LM, Coan AD, Gitzinger M, Nakamura J, Zeisel SH. Effects of a high daily dose of soy isoflavones on DNA damage, apoptosis, and estrogenic outcomes in healthy postmenopausal women: a phase I clinical trial. Menopause (New York, N.Y.). 15: 684-92. PMID 18446090 DOI: 10.1097/gme.0b013e318167b8f2  0.8
2008 Gossell-Williams M, Fletcher H, Zeisel SH. Unexpected depletion in plasma choline and phosphatidylcholine concentrations in a pregnant woman with bipolar affective disorder being treated with lithuim, haloperidol and benztropine: a case report. Journal of Medical Case Reports. 2: 55. PMID 18289387 DOI: 10.1186/1752-1947-2-55  0.8
2008 Zeisel SH. Is there a new component of the Mediterranean diet that reduces inflammation? The American Journal of Clinical Nutrition. 87: 277-8. PMID 18258614  0.8
2008 Xu X, Gammon MD, Zeisel SH, Lee YL, Wetmur JG, Teitelbaum SL, Bradshaw PT, Neugut AI, Santella RM, Chen J. Choline metabolism and risk of breast cancer in a population-based study. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 2045-52. PMID 18230680 DOI: 10.1096/Fj.07-101279  0.8
2007 Likes R, Madl RL, Zeisel SH, Craig SA. The betaine and choline content of a whole wheat flour compared to other mill streams. Journal of Cereal Science. 46: 93-95. PMID 19030121 DOI: 10.1016/j.jcs.2006.11.002  0.8
2007 Sanders LM, Zeisel SH. Choline: Dietary Requirements and Role in Brain Development. Nutrition Today. 42: 181-186. PMID 18716669 DOI: 10.1097/01.NT.0000286155.55343.fa  0.8
2007 Chiuve SE, Giovannucci EL, Hankinson SE, Zeisel SH, Dougherty LW, Willett WC, Rimm EB. The association between betaine and choline intakes and the plasma concentrations of homocysteine in women. The American Journal of Clinical Nutrition. 86: 1073-81. PMID 17921386 DOI: 10.1093/Ajcn/86.4.1073  0.8
2007 Zeisel SH. Nutrigenomics and metabolomics will change clinical nutrition and public health practice: insights from studies on dietary requirements for choline. The American Journal of Clinical Nutrition. 86: 542-8. PMID 17823415  0.8
2007 Cho E, Willett WC, Colditz GA, Fuchs CS, Wu K, Chan AT, Zeisel SH, Giovannucci EL. Dietary choline and betaine and the risk of distal colorectal adenoma in women. Journal of the National Cancer Institute. 99: 1224-31. PMID 17686825 DOI: 10.1093/Jnci/Djm082  0.8
2007 Bidulescu A, Chambless LE, Siega-Riz AM, Zeisel SH, Heiss G. Usual choline and betaine dietary intake and incident coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) study. Bmc Cardiovascular Disorders. 7: 20. PMID 17629908 DOI: 10.1186/1471-2261-7-20  0.8
2007 Niculescu MD, da Costa KA, Fischer LM, Zeisel SH. Lymphocyte gene expression in subjects fed a low-choline diet differs between those who develop organ dysfunction and those who do not. The American Journal of Clinical Nutrition. 86: 230-9. PMID 17616785 DOI: 10.1093/Ajcn/86.1.230  0.8
2007 Zeisel SH. Gene response elements, genetic polymorphisms and epigenetics influence the human dietary requirement for choline. Iubmb Life. 59: 380-7. PMID 17613168 DOI: 10.1080/15216540701468954  0.8
2007 Fischer LM, daCosta KA, Kwock L, Stewart PW, Lu TS, Stabler SP, Allen RH, Zeisel SH. Sex and menopausal status influence human dietary requirements for the nutrient choline. The American Journal of Clinical Nutrition. 85: 1275-85. PMID 17490963  0.8
2007 Resseguie M, Song J, Niculescu MD, da Costa KA, Randall TA, Zeisel SH. Phosphatidylethanolamine N-methyltransferase (PEMT) gene expression is induced by estrogen in human and mouse primary hepatocytes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 2622-32. PMID 17456783 DOI: 10.1096/Fj.07-8227Com  0.8
2007 Steck SE, Gammon MD, Hebert JR, Wall DE, Zeisel SH. GSTM1, GSTT1, GSTP1, and GSTA1 polymorphisms and urinary isothiocyanate metabolites following broccoli consumption in humans. The Journal of Nutrition. 137: 904-9. PMID 17374652 DOI: 10.1093/Jn/137.4.904  0.8
2007 Couch M, Lai V, Cannon T, Guttridge D, Zanation A, George J, Hayes DN, Zeisel S, Shores C. Cancer cachexia syndrome in head and neck cancer patients: part I. Diagnosis, impact on quality of life and survival, and treatment. Head & Neck. 29: 401-11. PMID 17285641 DOI: 10.1002/Hed.20447  0.8
2007 Niculescu MD, Wu R, Guo Z, da Costa KA, Zeisel SH. Diethanolamine alters proliferation and choline metabolism in mouse neural precursor cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 96: 321-6. PMID 17204582 DOI: 10.1093/Toxsci/Kfl200  0.8
2007 Niculescu MD, Pop EA, Fischer LM, Zeisel SH. Dietary isoflavones differentially induce gene expression changes in lymphocytes from postmenopausal women who form equol as compared with those who do not. The Journal of Nutritional Biochemistry. 18: 380-90. PMID 16963248 DOI: 10.1016/J.Jnutbio.2006.06.002  0.8
2007 Zeisel SH. Response to: DEA in consumer products is safe [2] Faseb Journal. 21: 296-297. DOI: 10.1096/fj.07-0104ufm  0.8
2006 Zeisel SH. The fetal origins of memory: the role of dietary choline in optimal brain development. The Journal of Pediatrics. 149: S131-6. PMID 17212955 DOI: 10.1016/j.jpeds.2006.06.065  0.8
2006 Craciunescu CN, Wu R, Zeisel SH. Diethanolamine alters neurogenesis and induces apoptosis in fetal mouse hippocampus. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1635-40. PMID 16873886 DOI: 10.1096/fj.06-5978com  0.8
2006 Zeisel SH. Choline: critical role during fetal development and dietary requirements in adults. Annual Review of Nutrition. 26: 229-50. PMID 16848706 DOI: 10.1146/annurev.nutr.26.061505.111156  0.8
2006 da Costa KA, Niculescu MD, Craciunescu CN, Fischer LM, Zeisel SH. Choline deficiency increases lymphocyte apoptosis and DNA damage in humans. The American Journal of Clinical Nutrition. 84: 88-94. PMID 16825685 DOI: 10.1093/Ajcn/84.1.88  0.8
2006 da Costa KA, Kozyreva OG, Song J, Galanko JA, Fischer LM, Zeisel SH. Common genetic polymorphisms affect the human requirement for the nutrient choline. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1336-44. PMID 16816108 DOI: 10.1096/Fj.06-5734Com  0.8
2006 Buist NR, Glenn B, Vugrek O, Wagner C, Stabler S, Allen RH, Pogribny I, Schulze A, Zeisel SH, Barić I, Mudd SH. S-adenosylhomocysteine hydrolase deficiency in a 26-year-old man. Journal of Inherited Metabolic Disease. 29: 538-45. PMID 16736098 DOI: 10.1007/s10545-006-0240-0  0.8
2006 Zeisel SH, Niculescu MD. Perinatal choline influences brain structure and function. Nutrition Reviews. 64: 197-203. PMID 16673755 DOI: 10.1111/J.1753-4887.2006.Tb00202.X  0.8
2006 Lindell KC, Adams KM, Kohlmeier M, Zeisel SH. The evolution of Nutrition in Medicine, a computer-assisted nutrition curriculum. The American Journal of Clinical Nutrition. 83: 956S-962S. PMID 16600955  0.8
2006 Adams KM, Lindell KC, Kohlmeier M, Zeisel SH. Status of nutrition education in medical schools. The American Journal of Clinical Nutrition. 83: 941S-944S. PMID 16600952  0.8
2006 Cho E, Zeisel SH, Jacques P, Selhub J, Dougherty L, Colditz GA, Willett WC. Dietary choline and betaine assessed by food-frequency questionnaire in relation to plasma total homocysteine concentration in the Framingham Offspring Study. The American Journal of Clinical Nutrition. 83: 905-11. PMID 16600945 DOI: 10.1093/Ajcn/83.4.905  0.8
2006 Zeisel SH. Betaine supplementation and blood lipids: fact or artifact? Nutrition Reviews. 64: 77-9. PMID 16536184 DOI: 10.1301/nr.2006.feb.77-79  0.8
2006 Niculescu MD, Craciunescu CN, Zeisel SH. Dietary choline deficiency alters global and gene-specific DNA methylation in the developing hippocampus of mouse fetal brains. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 43-9. PMID 16394266 DOI: 10.1096/Fj.05-4707Com  0.8
2006 Zeisel SH. People with fatty liver are more likely to have the PEMT rs7946 SNP, yet populations with the mutant allele do not have fatty liver [2] Faseb Journal. 20: 2181-2182. DOI: 10.1096/fj.06-1005ufm  0.8
2005 Gossell-Williams M, Fletcher H, McFarlane-Anderson N, Jacob A, Patel J, Zeisel S. Dietary intake of choline and plasma choline concentrations in pregnant women in Jamaica. The West Indian Medical Journal. 54: 355-9. PMID 16642650  0.8
2005 Barić I, Cuk M, Fumić K, Vugrek O, Allen RH, Glenn B, Maradin M, Pazanin L, Pogribny I, Rados M, Sarnavka V, Schulze A, Stabler S, Wagner C, Zeisel SH, et al. S-Adenosylhomocysteine hydrolase deficiency: a second patient, the younger brother of the index patient, and outcomes during therapy. Journal of Inherited Metabolic Disease. 28: 885-902. PMID 16435181 DOI: 10.1007/s10545-005-0192-9  0.8
2005 Wijekoon EP, Hall B, Ratnam S, Brosnan ME, Zeisel SH, Brosnan JT. Homocysteine metabolism in ZDF (type 2) diabetic rats. Diabetes. 54: 3245-51. PMID 16249451 DOI: 10.2337/Diabetes.54.11.3245  0.8
2005 Kohlmeier M, da Costa KA, Fischer LM, Zeisel SH. Genetic variation of folate-mediated one-carbon transfer pathway predicts susceptibility to choline deficiency in humans. Proceedings of the National Academy of Sciences of the United States of America. 102: 16025-30. PMID 16236726 DOI: 10.1073/pnas.0504285102  0.8
2005 Zeisel SH. Choline, homocysteine, and pregnancy. The American Journal of Clinical Nutrition. 82: 719-20. PMID 16210698  0.8
2005 Albright CD, Mar MH, Craciunescu CN, Song J, Zeisel SH. Maternal dietary choline availability alters the balance of netrin-1 and DCC neuronal migration proteins in fetal mouse brain hippocampus. Brain Research. Developmental Brain Research. 159: 149-54. PMID 16109446 DOI: 10.1016/J.Devbrainres.2005.07.002  0.8
2005 Song J, da Costa KA, Fischer LM, Kohlmeier M, Kwock L, Wang S, Zeisel SH. Polymorphism of the PEMT gene and susceptibility to nonalcoholic fatty liver disease (NAFLD). Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1266-71. PMID 16051693 DOI: 10.1096/Fj.04-3580Com  0.8
2005 Zeisel SH, Freake HC, Bauman DE, Bier DM, Burrin DG, German JB, Klein S, Marquis GS, Milner JA, Pelto GH, Rasmussen KM. The nutritional phenotype in the age of metabolomics. The Journal of Nutrition. 135: 1613-6. PMID 15987837 DOI: 10.1093/Jn/135.7.1613  0.8
2005 Niculescu MD, Craciunescu CN, Zeisel SH. Gene expression profiling of choline-deprived neural precursor cells isolated from mouse brain. Brain Research. Molecular Brain Research. 134: 309-22. PMID 15836926 DOI: 10.1016/J.Molbrainres.2004.11.001  0.8
2005 Zhu X, Zeisel SH. Gene expression profiling in phosphatidylethanolamine N-methyltransferase knockout mice. Brain Research. Molecular Brain Research. 134: 239-55. PMID 15836921 DOI: 10.1016/J.Molbrainres.2004.10.040  0.8
2005 Fischer LM, Scearce JA, Mar MH, Patel JR, Blanchard RT, Macintosh BA, Busby MG, Zeisel SH. Ad libitum choline intake in healthy individuals meets or exceeds the proposed adequate intake level. The Journal of Nutrition. 135: 826-9. PMID 15795442  0.8
2005 da Costa KA, Gaffney CE, Fischer LM, Zeisel SH. Choline deficiency in mice and humans is associated with increased plasma homocysteine concentration after a methionine load. The American Journal of Clinical Nutrition. 81: 440-4. PMID 15699233  0.8
2005 Albright CD, da Costa KA, Craciunescu CN, Klem E, Mar MH, Zeisel SH. Regulation of choline deficiency apoptosis by epidermal growth factor in CWSV-1 rat hepatocytes. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 15: 59-68. PMID 15665516 DOI: 10.1159/000083653  0.8
2004 Zeisel SH. Nutritional importance of choline for brain development. Journal of the American College of Nutrition. 23: 621S-626S. PMID 15640516  0.8
2004 Siega-Riz AM, Savitz DA, Zeisel SH, Thorp JM, Herring A. Second trimester folate status and preterm birth. American Journal of Obstetrics and Gynecology. 191: 1851-7. PMID 15592264 DOI: 10.1016/J.Ajog.2004.07.076  0.8
2004 Busby MG, Fischer L, da Costa KA, Thompson D, Mar MH, Zeisel SH. Choline- and betaine-defined diets for use in clinical research and for the management of trimethylaminuria. Journal of the American Dietetic Association. 104: 1836-45. PMID 15565078 DOI: 10.1016/j.jada.2004.09.027  0.8
2004 Zeisel SH. Antioxidants suppress apoptosis. The Journal of Nutrition. 134: 3179S-3180S. PMID 15514296  0.8
2004 German JB, Bauman DE, Burrin DG, Failla ML, Freake HC, King JC, Klein S, Milner JA, Pelto GH, Rasmussen KM, Zeisel SH. Metabolomics in the opening decade of the 21st century: building the roads to individualized health. The Journal of Nutrition. 134: 2729-32. PMID 15465774 DOI: 10.1093/Jn/134.10.2729  0.8
2004 Fischer L, Mahoney C, Jeffcoat AR, Koch MA, Thomas BE, Valentine JL, Stinchcombe T, Boan J, Crowell JA, Zeisel SH. Clinical characteristics and pharmacokinetics of purified soy isoflavones: multiple-dose administration to men with prostate neoplasia. Nutrition and Cancer. 48: 160-70. PMID 15231450 DOI: 10.1207/S15327914Nc4802_5  0.8
2004 da Costa KA, Badea M, Fischer LM, Zeisel SH. Elevated serum creatine phosphokinase in choline-deficient humans: mechanistic studies in C2C12 mouse myoblasts. The American Journal of Clinical Nutrition. 80: 163-70. PMID 15213044  0.8
2004 Niculescu MD, Yamamuro Y, Zeisel SH. Choline availability modulates human neuroblastoma cell proliferation and alters the methylation of the promoter region of the cyclin-dependent kinase inhibitor 3 gene. Journal of Neurochemistry. 89: 1252-9. PMID 15147518 DOI: 10.1111/J.1471-4159.2004.02414.X  0.8
2004 Schwahn BC, Wendel U, Lussier-Cacan S, Mar MH, Zeisel SH, Leclerc D, Castro C, Garrow TA, Rozen R. Effects of betaine in a murine model of mild cystathionine-beta-synthase deficiency. Metabolism: Clinical and Experimental. 53: 594-9. PMID 15131763 DOI: 10.1016/J.Metabol.2003.10.033  0.8
2004 Zhu X, Mar MH, Song J, Zeisel SH. Deletion of the Pemt gene increases progenitor cell mitosis, DNA and protein methylation and decreases calretinin expression in embryonic day 17 mouse hippocampus. Brain Research. Developmental Brain Research. 149: 121-9. PMID 15063092 DOI: 10.1016/J.Devbrainres.2004.01.004  0.8
2004 Stott WT, Radtke BJ, Linscombe VA, Mar MH, Zeisel SH. Evaluation of the potential of triethanolamine to alter hepatic choline levels in female B6C3F1 mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 79: 242-7. PMID 15056812 DOI: 10.1093/toxsci/kfh115  0.8
2004 Baric I, Fumic K, Glenn B, Cuk M, Schulze A, Finkelstein JD, James SJ, Mejaski-Bosnjak V, Pazanin L, Pogribny IP, Rados M, Sarnavka V, Scukanec-Spoljar M, Allen RH, Stabler S, ... ... Zeisel S, et al. S-adenosylhomocysteine hydrolase deficiency in a human: a genetic disorder of methionine metabolism. Proceedings of the National Academy of Sciences of the United States of America. 101: 4234-9. PMID 15024124 DOI: 10.1073/pnas.0400658101  0.8
2004 Craciunescu CN, Brown EC, Mar MH, Albright CD, Nadeau MR, Zeisel SH. Folic acid deficiency during late gestation decreases progenitor cell proliferation and increases apoptosis in fetal mouse brain. The Journal of Nutrition. 134: 162-6. PMID 14704311  0.8
2003 Norman HA, Butrum RR, Feldman E, Heber D, Nixon D, Picciano MF, Rivlin R, Simopoulos A, Wargovich MJ, Weisburger EK, Zeisel SH. The role of dietary supplements during cancer therapy. The Journal of Nutrition. 133: 3794S-3799S. PMID 14608116 DOI: 10.1093/Jn/133.11.3794S  0.8
2003 Craciunescu CN, Albright CD, Mar MH, Song J, Zeisel SH. Choline availability during embryonic development alters progenitor cell mitosis in developing mouse hippocampus. The Journal of Nutrition. 133: 3614-8. PMID 14608083 DOI: 10.1093/Jn/133.11.3614  0.8
2003 Watkins SM, Zhu X, Zeisel SH. Phosphatidylethanolamine-N-methyltransferase activity and dietary choline regulate liver-plasma lipid flux and essential fatty acid metabolism in mice. The Journal of Nutrition. 133: 3386-91. PMID 14608048 DOI: 10.1093/Jn/133.11.3386  0.8
2003 Mudd SH, Tangerman A, Stabler SP, Allen RH, Wagner C, Zeisel SH, Levy HL. Maternal methionine adenosyltransferase I/III deficiency: reproductive outcomes in a woman with four pregnancies. Journal of Inherited Metabolic Disease. 26: 443-58. PMID 14518826 DOI: 10.1023/A:1025121326959  0.8
2003 Zeisel SH, Mar MH, Howe JC, Holden JM. Concentrations of choline-containing compounds and betaine in common foods. The Journal of Nutrition. 133: 1302-7. PMID 12730414  0.8
2003 Albright CD, Siwek DF, Craciunescu CN, Mar MH, Kowall NW, Williams CL, Zeisel SH. Choline availability during embryonic development alters the localization of calretinin in developing and aging mouse hippocampus. Nutritional Neuroscience. 6: 129-34. PMID 12722989 DOI: 10.1080/1028415031000084418  0.8
2003 Albright CD, Salganik RI, Craciunescu CN, Mar MH, Zeisel SH. Mitochondrial and microsomal derived reactive oxygen species mediate apoptosis induced by transforming growth factor-beta1 in immortalized rat hepatocytes. Journal of Cellular Biochemistry. 89: 254-61. PMID 12704789 DOI: 10.1002/jcb.10498  0.8
2003 Kohlmeier M, McConathy WJ, Cooksey Lindell K, Zeisel SH. Adapting the contents of computer-based instruction based on knowledge tests maintains effectiveness of nutrition education. The American Journal of Clinical Nutrition. 77: 1025S-1027S. PMID 12663312  0.8
2003 Miltyk W, Craciunescu CN, Fischer L, Jeffcoat RA, Koch MA, Lopaczynski W, Mahoney C, Jeffcoat RA, Crowell J, Paglieri J, Zeisel SH. Lack of significant genotoxicity of purified soy isoflavones (genistein, daidzein, and glycitein) in 20 patients with prostate cancer. The American Journal of Clinical Nutrition. 77: 875-82. PMID 12663286  0.8
2003 Schwahn BC, Chen Z, Laryea MD, Wendel U, Lussier-Cacan S, Genest J, Mar MH, Zeisel SH, Castro C, Garrow T, Rozen R. Homocysteine-betaine interactions in a murine model of 5,10-methylenetetrahydrofolate reductase deficiency. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 512-4. PMID 12551843 DOI: 10.1096/Fj.02-0456Fje  0.8
2003 Zhu X, Song J, Mar MH, Edwards LJ, Zeisel SH. Phosphatidylethanolamine N-methyltransferase (PEMT) knockout mice have hepatic steatosis and abnormal hepatic choline metabolite concentrations despite ingesting a recommended dietary intake of choline. The Biochemical Journal. 370: 987-93. PMID 12466019 DOI: 10.1042/Bj20021523  0.8
2002 Bloedon LT, Jeffcoat AR, Lopaczynski W, Schell MJ, Black TM, Dix KJ, Thomas BF, Albright C, Busby MG, Crowell JA, Zeisel SH. Safety and pharmacokinetics of purified soy isoflavones: single-dose administration to postmenopausal women. The American Journal of Clinical Nutrition. 76: 1126-37. PMID 12399289 DOI: 10.1093/Ajcn/76.5.1126  0.8
2002 Koc H, Mar MH, Ranasinghe A, Swenberg JA, Zeisel SH. Quantitation of choline and its metabolites in tissues and foods by liquid chromatography/electrospray ionization-isotope dilution mass spectrometry. Analytical Chemistry. 74: 4734-40. PMID 12349977 DOI: 10.1021/Ac025624X  0.8
2002 Niculescu MD, Zeisel SH. Diet, methyl donors and DNA methylation: interactions between dietary folate, methionine and choline. The Journal of Nutrition. 132: 2333S-2335S. PMID 12163687 DOI: 10.1093/Jn/132.8.2333S  0.8
2002 Yen CL, Mar MH, Craciunescu CN, Edwards LJ, Zeisel SH. Deficiency in methionine, tryptophan, isoleucine, or choline induces apoptosis in cultured cells. The Journal of Nutrition. 132: 1840-7. PMID 12097657 DOI: 10.1093/Jn/132.7.1840  0.8
2002 Cottington EM, LaMantia C, Stabler SP, Allen RH, Tangerman A, Wagner C, Zeisel SH, Mudd SH. Adverse event associated with methionine loading test: a case report. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 1046-50. PMID 12067919 DOI: 10.1161/01.Atv.0000020400.25088.A7  0.8
2002 Lehman-McKeeman LD, Gamsky EA, Hicks SM, Vassallo JD, Mar MH, Zeisel SH. Diethanolamine induces hepatic choline deficiency in mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 67: 38-45. PMID 11961214 DOI: 10.1093/Toxsci/67.1.38  0.8
2002 Fisher MC, Zeisel SH, Mar MH, Sadler TW. Perturbations in choline metabolism cause neural tube defects in mouse embryos in vitro. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 619-21. PMID 11919173  0.8
2002 Buchowski MS, Plaisted C, Fort J, Zeisel SH. Computer-assisted teaching of nutritional anemias and diabetes to first-year medical students. The American Journal of Clinical Nutrition. 75: 154-61. PMID 11756073  0.8
2002 Busby MG, Jeffcoat AR, Bloedon LT, Koch MA, Black T, Dix KJ, Heizer WD, Thomas BF, Hill JM, Crowell JA, Zeisel SH. Clinical characteristics and pharmacokinetics of purified soy isoflavones: single-dose administration to healthy men. The American Journal of Clinical Nutrition. 75: 126-36. PMID 11756070 DOI: 10.1093/Ajcn/75.1.126  0.8
2001 Thomas BF, Zeisel SH, Busby MG, Hill JM, Mitchell RA, Scheffler NM, Brown SS, Bloeden LT, Dix KJ, Jeffcoat AR. Quantitative analysis of the principle soy isoflavones genistein, daidzein and glycitein, and their primary conjugated metabolites in human plasma and urine using reversed-phase high-performance liquid chromatography with ultraviolet detection. Journal of Chromatography. B, Biomedical Sciences and Applications. 760: 191-205. PMID 11530977 DOI: 10.1016/S0378-4347(01)00269-9  0.8
2001 Albright CD, Mar MH, Friedrich CB, Brown EC, Zeisel SH. Maternal choline availability alters the localization of p15Ink4B and p27Kip1 cyclin-dependent kinase inhibitors in the developing fetal rat brain hippocampus. Developmental Neuroscience. 23: 100-6. PMID 11509832 DOI: 10.1159/000048701  0.8
2001 Holmes-McNary MQ, Baldwin AS, Zeisel SH. Opposing regulation of choline deficiency-induced apoptosis by p53 and nuclear factor kappaB. The Journal of Biological Chemistry. 276: 41197-204. PMID 11483591 DOI: 10.1074/Jbc.M010936200  0.8
2001 Vrablic AS, Albright CD, Craciunescu CN, Salganik RI, Zeisel SH. Altered mitochondrial function and overgeneration of reactive oxygen species precede the induction of apoptosis by 1-O-octadecyl-2-methyl-rac-glycero-3-phosphocholine in p53-defective hepatocytes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 1739-44. PMID 11481221 DOI: 10.1096/fj.00-0300com  0.8
2001 Yen CL, Mar MH, Meeker RB, Fernandes A, Zeisel SH. Choline deficiency induces apoptosis in primary cultures of fetal neurons. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 1704-10. PMID 11481217 DOI: 10.1096/Fj.00-0800Com  0.8
2001 Fisher MC, Zeisel SH, Mar MH, Sadler TW. Septo-optic dysplasia as a manifestation of valproic acid embryopathy Teratology. 64: 83-86. PMID 11460259 DOI: 10.1002/tera.1049  0.8
2001 Papas A, Vos E, Zeisel S. Vitamin E, cancer, and apoptosis [1] American Journal of Clinical Nutrition. 73: 1113-1114. PMID 11382669  0.8
2001 Zeisel SH, Allen LH, Coburn SP, Erdman JW, Failla ML, Freake HC, King JC, Storch J. Nutrition: a reservoir for integrative science. The Journal of Nutrition. 131: 1319-21. PMID 11285344 DOI: 10.1093/Jn/131.4.1319  0.8
2001 Lopaczynski W, Zeisel SH. Antioxidants, programmed cell death, and cancer Nutrition Research. 21: 295-307. DOI: 10.1016/S0271-5317(00)00288-8  0.8
2000 Zeisel SH. Choline: needed for normal development of memory. Journal of the American College of Nutrition. 19: 528S-531S. PMID 11023003  0.8
2000 Plaisted CS, Kohlmeier M, Cooksey K, Zeisel SH. The development of "Nutrition in Medicine" interactive CD-ROM programs for medical nutrition education. Journal of Cancer Education : the Official Journal of the American Association For Cancer Education. 15: 140-3. PMID 11019760 DOI: 10.1080/08858190009528681  0.8
2000 Cooksey K, Kohlmeier M, Plaisted C, Adams K, Zeisel SH. Development of a case-based integrated nutrition curriculum for medical students 1-4 American Journal of Clinical Nutrition. 72: 890S-897S. PMID 10966918  0.8
2000 Cooksey K, Kohlmeier M, Plaisted C, Adams K, Zeisel SH. Getting nutrition education into medical schools: a computer-based approach. The American Journal of Clinical Nutrition. 72: 868S-76S. PMID 10966915  0.8
2000 Zeisel SH. Is there a metabolic basis for dietary supplementation? The American Journal of Clinical Nutrition. 72: 507S-11S. PMID 10919952  0.8
2000 Hambraeus L, Tylleskär T, Zeisel S, Kollberg H, Fagerlund A. [Nutrition in a new millennium. IT--for integrated teaching]. Lã¤Kartidningen. 97: 2496. PMID 10909227  0.8
2000 Zeisel SH. Choline: an essential nutrient for humans. Nutrition (Burbank, Los Angeles County, Calif.). 16: 669-71. PMID 10906592 DOI: 10.1016/S0899-9007(00)00349-X  0.8
2000 Warber JP, Patton JF, Tharion WJ, Zeisel SH, Mello RP, Kemnitz CP, Lieberman HR. The effects of choline supplementation on physical performance. International Journal of Sport Nutrition and Exercise Metabolism. 10: 170-81. PMID 10861337  0.8
2000 Salganik RI, Albright CD, Rodgers J, Kim J, Zeisel SH, Sivashinskiy MS, Van Dyke TA. Dietary antioxidant depletion: enhancement of tumor apoptosis and inhibition of brain tumor growth in transgenic mice. Carcinogenesis. 21: 909-14. PMID 10783311  0.8
2000 Kohlmeier M, Althouse L, Stritter F, Zeisel SH. Introducing cancer nutrition to medical students: effectiveness of computer-based instruction. The American Journal of Clinical Nutrition. 71: 873-7. PMID 10731491  0.8
2000 Stott WT, Bartels MJ, Brzak KA, Mar M, Markham DA, Thornton CM, Zeisel SH. Potential mechanisms of tumorigenic action of diethanolamine in mice. Toxicology Letters. 114: 67-75. PMID 10713470 DOI: 10.1016/S0378-4274(99)00197-6  0.8
2000 Zeisel SH. What is the role for nutrition in medical education and research? Scandinavian Journal of Nutrition/Naringsforskning. 44: 61-63.  0.8
1999 Mar MH, Zeisel SH. Betaine in wine: answer to the French paradox? Medical Hypotheses. 53: 383-5. PMID 10616037 DOI: 10.1054/mehy.1998.0791  0.8
1999 Curry M, Hazard-Daniel A, Daniel HJ, Zeisel SH. Nutraceuticals [4] Science. 286: 1854-1855. PMID 10610573  0.8
1999 Albright CD, Friedrich CB, Brown EC, Mar MH, Zeisel SH. Maternal dietary choline availability alters mitosis, apoptosis and the localization of TOAD-64 protein in the developing fetal rat septum. Brain Research. Developmental Brain Research. 115: 123-9. PMID 10407130 DOI: 10.1016/S0165-3806(99)00057-7  0.8
1999 Albright CD, Tsai AY, Friedrich CB, Mar MH, Zeisel SH. Choline availability alters embryonic development of the hippocampus and septum in the rat. Brain Research. Developmental Brain Research. 113: 13-20. PMID 10064869 DOI: 10.1016/S0165-3806(98)00183-7  0.8
1999 Yen CL, Mar MH, Zeisel SH. Choline deficiency-induced apoptosis in PC12 cells is associated with diminished membrane phosphatidylcholine and sphingomyelin, accumulation of ceramide and diacylglycerol, and activation of a caspase. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 13: 135-42. PMID 9872938  0.8
1998 Albright CD, Tsai AY, Mar MH, Zeisel SH. Choline availability modulates the expression of TGFbeta1 and cytoskeletal proteins in the hippocampus of developing rat brain. Neurochemical Research. 23: 751-8. PMID 9566615 DOI: 10.1023/A:1022411510636  0.8
1997 Holmes-McNary MQ, Loy R, Mar MH, Albright CD, Zeisel SH. Apoptosis is induced by choline deficiency in fetal brain and in PC12 cells. Brain Research. Developmental Brain Research. 101: 9-16. PMID 9263575 DOI: 10.1016/S0165-3806(97)00044-8  0.8
1997 Chernoff R, Bruner D, Fitz P, Gannon J, Glade M, Hausman P, Howell WH, Jensen G, Stallings V, Wallach S, Zeisel S. Credentials available in human clinical nutrition: a report of the Intersociety Committee on Nutrition Certification. The American Journal of Clinical Nutrition. 65: 1562-6. PMID 9157790 DOI: 10.1093/Ajcn/65.5.1562  0.8
1997 Chernoff R, Bruner D, Fitz P, Gannon J, Glade M, Hansman P, Howell WH, Jensen G, Stallings V, Wallach S, Zeisel S. Credentials available in human clinical nutrition: a report of the Intersociety Committee on Nutrition Certification. Journal of the American College of Nutrition. 16: 184-8. PMID 9100221 DOI: 10.1080/07315724.1997.10718671  0.8
1997 Shin OH, Mar MH, Albright CD, Citarella MT, da Costa KA, Zeisel SH. Methyl-group donors cannot prevent apoptotic death of rat hepatocytes induced by choline-deficiency. Journal of Cellular Biochemistry. 64: 196-208. PMID 9027580 DOI: 10.1002/(SICI)1097-4644(199702)64:2<196::AID-JCB3>3.0.CO;2-S  0.8
1997 Donovan SM, Mar MH, Zeisel SH. Choline and choline ester concentrations in porcine milk throughout lactation Journal of Nutritional Biochemistry. 8: 603-607. DOI: 10.1016/S0955-2863(97)00115-0  0.8
1996 Albright CD, Liu R, Bethea TC, Da Costa KA, Salganik RI, Zeisel SH. Choline deficiency induces apoptosis in SV40-immortalized CWSV-1 rat hepatocytes in culture. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 10: 510-6. PMID 8647350  0.8
1995 Brotschi EA, Hilbinger CL, Kahl EA, Vaules WA, Midis NA, Blusztajn JK, Zeisel SH. Radioactive choline metabolism in guinea pig gallbladder. Is there measurable acetylcholine release? Digestive Diseases and Sciences. 40: 1982-9. PMID 7555453 DOI: 10.1007/BF02208667  0.8
1995 Garner SC, Mar MH, Zeisel SH. Choline distribution and metabolism in pregnant rats and fetuses are influenced by the choline content of the maternal diet. The Journal of Nutrition. 125: 2851-8. PMID 7472666  0.8
1994 Zeisel SH, Blusztajn JK. Choline and human nutrition. Annual Review of Nutrition. 14: 269-96. PMID 7946521 DOI: 10.1146/Annurev.Nu.14.070194.001413  0.8
1993 da Costa KA, Cochary EF, Blusztajn JK, Garner SC, Zeisel SH. Accumulation of 1,2-sn-diradylglycerol with increased membrane-associated protein kinase C may be the mechanism for spontaneous hepatocarcinogenesis in choline-deficient rats. The Journal of Biological Chemistry. 268: 2100-5. PMID 8420980  0.8
1993 Rohlfs EM, Garner SC, Mar MH, Zeisel SH. Glycerophosphocholine and phosphocholine are the major choline metabolites in rat milk. The Journal of Nutrition. 123: 1762-8. PMID 8410369  0.8
1993 Rogers AE, Zeisel SH, Groopman J. Diet and carcinogenesis. Carcinogenesis. 14: 2205-17. PMID 8242845 DOI: 10.1093/Carcin/14.11.2205  0.8
1992 Zhang J, Blusztajn JK, Zeisel SH. Measurement of the formation of betaine aldehyde and betaine in rat liver mitochondria by a high pressure liquid chromatography-radioenzymatic assay. Biochimica Et Biophysica Acta. 1117: 333-9. PMID 1420283  0.72
1992 Varela-Moreiras G, Selhub J, daCosta KA, Zeisel SH. Effect of chronic choline deficiency in rats on liver folate content and distribution The Journal of Nutritional Biochemistry. 3: 519-522. DOI: 10.1016/0955-2863(92)90073-R  0.8
1991 Zeisel SH, Da Costa KA, Franklin PD, Alexander EA, Lamont JT, Sheard NF, Beiser A. Choline, an essential nutrient for humans. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 5: 2093-8. PMID 2010061  0.8
1990 Pomfret EA, daCosta KA, Zeisel SH. Effects of choline deficiency and methotrexate treatment upon rat liver. The Journal of Nutritional Biochemistry. 1: 533-41. PMID 15539171 DOI: 10.1016/0955-2863(90)90039-N  0.8
1990 Zeisel SH, daCosta KA. Choline: determination using gas chromatography/mass spectrometry. The Journal of Nutritional Biochemistry. 1: 55-9. PMID 15539166 DOI: 10.1016/0955-2863(90)90101-P  0.8
1990 daCosta KA, Vrbanac JJ, Zeisel SH. The measurement of dimethylamine, trimethylamine, and trimethylamine N-oxide using capillary gas chromatography-mass spectrometry. Analytical Biochemistry. 187: 234-9. PMID 2382825 DOI: 10.1016/0003-2697(90)90449-J  0.8
1990 Gelenberg AJ, Wojcik JD, Falk WE, Baldessarini RJ, Zeisel SH, Schoenfeld D, Mok GS. Tyrosine for depression: a double-blind trial. Journal of Affective Disorders. 19: 125-32. PMID 2142699 DOI: 10.1016/0165-0327(90)90017-3  0.8
1989 Blusztajn JK, Zeisel SH. 1,2-sn-diacylglycerol accumulates in choline-deficient liver. A possible mechanism of hepatic carcinogenesis via alteration in protein kinase C activity? Febs Letters. 243: 267-70. PMID 2917651 DOI: 10.1016/0014-5793(89)80142-5  0.8
1989 Pomfret EA, daCosta KA, Schurman LL, Zeisel SH. Measurement of choline and choline metabolite concentrations using high-pressure liquid chromatography and gas chromatography-mass spectrometry. Analytical Biochemistry. 180: 85-90. PMID 2817347 DOI: 10.1016/0003-2697(89)90091-2  0.8
1989 Zeisel SH, Zola T, daCosta KA, Pomfret EA. Effect of choline deficiency on S-adenosylmethionine and methionine concentrations in rat liver. The Biochemical Journal. 259: 725-9. PMID 2730584  0.8
1989 Zeisel SH, daCosta KA, Youssef M, Hensey S. Conversion of dietary choline to trimethylamine and dimethylamine in rats: dose-response relationship. The Journal of Nutrition. 119: 800-4. PMID 2723829  0.8
1988 Zeisel SH, daCosta KA, LaMont JT. Mono-, di- and trimethylamine in human gastric fluid: potential substrates for nitrosodimethylamine formation. Carcinogenesis. 9: 179-81. PMID 3335043 DOI: 10.1093/carcin/9.1.179  0.8
1988 Oh SK, Ross S, Walker J, Zeisel S. Role of a SER immune suppressor in immune surveillance. Immunology. 64: 73-9. PMID 3260218  0.8
1988 Yang EK, Blusztajn JK, Pomfret EA, Zeisel SH. Rat and human mammary tissue can synthesize choline moiety via the methylation of phosphatidylethanolamine. The Biochemical Journal. 256: 821-8. PMID 3223955 DOI: 10.1042/Bj2560821  0.8
1987 Zeisel SH, Ellis AL, Sun XF, Pomfret EA, Ting BT, Janghorbani M. Dose-response relations in urinary excretion of trimethylselenonium in the rat. The Journal of Nutrition. 117: 1609-14. PMID 3655939  0.8
1986 Zeisel SH, DaCosta KA. Increase in human exposure to methylamine precursors of N-nitrosamines after eating fish. Cancer Research. 46: 6136-8. PMID 3779634  0.8
1986 Zeisel SH, DaCosta KA, Edrise BM, Fox JG. Transport of dimethylamine, a precursor of nitrosodimethylamine, into stomach of ferret and dog. Carcinogenesis. 7: 775-8. PMID 3698205 DOI: 10.1093/carcin/7.5.775  0.8
1985 Blusztajn JK, Zeisel SH, Wurtman RJ. Developmental changes in the activity of phosphatidylethanolamine N-methyltransferases in rat brain. The Biochemical Journal. 232: 505-11. PMID 4091805 DOI: 10.1042/Bj2320505  0.8
1985 Zeisel SH, DaCosta KA, Fox JG. Endogenous formation of dimethylamine. The Biochemical Journal. 232: 403-8. PMID 4091797  0.8
1983 Zeisel SH, Wishnok JS, Blusztajn JK. Formation of methylamines from ingested choline and lecithin. The Journal of Pharmacology and Experimental Therapeutics. 225: 320-4. PMID 6842395  0.8
1982 Zeisel SH, Stanbury JB, Wurtman RJ, Brigida M, Fierro-Benitez R. Choline content of mothers' milk in Ecuador and Boston. The New England Journal of Medicine. 306: 175-6. PMID 7054668  0.8
1982 Conlay LA, Zeisel SH. Neurotransmitter precursors and brain function. Neurosurgery. 10: 524-9. PMID 6124895  0.8
1982 Reinstein D, Corkin S, Growdon JH, Wurtman RJ, Zeisel SH. The second meeting of the international study group on the pharmacology of memory disorders associated with aging (ISG) Neuropsychologia. 20: 225-226. DOI: 10.1016/0028-3932(82)90015-X  0.8
1981 Zeisel S, Reinstein D, Corkin S, Growdon J, Wurtman R. Cholinergic neurones and memory. Nature. 293: 187-8. PMID 7278975 DOI: 10.1038/293187a0  0.8
1981 Magil SG, Zeisel SH, Wurtman RJ. Effects of ingesting soy or egg lecithins on serum choline, brain choline and brain acetylcholine. The Journal of Nutrition. 111: 166-70. PMID 7192727 DOI: 10.1093/Jn/111.1.166  0.8
1981 Zeisel SH, Wurtman RJ. Developmental changes in rat blood choline concentration. The Biochemical Journal. 198: 565-70. PMID 7034731 DOI: 10.1042/BJ1980565  0.8
1981 Zeisel SH, Mauron C, Watkins CJ, Wurtman RJ. Developmental changes in brain indoles, serum tryptophan and other serum neutral amino acids in the rat. Brain Research. 227: 551-64. PMID 6167336 DOI: 10.1016/0165-3806(81)90008-0  0.8
1981 Wurtman RJ, Growdon JH, Corkin S, Reinstein D, Zeisel S. Meeting report Neurobiology of Aging. 2: 149-151.  0.8
1980 Zeisel SH, Epstein MF, Wurtman RJ. Elevated choline concentration in neonatal plasma. Life Sciences. 26: 1827-31. PMID 7392816 DOI: 10.1016/0024-3205(80)90585-8  0.8
1980 Zeisel SH, Growdon JH, Wurtman RJ, Magil SG, Logue M. Normal plasma choline responses to ingested lecithin. Neurology. 30: 1226-9. PMID 7191517 DOI: 10.1212/WNL.30.11.1226  0.8
1980 Zeisel SH, Gelenberg AJ, Growdon JH, Wurtman RJ. Use of choline and lecithin in the treatment of tardive dyskinesia. Advances in Biochemical Psychopharmacology. 24: 463-70. PMID 6996444  0.8
1980 Zeisel SH, Story DL, Wurtman RJ, Brunengraber H. Uptake of free choline by isolated perfused rat liver. Proceedings of the National Academy of Sciences of the United States of America. 77: 4417-9. PMID 6933493 DOI: 10.1073/pnas.77.8.4417  0.8
1980 Zeisel SH, Milunsky A, Blusztajn JK. Prenatal diagnosis of neural tube defects. V. The value of amniotic fluid cholinesterase studies. American Journal of Obstetrics and Gynecology. 137: 481-5. PMID 6155784  0.8
1979 Blusztajn JK, Zeisel SH, Wurtman RJ. Synthesis of lecithin (phosphatidylcholine) from phosphatidylethanolamine in bovine brain. Brain Research. 179: 319-27. PMID 509240 DOI: 10.1016/0006-8993(79)90447-5  0.8
1979 Milunsky A, Blusztajn JK, Zeisel SH. Amniotic-fluid total cholinesterase and neural-tube defects. Lancet. 2: 36. PMID 87905  0.72
1978 Zeisel SH, Millington WR. Free and choline assay. The American Journal of Clinical Nutrition. 31: 1978-81. PMID 717268  0.8
Show low-probability matches.