Indrapal N. Singh - Related publications

Affiliations: 
2002-2006 Anatomy & Neurobiology University of Kentucky College of Medicine, Lexington, KY, United States 
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Montilla A, Ruiz A, Marquez M, Sierra A, Matute C, Domercq M. Role of Mitochondrial Dynamics in Microglial Activation and Metabolic Switch. Immunohorizons. 5: 615-626. PMID 34376483 DOI: 10.4049/immunohorizons.2100068   
2021 Ahluwalia M, Kumar M, Ahluwalia P, Rahimi S, Vender JR, Raju RP, Hess DC, Baban B, Vale FL, Dhandapani KM, Vaibhav K. Rescuing mitochondria in traumatic brain injury and intracerebral hemorrhages - A potential therapeutic approach. Neurochemistry International. 105192. PMID 34560175 DOI: 10.1016/j.neuint.2021.105192   
2021 Zhong Y, Qi A, Liu L, Huang Q, Zhang J, Cai K, Cai C. Shikonin attenuates HO-induced oxidative injury in HT29 cells via antioxidant activities and the inhibition of mitochondrial pathway-mediated apoptosis. Experimental and Therapeutic Medicine. 22: 1118. PMID 34504572 DOI: 10.3892/etm.2021.10552   
2021 Zhang X, Liang S, Gao X, Huang H, Lao F, Dai X. Protective Effect of Chitosan Oligosaccharide against Hydrogen Peroxide-Mediated Oxidative Damage and Cell Apoptosis via Activating Nrf2/ARE Signaling Pathway. Neurotoxicity Research. PMID 34622385 DOI: 10.1007/s12640-021-00419-w   
2021 Wang H, Ai J, Shopit A, Niu M, Ahmed N, Tesfaldet T, Tang Z, Li X, Jamalat Y, Chu P, Peng J, Ma X, Qaed E, Han G, Zhang W, et al. Protection of pancreatic β-cell by phosphocreatine through mitochondrial improvement via the regulation of dual AKT/IRS-1/GSK-3β and STAT3/Cyp-D signaling pathways. Cell Biology and Toxicology. PMID 34455488 DOI: 10.1007/s10565-021-09644-7   
2021 Chen Y, Tang Y, Luo S, Jia H, Xu Q, Chang R, Dong Z, Gao S, Song Q, Dong H, Wang X, Li Z, Aboragah A, Loor JJ, Xu C, et al. Nuclear factor erythroid 2-related factor 2 protects bovine mammary epithelial cells against free fatty acid-induced mitochondrial dysfunction in vitro. Journal of Dairy Science. PMID 34538488 DOI: 10.3168/jds.2021-20732   
2021 Wang Y, Wen J, Almoiliqy M, Wang Y, Liu Z, Yang X, Lu X, Meng Q, Peng J, Lin Y, Sun P. Sesamin Protects against and Ameliorates Rat Intestinal Ischemia/Reperfusion Injury with Involvement of Activating Nrf2/HO-1/NQO1 Signaling Pathway. Oxidative Medicine and Cellular Longevity. 2021: 5147069. PMID 34630849 DOI: 10.1155/2021/5147069   
2021 Yeh JN, Yue Y, Chu YC, Huang CR, Yang CC, Chiang JY, Yip HK, Guo J. Entresto protected the cardiomyocytes and preserved heart function in cardiorenal syndrome rat fed with high-protein diet through regulating the oxidative stress and Mfn2-mediated mitochondrial functional integrity. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 144: 112244. PMID 34601193 DOI: 10.1016/j.biopha.2021.112244   
2021 Ansari F, Yoval B, Niatsetskaya Z, Sosunov S, Stepanova A, Garcia C, Owusu-Ansah E, Ten V, Wittig I, Galkin A. Quantification of NADH:ubiquinone oxidoreductase (complex I) content in biological samples. The Journal of Biological Chemistry. 101204. PMID 34543622 DOI: 10.1016/j.jbc.2021.101204   
2021 Shi W, An L, Zhang J, Li J. extract ameliorates lipopolysaccharide-induced liver injury by improving mitochondrial dysfunction via the AMPK/PGC-1α signaling pathway. Experimental and Therapeutic Medicine. 22: 1138. PMID 34504584 DOI: 10.3892/etm.2021.10572   
2021 Clough E, Chean KT, Inigo J, Tubbesing KE, Chandra D, Chaves L, Reynolds JL, Aalinkeel R, Schwartz SA, Khmaladze A, Mahajan SD. Mitochondrial Dynamics in SARS-COV2 Spike Protein Treated Human Microglia: Implications for Neuro-COVID. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 34599743 DOI: 10.1007/s11481-021-10015-6   
2021 Li L, Liu S, Zhou Y, Zhao M, Wang Y, Wang C, Lou P, Huang R, Ma L, Lu Y, Fu P, Liu J. Indispensable role of mitochondria in maintaining the therapeutic potential of curcumin in acute kidney injury. Journal of Cellular and Molecular Medicine. PMID 34532973 DOI: 10.1111/jcmm.16934   
2021 Xia A, Huang H, You W, Liu Y, Wu H, Liu S. The neuroprotection of hyperbaric oxygen therapy against traumatic brain injury via NF-κB/MAPKs-CXCL1 signaling pathways. Experimental Brain Research. PMID 34687331 DOI: 10.1007/s00221-021-06249-8   
2021 Zhang Y, Li C, Pei Y, Zheng L, Sun X, Zhao Z, Wang S. Trelagliptin ameliorates oxygen-glucose deprivation/reperfusion (OGD/R)-induced mitochondrial dysfunction and metabolic disturbance of endothelial cells. Human Cell. PMID 34435315 DOI: 10.1007/s13577-021-00594-0   
2021 Sharma RK, Singh M, Ghimeray K, Juneja P, Dev G, Pulavarthi S, Reddy SR, Akundi RS. Imidazopyridazine Acetylcholinesterase Inhibitors Display Potent Anti-Proliferative Effects in the Human Neuroblastoma Cell-Line, IMR-32. Molecules (Basel, Switzerland). 26. PMID 34500749 DOI: 10.3390/molecules26175319   
2021 Ma H, Hao J, Liu H, Yin J, Qiang M, Liu M, He S, Zeng D, Liu X, Lian C, Gao Y. Peoniflorin Preconditioning Protects Against Myocardial Ischemia/Reperfusion Injury Through Inhibiting Myocardial Apoptosis: RISK Pathway Involved. Applied Biochemistry and Biotechnology. PMID 34596828 DOI: 10.1007/s12010-021-03680-z   
2021 Janssen L, Ai X, Zheng X, Wei W, Caglayan AB, Kilic E, Wang YC, Hermann DM, Venkataramani V, Bähr M, Doeppner TR. Inhibition of Fatty Acid Synthesis Aggravates Brain Injury, Reduces Blood-Brain Barrier Integrity and Impairs Neurological Recovery in a Murine Stroke Model. Frontiers in Cellular Neuroscience. 15: 733973. PMID 34483846 DOI: 10.3389/fncel.2021.733973   
2021 Mousavi K, Niknahad H, Li H, Jia Z, Manthari RK, Zhao Y, Shi X, Chen Y, Ahmadi A, Azarpira N, Khalvati B, Ommati MM, Heidari R. The activation of nuclear factor-E2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) signaling blunts cholestasis-induced liver and kidney injury. Toxicology Research. 10: 911-927. PMID 34484683 DOI: 10.1093/toxres/tfab073   
2021 Jiang Y, Gu C, Xu H, Shi F, Zhang X, Wang F. iKeap1 activates Nrf2 signaling to protect myocardial cells from oxygen glucose deprivation/re-oxygenation-induced oxidative injury. Biochemical and Biophysical Research Communications. 574: 110-117. PMID 34461498 DOI: 10.1016/j.bbrc.2021.08.024   
2021 Liu C, Jia Y, Qiu Y. Ethyl Acetate Fraction of (L.) Medic Flowers Exerts Inhibitory Effects Against Oxidative Stress in HO-Induced HepG2 Cells and D-Galactose-Induced Aging Mice. Journal of Medicinal Food. 24: 997-1009. PMID 34524027 DOI: 10.1089/jmf.2021.K.0053   
2021 Hu K, Xiao L, Li L, Shen Y, Yang Y, Huang J, Wang Y, Zhang L, Wen S, Tang L. The mitochondria-targeting antioxidant MitoQ alleviated Lipopolysaccharide/ D-galactosamine-induced acute liver injury in mice. Immunology Letters. PMID 34525396 DOI: 10.1016/j.imlet.2021.09.003   
2021 Choi W, Baik KY, Jeong S, Park S, Kim JE, Kim HB, Chung JH. Photobiomodulation as an antioxidant substitute in post-thawing trauma of human stem cells from the apical papilla. Scientific Reports. 11: 17329. PMID 34462607 DOI: 10.1038/s41598-021-96841-3   
2021 Huang C, Santofimia-Castaño P, Liu X, Xia Y, Peng L, Gotorbe C, Neira JL, Tang D, Pouyssegur J, Iovanna J. NUPR1 inhibitor ZZW-115 induces ferroptosis in a mitochondria-dependent manner. Cell Death Discovery. 7: 269. PMID 34599149 DOI: 10.1038/s41420-021-00662-2   
2021 Beyer AM, Norwood Toro LE, Hughes WE, Young M, Clough AV, Gao F, Medhora M, Audi SH, Jacobs ER. Autophagy, TERT, and mitochondrial dysfunction in hyperoxia. American Journal of Physiology. Heart and Circulatory Physiology. PMID 34559580 DOI: 10.1152/ajpheart.00166.2021   
2021 Ramachandran A, Umbaugh DS, Jaeschke H. Mitochondrial Dynamics in Drug-Induced Liver Injury. Livers. 1: 102-115. PMID 34485975 DOI: 10.3390/livers1030010   
2021 Weng Y, Li H, Gao L, Guo W, Xu S, Li L. PER2 Regulates Reactive Oxygen Species Production in the Circadian Susceptibility to Ischemia/Reperfusion Injury in the Heart. Oxidative Medicine and Cellular Longevity. 2021: 6256399. PMID 34659637 DOI: 10.1155/2021/6256399   
2021 Zhang J, Chen S, Li Y, Xiao W, An W. Alleviation of CCCP injury by Augmenter of liver regeneration via the PINK1/Parkin pathway-dependent mitophagy. Experimental Cell Research. 112866. PMID 34655600 DOI: 10.1016/j.yexcr.2021.112866   
2021 Liu Z, Yang B. CTRP6(C1q/Tumor Necrosis Factor (TNF)-related protein-6) alleviated the sevoflurane induced injury of mice central nervous system by promoting the expression of p-Akt (phosphorylated Akt). Bioengineered. 12: 5716-5726. PMID 34516328 DOI: 10.1080/21655979.2021.1967838   
2021 Esselun C, Theyssen E, Eckert GP. Effects of Urolithin A on Mitochondrial Parameters in a Cellular Model of Early Alzheimer Disease. International Journal of Molecular Sciences. 22. PMID 34361099 DOI: 10.3390/ijms22158333   
2021 Chao TY, Hsieh CC, Kuo YH, Yu YJ, Wan CH, Hsieh SC. Bracteanolide A abrogates oxidative stress-induced cellular damage and protects against hepatic ischemia and reperfusion injury in rats. Food Science & Nutrition. 9: 4758-4769. PMID 34531989 DOI: 10.1002/fsn3.2374   
2021 Mi L, Zhang N, Wan J, Cheng M, Liao J, Zheng X. Remote ischemic post‑conditioning alleviates ischemia/reperfusion‑induced intestinal injury via the ERK signaling pathway‑mediated RAGE/HMGB axis. Molecular Medicine Reports. 24. PMID 34490475 DOI: 10.3892/mmr.2021.12413   
2021 Willson JA, Arienti S, Sadiku P, Reyes L, Coelho P, Morrison T, Rinaldi G, Dockrell DH, Whyte MKB, Walmsley SR. Neutrophil HIF-1α stabilisation is augmented by mitochondrial ROS produced via the glycerol 3-phosphate shuttle. Blood. PMID 34411229 DOI: 10.1182/blood.2021011010   
2021 Dong H, Liu M, Wang L, Liu Y, Lu X, Stagos D, Lin X, Liu M. Bromophenol Bis (2,3,6-Tribromo-4,5-dihydroxybenzyl) Ether Protects HaCaT Skin Cells from Oxidative Damage via Nrf2-Mediated Pathways. Antioxidants (Basel, Switzerland). 10. PMID 34573068 DOI: 10.3390/antiox10091436   
2021 Reynolds WJ, Bowman A, Hanson PS, Critchley A, Griffiths B, Chavan B, Birch-Machin MA. Adaptive responses to air pollution in human dermal fibroblasts and their potential roles in aging. Faseb Bioadvances. 3: 855-865. PMID 34632319 DOI: 10.1096/fba.2021-00056   
2021 Zeng D, Wang Y, Chen Y, Li D, Li G, Xiao H, Hou J, Wang Z, Hu L, Wang L, Li J. Angelica Polysaccharide Antagonizes 5-FU-Induced Oxidative Stress Injury to Reduce Apoptosis in the Liver Through Nrf2 Pathway. Frontiers in Oncology. 11: 720620. PMID 34485154 DOI: 10.3389/fonc.2021.720620   
2021 de Sousa IF, Migliaccio V, Lepretti M, Paolella G, Di Gregorio I, Caputo I, Ribeiro EB, Lionetti L. Dose- and Time-Dependent Effects of Oleate on Mitochondrial Fusion/Fission Proteins and Cell Viability in HepG2 Cells: Comparison with Palmitate Effects. International Journal of Molecular Sciences. 22. PMID 34575980 DOI: 10.3390/ijms22189812   
2021 Alam SI, Kim MW, Shah FA, Saeed K, Ullah R, Kim MO. Alpha-Linolenic Acid Impedes Cadmium-Induced Oxidative Stress, Neuroinflammation, and Neurodegeneration in Mouse Brain. Cells. 10. PMID 34571925 DOI: 10.3390/cells10092274   
2021 Wang Z, Fu Z, Wang C, Xu J, Ma H, Jiang M, Xu T, Feng X, Zhang W. ZLN005 protects against ischemia-reperfusion-induced kidney injury by mitigating oxidative stress through the restoration of mitochondrial fatty acid oxidation. American Journal of Translational Research. 13: 10014-10037. PMID 34650679   
2021 Han HJ, Park SK, Kang JY, Kim JM, Yoo SK, Kim DO, Kim GH, Heo HJ. Mixture of Phlorotannin and Fucoidan from Prevents the Aβ-Induced Cognitive Decline with Mitochondrial and Cholinergic Activation. Marine Drugs. 19. PMID 34436273 DOI: 10.3390/md19080434   
2021 Ouyang Q, Li Y, Mei S, Zhang Q, Li X, Luo H, Zhu Y, Wu K. Protective effects of GLHP from Gracilaria lemaneiformis against UVB-induced photodamage in human immortalized keratinocytes cells and BALB/c mice. Experimental Gerontology. 111550. PMID 34517082 DOI: 10.1016/j.exger.2021.111550   
2021 Prestes AS, Dos Santos MM, Kamdem JP, Mancini G, Schüler LC, de Bem AF, Barbosa NV. Methylglyoxal disrupts the functionality of rat liver mitochondria. Chemico-Biological Interactions. 109677. PMID 34634269 DOI: 10.1016/j.cbi.2021.109677   
2021 Xie QE, Wang MY, Cao ZP, Du X, Ji DM, Liang D, Cao YX, Liu YJ. Melatonin protects againstexcessive autophagy-induced mitochondrial and ovarian reserve function deficiency though ERK signaling pathway in Chinese hamster ovary (CHO) cells. Mitochondrion. PMID 34571250 DOI: 10.1016/j.mito.2021.09.009   
2021 Liu C, Li B, Yan Q, Niu S, Zhao Y, Xiong C, Zhang T, Wei J. Protective Effects and Mechanisms of Recombinant Human Glutathione Peroxidase 4 on Isoproterenol-Induced Myocardial Ischemia Injury. Oxidative Medicine and Cellular Longevity. 2021: 6632813. PMID 34539971 DOI: 10.1155/2021/6632813   
2021 Wang Y, He W, Wei W, Mei X, Yang M, Wang Y. Exenatide Attenuates Obesity-Induced Mitochondrial Dysfunction by Activating SIRT1 in Renal Tubular Cells. Frontiers in Endocrinology. 12: 622737. PMID 34434166 DOI: 10.3389/fendo.2021.622737   
2021 Yang X, Li Z, Zhang Y, Bu K, Tian J, Cui J, Qin J, Zhao R, Liu S, Tan G, Liu X. Human urinary kininogenase reduces the endothelial injury by inhibiting Pyk2/MCU pathway. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 143: 112165. PMID 34543986 DOI: 10.1016/j.biopha.2021.112165   
2021 King WT, Axelrod CL, Zunica ERM, Noland RC, Davuluri G, Fujioka H, Tandler B, Pergola K, Hermann GE, Rogers RC, López-Domènech S, Dantas WS, Stadler K, Hoppel CL, Kirwan JP. Dynamin-related protein 1 regulates substrate oxidation in skeletal muscle by stabilizing cellular and mitochondrial calcium dynamics. The Journal of Biological Chemistry. 101196. PMID 34529976 DOI: 10.1016/j.jbc.2021.101196   
2021 Zimmerman MA, Hall M, Qi Q, Mehta SL, Chen G, Li PA. Ubisol Coenzyme Q10 promotes mitochondrial biogenesis in HT22 cells challenged by glutamate. Experimental and Therapeutic Medicine. 22: 1295. PMID 34630650 DOI: 10.3892/etm.2021.10730   
2021 Turovsky EA, Varlamova EG, Plotnikov EY. Mechanisms Underlying the Protective Effect of the Peroxiredoxin-6 Are Mediated via the Protection of Astrocytes during Ischemia/Reoxygenation. International Journal of Molecular Sciences. 22. PMID 34445509 DOI: 10.3390/ijms22168805   
2021 Traore K, More P, Adla A, Dogbey G, Papadopoulos V, Zirkin B. MEHP induces alteration of mitochondrial function and inhibition of steroid biosynthesis in MA-10 mouse tumor Leydig cells. Toxicology. 463: 152985. PMID 34627990 DOI: 10.1016/j.tox.2021.152985   
2021 Cong P, Wang T, Tong C, Liu Y, Shi L, Mao S, Shi X, Jin H, Liu Y, Hou M. Resveratrol ameliorates thoracic blast exposure-induced inflammation, endoplasmic reticulum stress and apoptosis in the brain through the Nrf2/Keap1 and NF-κB signaling pathway. Injury. PMID 34454721 DOI: 10.1016/j.injury.2021.08.019