Beverly L. Davidson, PhD, University of Michigan - Publications

1999-2014 Internal Medicine University of Iowa, Iowa City, IA 
 2014- University of Pennsylvania, Philadelphia, PA, United States 
inherited genetic diseases

281 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ranum PT, Tecedor L, Keiser MS, Chen YH, Leib DE, Liu X, Davidson BL. Cochlear transduction via cerebrospinal fluid delivery of AAV in non-human primates. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 36610400 DOI: 10.1016/j.ymthe.2022.12.018  0.49
2022 Fang L, Monteys AM, Dürr A, Keiser M, Cheng C, Harapanahalli A, Gonzalez-Alegre P, Davidson BL, Wang K. Haplotyping SNPs for allele-specific gene editing of the expanded huntingtin allele using long-read sequencing. Hgg Advances. 4: 100146. PMID 36262216 DOI: 10.1016/j.xhgg.2022.100146  0.793
2022 Carrell EM, Keiser MS, Robbins AB, Davidson BL. Combined overexpression of ATXN1L and mutant ATXN1 knockdown by AAV rescue motor phenotypes and gene signatures in SCA1 mice. Molecular Therapy. Methods & Clinical Development. 25: 333-343. PMID 35573049 DOI: 10.1016/j.omtm.2022.04.004  0.354
2022 Keller CG, Shin Y, Monteys AM, Renaud N, Beibel M, Teider N, Peters T, Faller T, St-Cyr S, Knehr J, Roma G, Reyes A, Hild M, Lukashev D, Theil D, ... ... Davidson BL, et al. An orally available, brain penetrant, small molecule lowers huntingtin levels by enhancing pseudoexon inclusion. Nature Communications. 13: 1150. PMID 35241644 DOI: 10.1038/s41467-022-28653-6  0.322
2022 Leib D, Chen YH, Monteys AM, Davidson BL. Limited astrocyte-to-neuron conversion in the mouse brain using NeuroD1 overexpression. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 35123657 DOI: 10.1016/j.ymthe.2022.01.028  0.517
2021 Prezelski K, Keiser M, Stein JM, Lucas TH, Davidson B, Gonzalez-Alegre P, Vitale F. Design and Validation of a Multi-Point Injection Technology for MR-Guided Convection Enhanced Delivery in the Brain. Frontiers in Medical Technology. 3: 725844. PMID 35047955 DOI: 10.3389/fmedt.2021.725844  0.791
2021 Keiser MS, Ranum PT, Yrigollen CM, Carrell EM, Smith GR, Muehlmatt AL, Chen YH, Stein JM, Wolf RL, Radaelli E, Lucas TJ, Gonzalez-Alegre P, Davidson BL. Toxicity after AAV delivery of RNAi expression constructs into nonhuman primate brain. Nature Medicine. 27: 1982-1989. PMID 34663988 DOI: 10.1038/s41591-021-01522-3  0.327
2020 Pluciennik A, Liu Y, Molotsky E, Marsh GB, Ranxhi B, Arnold FJ, St-Cyr S, Davidson BL, Pourshafie N, Lieberman AP, Gu W, Todi SV, Merry DE. Deubiquitinase USP7 contributes to the pathogenicity of spinal and bulbar muscular atrophy. The Journal of Clinical Investigation. PMID 33170804 DOI: 10.1172/JCI134565  0.57
2020 Zhang Y, Yang HT, Kadash-Edmondson K, Pan Y, Pan Z, Davidson BL, Xing Y. Regional Variation of Splicing QTLs in Human Brain. American Journal of Human Genetics. PMID 32589925 DOI: 10.1016/J.Ajhg.2020.06.002  0.362
2020 Ahrens-Nicklas RC, Hall AF, Tecedor L, Stein CS, Lysenko E, Marsh ED, Davidson BL. Efficacy of cell-type specific rescue in a new mouse model of CLN3 disease Molecular Genetics and Metabolism. 129: S19. DOI: 10.1016/J.Ymgme.2019.11.019  0.33
2019 Davidson BL, Arruda VR. Gene therapy matures to medicines. Human Molecular Genetics. PMID 31595292 DOI: 10.1093/Hmg/Ddz182  0.305
2019 Ahrens-Nicklas RC, Tecedor L, Hall A, Lysenko E, Cohen AS, Davidson BL, Marsh ED. Neuronal network dysfunction precedes storage and neurodegeneration in a lysosomal storage disorder. Jci Insight. PMID 31573978 DOI: 10.1172/Jci.Insight.131961  0.359
2019 Davidson BL. Doubling down on siRNAs in the brain. Nature Biotechnology. 37: 865-866. PMID 31375811 DOI: 10.1038/S41587-019-0204-1  0.357
2019 Lang JF, Toulmin SA, Brida KL, Eisenlohr LC, Davidson BL. Standard screening methods underreport AAV-mediated transduction and gene editing. Nature Communications. 10: 3415. PMID 31363095 DOI: 10.1038/S41467-019-11321-7  0.391
2019 Yrigollen CM, Davidson BL. CRISPR to the Rescue: Advances in Gene Editing for the Gene. Brain Sciences. 9. PMID 30669625 DOI: 10.3390/Brainsci9010017  0.321
2018 Maguire JA, Gagne AL, Gonzalez-Alegre P, Davidson BL, Shakkottai V, Gadue P, French DL. Generation of Spinocerebellar Ataxia Type 2 induced pluripotent stem cell lines, CHOPi002-A and CHOPi003-A, from patients with abnormal CAG repeats in the coding region of the ATXN2 gene. Stem Cell Research. 34: 101361. PMID 30611021 DOI: 10.1016/J.Scr.2018.101361  0.326
2018 Amado DA, Rieders JM, Diatta F, Hernandez-Con P, Singer A, Mak JT, Zhang J, Lancaster E, Davidson BL, Chen-Plotkin AS. AAV-Mediated Progranulin Delivery to a Mouse Model of Progranulin Deficiency Causes T Cell-Mediated Toxicity. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 30559071 DOI: 10.1016/J.Ymthe.2018.11.013  0.412
2018 Chen YH, Keiser MS, Davidson BL. Adeno-Associated Virus Production, Purification, and Titering. Current Protocols in Mouse Biology. e56. PMID 30489697 DOI: 10.1002/Cpmo.56  0.346
2018 Chen YH, Keiser MS, Davidson BL. Viral Vectors for Gene Transfer. Current Protocols in Mouse Biology. e58. PMID 30485696 DOI: 10.1002/Cpmo.58  0.329
2018 Keiser MS, Chen YH, Davidson BL. Techniques for Intracranial Stereotaxic Injections of Adeno-Associated Viral Vectors in Adult Mice. Current Protocols in Mouse Biology. e57. PMID 30395418 DOI: 10.1002/Cpmo.57  0.376
2018 Cheng C, Spengler RM, Keiser MS, Monteys AM, Rieders JM, Ramachandran S, Davidson BL. The long noncoding RNA NEAT1 is elevated in polyglutamine repeat expansion diseases and protects from disease-gene dependent toxicities. Human Molecular Genetics. PMID 30239724 DOI: 10.1093/Hmg/Ddy331  0.79
2018 Child DD, Lee JH, Pascua CJ, Chen YH, Mas Monteys A, Davidson BL. Cardiac mTORC1 Dysregulation Impacts Stress Adaptation and Survival in Huntington's Disease. Cell Reports. 23: 1020-1033. PMID 29694882 DOI: 10.1016/J.Celrep.2018.03.117  0.3
2018 Schultz ML, Tecedor L, Lysenko E, Ramachandran S, Stein CS, Davidson BL. Modulating membrane fluidity corrects Batten disease phenotypes in vitro and in vivo. Neurobiology of Disease. PMID 29660499 DOI: 10.1016/J.Nbd.2018.04.010  0.751
2018 Chen Y, Zheng S, Tecedor L, Davidson BL. Overcoming Limitations Inherent in Sulfamidase to Improve Mucopolysaccharidosis IIIA Gene Therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 29503202 DOI: 10.1016/J.Ymthe.2018.01.010  0.407
2018 Victor MB, Richner M, Olsen HE, Lee SW, Monteys AM, Ma C, Huh CJ, Zhang B, Davidson BL, Yang XW, Yoo AS. Striatal neurons directly converted from Huntington's disease patient fibroblasts recapitulate age-associated disease phenotypes. Nature Neuroscience. PMID 29403030 DOI: 10.1038/S41593-018-0075-7  0.342
2017 Carmona V, Cunha-Santos J, Onofre I, Simões AT, Vijayakumar U, Davidson BL, Pereira de Almeida L. Unravelling Endogenous MicroRNA System Dysfunction as a New Pathophysiological Mechanism in Machado-Joseph Disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28236575 DOI: 10.1016/J.Ymthe.2017.01.021  0.396
2017 Kim YC, Miller A, Lins LC, Han SW, Keiser MS, Boudreau RL, Davidson BL, Narayanan NS. RNA Interference of Human α-Synuclein in Mouse. Frontiers in Neurology. 8: 13. PMID 28197125 DOI: 10.3389/Fneur.2017.00013  0.688
2017 Monteys AM, Ebanks SA, Keiser MS, Davidson BL. CRISPR/Cas9 Editing of the Mutant Huntingtin Allele In Vitro and In Vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 25: 12-23. PMID 28129107 DOI: 10.1016/J.Ymthe.2016.11.010  0.412
2017 Ahrens-Nicklas RC, Tecedor L, Schultz ML, Lysenko E, Ramachandran S, Marsh ED, Davidson BL. Small molecule therapies for juvenile neuronal ceroid lipofuscinosis Molecular Genetics and Metabolism. 120: S18-S19. DOI: 10.1016/J.Ymgme.2016.11.015  0.697
2016 Ramachandran S, Coffin SL, Tang TY, Jobaliya CD, Spengler RM, Davidson BL. Cis-acting single nucleotide polymorphisms alter MicroRNA-mediated regulation of human brain-expressed transcripts. Human Molecular Genetics. 25: 4939-4950. PMID 28171541 DOI: 10.1093/Hmg/Ddw317  0.767
2016 Dissen GA, Adachi K, Lomniczi A, Chatkupt T, Davidson BL, Nakai H, Ojeda SR. Engineering a gene silencing viral construct that targets the cat hypothalamus to induce permanent sterility: An update. Reproduction in Domestic Animals = Zuchthygiene. PMID 27859771 DOI: 10.1111/Rda.12834  0.43
2016 Keiser MS, Monteys AM, Corbau R, Gonzalez-Alegre P, Davidson BL. RNAi prevents and reverses phenotypes induced by mutant human ataxin-1. Annals of Neurology. PMID 27686464 DOI: 10.1002/Ana.24789  0.395
2016 Ramachandran S, Coffin SL, Tang TY, Jobaliya CD, Spengler RM, Davidson BL. Cis-Acting Single Nucleotide Polymorphisms Alter MicroRNA-Mediated Regulation of Human Brain-Expressed Transcripts. Human Molecular Genetics. PMID 27638890 DOI: 10.1093/hmg/ddw317  0.753
2016 Spengler RM, Zhang X, Cheng C, McLendon JM, Skeie JM, Johnson FL, Davidson BL, Boudreau RL. Elucidation of transcriptome-wide microRNA binding sites in human cardiac tissues by Ago2 HITS-CLIP. Nucleic Acids Research. PMID 27418678 DOI: 10.1093/Nar/Gkw640  0.785
2016 Lin L, Park JW, Ramachandran S, Zhang Y, Tseng YT, Shen S, Waldvogel HJ, Curtis MA, Faull RL, Troncoso JC, Ross CA, Davidson BL, Xing Y. Transcriptome sequencing reveals aberrant alternative splicing in Huntington's disease. Human Molecular Genetics. PMID 27378699 DOI: 10.1093/Hmg/Ddw187  0.421
2016 Ochaba J, Monteys AM, O'Rourke JG, Reidling JC, Steffan JS, Davidson BL, Thompson LM. PIAS1 Regulates Mutant Huntingtin Accumulation and Huntington's Disease-Associated Phenotypes In Vivo. Neuron. PMID 27146268 DOI: 10.1016/J.Neuron.2016.03.016  0.382
2016 Child D, Lee J, Davidson BL. B33 Decreased heart mass and dysregulated cardiac mTORC1 activity are associated with huntington’s disease Journal of Neurology, Neurosurgery & Psychiatry. 87: A20.3-A21. DOI: 10.1136/Jnnp-2016-314597.64  0.303
2016 Monteys AM, Ebanks SA, Keiser MS, Davidson BL. L1 CRISPR/Cas9 specific editing of the mutant huntingtin allele Journal of Neurology, Neurosurgery & Psychiatry. 87: A90.2-A90. DOI: 10.1136/Jnnp-2016-314597.256  0.409
2015 Katz ML, Tecedor L, Chen Y, Williamson BG, Lysenko E, Wininger FA, Young WM, Johnson GC, Whiting RE, Coates JR, Davidson BL. AAV gene transfer delays disease onset in a TPP1-deficient canine model of the late infantile form of Batten disease. Science Translational Medicine. 7: 313ra180. PMID 26560358 DOI: 10.1126/Scitranslmed.Aac6191  0.411
2015 Keiser MS, Kordower JH, Gonzalez-Alegre P, Davidson BL. Broad distribution of ataxin 1 silencing in rhesus cerebella for spinocerebellar ataxia type 1 therapy. Brain : a Journal of Neurology. PMID 26490326 DOI: 10.1093/Brain/Awv292  0.581
2015 Madhavan L, Daley BF, Davidson BL, Boudreau RL, Lipton JW, Cole-Strauss A, Steece-Collier K, Collier TJ. Sonic Hedgehog Controls the Phenotypic Fate and Therapeutic Efficacy of Grafted Neural Precursor Cells in a Model of Nigrostriatal Neurodegeneration. Plos One. 10: e0137136. PMID 26340267 DOI: 10.1371/Journal.Pone.0137136  0.664
2015 Monteys AM, Wilson MJ, Boudreau RL, Spengler RM, Davidson BL. Artificial miRNAs Targeting Mutant Huntingtin Show Preferential Silencing In Vitro and In Vivo. Molecular Therapy. Nucleic Acids. 4: e234. PMID 25849618 DOI: 10.1038/Mtna.2015.7  0.818
2015 Lee JH, Tecedor L, Chen YH, Monteys AM, Sowada MJ, Thompson LM, Davidson BL. Reinstating aberrant mTORC1 activity in Huntington's disease mice improves disease phenotypes. Neuron. 85: 303-15. PMID 25556834 DOI: 10.1016/J.Neuron.2014.12.019  0.378
2014 Monteys AM, Spengler RM, Dufour BD, Wilson MS, Oakley CK, Sowada MJ, McBride JL, Davidson BL. Single nucleotide seed modification restores in vivo tolerability of a toxic artificial miRNA sequence in the mouse brain. Nucleic Acids Research. 42: 13315-27. PMID 25332397 DOI: 10.1093/Nar/Gku979  0.817
2014 Geoghegan JC, Keiser NW, Okulist A, Martins I, Wilson MS, Davidson BL. Chondroitin Sulfate is the Primary Receptor for a Peptide-Modified AAV That Targets Brain Vascular Endothelium In Vivo. Molecular Therapy. Nucleic Acids. 3: e202. PMID 25313621 DOI: 10.1038/Mtna.2014.50  0.347
2014 Lee JH, Sowada MJ, Boudreau RL, Aerts AM, Thedens DR, Nopoulos P, Davidson BL. Rhes suppression enhances disease phenotypes in Huntington's disease mice. Journal of Huntington's Disease. 3: 65-71. PMID 25062765 DOI: 10.3233/Jhd-140094  0.696
2014 Krishnamurthy S, Behlke MA, Apicella MA, McCray PB, Davidson BL. Platelet Activating Factor Receptor Activation Improves siRNA Uptake and RNAi Responses in Well-differentiated Airway Epithelia. Molecular Therapy. Nucleic Acids. 3: e175. PMID 25025465 DOI: 10.1038/Mtna.2014.26  0.318
2014 Puppo A, Cesi G, Marrocco E, Piccolo P, Jacca S, Shayakhmetov DM, Parks RJ, Davidson BL, Colloca S, Brunetti-Pierri N, Ng P, Donofrio G, Auricchio A. Retinal transduction profiles by high-capacity viral vectors. Gene Therapy. 21: 855-65. PMID 24989814 DOI: 10.1038/Gt.2014.57  0.348
2014 Ramachandran PS, Boudreau RL, Schaefer KA, La Spada AR, Davidson BL. Nonallele specific silencing of ataxin-7 improves disease phenotypes in a mouse model of SCA7. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1635-42. PMID 24930601 DOI: 10.1038/Mt.2014.108  0.811
2014 Schultz ML, Tecedor L, Stein CS, Stamnes MA, Davidson BL. CLN3 deficient cells display defects in the ARF1-Cdc42 pathway and actin-dependent events. Plos One. 9: e96647. PMID 24792215 DOI: 10.1371/Journal.Pone.0096647  0.731
2014 Ramachandran PS, Bhattarai S, Singh P, Boudreau RL, Thompson S, Laspada AR, Drack AV, Davidson BL. RNA interference-based therapy for spinocerebellar ataxia type 7 retinal degeneration. Plos One. 9: e95362. PMID 24759684 DOI: 10.1371/Journal.Pone.0095362  0.792
2014 Keiser MS, Boudreau RL, Davidson BL. Broad therapeutic benefit after RNAi expression vector delivery to deep cerebellar nuclei: implications for spinocerebellar ataxia type 1 therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 588-95. PMID 24419082 DOI: 10.1038/Mt.2013.279  0.722
2014 Boudreau RL, Jiang P, Gilmore BL, Spengler RM, Tirabassi R, Nelson JA, Ross CA, Xing Y, Davidson BL. Transcriptome-wide discovery of microRNA binding sites in human brain. Neuron. 81: 294-305. PMID 24389009 DOI: 10.1016/J.Neuron.2013.10.062  0.805
2014 McLoughlin HS, Wan J, Spengler RM, Xing Y, Davidson BL. Human-specific microRNA regulation of FOXO1: implications for microRNA recognition element evolution. Human Molecular Genetics. 23: 2593-603. PMID 24368418 DOI: 10.1093/Hmg/Ddt655  0.792
2014 Griffin MA, Restrepo MS, Abu-El-Haija M, Wallen T, Buchanan E, Rokhlina T, Chen YH, McCray PB, Davidson BL, Divekar A, Uc A. A novel gene delivery method transduces porcine pancreatic duct epithelial cells. Gene Therapy. 21: 123-30. PMID 24257348 DOI: 10.1038/Gt.2013.62  0.35
2014 Spengler RM, Oakley CK, Davidson BL. Functional microRNAs and target sites are created by lineage-specific transposition. Human Molecular Genetics. 23: 1783-93. PMID 24234653 DOI: 10.1093/Hmg/Ddt569  0.76
2014 Ochaba J, O'Rourke J, Monteys A, Lee J, Steffan J, Davidson B, Thompson L. A26 Basic Understanding: The Role Of Abnormal Htt Accumulation Journal of Neurology, Neurosurgery & Psychiatry. 85: A8-A8. DOI: 10.1136/Jnnp-2014-309032.26  0.4
2013 Rodríguez-Lebrón E, Costa MD, Luna-Cancalon K, Peron TM, Fischer S, Boudreau RL, Davidson BL, Paulson HL. Silencing Mutant ATXN3 Expression Resolves Molecular Phenotypes in SCA3 Transgenic Mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1909-1918. PMID 28157530 DOI: 10.1038/mt.2013.152  0.703
2013 do Carmo Costa M, Luna-Cancalon K, Fischer S, Ashraf NS, Ouyang M, Dharia RM, Martin-Fishman L, Yang Y, Shakkottai VG, Davidson BL, Rodríguez-Lebrón E, Paulson HL. Toward RNAi Therapy for the Polyglutamine Disease Machado-Joseph Disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1898-1908. PMID 28157529 DOI: 10.1038/mt.2013.144  0.375
2013 Hudry E, Dashkoff J, Roe AD, Takeda S, Koffie RM, Hashimoto T, Scheel M, Spires-Jones T, Arbel-Ornath M, Betensky R, Davidson BL, Hyman BT. Gene transfer of human Apoe isoforms results in differential modulation of amyloid deposition and neurotoxicity in mouse brain. Science Translational Medicine. 5: 212ra161. PMID 24259049 DOI: 10.1126/Scitranslmed.3007000  0.334
2013 Tecedor L, Stein CS, Schultz ML, Farwanah H, Sandhoff K, Davidson BL. CLN3 loss disturbs membrane microdomain properties and protein transport in brain endothelial cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 18065-79. PMID 24227717 DOI: 10.1523/Jneurosci.0498-13.2013  0.728
2013 O'Rourke JG, Gareau JR, Ochaba J, Song W, Raskó T, Reverter D, Lee J, Monteys AM, Pallos J, Mee L, Vashishtha M, Apostol BL, Nicholson TP, Illes K, Zhu YZ, ... ... Davidson B, et al. SUMO-2 and PIAS1 modulate insoluble mutant huntingtin protein accumulation. Cell Reports. 4: 362-75. PMID 23871671 DOI: 10.1016/J.Celrep.2013.06.034  0.327
2013 Rodríguez-Lebrón E, Costa Mdo C, Costa Md, Luna-Cancalon K, Peron TM, Fischer S, Boudreau RL, Davidson BL, Paulson HL. Silencing mutant ATXN3 expression resolves molecular phenotypes in SCA3 transgenic mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1909-18. PMID 23820820 DOI: 10.1038/Mt.2013.152  0.727
2013 Costa Mdo C, Luna-Cancalon K, Fischer S, Ashraf NS, Ouyang M, Dharia RM, Martin-Fishman L, Yang Y, Shakkottai VG, Davidson BL, Rodríguez-Lebrón E, Paulson HL. Toward RNAi therapy for the polyglutamine disease Machado-Joseph disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1898-908. PMID 23765441 DOI: 10.1038/Mt.2013.144  0.478
2013 Benraiss A, Toner MJ, Xu Q, Bruel-Jungerman E, Rogers EH, Wang F, Economides AN, Davidson BL, Kageyama R, Nedergaard M, Goldman SA. Sustained mobilization of endogenous neural progenitors delays disease progression in a transgenic model of Huntington's disease. Cell Stem Cell. 12: 787-99. PMID 23746982 DOI: 10.1016/J.Stem.2013.04.014  0.368
2013 Ramachandran S, Krishnamurthy S, Jacobi AM, Wohlford-Lenane C, Behlke MA, Davidson BL, McCray PB. Efficient delivery of RNA interference oligonucleotides to polarized airway epithelia in vitro. American Journal of Physiology. Lung Cellular and Molecular Physiology. 305: L23-32. PMID 23624792 DOI: 10.1152/Ajplung.00426.2012  0.37
2013 Ramachandran PS, Keiser MS, Davidson BL. Recent advances in RNA interference therapeutics for CNS diseases. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 10: 473-85. PMID 23589092 DOI: 10.1007/S13311-013-0183-8  0.768
2013 Keiser MS, Geoghegan JC, Boudreau RL, Lennox KA, Davidson BL. RNAi or overexpression: alternative therapies for Spinocerebellar Ataxia Type 1. Neurobiology of Disease. 56: 6-13. PMID 23583610 DOI: 10.1016/J.Nbd.2013.04.003  0.72
2013 Rodriguez-Lebron E, Liu G, Keiser M, Behlke MA, Davidson BL. Altered Purkinje cell miRNA expression and SCA1 pathogenesis. Neurobiology of Disease. 54: 456-63. PMID 23376683 DOI: 10.1016/J.Nbd.2013.01.019  0.788
2013 Cheng C, Chen YH, Lennox KA, Behlke MA, Davidson BL. In vivo SELEX for Identification of Brain-penetrating Aptamers. Molecular Therapy. Nucleic Acids. 2: e67. PMID 23299833 DOI: 10.1038/Mtna.2012.59  0.346
2013 Conforti P, Mas Monteys A, Zuccato C, Buckley NJ, Davidson B, Cattaneo E. In vivo delivery of DN:REST improves transcriptional changes of REST-regulated genes in HD mice. Gene Therapy. 20: 678-85. PMID 23151521 DOI: 10.1038/Gt.2012.84  0.434
2013 Boudreau RL, Spengler RM, Hylock RH, Kusenda BJ, Davis HA, Eichmann DA, Davidson BL. siSPOTR: a tool for designing highly specific and potent siRNAs for human and mouse. Nucleic Acids Research. 41: e9. PMID 22941647 DOI: 10.1093/Nar/Gks797  0.801
2013 Uc A, Griffin M, Abu-El-Haija M, Restrepo M, Wallen T, McCray P, Davidson B, Divekar A. A novel delivery method to transduce genes in the pancreas Pancreatology. 13: e80. DOI: 10.1016/J.Pan.2012.12.335  0.3
2012 Geoghegan JC, Gilmore BL, Davidson BL. Gene Silencing Mediated by siRNA-binding Fusion Proteins Is Attenuated by Double-stranded RNA-binding Domain Structure. Molecular Therapy. Nucleic Acids. 1: e53. PMID 23629028 DOI: 10.1038/Mtna.2012.43  0.361
2012 Krishnamurthy S, Behlke MA, Ramachandran S, Salem AK, McCray PB, Davidson BL. Manipulation of Cell Physiology Enables Gene Silencing in Well-differentiated Airway Epithelia. Molecular Therapy. Nucleic Acids. 1: e41. PMID 23344182 DOI: 10.1038/Mtna.2012.36  0.406
2012 Davidson BL. Taking a break from huntingtin. Molecular Therapy. Nucleic Acids. 1. PMID 23344175 DOI: 10.1038/Mtna.2012.33  0.438
2012 Dissen GA, Lomniczi A, Boudreau RL, Chen YH, Davidson BL, Ojeda SR. Applying gene silencing technology to contraception. Reproduction in Domestic Animals = Zuchthygiene. 47: 381-6. PMID 23279544 DOI: 10.1111/Rda.12016  0.694
2012 Davidson BL. Taking a break from huntingtin. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 1838. PMID 23023055 DOI: 10.1038/Mt.2012.191  0.332
2012 Davidson BL, Monteys AM. Singles engage the RNA interference pathway. Cell. 150: 873-5. PMID 22939614 DOI: 10.1016/J.Cell.2012.08.008  0.314
2012 McLoughlin HS, Fineberg SK, Ghosh LL, Tecedor L, Davidson BL. Dicer is required for proliferation, viability, migration and differentiation in corticoneurogenesis. Neuroscience. 223: 285-95. PMID 22898830 DOI: 10.1016/J.Neuroscience.2012.08.009  0.795
2012 Dissen GA, Lomniczi A, Boudreau RL, Chen YH, Davidson BL, Ojeda SR. Targeted gene silencing to induce permanent sterility. Reproduction in Domestic Animals = Zuchthygiene. 47: 228-32. PMID 22827375 DOI: 10.1111/J.1439-0531.2012.02080.X  0.695
2012 Fineberg SK, Datta P, Stein CS, Davidson BL. MiR-34a represses Numbl in murine neural progenitor cells and antagonizes neuronal differentiation. Plos One. 7: e38562. PMID 22701667 DOI: 10.1371/Journal.Pone.0038562  0.653
2012 Chen YH, Claflin K, Geoghegan JC, Davidson BL. Sialic acid deposition impairs the utility of AAV9, but not peptide-modified AAVs for brain gene therapy in a mouse model of lysosomal storage disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 1393-9. PMID 22588273 DOI: 10.1038/Mt.2012.100  0.392
2012 Boudreau RL, Davidson BL. Generation of hairpin-based RNAi vectors for biological and therapeutic application. Methods in Enzymology. 507: 275-96. PMID 22365779 DOI: 10.1016/B978-0-12-386509-0.00014-4  0.702
2012 Benraiss A, Bruel-Jungerman E, Lu G, Economides AN, Davidson B, Goldman SA. Sustained induction of neuronal addition to the adult rat neostriatum by AAV4-delivered noggin and BDNF. Gene Therapy. 19: 483-93. PMID 21918547 DOI: 10.1038/Gt.2011.114  0.331
2011 McBride JL, Pitzer MR, Boudreau RL, Dufour B, Hobbs T, Ojeda SR, Davidson BL. Preclinical safety of RNAi-mediated HTT suppression in the rhesus macaque as a potential therapy for Huntington's disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 2152-62. PMID 22031240 DOI: 10.1038/Mt.2011.219  0.812
2011 Boudreau RL, Spengler RM, Davidson BL. Rational design of therapeutic siRNAs: minimizing off-targeting potential to improve the safety of RNAi therapy for Huntington's disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 2169-77. PMID 21952166 DOI: 10.1038/Mt.2011.185  0.816
2011 Schultz ML, Tecedor L, Chang M, Davidson BL. Clarifying lysosomal storage diseases. Trends in Neurosciences. 34: 401-10. PMID 21723623 DOI: 10.1016/J.Tins.2011.05.006  0.718
2011 Davidson BL, McCray PB. Current prospects for RNA interference-based therapies. Nature Reviews. Genetics. 12: 329-40. PMID 21499294 DOI: 10.1038/Nrg2968  0.4
2011 Boudreau RL, Rodríguez-Lebrón E, Davidson BL. RNAi medicine for the brain: progresses and challenges. Human Molecular Genetics. 20: R21-7. PMID 21459775 DOI: 10.1093/Hmg/Ddr137  0.682
2011 Shen S, Lin L, Cai JJ, Jiang P, Kenkel EJ, Stroik MR, Sato S, Davidson BL, Xing Y. Widespread establishment and regulatory impact of Alu exons in human genes. Proceedings of the National Academy of Sciences of the United States of America. 108: 2837-42. PMID 21282640 DOI: 10.1073/Pnas.1012834108  0.38
2011 Spencer NY, Yan Z, Boudreau RL, Zhang Y, Luo M, Li Q, Tian X, Shah AM, Davisson RL, Davidson B, Banfi B, Engelhardt JF. Control of hepatic nuclear superoxide production by glucose 6-phosphate dehydrogenase and NADPH oxidase-4. The Journal of Biological Chemistry. 286: 8977-87. PMID 21212270 DOI: 10.1074/Jbc.M110.193821  0.614
2011 Ding SL, Tecedor L, Stein CS, Davidson BL. A knock-in reporter mouse model for Batten disease reveals predominant expression of Cln3 in visual, limbic and subcortical motor structures. Neurobiology of Disease. 41: 237-48. PMID 20875858 DOI: 10.1016/J.Nbd.2010.09.011  0.343
2010 Piedrahita D, Hernández I, López-Tobón A, Fedorov D, Obara B, Manjunath BS, Boudreau RL, Davidson B, Laferla F, Gallego-Gómez JC, Kosik KS, Cardona-Gómez GP. Silencing of CDK5 reduces neurofibrillary tangles in transgenic alzheimer's mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 13966-76. PMID 20962218 DOI: 10.1523/Jneurosci.3637-10.2010  0.668
2010 Lin L, Shen S, Jiang P, Sato S, Davidson BL, Xing Y. Evolution of alternative splicing in primate brain transcriptomes. Human Molecular Genetics. 19: 2958-73. PMID 20460271 DOI: 10.1093/Hmg/Ddq201  0.372
2010 Johnson CD, Davidson BL. Huntington's disease: progress toward effective disease-modifying treatments and a cure. Human Molecular Genetics. 19: R98-R102. PMID 20421366 DOI: 10.1093/Hmg/Ddq148  0.375
2010 Boudreau RL, Davidson BL. RNAi therapeutics for CNS disorders. Brain Research. 1338: 112-21. PMID 20307511 DOI: 10.1016/J.Brainres.2010.03.038  0.709
2010 Stein CS, Yancey PH, Martins I, Sigmund RD, Stokes JB, Davidson BL. Osmoregulation of ceroid neuronal lipofuscinosis type 3 in the renal medulla. American Journal of Physiology. Cell Physiology. 298: C1388-400. PMID 20219947 DOI: 10.1152/Ajpcell.00272.2009  0.35
2010 Ebert SM, Monteys AM, Fox DK, Bongers KS, Shields BE, Malmberg SE, Davidson BL, Suneja M, Adams CM. The transcription factor ATF4 promotes skeletal myofiber atrophy during fasting. Molecular Endocrinology (Baltimore, Md.). 24: 790-9. PMID 20197309 DOI: 10.1210/Jcem.95.3.9993  0.315
2010 Monteys AM, Spengler RM, Wan J, Tecedor L, Lennox KA, Xing Y, Davidson BL. Structure and activity of putative intronic miRNA promoters. Rna (New York, N.Y.). 16: 495-505. PMID 20075166 DOI: 10.1261/Rna.1731910  0.755
2010 Tecedor L, Stein C, Davidson B. 133. Lack of CLN3 results in altered physiology of mouse brain endothelial cells Molecular Genetics and Metabolism. 99: S35. DOI: 10.1016/J.Ymgme.2009.10.150  0.309
2010 Davidson B, Chen Y, Chang M. 35. Disease brain endothelia provide unique molecular signatures for CNS-directed enzyme therapy Molecular Genetics and Metabolism. 99: S15. DOI: 10.1016/J.Ymgme.2009.10.052  0.317
2009 Fineberg SK, Kosik KS, Davidson BL. MicroRNAs potentiate neural development. Neuron. 64: 303-9. PMID 19914179 DOI: 10.1016/J.Neuron.2009.10.020  0.68
2009 Borchert GM, Gilmore BL, Spengler RM, Xing Y, Lanier W, Bhattacharya D, Davidson BL. Adenosine deamination in human transcripts generates novel microRNA binding sites. Human Molecular Genetics. 18: 4801-7. PMID 19776031 DOI: 10.1093/Hmg/Ddp443  0.801
2009 Chen YH, Chang M, Davidson BL. Molecular signatures of disease brain endothelia provide new sites for CNS-directed enzyme therapy. Nature Medicine. 15: 1215-8. PMID 19749771 DOI: 10.1038/Nm.2025  0.39
2009 Quinn K, Brindley MA, Weller ML, Kaludov N, Kondratowicz A, Hunt CL, Sinn PL, McCray PB, Stein CS, Davidson BL, Flick R, Mandell R, Staplin W, Maury W, Chiorini JA. Rho GTPases modulate entry of Ebola virus and vesicular stomatitis virus pseudotyped vectors. Journal of Virology. 83: 10176-86. PMID 19625394 DOI: 10.1128/Jvi.00422-09  0.324
2009 Rodríguez-Lebrón E, Gouvion CM, Moore SA, Davidson BL, Paulson HL. Allele-specific RNAi mitigates phenotypic progression in a transgenic model of Alzheimer's disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 1563-73. PMID 19532137 DOI: 10.1038/Mt.2009.123  0.368
2009 Lin L, Jiang P, Shen S, Sato S, Davidson BL, Xing Y. Large-scale analysis of exonized mammalian-wide interspersed repeats in primate genomes. Human Molecular Genetics. 18: 2204-14. PMID 19324900 DOI: 10.1093/Hmg/Ddp152  0.309
2009 Hadaczek P, Forsayeth J, Mirek H, Munson K, Bringas J, Pivirotto P, McBride JL, Davidson BL, Bankiewicz KS. Transduction of nonhuman primate brain with adeno-associated virus serotype 1: vector trafficking and immune response. Human Gene Therapy. 20: 225-37. PMID 19292604 DOI: 10.1089/Hum.2008.151  0.606
2009 Boudreau RL, McBride JL, Martins I, Shen S, Xing Y, Carter BJ, Davidson BL. Nonallele-specific silencing of mutant and wild-type huntingtin demonstrates therapeutic efficacy in Huntington's disease mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 1053-63. PMID 19240687 DOI: 10.1038/Mt.2009.17  0.768
2009 Boudreau RL, Martins I, Davidson BL. Artificial microRNAs as siRNA shuttles: improved safety as compared to shRNAs in vitro and in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 169-75. PMID 19002161 DOI: 10.1038/Mt.2008.231  0.706
2008 Packer AN, Xing Y, Harper SQ, Jones L, Davidson BL. The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 14341-6. PMID 19118166 DOI: 10.1523/Jneurosci.2390-08.2008  0.624
2008 Coryell MW, Wunsch AM, Haenfler JM, Allen JE, McBride JL, Davidson BL, Wemmie JA. Restoring Acid-sensing ion channel-1a in the amygdala of knock-out mice rescues fear memory but not unconditioned fear responses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 13738-41. PMID 19091964 DOI: 10.1523/Jneurosci.3907-08.2008  0.535
2008 Boudreau RL, Monteys AM, Davidson BL. Minimizing variables among hairpin-based RNAi vectors reveals the potency of shRNAs. Rna (New York, N.Y.). 14: 1834-44. PMID 18697922 DOI: 10.1261/Rna.1062908  0.711
2008 McBride JL, Boudreau RL, Harper SQ, Staber PD, Monteys AM, Martins I, Gilmore BL, Burstein H, Peluso RW, Polisky B, Carter BJ, Davidson BL. Artificial miRNAs mitigate shRNA-mediated toxicity in the brain: implications for the therapeutic development of RNAi. Proceedings of the National Academy of Sciences of the United States of America. 105: 5868-73. PMID 18398004 DOI: 10.1073/Pnas.0801775105  0.833
2008 Chang M, Cooper JD, Sleat DE, Cheng SH, Dodge JC, Passini MA, Lobel P, Davidson BL. Intraventricular enzyme replacement improves disease phenotypes in a mouse model of late infantile neuronal ceroid lipofuscinosis. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 649-56. PMID 18362923 DOI: 10.1038/Mt.2008.9  0.395
2008 Fineberg SK, Ghosh LL, He B, Harper SQ, Davidson BL. miR-34a modulates neural progenitor cell differentiation Developmental Biology. 319: 535. DOI: 10.1016/J.Ydbio.2008.05.251  0.73
2007 Eliason SL, Stein CS, Mao Q, Tecedor L, Ding SL, Gaines DM, Davidson BL. A knock-in reporter model of Batten disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 9826-34. PMID 17855597 DOI: 10.1523/Jneurosci.1710-07.2007  0.398
2007 Cabrera-Salazar MA, Roskelley EM, Bu J, Hodges BL, Yew N, Dodge JC, Shihabuddin LS, Sohar I, Sleat DE, Scheule RK, Davidson BL, Cheng SH, Lobel P, Passini MA. Timing of therapeutic intervention determines functional and survival outcomes in a mouse model of late infantile batten disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 1782-8. PMID 17637720 DOI: 10.1038/Sj.Mt.6300249  0.37
2007 Kumar P, Wu H, McBride JL, Jung KE, Kim MH, Davidson BL, Lee SK, Shankar P, Manjunath N. Transvascular delivery of small interfering RNA to the central nervous system. Nature. 448: 39-43. PMID 17572664 DOI: 10.1038/Nature05901  0.593
2007 Davidson BL, Boudreau RL. RNA interference: a tool for querying nervous system function and an emerging therapy. Neuron. 53: 781-8. PMID 17359914 DOI: 10.1016/J.Neuron.2007.02.020  0.707
2007 Liu G, Chen YH, He X, Martins I, Heth JA, Chiorini JA, Davidson BL. Adeno-associated virus type 5 reduces learning deficits and restores glutamate receptor subunit levels in MPS VII mice CNS. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 242-7. PMID 17235300 DOI: 10.1038/Sj.Mt.6300016  0.798
2006 Allaire PD, Ritter B, Thomas S, Burman JL, Denisov AY, Legendre-Guillemin V, Harper SQ, Davidson BL, Gehring K, McPherson PS. Connecdenn, a novel DENN domain-containing protein of neuronal clathrin-coated vesicles functioning in synaptic vesicle endocytosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 13202-12. PMID 17182770 DOI: 10.1523/Jneurosci.4608-06.2006  0.596
2006 Borchert GM, Lanier W, Davidson BL. RNA polymerase III transcribes human microRNAs. Nature Structural & Molecular Biology. 13: 1097-101. PMID 17099701 DOI: 10.1038/Nsmb1167  0.697
2006 Boudreau RL, Davidson BL. RNAi therapy for neurodegenerative diseases. Current Topics in Developmental Biology. 75: 73-92. PMID 16984810 DOI: 10.1016/S0070-2153(06)75003-7  0.708
2006 Harper SQ, Staber PD, Beck CR, Fineberg SK, Stein C, Ochoa D, Davidson BL. Optimization of feline immunodeficiency virus vectors for RNA interference. Journal of Virology. 80: 9371-80. PMID 16973543 DOI: 10.1128/Jvi.00958-06  0.791
2006 Kang Y, Moressi CJ, Scheetz TE, Xie L, Tran DT, Casavant TL, Ak P, Benham CJ, Davidson BL, McCray PB. Integration site choice of a feline immunodeficiency virus vector. Journal of Virology. 80: 8820-3. PMID 16912328 DOI: 10.1128/Jvi.00719-06  0.314
2006 Alisky JM, Xia H, Davidson BL. A TAT-modified fusion protein efficiently penetrates mouse hypoglossal nuclei from transduced ependyma. Neuroscience Letters. 401: 40-3. PMID 16650576 DOI: 10.1016/J.Neulet.2006.03.076  0.362
2006 Sands MS, Davidson BL. Gene therapy for lysosomal storage diseases. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 839-49. PMID 16545619 DOI: 10.1016/J.Ymthe.2006.01.006  0.351
2006 Passini MA, Dodge JC, Bu J, Yang W, Zhao Q, Sondhi D, Hackett NR, Kaminsky SM, Mao Q, Shihabuddin LS, Cheng SH, Sleat DE, Stewart GR, Davidson BL, Lobel P, et al. Intracranial delivery of CLN2 reduces brain pathology in a mouse model of classical late infantile neuronal ceroid lipofuscinosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1334-42. PMID 16452657 DOI: 10.1523/Jneurosci.2676-05.2006  0.414
2006 Denovan-Wright EM, Davidson BL. RNAi: a potential therapy for the dominantly inherited nucleotide repeat diseases. Gene Therapy. 13: 525-31. PMID 16237462 DOI: 10.1038/Sj.Gt.3302664  0.41
2006 Mas-Monteys A, Harper SQ, Gilmore BL, Staber PD, Schaffer C, Polisky B, Vargeese C, Davidson BL. 711. Allele-Specific Silencing of Mutant Huntingtin for Huntington's Disease Therapy Molecular Therapy. 13: S274-S275. DOI: 10.1016/J.Ymthe.2006.08.790  0.68
2006 McBride JL, Harper SQ, Staber PD, Martins IH, Burstein H, Peluso RW, Polisky B, Carter BJ, Davidson BL. 414. Non-Allele Specific RNA Interference in the CAG140 Knock-In Mouse Model of Huntington's Disease Molecular Therapy. 13: S159. DOI: 10.1016/J.Ymthe.2006.08.478  0.754
2006 Harper SQ, Staber PD, Rowley C, Fineberg S, Ochoa D, Stein C, Davidson BL. 371. Optimization of Feline Immunodeficiency Viral Vectors for RNA Interference Molecular Therapy. 13: S141. DOI: 10.1016/J.Ymthe.2006.08.430  0.787
2006 Chang M, Sleat D, Cheng S, Passini M, Lobel P, Davidson BL. 218. Gene Therapy and Enzyme Replacement in a Mouse Model of Late Infantile Neuronal Ceroid Lipofuscinosis Molecular Therapy. 13: S84. DOI: 10.1016/J.Ymthe.2006.08.243  0.353
2006 Boudreau RL, Davidson BL. 90. miRNA Shuttles Improve Therapeutic RNAi Molecular Therapy. 13: S37. DOI: 10.1016/J.Ymthe.2006.08.108  0.721
2006 Staber PD, Vargeese C, Martins IH, Polisky B, Mas-Monteys A, Harper SQ, Davidson BL. 88. Synthetic siRNAs for Huntington's Disease Therapy Molecular Therapy. 13. DOI: 10.1016/J.Ymthe.2006.08.106  0.662
2006 Vibhakar R, Davidson BL, Madan A. 942. Adenoviral Mediated Re-Expression of Wnt Antagonist Dkk-1 Induces Apoptosis and Suppresses Tumor Growth in Medulloblastoma Molecular Therapy. 13: S363. DOI: 10.1016/J.Ymthe.2006.08.1033  0.33
2005 Gonzalez-Alegre P, Bode N, Davidson BL, Paulson HL. Silencing primary dystonia: lentiviral-mediated RNA interference therapy for DYT1 dystonia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 10502-9. PMID 16280588 DOI: 10.1523/Jneurosci.3016-05.2005  0.447
2005 Liu G, Martins I, Wemmie JA, Chiorini JA, Davidson BL. Functional correction of CNS phenotypes in a lysosomal storage disease model using adeno-associated virus type 4 vectors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9321-7. PMID 16221840 DOI: 10.1523/Jneurosci.2936-05.2005  0.809
2005 Miller VM, Nelson RF, Gouvion CM, Williams A, Rodriguez-Lebron E, Harper SQ, Davidson BL, Rebagliati MR, Paulson HL. CHIP suppresses polyglutamine aggregation and toxicity in vitro and in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9152-61. PMID 16207874 DOI: 10.1523/Jneurosci.3001-05.2005  0.726
2005 Law LK, Davidson BL. What does it take to bind CAR? Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 599-609. PMID 16109509 DOI: 10.1016/J.Ymthe.2005.05.017  0.599
2005 Orii KO, Grubb JH, Vogler C, Levy B, Tan Y, Markova K, Davidson BL, Mao Q, Orii T, Kondo N, Sly WS. Defining the pathway for Tat-mediated delivery of beta-glucuronidase in cultured cells and MPS VII mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 345-52. PMID 16043103 DOI: 10.1016/J.Ymthe.2005.02.031  0.316
2005 Harper SQ, Davidson BL. Plasmid-based RNA interference: construction of small-hairpin RNA expression vectors. Methods in Molecular Biology (Clifton, N.J.). 309: 219-35. PMID 15990403 DOI: 10.1385/1-59259-935-4:219  0.634
2005 Liu G, Martins IH, Chiorini JA, Davidson BL. Adeno-associated virus type 4 (AAV4) targets ependyma and astrocytes in the subventricular zone and RMS. Gene Therapy. 12: 1503-8. PMID 15944733 DOI: 10.1038/Sj.Gt.3302554  0.796
2005 Kang Y, Xie L, Tran DT, Stein CS, Hickey M, Davidson BL, McCray PB. Persistent expression of factor VIII in vivo following nonprimate lentiviral gene transfer. Blood. 106: 1552-8. PMID 15886327 DOI: 10.1182/Blood-2004-11-4358  0.385
2005 Harper SQ, Staber PD, He X, Eliason SL, Martins IH, Mao Q, Yang L, Kotin RM, Paulson HL, Davidson BL. RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model. Proceedings of the National Academy of Sciences of the United States of America. 102: 5820-5. PMID 15811941 DOI: 10.1073/Pnas.0501507102  0.702
2005 Stein CS, Martins I, Davidson BL. The lymphocytic choriomeningitis virus envelope glycoprotein targets lentiviral gene transfer vector to neural progenitors in the murine brain. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 382-9. PMID 15727934 DOI: 10.1016/J.Ymthe.2004.11.008  0.386
2005 Davidson BL, Harper SQ. Viral delivery of recombinant short hairpin RNAs. Methods in Enzymology. 392: 145-73. PMID 15644180 DOI: 10.1016/S0076-6879(04)92009-5  0.669
2005 Fischer AJ, Wohlford-Lenane CL, Sinn PL, Jia HP, Varga SM, Davidson BL, McCray PB. 816. RNAi Applications for Respiratory Epithelia: Delivery and Efficacy Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.359  0.42
2005 Glover CP, Bienemann AS, Davidson BL, Uney JB. 656. Development of Viral Vectors To Mediate Neuron-Specific Gene Silencing Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.196  0.475
2005 Kang Y, Xie L, Tran DT, Stein CS, Hickey M, Davidson BL, McCray PB. 601. Persistent Expression of Factor VIII In Vivo Following FIV Lentiviral Gene Transfer Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.141  0.383
2005 Passini MA, Sondhi D, Dodge JC, Bu J, Yang W, Hackett NR, Kaminsky SM, El-Banna M, Mao Q, Davidson BL, Sleat DE, Lobel P, Crystal RG, Stewart GR. 427. AAV2- and AAV5-Mediated CNS Delivery of Human CLN2 Reduces Lysosomal Storage in a Mouse Model of Late Infantile Neuronal Ceroid Lipofuscinosis Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.429  0.372
2005 Chen YH, Davidson BL. 420. Tropism-Modified Adeno-Associated Virus Vector Mediates Targeting of Brain Vascular Endothelium In Vivo Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.423  0.379
2005 Harper SQ, Staber PD, He X, Martins IH, Mao Q, Paulson HL, Kotin RM, Davidson BL. 52. AAV-Delivered RNAi Improves Cellular and Motor Phenotypes in a Mouse Model for Huntington's Disease Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.080  0.703
2004 Sleat DE, Wiseman JA, El-Banna M, Kim KH, Mao Q, Price S, Macauley SL, Sidman RL, Shen MM, Zhao Q, Passini MA, Davidson BL, Stewart GR, Lobel P. A mouse model of classical late-infantile neuronal ceroid lipofuscinosis based on targeted disruption of the CLN2 gene results in a loss of tripeptidyl-peptidase I activity and progressive neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 9117-26. PMID 15483130 DOI: 10.1523/Jneurosci.2729-04.2004  0.401
2004 Xia H, Mao Q, Eliason SL, Harper SQ, Martins IH, Orr HT, Paulson HL, Yang L, Kotin RM, Davidson BL. RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia. Nature Medicine. 10: 816-20. PMID 15235598 DOI: 10.1038/Nm1076  0.703
2004 Sinnayah P, Lindley TE, Staber PD, Davidson BL, Cassell MD, Davisson RL. Targeted viral delivery of Cre recombinase induces conditional gene deletion in cardiovascular circuits of the mouse brain. Physiological Genomics. 18: 25-32. PMID 15069166 DOI: 10.1152/Physiolgenomics.00048.2004  0.415
2004 Alisky JM, Davidson BL. Towards therapy using RNA interference. American Journal of Pharmacogenomics : Genomics-Related Research in Drug Development and Clinical Practice. 4: 45-51. PMID 14987121 DOI: 10.2165/00129785-200404010-00005  0.419
2004 Davidson BL, Paulson HL. Molecular medicine for the brain: silencing of disease genes with RNA interference. The Lancet. Neurology. 3: 145-9. PMID 14980529 DOI: 10.1016/S1474-4422(04)00678-7  0.43
2004 Miller VM, Gouvion CM, Davidson BL, Paulson HL. Targeting Alzheimer's disease genes with RNA interference: an efficient strategy for silencing mutant alleles. Nucleic Acids Research. 32: 661-8. PMID 14754988 DOI: 10.1093/Nar/Gkh208  0.407
2004 Xia H, Mao Q, Eliason SL, Kiewiet N, Critchfield J, Martins IH, Harper SQ, He X, Kotin RM, Zoghbi HY, Orr HT, Paulson HL, Davidson BL. 717. RNAi Therapy for Dominant Neurodegenerative Diseases Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.623  0.686
2004 Liu G, Kotin RM, Chiorini JA, Davidson BL. 230. Neural Progenitor Cell Transduction with AAV Serotypes 1 and 4 Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.178  0.807
2004 Liu G, Chiorini JA, Davidson BL. 229. AAV4 Mediated Gene Transfer in Mucopolysaccharidosis Type VII Mice Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.175  0.805
2004 Harper SQ, Staber PD, Rowley CR, He X, Martins IH, Mao Q, Paulson HL, Davidson BL. 209. Gene Silencing of Human Huntingtin Using Lentivirus-Delivered shRNA Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.150  0.706
2004 Boudreau R, Xia H, Davidson BL. 207. Micro RNAs as Novel siRNA Shuttles Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.148  0.731
2004 Stein CS, Martins I, Davidson BL. 1059. The Lymphocytic Choriomeningitis Virus Envelope Glycoprotein Targets Lentivirus to Neural Progenitors in the Murine Brain Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.1004  0.348
2004 Chen YH, Davidson BL. 93. Targeting AAV to Brain Vascular Endothelium Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.028  0.396
2004 Kang Y, Scheetz TE, Moressi CJ, Tran DT, Xie L, Davidson BL, Casavant TL, McCray PB. 4. In Vitro and In Vivo Analysis of Feline Immunodeficiency Virus-Based Lentiviral Vector Integration|[ast]| Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.05.086  0.358
2003 Davidson BL. Hepatic diseases--hitting the target with inhibitory RNAs. The New England Journal of Medicine. 349: 2357-9. PMID 14668464 DOI: 10.1056/Nejmcibr031609  0.343
2003 Mao Q, Xia H, Davidson BL. Intracellular trafficking of CLN3, the protein underlying the childhood neurodegenerative disease, Batten disease. Febs Letters. 555: 351-7. PMID 14644441 DOI: 10.1016/S0014-5793(03)01274-2  0.361
2003 Lotery AJ, Yang GS, Mullins RF, Russell SR, Schmidt M, Stone EM, Lindbloom JD, Chiorini JA, Kotin RM, Davidson BL. Adeno-associated virus type 5: transduction efficiency and cell-type specificity in the primate retina. Human Gene Therapy. 14: 1663-71. PMID 14633408 DOI: 10.1089/104303403322542301  0.358
2003 Alisky JM, Hughes SM, Davidson BL. Transduction of neurons lining the cerebral external capsules in mice with feline immunodeficiency virus based vectors. Neuroscience Letters. 351: 120-4. PMID 14583396 DOI: 10.1016/S0304-3940(03)00833-4  0.675
2003 Di Pasquale G, Davidson BL, Stein CS, Martins I, Scudiero D, Monks A, Chiorini JA. Identification of PDGFR as a receptor for AAV-5 transduction. Nature Medicine. 9: 1306-12. PMID 14502277 DOI: 10.1038/Nm929  0.341
2003 Gonzalez-Alegre P, Miller VM, Davidson BL, Paulson HL. Toward therapy for DYT1 dystonia: allele-specific silencing of mutant TorsinA. Annals of Neurology. 53: 781-7. PMID 12783425 DOI: 10.1002/Ana.10548  0.426
2003 Miller VM, Xia H, Marrs GL, Gouvion CM, Lee G, Davidson BL, Paulson HL. Allele-specific silencing of dominant disease genes. Proceedings of the National Academy of Sciences of the United States of America. 100: 7195-200. PMID 12782788 DOI: 10.1073/Pnas.1231012100  0.421
2003 Davidson BL, Breakefield XO. Viral vectors for gene delivery to the nervous system. Nature Reviews. Neuroscience. 4: 353-64. PMID 12728263 DOI: 10.1038/Nrn1104  0.407
2003 Sinn PL, Hickey MA, Staber PD, Dylla DE, Jeffers SA, Davidson BL, Sanders DA, McCray PB. Lentivirus vectors pseudotyped with filoviral envelope glycoproteins transduce airway epithelia from the apical surface independently of folate receptor alpha. Journal of Virology. 77: 5902-10. PMID 12719583 DOI: 10.1128/Jvi.77.10.5902-5910.2003  0.307
2003 Smith-Arica JR, Thomson AJ, Ansell R, Chiorini J, Davidson B, McWhir J. Infection efficiency of human and mouse embryonic stem cells using adenoviral and adeno-associated viral vectors. Cloning and Stem Cells. 5: 51-62. PMID 12713701 DOI: 10.1089/153623003321512166  0.36
2003 Mao Q, Foster BJ, Xia H, Davidson BL. Membrane topology of CLN3, the protein underlying Batten disease. Febs Letters. 541: 40-6. PMID 12706816 DOI: 10.1016/S0014-5793(03)00284-9  0.326
2003 Davidson BL, Chiorini JA. Recombinant adeno-associated viral vector types 4 and 5. Preparation and application for CNS gene transfer. Methods in Molecular Medicine. 76: 269-85. PMID 12526169 DOI: 10.1385/1-59259-304-6:269  0.335
2003 Haskell RE, Hughes SM, Chiorini JA, Alisky JM, Davidson BL. Viral-mediated delivery of the late-infantile neuronal ceroid lipofuscinosis gene, TPP-I to the mouse central nervous system. Gene Therapy. 10: 34-42. PMID 12525835 DOI: 10.1038/Sj.Gt.3301843  0.403
2002 Alisky JM, van de Wetering CI, Davidson BL. Widespread dispersal of cholera toxin subunit b to brain and spinal cord neurons following systemic delivery. Experimental Neurology. 178: 139-46. PMID 12460616 DOI: 10.1006/Exnr.2002.8031  0.301
2002 Xia H, Mao Q, Paulson HL, Davidson BL. siRNA-mediated gene silencing in vitro and in vivo. Nature Biotechnology. 20: 1006-10. PMID 12244328 DOI: 10.1038/Nbt739  0.461
2002 Derksen TA, Sauter SL, Davidson BL. Feline immunodeficiency virus vectors. Gene transfer to mouse retina following intravitreal injection. The Journal of Gene Medicine. 4: 463-9. PMID 12221638 DOI: 10.1002/Jgm.267  0.359
2002 Kang Y, Stein CS, Heth JA, Sinn PL, Penisten AK, Staber PD, Ratliff KL, Shen H, Barker CK, Martins I, Sharkey CM, Sanders DA, McCray PB, Davidson BL. In vivo gene transfer using a nonprimate lentiviral vector pseudotyped with Ross River Virus glycoproteins. Journal of Virology. 76: 9378-88. PMID 12186920 DOI: 10.1128/Jvi.76.18.9378-9388.2002  0.374
2002 Yang GS, Schmidt M, Yan Z, Lindbloom JD, Harding TC, Donahue BA, Engelhardt JF, Kotin R, Davidson BL. Virus-mediated transduction of murine retina with adeno-associated virus: effects of viral capsid and genome size. Journal of Virology. 76: 7651-60. PMID 12097579 DOI: 10.1128/Jvi.76.15.7651-7660.2002  0.324
2002 Wang G, Williams G, Xia H, Hickey M, Shao J, Davidson BL, McCray PB. Apical barriers to airway epithelial cell gene transfer with amphotropic retroviral vectors. Gene Therapy. 9: 922-31. PMID 12085240 DOI: 10.1038/Sj.Gt.3301714  0.338
2002 Brooks AI, Stein CS, Hughes SM, Heth J, McCray PM, Sauter SL, Johnston JC, Cory-Slechta DA, Federoff HJ, Davidson BL. Functional correction of established central nervous system deficits in an animal model of lysosomal storage disease with feline immunodeficiency virus-based vectors. Proceedings of the National Academy of Sciences of the United States of America. 99: 6216-21. PMID 11959904 DOI: 10.1073/Pnas.082011999  0.674
2002 Lotery AJ, Derksen TA, Russell SR, Mullins RF, Sauter S, Affatigato LM, Stone EM, Davidson BL. Gene transfer to the nonhuman primate retina with recombinant feline immunodeficiency virus vectors. Human Gene Therapy. 13: 689-96. PMID 11936968 DOI: 10.1089/104303402317322258  0.322
2002 Stein CS, Davidson BL. Gene transfer to the brain using feline immunodeficiency virus-based lentivirus vectors. Methods in Enzymology. 346: 433-54. PMID 11883084 DOI: 10.1016/S0076-6879(02)46070-3  0.329
2002 Sinnayah P, Lindley TE, Staber PD, Cassell MD, Davidson BL, Davisson RL. Selective gene transfer to key cardiovascular regions of the brain: comparison of two viral vector systems. Hypertension. 39: 603-8. PMID 11882616 DOI: 10.1161/Hy0202.103295  0.37
2002 Hughes SM, Moussavi-Harami F, Sauter SL, Davidson BL. Viral-mediated gene transfer to mouse primary neural progenitor cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 5: 16-24. PMID 11786041 DOI: 10.1006/Mthe.2001.0512  0.677
2002 Law LK, Davidson BL. Adenovirus serotype 30 fiber does not mediate transduction via the coxsackie-adenovirus receptor. Journal of Virology. 76: 656-61. PMID 11752156 DOI: 10.1128/Jvi.76.2.656-661.2002  0.599
2001 Xia H, Mao Q, Davidson BL. The HIV Tat protein transduction domain improves the biodistribution of beta-glucuronidase expressed from recombinant viral vectors. Nature Biotechnology. 19: 640-4. PMID 11433275 DOI: 10.1038/90242  0.368
2001 Stein CS, Kang Y, Sauter SL, Townsend K, Staber P, Derksen TA, Martins I, Qian J, Davidson BL, McCray PB. In vivo treatment of hemophilia A and mucopolysaccharidosis type VII using nonprimate lentiviral vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 3: 850-6. PMID 11407898 DOI: 10.1006/Mthe.2001.0325  0.404
2001 Rauma T, Kumpumäki S, Anderson R, Davidson BL, Ruotsalainen H, Myllylä R, Hautala T. Adenoviral gene transfer restores lysyl hydroxylase activity in type VI Ehlers-Danlos syndrome. The Journal of Investigative Dermatology. 116: 602-5. PMID 11286629 DOI: 10.1046/J.1523-1747.2001.01300.X  0.332
2001 Vasquez EC, Beltz TG, Haskell RE, Johnson RF, Meyrelles SS, Davidson BL, Johnson AK. Adenovirus-mediated gene delivery to cells of the magnocellular hypothalamo-neurohypophyseal system. Experimental Neurology. 167: 260-71. PMID 11161614 DOI: 10.1006/Exnr.2000.7557  0.372
2001 Chu Y, Heistad D, Cybulsky MI, Davidson BL. Vascular cell adhesion molecule-1 augments adenovirus-mediated gene transfer. Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 238-42. PMID 11156859 DOI: 10.1161/01.Atv.21.2.238  0.319
2001 Jacobson N, Andrews M, Shepard AR, Nishimura D, Searby C, Fingert JH, Hageman G, Mullins R, Davidson BL, Kwon YH, Alward WL, Stone EM, Clark AF, Sheffield VC. Non-secretion of mutant proteins of the glaucoma gene myocilin in cultured trabecular meshwork cells and in aqueous humor. Human Molecular Genetics. 10: 117-25. PMID 11152659 DOI: 10.1093/Hmg/10.2.117  0.331
2000 Alisky JM, Davidson BL. Gene therapy for amyotrophic lateral sclerosis and other motor neuron diseases. Human Gene Therapy. 11: 2315-29. PMID 11096437 DOI: 10.1089/104303400750038435  0.37
2000 Xia H, Anderson B, Mao Q, Davidson BL. Recombinant human adenovirus: targeting to the human transferrin receptor improves gene transfer to brain microcapillary endothelium. Journal of Virology. 74: 11359-66. PMID 11070036 DOI: 10.1128/Jvi.74.23.11359-11366.2000  0.387
2000 Allamand V, Donahue KM, Straub V, Davisson RL, Davidson BL, Campbell KP. Early adenovirus-mediated gene transfer effectively prevents muscular dystrophy in alpha-sarcoglycan-deficient mice. Gene Therapy. 7: 1385-91. PMID 10981665 DOI: 10.1038/Sj.Gt.3301247  0.347
2000 Alisky JM, Hughes SM, Sauter SL, Jolly D, Dubensky TW, Staber PD, Chiorini JA, Davidson BL. Transduction of murine cerebellar neurons with recombinant FIV and AAV5 vectors. Neuroreport. 11: 2669-73. PMID 10976941 DOI: 10.1097/00001756-200008210-00013  0.358
2000 Lam EW, Hammad HM, Zwacka R, Darby CJ, Baumgardner KR, Davidson BL, Oberley TD, Engelhardt JF, Oberley LW. Immunolocalization and adenoviral vector-mediated manganese superoxide dismutase gene transfer to experimental oral tumors. Journal of Dental Research. 79: 1410-7. PMID 10890721 DOI: 10.1177/00220345000790061001  0.339
2000 Anderson RD, Haskell RE, Xia H, Roessler BJ, Davidson BL. A simple method for the rapid generation of recombinant adenovirus vectors. Gene Therapy. 7: 1034-8. PMID 10871752 DOI: 10.1038/Sj.Gt.3301197  0.328
2000 Leone P, McPhee SW, Janson CG, Davidson BL, Freese A, During MJ. Multi-site partitioned delivery of human tyrosine hydroxylase gene with phenotypic recovery in Parkinsonian rats. Neuroreport. 11: 1145-51. PMID 10817582 DOI: 10.1097/00001756-200004270-00002  0.339
2000 Haskell RE, Carr CJ, Pearce DA, Bennett MJ, Davidson BL. Batten disease: evaluation of CLN3 mutations on protein localization and function. Human Molecular Genetics. 9: 735-44. PMID 10749980 DOI: 10.1093/Hmg/9.5.735  0.312
2000 Zabner J, Seiler M, Walters R, Kotin RM, Fulgeras W, Davidson BL, Chiorini JA. Adeno-associated virus type 5 (AAV5) but not AAV2 binds to the apical surfaces of airway epithelia and facilitates gene transfer. Journal of Virology. 74: 3852-8. PMID 10729159 DOI: 10.1128/Jvi.74.8.3852-3858.2000  0.347
2000 Davidson BL, Stein CS, Heth JA, Martins I, Kotin RM, Derksen TA, Zabner J, Ghodsi A, Chiorini JA. Recombinant adeno-associated virus type 2, 4, and 5 vectors: transduction of variant cell types and regions in the mammalian central nervous system. Proceedings of the National Academy of Sciences of the United States of America. 97: 3428-32. PMID 10688913 DOI: 10.1073/Pnas.050581197  0.403
2000 Wang G, Zabner J, Deering C, Launspach J, Shao J, Bodner M, Jolly DJ, Davidson BL, McCray PB. Increasing epithelial junction permeability enhances gene transfer to airway epithelia In vivo. American Journal of Respiratory Cell and Molecular Biology. 22: 129-38. PMID 10657931 DOI: 10.1165/Ajrcmb.22.2.3938  0.304
1999 Wang G, Slepushkin VA, Bodner M, Zabner J, van Es HH, Thomas P, Jolly DJ, Davidson BL, McCray PB. Keratinocyte growth factor induced epithelial proliferation facilitates retroviral-mediated gene transfer to distal lung epithelia in vivo. The Journal of Gene Medicine. 1: 22-30. PMID 10738582 DOI: 10.1002/(Sici)1521-2254(199901/02)1:1<22::Aid-Jgm1>3.3.Co;2-O  0.315
1999 Ghodsi A, Stein C, Derksen T, Martins I, Anderson RD, Davidson BL. Systemic hyperosmolality improves beta-glucuronidase distribution and pathology in murine MPS VII brain following intraventricular gene transfer. Experimental Neurology. 160: 109-16. PMID 10630195 DOI: 10.1006/Exnr.1999.7205  0.362
1999 Wang G, Slepushkin V, Zabner J, Keshavjee S, Johnston JC, Sauter SL, Jolly DJ, Dubensky TW, Davidson BL, McCray PB. Feline immunodeficiency virus vectors persistently transduce nondividing airway epithelia and correct the cystic fibrosis defect. The Journal of Clinical Investigation. 104: R55-62. PMID 10587528 DOI: 10.1172/Jci8390  0.344
1999 Lam EW, Zwacka R, Seftor EA, Nieva DR, Davidson BL, Engelhardt JF, Hendrix MJ, Oberley LW. Effects of antioxidant enzyme overexpression on the invasive phenotype of hamster cheek pouch carcinoma cells. Free Radical Biology & Medicine. 27: 572-9. PMID 10490277 DOI: 10.1016/S0891-5849(99)00109-4  0.302
1999 Lawrence MS, Foellmer HG, Elsworth JD, Kim JH, Leranth C, Kozlowski DA, Bothwell AL, Davidson BL, Bohn MC, Redmond DE. Inflammatory responses and their impact on beta-galactosidase transgene expression following adenovirus vector delivery to the primate caudate nucleus. Gene Therapy. 6: 1368-79. PMID 10467361 DOI: 10.1038/Sj.Gt.3300958  0.351
1999 Stec DE, Davisson RL, Haskell RE, Davidson BL, Sigmund CD. Efficient liver-specific deletion of a floxed human angiotensinogen transgene by adenoviral delivery of Cre recombinase in vivo. The Journal of Biological Chemistry. 274: 21285-90. PMID 10409686 DOI: 10.1074/Jbc.274.30.21285  0.357
1999 Bohn MC, Choi-Lundberg DL, Davidson BL, Leranth C, Kozlowski DA, Smith JC, O'Banion MK, Redmond DE. Adenovirus-mediated transgene expression in nonhuman primate brain. Human Gene Therapy. 10: 1175-84. PMID 10340549 DOI: 10.1089/10430349950018166  0.356
1999 Johnston JC, Gasmi M, Lim LE, Elder JH, Yee JK, Jolly DJ, Campbell KP, Davidson BL, Sauter SL. Minimum requirements for efficient transduction of dividing and nondividing cells by feline immunodeficiency virus vectors. Journal of Virology. 73: 4991-5000. PMID 10233961 DOI: 10.1128/Jvi.73.6.4991-5000.1999  0.374
1999 Haskell RE, Derksen TA, Davidson BL. Intracellular trafficking of the JNCL protein CLN3. Molecular Genetics and Metabolism. 66: 253-60. PMID 10191111 DOI: 10.1006/Mgme.1999.2802  0.321
1999 Stein CS, Ghodsi A, Derksen T, Davidson BL. Systemic and central nervous system correction of lysosomal storage in mucopolysaccharidosis type VII mice. Journal of Virology. 73: 3424-9. PMID 10074197 DOI: 10.1128/Jvi.73.4.3424-3429.1999  0.337
1999 Chillon M, Bosch A, Zabner J, Law L, Armentano D, Welsh MJ, Davidson BL. Group D adenoviruses infect primary central nervous system cells more efficiently than those from group C. Journal of Virology. 73: 2537-40. PMID 9971839 DOI: 10.1128/Jvi.73.3.2537-2540.1999  0.63
1998 Vasquez EC, Johnson RF, Beltz TG, Haskell RE, Davidson BL, Johnson AK. Replication-deficient adenovirus vector transfer of gfp reporter gene into supraoptic nucleus and subfornical organ neurons. Experimental Neurology. 154: 353-65. PMID 9878173 DOI: 10.1006/Exnr.1998.6917  0.347
1998 Choi-Lundberg DL, Lin Q, Schallert T, Crippens D, Davidson BL, Chang YN, Chiang YL, Qian J, Bardwaj L, Bohn MC. Behavioral and cellular protection of rat dopaminergic neurons by an adenoviral vector encoding glial cell line-derived neurotrophic factor. Experimental Neurology. 154: 261-75. PMID 9878166 DOI: 10.1006/Exnr.1998.6887  0.309
1998 Ghodsi A, Stein C, Derksen T, Yang G, Anderson RD, Davidson BL. Extensive beta-glucuronidase activity in murine central nervous system after adenovirus-mediated gene transfer to brain. Human Gene Therapy. 9: 2331-40. PMID 9829532 DOI: 10.1089/Hum.1998.9.16-2331  0.361
1998 Wang G, Davidson BL, Melchert P, Slepushkin VA, van Es HH, Bodner M, Jolly DJ, McCray PB. Influence of cell polarity on retrovirus-mediated gene transfer to differentiated human airway epithelia. Journal of Virology. 72: 9818-26. PMID 9811717 DOI: 10.1128/Jvi.72.12.9818-9826.1998  0.354
1998 Wang G, Williamson R, Mueller G, Thomas P, Davidson BL, McCray PB. Ultrasound-guided gene transfer to hepatocytes in utero. Fetal Diagnosis and Therapy. 13: 197-205. PMID 9784638 DOI: 10.1159/000020838  0.307
1998 Goebel EA, Davidson BL, Graham SM, Kern JA. Tumor reduction in vivo after adenoviral mediated gene transfer of the herpes simplex virus thymidine kinase gene and ganciclovir treatment in human head and neck squamous cell carcinoma. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery. 119: 331-6. PMID 9781985 DOI: 10.1016/S0194-5998(98)70073-7  0.342
1998 Beer SJ, Matthews CB, Stein CS, Ross BD, Hilfinger JM, Davidson BL. Poly (lactic-glycolic) acid copolymer encapsulation of recombinant adenovirus reduces immunogenicity in vivo. Gene Therapy. 5: 740-6. PMID 9747453 DOI: 10.1038/Sj.Gt.3300647  0.324
1998 Bosch A, McCray PB, Walters KS, Bodner M, Jolly DJ, van Es HH, Nakamura T, Matsumoto K, Davidson BL. Effects of keratinocyte and hepatocyte growth factor in vivo: implications for retrovirus-mediated gene transfer to liver. Human Gene Therapy. 9: 1747-54. PMID 9721085 DOI: 10.1089/Hum.1998.9.12-1747  0.335
1998 Rios CD, Chu Y, Davidson BL, Heistad DD. Ten steps to gene therapy for cardiovascular diseases. The Journal of Laboratory and Clinical Medicine. 132: 104-11. PMID 9708571 DOI: 10.1016/S0022-2143(98)90005-1  0.328
1998 Brooks AI, Halterman MW, Chadwick CA, Davidson BL, Haak-Frendscho M, Radel C, Porter C, Federoff HJ. Reproducible and efficient murine CNS gene delivery using a microprocessor-controlled injector. Journal of Neuroscience Methods. 80: 137-47. PMID 9667386 DOI: 10.1016/S0165-0270(97)00207-0  0.341
1998 Holt KH, Lim LE, Straub V, Venzke DP, Duclos F, Anderson RD, Davidson BL, Campbell KP. Functional rescue of the sarcoglycan complex in the BIO 14.6 hamster using delta-sarcoglycan gene transfer. Molecular Cell. 1: 841-8. PMID 9660967 DOI: 10.1016/S1097-2765(00)80083-0  0.338
1998 Christenson SD, Lake KD, Ooboshi H, Faraci FM, Davidson BL, Heistad DD. Adenovirus-mediated gene transfer in vivo to cerebral blood vessels and perivascular tissue in mice. Stroke; a Journal of Cerebral Circulation. 29: 1411-5; discussion 1. PMID 9660397 DOI: 10.1161/01.Str.29.7.1411  0.326
1998 Betz AL, Shakui P, Davidson BL. Gene transfer to rodent brain with recombinant adenoviral vectors: effects of infusion parameters, infectious titer, and virus concentration on transduction volume. Experimental Neurology. 150: 136-42. PMID 9514831 DOI: 10.1006/Exnr.1997.6755  0.321
1997 Davidson BL, Hilfinger JM, Beer SJ. Extended release of adenovirus from polymer microspheres: potential use in gene therapy for brain tumors. Advanced Drug Delivery Reviews. 27: 59-66. PMID 10837551 DOI: 10.1016/S0169-409X(97)00022-7  0.349
1997 Meyrelles SS, Sharma RV, Whiteis CA, Davidson BL, Chapleau MW. Adenovirus-mediated gene transfer to cultured nodose sensory neurons. Brain Research. Molecular Brain Research. 51: 33-41. PMID 9427504 DOI: 10.1016/S0169-328X(97)00212-X  0.337
1997 O'Connor WM, Davidson BL, Kaplitt MG, Abbey MV, During MJ, Leone P, Langer D, O'Connor MJ, Freese A. Adenovirus vector-mediated gene transfer into human epileptogenic brain slices: prospects for gene therapy in epilepsy. Experimental Neurology. 148: 167-78. PMID 9398459 DOI: 10.1006/Exnr.1997.6658  0.399
1997 Ooboshi H, Rios CD, Chu Y, Christenson SD, Faraci FM, Davidson BL, Heistad DD. Augmented adenovirus-mediated gene transfer to atherosclerotic vessels. Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 1786-92. PMID 9327778 DOI: 10.1161/01.Atv.17.9.1786  0.345
1997 McCray PB, Wang G, Kline JN, Zabner J, Chada S, Jolly DJ, Chang SM, Davidson BL. Alveolar macrophages inhibit retrovirus-mediated gene transfer to airway epithelia. Human Gene Therapy. 8: 1087-93. PMID 9189766 DOI: 10.1089/Hum.1997.8.9-1087  0.331
1997 Davidson BL, Bohn MC. Recombinant adenovirus: a gene transfer vector for study and treatment of CNS diseases. Experimental Neurology. 144: 125-30. PMID 9126161 DOI: 10.1006/Exnr.1996.6398  0.376
1997 Muhonen MG, Ooboshi H, Welsh MJ, Davidson BL, Heistad DD. Gene transfer to cerebral blood vessels after subarachnoid hemorrhage. Stroke; a Journal of Cerebral Circulation. 28: 822-8; discussion 82. PMID 9099203 DOI: 10.1161/01.Str.28.4.822  0.326
1997 Fasbender A, Zabner J, Chillón M, Moninger TO, Puga AP, Davidson BL, Welsh MJ. Complexes of adenovirus with polycationic polymers and cationic lipids increase the efficiency of gene transfer in vitro and in vivo. The Journal of Biological Chemistry. 272: 6479-89. PMID 9045673 DOI: 10.1074/Jbc.272.10.6479  0.351
1997 Lamping KG, Rios CD, Chun JA, Ooboshi H, Davidson BL, Heistad DD. Intrapericardial administration of adenovirus for gene transfer. The American Journal of Physiology. 272: H310-7. PMID 9038951 DOI: 10.1152/Ajpheart.1997.272.1.H310  0.316
1997 Choi-Lundberg DL, Lin Q, Chang YN, Chiang YL, Hay CM, Mohajeri H, Davidson BL, Bohn MC. Dopaminergic neurons protected from degeneration by GDNF gene therapy. Science (New York, N.Y.). 275: 838-41. PMID 9012352 DOI: 10.1126/Science.275.5301.838  0.347
1997 Walter E, Croyle MA, Davidson BL, Roessler BJ, Hilfinger JM, Amidon GL. Adenovirus mediated gene transfer to intestinal epithelial cells as a potential approach for oral delivery of peptides and proteins Journal of Controlled Release. 46: 75-87. DOI: 10.1016/S0168-3659(96)01584-2  0.347
1996 Bosch A, McCray PB, Chang SM, Ulich TR, Simonet WS, Jolly DJ, Davidson BL. Proliferation induced by keratinocyte growth factor enhances in vivo retroviral-mediated gene transfer to mouse hepatocytes. The Journal of Clinical Investigation. 98: 2683-7. PMID 8981911 DOI: 10.1172/Jci119091  0.313
1996 Freese A, During MJ, Davidson BL, Gennarelli TA, Kaplitt MG, Flamm ES, Snyder PJ. Transfection of human lactotroph adenoma cells with an adenovirus vector expressing tyrosine hydroxylase decreases prolactin release. The Journal of Clinical Endocrinology and Metabolism. 81: 2401-4. PMID 8964885 DOI: 10.1210/Jcem.81.6.8964885  0.333
1996 Yao SN, Farjo A, Roessler BJ, Davidson BL, Kurachi K. Adenovirus-mediated transfer of human factor IX gene in immunodeficient and normal mice: evidence for prolonged stability and activity of the transgene in liver. Viral Immunology. 9: 141-53. PMID 8890472 DOI: 10.1089/Vim.1996.9.141  0.38
1996 Plumb TJ, Bosch A, Roessler BJ, Shewach DS, Davidson BL. Hypoxanthine-guanine phosphoribosyltransferase (HPRT) expression in the central nervous system of HPRT-deficient mice following adenoviral-mediated gene transfer. Neuroscience Letters. 214: 159-62. PMID 8878108 DOI: 10.1016/0304-3940(96)12932-3  0.408
1996 Goebel EA, Davidson BL, Zabner J, Graham SM, Kern JA. Adenovirus-mediated gene therapy for head and neck squamous cell carcinomas. The Annals of Otology, Rhinology, and Laryngology. 105: 562-7. PMID 8678435 DOI: 10.1177/000348949610500713  0.349
1995 McCoy RD, Davidson BL, Roessler BJ, Huffnagle GB, Janich SL, Laing TJ, Simon RH. Pulmonary inflammation induced by incomplete or inactivated adenoviral particles. Human Gene Therapy. 6: 1553-60. PMID 8664380 DOI: 10.1089/Hum.1995.6.12-1553  0.318
1995 Doran SE, Ren XD, Betz AL, Pagel MA, Neuwelt EA, Roessler BJ, Davidson BL. Gene expression from recombinant viral vectors in the central nervous system after blood-brain barrier disruption. Neurosurgery. 36: 965-70. PMID 7791989 DOI: 10.1227/00006123-199505000-00012  0.382
1995 Smythe WR, Hwang HC, Elshami AA, Amin KM, Eck SL, Davidson BL, Wilson JM, Kaiser LR, Albelda SM. Treatment of experimental human mesothelioma using adenovirus transfer of the herpes simplex thymidine kinase gene. Annals of Surgery. 222: 78-86. PMID 7618973 DOI: 10.1097/00000658-199507000-00013  0.481
1995 Nilaver G, Muldoon LL, Kroll RA, Pagel MA, Breakefield XO, Davidson BL, Neuwelt EA. Delivery of herpesvirus and adenovirus to nude rat intracerebral tumors after osmotic blood-brain barrier disruption. Proceedings of the National Academy of Sciences of the United States of America. 92: 9829-33. PMID 7568227 DOI: 10.1073/Pnas.92.21.9829  0.307
1995 Ooboshi H, Welsh MJ, Rios CD, Davidson BL, Heistad DD. Adenovirus-mediated gene transfer in vivo to cerebral blood vessels and perivascular tissue. Circulation Research. 77: 7-13. PMID 7540517 DOI: 10.1161/01.Res.77.1.7  0.354
1995 Ríos CD, Ooboshi H, Piegors D, Davidson BL, Heistad DD. Adenovirus-mediated gene transfer to normal and atherosclerotic arteries. A novel approach. Arteriosclerosis, Thrombosis, and Vascular Biology. 15: 2241-5. PMID 7489249 DOI: 10.1161/01.Atv.15.12.2241  0.317
1995 Davidson BL. The limitations of central nervous systemdirected gene transfer Behavioral and Brain Sciences. 18: 54-55. DOI: 10.1017/S0140525X0003733X  0.33
1994 Davidson BL, Doran SE, Shewach DS, Latta JM, Hartman JW, Roessler BJ. Expression of Escherichia coli β-Galactosidase and Rat HPRT in the CNS of Macaca mulatta Following Adenoviral Mediated Gene Transfer Experimental Neurology. 125: 258-267. PMID 8313940 DOI: 10.1006/Exnr.1994.1028  0.37
1994 Roessler BJ, Davidson BL. Direct plasmid mediated transfection of adult murine brain cells in vivo using cationic liposomes. Neuroscience Letters. 167: 5-10. PMID 8177529 DOI: 10.1016/0304-3940(94)91015-4  0.38
1994 Davidson BL, Golovoy N, Roessler BJ. A 13 base pair deletion in exon 1 of HPRTIllinois forms a functional GUG initiation codon. Human Genetics. 93: 300-4. PMID 8125482 DOI: 10.1007/Bf00212027  0.338
1993 Davidson BL, Brown JE, Weber CH, Palella TD, Roessler BJ. Synthesis of normal and variant human hypoxanthine-guanine phosphoribosyltransferase in Escherichia coli. Gene. 123: 271-5. PMID 8428670 DOI: 10.1016/0378-1119(93)90137-R  0.305
1993 Davidson BL, Allen ED, Kozarsky KF, Wilson JM, Roessler BJ. A model system for in vivo gene transfer into the central nervous system using an adenoviral vector. Nature Genetics. 3: 219-23. PMID 8387378 DOI: 10.1038/Ng0393-219  0.494
1993 Roessler BJ, Allen ED, Wilson JM, Hartman JW, Davidson BL. Adenoviral-mediated gene transfer to rabbit synovium in vivo. The Journal of Clinical Investigation. 92: 1085-92. PMID 8349791 DOI: 10.1172/Jci116614  0.487
1992 Davidson BL, Roessler BJ, Palella TD. Expression of normal and variant human hypoxanthine-guanine phosphoribosyltransferase in E. coli. Advances in Experimental Medicine and Biology. 105-8. PMID 1781351 DOI: 10.1007/978-1-4615-7703-4_23  0.301
1991 Tarlé SA, Davidson BL, Wu VC, Zidar FJ, Seegmiller JE, Kelley WN, Palella TD. Determination of the mutations responsible for the Lesch-Nyhan syndrome in 17 subjects. Genomics. 10: 499-501. PMID 2071157 DOI: 10.1016/0888-7543(91)90341-B  0.636
1991 Davidson BL, Tarlé SA, Van Antwerp M, Gibbs DA, Watts RW, Kelley WN, Palella TD. Identification of 17 independent mutations responsible for human hypoxanthine-guanine phosphoribosyltransferase (HPRT) deficiency. American Journal of Human Genetics. 48: 951-8. PMID 2018042  0.469
1989 Fujimori S, Davidson BL, Kelley WN, Palella TD. Identification of a single nucleotide change in the hypoxanthine-guanine phosphoribosyltransferase gene (HPRTYale) responsible for Lesch-Nyhan syndrome. The Journal of Clinical Investigation. 83: 11-3. PMID 2910902 DOI: 10.1172/Jci113846  0.549
1989 Davidson BL, Pashmforoush M, Kelley WN, Palella TD. Human hypoxanthine-guanine phosphoribosyltransferase deficiency. The molecular defect in a patient with gout (HPRTAshville). The Journal of Biological Chemistry. 264: 520-5. PMID 2909537  0.473
1989 Davidson BL, Tarlé SA, Palella TD, Kelley WN. Molecular basis of hypoxanthine-guanine phosphoribosyltransferase deficiency in ten subjects determined by direct sequencing of amplified transcripts. The Journal of Clinical Investigation. 84: 342-6. PMID 2738157 DOI: 10.1172/Jci114160  0.545
1989 Davidson BL, Palella TD, Fujimori S, Kelley WN. Structural consequences of point mutations in nine human HPRT variants. Advances in Experimental Medicine and Biology. 253: 139-43. PMID 2624183 DOI: 10.1007/978-1-4684-5673-8_22  0.519
1989 Fujimori S, Davidson BL, Kelley WN, Palella TD. Lesch-Nyhan syndrome due to a single nucleotide change in the hypoxanthine-guanine phosphoribosyltransferase gene (HPRTYale). Advances in Experimental Medicine and Biology. 253: 135-8. PMID 2624182 DOI: 10.1007/978-1-4684-5673-8_21  0.555
1988 Davidson BL, Pashmforoush M, Kelley WN, Palella TD. Genetic basis of hypoxanthine guanine phosphoribosyltransferase deficiency in a patient with the Lesch-Nyhan syndrome (HPRTFlint). Gene. 63: 331-6. PMID 3384338 DOI: 10.1016/0378-1119(88)90536-7  0.558
1988 Davidson BL, Palella TD, Kelley WN. Human hypoxanthine-guanine phosphoribosyltransferase: a single nucleotide substitution in cDNA clones isolated from a patient with Lesch-Nyhan syndrome (HPRTMidland). Gene. 68: 85-91. PMID 3265398 DOI: 10.1016/0378-1119(88)90601-4  0.526
1988 Davidson BL, Chin SJ, Wilson JM, Kelley WN, Palella TD. Hypoxanthine-guanine phosphoribosyltransferase. Genetic evidence for identical mutations in two partially deficient subjects. The Journal of Clinical Investigation. 82: 2164-7. PMID 3198771 DOI: 10.1172/Jci113839  0.591
1988 Fujimori S, Hidaka Y, Davidson BL, Palella TD, Kelley WN. Identification of a single nucleotide change in a mutant gene for hypoxanthine-guanine phosphoribosyltransferase (HPRT Ann Arbor). Human Genetics. 79: 39-43. PMID 2896620 DOI: 10.1007/Bf00291707  0.534
1988 Fujimori S, Davidson BL, Palella TD, Kelley WN. 38 LESCH-NYHAN SYNDROME DUE TO A SINGLE NUCLEOTIDE CHANGE IN THE HYPOXANTHINE-GUANIJE PHOSPHORIBOSYL-TRANSFERASE GENE (HPRT Yale ) Pediatric Research. 24: 117-117. DOI: 10.1203/00006450-198807000-00062  0.541
1988 Davidson BL, Palella TD, Fujimori S, Kelley WN. 27 Structural Consequences Of Point Mutations In Nine Human Hprt Variants Pediatric Research. 24: 115-115. DOI: 10.1203/00006450-198807000-00051  0.507
1986 Wilson JM, Stout JT, Palella TD, Davidson BL, Kelley WN, Caskey CT. A molecular survey of hypoxanthine-guanine phosphoribosyltransferase deficiency in man. The Journal of Clinical Investigation. 77: 188-95. PMID 3944251 DOI: 10.1172/Jci112275  0.628
1985 Daddona PE, Davidson BL, Perignon JL, Kelley WN. Genetic expression in partial adenosine deaminase deficiency. mRNA levels and protein turnover for the enzyme variants in human B-lymphoblast cell lines. The Journal of Biological Chemistry. 260: 3875-80. PMID 3871777  0.495
1983 Daddona PE, Mitchell BS, Meuwissen HJ, Davidson BL, Wilson JM, Koller CA. Adenosine deaminase deficiency with normal immune function. An acidic enzyme mutation. The Journal of Clinical Investigation. 72: 483-92. PMID 6603477 DOI: 10.1172/Jci110996  0.406
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