Karen O'Malley - Publications

Affiliations: 
Anatomy and Neurobiology Washington University, Saint Louis, St. Louis, MO 

94 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Jong YI, Harmon SK, O'Malley KL. Intracellular GPCRs play key roles in synaptic plasticity. Acs Chemical Neuroscience. PMID 29409317 DOI: 10.1021/acschemneuro.7b00516  0.4
2017 Jong YI, Harmon SK, O'Malley KL. GPCR signaling from within the cell. British Journal of Pharmacology. PMID 28872669 DOI: 10.1111/bph.14023  0.4
2017 Sergin I, Jong YI, Harmon SK, Kumar V, O'Malley KL. Sequences within the C-terminus of the metabotropic glutamate receptor, mGluR5, are responsible for inner nuclear membrane localization. The Journal of Biological Chemistry. PMID 28096465 DOI: 10.1074/jbc.M116.757724  0.48
2016 Jong YI, O'Malley KL. Mechanisms Associated with Activation of Intracellular Metabotropic Glutamate Receptor, mGluR5. Neurochemical Research. PMID 27514643 DOI: 10.1007/s11064-016-2026-6  0.4
2016 Vincent K, Cornea VM, Jong YJ, Laferrière A, Kumar N, Mickeviciute A, Fung JS, Bandegi P, Ribeiro-da-Silva A, O'Malley KL, Coderre TJ. Intracellular mGluR5 plays a critical role in neuropathic pain. Nature Communications. 7: 10604. PMID 26837579 DOI: 10.1038/ncomms10604  1
2015 Dearborn JT, Harmon SK, Fowler SC, O'Malley KL, Taylor GT, Sands MS, Wozniak DF. Comprehensive functional characterization of murine infantile Batten disease including Parkinson-like behavior and dopaminergic markers. Scientific Reports. 5: 12752. PMID 26238334 DOI: 10.1038/srep12752  0.4
2014 Jong YJ, Sergin I, Purgert CA, O'Malley KL. Location-dependent signaling of the group 1 metabotropic glutamate receptor mGlu5. Molecular Pharmacology. 86: 774-85. PMID 25326002 DOI: 10.1124/mol.114.094763  0.48
2014 Lu X, Kim-Han JS, Harmon S, Sakiyama-Elbert SE, O'Malley KL. The Parkinsonian mimetic, 6-OHDA, impairs axonal transport in dopaminergic axons. Molecular Neurodegeneration. 9: 17. PMID 24885281 DOI: 10.1186/1750-1326-9-17  1
2014 Purgert CA, Izumi Y, Jong YJ, Kumar V, Zorumski CF, O'Malley KL. Intracellular mGluR5 can mediate synaptic plasticity in the hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 4589-98. PMID 24672004 DOI: 10.1523/JNEUROSCI.3451-13.2014  1
2013 Bernstein AI, O'Malley KL. MPP+-induces PUMA- and p53-dependent, but ATF3-independent cell death. Toxicology Letters. 219: 93-8. PMID 23500530 DOI: 10.1016/j.toxlet.2013.03.003  1
2013 Burke RE, O'Malley K. Axon degeneration in Parkinson's disease. Experimental Neurology. 246: 72-83. PMID 22285449 DOI: 10.1016/j.expneurol.2012.01.011  1
2012 Pandey N, Fahey MT, Jong YJ, O'Malley KL. Sequences located within the N-terminus of the PD-linked LRRK2 lead to increased aggregation and attenuation of 6-hydroxydopamine-induced cell death. Plos One. 7: e45149. PMID 23028814 DOI: 10.1371/journal.pone.0045149  1
2012 Lu X, Kim-Han JS, O'Malley KL, Sakiyama-Elbert SE. A microdevice platform for visualizing mitochondrial transport in aligned dopaminergic axons. Journal of Neuroscience Methods. 209: 35-9. PMID 22652340 DOI: 10.1016/j.jneumeth.2012.05.021  1
2012 Antenor-Dorsey JA, O'Malley KL. WldS but not Nmnat1 protects dopaminergic neurites from MPP+ neurotoxicity. Molecular Neurodegeneration. 7: 5. PMID 22315973 DOI: 10.1186/1750-1326-7-5  1
2012 Kumar V, Fahey PG, Jong YJ, Ramanan N, O'Malley KL. Activation of intracellular metabotropic glutamate receptor 5 in striatal neurons leads to up-regulation of genes associated with sustained synaptic transmission including Arc/Arg3.1 protein. The Journal of Biological Chemistry. 287: 5412-25. PMID 22179607 DOI: 10.1074/jbc.M111.301366  1
2011 Kim-Han JS, Antenor-Dorsey JA, O'Malley KL. The parkinsonian mimetic, MPP+, specifically impairs mitochondrial transport in dopamine axons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 7212-21. PMID 21562285 DOI: 10.1523/JNEUROSCI.0711-11.2011  1
2009 Jong YJ, Kumar V, O'Malley KL. Intracellular metabotropic glutamate receptor 5 (mGluR5) activates signaling cascades distinct from cell surface counterparts. The Journal of Biological Chemistry. 284: 35827-38. PMID 19840937 DOI: 10.1074/jbc.M109.046276  1
2009 Budelli G, Hage TA, Wei A, Rojas P, Jong YJ, O'Malley K, Salkoff L. Na+-activated K+ channels express a large delayed outward current in neurons during normal physiology. Nature Neuroscience. 12: 745-50. PMID 19412167 DOI: 10.1038/nn.2313  1
2008 Kumar V, Jong YJ, O'Malley KL. Activated nuclear metabotropic glutamate receptor mGlu5 couples to nuclear Gq/11 proteins to generate inositol 1,4,5-trisphosphate-mediated nuclear Ca2+ release. The Journal of Biological Chemistry. 283: 14072-83. PMID 18337251 DOI: 10.1074/jbc.M708551200  1
2007 Kim-Han JS, O'Malley KL. Cell stress induced by the parkinsonian mimetic, 6-hydroxydopamine, is concurrent with oxidation of the chaperone, ERp57, and aggresome formation. Antioxidants & Redox Signaling. 9: 2255-64. PMID 17848102 DOI: 10.1089/ars.2007.1791  1
2007 Jong YJ, Schwetye KE, O'Malley KL. Nuclear localization of functional metabotropic glutamate receptor mGlu1 in HEK293 cells and cortical neurons: role in nuclear calcium mobilization and development. Journal of Neurochemistry. 101: 458-69. PMID 17250682 DOI: 10.1111/j.1471-4159.2006.04382.x  1
2006 Holtz WA, Turetzky JM, Jong YJ, O'Malley KL. Oxidative stress-triggered unfolded protein response is upstream of intrinsic cell death evoked by parkinsonian mimetics. Journal of Neurochemistry. 99: 54-69. PMID 16987235 DOI: 10.1111/j.1471-4159.2006.04025.x  1
2006 Hasbani DM, O'Malley KL. Wld(S) mice are protected against the Parkinsonian mimetic MPTP. Experimental Neurology. 202: 93-9. PMID 16806180 DOI: 10.1016/j.expneurol.2006.05.017  1
2005 Hasbani DM, Perez FA, Palmiter RD, O'Malley KL. Dopamine depletion does not protect against acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9428-33. PMID 16221852 DOI: 10.1523/JNEUROSCI.0130-05.2005  1
2005 Jong YJ, Kumar V, Kingston AE, Romano C, O'Malley KL. Functional metabotropic glutamate receptors on nuclei from brain and primary cultured striatal neurons. Role of transporters in delivering ligand. The Journal of Biological Chemistry. 280: 30469-80. PMID 15958386 DOI: 10.1074/jbc.M501775200  1
2005 Holtz WA, Turetzky JM, O'Malley KL. Microarray expression profiling identifies early signaling transcripts associated with 6-OHDA-induced dopaminergic cell death. Antioxidants & Redox Signaling. 7: 639-48. PMID 15890008 DOI: 10.1089/ars.2005.7.639  1
2004 Gardaneh M, O'Malley KL. Rat tyrosine hydroxylase promoter directs tetracycline-inducible foreign gene expression in dopaminergic cell types. Brain Research. Molecular Brain Research. 126: 173-80. PMID 15249141 DOI: 10.1016/j.molbrainres.2004.04.008  1
2003 O'Malley KL, Liu J, Lotharius J, Holtz W. Targeted expression of BCL-2 attenuates MPP+ but not 6-OHDA induced cell death in dopaminergic neurons. Neurobiology of Disease. 14: 43-51. PMID 13678665 DOI: 10.1016/S0969-9961(03)00013-5  1
2003 Jensen PJ, Alter BJ, O'Malley KL. Alpha-synuclein protects naive but not dbcAMP-treated dopaminergic cell types from 1-methyl-4-phenylpyridinium toxicity. Journal of Neurochemistry. 86: 196-209. PMID 12807439 DOI: 10.1046/j.1471-4159.2003.01835.x  1
2003 O'Malley KL, Jong YJ, Gonchar Y, Burkhalter A, Romano C. Activation of metabotropic glutamate receptor mGlu5 on nuclear membranes mediates intranuclear Ca2+ changes in heterologous cell types and neurons. The Journal of Biological Chemistry. 278: 28210-9. PMID 12736269 DOI: 10.1074/jbc.M300792200  1
2003 Holtz WA, O'Malley KL. Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons. The Journal of Biological Chemistry. 278: 19367-77. PMID 12598533 DOI: 10.1074/jbc.M211821200  1
2002 Romano C, Smout S, Miller JK, O'Malley KL. Developmental regulation of metabotropic glutamate receptor 5b protein in rodent brain. Neuroscience. 111: 693-8. PMID 12031354 DOI: 10.1016/S0306-4522(02)00042-8  1
2002 Kilts JD, Connery HS, Arrington EG, Lewis MM, Lawler CP, Oxford GS, O'Malley KL, Todd RD, Blake BL, Nichols DE, Mailman RB. Functional selectivity of dopamine receptor agonists. II. Actions of dihydrexidine in D2L receptor-transfected MN9D cells and pituitary lactotrophs. The Journal of Pharmacology and Experimental Therapeutics. 301: 1179-89. PMID 12023553 DOI: 10.1124/jpet.301.3.1179  1
2001 Mazarakis ND, Azzouz M, Rohll JB, Ellard FM, Wilkes FJ, Olsen AL, Carter EE, Barber RD, Baban DF, Kingsman SM, Kingsman AJ, O'Malley K, Mitrophanous KA. Rabies virus glycoprotein pseudotyping of lentiviral vectors enables retrograde axonal transport and access to the nervous system after peripheral delivery. Human Molecular Genetics. 10: 2109-21. PMID 11590128  1
2001 Todd RD, O'Malley KL. The dopamine receptor DRD4 gene: are duplications distracting? Trends in Pharmacological Sciences. 22: 55-6. PMID 11166839 DOI: 10.1016/S0165-6147(00)01612-6  1
2001 Romano C, Miller JK, Hyrc K, Dikranian S, Mennerick S, Takeuchi Y, Goldberg MP, O'Malley KL. Covalent and noncovalent interactions mediate metabotropic glutamate receptor mGlu5 dimerization. Molecular Pharmacology. 59: 46-53. PMID 11125023  1
2000 Jackson-Lewis V, Vila M, Djaldetti R, Guegan C, Liberatore G, Liu J, O'Malley KL, Burke RE, Przedborski S. Developmental cell death in dopaminergic neurons of the substantia nigra of mice. The Journal of Comparative Neurology. 424: 476-88. PMID 10906714 DOI: 10.1002/1096-9861(20000828)424:3<476::AID-CNE6>3.0.CO;2-0  1
2000 Cazorla P, Smidt MP, O'Malley KL, Burbach JP. A response element for the homeodomain transcription factor Ptx3 in the tyrosine hydroxylase gene promoter. Journal of Neurochemistry. 74: 1829-37. PMID 10800925 DOI: 10.1046/j.1471-4159.2000.0741829.x  1
1999 Choi WS, Canzoniero LM, Sensi SL, O'Malley KL, Gwag BJ, Sohn S, Kim JE, Oh TH, Lee EB, Oh YJ. Characterization of MPP(+)-induced cell death in a dopaminergic neuronal cell line: role of macromolecule synthesis, cytosolic calcium, caspase, and Bcl-2-related proteins. Experimental Neurology. 159: 274-82. PMID 10486196 DOI: 10.1006/exnr.1999.7133  1
1999 Dalman FC, O'Malley KL. kappa-Opioid tolerance and dependence in cultures of dopaminergic midbrain neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 5750-7. PMID 10407016  1
1999 Choi WS, Yoon SY, Oh TH, Choi EJ, O'Malley KL, Oh YJ. Two distinct mechanisms are involved in 6-hydroxydopamine- and MPP+-induced dopaminergic neuronal cell death: role of caspases, ROS, and JNK. Journal of Neuroscience Research. 57: 86-94. PMID 10397638 DOI: 10.1002/(SICI)1097-4547(19990701)57:1<86::AID-JNR9>3.0.CO;2-E  1
1999 Kim JE, Oh JH, Choi WS, Chang II, Sohn S, Krajewski S, Reed JC, O'Malley KL, Oh YJ. Sequential cleavage of poly(ADP-ribose)polymerase and appearance of a small Bax-immunoreactive protein are blocked by Bcl-X(L) and caspase inhibitors during staurosporine-induced dopaminergic neuronal apoptosis. Journal of Neurochemistry. 72: 2456-63. PMID 10349855 DOI: 10.1046/j.1471-4159.1999.0722456.x  1
1999 Lotharius J, Dugan LL, O'Malley KL. Distinct mechanisms underlie neurotoxin-mediated cell death in cultured dopaminergic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 1284-93. PMID 9952406  1
1998 Oh JH, Choi WS, Kim JE, Seo JW, O'Malley KL, Oh YJ. Overexpression of HA-Bax but not Bcl-2 or Bcl-XL attenuates 6-hydroxydopamine-induced neuronal apoptosis. Experimental Neurology. 154: 193-8. PMID 9875280 DOI: 10.1006/exnr.1998.6923  1
1998 During MJ, Samulski RJ, Elsworth JD, Kaplitt MG, Leone P, Xiao X, Li J, Freese A, Taylor JR, Roth RH, Sladek JR, O'Malley KL, Redmond DE. In vivo expression of therapeutic human genes for dopamine production in the caudates of MPTP-treated monkeys using an AAV vector. Gene Therapy. 5: 820-7. PMID 9747462 DOI: 10.1038/sj.gt.3300650  1
1998 Song S, Wang Y, Bak SY, During MJ, Bryan J, Ashe O, Ullrey DB, Trask LE, Grant FD, O'Malley KL, Riedel H, Goldstein DS, Neve KA, LaHoste GJ, Marshall JF, et al. Modulation of rat rotational behavior by direct gene transfer of constitutively active protein kinase C into nigrostriatal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 4119-32. PMID 9592092  1
1997 Oh YJ, Uhland-Smith A, Kim JE, O'Malley KL. Regions outside of the Bcl-2 homology domains, BH1 and BH2 protect a dopaminergic neuronal cell line from staurosporine-induced cell death. Brain Research. Molecular Brain Research. 51: 133-42. PMID 9427515 DOI: 10.1016/S0169-328X(97)00229-5  1
1997 Oh JH, O'Malley KL, Krajewski S, Reed JC, Oh YJ. Bax accelerates staurosporine-induced but suppresses nigericin-induced neuronal cell death. Neuroreport. 8: 1851-6. PMID 9223064  1
1997 Yamaguchi I, Harmon SK, Todd RD, O'Malley KL. The rat D4 dopamine receptor couples to cone transducin (Galphat2) to inhibit forskolin-stimulated cAMP accumulation. The Journal of Biological Chemistry. 272: 16599-602. PMID 9195972 DOI: 10.1074/jbc.272.26.16599  1
1997 Moffat M, Harmon S, Haycock J, O'Malley KL. L-Dopa and dopamine-producing gene cassettes for gene therapy approaches to Parkinson's disease. Experimental Neurology. 144: 69-73. PMID 9126154 DOI: 10.1006/exnr.1996.6390  1
1997 Song S, Wang Y, Bak SY, Lang P, Ullrey D, Neve RL, O'Malley KL, Geller AI. An HSV-1 vector containing the rat tyrosine hydroxylase promoter enhances both long-term and cell type-specific expression in the midbrain. Journal of Neurochemistry. 68: 1792-803. PMID 9109503  1
1996 Todd RD, Carl J, Harmon S, O'Malley KL, Perlmutter JS. Dynamic changes in striatal dopamine D2 and D3 receptor protein and mRNA in response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) denervation in baboons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 7776-82. PMID 8922433  1
1996 Romano C, Yang WL, O'Malley KL. Metabotropic glutamate receptor 5 is a disulfide-linked dimer. The Journal of Biological Chemistry. 271: 28612-6. PMID 8910492 DOI: 10.1074/jbc.271.45.28612  1
1996 Oh YJ, Swarzenski BC, O'Malley KL. Overexpression of Bcl-2 in a murine dopaminergic neuronal cell line leads to neurite outgrowth. Neuroscience Letters. 202: 161-4. PMID 8848256 DOI: 10.1016/0304-3940(95)12235-4  1
1996 O'Hara CM, Tang L, Taussig R, Todd RD, O'Malley KL. Dopamine D2L receptor couples to G alpha i2 and G alpha i3 but not G alpha i1, leading to the inhibition of adenylate cyclase in transfected cell lines. The Journal of Pharmacology and Experimental Therapeutics. 278: 354-60. PMID 8764370  1
1996 Swarzenski BC, O'Malley KL, Todd RD. PTX-sensitive regulation of neurite outgrowth by the dopamine D3 receptor. Neuroreport. 7: 573-6. PMID 8730832  1
1996 Oh YJ, Moffat M, Wong S, Ullrey D, Geller AI, O'Malley KL. A herpes simplex virus-1 vector containing the rat tyrosine hydroxylase promoter directs cell type-specific expression of beta-galactosidase in cultured rat peripheral neurons. Brain Research. Molecular Brain Research. 35: 227-36. PMID 8717359 DOI: 10.1016/0169-328X(95)00221-D  1
1996 Romano C, van den Pol AN, O'Malley KL. Enhanced early developmental expression of the metabotropic glutamate receptor mGluR5 in rat brain: protein, mRNA splice variants, and regional distribution. The Journal of Comparative Neurology. 367: 403-12. PMID 8698900 DOI: 10.1002/(SICI)1096-9861(19960408)367:3<403::AID-CNE6>3.0.CO;2-9  1
1995 Oh YJ, Wong SC, Moffat M, O'Malley KL. Overexpression of Bcl-2 attenuates MPP+, but not 6-ODHA, induced cell death in a dopaminergic neuronal cell line. Neurobiology of Disease. 2: 157-67. PMID 9173999 DOI: 10.1006/nbdi.1995.0017  1
1995 Geller AI, During MJ, Oh YJ, Freese A, O'Malley K. An HSV-1 vector expressing tyrosine hydroxylase causes production and release of L-dopa from cultured rat striatal cells. Journal of Neurochemistry. 64: 487-96. PMID 7830040  1
1995 Wainwright MS, Perry BD, Won LA, O'Malley KL, Wang WY, Ehrlich ME, Heller A. Immortalized murine striatal neuronal cell lines expressing dopamine receptors and cholinergic properties. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 676-88. PMID 7823171  1
1995 Wong SC, Moffat MA, Coker GT, Merlie JP, O'Malley KL. The 3' flanking region of the human tyrosine hydroxylase gene directs reporter gene expression in peripheral neuroendocrine tissues. Journal of Neurochemistry. 65: 23-31. PMID 7790865  1
1995 Van Leeuwen DH, Eisenstein J, O'Malley K, MacKenzie RG. Characterization of a chimeric human dopamine D3/D2 receptor functionally coupled to adenylyl cyclase in Chinese hamster ovary cells. Molecular Pharmacology. 48: 344-51. PMID 7651368  1
1995 Romano C, Sesma MA, McDonald CT, O'Malley K, Van den Pol AN, Olney JW. Distribution of metabotropic glutamate receptor mGluR5 immunoreactivity in rat brain. The Journal of Comparative Neurology. 355: 455-69. PMID 7636025 DOI: 10.1002/cne.903550310  1
1995 O'Malley KL, Harmon S, Moffat M, Uhland-Smith A, Wong S. The human aromatic L-amino acid decarboxylase gene can be alternatively spliced to generate unique protein isoforms. Journal of Neurochemistry. 65: 2409-16. PMID 7595534  1
1994 Tang L, Todd RD, Heller A, O'Malley KL. Pharmacological and functional characterization of D2, D3 and D4 dopamine receptors in fibroblast and dopaminergic cell lines. The Journal of Pharmacology and Experimental Therapeutics. 268: 495-502. PMID 8301592  1
1994 Tang L, Todd RD, O'Malley KL. Dopamine D2 and D3 receptors inhibit dopamine release. The Journal of Pharmacology and Experimental Therapeutics. 270: 475-9. PMID 8071839  1
1994 Wong SC, Moffat MA, O'Malley KL. Sequences distal to the AP1/E box motif are involved in the cell type-specific expression of the rat tyrosine hydroxylase gene. Journal of Neurochemistry. 62: 1691-7. PMID 7908942  1
1994 MacKenzie RG, VanLeeuwen D, Pugsley TA, Shih YH, Demattos S, Tang L, Todd RD, O'Malley KL. Characterization of the human dopamine D3 receptor expressed in transfected cell lines. European Journal of Pharmacology. 266: 79-85. PMID 7907989 DOI: 10.1016/0922-4106(94)90212-7  1
1994 Swarzenski BC, Tang L, Oh YJ, O'Malley KL, Todd RD. Morphogenic potentials of D2, D3, and D4 dopamine receptors revealed in transfected neuronal cell lines. Proceedings of the National Academy of Sciences of the United States of America. 91: 649-53. PMID 7904756  1
1994 Kaplitt MG, Leone P, Samulski RJ, Xiao X, Pfaff DW, O'Malley KL, During MJ. Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain. Nature Genetics. 8: 148-54. PMID 7842013 DOI: 10.1038/ng1094-148  1
1994 During MJ, Naegele JR, O'Malley KL, Geller AI. Long-term behavioral recovery in parkinsonian rats by an HSV vector expressing tyrosine hydroxylase. Science (New York, N.Y.). 266: 1399-403. PMID 7669103  1
1993 Kang UJ, Fisher LJ, Joh TH, O'Malley KL, Gage FH. Regulation of dopamine production by genetically modified primary fibroblasts. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 5203-11. PMID 7902865  1
1992 O'Malley KL, Harmon S, Tang L, Todd RD. The rat dopamine D4 receptor: sequence, gene structure, and demonstration of expression in the cardiovascular system The New Biologist. 4: 137-146. PMID 1554689  1
1992 Todd RD, Mack KJ, Gandelman KY, Hickok JM, O'Malley KL. Dopamine D2 receptor subtypes couple to different second messenger systems. Neurochemistry International. 20: 23S-26S. PMID 1365431 DOI: 10.1016/0197-0186(92)90206-7  1
1992 Cohen AI, Todd RD, Harmon S, O'Malley KL. Photoreceptors of mouse retinas possess D4 receptors coupled to adenylate cyclase. Proceedings of the National Academy of Sciences of the United States of America. 89: 12093-7. PMID 1334557  1
1991 Parsian A, Todd RD, Devor EJ, O'malley KL, Suarez BK, Reich T, Cloninger CR. Alcoholism and Alleles of the Human D2 Dopamine Receptor Locus: Studies of Association and Linkage Archives of General Psychiatry. 48: 655-663. PMID 2069497 DOI: 10.1001/archpsyc.1991.01810310073013  1
1991 Mack KJ, Todd RD, O'Malley KL. The mouse dopamine D2A receptor gene: sequence homology with the rat and human genes and expression of alternative transcripts. Journal of Neurochemistry. 57: 795-801. PMID 1861151  1
1991 Mack KJ, O'Malley KL, Todd RD. Differential expression of dopaminergic D2 receptor messenger RNAs during development. Brain Research. Developmental Brain Research. 59: 249-51. PMID 1833091 DOI: 10.1016/0165-3806(91)90105-R  1
1991 Gandelman KY, Harmon S, Todd RD, O'Malley KL. Analysis of the structure and expression of the human dopamine D2A receptor gene Journal of Neurochemistry. 56: 1024-1029. PMID 1825222  1
1991 Parsian A, Fisher L, O'Malley KL, Todd RD. A new Taql RFLP within intron 2 of human dopamine D2 receptor gene (DRD2) Nucleic Acids Research. 19: 6977. PMID 1684859  1
1991 Burke WJ, O'Malley KL, Chung HD, Harmon SK, Philip Miller J, Berg L. Effect of pre- and postmortem variables on specific mRNA levels in human brain Molecular Brain Research. 11: 37-41. PMID 1662743 DOI: 10.1016/0169-328X(91)90018-S  1
1990 O'Malley KL, Mack KJ, Gandelman KY, Todd RD. Organization and expression of the rat D2A receptor gene: identification of alternative transcripts and a variant donor splice site. Biochemistry. 29: 1367-71. PMID 2139794  1
1990 Coker GT, Studelska D, Harmon S, Burke W, O'Malley KL. Analysis of tyrosine hydroxylase and insulin transcripts in human neuroendocrine tissues Molecular Brain Research. 8: 93-98. PMID 1976199 DOI: 10.1016/0169-328X(90)90052-F  1
1990 Fitzpatrick PF, Chlumsky LJ, Daubner SC, O'Malley KL. Expression of rat tyrosine hydroxylase in insect tissue culture cells and purification and characterization of the cloned enzyme Journal of Biological Chemistry. 265: 2042-2047. PMID 1967606  1
1989 Wolff JA, Fisher LJ, Xu L, Jinnah HA, Langlais PJ, Iuvone PM, O'Malley KL, Rosenberg MB, Shimohama S, Friedmann T. Grafting fibroblasts genetically modified to produce L-dopa in a rat model of Parkinson disease. Proceedings of the National Academy of Sciences of the United States of America. 86: 9011-4. PMID 2573072 DOI: 10.1073/pnas.86.22.9011  1
1989 Todd RD, O'Malley KL. Population frequencies of tyrosine hydroxylase restriction fragment length polymorphisms in bipolar affective disorder Biological Psychiatry. 25: 626-630. PMID 2563947 DOI: 10.1016/0006-3223(89)90223-0  1
1989 Todd RD, Khurana TS, Sajovic P, Stone KR, O'Malley KL. Cloning of ligand-specific cell lines via gene transfer: Identification of a D2 dopamine receptor subtype Proceedings of the National Academy of Sciences of the United States of America. 86: 10134-10138. PMID 2532359 DOI: 10.1073/pnas.86.24.10134  1
1989 Coker GT, Vinnedge L, O'Malley KL. 8-Br-cAMP inhibits the transient expression of firefly luciferase Febs Letters. 249: 183-185. DOI: 10.1016/0014-5793(89)80620-9  1
1988 Coker GT, Vinnedge L, O'Malley KL. Characterization of rat and human tyrosine hydroxylase genes: Functional expression of both promoters in neuronal and non-neuronal cell types Biochemical and Biophysical Research Communications. 157: 1341-1347. PMID 2905129 DOI: 10.1016/S0006-291X(88)81022-2  1
1988 O'Malley KL, Rotwein P. Human tyrosine hydroxylase and insulin genes are contiguous on chromosome 11 Nucleic Acids Research. 16: 4437-4446. PMID 2898127  1
1988 Ginns EI, Rehavi M, Martin BM, Weller M, O'Malley KL, LaMarca ME, McAllister CG, Paul SM. Expression of human tyrosine hydroxylase cDNA in invertebrate cells using a baculovirus vector Journal of Biological Chemistry. 263: 7406-7410. PMID 2896667  1
1987 Brown ER, Coker GT, O'Malley KL. Organization and evolution of the rat tyrosine hydroxylase gene Biochemistry. 26: 5208-5212. PMID 2889468  1
1986 O'Malley KL. Sequence homology between tyrosine hydroxylase mRNA and a rat adrenal medullary cDNA Journal of Neuroscience Research. 16: 3-12. PMID 2875194  1
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