| Year |
Citation |
Score |
| 2023 |
Jong YI, Izumi Y, Harmon SK, Zorumski CF, O'Malley KL. Striatal mGlu-mediated synaptic plasticity is independently regulated by location-specific receptor pools and divergent signaling pathways. The Journal of Biological Chemistry. 104949. PMID 37354970 DOI: 10.1016/j.jbc.2023.104949 |
0.364 |
|
| 2019 |
Jong YI, Harmon SK, O'Malley KL. Location and cell-type specific bias of metabotropic glutamate receptor, mGlu5, negative allosteric modulators. Acs Chemical Neuroscience. PMID 31609579 DOI: 10.1021/acschemneuro.9b00415 |
0.346 |
|
| 2017 |
Sergin I, Jong YI, Harmon SK, Kumar V, O'Malley KL. Sequences within the C-terminus of the metabotropic glutamate receptor, mGluR5, are responsible for inner nuclear membrane localization. The Journal of Biological Chemistry. PMID 28096465 DOI: 10.1074/Jbc.M116.757724 |
0.741 |
|
| 2016 |
Vincent K, Cornea VM, Jong YJ, Laferrière A, Kumar N, Mickeviciute A, Fung JS, Bandegi P, Ribeiro-da-Silva A, O'Malley KL, Coderre TJ. Intracellular mGluR5 plays a critical role in neuropathic pain. Nature Communications. 7: 10604. PMID 26837579 DOI: 10.1038/Ncomms10604 |
0.569 |
|
| 2014 |
Jong YJ, Sergin I, Purgert CA, O'Malley KL. Location-dependent signaling of the group 1 metabotropic glutamate receptor mGlu5. Molecular Pharmacology. 86: 774-85. PMID 25326002 DOI: 10.1124/Mol.114.094763 |
0.672 |
|
| 2014 |
Purgert CA, Izumi Y, Jong YJ, Kumar V, Zorumski CF, O'Malley KL. Intracellular mGluR5 can mediate synaptic plasticity in the hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 4589-98. PMID 24672004 DOI: 10.1523/Jneurosci.3451-13.2014 |
0.716 |
|
| 2013 |
Bernstein AI, O'Malley KL. MPP+-induces PUMA- and p53-dependent, but ATF3-independent cell death. Toxicology Letters. 219: 93-8. PMID 23500530 DOI: 10.1016/J.Toxlet.2013.03.003 |
0.759 |
|
| 2013 |
Burke RE, O'Malley K. Axon degeneration in Parkinson's disease. Experimental Neurology. 246: 72-83. PMID 22285449 DOI: 10.1016/J.Expneurol.2012.01.011 |
0.302 |
|
| 2012 |
Kumar V, Fahey PG, Jong YJ, Ramanan N, O'Malley KL. Activation of intracellular metabotropic glutamate receptor 5 in striatal neurons leads to up-regulation of genes associated with sustained synaptic transmission including Arc/Arg3.1 protein. The Journal of Biological Chemistry. 287: 5412-25. PMID 22179607 DOI: 10.1074/jbc.M111.301366 |
0.349 |
|
| 2011 |
Bernstein AI, Garrison SP, Zambetti GP, O'Malley KL. 6-OHDA generated ROS induces DNA damage and p53- and PUMA-dependent cell death. Molecular Neurodegeneration. 6: 2. PMID 21211034 DOI: 10.1186/1750-1326-6-2 |
0.756 |
|
| 2009 |
Jong YJ, Kumar V, O'Malley KL. Intracellular metabotropic glutamate receptor 5 (mGluR5) activates signaling cascades distinct from cell surface counterparts. The Journal of Biological Chemistry. 284: 35827-38. PMID 19840937 DOI: 10.1074/jbc.M109.046276 |
0.357 |
|
| 2008 |
Kumar V, Jong YJ, O'Malley KL. Activated nuclear metabotropic glutamate receptor mGlu5 couples to nuclear Gq/11 proteins to generate inositol 1,4,5-trisphosphate-mediated nuclear Ca2+ release. The Journal of Biological Chemistry. 283: 14072-83. PMID 18337251 DOI: 10.1074/jbc.M708551200 |
0.305 |
|
| 2007 |
Kim-Han JS, O'Malley KL. Cell stress induced by the parkinsonian mimetic, 6-hydroxydopamine, is concurrent with oxidation of the chaperone, ERp57, and aggresome formation. Antioxidants & Redox Signaling. 9: 2255-64. PMID 17848102 DOI: 10.1089/ars.2007.1791 |
0.352 |
|
| 2006 |
Holtz WA, Turetzky JM, Jong YJ, O'Malley KL. Oxidative stress-triggered unfolded protein response is upstream of intrinsic cell death evoked by parkinsonian mimetics. Journal of Neurochemistry. 99: 54-69. PMID 16987235 DOI: 10.1111/J.1471-4159.2006.04025.X |
0.759 |
|
| 2006 |
Hasbani DM, O'Malley KL. Wld(S) mice are protected against the Parkinsonian mimetic MPTP. Experimental Neurology. 202: 93-9. PMID 16806180 DOI: 10.1016/J.Expneurol.2006.05.017 |
0.737 |
|
| 2005 |
Hasbani DM, Perez FA, Palmiter RD, O'Malley KL. Dopamine depletion does not protect against acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9428-33. PMID 16221852 DOI: 10.1523/Jneurosci.0130-05.2005 |
0.737 |
|
| 2005 |
Jong YJ, Kumar V, Kingston AE, Romano C, O'Malley KL. Functional metabotropic glutamate receptors on nuclei from brain and primary cultured striatal neurons. Role of transporters in delivering ligand. The Journal of Biological Chemistry. 280: 30469-80. PMID 15958386 DOI: 10.1074/jbc.M501775200 |
0.358 |
|
| 2005 |
Holtz WA, Turetzky JM, O'Malley KL. Microarray expression profiling identifies early signaling transcripts associated with 6-OHDA-induced dopaminergic cell death. Antioxidants & Redox Signaling. 7: 639-48. PMID 15890008 DOI: 10.1089/Ars.2005.7.639 |
0.75 |
|
| 2003 |
O'Malley KL, Liu J, Lotharius J, Holtz W. Targeted expression of BCL-2 attenuates MPP+ but not 6-OHDA induced cell death in dopaminergic neurons. Neurobiology of Disease. 14: 43-51. PMID 13678665 DOI: 10.1016/S0969-9961(03)00013-5 |
0.745 |
|
| 2003 |
O'Malley KL, Jong YJ, Gonchar Y, Burkhalter A, Romano C. Activation of metabotropic glutamate receptor mGlu5 on nuclear membranes mediates intranuclear Ca2+ changes in heterologous cell types and neurons. The Journal of Biological Chemistry. 278: 28210-9. PMID 12736269 DOI: 10.1074/jbc.M300792200 |
0.326 |
|
| 2003 |
Holtz WA, O'Malley KL. Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons. The Journal of Biological Chemistry. 278: 19367-77. PMID 12598533 DOI: 10.1074/Jbc.M211821200 |
0.759 |
|
| 1999 |
Choi WS, Canzoniero LM, Sensi SL, O'Malley KL, Gwag BJ, Sohn S, Kim JE, Oh TH, Lee EB, Oh YJ. Characterization of MPP(+)-induced cell death in a dopaminergic neuronal cell line: role of macromolecule synthesis, cytosolic calcium, caspase, and Bcl-2-related proteins. Experimental Neurology. 159: 274-82. PMID 10486196 DOI: 10.1006/exnr.1999.7133 |
0.317 |
|
| 1999 |
Choi WS, Yoon SY, Oh TH, Choi EJ, O'Malley KL, Oh YJ. Two distinct mechanisms are involved in 6-hydroxydopamine- and MPP+-induced dopaminergic neuronal cell death: role of caspases, ROS, and JNK. Journal of Neuroscience Research. 57: 86-94. PMID 10397638 DOI: 10.1002/(SICI)1097-4547(19990701)57:1<86::AID-JNR9>3.0.CO;2-E |
0.331 |
|
| 1999 |
Lotharius J, Dugan LL, O'Malley KL. Distinct mechanisms underlie neurotoxin-mediated cell death in cultured dopaminergic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 1284-93. PMID 9952406 DOI: 10.1523/Jneurosci.19-04-01284.1999 |
0.365 |
|
| 1998 |
Oh JH, Choi WS, Kim JE, Seo JW, O'Malley KL, Oh YJ. Overexpression of HA-Bax but not Bcl-2 or Bcl-XL attenuates 6-hydroxydopamine-induced neuronal apoptosis. Experimental Neurology. 154: 193-8. PMID 9875280 DOI: 10.1006/exnr.1998.6923 |
0.309 |
|
| 1998 |
Dalman F, Moffat M, O'Malley K. Activation of [Greek small letter kappa]-Opioid Receptors Inhibits Depolarization Induced Release of Dopamine from Midbrain Neurons Anesthesiology. 89: 1158A. DOI: 10.1097/00000542-199809190-00087 |
0.358 |
|
| 1997 |
Oh YJ, Uhland-Smith A, Kim JE, O'Malley KL. Regions outside of the Bcl-2 homology domains, BH1 and BH2 protect a dopaminergic neuronal cell line from staurosporine-induced cell death. Brain Research. Molecular Brain Research. 51: 133-42. PMID 9427515 DOI: 10.1016/S0169-328X(97)00229-5 |
0.31 |
|
| 1995 |
Geller AI, During MJ, Oh YJ, Freese A, O'Malley K. An HSV-1 vector expressing tyrosine hydroxylase causes production and release of L-dopa from cultured rat striatal cells. Journal of Neurochemistry. 64: 487-96. PMID 7830040 DOI: 10.1046/J.1471-4159.1995.64020487.X |
0.303 |
|
| 1995 |
Romano C, Sesma MA, McDonald CT, O'Malley K, Van den Pol AN, Olney JW. Distribution of metabotropic glutamate receptor mGluR5 immunoreactivity in rat brain. The Journal of Comparative Neurology. 355: 455-69. PMID 7636025 DOI: 10.1002/Cne.903550310 |
0.356 |
|
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