Giuseppe Verdile, Ph.D. - Publications

Affiliations: 
School of Biomedical and Sports Science Edith Cowan University 
Area:
Alzheimer's disease

112 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Woodfield A, Porter T, Gilani I, Noordin S, Li QX, Collins S, Martins RN, Maruff P, Masters CL, Rowe CC, Villemagne VL, Dore V, Newsholme P, Laws SM, Verdile G. Insulin resistance, cognition and Alzheimer's disease biomarkers: Evidence that CSF Aβ42 moderates the association between insulin resistance and increased CSF tau levels. Neurobiology of Aging. 114: 38-48. PMID 35381406 DOI: 10.1016/j.neurobiolaging.2022.03.004  0.481
2022 Jayatunga DPW, Hone E, Fernando WMADB, Garg ML, Verdile G, Martins RN. Mitoprotective Effects of a Synergistic Nutraceutical Combination: Basis for a Prevention Strategy Against Alzheimer's Disease. Frontiers in Aging Neuroscience. 13: 781468. PMID 35264941 DOI: 10.3389/fnagi.2021.781468  0.495
2022 Jayatunga DPW, Hone E, Fernando WMADB, Garg ML, Verdile G, Martins RN. A Synergistic Combination of DHA, Luteolin, and Urolithin A Against Alzheimer's Disease. Frontiers in Aging Neuroscience. 14: 780602. PMID 35250535 DOI: 10.3389/fnagi.2022.780602  0.486
2021 Jayatunga DPW, Hone E, Khaira H, Lunelli T, Singh H, Guillemin GJ, Fernando B, Garg ML, Verdile G, Martins RN. Therapeutic Potential of Mitophagy-Inducing Microflora Metabolite, Urolithin A for Alzheimer's Disease. Nutrients. 13. PMID 34836000 DOI: 10.3390/nu13113744  0.496
2021 Fernandez S, Burnham SC, Milicic L, Savage G, Maruff P, Peretti M, Sohrabi HR, Lim YY, Weinborn M, Ames D, Masters CL, Martins RN, Rainey-Smith S, Rowe CC, Salvado O, ... ... Verdile G, et al. Is Associated with Amyloid-β and ε4-Related Cognitive Decline in Cognitively Normal Adults. Journal of Alzheimer's Disease Reports. 5: 111-120. PMID 33782664 DOI: 10.3233/ADR-200246  0.397
2021 Moussavi Nik SH, Porter T, Newman M, Bartlett B, Khan I, Sabale M, Eccles M, Woodfield A, Groth D, Dore V, Villemagne VL, Masters CL, Martins RN, Laws SM, Lardelli M, ... Verdile G, et al. Relevance of a Truncated PRESENILIN 2 Transcript to Alzheimer's Disease and Neurodegeneration. Journal of Alzheimer's Disease : Jad. PMID 33720885 DOI: 10.3233/JAD-201133  0.6
2020 Jayatunga DPW, Hone E, Bharadwaj P, Garg M, Verdile G, Guillemin GJ, Martins RN. Targeting Mitophagy in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 33285629 DOI: 10.3233/JAD-191258  0.451
2020 Pedrini S, Hone E, Gupta VB, James I, Teimouri E, Bush AI, Rowe CC, Villemagne VL, Ames D, Masters CL, Rainey-Smith S, Verdile G, Sohrabi HR, Raida MR, Wenk MR, et al. Plasma High Density Lipoprotein Small Subclass is Reduced in Alzheimer's Disease Patients and Correlates with Cognitive Performance. Journal of Alzheimer's Disease : Jad. PMID 32741823 DOI: 10.3233/Jad-200291  0.604
2020 Bharadwaj P, Solomon T, Sahoo BR, Ignasiak K, Gaskin S, Rowles J, Verdile G, Howard MJ, Bond CS, Ramamoorthy A, Martins RN, Newsholme P. Amylin and beta amyloid proteins interact to form amorphous heterocomplexes with enhanced toxicity in neuronal cells. Scientific Reports. 10: 10356. PMID 32587390 DOI: 10.1038/S41598-020-66602-9  0.57
2020 Teimouri E, Rainey-Smith SR, Bharadwaj P, Verdile G, Martins RN. Amla Therapy as a Potential Modulator of Alzheimer's Disease Risk Factors and Physiological Change. Journal of Alzheimer's Disease : Jad. PMID 32083581 DOI: 10.3233/Jad-191033  0.536
2019 Porter T, Burnham SC, Milicic L, Savage G, Maruff P, Sohrabi HR, Peretti M, Lim YY, Weinborn M, Ames D, Masters CL, Martins RN, Rainey-Smith S, Rowe CC, Salvado O, ... ... Verdile G, et al. val158met is not associated with Aβ-amyloid and ε4 related cognitive decline in cognitively normal older adults. Ibro Reports. 6: 147-152. PMID 31080907 DOI: 10.1016/J.Ibror.2019.05.001  0.519
2019 Sharman MJ, Verdile G, Kirubakaran S, Parenti C, Singh A, Watt G, Karl T, Chang D, Li CG, Münch G. Targeting Inflammatory Pathways in Alzheimer's Disease: A Focus on Natural Products and Phytomedicines. Cns Drugs. PMID 30900203 DOI: 10.1007/S40263-019-00619-1  0.445
2019 Porter T, Burnham SC, Milicic L, Savage G, Maruff P, Lim YY, Ames D, Masters CL, Martins RN, Rainey-Smith S, Rowe CC, Salvado O, Groth D, Verdile G, Villemagne VL, et al. Klotho allele status is not associated with Aβ and APOE ε4-related cognitive decline in preclinical Alzheimer's disease. Neurobiology of Aging. 76: 162-165. PMID 30716541 DOI: 10.1016/J.Neurobiolaging.2018.12.014  0.553
2019 Porter T, Burnham SC, Milicic L, Savage G, Maruff P, Peretti M, Sohrabi HR, Lim YYY, Weinborn M, Ames D, Masters CL, Martins RN, Rainey-Smith SR, Rowe C, Salvado O, ... ... Verdile G, et al. P4-485: SPON1 is associated with Aβ-Amyloid and APOE ε4 related cognitive decline in cognitively normal adults Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.08.031  0.394
2019 Jayatunga DP, Gupta VB, Hone E, Verdile G, Garg ML, Martins RN. P1-098: OPTIMAL CONCENTRATIONS OF LUTEOLIN AND DHA TO EXHIBIT SYNERGISTIC EFFECTS AGAINST Aβ1-42 -INDUCED NEUROTOXICITY Alzheimer's & Dementia. 15: P271-P272. DOI: 10.1016/J.Jalz.2019.06.653  0.465
2018 Porter T, Burnham SC, Savage G, Lim YY, Maruff P, Milicic L, Peretti M, Ames D, Masters CL, Martins RN, Rainey-Smith S, Rowe CC, Salvado O, Taddei K, Groth D, ... Verdile G, et al. A Polygenic Risk Score Derived From Episodic Memory Weighted Genetic Variants Is Associated With Cognitive Decline in Preclinical Alzheimer's Disease. Frontiers in Aging Neuroscience. 10: 423. PMID 30620773 DOI: 10.3389/Fnagi.2018.00423  0.498
2018 Porter T, Burnham SC, Milicic L, Savage G, Maruff P, Lim YY, Li QX, Ames D, Masters CL, Rainey-Smith S, Rowe CC, Salvado O, Groth D, Verdile G, Villemagne VL, et al. Utility of an Alzheimer's Disease Risk-Weighted Polygenic Risk Score for Predicting Rates of Cognitive Decline in Preclinical Alzheimer's Disease: A Prospective Longitudinal Study. Journal of Alzheimer's Disease : Jad. PMID 30412495 DOI: 10.3233/Jad-180713  0.417
2018 Lumsden AL, Rogers JT, Majd S, Newman M, Sutherland GT, Verdile G, Lardelli M. Dysregulation of Neuronal Iron Homeostasis as an Alternative Unifying Effect of Mutations Causing Familial Alzheimer's Disease. Frontiers in Neuroscience. 12: 533. PMID 30150923 DOI: 10.3389/Fnins.2018.00533  0.406
2018 Khan I, Krishnaswamy S, Sabale M, Groth D, Wijaya L, Morici M, Berger I, Schaffitzel C, Fraser PE, Martins RN, Verdile G. Efficient production of a mature and functional gamma secretase protease. Scientific Reports. 8: 12834. PMID 30150752 DOI: 10.1038/S41598-018-30788-W  0.536
2018 Martins RN, Villemagne V, Sohrabi HR, Chatterjee P, Shah TM, Verdile G, Fraser P, Taddei K, Gupta VB, Rainey-Smith SR, Hone E, Pedrini S, Lim WL, Martins I, Frost S, et al. Alzheimer's Disease: A Journey from Amyloid Peptides and Oxidative Stress, to Biomarker Technologies and Disease Prevention Strategies-Gains from AIBL and DIAN Cohort Studies. Journal of Alzheimer's Disease : Jad. 62: 965-992. PMID 29562546 DOI: 10.3233/Jad-171145  0.643
2018 Porter T, Burnham SC, Doré V, Savage G, Bourgeat P, Begemann K, Milicic L, Ames D, Bush AI, Maruff P, Masters CL, Rowe CC, Rainey-Smith S, Martins RN, Groth D, ... Verdile G, et al. KIBRA is associated with accelerated cognitive decline and hippocampal atrophy in APOE ε4-positive cognitively normal adults with high Aβ-amyloid burden. Scientific Reports. 8: 2034. PMID 29391469 DOI: 10.1038/S41598-018-20513-Y  0.623
2018 Porter T, Villemagne VL, Savage G, Milicic L, Lim YY, Maruff P, Masters CL, Ames D, Bush AI, Martins RN, Rainey-Smith S, Rowe CC, Taddei K, Groth D, Verdile G, et al. Cognitive gene risk profile for the prediction of cognitive decline in presymptomatic Alzheimer’s disease Personalized Medicine in Psychiatry. 7: 14-20. DOI: 10.1016/J.Pmip.2018.03.001  0.522
2017 Elaskalani O, Khan I, Morici M, Matthysen C, Sabale M, Martins RN, Verdile G, Metharom P. Oligomeric and fibrillar amyloid beta 42 induce platelet aggregation partially through GPVI. Platelets. 29: 415-420. PMID 29206067 DOI: 10.1080/09537104.2017.1401057  0.448
2017 Laws SM, Gaskin S, Woodfield A, Srikanth V, Bruce D, Fraser PE, Porter T, Newsholme P, Wijesekara N, Burnham S, Doré V, Li QX, Maruff P, Masters CL, Rainey-Smith S, ... ... Verdile G, et al. Insulin resistance is associated with reductions in specific cognitive domains and increases in CSF tau in cognitively normal adults. Scientific Reports. 7: 9766. PMID 28852028 DOI: 10.1016/J.Jalz.2017.06.2000  0.553
2017 Wijesekara N, Ahrens R, Sabale M, Wu L, Ha K, Verdile G, Fraser PE. Amyloid-β and islet amyloid pathologies link Alzheimer disease and type 2 diabetes in a transgenic model. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28808140 DOI: 10.1096/Fj.201700431R  0.464
2017 Asih PR, Tegg ML, Sohrabi H, Carruthers M, Gandy SE, Saad F, Verdile G, Ittner LM, Martins RN. Multiple Mechanisms Linking Type 2 Diabetes and Alzheimer's Disease: Testosterone as a Modifier. Journal of Alzheimer's Disease : Jad. PMID 28655134 DOI: 10.3233/Jad-161259  0.573
2017 Gardener SL, Rainey-Smith SR, Sohrabi HR, Weinborn M, Verdile G, Fernando WM, Lim YY, Harrington K, Burnham S, Taddei K, Masters CL, Macaulay SL, Rowe CC, Ames D, Maruff P, et al. Increased Carbohydrate Intake is Associated with Poorer Performance in Verbal Memory and Attention in an APOE Genotype-Dependent Manner. Journal of Alzheimer's Disease : Jad. PMID 28387666 DOI: 10.3233/Jad-161158  0.525
2017 Bharadwaj P, Wijesekara N, Liyanapathirana M, Newsholme P, Ittner L, Fraser P, Verdile G. The Link between Type 2 Diabetes and Neurodegeneration: Roles for Amyloid-β, Amylin, and Tau Proteins. Journal of Alzheimer's Disease : Jad. PMID 28269785 DOI: 10.3233/Jad-161192  0.411
2017 Shah TM, Weinborn M, Verdile G, Sohrabi HR, Martins RN. Enhancing Cognitive Functioning in Healthly Older Adults: a Systematic Review of the Clinical Significance of Commercially Available Computerized Cognitive Training in Preventing Cognitive Decline. Neuropsychology Review. PMID 28092015 DOI: 10.1007/S11065-016-9338-9  0.456
2016 Gardener SL, Sohrabi HR, Shen KK, Rainey-Smith SR, Weinborn M, Bates KA, Shah T, Foster JK, Lenzo N, Salvado O, Laske C, Laws SM, Taddei K, Verdile G, Martins RN. Cerebral Glucose Metabolism is Associated with Verbal but not Visual Memory Performance in Community-Dwelling Older Adults. Journal of Alzheimer's Disease : Jad. PMID 27031482 DOI: 10.3233/Jad-151084  0.416
2016 Bird SM, Sohrabi HR, Sutton TA, Weinborn M, Rainey-Smith SR, Brown B, Patterson L, Taddei K, Gupta V, Carruthers M, Lenzo N, Knuckey N, Bucks RS, Verdile G, Martins RN. Cerebral amyloid-β accumulation and deposition following traumatic brain injury-A narrative review and meta-analysis of animal studies. Neuroscience and Biobehavioral Reviews. PMID 26899257 DOI: 10.1016/J.Neubiorev.2016.01.004  0.537
2016 Porter T, Bharadwaj P, Groth D, Paxman A, Laws SM, Martins RN, Verdile G. The Effects of Latrepirdine on Amyloid-β Aggregation and Toxicity. Journal of Alzheimer's Disease : Jad. PMID 26836170 DOI: 10.3233/Jad-150790  0.548
2015 Verdile G, Keane KN, Cruzat VF, Medic S, Sabale M, Rowles J, Wijesekara N, Martins RN, Fraser PE, Newsholme P. Inflammation and Oxidative Stress: The Molecular Connectivity between Insulin Resistance, Obesity, and Alzheimer's Disease. Mediators of Inflammation. 2015: 105828. PMID 26693205 DOI: 10.1155/2015/105828  0.517
2015 Goozee KG, Shah TM, Sohrabi HR, Rainey-Smith SR, Brown B, Verdile G, Martins RN. Examining the potential clinical value of curcumin in the prevention and diagnosis of Alzheimer's disease. The British Journal of Nutrition. 1-17. PMID 26652155 DOI: 10.1017/S0007114515004687  0.533
2015 Wahjoepramono EJ, Asih PR, Aniwiyanti V, Taddei K, Dhaliwal SS, Fuller SJ, Foster J, Carruthers M, Verdile G, Sohrabi HR, Martins RN. The Effects of Testosterone Supplementation on Cognitive Functioning in Older Men. Cns & Neurological Disorders Drug Targets. PMID 26553159 DOI: 10.2174/1871527315666151110125704  0.452
2015 Barr RK, Verdile G, Wijaya LK, Morici M, Taddei K, Gupta VB, Pedrini S, Jin L, Nicolazzo JA, Knock E, Fraser PE, Martins RN. Validation and Characterisation of a Novel Peptide that Binds Monomeric and Aggregated Beta-amyloid and Inhibits the Formation of Neurotoxic Oligomers. The Journal of Biological Chemistry. PMID 26538562 DOI: 10.1074/Jbc.M115.679993  0.546
2015 Verdile G, Asih PR, Barron AM, Wahjoepramono EJ, Ittner LM, Martins RN. The impact of luteinizing hormone and testosterone on beta amyloid (Aβ) accumulation: Animal and human clinical studies. Hormones and Behavior. PMID 26122291 DOI: 10.1016/J.Yhbeh.2015.05.020  0.6
2015 Verdile G, Fuller SJ, Martins RN. The role of type 2 diabetes in neurodegeneration. Neurobiology of Disease. PMID 25926349 DOI: 10.1016/J.Nbd.2015.04.008  0.539
2015 Asih PR, Wahjoepramono EJ, Aniwiyanti V, Wijaya LK, de Ruyck K, Taddei K, Fuller SJ, Sohrabi H, Dhaliwal SS, Verdile G, Carruthers M, Martins RN. Testosterone replacement therapy in older male subjective memory complainers: double-blind randomized crossover placebo-controlled clinical trial of physiological assessment and safety. Cns & Neurological Disorders Drug Targets. 14: 576-86. PMID 25921747 DOI: 10.2174/1871527314666150429112112  0.483
2015 Moussavi Nik SH, Newman M, Wilson L, Ebrahimie E, Wells S, Musgrave I, Verdile G, Martins RN, Lardelli M. Alzheimer's disease-related peptide PS2V plays ancient, conserved roles in suppression of the unfolded protein response under hypoxia and stimulation of γ-secretase activity. Human Molecular Genetics. 24: 3662-78. PMID 25814654 DOI: 10.1093/Hmg/Ddv110  0.572
2014 Shah T, Verdile G, Sohrabi H, Campbell A, Putland E, Cheetham C, Dhaliwal S, Weinborn M, Maruff P, Darby D, Martins RN. A combination of physical activity and computerized brain training improves verbal memory and increases cerebral glucose metabolism in the elderly. Translational Psychiatry. 4: e487. PMID 25463973 DOI: 10.1038/Tp.2014.122  0.446
2014 Asih PR, Chatterjee P, Verdile G, Gupta VB, Trengove RD, Martins RN. Clearing the amyloid in Alzheimer's: progress towards earlier diagnosis and effective treatments - an update for clinicians. Neurodegenerative Disease Management. 4: 363-78. PMID 25405650 DOI: 10.2217/Nmt.14.29  0.59
2014 Moussavi Nik SH, Newman M, Ganesan S, Chen M, Martins R, Verdile G, Lardelli M. Hypoxia alters expression of zebrafish microtubule-associated protein tau (mapta, maptb) gene transcripts. Bmc Research Notes. 7: 767. PMID 25359609 DOI: 10.1186/1756-0500-7-767  0.491
2014 Kanyenda LJ, Verdile G, Martins R, Meloni BP, Chieng J, Mastaglia F, Laws SM, Anderton RS, Boulos S. Is cholesterol and amyloid-β stress induced CD147 expression a protective response? Evidence that extracellular cyclophilin a mediated neuroprotection is reliant on CD147. Journal of Alzheimer's Disease : Jad. 39: 545-56. PMID 24217276 DOI: 10.3233/Jad-131442  0.389
2014 Newman M, Wilson L, Verdile G, Lim A, Khan I, Moussavi Nik SH, Pursglove S, Chapman G, Martins RN, Lardelli M. Differential, dominant activation and inhibition of Notch signalling and APP cleavage by truncations of PSEN1 in human disease. Human Molecular Genetics. 23: 602-17. PMID 24101600 DOI: 10.1093/Hmg/Ddt448  0.572
2014 Verdile G, Laws SM, Henley D, Ames D, Bush AI, Ellis KA, Faux NG, Gupta VB, Li QX, Masters CL, Pike KE, Rowe CC, Szoeke C, Taddei K, Villemagne VL, et al. Associations between gonadotropins, testosterone and β amyloid in men at risk of Alzheimer's disease. Molecular Psychiatry. 19: 69-75. PMID 23089633 DOI: 10.1038/Mp.2012.147  0.654
2014 Sharman M, Ong D, Verdile G, Munch G, Wenk M, Halliwell B, Martins R. Effect of nutritional supplement therapies in the prevention of Alzheimer’s disease in a transgenic mouse model Journal of Nutrition & Intermediary Metabolism. 1: 32. DOI: 10.1016/J.Jnim.2014.10.113  0.492
2014 Asih PR, Barron AM, Ji B, Katsifis A, Mattner F, Verdile G, Gupta VB, Trengove R, Martins RN. Novel Translocator Protein (Tspo) Ligands For The Potential Treatment Of Alzheimer'S Disease: A Next Generation Alternative To Conventional Hormone Therapy Alzheimers & Dementia. 10. DOI: 10.1016/J.Jalz.2014.05.1715  0.35
2014 Asih PR, Wahjoepramono EJ, Aniwiyanti V, Taddei K, Fuller S, Sohrabi HR, Dhaliwal S, Verdile G, Carruthers M, Martins RN. P3-389: PHYSIOLOGICAL EFFECTS AND SAFETY ASSESSMENT OF TESTOSTERONE REPLACEMENT THERAPY IN OLDER MALE SUBJECTIVE MEMORY COMPLAINERS Alzheimer's & Dementia. 10: P772-P772. DOI: 10.1016/J.Jalz.2014.05.1483  0.4
2014 Wilson AC, Garin S, Porter TLS, Verdile G, Groth DM, Villemagne VL, Ames D, Bush AI, Ellis KA, Macaulay L, Masters CL, Rainey-Smith SR, Rembach A, Rowe C, Taddei K, et al. Genetic Analysis Of The Steroidogenesis Pathway: Associations With Alzheimer'S Disease Risk And Related Phenotypes Alzheimers & Dementia. 10: 667. DOI: 10.1016/J.Jalz.2014.05.1195  0.546
2014 Laws SM, Porter T, Creegan R, Lim WLF, Verdile G, Groth DM, Villemagne V, Wilson AC, Ames D, Bush AI, Ellis KA, Macaulay L, Masters CL, Rainey-Smith SL, Rembach A, et al. Genetic Variation Within Genes Of The Sphingolipid Metabolism Pathway And Their Association With Alzheimer'S Disease Risk And Related Phenotypes Alzheimers & Dementia. 10. DOI: 10.1016/J.Jalz.2014.05.1110  0.493
2013 Bharadwaj PR, Bates KA, Porter T, Teimouri E, Perry G, Steele JW, Gandy S, Groth D, Martins RN, Verdile G. Latrepirdine: molecular mechanisms underlying potential therapeutic roles in Alzheimer's and other neurodegenerative diseases. Translational Psychiatry. 3: e332. PMID 24301650 DOI: 10.1038/Tp.2013.97  0.547
2013 Sharman MJ, Moussavi Nik SH, Chen MM, Ong D, Wijaya L, Laws SM, Taddei K, Newman M, Lardelli M, Martins RN, Verdile G. The Guinea Pig as a Model for Sporadic Alzheimer's Disease (AD): The Impact of Cholesterol Intake on Expression of AD-Related Genes. Plos One. 8: e66235. PMID 23805206 DOI: 10.1371/Journal.Pone.0066235  0.547
2013 Lim WL, Lam SM, Shui G, Mondal A, Ong D, Duan X, Creegan R, Martins IJ, Sharman MJ, Taddei K, Verdile G, Wenk MR, Martins RN. Effects of a high-fat, high-cholesterol diet on brain lipid profiles in apolipoprotein E ε3 and ε4 knock-in mice. Neurobiology of Aging. 34: 2217-24. PMID 23601809 DOI: 10.1016/J.Neurobiolaging.2013.03.012  0.435
2013 Steele JW, Ju S, Lachenmayer ML, Liken J, Stock A, Kim SH, Delgado LM, Alfaro IE, Bernales S, Verdile G, Bharadwaj P, Gupta V, Barr R, Friss A, Dolios G, et al. Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain. Molecular Psychiatry. 18: 882-8. PMID 22869031 DOI: 10.1038/Mp.2012.115  0.512
2013 Steele JW, Lachenmayer ML, Ju S, Stock A, Liken J, Kim SH, Delgado LM, Alfaro IE, Bernales S, Verdile G, Bharadwaj P, Gupta V, Barr R, Friss A, Dolios G, et al. Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model. Molecular Psychiatry. 18: 889-97. PMID 22850627 DOI: 10.1038/Mp.2012.106  0.558
2012 Avdesh A, Chen M, Martin-Iverson MT, Mondal A, Ong D, Rainey-Smith S, Taddei K, Lardelli M, Groth DM, Verdile G, Martins RN. Regular care and maintenance of a zebrafish (Danio rerio) laboratory: an introduction. Journal of Visualized Experiments : Jove. e4196. PMID 23183629 DOI: 10.3791/4196  0.396
2012 Bharadwaj PR, Verdile G, Barr RK, Gupta V, Steele JW, Lachenmayer ML, Yue Z, Ehrlich ME, Petsko G, Ju S, Ringe D, Sankovich SE, Caine JM, Macreadie IG, Gandy S, et al. Latrepirdine (dimebon) enhances autophagy and reduces intracellular GFP-Aβ42 levels in yeast. Journal of Alzheimer's Disease : Jad. 32: 949-67. PMID 22903131 DOI: 10.3233/Jad-2012-120178  0.53
2012 Avdesh A, Martin-Iverson MT, Mondal A, Chen M, Askraba S, Morgan N, Lardelli M, Groth DM, Verdile G, Martins RN. Evaluation of color preference in zebrafish for learning and memory. Journal of Alzheimer's Disease : Jad. 28: 459-69. PMID 22008261 DOI: 10.3233/Jad-2011-110704  0.408
2012 Laws SM, Verdile G, Doecke J, Martins RN. Diagnostic and therapeutic approaches to alzheimer’s disease Pathology. 44: S17. DOI: 10.1016/S0031-3025(16)32639-3  0.541
2012 Shah T, Verdile G, Sohrabi H, Martins R. P1-129: Physical activity and cognitive stimulation improve cognition and alter levels of plasma beta-amyloid in healthy elderly Alzheimer's & Dementia. 8: P151-P151. DOI: 10.1016/J.Jalz.2012.05.406  0.493
2012 Shah T, Verdile G, Sohrabi H, Martins R. O1-08-03: Cross-training of auditory and visual brain training software program improves cognition and alters plasma BDNF levels in healthy older adults Alzheimer's & Dementia. 8: P99-P99. DOI: 10.1016/J.Jalz.2012.05.247  0.408
2012 Chen M, Tegg M, Avdesh A, Mondal A, Lardelli M, Verdile G, Martins R. P4-121: Analysis of insulin-degrading enzyme (IDE) expression and function in zebrafish embryos Alzheimer's & Dementia. 8: P674-P674. DOI: 10.1016/J.Jalz.2012.05.1824  0.392
2012 Bharadwaj P, Verdile G, Caine J, Macreadie I, Martins R. A yeast model for studying intracellular clearance of beta-amyloid 42 Alzheimers & Dementia. 8: 642. DOI: 10.1016/J.Jalz.2012.05.1716  0.484
2012 Verdile G, Sharman M, Chen M, Nik SM, Ong D, Wijaya L, Morgan N, Lardelli M, Martins R. P3-059: The impact of cholesterol intake on expression of Alzheimer's disease-related genes in the guinea pig brain Alzheimer's & Dementia. 8: P474-P475. DOI: 10.1016/J.Jalz.2012.05.1278  0.5
2011 Wahjoepramono EJ, Wijaya LK, Taddei K, Bates KA, Howard M, Martins G, deRuyck K, Matthews PM, Verdile G, Martins RN. Direct exposure of guinea pig CNS to human luteinizing hormone increases cerebrospinal fluid and cerebral beta amyloid levels. Neuroendocrinology. 94: 313-22. PMID 21985789 DOI: 10.1159/000330812  0.519
2011 Kanyenda LJ, Verdile G, Boulos S, Krishnaswamy S, Taddei K, Meloni BP, Mastaglia FL, Martins RN. The dynamics of CD147 in Alzheimer's disease development and pathology. Journal of Alzheimer's Disease : Jad. 26: 593-605. PMID 21694447 DOI: 10.3233/Jad-2011-110584  0.495
2011 Pike KE, Ellis KA, Villemagne VL, Good N, Chételat G, Ames D, Szoeke C, Laws SM, Verdile G, Martins RN, Masters CL, Rowe CC. Cognition and beta-amyloid in preclinical Alzheimer's disease: data from the AIBL study. Neuropsychologia. 49: 2384-90. PMID 21529702 DOI: 10.1016/J.Neuropsychologia.2011.04.012  0.54
2011 Sohrabi HR, Weinborn M, Badcock J, Bates KA, Clarnette R, Trivedi D, Verdile G, Sutton T, Lenzo NP, Gandy SE, Martins RN. New lexicon and criteria for the diagnosis of Alzheimer's disease. The Lancet. Neurology. 10: 299-300; author repl. PMID 21435594 DOI: 10.1016/S1474-4422(11)70056-4  0.542
2011 Newman M, Verdile G, Martins RN, Lardelli M. Zebrafish as a tool in Alzheimer's disease research. Biochimica Et Biophysica Acta. 1812: 346-52. PMID 20920580 DOI: 10.1016/J.Bbadis.2010.09.012  0.508
2011 Avdesh A, Martin-Iverson M, Chen M, Groth D, Mondal A, Morgan N, Lardelli M, Martins R, Verdile G. Evaluation of color preference in zebrafish: A possible potential model for learning and memory disorders Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.311  0.379
2011 Morici M, Martins I, Taddei K, Martins R, Verdile G, Wijaya L, Sharman M, Berger T. O1-03-06: Peripheral clearance of intravenously injected Aß42 is APOE genotype-specific in chow-fed mice but not cholesterol-fed mice Alzheimer's & Dementia. 7: S99-S99. DOI: 10.1016/J.Jalz.2011.05.244  0.394
2011 Macreadie I, Verdile G, Martins R. P2-300: Targets of Aβ-induced activation of mTOR pathway in yeast model Alzheimer's & Dementia. 7: S406-S407. DOI: 10.1016/J.Jalz.2011.05.1178  0.462
2010 Barron AM, Verdile G, Taddei K, Bates KA, Martins RN. Effect of chronic hCG administration on Alzheimer's-related cognition and A beta accumulation in PS1KI mice. Endocrinology. 151: 5380-8. PMID 20844010 DOI: 10.1210/En.2009-1168  0.571
2010 Newman M, Wilson L, Camp E, Verdile G, Martins R, Lardelli M. A zebrafish melanophore model of amyloid beta toxicity. Zebrafish. 7: 155-9. PMID 20515319 DOI: 10.1089/Zeb.2009.0628  0.5
2010 Rodrigues MA, Foster JK, Verdile G, Joesbury K, Prince R, Devine A, Mehta P, Beilby J, Martins RN. Predicting memory decline as a risk factor for Alzheimer's disease in older post-menopausal women: quod erat demonstrandum? International Psychogeriatrics / Ipa. 22: 332-5. PMID 19814842 DOI: 10.1017/S1041610209991190  0.47
2010 Taddei K, Laws SM, Verdile G, Munns S, D'Costa K, Harvey AR, Martins IJ, Hill F, Levy E, Shaw JE, Martins RN. Novel phage peptides attenuate beta amyloid-42 catalysed hydrogen peroxide production and associated neurotoxicity. Neurobiology of Aging. 31: 203-14. PMID 18472186 DOI: 10.1016/J.Neurobiolaging.2008.03.023  0.479
2010 Martins RN, Gandy SE, Gupta V, Steele JW, Kim SH, Cirrito J, Lachenmayer L, Ehrlich M, Yue Z, Bharadwaj P, Barr R, Martins I, Morici M, Taddei K, Verdile G. P3-409: Effects of latrepirdine on Aβ clearance, neurotoxicity and aggregation Alzheimer's & Dementia. 6: S572-S573. DOI: 10.1016/J.Jalz.2010.05.1952  0.504
2010 Bharadwaj PR, Barr R, Lachenmayer L, Steele JW, Ehrlich ME, Yue Z, Gandy S, Verdile G, Martins R. P3-377: Latrepirdine enhances Aβ degradation in yeast via an autophagic pathway Alzheimer's & Dementia. 6: S562-S563. DOI: 10.1016/J.Jalz.2010.05.1919  0.489
2010 Gupta VB, Bhardawaj P, Steele J, Taddei K, Morici M, Gandy S, Verdile G, Martins R. P3-324: Latrepirdine modulates Aβ oligomer formation and attenuates oligomer-associated toxicity Alzheimer's & Dementia. 6: S547-S547. DOI: 10.1016/J.Jalz.2010.05.1825  0.503
2010 Laws SM, Verdile G, Ames D, Bush AI, Ellis KA, Gupta V, Lui JK, Masters CL, Rowe CC, Szoeke C, Taddei K, Villemagne VL, Martins RN. Associations between gonadotropins, testosterone, plasma Aβ and PiB retention in men with subjective memory complaints or mild cognitive impairment Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.1708  0.501
2009 Martins IJ, Berger T, Sharman MJ, Verdile G, Fuller SJ, Martins RN. Cholesterol metabolism and transport in the pathogenesis of Alzheimer's disease. Journal of Neurochemistry. 111: 1275-308. PMID 20050287 DOI: 10.1111/J.1471-4159.2009.06408.X  0.547
2009 Krishnaswamy S, Verdile G, Groth D, Kanyenda L, Martins RN. The structure and function of Alzheimer's gamma secretase enzyme complex. Critical Reviews in Clinical Laboratory Sciences. 46: 282-301. PMID 19958215 DOI: 10.3109/10408360903335821  0.521
2009 Nornes S, Newman M, Wells S, Verdile G, Martins RN, Lardelli M. Independent and cooperative action of Psen2 with Psen1 in zebrafish embryos. Experimental Cell Research. 315: 2791-801. PMID 19563801 DOI: 10.1016/J.Yexcr.2009.06.023  0.446
2009 Barron AM, Cake M, Verdile G, Martins RN. Ovariectomy and 17beta-estradiol replacement do not alter beta-amyloid levels in sheep brain. Endocrinology. 150: 3228-36. PMID 19282379 DOI: 10.1210/En.2008-1252  0.534
2009 Foster JK, Verdile G, Bates KA, Martins RN. Immunization in Alzheimer's disease: naïve hope or realistic clinical potential? Molecular Psychiatry. 14: 239-51. PMID 18957942 DOI: 10.1038/Mp.2008.115  0.527
2009 Bates KA, Verdile G, Li QX, Ames D, Hudson P, Masters CL, Martins RN. Clearance mechanisms of Alzheimer's amyloid-beta peptide: implications for therapeutic design and diagnostic tests. Molecular Psychiatry. 14: 469-86. PMID 18794889 DOI: 10.1038/Mp.2008.96  0.576
2009 Bates KA, Verdile G, Li Q, Ames D, Hudson P, Masters CL, Martins RN. Erratum: Clearance mechanisms of Alzheimer's amyloid-β peptide: implications for therapeutic design and diagnostic tests Molecular Psychiatry. 14: 1144-1144. DOI: 10.1038/Mp.2008.123  0.496
2009 Wijaya LK, Wahjoepramono EJ, Taddei K, Martins G, Howard M, Bates K, Dhaliwal S, Verdile G, Martins R. P1-029: Effect of cortical placement of luteinizing hormone on Aβ metabolism in guinea pigs Alzheimer's & Dementia. 5: P180-P180. DOI: 10.1016/J.Jalz.2009.04.032  0.468
2008 Chan HW, Liu T, Verdile G, Bishop G, Haasl RJ, Smith MA, Perry G, Martins RN, Atwood CS. Copper Induces Apoptosis of Neuroblastoma Cells Via Post-translational Regulation of the Expression of Bcl-2-family Proteins and the tx Mouse is a Better Model of Hepatic than Brain Cu Toxicity. International Journal of Clinical and Experimental Medicine. 1: 76-88. PMID 19079689  0.719
2008 Wahjoepramono EJ, Wijaya LK, Taddei K, Martins G, Howard M, de Ruyck K, Bates K, Dhaliwal SS, Verdile G, Carruthers M, Martins RN. Distinct effects of testosterone on plasma and cerebrospinal fluid amyloid-beta levels. Journal of Alzheimer's Disease : Jad. 15: 129-37. PMID 18780973 DOI: 10.3233/Jad-2008-15111  0.514
2008 Gnjec A, D'Costa KJ, Laws SM, Hedley R, Balakrishnan K, Taddei K, Martins G, Paton A, Verdile G, Gandy SE, Broe GA, Brooks WS, Bennett H, Piguet O, Price P, et al. Association of alleles carried at TNFA -850 and BAT1 -22 with Alzheimer's disease. Journal of Neuroinflammation. 5: 36. PMID 18715507 DOI: 10.1186/1742-2094-5-36  0.542
2008 Verdile G, Yeap BB, Clarnette RM, Dhaliwal S, Burkhardt MS, Chubb SA, De Ruyck K, Rodrigues M, Mehta PD, Foster JK, Bruce DG, Martins RN. Luteinizing hormone levels are positively correlated with plasma amyloid-beta protein levels in elderly men. Journal of Alzheimer's Disease : Jad. 14: 201-8. PMID 18560131 DOI: 10.3233/Jad-2008-14208  0.541
2008 Rodrigues MA, Verdile G, Foster JK, Hogervorst E, Joesbury K, Dhaliwal S, Corder EH, Laws SM, Hone E, Prince R, Devine A, Mehta P, Beilby J, Atwood CS, Martins RN. Gonadotropins and cognition in older women. Journal of Alzheimer's Disease : Jad. 13: 267-74. PMID 18430994 DOI: 10.3233/Jad-2008-13304  0.627
2008 Foster J, Sohrabi H, Verdile G, Martins R. Research criteria for the diagnosis of Alzheimer's disease: genetic risk factors, blood biomarkers and olfactory dysfunction. International Psychogeriatrics / Ipa. 20: 853-5. PMID 18416874 DOI: 10.1017/S1041610208006807  0.443
2008 Nornes S, Newman M, Verdile G, Wells S, Stoick-Cooper CL, Tucker B, Frederich-Sleptsova I, Martins R, Lardelli M. Interference with splicing of Presenilin transcripts has potent dominant negative effects on Presenilin activity. Human Molecular Genetics. 17: 402-12. PMID 17981814 DOI: 10.1093/Hmg/Ddm317  0.467
2008 Barron AM, Taddei K, DeRuyck K, Croft KD, Mori TA, Verdile G, Martins RN. P1-436: Time- and dose-dependent effects of ovariectomy and human chorionic gonadotropin treatment on beta amyloid and isoprostane levels in the PS1M146V mouse model of Alzheimer's disease Alzheimer's & Dementia. 4: T347-T347. DOI: 10.1016/J.Jalz.2008.05.1018  0.535
2007 Verdile G, Gandy SE, Martins RN. The role of presenilin and its interacting proteins in the biogenesis of Alzheimer's beta amyloid. Neurochemical Research. 32: 609-23. PMID 16944319 DOI: 10.1007/S11064-006-9131-X  0.517
2006 Barron AM, Fuller SJ, Verdile G, Martins RN. Reproductive hormones modulate oxidative stress in Alzheimer's disease. Antioxidants & Redox Signaling. 8: 2047-59. PMID 17034349 DOI: 10.1089/Ars.2006.8.2047  0.545
2006 Barron AM, Verdile G, Martins RN. The role of gonadotropins in Alzheimer's disease: potential neurodegenerative mechanisms. Endocrine. 29: 257-69. PMID 16785601 DOI: 10.1385/Endo:29:2:257  0.597
2006 Martins RN, Balakrishnan K, Verdile G, Bates K, Mehta PD, Beilby J, Nolan D, Galvao D, Gandy SE. P1-167: Plasma Aβ42 correlates positively with increased body fat Alzheimer's & Dementia. 2: S144-S145. DOI: 10.1016/J.Jalz.2006.05.543  0.444
2005 Balakrishnan K, Verdile G, Mehta PD, Beilby J, Nolan D, Galvão DA, Newton R, Gandy SE, Martins RN. Plasma Abeta42 correlates positively with increased body fat in healthy individuals. Journal of Alzheimer's Disease : Jad. 8: 269-82. PMID 16340084 DOI: 10.3233/Jad-2005-8305  0.534
2004 Carter TL, Verdile G, Groth D, Bogush A, Thomas S, Shen P, Fraser PE, Mathews P, Nixon RA, Ehrlich ME, Kwok JB, St George-Hyslop P, Schofield P, Li Y, Yang A, et al. Alzheimer amyloid precursor aspartyl proteinase activity in CHAPSO homogenates of Spodoptera frugiperda cells. Alzheimer Disease and Associated Disorders. 18: 261-3. PMID 15592142  0.445
2004 Verdile G, Gnjec A, Miklossy J, Fonte J, Veurink G, Bates K, Kakulas B, Mehta PD, Milward EA, Tan N, Lareu R, Lim D, Dharmarajan A, Martins RN. Protein markers for Alzheimer disease in the frontal cortex and cerebellum. Neurology. 63: 1385-92. PMID 15505153 DOI: 10.1212/01.Wnl.0000141848.45315.A6  0.533
2004 Verdile G, Fuller S, Atwood CS, Laws SM, Gandy SE, Martins RN. The role of beta amyloid in Alzheimer's disease: still a cause of everything or the only one who got caught? Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 50: 397-409. PMID 15304237 DOI: 10.1016/J.Phrs.2003.12.028  0.68
2004 Verdile G, Groth D, Mathews PM, St George-Hyslop P, Fraser PE, Ramabhadran TV, Kwok JB, Schofield PR, Carter T, Gandy S, Martins RN. Baculoviruses expressing the human familial Alzheimer's disease presenilin 1 mutation lacking exon 9 increase levels of an amyloid beta-like protein in Sf9 cells. Molecular Psychiatry. 9: 594-602. PMID 14993906 DOI: 10.1038/Sj.Mp.4001458  0.403
2004 Bowen RL, Verdile G, Liu T, Parlow AF, Perry G, Smith MA, Martins RN, Atwood CS. Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition. The Journal of Biological Chemistry. 279: 20539-45. PMID 14871891 DOI: 10.1074/Jbc.M311993200  0.687
2004 Liu T, Perry G, Chan HW, Verdile G, Martins RN, Smith MA, Atwood CS. Amyloid-beta-induced toxicity of primary neurons is dependent upon differentiation-associated increases in tau and cyclin-dependent kinase 5 expression. Journal of Neurochemistry. 88: 554-63. PMID 14720205 DOI: 10.1046/J.1471-4159.2003.02196.X  0.645
2004 Verdile G, Groth D, Mathews P, George-Hyslop PS, Fraser P, Ramabhadran T, Kwok J, Schofield P, Carter T, Gandy S, Martins R. P4-265 Baculoviral expressionof the presenilin mutation lacking exon 9 increase levels of an amyloid beta — like protein in SF9insect cells Neurobiology of Aging. 25: S550-S551. DOI: 10.1016/S0197-4580(04)81823-2  0.492
2004 Atwood CS, Liu T, Smith MA, Martins RN, Bowen RL, Verdile G. O2-04-06 17β-Estradiol and luteinizing hormone modulate the expression of luteinizing hormone receptors in neuroblastoma cells Neurobiology of Aging. 25: S40. DOI: 10.1016/S0197-4580(04)80132-5  0.576
2003 Miklossy J, Taddei K, Suva D, Verdile G, Fonte J, Fisher C, Gnjec A, Ghika J, Suard F, Mehta PD, McLean CA, Masters CL, Brooks WS, Martins RN. Two novel presenilin-1 mutations (Y256S and Q222H) are associated with early-onset Alzheimer's disease. Neurobiology of Aging. 24: 655-62. PMID 12885573 DOI: 10.1016/S0197-4580(02)00192-6  0.497
2000 Verdile G, Martins RN, Duthie M, Holmes E, St George-Hyslop PH, Fraser PE. Inhibiting amyloid precursor protein C-terminal cleavage promotes an interaction with presenilin 1. The Journal of Biological Chemistry. 275: 20794-8. PMID 10801777 DOI: 10.1074/Jbc.C000208200  0.51
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