James S. Lowe - Publications

Affiliations: 
Pathology University of Nottingham, Nottingham, England, United Kingdom 
Area:
Dementia, neurodegeneration, movement disorders. Brain tumours. Muscle disease.
Website:
http://www.nottingham.ac.uk/mol/people/james.lowe

64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Ugun-Klusek A, Tatham MH, Elkharaz J, Constantin-Teodosiu D, Lawler K, Mohamed H, Paine SM, Anderson G, John Mayer R, Lowe J, Ellen Billett E, Bedford L. Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway. Cell Death & Disease. 8: e2531. PMID 28055010 DOI: 10.1038/Cddis.2016.443  0.328
2014 Ling H, Ling H, de Silva R, Massey LA, Courtney R, Hondhamuni G, Bajaj N, Lowe J, Holton JL, Lees A, Revesz T. Characteristics of progressive supranuclear palsy presenting with corticobasal syndrome: a cortical variant. Neuropathology and Applied Neurobiology. 40: 149-63. PMID 23432126 DOI: 10.1111/Nan.12037  0.306
2013 Elkharaz J, Ugun-Klusek A, Constantin-Teodosiu D, Lawler K, Mayer RJ, Billett E, Lowe J, Bedford L. Implications for oxidative stress and astrocytes following 26S proteasomal depletion in mouse forebrain neurones. Biochimica Et Biophysica Acta. 1832: 1930-8. PMID 23851049 DOI: 10.1016/J.Bbadis.2013.07.002  0.335
2013 Paine SM, Anderson G, Bedford K, Lawler K, Mayer RJ, Lowe J, Bedford L. Pale body-like inclusion formation and neurodegeneration following depletion of 26S proteasomes in mouse brain neurones are independent of α-synuclein. Plos One. 8: e54711. PMID 23382946 DOI: 10.1371/Journal.Pone.0054711  0.308
2013 Tallantyre E, Wills A, Revesz T, Lowe J. A Novel Tauopathy Presenting With A Motor Neurone Disease Phenotype Journal of Neurology, Neurosurgery, and Psychiatry. 84. DOI: 10.1136/Jnnp-2013-306573.209  0.381
2012 McNaughton D, Knight W, Guerreiro R, Ryan N, Lowe J, Poulter M, Nicholl DJ, Hardy J, Revesz T, Lowe J, Rossor M, Collinge J, Mead S. Duplication of amyloid precursor protein (APP), but not prion protein (PRNP) gene is a significant cause of early onset dementia in a large UK series. Neurobiology of Aging. 33: 426.e13-21. PMID 21193246 DOI: 10.1016/J.Neurobiolaging.2010.10.010  0.334
2011 Paine S, Lowe J, Bedford L, Mayer RJ. Can neurodegeneration be separated from neuropathological hallmarks of chronic idiopathic human neurodegenerative disease? A perspective from modelling! Biochemical Society Transactions. 39: 917-9. PMID 21787323 DOI: 10.1042/Bst0390917  0.355
2011 Bedford L, Lowe J, Dick LR, Mayer RJ, Brownell JE. Ubiquitin-like protein conjugation and the ubiquitin-proteasome system as drug targets. Nature Reviews. Drug Discovery. 10: 29-46. PMID 21151032 DOI: 10.1038/Nrd3321  0.323
2011 Paine SML, Lowe JS. Approach to the post-mortem investigation of neurodegenerative diseases: From diagnosis to research Diagnostic Histopathology. 17: 211-216. DOI: 10.1016/J.Mpdhp.2011.02.004  0.365
2009 Tallantyre EC, Paine SM, Sharp CP, Lowe JS, Gran B. Atypical progressive multifocal leukoencephalopathy associated with an unusual JC polyomavirus mutation. Archives of Neurology. 66: 1021-4. PMID 19667225 DOI: 10.1001/Archneurol.2009.94  0.338
2009 Paine S, Bedford L, Thorpe JR, Mayer RJ, Cavey JR, Bajaj N, Sheppard PW, Lowe J, Layfield R. Immunoreactivity to Lys63-linked polyubiquitin is a feature of neurodegeneration. Neuroscience Letters. 460: 205-8. PMID 19500650 DOI: 10.1016/J.Neulet.2009.05.074  0.388
2009 Bedford L, Paine S, Rezvani N, Mee M, Lowe J, Mayer RJ. The UPS and autophagy in chronic neurodegenerative disease: six of one and half a dozen of the other--or not? Autophagy. 5: 224-7. PMID 19077533 DOI: 10.4161/Auto.5.2.7389  0.367
2008 Bedford L, Hay D, Paine S, Rezvani N, Mee M, Lowe J, Mayer RJ. Is malfunction of the ubiquitin proteasome system the primary cause of alpha-synucleinopathies and other chronic human neurodegenerative disease? Biochimica Et Biophysica Acta. 1782: 683-90. PMID 18976704 DOI: 10.1016/J.Bbadis.2008.10.009  0.382
2008 Bedford L, Hay D, Devoy A, Paine S, Powe DG, Seth R, Gray T, Topham I, Fone K, Rezvani N, Mee M, Soane T, Layfield R, Sheppard PW, Ebendal T, ... ... Lowe J, et al. Depletion of 26S proteasomes in mouse brain neurons causes neurodegeneration and Lewy-like inclusions resembling human pale bodies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 8189-98. PMID 18701681 DOI: 10.1523/Jneurosci.2218-08.2008  0.374
2008 Lowe J. Neuropathology of dementia with Lewy bodies. Handbook of Clinical Neurology. 89: 321-330. PMID 18631757 DOI: 10.1016/S0072-9752(07)01231-6  0.35
2008 Alomar T, Lowe J, Dua H. In vivo confocal microscopy of abnormal cornea: a clinical and pathological correlation Acta Ophthalmologica. 86: 0-0. DOI: 10.1111/J.1755-3768.2008.6231.X  0.318
2007 Cairns NJ, Bigio EH, Mackenzie IR, Neumann M, Lee VM, Hatanpaa KJ, White CL, Schneider JA, Grinberg LT, Halliday G, Duyckaerts C, Lowe JS, Holm IE, Tolnay M, Okamoto K, et al. Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration. Acta Neuropathologica. 114: 5-22. PMID 17579875 DOI: 10.1007/S00401-007-0237-2  0.369
2007 Scott IS, Lowe JS. The ubiquitin-binding protein p62 identifies argyrophilic grain pathology with greater sensitivity than conventional silver stains. Acta Neuropathologica. 113: 417-20. PMID 17146637 DOI: 10.1007/S00401-006-0165-6  0.317
2006 Lowe J, FRCPath D. Establishing a Pathological Diagnosis in Degenerative Dementias Brain Pathology. 8: 403-406. PMID 9546296 DOI: 10.1111/J.1750-3639.1998.Tb00163.X  0.39
2005 Lowe J, Hand N, Mayer RJ. Application of ubiquitin immunohistochemistry to the diagnosis of disease. Methods in Enzymology. 399: 86-119. PMID 16338351 DOI: 10.1016/S0076-6879(05)99007-1  0.393
2005 Layfield R, Lowe J, Bedford L. The ubiquitin-proteasome system and neurodegenerative disorders. Essays in Biochemistry. 41: 157-71. PMID 16250904 DOI: 10.1042/Eb0410157  0.364
2005 McKeith IG, Dickson DW, Lowe J, Emre M, O'Brien JT, Feldman H, Cummings J, Duda JE, Lippa C, Perry EK, Aarsland D, Arai H, Ballard CG, Boeve B, Burn DJ, et al. Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium. Neurology. 65: 1863-72. PMID 16237129 DOI: 10.1212/01.Wnl.0000187889.17253.B1  0.354
2003 Layfield R, Cavey JR, Lowe J. Role of ubiquitin-mediated proteolysis in the pathogenesis of neurodegenerative disorders Ageing Research Reviews. 2: 343-356. PMID 14522239 DOI: 10.1016/S1568-1637(03)00025-4  0.381
2003 Cairns NJ, Perry RH, Jaros E, Burn D, McKeith IG, Lowe JS, Holton J, Rossor MN, Skullerud K, Duyckaerts C, Cruz-Sanchez FF, Lantos PL. Patients with a novel neurofilamentopathy: dementia with neurofilament inclusions. Neuroscience Letters. 341: 177-80. PMID 12697277 DOI: 10.1016/S0304-3940(03)00100-9  0.385
2002 Achim C, Auer R, Bergeron C, Cardozo A, Deprez M, de Vos R, Duyckaerts C, Egensperger R, Esiri M, Frosch MP, Giannini C, Goebel HH, Graeber MB, Graham DI, Gray F, ... ... Lowe J, et al. Global democratic consensus on neuropathological disease criteria. The Lancet. Neurology. 1: 340. PMID 12849392 DOI: 10.1016/S1474-4422(02)00156-4  0.321
2001 Layfield R, Alban A, Mayer RJ, Lowe J. The ubiquitin protein catabolic disorders. Neuropathology and Applied Neurobiology. 27: 171-9. PMID 11489136 DOI: 10.1046/J.1365-2990.2001.00335.X  0.363
2000 Lowe J. Evidence of a CJD epidemic may still be missed. Bmj. 320: 1011-1011. PMID 10753167 DOI: 10.1136/Bmj.320.7240.1011  0.301
2000 Fergusson J, Landon M, Lowe J, Ward L, van Leeuwen FW, Mayer RJ. Neurofibrillary tangles in progressive supranuclear palsy brains exhibit immunoreactivity to frameshift mutant ubiquitin-B protein. Neuroscience Letters. 279: 69-72. PMID 10674623 DOI: 10.1016/S0304-3940(99)00917-9  0.365
1998 Arnold J, Dawson S, Fergusson J, Lowe J, Landon M, Mayer RJ. Ubiquitin and its role in neurodegeneration. Progress in Brain Research. 117: 23-34. PMID 9932397 DOI: 10.1016/S0079-6123(08)64004-2  0.321
1998 Hughes RGM, Gibbin KP, Lowe J. Vocal fold abductor paralysis as a solitary and fatal manifestation of multiple system atrophy. Journal of Laryngology and Otology. 112: 177-178. PMID 9578881 DOI: 10.1017/S0022215100140241  0.305
1997 Lowe J, Dickson D. Pathological diagnostic criteria for dementia associated with cortical Lewy bodies: review and proposal for a descriptive approach. Journal of Neural Transmission-Supplement. 51: 111-120. PMID 9470132 DOI: 10.1007/978-3-7091-6846-2_9  0.356
1997 Bell JE, Gentleman SM, Ironside JW, McCardle L, Lantos PL, Doey L, Lowe J, Fergusson J, Luthert P, McQuaid S, Allen IV. Prion protein immunocytochemistry – UK five centre consensus report Neuropathology and Applied Neurobiology. 23: 26-35. DOI: 10.1111/J.1365-2990.1997.Tb01182.X  0.321
1996 Jackson M, Lennox G, Lowe J. Motor neurone disease-inclusion dementia. Neurodegeneration. 5: 339-350. PMID 9117546 DOI: 10.1006/Neur.1996.0046  0.351
1996 Fergusson J, Landon M, Lowe J, Dawson SP, Layfield R, Hanger DP, Mayer RJ. Pathological lesions of Alzheimer's disease and dementia with Lewy bodies brains exhibit immunoreactivity to an ATPase that is a regulatory subunit of the 26S proteasome. Neuroscience Letters. 219: 167-70. PMID 8971806 DOI: 10.1016/S0304-3940(96)13192-X  0.345
1996 McKeith IG, Galasko D, Kosaka K, Perry EK, Dickson DW, Hansen LA, Salmon DP, Lowe J, Mirra SS, Byrne EJ, Lennox G, Quinn NP, Edwardson JA, Ince PG, Bergeron C, et al. Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop. Neurology. 47: 1113-24. PMID 8909416 DOI: 10.1212/Wnl.47.5.1113  0.378
1996 Mayer RJ, Tipler C, Arnold J, Laszlo L, Al-Khedhairy A, Lowe J, Landon M. Endosome-lysosomes, ubiquitin and neurodegeneration. Advances in Experimental Medicine and Biology. 389: 261-9. PMID 8861020 DOI: 10.1007/978-1-4613-0335-0_33  0.374
1996 Jackson M, Lowe J. The new neuropathology of degenerative frontotemporal dementias. Acta Neuropathologica. 91: 127-134. PMID 8787144 DOI: 10.1007/S004010050403  0.382
1996 Layfield R, Fergusson J, Aitken A, Lowe J, Landon M, Mayer RJ. Neurofibrillary tangles of Alzheimer's disease brains contain 14-3-3 proteins. Neuroscience Letters. 209: 57-60. PMID 8734909 DOI: 10.1016/0304-3940(96)12598-2  0.366
1995 Williams TL, Shaw PJ, Lowe J, Bates D, Ince PG. Parkinsonism in motor neuron disease: case report and literature review. Acta Neuropathologica. 89: 275-83. PMID 7754748 DOI: 10.1007/Bf00309344  0.354
1995 Cooper PN, Jackson M, Lennox G, Lowe J, Mann DM. Tau, ubiquitin, and alpha B-crystallin immunohistochemistry define the principal causes of degenerative frontotemporal dementia. Archives of Neurology. 52: 1011-5. PMID 7575218 DOI: 10.1001/Archneur.1995.00540340103019  0.383
1994 Lowe J. New pathological findings in amyotrophic lateral sclerosis Journal of the Neurological Sciences. 124: 38-51. PMID 7807140 DOI: 10.1016/0022-510X(94)90175-9  0.317
1993 Hopkinson ND, Hunt C, Powell RJ, Lowe J. Inclusion body myositis: an underdiagnosed condition? Annals of the Rheumatic Diseases. 52: 147-151. PMID 8383483 DOI: 10.1136/Ard.52.2.147  0.31
1993 Lowe J, Mayer RJ, Landon M. Ubiquitin in neurodegenerative diseases. Brain Pathology (Zurich, Switzerland). 3: 55-65. PMID 8269084 DOI: 10.1111/J.1750-3639.1993.Tb00726.X  0.363
1992 Laszlo L, Lowe J, Self T, Kenward N, Landon M, McBride T, Farquhar C, McConnell I, Brown J, Hope J. Lysosomes as key organelles in the pathogenesis of prion encephalopathies. The Journal of Pathology. 166: 333-41. PMID 1355530 DOI: 10.1002/Path.1711660404  0.335
1992 Mayer RJ, Laszlo L, Landon M, Hope J, Lowe J. Ubiquitin, lysosomes, and neurodegenerative diseases. Annals of the New York Academy of Sciences. 674: 149-60. PMID 1337689 DOI: 10.1111/J.1749-6632.1992.Tb27484.X  0.343
1992 Lowe J, Fergusson J, Kenward N, Laszlo L, Landon M, Farquhar C, Brown J, Hope J, Mayer RJ. Immunoreactivity to ubiquitin-protein conjugates is present early in the disease process in the brains of scrapie-infected mice. The Journal of Pathology. 168: 169-77. PMID 1334140 DOI: 10.1002/Path.1711680204  0.34
1992 Lowe J, McDermott H, Pike I, Spendlove I, Landon M, Mayer RJ. alpha B crystallin expression in non-lenticular tissues and selective presence in ubiquitinated inclusion bodies in human disease. The Journal of Pathology. 166: 61-8. PMID 1311375 DOI: 10.1002/Path.1711660110  0.319
1991 Mayer RJ, Lowe J, Landon M. Ubiquitin and the molecular pathology of chronic degenerative diseases. The Journal of Pathology. 163: 279-81. PMID 1851826 DOI: 10.1002/Path.1711630402  0.361
1991 Mayer RJ, Arnold J, László L, Landon M, Lowe J. Ubiquitin in health and disease. Biochimica Et Biophysica Acta. 1089: 141-57. PMID 1647208 DOI: 10.1016/0167-4781(91)90002-4  0.331
1990 Lowe J, Mayer RJ. Ubiquitin, cell stress and diseases of the nervous system. Neuropathology and Applied Neurobiology. 16: 281-291. PMID 2172853 DOI: 10.1111/J.1365-2990.1990.Tb01263.X  0.357
1990 Lowe J, McDermott H, Landon M, Mayer RJ, Wilkinson KD. Ubiquitin carboxyl-terminal hydrolase (PGP 9.5) is selectively present in ubiquitinated inclusion bodies characteristic of human neurodegenerative diseases. The Journal of Pathology. 161: 153-60. PMID 2166150 DOI: 10.1002/Path.1711610210  0.395
1990 Lowe J, McDermott H, Kenward N, Landon M, Mayer RJ, Bruce M, McBride P, Somerville RA, Hope J. Ubiquitin conjugate immunoreactivity in the brains of scrapie infected mice. The Journal of Pathology. 162: 61-6. PMID 1977900 DOI: 10.1002/Path.1711620112  0.38
1990 Barbosa MD, Balsitis M, Jaspan T, Lowe J. Intraventricular neurocytoma: a clinical and pathological study of three cases and review of the literature. Neurosurgery. 26: 1045-1054. DOI: 10.1227/00006123-199006000-00022  0.318
1989 Lennox G, Lowe JS, Godwin-Austen RB, Landon M, Mayer RJ. Diffuse Lewy body disease: an important differential diagnosis in dementia with extrapyramidal features. Progress in Clinical and Biological Research. 317: 121-30. PMID 2602409 DOI: 10.1097/00002093-198802030-00016  0.334
1989 Lennox G, Lowe J, Landon M, Byrne EJ, Mayer RJ, Godwin-Austen RB. Diffuse Lewy body disease: correlative neuropathology using anti-ubiquitin immunocytochemistry. Journal of Neurology, Neurosurgery, and Psychiatry. 52: 1236-47. PMID 2556498 DOI: 10.1136/Jnnp.52.11.1236  0.36
1989 Byrne EJ, Lennox G, Lowe J, Godwin-Austen RB. Diffuse Lewy body disease: clinical features in 15 cases. Journal of Neurology, Neurosurgery, and Psychiatry. 52: 709-717. PMID 2545827 DOI: 10.1136/Jnnp.52.6.709  0.365
1989 Lowe J, Morrell K, Lennox G, Landon M, Mayer RJ. Rosenthal fibres are based on the ubiquitination of glial filaments. Neuropathology and Applied Neurobiology. 15: 45-53. PMID 2542826 DOI: 10.1111/J.1365-2990.1989.Tb01148.X  0.301
1989 Lennox G, Lowe J, Morrell K, Landon M, Mayer RJ. Anti-ubiquitin immunocytochemistry is more sensitive than conventional techniques in the detection of diffuse Lewy body disease. Journal of Neurology, Neurosurgery, and Psychiatry. 52: 67-71. PMID 2540286 DOI: 10.1136/Jnnp.52.1.67  0.316
1989 Lowe J, Aldridge F, Lennox G, Doherty F, Jefferson D, Landon M, Mayer RJ. Inclusion bodies in motor cortex and brainstem of patients with motor neurone disease are detected by immunocytochemical localisation of ubiquitin. Neuroscience Letters. 105: 7-13. PMID 2484732 DOI: 10.1016/0304-3940(89)90003-7  0.31
1988 Lennox G, Lowe J, Morrell K, Landon M, Mayer RJ. Ubiquitin is a component of neurofibrillary tangles in a variety of neurodegenerative diseases. Neuroscience Letters. 94: 211-7. PMID 2853854 DOI: 10.1016/0304-3940(88)90297-2  0.388
1988 Lowe J, Lennox G, Jefferson D, Morrell K, McQuire D, Gray T, Landon M, Doherty FJ, Mayer RJ. A filamentous inclusion body within anterior horn neurones in motor neurone disease defined by immunocytochemical localisation of ubiquitin. Neuroscience Letters. 94: 203-10. PMID 2853853 DOI: 10.1016/0304-3940(88)90296-0  0.355
1988 Lowe J, Blanchard A, Morrell K, Lennox G, Reynolds L, Billett M, Landon M, Mayer RJ. Ubiquitin is a common factor in intermediate filament inclusion bodies of diverse type in man, including those of Parkinson's disease, Pick's disease, and Alzheimer's disease, as well as Rosenthal fibres in cerebellar astrocytomas, cytoplasmic bodies in muscle, and mallory bodies in alcoholic liver disease. The Journal of Pathology. 155: 9-15. PMID 2837558 DOI: 10.1002/Path.1711550105  0.357
1987 Byrne EJ, Lowe J, Godwin-Austen RB, Arie T, Jones R. Dementia And Parkinson'S Disease Associated With Diffuse Cortical Lewy Bodies The Lancet. 329: 501. PMID 2881052 DOI: 10.1016/S0140-6736(87)92104-0  0.33
1986 Allsop D, Landon M, Kidd M, Lowe JS, Reynolds GP, Gardner A. Monoclonal antibodies raised against a subsequence of senile plaque core protein react with plaque cores, plaque periphery and cerebrovascular amyloid in Alzheimer's disease. Neuroscience Letters. 68: 252-6. PMID 3748453 DOI: 10.1016/0304-3940(86)90152-7  0.323
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