Sheetal Gandotra, Ph.D. - Publications

Affiliations: 
2008 Weill Cornell Medical College, New York, NY, United States 
Area:
Microbiology Biology, Immunology

23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Shankaran D, Singh A, Dawa S, Arumugam P, Gandotra S, Rao V. The antidepressant sertraline provides a novel host directed therapy module for augmenting TB therapy. Elife. 12. PMID 36629405 DOI: 10.7554/eLife.64834  0.358
2022 Shankaran D, Arumugam P, Vasanthakumar RP, Singh A, Bothra A, Gandotra S, Rao V. Modern Clinical Strains Leverage Type I IFN Pathway for a Proinflammatory Response in the Host. Journal of Immunology (Baltimore, Md. : 1950). 209: 1736-1745. PMID 36150728 DOI: 10.4049/jimmunol.2101029  0.337
2021 Dawa S, Menon D, Arumugam P, Bhaskar AK, Mondal M, Rao V, Gandotra S. Inhibition of Granuloma Triglyceride Synthesis Imparts Control of Through Curtailed Inflammatory Responses. Frontiers in Immunology. 12: 722735. PMID 34603294 DOI: 10.3389/fimmu.2021.722735  0.43
2019 De Majumdar S, Sikri K, Ghosh P, Jaisinghani N, Nandi M, Gandotra S, Mande S, Tyagi JS. Genome analysis identifies a spontaneous nonsense mutation in ppsD leading to attenuation of virulence in laboratory-manipulated Mycobacterium tuberculosis. Bmc Genomics. 20: 129. PMID 30755157 DOI: 10.1186/S12864-019-5482-Y  0.72
2019 Menon D, Singh K, Pinto SM, Nandy A, Jaisinghani N, Kutum R, Dash D, Prasad TK, Gandotra S. Quantitative lipid droplet proteomics reveals Mycobacterium tuberculosis induced alterations in macrophage response to infection. Acs Infectious Diseases. PMID 30663302 DOI: 10.1021/Acsinfecdis.8B00301  0.749
2019 Misra R, Menon D, Arora G, Virmani R, Gaur M, Naz S, Jaisinghani N, Bhaduri A, Bothra A, Maji A, Singhal A, Karwal P, Hentschker C, Becher D, Rao V, ... ... Gandotra S, et al. Tuning the alternative sigma factor SigF through the multidomain regulator Rv1364c and osmosensory kinase, protein kinase D. Journal of Bacteriology. PMID 30642988 DOI: 10.1128/Jb.00725-18  0.728
2018 Arumugam P, Shankaran D, Bothra A, Gandotra S, Rao V. The MmpS6-MmpL6 operon is an oxidative stress response system providing selective advantage to Mycobacterium tuberculosis in stress. The Journal of Infectious Diseases. PMID 30203030 DOI: 10.1093/Infdis/Jiy526  0.402
2018 Jaisinghani N, Dawa S, Singh K, Nandy A, Menon D, Bhandari PD, Khare G, Tyagi A, Gandotra S. Necrosis Driven Triglyceride Synthesis Primes Macrophages for Inflammation During Infection. Frontiers in Immunology. 9: 1490. PMID 30018616 DOI: 10.3389/Fimmu.2018.01490  0.749
2018 Pinto SM, Verma R, Advani J, Chatterjee O, Patil AH, Kapoor S, Subbannayya Y, Raja R, Gandotra S, Prasad TSK. Integrated Multi-Omic Analysis of H37Ra Redefines Virulence Attributes. Frontiers in Microbiology. 9: 1314. PMID 29971057 DOI: 10.3389/Fmicb.2018.01314  0.371
2018 Bothra A, Arumugam P, Panchal V, Menon D, Srivastava S, Shankaran D, Nandy A, Jaisinghani N, Singh A, Gokhale RS, Gandotra S, Rao V. Phospholipid homeostasis, membrane tenacity and survival of Mtb in lipid rich conditions is determined by MmpL11 function. Scientific Reports. 8: 8317. PMID 29844505 DOI: 10.1038/S41598-018-26710-Z  0.745
2018 Nandy A, Mondal AK, Pandey R, Arumugam P, Dawa S, Jaisinghani N, Rao V, Dash D, Gandotra S. Adipocyte model of My infection reveals differential iron availability to bacilli in the lipid rich caseous environment. Infection and Immunity. PMID 29632245 DOI: 10.1128/Iai.00041-18  0.742
2017 Verma R, Pinto SM, Patil AH, Advani J, Subba P, Kumar M, Sharma J, Dey G, Ravikumar R, Buggi S, Satishchandra P, Sharma K, Suar M, Tripathy SP, Chauhan DS, ... ... Gandotra S, et al. Quantitative proteomic and phosphoproteomic analysis of H37Ra and H37Rv strains of Mycobacterium tuberculosis. Journal of Proteome Research. PMID 28241730 DOI: 10.1021/Acs.Jproteome.6B00983  0.478
2015 Nagarajan SN, Upadhyay S, Chawla Y, Khan S, Naz S, Subramanian J, Gandotra S, Nandicoori VK. Protein kinase A (PknA) of Mycobacterium tuberculosis is independently activated and is critical for growth in vitro and survival of the pathogen in the host. The Journal of Biological Chemistry. 290: 9626-45. PMID 25713147 DOI: 10.1074/Jbc.M114.611822  0.358
2015 Kozusko K, Tsang VH, Bottomley W, Cho YH, Gandotra S, Mimmack M, Lim K, Isaac I, Patel S, Saudek V, O'Rahilly S, Srinivasan S, Greenfield JR, Barroso I, Campbell LV, et al. Clinical and molecular characterization of a novel PLIN1 frameshift mutation identified in patients with familial partial lipodystrophy. Diabetes. 64: 299-310. PMID 25114292 DOI: 10.2337/db14-0104  0.469
2015 Singh LK, Dhasmana N, Sajid A, Kumar P, Bhaduri A, Bharadwaj M, Gandotra S, Kalia VC, Das TK, Goel AK, Pomerantsev AP, Misra R, Gerth U, Leppla SH, Singh Y. clpC operon regulates cell architecture and sporulation in Bacillus anthracis. Environmental Microbiology. 17: 855-65. PMID 24947607 DOI: 10.1111/1462-2920.12548  0.354
2013 Chauhan P, Reddy PV, Singh R, Jaisinghani N, Gandotra S, Tyagi AK. Secretory phosphatases deficient mutant of Mycobacterium tuberculosis imparts protection at the primary site of infection in guinea pigs. Plos One. 8: e77930. PMID 24205032 DOI: 10.1371/Journal.Pone.0077930  0.727
2011 Gandotra S, Lim K, Girousse A, Saudek V, O'Rahilly S, Savage DB. Human frame shift mutations affecting the carboxyl terminus of perilipin increase lipolysis by failing to sequester the adipose triglyceride lipase (ATGL) coactivator AB-hydrolase-containing 5 (ABHD5). The Journal of Biological Chemistry. 286: 34998-5006. PMID 21757733 DOI: 10.1074/Jbc.M111.278853  0.455
2011 Gandotra S, Le Dour C, Bottomley W, Cervera P, Giral P, Reznik Y, Charpentier G, Auclair M, Delépine M, Barroso I, Semple RK, Lathrop M, Lascols O, Capeau J, O'Rahilly S, et al. Perilipin deficiency and autosomal dominant partial lipodystrophy. The New England Journal of Medicine. 364: 740-8. PMID 21345103 DOI: 10.1056/Nejmoa1007487  0.496
2010 Gandotra S, Lebron MB, Ehrt S. The Mycobacterium tuberculosis proteasome active site threonine is essential for persistence yet dispensable for replication and resistance to nitric oxide. Plos Pathogens. 6: e1001040. PMID 20711362 DOI: 10.1371/Journal.Ppat.1001040  0.628
2007 Gandotra S, Schnappinger D, Monteleone M, Hillen W, Ehrt S. In vivo gene silencing identifies the Mycobacterium tuberculosis proteasome as essential for the bacteria to persist in mice. Nature Medicine. 13: 1515-20. PMID 18059281 DOI: 10.1038/Nm1683  0.63
2007 Gandotra S, Jang S, Murray PJ, Salgame P, Ehrt S. Nucleotide-binding oligomerization domain protein 2-deficient mice control infection with Mycobacterium tuberculosis. Infection and Immunity. 75: 5127-34. PMID 17709422 DOI: 10.1128/Iai.00458-07  0.637
2005 Shi S, Blumenthal A, Hickey CM, Gandotra S, Levy D, Ehrt S. Expression of many immunologically important genes in Mycobacterium tuberculosis-infected macrophages is independent of both TLR2 and TLR4 but dependent on IFN-alphabeta receptor and STAT1. Journal of Immunology (Baltimore, Md. : 1950). 175: 3318-28. PMID 16116224 DOI: 10.4049/Jimmunol.175.5.3318  0.603
2005 Hisert KB, MacCoss M, Shiloh MU, Darwin KH, Singh S, Jones RA, Ehrt S, Zhang Z, Gaffney BL, Gandotra S, Holden DW, Murray D, Nathan C. A glutamate-alanine-leucine (EAL) domain protein of Salmonella controls bacterial survival in mice, antioxidant defence and killing of macrophages: role of cyclic diGMP. Molecular Microbiology. 56: 1234-45. PMID 15882417 DOI: 10.1111/J.1365-2958.2005.04632.X  0.588
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