Gregory Paul Winter, Ph.D. - Publications

Division of Protein and Nucleic Acid Chemistry-Biotechnology MRC Laboratory of Molecular Biology, Cambridge, England, United Kingdom 
therapeutic monoclonal antibodies humanise antibodies, using phage display, antibodies for therapeutic uses

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Year Citation  Score
2015 Heinis C, Winter G. Encoded libraries of chemically modified peptides. Current Opinion in Chemical Biology. 26: 89-98. PMID 25768886 DOI: 10.1016/j.cbpa.2015.02.008  1
2015 Luzi S, Kondo Y, Bernard E, Stadler LK, Vaysburd M, Winter G, Holliger P. Subunit disassembly and inhibition of TNFα by a semi-synthetic bicyclic peptide. Protein Engineering, Design & Selection : Peds. 28: 45-52. PMID 25614525 DOI: 10.1093/protein/gzu055  1
2014 Huter P, Winter G, Schwab M, Renhart P, Oberfrank S, Grün F, Stauder B. Comparison of microstructural crack paths between hypo-eutectic Al-Si-Cu and Al-Si-Mg cast alloys in high plasticity regimes under rotating bending Materials Science and Engineering A. 618: 578-585. DOI: 10.1016/j.msea.2014.08.062  0.04
2013 Härtl E, Winter G, Besheer A. Influence of hydroxypropyl-Beta-cyclodextrin on the stability of dilute and highly concentrated immunoglobulin g formulations. Journal of Pharmaceutical Sciences. 102: 4121-31. PMID 24105716 DOI: 10.1002/jps.23729  0.12
2013 Zölls S, Gregoritza M, Tantipolphan R, Wiggenhorn M, Winter G, Friess W, Hawe A. How subvisible particles become invisible-relevance of the refractive index for protein particle analysis. Journal of Pharmaceutical Sciences. 102: 1434-46. PMID 23463514 DOI: 10.1002/jps.23479  0.01
2012 Baeriswyl V, Rapley H, Pollaro L, Stace C, Teufel D, Walker E, Chen S, Winter G, Tite J, Heinis C. Bicyclic peptides with optimized ring size inhibit human plasma kallikrein and its orthologues while sparing paralogous proteases. Chemmedchem. 7: 1173-6. PMID 22492508 DOI: 10.1002/cmdc.201200071  1
2012 Angelini A, Cendron L, Chen S, Touati J, Winter G, Zanotti G, Heinis C. Bicyclic peptide inhibitor reveals large contact interface with a protease target. Acs Chemical Biology. 7: 817-21. PMID 22304751 DOI: 10.1021/cb200478t  1
2011 Winter G. Greg Winter. Nature Biotechnology. 29: 190. PMID 21390009 DOI: 10.1038/nbt.1815  1
2010 Holliday R, Sleigh M, Winter G. In memoriam Geoffrey W. Grigg (1926-2008). Genetics. 185: 1-3. PMID 20516290 DOI: 10.1534/genetics.110.116624  1
2009 Heinis C, Rutherford T, Freund S, Winter G. Phage-encoded combinatorial chemical libraries based on bicyclic peptides. Nature Chemical Biology. 5: 502-7. PMID 19483697 DOI: 10.1038/nchembio.184  1
2009 Winter G. Advice on mile-high treatment (23 February) Australian Doctor. 27.  1
2008 Famm K, Hansen L, Christ D, Winter G. Thermodynamically stable aggregation-resistant antibody domains through directed evolution. Journal of Molecular Biology. 376: 926-31. PMID 18199455 DOI: 10.1016/j.jmb.2007.10.075  1
2008 Fersht AR, Winter GP. Redesigning Enzymes by Site-Directed Mutagenesis Enzymes in Organic Synthesis. 204-218. DOI: 10.1002/9780470720929.ch14  1
2007 Christ D, Famm K, Winter G. Repertoires of aggregation-resistant human antibody domains. Protein Engineering, Design & Selection : Peds. 20: 413-6. PMID 17720749 DOI: 10.1093/protein/gzm037  1
2007 James LC, Jones PC, McCoy A, Tennent GA, Pepys MB, Famm K, Winter G. Beta-edge interactions in a pentadecameric human antibody V kappa domain. Journal of Molecular Biology. 367: 603-8. PMID 17292396 DOI: 10.1016/j.jmb.2006.10.093  1
2006 Riechmann L, Winter G. Early protein evolution: building domains from ligand-binding polypeptide segments. Journal of Molecular Biology. 363: 460-8. PMID 16978646 DOI: 10.1016/j.jmb.2006.08.031  1
2006 Christ D, Famm K, Winter G. Tapping diversity lost in transformations--in vitro amplification of ligation reactions. Nucleic Acids Research. 34: e108. PMID 16945952 DOI: 10.1093/nar/gkl605  1
2006 Famm K, Winter G. Engineering aggregation-resistant proteins by directed evolution. Protein Engineering, Design & Selection : Peds. 19: 479-81. PMID 16920746 DOI: 10.1093/protein/gzl032  1
2006 Paus D, Winter G. Mapping epitopes and antigenicity by site-directed masking. Proceedings of the National Academy of Sciences of the United States of America. 103: 9172-7. PMID 16754878 DOI: 10.1073/pnas.0600263103  1
2006 Christ D, Winter G. Identification of protein domains by shotgun proteolysis. Journal of Molecular Biology. 358: 364-71. PMID 16516923 DOI: 10.1016/j.jmb.2006.01.057  1
2006 Griffin H, Elston R, Jackson D, Ansell K, Coleman M, Winter G, Doorbar J. Inhibition of papillomavirus protein function in cervical cancer cells by intrabody targeting. Journal of Molecular Biology. 355: 360-78. PMID 16324714 DOI: 10.1016/j.jmb.2005.10.077  1
2005 Wang PL, Lo BK, Winter G. Generating molecular diversity by homologous recombination in Escherichia coli. Protein Engineering, Design & Selection : Peds. 18: 397-404. PMID 15983006 DOI: 10.1093/protein/gzi042  1
2005 Riechmann L, Lavenir I, de Bono S, Winter G. Folding and stability of a primitive protein. Journal of Molecular Biology. 348: 1261-72. PMID 15854659 DOI: 10.1016/j.jmb.2005.03.029  1
2005 de Bono S, Riechmann L, Girard E, Williams RL, Winter G. A segment of cold shock protein directs the folding of a combinatorial protein. Proceedings of the National Academy of Sciences of the United States of America. 102: 1396-401. PMID 15671167 DOI: 10.1073/pnas.0407298102  1
2004 Jespers L, Bonnert TP, Winter G. Selection of optical biosensors from chemisynthetic antibody libraries. Protein Engineering, Design & Selection : Peds. 17: 709-13. PMID 15537669 DOI: 10.1093/protein/gzh083  1
2004 Jespers L, Schon O, Famm K, Winter G. Aggregation-resistant domain antibodies selected on phage by heat denaturation. Nature Biotechnology. 22: 1161-5. PMID 15300256 DOI: 10.1038/nbt1000  1
2004 Jespers L, Schon O, James LC, Veprintsev D, Winter G. Crystal structure of HEL4, a soluble, refoldable human V(H) single domain with a germ-line scaffold. Journal of Molecular Biology. 337: 893-903. PMID 15033359 DOI: 10.1016/j.jmb.2004.02.013  1
2004 Abelian A, Burling K, Easterbrook P, Winter G. Hyperimmunoglobulinemia and rate of HIV type 1 infection progression. Aids Research and Human Retroviruses. 20: 127-8. PMID 15000704 DOI: 10.1089/088922204322749576  1
2004 Fischer N, Riechmann L, Winter G. A native-like artificial protein from antisense DNA. Protein Engineering, Design & Selection : Peds. 17: 13-20. PMID 14985533 DOI: 10.1093/protein/gzh002  1
2004 Fersht A, Daggett V, Winter G. Welcome to Protein Engineering, Design and Selection Protein Engineering, Design and Selection. 17: 1. DOI: 10.1093/protein/gzh008  1
2004 Ueda H, Kristensen P, Winter G. Stabilization of antibody VH-domains by proteolytic selection Journal of Molecular Catalysis B: Enzymatic. 28: 173-179. DOI: 10.1016/j.molcatb.2003.12.018  1
2003 Christ D, Winter G. Identification of functional similarities between proteins using directed evolution. Proceedings of the National Academy of Sciences of the United States of America. 100: 13202-6. PMID 14573700 DOI: 10.1073/pnas.2134365100  1
2002 Leslie AG, Powell HR, Winter G, Svensson O, Spruce D, McSweeney S, Love D, Kinder S, Duke E, Nave C. Automation of the collection and processing of X-ray diffraction data -- a generic approach. Acta Crystallographica. Section D, Biological Crystallography. 58: 1924-8. PMID 12393923 DOI: 10.1107/S0907444902016864  1
2002 Sanz L, Kristensen P, Blanco B, Facteau S, Russell SJ, Winter G, Alvarez-Vallina L. Single-chain antibody-based gene therapy: inhibition of tumor growth by in situ production of phage-derived human antibody fragments blocking functionally active sites of cell-associated matrices. Gene Therapy. 9: 1049-53. PMID 12101437 DOI: 10.1038/  1
2002 Goletz S, Christensen PA, Kristensen P, Blohm D, Tomlinson I, Winter G, Karsten U. Selection of large diversities of antiidiotypic antibody fragments by phage display. Journal of Molecular Biology. 315: 1087-97. PMID 11827478 DOI: 10.1006/jmbi.2001.5314  1
2001 Vaisbourd M, Ignatovich O, Dremucheva A, Karpas A, Winter G. Molecular characterization of human monoclonal antibodies derived from fusions of tonsil lymphocytes with a human myeloma cell line. Hybridoma and Hybridomics. 20: 287-92. PMID 11839246 DOI: 10.1089/15368590152740680  1
2001 Wang PL, Sait F, Winter G. The 'wildtype' conformation of p53: epitope mapping using hybrid proteins. Oncogene. 20: 2318-24. PMID 11402327 DOI: 10.1038/sj.onc.1204316  1
2001 Jestin JL, Volioti G, Winter G. Improving the display of proteins on filamentous phage. Research in Microbiology. 152: 187-91. PMID 11316373 DOI: 10.1016/S0923-2508(01)01191-3  1
2000 Riechmann L, Winter G. Novel folded protein domains generated by combinatorial shuffling of polypeptide segments. Proceedings of the National Academy of Sciences of the United States of America. 97: 10068-73. PMID 10954734 DOI: 10.1073/pnas.170145497  1
2000 Ueda H, Kawahara M, Aburatani T, Tsumoto K, Todokoro K, Suzuki E, Nishimura H, Schueler PA, Winter G, Mahoney WC, Kumagai I, Nagamune T. Cell-growth control by monomeric antigen: the cell surface expression of lysozyme-specific Ig V-domains fused to truncated Epo receptor. Journal of Immunological Methods. 241: 159-70. PMID 10915858 DOI: 10.1016/S0022-1759(00)00202-7  1
2000 de Wildt RM, Tomlinson IM, van Venrooij WJ, Winter G, Hoet RM. Comparable heavy and light chain pairings in normal and systemic lupus erythematosus IgG(+) B cells. European Journal of Immunology. 30: 254-61. PMID 10602048 DOI: 10.1002/1521-4141(200001)30:1<254::AID-IMMU254>3.0.CO;2-X  1
1999 Jestin JL, Kristensen P, Winter G. A method for the selection of catalytic activity using phage display and proximity coupling. Angewandte Chemie (International Ed. in English). 38: 1124-7. PMID 25138517 DOI: 10.1002/(SICI)1521-3773(19990419)38:8<1124::AID-ANIE1124>3.0.CO;2-W  1
1999 de Wildt RM, van Venrooij WJ, Winter G, Hoet RM, Tomlinson IM. Somatic insertions and deletions shape the human antibody repertoire. Journal of Molecular Biology. 294: 701-10. PMID 10610790 DOI: 10.1006/jmbi.1999.3289  1
1999 Ignatovich O, Tomlinson IM, Popov AV, Brüggemann M, Winter G. Dominance of intrinsic genetic factors in shaping the human immunoglobulin Vlambda repertoire. Journal of Molecular Biology. 294: 457-65. PMID 10610771 DOI: 10.1006/jmbi.1999.3243  1
1999 Chatellier J, Hartley O, Griffiths AD, Fersht AR, Winter G, Riechmann L. Interdomain interactions within the gene 3 protein of filamentous phage. Febs Letters. 463: 371-4. PMID 10606756 DOI: 10.1016/S0014-5793(99)01658-0  1
1999 Holliger P, Manzke O, Span M, Hawkins R, Fleischmann B, Qinghua L, Wolf J, Diehl V, Cochet O, Winter G, Bohlen H. Carcinoembryonic antigen (CEA)-specific T-cell activation in colon carcinoma induced by anti-CD3 x anti-CEA bispecific diabodies and B7 x anti-CEA bispecific fusion proteins. Cancer Research. 59: 2909-16. PMID 10383154  1
1999 Carnemolla B, Castellani P, Ponassi M, Borsi L, Urbini S, Nicolo G, Dorcaratto A, Viale G, Winter G, Neri D, Zardi L. Identification of a glioblastoma-associated tenascin-C isoform by a high affinity recombinant antibody. The American Journal of Pathology. 154: 1345-52. PMID 10329587 DOI: 10.1016/S0002-9440(10)65388-6  1
1999 Demartis S, Huber A, Viti F, Lozzi L, Giovannoni L, Neri P, Winter G, Neri D. A strategy for the isolation of catalytic activities from repertoires of enzymes displayed on phage. Journal of Molecular Biology. 286: 617-33. PMID 9973575 DOI: 10.1006/jmbi.1998.2476  1
1999 Kirkham PM, Neri D, Winter G. Towards the design of an antibody that recognises a given protein epitope. Journal of Molecular Biology. 285: 909-15. PMID 9887259 DOI: 10.1006/jmbi.1998.2336  1
1999 de Wildt RM, Hoet RM, van Venrooij WJ, Tomlinson IM, Winter G. Analysis of heavy and light chain pairings indicates that receptor editing shapes the human antibody repertoire. Journal of Molecular Biology. 285: 895-901. PMID 9887257 DOI: 10.1006/jmbi.1998.2396  1
1998 Winter G. Making antibody and peptide ligands by repertoire selection technologies. Journal of Molecular Recognition : Jmr. 11: 126-7. PMID 10076824 DOI: 10.1002/(SICI)1099-1352(199812)11:1/6<126::AID-JMR407>3.0.CO;2-H  1
1998 Kristensen P, Winter G. Proteolytic selection for protein folding using filamentous bacteriophages. Folding & Design. 3: 321-8. PMID 9806934 DOI: 10.1016/S1359-0278(98)00044-3  1
1998 Winter G. Synthetic human antibodies and a strategy for protein engineering. Febs Letters. 430: 92-4. PMID 9678601 DOI: 10.1016/S0014-5793(98)00628-0  1
1998 Martineau P, Jones P, Winter G. Expression of an antibody fragment at high levels in the bacterial cytoplasm. Journal of Molecular Biology. 280: 117-27. PMID 9653035 DOI: 10.1006/jmbi.1998.1840  1
1998 Smith GP, Patel SU, Windass JD, Thornton JM, Winter G, Griffiths AD. Small binding proteins selected from a combinatorial repertoire of knottins displayed on phage. Journal of Molecular Biology. 277: 317-32. PMID 9514763 DOI: 10.1006/jmbi.1997.1621  1
1998 Figini M, Obici L, Mezzanzanica D, Griffiths A, Colnaghi MI, Winter G, Canevari S. Panning phage antibody libraries on cells: isolation of human Fab fragments against ovarian carcinoma using guided selection. Cancer Research. 58: 991-6. PMID 9500461  1
1998 Krebs B, Griffin H, Winter G, Rose-John S. Recombinant human single chain Fv antibodies recognizing human interleukin-6. Specific targeting of cytokine-secreting cells. The Journal of Biological Chemistry. 273: 2858-65. PMID 9446596 DOI: 10.1074/jbc.273.5.2858  1
1998 Hartmann G, Prospero T, Brinkmann V, Ozcelik C, Winter G, Hepple J, Batley S, Bladt F, Sachs M, Birchmeier C, Birchmeier W, Gherardi E, Ozcelik O. Engineered mutants of HGF/SF with reduced binding to heparan sulphate proteoglycans, decreased clearance and enhanced activity in vivo. Current Biology : Cb. 8: 125-34. PMID 9443912  1
1997 FitzGerald K, Holliger P, Winter G. Improved tumour targeting by disulphide stabilized diabodies expressed in Pichia pastoris. Protein Engineering. 10: 1221-5. PMID 9488147  1
1997 Holliger P, Winter G. Diabodies: small bispecific antibody fragments. Cancer Immunology, Immunotherapy : Cii. 45: 128-30. PMID 9435855 DOI: 10.1007/s002620050414  1
1997 Doorbar J, Foo C, Coleman N, Medcalf L, Hartley O, Prospero T, Napthine S, Sterling J, Winter G, Griffin H. Characterization of events during the late stages of HPV16 infection in vivo using high-affinity synthetic Fabs to E4. Virology. 238: 40-52. PMID 9375007 DOI: 10.1006/viro.1997.8768  1
1997 Neri D, Carnemolla B, Nissim A, Leprini A, Querzè G, Balza E, Pini A, Tarli L, Halin C, Neri P, Zardi L, Winter G. Targeting by affinity-matured recombinant antibody fragments of an angiogenesis associated fibronectin isoform. Nature Biotechnology. 15: 1271-5. PMID 9359110 DOI: 10.1038/nbt1197-1271  1
1997 Corbett SJ, Tomlinson IM, Sonnhammer EL, Buck D, Winter G. Sequence of the human immunoglobulin diversity (D) segment locus: a systematic analysis provides no evidence for the use of DIR segments, inverted D segments, "minor" D segments or D-D recombination. Journal of Molecular Biology. 270: 587-97. PMID 9245589 DOI: 10.1006/jmbi.1997.1141  1
1997 Kontermann RE, Martineau P, Cummings CE, Karpas A, Allen D, Derbyshire E, Winter G. Enzyme immunoassays using bispecific diabodies. Immunotechnology : An International Journal of Immunological Engineering. 3: 137-44. PMID 9237098 DOI: 10.1016/S1380-2933(97)00010-9  1
1997 Holliger P, Wing M, Pound JD, Bohlen H, Winter G. Retargeting serum immunoglobulin with bispecific diabodies. Nature Biotechnology. 15: 632-6. PMID 9219264 DOI: 10.1038/nbt0797-632  1
1997 Kontermann RE, Wing MG, Winter G. Complement recruitment using bispecific diabodies. Nature Biotechnology. 15: 629-31. PMID 9219263 DOI: 10.1038/nbt0797-629  1
1997 Hawkins RE, Russell SJ, Marcus R, Ashworth LJ, Brissnik J, Zhang J, Winter G, Bleehen NM, Shaw MM, Williamson L, Ouwehand W, Stevenson F, Hamblin T, Oscier D, Zhu D, et al. A pilot study of idiotypic vaccination for follicular B-cell lymphoma using a genetic approach. CRC NO: 92/33. Protocol NO: PH1/027. Human Gene Therapy. 8: 1287-99. PMID 9215745 DOI: 10.1089/hum.1997.8.10-1287  1
1997 Frippiat JP, Dard P, Marsh S, Winter G, Lefranc MP. Immunoglobulin lambda light chain orphons on human chromosome 8q11.2. European Journal of Immunology. 27: 1260-5. PMID 9174619 DOI: 10.1002/eji.1830270530  1
1997 Ignatovich O, Tomlinson IM, Jones PT, Winter G. The creation of diversity in the human immunoglobulin V(lambda) repertoire. Journal of Molecular Biology. 268: 69-77. PMID 9149142 DOI: 10.1006/jmbi.1997.0956  1
1997 Zaccolo M, Griffiths AP, Prospero TD, Winter G, Gherardi E. Dimerization of Fab fragments enables ready screening of phage antibodies that affect hepatocyte growth factor/scatter factor activity on target cells. European Journal of Immunology. 27: 618-23. PMID 9079800 DOI: 10.1002/eji.1830270307  1
1996 Ueda H, Tsumoto K, Kubota K, Suzuki E, Nagamune T, Nishimura H, Schueler PA, Winter G, Kumagai I, Mahoney WC. Open sandwich ELISA: A novel immunoassay based on the interchain interaction of antibody variable region Nature Biotechnology. 14: 1714-1718. PMID 9634858  1
1996 Neri D, Petrul H, Winter G, Light Y, Marais R, Britton KE, Creighton AM. Radioactive labeling of recombinant antibody fragments by phosphorylation using human casein kinase II and [γ-32P]-ATP Nature Biotechnology. 14: 485-490. PMID 9630925  1
1996 Williams SC, Frippiat JP, Tomlinson IM, Ignatovich O, Lefranc MP, Winter G. Sequence and evolution of the human germline Vλ repertoire Journal of Molecular Biology. 264: 220-232. PMID 8951372 DOI: 10.1006/jmbi.1996.0636  1
1996 Carnemolla B, Neri D, Castellani P, Leprini A, Neri G, Pini A, Winter G, Zardi L. Phage antibodies with pan-species recognition of the oncofoetal angiogenesis marker fibronectin ED-B domain International Journal of Cancer. 68: 397-405. PMID 8903484 DOI: 10.1002/(SICI)1097-0215(19961104)68:3<397::AID-IJC20>3.0.CO;2-4  1
1996 Neri D, Prospero T, Petrul H, Winter G, Browne M, Vanderpant L. Multipurpose high sensitivity luminescence analyzer (LUANA): Use in gel electrophoresis Biotechniques. 20: 708-713. PMID 8800693  1
1996 Low NM, Holliger P, Winter G. Mimicking somatic hypermutation: Affinity maturation of antibodies displayed on bacteriophage using a bacterial mutator strain Journal of Molecular Biology. 260: 359-368. PMID 8757799 DOI: 10.1006/jmbi.1996.0406  1
1996 Fisch I, Kontermann RE, Finnern R, Hartley O, Soler-Gonzalez AS, Griffiths AD, Winter G. A strategy of exon shuffling for making large peptide repertoires displayed on filamentous bacteriophage Proceedings of the National Academy of Sciences of the United States of America. 93: 7761-7766. PMID 8755549 DOI: 10.1073/pnas.93.15.7761  1
1996 Harrison JL, Williams SC, Winter G, Nissim A. Screening of phage antibody libraries Methods in Enzymology. 267: 83-108. PMID 8743311  1
1996 Holliger P, Brissinck J, Williams RL, Thielemans K, Winter G. Specific killing of lymphoma cells by cytotoxic T-cells mediated by a bispecific diabody Protein Engineering. 9: 299-305. PMID 8736497  1
1996 Bruggeman YE, Boogert A, Van Hoek A, Jones PT, Winter G, Schots A, Hilhorst R. Phage antibodies against an unstable hapten: Oxygen sensitive reduced flavin Febs Letters. 388: 242-244. PMID 8690096 DOI: 10.1016/0014-5793(96)00544-3  1
1996 Tomlinson IM, Walter G, Jones PT, Dear PH, Sonnhammer ELL, Winter G. The imprint of somatic hypermutation on the repertoire of human germline V genes Journal of Molecular Biology. 256: 813-817. PMID 8601832 DOI: 10.1006/jmbi.1996.0127  1
1996 Nissim A, Neri D, Winter G. Development and usage of semi-synthetic scFv repertoires displayed on phage Human Antibodies and Hybridomas. 7: XXVIII.  1
1995 Neri D, de Lalla C, Petrul H, Neri P, Winter G. Calmodulin as a versatile tag for antibody fragments. Bio/Technology (Nature Publishing Company). 13: 373-7. PMID 9634779 DOI: 10.1038/nbt0495-373  1
1995 Fippiat JP, Williams SC, Tomlinson LM, Cook GP, Cherif D, Paslier DL, Collins JE, Dunham L, Winter G, Lefranc MP. Organization of the human immunoglobulin lambda light-chain locus on chromosome 22q11.2 Human Molecular Genetics. 4: 983-991. PMID 7655473 DOI: 10.1093/hmg/4.6.983  1
1995 Neri D, Momo M, Prospero T, Winter G. High-affinity Antigen Binding by Chelating Recombinant Antibodies (CRAbs) Journal of Molecular Biology. 246: 367-373. PMID 7533215 DOI: 10.1006/jmbi.1994.0091  1
1995 Tomlinson IM, Cook GP, Walter G, Carter NP, Riethman H, Buluwela L, Rabbitts TH, Winter G. A complete map of the human immunoglobulin V(H) locus Annals of the New York Academy of Sciences. 764: 43-46. PMID 7486559  1
1995 Walter G, Tomlinson IM, Dear PH, Sonnhammer ELL, Cook GP, Winter G. Comparison of the human germline and rearranged V(H) repertoire reveals complementarity between germline variability and somatic mutation Annals of the New York Academy of Sciences. 764: 180-182. PMID 7486518  1
1994 Figini M, Marks JD, Winter G, Griffiths AD. In vitro assembly of repertoires of antibody chains on the surface of phage by renaturation Journal of Molecular Biology. 239: 68-78. PMID 8196048 DOI: 10.1006/jmbi.1994.1351  1
1994 Hawkins RE, Zhu D, Ovecka M, Winter G, Hamblin TJ, Long A, Stevenson FK. Idiotypic vaccination against human B-cell lymphoma. Rescue of variable region gene sequences from biopsy material for assembly as single-chain Fv personal vaccines Blood. 83: 3279-3288. PMID 8193363  1
1994 Soumillion P, Jespers L, Bouchet M, Marchand-Brynaert J, Winter G, Fastrez J. Selection of β-lactamase on filamentous bacteriophage by catalytic activity Journal of Molecular Biology. 237: 415-422. PMID 8151702 DOI: 10.1006/jmbi.1994.1244  1
1994 Cox JPL, Tomlinson IM, Winter G. A directory of human germ-line VN segments reveals a strong bias in their usage European Journal of Immunology. 24: 827-836. PMID 8149953  1
1994 Griffiths AD, Williams SC, Hartley O, Tomlinson IM, Waterhouse P, Crosby WL, Kontermann RE, Jones PT, Low NM, Allison TJ. Isolation of high affinity human antibodies directly from large synthetic repertoires. The Embo Journal. 13: 3245-60. PMID 8045255  1
1994 Winter G, Griffiths AD, Hawkins RE, Hoogenboom HR. Making antibodies by phage display technology Annual Review of Immunology. 12: 433-455. PMID 8011287  1
1994 Doorbar J, Winter G. Isolation of a peptide antagonist to the thrombin receptor using phage display Journal of Molecular Biology. 244: 361-369. PMID 7990127 DOI: 10.1006/jmbi.1994.1736  1
1994 Tomlinson IM, Cook GP, Carter NP, Elaswarapu R, Smith S, Walter G, Buluwela L, Rabbitts TH, Winter G. Human immunoglobulin VH and D segments on chromosomes 15q11.2 and 16p11.2 Human Molecular Genetics. 3: 853-860. PMID 7951227 DOI: 10.1093/hmg/3.6.853  1
1994 Cook GP, Tomlinson IM, Walter G, Riethman H, Carter NP, Buluwela L, Winter G, Rabbitts TH. A map of the human immunoglobulin VH locus completed by analysis of the telomeric region of chromosome 14q Nature Genetics. 7: 162-168. PMID 7920635  1
1994 Chester KA, Begent RHJ, Robson L, Keep PA, Pedley RB, Boden LIBiol JA, Boxer G, Green A, Winter G, Cochet O, Hawkins RE. Phage libraries for generation of clinically useful antibodies The Lancet. 343: 455-456. PMID 7905958 DOI: 10.1016/S0140-6736(94)92695-6  1
1994 Perisic O, Webb PA, Holliger P, Winter G, Williams RL. Crystal structure of a diabody, a bivalent antibody fragment Structure. 2: 1217-1226. PMID 7704531 DOI: 10.1016/S0969-2126(94)00123-5  1
1994 Jespers LS, Roberts A, Mahler SM, Winter G, Hoogenboom HR. Guiding the selection of human antibodies from phage display repertoires to a single epitope of an antigen Nature Biotechnology. 12: 899-903. PMID 7521646  1
1994 Nissim A, Hoogenboom HR, Tomlinson IM, Flynn G, Midgley C, Lane D, Winter G. Antibody fragments from a 'single pot' phage display library as immunochemical reagents Embo Journal. 13: 692-698. PMID 7508862  1
1993 Marks JD, Ouwehand WH, Bye JM, Finnem R, Gorick BD, Voak D, Thorpe SJ, Hughes-Jones NC, Winter G. Human antibody fragments specific for human blood group antigens from a phage display library Nature Biotechnology. 11: 1145-1149.  1
1989 Brüggemann M, Winter G, Waldmann H, Neuberger MS. The immunogenicity of chimeric antibodies. The Journal of Experimental Medicine. 170: 2153-7. PMID 2584938  0.36
1988 Fersht AR, Knill-Jones JW, Bedouelle H, Winter G. Reconstruction by site-directed mutagenesis of the transition state for the activation of tyrosine by the tyrosyl-tRNA synthetase: A mobile loop envelopes the transition state in an induced-fit mechanism Biochemistry. 27: 1581-1587. PMID 3284584  1
1986 Bedouelle H, Winter G. A model of synthetase/transfer RNA interaction as deduced by protein engineering Nature. 320: 371-373. PMID 3960121 DOI: 10.1038/320371a0  1
1986 Jones PT, Dear PH, Foote J, Neuberger MS, Winter G. Replacing the complementarity-determining regions in a human antibody with those from a mouse. Nature. 321: 522-5. PMID 3713831 DOI: 10.1038/321522a0  0.36
1986 Waye MM, Winter G. A transcription terminator in the 5' non-coding region of the tyrosyl tRNA synthetase gene from Bacillus stearothermophilus. European Journal of Biochemistry. 158: 505-10. PMID 3525162  0.4
1986 Carter P, Bedouelle H, Winter G. Construction of heterodimer tyrosyl-tRNA synthetase shows tRNA(Tyr) interacts with both subunits Proceedings of the National Academy of Sciences of the United States of America. 83: 1189-1192. PMID 3006039  1
1985 Bedouelle H, Carter P, Waye MM, Winter G, Lowe DM, Wilkinson AJ, Fersht AR. Engineering of tyrosyl tRNA synthetase. Biochimie. 67: 737-43. PMID 3910110  0.44
1985 Fersht AR, Shi JP, Knill-Jones J, Lowe DM, Wilkinson AJ, Blow DM, Brick P, Carter P, Waye MM, Winter G. Hydrogen bonding and biological specificity analysed by protein engineering. Nature. 314: 235-8. PMID 3845322  0.44
1985 Waye MM, Verhoeyen ME, Jones PT, Winter G. EcoK selection vectors for shotgun cloning into M13 and deletion mutagenesis. Nucleic Acids Research. 13: 8561-71. PMID 3001643  0.4
1985 Carter P, Bedouelle H, Winter G. Improved oligonudeotide site-directed rautagenesis using M13 vectors Nucleic Acids Research. 13: 4431-4443. PMID 2989795 DOI: 10.1093/nar/13.12.4431  1
1984 Winter G, Carter P, Waye MM, Blow DM, Wilkinson AJ, Shi JP, Fersht AR. Genetic dissection of tyrosyl-tRNA synthetase. Biochemical Society Transactions. 12: 224-5. PMID 6724115  0.44
1983 Winter G, Koch GL, Hartley BS, Barker DG. The amino acid sequence of the tyrosyl-tRNA synthetase from Bacillus stearothermophilus. European Journal of Biochemistry / Febs. 132: 383-7. PMID 6840095  1
1983 Waye MM, Winter G, Wilkinson AJ, Fersht AR. Deletion mutagenesis using an 'M13 splint': the N-terminal structural domain of tyrosyl-tRNA synthetase (B. stearothermophilus) catalyses the formation of tyrosyl adenylate. The Embo Journal. 2: 1827-9. PMID 6315404  0.4
1981 Winter G, Fields S, Brownlee GG. Nucleotide sequence of the haemagglutinin gene of a human influenza virus H1 subtype. Nature. 292: 72-5. PMID 7278968  0.88
1981 Winter G, Fields S, Gait MJ, Brownlee GG. The use of synthetic oligodeoxynucleotide primers in cloning and sequencing segment of 8 influenza virus (A/PR/8/34). Nucleic Acids Research. 9: 237-45. PMID 7208353  0.88
1981 Fields S, Winter G, Brownlee GG. Structure of the neuraminidase gene in human influenza virus A/PR/8/34. Nature. 290: 213-7. PMID 7010182  0.88
1978 Winter G, Brownlee GG. 3'End labelling of RNA with 32P suitable for rapid gel sequencing. Nucleic Acids Research. 5: 3129-39. PMID 360168  0.88
1977 Winter GP, Hartley BS. The amino acid sequence of tryptophanyl tRNA synthetase from Bacillus stearothermophilus. Febs Letters. 80: 340-2. PMID 891985 DOI: 10.1016/0014-5793(77)80471-7  1
1977 Winter GP, Hartley BS, McLachlan AD, Lee M, Muench KH. Sequence homologies between the tryptophanyl tRNA synthetases of Bacillus stearothermophilus and Escherichia coli. Febs Letters. 82: 348-50. PMID 334569 DOI: 10.1016/0014-5793(77)80618-2  1
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