Karen E. Asin, Ph.D. - Publications

Affiliations: 
Takeda Pharmaceutical 

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2003 Wirtshafter D, Asin KE. Effects of haloperidol and clozapine on Fos expression in the primate striatum. Neuroreport. 14: 2429-32. PMID 14663205 DOI: 10.1097/00001756-200312190-00028  0.682
2001 Wirtshafter D, Asin KE. Comparative effects of scopolamine and quinpirole on the striatal fos expression induced by stimulation of D(1) dopamine receptors in the rat. Brain Research. 893: 202-14. PMID 11223008 DOI: 10.1016/S0006-8993(00)03315-1  0.706
1999 Wirtshafter D, Asin KE. Haloperidol induces Fos expression in the globus pallidus and substantia nigra of cynomolgus monkeys. Brain Research. 835: 154-61. PMID 10415370 DOI: 10.1016/S0006-8993(99)01550-4  0.682
1999 Wirtshafter D, Asin KE. Unilateral dopamine depletion paradoxically enhances amphetamine-induced Fos expression in basal ganglia output structures. Brain Research. 824: 81-8. PMID 10095045 DOI: 10.1016/S0006-8993(99)01091-4  0.698
1997 Wirtshafter D, Schardt G, Asin KE. Compartmentally specific effects of quinpirole on the striatal Fos expression induced by stimulation of D1-dopamine receptors in intact rats. Brain Research. 771: 271-7. PMID 9401747 DOI: 10.1016/S0006-8993(97)00795-6  0.696
1997 Asin KE, Domino EF, Nikkel A, Shiosaki K. The selective dopamine D1 receptor agonist A-86929 maintains efficacy with repeated treatment in rodent and primate models of Parkinson's disease. The Journal of Pharmacology and Experimental Therapeutics. 281: 454-9. PMID 9103530  0.313
1996 Shiosaki K, Asin KE, Britton DR, Giardina WJ, Bednarz L, Mahan L, Mikusa J, Nikkel A, Wismer C. Hyperactivity and behavioral seizures in rodents following treatment with the dopamine D1 receptor agonists A-86929 and ABT-431. European Journal of Pharmacology. 317: 183-90. PMID 8997599 DOI: 10.1016/S0014-2999(96)00718-2  0.434
1996 Asin KE, Bednarz L, Nikkel AL. MK-801 differentially affects dopamine D1 and D2 receptor agonist-induced behavioral tolerance and desensitization. Brain Research. 725: 67-74. PMID 8828587 DOI: 10.1016/0006-8993(96)00348-4  0.447
1996 Asin KE, Wirtshafter D, Nikkel A. Amphetamine induces Fos-like immunoreactivity in the striatum of primates. Brain Research. 719: 138-42. PMID 8782873 DOI: 10.1016/0006-8993(96)00140-0  0.69
1995 Asin KE, Bednarz L, Nikkel A, Perner R. Rotation and striatal c-fos expression after repeated, daily treatment with selective dopamine receptor agonists and levodopa. The Journal of Pharmacology and Experimental Therapeutics. 273: 1483-90. PMID 7791123  0.345
1995 Wirtshafter D, Asin KE. Dopamine antagonists induce fos-like-immunoreactivity in the substantia nigra and entopeduncular nucleus of the rat. Brain Research. 670: 205-14. PMID 7743187 DOI: 10.1016/0006-8993(94)01280-U  0.686
1995 Michaelides MR, Hong Y, DiDomenico S, Asin KE, Britton DR, Lin CW, Williams M, Shiosaki K. (5aR,11bS)-4,5,5a,6,7,11b-hexahydro-2-propyl-3-thia-5-azacyclopent-1- ena[c]-phenanthrene-9,10-diol (A-86929): a potent and selective dopamine D1 agonist that maintains behavioral efficacy following repeated administration and characterization of its diacetyl prodrug (ABT-431). Journal of Medicinal Chemistry. 38: 3445-7. PMID 7658429 DOI: 10.1021/Jm00018A002  0.318
1994 Wirtshafter D, Asin KE, Pitzer MR. Dopamine agonists and stress produce different patterns of Fos-like immunoreactivity in the lateral habenula. Brain Research. 633: 21-6. PMID 8137158 DOI: 10.1016/0006-8993(94)91517-2  0.718
1994 Wirtshafter D, Asin KE. Interactive effects of stimulation of D1 and D2 dopamine receptors on fos-like immunoreactivity in the normosensitive rat striatum. Brain Research Bulletin. 35: 85-91. PMID 7953762 DOI: 10.1016/0361-9230(94)90220-8  0.671
1994 Asin KE, Nikkel AL, Wirtshafter D. Repeated D1 receptor agonist treatment blocks cocaine-induced locomotor activity and c-fos expression. Brain Research. 637: 342-4. PMID 7910104 DOI: 10.1016/0006-8993(94)91258-0  0.651
1993 Asin KE, Wirtshafter D. Effects of repeated dopamine D1 receptor stimulation on rotation and c-fos expression. European Journal of Pharmacology. 235: 167-8. PMID 8100194 DOI: 10.1016/0014-2999(93)90840-E  0.686
1992 Asin KE, Gore PA, Bednarz L, Holladay M, Nadzan AM. Effects of selective CCK receptor agonists on food intake after central or peripheral administration in rats. Brain Research. 571: 169-74. PMID 1611492 DOI: 10.1016/0006-8993(92)90527-G  0.368
1992 Asin KE, Bednarz L, Nikkel AL, Gore PA, Nadzan AM. A-71623, a selective CCK-A receptor agonist, suppresses food intake in the mouse, dog, and monkey. Pharmacology, Biochemistry, and Behavior. 42: 699-704. PMID 1513850 DOI: 10.1016/0091-3057(92)90017-A  0.32
1992 Asin KE, Davis JD, Bednarz L. Differential effects of serotonergic and catecholaminergic drugs on ingestive behavior. Psychopharmacology. 109: 415-21. PMID 1365856 DOI: 10.1007/Bf02247717  0.389
1992 Kebabian JW, DeNinno MP, Schoenleber R, MacKenzie R, Britton DR, Asin KE. A68930: a potent agonist specific for the dopamine D1 receptor. Neurochemistry International. 20: 157S-160S. PMID 1365416 DOI: 10.1016/0197-0186(92)90230-O  0.379
1991 Wirtshafter D, Asin KE. Dissociation of haloperidol-induced "anhedonia" and catalepsy by lesions of the dorsal raphe nucleus. Pharmacology, Biochemistry, and Behavior. 40: 1001-4. PMID 1816554 DOI: 10.1016/0091-3057(91)90119-M  0.723
1991 DeNinno MP, Schoenleber R, MacKenzie R, Britton DR, Asin KE, Briggs C, Trugman JM, Ackerman M, Artman L, Bednarz L. A68930: a potent agonist selective for the dopamine D1 receptor. European Journal of Pharmacology. 199: 209-19. PMID 1683288 DOI: 10.1016/0014-2999(91)90459-4  0.413
1990 Asin KE, Wirtshafter D. Evidence for dopamine involvement in reinforcement obtained using a latent extinction paradigm. Pharmacology, Biochemistry, and Behavior. 36: 417-20. PMID 2356217 DOI: 10.1016/0091-3057(90)90426-I  0.668
1990 Asin KE, Bednarz L, Montana W. Rotation in response to selective dopamine receptor agonists in rats with electrolytic substantia nigra lesions. Life Sciences. 46: 1817-23. PMID 1972973 DOI: 10.1016/0024-3205(90)90232-G  0.357
1989 Asin KE, Montana WE. Studies on D1 and D2 dopamine receptor involvement in conditioned taste aversions. Pharmacology, Biochemistry, and Behavior. 32: 1033-41. PMID 2572001 DOI: 10.1016/0091-3057(89)90077-4  0.33
1989 Kerkman DJ, Ackerman M, Artman LD, MacKenzie RG, Johnson MC, Bednarz L, Montana W, Asin KE, Stampfli H, Kebabian JW. A-69024: a non-benzazepine antagonist with selectivity for the dopamine D-1 receptor. European Journal of Pharmacology. 166: 481-91. PMID 2509217 DOI: 10.1016/0014-2999(89)90362-2  0.385
1988 Asin KE, Montana WE. Rotation following intranigral injections of a selective D1 or a selective D2 dopamine receptor agonist in rats. Pharmacology, Biochemistry, and Behavior. 29: 89-92. PMID 3258427 DOI: 10.1016/0091-3057(88)90279-1  0.312
1988 Wirtshafter D, Klitenick MA, Asin KE. Is dopamine involved in the hyperactivity produced by injections of muscimol into the median raphe nucleus? Pharmacology, Biochemistry, and Behavior. 30: 577-83. PMID 3211966 DOI: 10.1016/0091-3057(88)90068-8  0.68
1987 Wirtshafter D, Stratford TR, Asin KE. Evidence that serotonergic projections to the substantia nigra in the rat arise in the dorsal, but not the median, raphe nucleus. Neuroscience Letters. 77: 261-6. PMID 3039416 DOI: 10.1016/0304-3940(87)90509-X  0.659
1987 Wirtshafter D, Klitenick MA, Asin KE. Evidence against serotonin involvement in the hyperactivity produced by injections of muscimol into the median raphe nucleus. Pharmacology, Biochemistry, and Behavior. 27: 45-52. PMID 2441421 DOI: 10.1016/0091-3057(87)90475-8  0.689
1986 Wirtshafter D, Montana W, Asin KE. Behavioral and biochemical studies of the substrates of median raphe lesion induced hyperactivity. Physiology & Behavior. 38: 751-9. PMID 3823192 DOI: 10.1016/0031-9384(86)90039-9  0.686
1986 Wirtshafter D, Asin KE. Discrimination learning and reversal following electrolytic lesions of the median raphe nucleus. Physiology & Behavior. 37: 213-9. PMID 3737730 DOI: 10.1016/0031-9384(86)90223-4  0.664
1986 Wirtshafter D, Asin KE, Lorens SA. Serotonin-immunoreactive projections to the hippocampus from the interpeduncular nucleus in the rat. Neuroscience Letters. 64: 259-62. PMID 2421209 DOI: 10.1016/0304-3940(86)90338-1  0.634
1986 Wirtshafter D, Asin KE. Serotonin depletion and inhibition: Running the rat race without any brakes? Behavioral and Brain Sciences. 9: 347-348. DOI: 10.1017/S0140525X00023037  0.65
1985 Asin KE, Wirtshafter D, Fibiger HC. Electrolytic, but not 5,7-dihydroxytryptamine, lesions of the nucleus medianus raphe impair acquisition of a radial maze task. Behavioral and Neural Biology. 44: 415-24. PMID 4084186 DOI: 10.1016/S0163-1047(85)90784-8  0.734
1985 Asin KE, Wirtshafter D, Tabakoff B. Pentobarbital-induced drinking does not rely on a renal dipsogen. Physiology & Behavior. 34: 151-3. PMID 4041049 DOI: 10.1016/0031-9384(85)90094-0  0.653
1985 Wirtshafter D, Asin KE. Haloperidol and nonreinforcement produce different patterns of response slowing in a food reinforced runway task. Pharmacology, Biochemistry, and Behavior. 22: 661-3. PMID 4011630 DOI: 10.1016/0091-3057(85)90509-X  0.643
1985 Asin KE, Wirtshafter D, Tabakoff B. Failure to establish a conditioned place preference with ethanol in rats. Pharmacology, Biochemistry, and Behavior. 22: 169-73. PMID 3983210 DOI: 10.1016/0091-3057(85)90372-7  0.632
1985 Asin KE, Wirtshafter D. Clonidine produces a conditioned place preference in rats. Psychopharmacology. 85: 383-5. PMID 3923526 DOI: 10.1007/Bf00428206  0.63
1984 Asin KE, Fibiger HC. Force requirements in lever-pressing and responding after haloperidol. Pharmacology, Biochemistry, and Behavior. 20: 323-6. PMID 6709668 DOI: 10.1016/0091-3057(84)90264-8  0.483
1984 Asin KE, Satoh K, Fibiger HC. Regional cerebellar choline acetyltransferase activity following peduncular lesions. Experimental Brain Research. 53: 370-3. PMID 6705869 DOI: 10.1007/BF00238167  0.532
1984 Asin KE, Fibiger HC. Spontaneous and delayed spatial alternation following damage to specific neuronal elements within the nucleus medianus raphe. Behavioural Brain Research. 13: 241-50. PMID 6508902 DOI: 10.1016/0166-4328(84)90166-9  0.596
1983 Asin KE, Fibiger HC. An analysis of neuronal elements within the median nucleus of the raphe that mediate lesion-induced increases in locomotor activity. Brain Research. 268: 211-23. PMID 6871682 DOI: 10.1016/0006-8993(83)90487-0  0.594
1983 Wirtshafter D, Asin KE. Impaired radial maze performance in rats with electrolytic median raphe lesions. Experimental Neurology. 79: 412-21. PMID 6822272 DOI: 10.1016/0014-4886(83)90222-4  0.687
1982 Asin KE, Wirtshafter D, Fibiger HC. Alterations in drug induced catalepsy and post-decapitation convulsions following brain and spinal cord depletion of norepinephrine by the neurotoxin DSP-4. Life Sciences. 30: 1531-6. PMID 7200562 DOI: 10.1016/0024-3205(82)90240-5  0.694
1982 Wirtshafter D, Asin KE. Evidence that electrolytic median raphe lesions increase locomotion but not exploration. Physiology & Behavior. 28: 749-54. PMID 7100276 DOI: 10.1016/0031-9384(82)90189-5  0.698
1982 Asin KE, Wirtshafter D. Ingestive behaviors of rats with electrolytic median raphe lesions maintained on a food deprivation schedule. Physiology & Behavior. 28: 89-93. PMID 7079330 DOI: 10.1016/0031-9384(82)90108-1  0.697
1982 Wirtshafter D, Asin KE. A comment on the practice of expressing food and water intake as a proportion of body weight. Physiology & Behavior. 28: 183-5. PMID 7079316 DOI: 10.1016/0031-9384(82)90122-6  0.534
1981 Davis JD, Wirtshafter D, Asin KE, Brief D. Sustained intracerebroventricular infusion of brain fuels reduces body weight and food intake in rats. Science (New York, N.Y.). 212: 81-3. PMID 7193909 DOI: 10.1126/Science.7193909  0.597
1981 Wirtschafter D, Asin KE. Shock-induced suppression of drinking following electrolytic median raphe lesions Physiological Psychology. 9: 263-268. DOI: 10.3758/Bf03326974  0.517
1980 Asin KE, Wirtshafter D, Kent EW. The effects of electrolytic median raphe lesions on two measures of latent inhibition. Behavioral and Neural Biology. 28: 408-17. PMID 7406802 DOI: 10.1016/S0163-1047(80)91734-3  0.793
1980 Asin KE. Lysine vasopressin attenuation of diethyldithiocarbamate-induced amnesia. Pharmacology, Biochemistry, and Behavior. 12: 343-6. PMID 6248894 DOI: 10.1016/0091-3057(80)90034-9  0.406
1979 Asin KE, Wirtshafter D, Kent EW. Impaired patterned responding in rats with electrolytic median raphe lesions. Physiology & Behavior. 23: 803-6. PMID 504480 DOI: 10.1016/0031-9384(79)90179-3  0.803
1979 Wirtshafter D, Asin K, Kent EW. Simple technique for midline stereotaxis surgery in the rat. Physiology & Behavior. 23: 409-10. PMID 504430 DOI: 10.1016/0031-9384(79)90388-3  0.736
1979 Asin KE, Wirtshafter D, Kent EW. Straight alley acquisition and extinction and open field activity following discrete electrolytic lesions of the mesencephalic raphe nuclei. Behavioral and Neural Biology. 25: 242-56. PMID 464976 DOI: 10.1016/S0163-1047(79)90597-1  0.802
1978 Wirtshafter D, Asin KE, Kent EW. Nucleus accumbens lesions reduce amphetamine hyperthermia but not hyperactivity. European Journal of Pharmacology. 51: 449-52. PMID 710513 DOI: 10.1016/0014-2999(78)90437-5  0.807
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