| Year |
Citation |
Score |
| 2015 |
Uchiyama S, Döhrmann S, Timmer AM, Dixit N, Ghochani M, Bhandari T, Timmer JC, Sprague K, Bubeck-Wardenburg J, Simon SI, Nizet V. Streptolysin O Rapidly Impairs Neutrophil Oxidative Burst and Antibacterial Responses to Group A Streptococcus. Frontiers in Immunology. 6: 581. PMID 26635795 DOI: 10.3389/Fimmu.2015.00581 |
0.697 |
|
| 2013 |
Crotty Alexander LE, Marsh BJ, Timmer AM, Lin AE, Zainabadi K, Czopik A, Guarente L, Nizet V. Myeloid cell sirtuin-1 expression does not alter host immune responses to Gram-negative endotoxemia or Gram-positive bacterial infection. Plos One. 8: e84481. PMID 24386389 DOI: 10.1371/Journal.Pone.0084481 |
0.72 |
|
| 2012 |
Cole JN, Aziz RK, Kuipers K, Timmer AM, Nizet V, van Sorge NM. A conserved UDP-glucose dehydrogenase encoded outside the hasABC operon contributes to capsule biogenesis in group A Streptococcus. Journal of Bacteriology. 194: 6154-61. PMID 22961854 DOI: 10.1128/Jb.01317-12 |
0.771 |
|
| 2011 |
Ali SR, Timmer AM, Bilgrami S, Park EJ, Eckmann L, Nizet V, Karin M. Anthrax toxin induces macrophage death by p38 MAPK inhibition but leads to inflammasome activation via ATP leakage. Immunity. 35: 34-44. PMID 21683629 DOI: 10.1016/J.Immuni.2011.04.015 |
0.66 |
|
| 2011 |
Hsu LC, Enzler T, Seita J, Timmer AM, Lee CY, Lai TY, Yu GY, Lai LC, Temkin V, Sinzig U, Aung T, Nizet V, Weissman IL, Karin M. IL-1β-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKβ. Nature Immunology. 12: 144-50. PMID 21170027 DOI: 10.1038/Ni.1976 |
0.508 |
|
| 2010 |
Hollands A, Pence MA, Timmer AM, Osvath SR, Turnbull L, Whitchurch CB, Walker MJ, Nizet V. Genetic switch to hypervirulence reduces colonization phenotypes of the globally disseminated group A streptococcus M1T1 clone. The Journal of Infectious Diseases. 202: 11-9. PMID 20507231 DOI: 10.1086/653124 |
0.733 |
|
| 2010 |
Crotty Alexander LE, Maisey HC, Timmer AM, Rooijakkers SH, Gallo RL, von Köckritz-Blickwede M, Nizet V. M1T1 group A streptococcal pili promote epithelial colonization but diminish systemic virulence through neutrophil extracellular entrapment. Journal of Molecular Medicine (Berlin, Germany). 88: 371-81. PMID 19960175 DOI: 10.1007/S00109-009-0566-9 |
0.79 |
|
| 2009 |
Timmer AM, Timmer JC, Pence MA, Hsu LC, Ghochani M, Frey TG, Karin M, Salvesen GS, Nizet V. Streptolysin O promotes group A Streptococcus immune evasion by accelerated macrophage apoptosis. The Journal of Biological Chemistry. 284: 862-71. PMID 19001420 DOI: 10.1074/Jbc.M804632200 |
0.783 |
|
| 2008 |
Zinkernagel AS, Timmer AM, Pence MA, Locke JB, Buchanan JT, Turner CE, Mishalian I, Sriskandan S, Hanski E, Nizet V. The IL-8 protease SpyCEP/ScpC of group A Streptococcus promotes resistance to neutrophil killing. Cell Host & Microbe. 4: 170-8. PMID 18692776 DOI: 10.1016/J.Chom.2008.07.002 |
0.749 |
|
| 2008 |
Timmer AM, Nizet V. IKKbeta/NF-kappaB and the miscreant macrophage. The Journal of Experimental Medicine. 205: 1255-9. PMID 18519650 DOI: 10.1084/Jem.20081056 |
0.494 |
|
| 2008 |
Buchanan JT, Colvin KM, Vicknair MR, Patel SK, Timmer AM, Nizet V. Strain-associated virulence factors of Streptococcus iniae in hybrid-striped bass. Veterinary Microbiology. 131: 145-53. PMID 18406547 DOI: 10.1016/J.Vetmic.2008.02.027 |
0.692 |
|
| 2008 |
Gillen CM, Courtney HS, Schulze K, Rohde M, Wilson MR, Timmer AM, Guzman CA, Nizet V, Chhatwal GS, Walker MJ. Opacity factor activity and epithelial cell binding by the serum opacity factor protein of Streptococcus pyogenes are functionally discrete. The Journal of Biological Chemistry. 283: 6359-66. PMID 18180300 DOI: 10.1074/Jbc.M706739200 |
0.562 |
|
| 2007 |
Kristian SA, Timmer AM, Liu GY, Lauth X, Sal-Man N, Rosenfeld Y, Shai Y, Gallo RL, Nizet V. Impairment of innate immune killing mechanisms by bacteriostatic antibiotics. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 1107-16. PMID 17215486 DOI: 10.1096/Fj.06-6802Com |
0.737 |
|
| 2007 |
Kwinn LA, Khosravi A, Aziz RK, Timmer AM, Doran KS, Kotb M, Nizet V. Genetic characterization and virulence role of the RALP3/LSA locus upstream of the streptolysin s operon in invasive M1T1 Group A Streptococcus. Journal of Bacteriology. 189: 1322-9. PMID 17114267 DOI: 10.1128/Jb.01256-06 |
0.765 |
|
| 2006 |
Timmer AM, Kristian SA, Datta V, Jeng A, Gillen CM, Walker MJ, Beall B, Nizet V. Serum opacity factor promotes group A streptococcal epithelial cell invasion and virulence. Molecular Microbiology. 62: 15-25. PMID 16942605 DOI: 10.1111/J.1365-2958.2006.05337.X |
0.768 |
|
| 2006 |
Timmer AM, Datta V, Kristian S, Jeng A, Beall B, Nizet V. The contribution of serum opacity factor to group A streptococcal epithelial cell invasion International Congress Series. 1289: 246-249. DOI: 10.1016/j.ics.2005.11.029 |
0.76 |
|
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