| Year |
Citation |
Score |
| 2023 |
Kumar Singh P, Dangelmaier CA, Reddy Vari H, Tsygankov AY, Kunapuli SP. Biochemical characterization of spleen tyrosine kinase (SYK) isoforms in platelets. Platelets. 34: 2249549. PMID 37661351 DOI: 10.1080/09537104.2023.2249549 |
0.527 |
|
| 2023 |
Renna SA, Zhao X, Kunapuli SP, Ma P, Holinstat M, Boxer MB, Maloney DJ, Michael JV, McKenzie SE. Novel Strategy to Combat the Procoagulant Phenotype in Heparin-Induced Thrombocytopenia Using 12-LOX Inhibition. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 37345522 DOI: 10.1161/ATVBAHA.123.319434 |
0.319 |
|
| 2023 |
Dangelmaier CA, Patchin M, Vajipayajula DN, Vari HR, Singh PK, Wright MN, Kostyak JC, Tsygankov AY, Kunapuli SP. Phosphorylation of spleen tyrosine kinase (Syk) at Y346 negatively regulates ITAM-mediated signaling and function in platelets. The Journal of Biological Chemistry. 104865. PMID 37268160 DOI: 10.1016/j.jbc.2023.104865 |
0.611 |
|
| 2022 |
Kunapuli SP, Tsygankov AY. TULA-Family Regulators of Platelet Activation. International Journal of Molecular Sciences. 23. PMID 36499237 DOI: 10.3390/ijms232314910 |
0.501 |
|
| 2022 |
Amoafo EB, Entsie P, Albayati S, Dorsam GP, Kunapuli SP, Kilpatrick LE, Liverani E. Sex-related differences in the response of anti-platelet drug therapies targeting purinergic signaling pathways in sepsis. Frontiers in Immunology. 13: 1015577. PMID 36405709 DOI: 10.3389/fimmu.2022.1015577 |
0.328 |
|
| 2022 |
Dangelmaier C, Mauri B, Patel A, Kunapuli SP, Kostyak JC. D121 Located within the DRY Motif of P2Y12 Is Essential for P2Y12-Mediated Platelet Function. International Journal of Molecular Sciences. 23. PMID 36232816 DOI: 10.3390/ijms231911519 |
0.498 |
|
| 2022 |
Kostyak JC, Mauri B, Dangelmaier C, Vari HR, Patel A, Wright M, Reddy H, Tsygankov AY, Kunapuli SP. Phosphorylation on Syk Y342 is important for both ITAM and hemITAM signaling in platelets. The Journal of Biological Chemistry. 298: 102189. PMID 35753354 DOI: 10.1016/j.jbc.2022.102189 |
0.593 |
|
| 2022 |
Dangelmaier C, Vari HR, Wright M, Kostyak JC, Kunapuli SP. Clustering extent-dependent differential signaling by CLEC-2 receptors in platelets. Research and Practice in Thrombosis and Haemostasis. 6: e12710. PMID 35573643 DOI: 10.1002/rth2.12710 |
0.422 |
|
| 2022 |
Dangelmaier C, Kunapuli SP. Evidence for a PI3-kinase independent pathway in the regulation of Rap1b activation downstream of the P2Y12 receptor in platelets. Platelets. 1-6. PMID 35514261 DOI: 10.1080/09537104.2022.2071855 |
0.558 |
|
| 2021 |
Zhou J, Wu Y, Rauova L, Koma G, Wang L, Poncz M, Li H, Liu T, Fong KP, Bennett JS, Kunapuli SP, Essex DW. A novel role for endoplasmic reticulum protein 46 (ERp46) in platelet function and arterial thrombosis in mice. Blood. PMID 34752599 DOI: 10.1182/blood.2021012055 |
0.485 |
|
| 2021 |
Kostyak JC, Mauri B, Patel A, Dangelmaier C, Reddy H, Kunapuli SP. Phosphorylation of protein kinase Cδ positively regulates thromboxane generation in platelets. The Journal of Biological Chemistry. 100720. PMID 33932405 DOI: 10.1016/j.jbc.2021.100720 |
0.605 |
|
| 2020 |
Dangelmaier C, Kunapuli SP. Protease-activated receptor 4 causes Akt phosphorylation independently of PI3 kinase pathways. Platelets. 1-6. PMID 32811251 DOI: 10.1080/09537104.2020.1802415 |
0.623 |
|
| 2020 |
Szilágyi B, Fejes Z, Póliska S, Pócsi M, Czimmerer Z, Patsalos A, Fenyvesi F, Rusznyák Á, Nagy G, Kerekes G, Berhés M, Szűcs I, Kunapuli SP, Kappelmayer J, Nagy B. Reduced miR-26b Expression in Megakaryocytes and Platelets Contributes to Elevated Level of Platelet Activation Status in Sepsis. International Journal of Molecular Sciences. 21. PMID 32013235 DOI: 10.3390/Ijms21030866 |
0.429 |
|
| 2019 |
Inamdar VV, Reddy H, Dangelmaier C, Kostyak JC, Kunapuli SP. The protein tyrosine phosphatase PTPN7 is a negative regulator of ERK activation and thromboxane generation in platelets. The Journal of Biological Chemistry. PMID 31266805 DOI: 10.1074/Jbc.Ra119.007735 |
0.683 |
|
| 2019 |
Inamdar VV, Kostyak JC, Badolia R, Dangelmaier CA, Manne BK, Patel A, Kim S, Kunapuli SP. Impaired Glycoprotein VI-Mediated Signaling and Platelet Functional Responses in CD45 Knockout Mice. Thrombosis and Haemostasis. PMID 31226719 DOI: 10.1055/S-0039-1692422 |
0.468 |
|
| 2019 |
Patel A, Kostyak J, Dangelmaier C, Badolia R, Bhavanasi D, Aslan JE, Merali S, Kim S, Eble JA, Goldfinger L, Kunapuli S. ELMO1 deficiency enhances platelet function. Blood Advances. 3: 575-587. PMID 30787021 DOI: 10.1182/Bloodadvances.2018016444 |
0.854 |
|
| 2018 |
Kostyak JC, Mauri BR, Dangelmaier C, Patel A, Zhou Y, Eble JA, Tsygankov AY, McKenzie SE, Kunapuli SP. TULA-2 Deficiency Enhances Platelet Functional Responses to CLEC-2 Agonists. Th Open : Companion Journal to Thrombosis and Haemostasis. 2: e411-e419. PMID 31249969 DOI: 10.1055/s-0038-1676358 |
0.591 |
|
| 2018 |
Soroush F, Tang Y, Guglielmo K, Engelmann A, Liverani E, Langston J, Sun S, Kunapuli S, Kiani MF, Kilpatrick LE. Protein Kinase C-Delta (PKCδ) Tyrosine Phosphorylation is a Critical Regulator of Neutrophil-Endothelial Cell Interaction in Inflammation. Shock (Augusta, Ga.). PMID 30095599 DOI: 10.1097/Shk.0000000000001247 |
0.465 |
|
| 2018 |
Janapati S, Wurtzel J, Dangelmaier C, Manne BK, Bhavanasi D, Kostyak JC, Kim S, Holinstat M, Kunapuli SP, Goldfinger LE. TC21/RRas2 regulates GPVI-FcRγ-mediated platelet activation and thrombus stability. Journal of Thrombosis and Haemostasis : Jth. PMID 29883056 DOI: 10.1111/Jth.14197 |
0.836 |
|
| 2018 |
Hu L, Qi Z, Zhang S, Luo X, Kunapuli SP, Ye H, Ding Z. Response by Hu et al to Letters Regarding Article, "Platelets Express Activated P2Y Receptor in Patients With Diabetes Mellitus". Circulation. 137: 1877-1878. PMID 29685940 DOI: 10.1161/Circulationaha.117.032709 |
0.481 |
|
| 2018 |
Liverani E, Mondrinos MJ, Sun S, Kunapuli SP, Kilpatrick LE. Role of Protein Kinase C-delta in regulating platelet activation and platelet-leukocyte interaction during sepsis. Plos One. 13: e0195379. PMID 29617417 DOI: 10.1371/Journal.Pone.0195379 |
0.544 |
|
| 2018 |
Manne BK, Münzer P, Badolia R, Allgaier BW, Campbell RA, Middleton E, Weyrich AS, Kunapuli SP, Borst O, Rondina MT. PDK1 governs thromboxane generation and thrombosis in platelets by regulating activation of Raf1 in the MAPK pathway. Journal of Thrombosis and Haemostasis : Jth. PMID 29575487 DOI: 10.1111/Jth.14005 |
0.669 |
|
| 2018 |
Kostyak JC, Mauri BR, Dangelmaier CA, Patel A, Wright M, Reddy HG, Eble JA, Kunapuli SP. Dysfunctional CLEC-2 and GPVI-Mediated Signaling in Syk Y342F Knock-in Mouse Platelets Blood. 132: 3729-3729. DOI: 10.1182/Blood-2018-99-113367 |
0.657 |
|
| 2018 |
Kostyak JC, Dangelmaier CA, Mauri BR, Patel A, Kunapuli SP. Severely Impaired Platelet Function Due to a Novel Mutation of P2Y12 from a Human Subject with No History of Bleeding Blood. 132: 1130-1130. DOI: 10.1182/Blood-2018-99-113015 |
0.602 |
|
| 2017 |
Kostyak JC, Liverani E, Kunapuli SP. PKC-epsilon deficiency alters progenitor cell populations in favor of megakaryopoiesis. Plos One. 12: e0182867. PMID 28783756 DOI: 10.1371/Journal.Pone.0182867 |
0.495 |
|
| 2017 |
Badolia R, Inamdar V, Manne BK, Dangelmaier C, Kunapuli SP. Gq pathway regulates proximal C-type lectin-like receptor 2 (CLEC-2) signaling in platelets. The Journal of Biological Chemistry. PMID 28705934 DOI: 10.1074/Jbc.M117.791012 |
0.645 |
|
| 2017 |
Cho MS, Noh K, Haemmerle M, Li D, Park H, Hu Q, Hisamatsu T, Mitamura T, Mak SLC, Kunapuli S, Ma Q, Sood AK, Afshar-Kharghan V. Role of ADP receptors on platelets in the growth of ovarian cancer. Blood. PMID 28679740 DOI: 10.1182/Blood-2017-02-769893 |
0.381 |
|
| 2017 |
Hu L, Chang L, Zhang Y, Zhai L, Zhang S, Qi Z, Yan H, Yan Y, Luo X, Zhang S, Wang Y, Kunapuli SP, Ye H, Ding Z. Platelets Express Activated P2Y12 Receptor in Patients with Diabetes. Circulation. PMID 28637879 DOI: 10.1161/Circulationaha.116.026995 |
0.522 |
|
| 2017 |
Badolia R, Kostyak JC, Dangelmaier C, Kunapuli SP. Syk Activity Is Dispensable for Platelet GP1b-IX-V Signaling. International Journal of Molecular Sciences. 18. PMID 28598382 DOI: 10.3390/Ijms18061238 |
0.668 |
|
| 2017 |
Reppschläger K, Gosselin J, Dangelmaier CA, Thomas DH, Carpino N, McKenzie SE, Kunapuli SP, Tsygankov AY. TULA-2 protein phosphatase suppresses activation of Syk through the GPVI platelet receptor for collagen by dephosphorylating Tyr(P)(346), a regulatory site of Syk. The Journal of Biological Chemistry. 292: 4360. PMID 28283589 DOI: 10.1074/Jbc.A116.743732 |
0.553 |
|
| 2016 |
Zhou Y, Abraham S, Renna S, Edelstein LC, Dangelmaier CA, Tsygankov AY, Kunapuli SP, Bray PF, McKenzie SE. TULA-2 (T-Cell Ubiquitin Ligand-2) Inhibits the Platelet Fc Receptor for IgG IIA (FcγRIIA) Signaling Pathway and Heparin-Induced Thrombocytopenia in Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 27765766 DOI: 10.1161/Atvbaha.116.307979 |
0.508 |
|
| 2016 |
Reppschläger K, Gosselin J, Dangelmaier CA, Thomas DH, Carpino N, McKenzie SE, Kunapuli SP, Tsygankov AY. TULA-2 protein phosphatase suppresses activation of Syk through the GPVI platelet receptor for collagen by dephosphorylating pY346, a regulatory site of Syk. The Journal of Biological Chemistry. PMID 27609517 DOI: 10.1074/Jbc.M116.743732 |
0.643 |
|
| 2016 |
Mao G, Jin J, Kunapuli SP, Rao AK. Nuclear factor-κB regulates expression of platelet phospholipase C-β2 (PLCB2). Thrombosis and Haemostasis. 116. PMID 27465150 DOI: 10.1160/Th15-09-0749 |
0.427 |
|
| 2016 |
Liverani E, Rico MC, Tsygankov AY, Kilpatrick LE, Kunapuli SP. P2Y12 Receptor Modulates Sepsis-Induced Inflammation. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 27055904 DOI: 10.1161/Atvbaha.116.307401 |
0.507 |
|
| 2016 |
Buitrago L, Manne BK, Andre P, McKenzie S, Kunapuli S. Identification of novel Syk-independent functional roles of FcγRIIa in platelet outside-in signaling using transgenic mice expressing human FcγRIIa. Platelets. 1-3. PMID 26809427 DOI: 10.3109/09537104.2015.1119813 |
0.454 |
|
| 2016 |
Mai J, Nanayakkara G, Lopez-Pastrana J, Li X, Li YF, Wang X, Song A, Virtue A, Shao Y, Shan H, Liu F, Autieri MV, Kunapuli SP, Iwakura Y, Jiang X, et al. Interleukin-17A Promotes Aortic Endothelial Cell Activation via Transcriptionally and Post-translationally Activating p38 MAPK Pathway. The Journal of Biological Chemistry. PMID 26733204 DOI: 10.1074/Jbc.M115.690081 |
0.313 |
|
| 2016 |
Buitrago L, Manne BK, Andre P, McKenzie S, Kunapuli S. Identification of novel Syk-independent functional roles of FcγRIIa in platelet outside-in signaling using transgenic mice expressing human FcγRIIa Platelets. 1-3. DOI: 10.3109/09537104.2015.1119813 |
0.346 |
|
| 2016 |
Manne BK, Badolia R, Campbell RA, Kunapuli SP, Weyrich AS, Rondina MT. Inhibition of MAP Kinase-Interacting Kinase-1 (Mnk1) Regulates Platelet Functional Responses and Protein Synthesis in Megakaryocytes Blood. 128: 711-711. DOI: 10.1182/Blood.V128.22.711.711 |
0.644 |
|
| 2016 |
Zhou Y, Abraham S, Edelstein LC, Dangelmaier C, Tsygankov A, Kunapuli SP, Bray PF, McKenzie S. TULA-2 Inhibits the Platelet FcγRIIA-Syk Pathway and Heparin-Induced Thrombocytopenia in Mice Blood. 128: 411-411. DOI: 10.1182/Blood.V128.22.411.411 |
0.576 |
|
| 2016 |
Badolia R, Inamdar V, Manne B, Dangelmaier C, Kunapuli SP. Novel Lyn-Mediated Regulation of CLEC-2 Signaling By Gq-Coupled Receptors in Platelets Blood. 128: 2536-2536. DOI: 10.1182/Blood.V128.22.2536.2536 |
0.591 |
|
| 2016 |
Patel A, Kim S, Kostyak J, Badolia R, Dangelmaier C, Merali S, Kunapuli SP. ELMO1 Is a Novel Negative Regulator of Glycoprotein VI Signaling in Platelets Blood. 128: 2533-2533. DOI: 10.1182/Blood.V128.22.2533.2533 |
0.631 |
|
| 2016 |
Inamdar V, Kostyak J, Badolia R, Dangelmaier C, Kim S, Manne B, Kunapuli SP. Impaired GPVI Mediated Platelet Functional Responses and Signaling in CD45 Knockout Mice Blood. 128: 1355-1355. DOI: 10.1182/Blood.V128.22.1355.1355 |
0.458 |
|
| 2015 |
Kolpakov MA, Rafiq K, Guo X, Hooshdaran B, Wang T, Vlasenko L, Bashkirova YV, Zhang X, Chen X, Iftikhar S, Libonati JR, Kunapuli SP, Sabri A. Protease-activated receptor 4 deficiency offers cardioprotection after acute ischemia reperfusion injury. Journal of Molecular and Cellular Cardiology. PMID 26643815 DOI: 10.1016/J.Yjmcc.2015.11.030 |
0.416 |
|
| 2015 |
Zhou Y, Abraham S, Andre P, Edelstein LC, Shaw CA, Dangelmaier CA, Tsygankov AY, Kunapuli SP, Bray PF, McKenzie SE. Anti-miR-148a regulates platelet FcγRIIA signaling and decreases thrombosis in vivo in mice. Blood. PMID 26516227 DOI: 10.1182/Blood-2015-02-631135 |
0.489 |
|
| 2015 |
Canobbio I, Cipolla L, Guidetti GF, Manganaro D, Visconte C, Kim S, Okigaki M, Falasca M, Kunapuli SP, Torti M. The focal adhesion kinase Pyk2 links Ca2+ signalling to Src family kinase activation and protein tyrosine phosphorylation in thrombin-stimulated platelets. The Biochemical Journal. 469: 199-210. PMID 25967238 DOI: 10.1042/Bj20150048 |
0.607 |
|
| 2015 |
Manganaro D, Consonni A, Guidetti GF, Canobbio I, Visconte C, Kim S, Okigaki M, Falasca M, Hirsch E, Kunapuli SP, Torti M. Activation of phosphatidylinositol 3-kinase β by the platelet collagen receptors integrin α2β1 and GPVI: The role of Pyk2 and c-Cbl. Biochimica Et Biophysica Acta. 1853: 1879-88. PMID 25960397 DOI: 10.1016/J.Bbamcr.2015.05.004 |
0.662 |
|
| 2015 |
Bhavanasi D, Badolia R, Manne BK, Janapati S, Dangelmaier CT, Mazharian A, Jin J, Kim S, Zhang X, Chen X, Senis YA, Kunapuli SP. Cross talk between serine/threonine and tyrosine kinases regulates ADP-induced thromboxane generation in platelets. Thrombosis and Haemostasis. 114: 558-68. PMID 25947062 DOI: 10.1160/Th14-09-0775 |
0.855 |
|
| 2015 |
Alshehri OM, Montague S, Watson S, Carter P, Sarker N, Manne BK, Miller JL, Herr AB, Pollitt AY, O'Callaghan CA, Kunapuli SP, Arman M, Hughes CE, Watson SP. Activation of Glycoprotein VI (GPVI) and C-type Lectin-like receptor-2 (CLEC-2) underlies platelet activation by diesel exhaust particles and other charged/hydrophobic ligands. The Biochemical Journal. PMID 25849538 DOI: 10.1042/Bj20150192 |
0.548 |
|
| 2015 |
Zhang S, Zhang S, Hu L, Zhai L, Xue R, Ye J, Chen L, Cheng G, Mruk J, Kunapuli SP, Ding Z. Nucleotide-binding oligomerization domain 2 receptor is expressed in platelets and enhances platelet activation and thrombosis. Circulation. 131: 1160-70. PMID 25825396 DOI: 10.1161/Circulationaha.114.013743 |
0.518 |
|
| 2015 |
Kosoff RE, Aslan JE, Kostyak JC, Dulaimi E, Chow HY, Prudnikova TY, Radu M, Kunapuli SP, McCarty OJ, Chernoff J. Pak2 restrains endomitosis during megakaryopoiesis and alters cytoskeleton organization. Blood. 125: 2995-3005. PMID 25824689 DOI: 10.1182/Blood-2014-10-604504 |
0.518 |
|
| 2015 |
Manne BK, Badolia R, Dangelmaier C, Eble JA, Ellmeier W, Kahn M, Kunapuli SP. Distinct pathways regulate Syk protein activation downstream of immune tyrosine activation motif (ITAM) and hemITAM receptors in platelets. The Journal of Biological Chemistry. 290: 11557-68. PMID 25767114 DOI: 10.1074/Jbc.M114.629527 |
0.656 |
|
| 2015 |
Inamdar V, Patel A, Manne BK, Dangelmaier C, Kunapuli SP. Characterization of UBO-QIC as a Gαq inhibitor in platelets. Platelets. 26: 771-8. PMID 25734215 DOI: 10.3109/09537104.2014.998993 |
0.625 |
|
| 2015 |
Manne BK, Badolia R, Dangelmaier CA, Kunapuli SP. C-type lectin like receptor 2 (CLEC-2) signals independently of lipid raft microdomains in platelets. Biochemical Pharmacology. 93: 163-70. PMID 25462818 DOI: 10.1016/J.Bcp.2014.11.005 |
0.599 |
|
| 2015 |
Badolia R, Manne BK, Dangelmaier C, Chernoff J, Kunapuli SP. Gq-mediated Akt translocation to the membrane: a novel PIP3-independent mechanism in platelets. Blood. 125: 175-84. PMID 25331114 DOI: 10.1182/Blood-2014-05-576306 |
0.579 |
|
| 2015 |
Badolia R, Manne BK, Dangelmaier C, Kunapuli SP. IPA3 non-specifically enhances phosphorylation of several proteins in human platelets. Platelets. 26: 501-3. PMID 24750049 DOI: 10.3109/09537104.2014.902434 |
0.645 |
|
| 2015 |
Bhavanasi D, Kostyak JC, Swindle J, Kilpatrick LE, Kunapuli SP. CGX1037 is a novel PKC isoform delta selective inhibitor in platelets. Platelets. 26: 2-9. PMID 24433221 DOI: 10.3109/09537104.2013.868877 |
0.863 |
|
| 2015 |
Manganaro D, Consonni A, Guidetti GF, Canobbio I, Visconte C, Kim S, Okigaki M, Falasca M, Hirsch E, Kunapuli SP, Torti M. Activation of phosphatidylinositol 3-kinase β by the platelet collagen receptors integrin α2β1 and GPVI: The role of Pyk2 and c-Cbl Biochimica Et Biophysica Acta - Molecular Cell Research. 1853: 1879-1888. DOI: 10.1016/j.bbamcr.2015.05.004 |
0.497 |
|
| 2014 |
Kostyak JC, Bhavanasi D, Liverani E, McKenzie SE, Kunapuli SP. Protein kinase C δ deficiency enhances megakaryopoiesis and recovery from thrombocytopenia. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 2579-85. PMID 25359855 DOI: 10.1161/Atvbaha.114.304492 |
0.816 |
|
| 2014 |
Liu L, Li J, Zhang Y, Zhang S, Ye J, Wen Z, Ding J, Kunapuli SP, Luo X, Ding Z. Salvianolic acid B inhibits platelets as a P2Y12 antagonist and PDE inhibitor: evidence from clinic to laboratory. Thrombosis Research. 134: 866-76. PMID 25077998 DOI: 10.1016/J.Thromres.2014.07.019 |
0.499 |
|
| 2014 |
Newman TN, Liverani E, Ivanova E, Russo GL, Carpino N, Ganea D, Safadi F, Kunapuli SP, Tsygankov AY. Members of the novel UBASH3/STS/TULA family of cellular regulators suppress T-cell-driven inflammatory responses in vivo. Immunology and Cell Biology. 92: 837-50. PMID 25047644 DOI: 10.1038/Icb.2014.60 |
0.354 |
|
| 2014 |
Liverani E, Kilpatrick LE, Tsygankov AY, Kunapuli SP. The role of P2Y₁₂ receptor and activated platelets during inflammation. Current Drug Targets. 15: 720-8. PMID 24845219 DOI: 10.2174/1389450115666140519162133 |
0.561 |
|
| 2014 |
Simon LM, Edelstein LC, Nagalla S, Woodley AB, Chen ES, Kong X, Ma L, Fortina P, Kunapuli S, Holinstat M, McKenzie SE, Dong JF, Shaw CA, Bray PF. Human platelet microRNA-mRNA networks associated with age and gender revealed by integrated plateletomics. Blood. 123: e37-45. PMID 24523238 DOI: 10.1182/Blood-2013-12-544692 |
0.322 |
|
| 2014 |
Liverani E, Rico MC, Yaratha L, Tsygankov AY, Kilpatrick LE, Kunapuli SP. LPS-induced systemic inflammation is more severe in P2Y12 null mice. Journal of Leukocyte Biology. 95: 313-23. PMID 24142066 DOI: 10.1189/Jlb.1012518 |
0.393 |
|
| 2014 |
Zhang SH, Zhang Y, Shen J, Zhang S, Chen L, Gu J, Mruk JS, Cheng G, Zhu L, Kunapuli SP, Ding Z. Tumor vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid inhibits platelet activation and thrombosis via inhibition of thromboxane A2 signaling and phosphodiesterase. Journal of Thrombosis and Haemostasis : Jth. 11: 1855-66. PMID 23902231 DOI: 10.1111/Jth.12362 |
0.335 |
|
| 2014 |
Zhou Y, Abraham S, Andre P, Edelstein LC, Shaw C, Tsygankov A, Kunapuli SP, Bray PF, McKenzie SE. Mir-148a and Mir-25 Target TULA-2 and Regulate Human Platelet FcγRIIA Signaling Blood. 124: 337-337. DOI: 10.1182/Blood.V124.21.337.337 |
0.324 |
|
| 2014 |
Abraham S, Edelstein LC, Shaw CA, Andre P, Kong X, Dangelmaier CT, Tsygankov A, Bray PF, Kunapuli SP, McKenzie SE. Platelet FcγRIIA Signaling Results in Ubiquitination and Cellular Translocation of Activated Syk Blood. 124: 2761-2761. DOI: 10.1182/Blood.V124.21.2761.2761 |
0.648 |
|
| 2013 |
Dangelmaier C, Manne BK, Liverani E, Jin J, Bray P, Kunapuli SP. PDK1 selectively phosphorylates Thr(308) on Akt and contributes to human platelet functional responses Thrombosis and Haemostasis. 111: 508-517. PMID 24352480 DOI: 10.1160/Th13-06-0484 |
0.579 |
|
| 2013 |
Kim S, Dangelmaier C, Bhavanasi D, Meng S, Wang H, Goldfinger LE, Kunapuli SP. RhoG protein regulates glycoprotein VI-Fc receptor γ-chain complex-mediated platelet activation and thrombus formation. The Journal of Biological Chemistry. 288: 34230-8. PMID 24106269 DOI: 10.1074/Jbc.M113.504928 |
0.874 |
|
| 2013 |
Mao Y, Kunapuli SP. Trypsin causes platelet activation independently of known protease-activated receptors. Thrombosis and Haemostasis. 110: 1241-9. PMID 24030758 DOI: 10.1182/Blood.V118.21.2197.2197 |
0.742 |
|
| 2013 |
Buitrago L, Bhavanasi D, Dangelmaier C, Manne BK, Badolia R, Borgognone A, Tsygankov AY, McKenzie SE, Kunapuli SP. Tyrosine phosphorylation on spleen tyrosine kinase (Syk) is differentially regulated in human and murine platelets by protein kinase C isoforms. The Journal of Biological Chemistry. 288: 29160-9. PMID 23960082 DOI: 10.1074/Jbc.M113.464107 |
0.861 |
|
| 2013 |
Garcia AE, Rico MC, Liverani E, DeLa Cadena RA, Bray PF, Kunapuli SP. Erosive arthritis and hepatic granuloma formation induced by peptidoglycan polysaccharide in rats is aggravated by prasugrel treatment. Plos One. 8: e69093. PMID 23861957 DOI: 10.1371/Journal.Pone.0069093 |
0.357 |
|
| 2013 |
Edelstein LC, McKenzie SE, Shaw C, Holinstat MA, Kunapuli SP, Bray PF. MicroRNAs in platelet production and activation. Journal of Thrombosis and Haemostasis : Jth. 11: 340-50. PMID 23809137 DOI: 10.1111/Jth.12214 |
0.313 |
|
| 2013 |
Kim S, Cipolla L, Guidetti G, Okigaki M, Jin J, Torti M, Kunapuli SP. Distinct role of Pyk2 in mediating thromboxane generation downstream of both G12/13 and integrin αIIbβ3 in platelets. The Journal of Biological Chemistry. 288: 18194-203. PMID 23640884 DOI: 10.1074/Jbc.M113.461087 |
0.625 |
|
| 2013 |
Barauna VG, Magalhaes FC, Campos LC, Reis RI, Kunapuli SP, Costa-Neto CM, Miyakawa AA, Krieger JE. Shear stress-induced Ang II AT1 receptor activation: G-protein dependent and independent mechanisms. Biochemical and Biophysical Research Communications. 434: 647-52. PMID 23583236 DOI: 10.1016/J.Bbrc.2013.04.005 |
0.455 |
|
| 2013 |
Getz TM, Manne BK, Buitrago L, Mao Y, Kunapuli SP. Dextran sulphate induces fibrinogen receptor activation through a novel Syk-independent PI-3 kinase-mediated tyrosine kinase pathway in platelets. Thrombosis and Haemostasis. 109: 1131-40. PMID 23571309 DOI: 10.1160/Th12-09-0645 |
0.883 |
|
| 2013 |
Manne BK, Getz TM, Hughes CE, Alshehri O, Dangelmaier C, Naik UP, Watson SP, Kunapuli SP. Fucoidan is a novel platelet agonist for the C-type lectin-like receptor 2 (CLEC-2). The Journal of Biological Chemistry. 288: 7717-26. PMID 23341451 DOI: 10.1074/Jbc.M112.424473 |
0.86 |
|
| 2013 |
Zhang S, Ye J, Zhang Y, Xu X, Liu J, Zhang SH, Kunapuli SP, Ding Z. P2Y12 protects platelets from apoptosis via PI3k-dependent Bak/Bax inactivation Journal of Thrombosis and Haemostasis. 11: 149-160. PMID 23140172 DOI: 10.1111/Jth.12063 |
0.607 |
|
| 2013 |
Zhang X, Szeto C, Gao E, Tang M, Jin J, Fu Q, Makarewich C, Ai X, Li Y, Tang A, Wang J, Gao H, Wang F, Ge XJ, Kunapuli SP, et al. Cardiotoxic and cardioprotective features of chronic β-adrenergic signaling. Circulation Research. 112: 498-509. PMID 23104882 DOI: 10.1161/Circresaha.112.273896 |
0.495 |
|
| 2013 |
Liverani E, Rico MC, Garcia AE, Kilpatrick LE, Kunapuli SP. Prasugrel metabolites inhibit neutrophil functions. The Journal of Pharmacology and Experimental Therapeutics. 344: 231-43. PMID 23097214 DOI: 10.1124/Jpet.112.195883 |
0.584 |
|
| 2013 |
Buitrago L, Tsygankov A, Sanjay A, Kunapuli SP. Cbl proteins in platelet activation. Platelets. 24: 419-27. PMID 22931288 DOI: 10.3109/09537104.2012.715216 |
0.561 |
|
| 2013 |
Abraham S, Dangelmaier CT, Zhou Y, Edelstein LC, Bray PF, Kunapuli SP, McKenzie SE. Syk Is Regulated Downstream Of FcγRIIA In Platelets By Transient Tyrosine Phosphorylation and Ubiquitylation Blood. 122: 4737-4737. DOI: 10.1182/Blood.V122.21.4737.4737 |
0.637 |
|
| 2013 |
Simon LM, Edelstein LC, Nagalla S, Bergeron A, Chen E, Kong X, Ma L, Kunapuli SP, Holinstat M, McKenzie SE, Dong J, Shaw C, F Bray P. Effect Of Age and Gender On Human Platelet mRNA and Micro-RNA Levels Blood. 122: 3518-3518. DOI: 10.1182/Blood.V122.21.3518.3518 |
0.353 |
|
| 2013 |
Pradhan S, Khatlani T, Kunapuli SP, Vijayan KV. Gβ1 a Component Of The Heterotrimeric G Protein Is a New Protein Phosphatase 1c Interacting Protein That Regulates Platelet Activation Blood. 122: 3508-3508. DOI: 10.1182/Blood.V122.21.3508.3508 |
0.591 |
|
| 2013 |
Liverani E, Rico MC, Tsygankov A, Kilpatrick LE, Kunapuli SP. Clopidogrel Modulates LPS-Induced Systemic Inflammation Through a P2Y12 receptor Independent Pathway Blood. 122: 2309-2309. DOI: 10.1182/Blood.V122.21.2309.2309 |
0.337 |
|
| 2013 |
Kim S, Dangelmaier C, Bhavanasi D, Meng S, Wang H, Goldfinger LE, Kunapuli SP. Rhog Regulates GPVI/FcRγ-Mediated Platelet Activation and Thrombus Formation Blood. 122: 1060-1060. DOI: 10.1182/Blood.V122.21.1060.1060 |
0.848 |
|
| 2012 |
Zhang Y, Ye J, Hu L, Zhang S, Zhang SH, Li Y, Kunapuli SP, Ding Z. Increased platelet activation and thrombosis in transgenic mice expressing constitutively active P2Y12 Journal of Thrombosis and Haemostasis. 10: 2149-2157. PMID 22906019 DOI: 10.1111/J.1538-7836.2012.04894.X |
0.612 |
|
| 2012 |
Bynagari-Settipalli YS, Lakhani P, Jin J, Bhavaraju K, Rico MC, Kim S, Woulfe D, Kunapuli SP. Protein kinase C isoform ε negatively regulates ADP-induced calcium mobilization and thromboxane generation in platelets. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 1211-9. PMID 22362759 DOI: 10.1161/Atvbaha.111.242388 |
0.842 |
|
| 2012 |
Rico MC, Rough JJ, Manns JM, Del Carpio-Cano F, Safadi FF, Kunapuli SP, DeLa Cadena RA. Assembly of the prothrombinase complex on the surface of human foreskin fibroblasts: Implications for connective tissue growth factor. Thrombosis Research. 129: 801-6. PMID 21889790 DOI: 10.1016/J.Thromres.2011.08.009 |
0.377 |
|
| 2012 |
Manne B, Getz TM, Hughes C, Dangelmaier CT, Watson SP, Kunapuli SP. Fucoidan Is a Novel Platelet Agonist for CLEC-2 Receptor Blood. 120: 94-94. DOI: 10.1182/Blood.V120.21.94.94 |
0.847 |
|
| 2012 |
Kunapuli SP, Kostyak JC. PKCδ Negatively Regulates Primary Megakaryocyte Proliferation and Differentiation Blood. 120: 853-853. DOI: 10.1182/Blood.V120.21.853.853 |
0.413 |
|
| 2012 |
Liverani E, Rico MC, Kilpatrick LE, Kunapuli SP. P2Y12 Null Mice Are Protected Against Sepsis-Induced Lung Injury Blood. 120: 615-615. DOI: 10.1182/Blood.V120.21.615.615 |
0.356 |
|
| 2012 |
Bhavanasi D, Dangelmaier CT, Jianguo J, Kim S, Kunapuli SP. Classical PKCs Regulate ADP-Induced Thromboxane Generation by Modulating Tyrosine Phosphorylation On Novel PKC Isoform Delta Through Shptp-1 Blood. 120: 1064-1064. DOI: 10.1182/Blood.V120.21.1064.1064 |
0.886 |
|
| 2011 |
Garcia AE, Mada SR, Rico MC, Dela Cadena RA, Kunapuli SP. Clopidogrel, a P2Y12 receptor antagonist, potentiates the inflammatory response in a rat model of peptidoglycan polysaccharide-induced arthritis. Plos One. 6: e26035. PMID 22028806 DOI: 10.1182/Blood.V118.21.3287.3287 |
0.455 |
|
| 2011 |
Buitrago L, Langdon WY, Sanjay A, Kunapuli SP. Tyrosine phosphorylated c-Cbl regulates platelet functional responses mediated by outside-in signaling. Blood. 118: 5631-40. PMID 21967979 DOI: 10.1182/Blood-2011-01-328807 |
0.577 |
|
| 2011 |
Hu L, Fan Z, Du H, Ni R, Zhang S, Yin K, Ye J, Zhang Y, Wei X, Zhang X, Gross PL, Kunapuli SP, Ding Z. BF061, a novel antiplatelet and antithrombotic agent targeting P2Yâ‚â‚‚ receptor and phosphodiesterase. Thrombosis and Haemostasis. 106: 1203-14. PMID 21946947 DOI: 10.1160/Th11-06-0400 |
0.541 |
|
| 2011 |
Bhavanasi D, Kim S, Goldfinger LE, Kunapuli SP. Protein kinase Cδ mediates the activation of protein kinase D2 in platelets. Biochemical Pharmacology. 82: 720-7. PMID 21736870 DOI: 10.1016/J.Bcp.2011.06.032 |
0.875 |
|
| 2011 |
Mayanglambam A, Bhavanasi D, Vijayan KV, Kunapuli SP. Differential dephosphorylation of the protein kinase C-zeta (PKCζ) in an integrin αIIbβ3-dependent manner in platelets. Biochemical Pharmacology. 82: 505-13. PMID 21645497 DOI: 10.1016/J.Bcp.2011.05.022 |
0.856 |
|
| 2011 |
Kim S, Kunapuli SP. Negative regulation of Gq-mediated pathways in platelets by G(12/13) pathways through Fyn kinase. The Journal of Biological Chemistry. 286: 24170-9. PMID 21592972 DOI: 10.1182/Blood.V112.11.2854.2854 |
0.599 |
|
| 2011 |
Bhavaraju K, Lakhani PR, Dorsam RT, Jin J, Hitchcock IS, Sanjay A, Kunapuli SP. G(12/13) signaling pathways substitute for integrin αIIbβ3-signaling for thromboxane generation in platelets. Plos One. 6: e16586. PMID 21347357 DOI: 10.1371/Journal.Pone.0016586 |
0.841 |
|
| 2011 |
Nagy B, Jin J, Ashby B, Reilly MP, Kunapuli SP. Contribution of the P2Y12 receptor-mediated pathway to platelet hyperreactivity in hypercholesterolemia. Journal of Thrombosis and Haemostasis : Jth. 9: 810-9. PMID 21261805 DOI: 10.1111/J.1538-7836.2011.04217.X |
0.577 |
|
| 2011 |
Getz TM, Mayanglambam A, Daniel JL, Kunapuli SP. Go6976 abrogates GPVI-mediated platelet functional responses in human platelets through inhibition of Syk. Journal of Thrombosis and Haemostasis : Jth. 9: 608-10. PMID 21251194 DOI: 10.1111/J.1538-7836.2011.04192.X |
0.879 |
|
| 2011 |
Kim S, Kunapuli SP. P2Y12 receptor in platelet activation. Platelets. 22: 56-60. PMID 21231822 DOI: 10.3109/09537104.2010.497231 |
0.561 |
|
| 2011 |
Turaga R, Bynagari YS, Nagy B, Kunapuli SP. Protein Kinase C isoforms -Implications to thrombosis Current Signal Transduction Therapy. 6: 353-362. DOI: 10.2174/157436211797484010 |
0.875 |
|
| 2011 |
Garcia AE, Rico MC, Liverani E, Kunapuli SP, De La Cadena RA. Prasugrel Aggravates the Inflammatory Response in a PG-PS-Induce Arthritis Model, Blood. 118: 3268-3268. DOI: 10.1182/Blood.V118.21.3268.3268 |
0.373 |
|
| 2010 |
Bhavaraju K, Georgakis A, Jin J, Gartner TK, Tomiyama Y, Nurden A, Nurden P, Kunapuli SP. Antagonism of P2Y₁₂ reduces physiological thromboxane levels. Platelets. 21: 604-9. PMID 21067313 DOI: 10.3109/09537104.2010.511684 |
0.761 |
|
| 2010 |
Zhang S, Hu L, Du H, Guo Y, Zhang Y, Niu H, Jin J, Zhang J, Liu J, Zhang X, Kunapuli SP, Ding Z. BF0801, a novel adenine derivative, inhibits platelet activation via phosphodiesterase inhibition and P2Y12 antagonism. Thrombosis and Haemostasis. 104: 845-57. PMID 20806121 DOI: 10.1160/Th10-05-0285 |
0.579 |
|
| 2010 |
Bynagari-Settipalli YS, Chari R, Kilpatrick L, Kunapuli SP. Protein kinase C - possible therapeutic target to treat cardiovascular diseases. Cardiovascular & Hematological Disorders Drug Targets. 10: 292-308. PMID 20678065 DOI: 10.2174/187152910793743869 |
0.682 |
|
| 2010 |
Chen X, Ren L, Kim S, Carpino N, Daniel JL, Kunapuli SP, Tsygankov AY, Pei D. Determination of the substrate specificity of protein-tyrosine phosphatase TULA-2 and identification of Syk as a TULA-2 substrate. The Journal of Biological Chemistry. 285: 31268-76. PMID 20670933 DOI: 10.1074/Jbc.M110.114181 |
0.308 |
|
| 2010 |
Getz TM, Dangelmaier CA, Jin J, Daniel JL, Kunapuli SP. Differential phosphorylation of myosin light chain (Thr)18 and (Ser)19 and functional implications in platelets. Journal of Thrombosis and Haemostasis : Jth. 8: 2283-93. PMID 20670370 DOI: 10.1111/J.1538-7836.2010.04000.X |
0.769 |
|
| 2010 |
Mao Y, Zhang L, Jin J, Ashby B, Kunapuli SP. Mutational analysis of residues important for ligand interaction with the human P2Y(12) receptor. European Journal of Pharmacology. 644: 10-6. PMID 20599922 DOI: 10.1016/J.Ejphar.2010.06.023 |
0.612 |
|
| 2010 |
Bhavaraju K, Mayanglambam A, Rao AK, Kunapuli SP. P2Y(12) antagonists as antiplatelet agents - Recent developments. Current Opinion in Drug Discovery & Development. 13: 497-506. PMID 20597033 |
0.79 |
|
| 2010 |
Thomas DH, Getz TM, Newman TN, Dangelmaier CA, Carpino N, Kunapuli SP, Tsygankov AY, Daniel JL. A novel histidine tyrosine phosphatase, TULA-2, associates with Syk and negatively regulates GPVI signaling in platelets. Blood. 116: 2570-8. PMID 20585042 DOI: 10.1182/Blood-2010-02-268136 |
0.831 |
|
| 2010 |
Garcia A, Kim S, Bhavaraju K, Schoenwaelder SM, Kunapuli SP. Role of phosphoinositide 3-kinase beta in platelet aggregation and thromboxane A2 generation mediated by Gi signalling pathways. The Biochemical Journal. 429: 369-77. PMID 20441566 DOI: 10.1042/Bj20100166 |
0.872 |
|
| 2010 |
Daniel JL, Dangelmaier CA, Mada S, Buitrago L, Jin J, Langdon WY, Tsygankov AY, Kunapuli SP, Sanjay A. Cbl-b is a novel physiologic regulator of glycoprotein VI-dependent platelet activation. The Journal of Biological Chemistry. 285: 17282-91. PMID 20400514 DOI: 10.1074/Jbc.M109.080200 |
0.503 |
|
| 2010 |
Mayanglambam A, Dangelmaier CA, Thomas D, Damodar Reddy C, Daniel JL, Kunapuli SP. Curcumin inhibits GPVI-mediated platelet activation by interfering with the kinase activity of Syk and the subsequent activation of PLCgamma2. Platelets. 21: 211-20. PMID 20158382 DOI: 10.3109/09537100903528269 |
0.87 |
|
| 2010 |
Mao Y, Zhang M, Tuma RF, Kunapuli SP. Deficiency of PAR4 attenuates cerebral ischemia/reperfusion injury in mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 30: 1044-52. PMID 20087365 DOI: 10.1038/Jcbfm.2009.283 |
0.568 |
|
| 2010 |
Garcia AE, Mada S, Rico MC, De La Cadena RA, Kunapuli S. Clopidogrel, a P2Y12 Receptor Antagonist, Potentiates the Inflammatory Response In An Animal Model of Erosive Arthritis Blood. 116: 4721-4721. DOI: 10.1182/Blood.V116.21.4721.4721 |
0.378 |
|
| 2010 |
Bhavanasi D, Kim S, Goldfinger LE, Kunapuli SP. Protein Kinase C Delta Mediates the Activation of Protein Kinase D In Platelets Blood. 116: 2021-2021. DOI: 10.1182/Blood.V116.21.2021.2021 |
0.872 |
|
| 2010 |
Bynagari Y, Lakhani P, Bhavaraju K, Jin J, Rico MC, Kim S, Woulfe DS, Kunapuli SP. Protein Kinase C Isoform ε Negatively Regulates ADP-Induced Thromboxane Generation by Regulating cPLA2 Activation and Calcium Mobilization In Platelets Blood. 116: 2020-2020. DOI: 10.1182/Blood.V116.21.2020.2020 |
0.876 |
|
| 2010 |
Buitrago CL, Kunapuli SP, Sanjay A. C-Cbl-PI3K Interaction Is Important for Platelet Outside-In Signaling Blood. 116: 2014-2014. DOI: 10.1182/Blood.V116.21.2014.2014 |
0.592 |
|
| 2009 |
Schmaier AA, Zou Z, Kazlauskas A, Emert-Sedlak L, Fong KP, Neeves KB, Maloney SF, Diamond SL, Kunapuli SP, Ware J, Brass LF, Smithgall TE, Saksela K, Kahn ML. Molecular priming of Lyn by GPVI enables an immune receptor to adopt a hemostatic role. Proceedings of the National Academy of Sciences of the United States of America. 106: 21167-72. PMID 19940238 DOI: 10.1073/Pnas.0906436106 |
0.586 |
|
| 2009 |
Kim S, Mangin P, Dangelmaier C, Lillian R, Jackson SP, Daniel JL, Kunapuli SP. Role of phosphoinositide 3-kinase beta in glycoprotein VI-mediated Akt activation in platelets. The Journal of Biological Chemistry. 284: 33763-72. PMID 19700402 DOI: 10.1074/Jbc.M109.048553 |
0.681 |
|
| 2009 |
Kar K, Ibrar S, Nanda V, Getz TM, Kunapuli SP, Brodsky B. Aromatic interactions promote self-association of collagen triple-helical peptides to higher-order structures. Biochemistry. 48: 7959-68. PMID 19610672 DOI: 10.1021/Bi900496M |
0.737 |
|
| 2009 |
Chari R, Kim S, Murugappan S, Sanjay A, Daniel JL, Kunapuli SP. Lyn, PKC-delta, SHIP-1 interactions regulate GPVI-mediated platelet-dense granule secretion. Blood. 114: 3056-63. PMID 19587372 DOI: 10.1182/Blood-2008-11-188516 |
0.868 |
|
| 2009 |
Mao Y, Jin J, Daniel JL, Kunapuli SP. Regulation of plasmin-induced protease-activated receptor 4 activation in platelets. Platelets. 20: 191-8. PMID 19437337 DOI: 10.1080/09537100902803635 |
0.739 |
|
| 2009 |
Bynagari YS, Nagy B, Tuluc F, Bhavaraju K, Kim S, Vijayan KV, Kunapuli SP. Mechanism of activation and functional role of protein kinase Ceta in human platelets. The Journal of Biological Chemistry. 284: 13413-21. PMID 19286657 DOI: 10.1074/Jbc.M808970200 |
0.878 |
|
| 2009 |
Chari R, Getz T, Nagy B, Bhavaraju K, Mao Y, Bynagari YS, Murugappan S, Nakayama K, Kunapuli SP. Protein kinase C[delta] differentially regulates platelet functional responses. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 699-705. PMID 19213940 DOI: 10.1161/Atvbaha.109.184010 |
0.862 |
|
| 2009 |
Nagy B, Bhavaraju K, Getz T, Bynagari YS, Kim S, Kunapuli SP. Impaired activation of platelets lacking protein kinase C-theta isoform. Blood. 113: 2557-67. PMID 19164598 DOI: 10.1182/Blood-2008-07-169268 |
0.878 |
|
| 2009 |
Jin J, Mao Y, Thomas D, Kim S, Daniel JL, Kunapuli SP. RhoA downstream of G(q) and G(12/13) pathways regulates protease-activated receptor-mediated dense granule release in platelets. Biochemical Pharmacology. 77: 835-44. PMID 19073150 DOI: 10.1016/J.Bcp.2008.11.017 |
0.666 |
|
| 2009 |
Ding Z, Bynagari YS, Mada SR, Jakubowski JA, Kunapuli SP. Studies on the role of the extracellular cysteines and oligomeric structures of the P2Y12 receptor when interacting with antagonists. Journal of Thrombosis and Haemostasis : Jth. 7: 232-4. PMID 18983481 DOI: 10.1111/J.1538-7836.2008.03202.X |
0.799 |
|
| 2009 |
Murugappan S, Chari R, Palli VM, Jin J, Kunapuli SP. Differential regulation of threonine and tyrosine phosphorylations on protein kinase Cdelta by G-protein-mediated pathways in platelets. The Biochemical Journal. 417: 113-20. PMID 18652571 DOI: 10.1042/Bj20080235 |
0.796 |
|
| 2009 |
Mao Y, Getz TM, Jin J, Kunapuli SP. Coagulation Factor XIIa Activates Platelets and Is the Physiological Agonist of Protease-Activated Receptor 3. Blood. 114: 770-770. DOI: 10.1182/Blood.V114.22.770.770 |
0.868 |
|
| 2009 |
Bhavaraju K, Georgakis A, Jin J, Tomiyama Y, Nurden AT, Nurden P, Kunapuli SP. Antagonism of P2y12 Receptor Results in Severe Impairment of Serum Thromboxane Levels. Can We Manage Patients without Combination Therapy with Aspirin? Blood. 114: 4013-4013. DOI: 10.1182/Blood.V114.22.4013.4013 |
0.809 |
|
| 2009 |
Chari R, Bhavanasi D, Daniel J, Kunapuli SP. SHIP-1 Associates with Tyrosine Phosphorylated Protein Kinase C-Delta at 155 Residue. Blood. 114: 3004-3004. DOI: 10.1182/Blood.V114.22.3004.3004 |
0.838 |
|
| 2009 |
Kunapuli SP, Jin J. Role of PKCθ in collagen-related peptide-induced platelet activation Blood. 114: 491-492. DOI: 10.1182/Blood-2009-05-219022 |
0.518 |
|
| 2008 |
Kahner BN, Dorsam RT, Kim S, Shankar H, Kitamura D, Kunapuli SP. Hematopoietic lineage cell-specific protein-1 (HS1) regulates PAR-mediated ERK activation and thromboxane generation in platelets. Platelets. 19: 614-23. PMID 19012179 DOI: 10.1080/09537100802351057 |
0.876 |
|
| 2008 |
Bhavaraju K, Kim S, Daniel JL, Kunapuli SP. Evaluation of [3-(1-methyl-1H-indol-3-yl-methylene)-2-oxo-2, 3-dihydro-1H-indole-5-sulfonamide] (OXSI-2), as a Syk-selective inhibitor in platelets. European Journal of Pharmacology. 580: 285-90. PMID 18068154 DOI: 10.1016/J.Ejphar.2007.11.009 |
0.863 |
|
| 2008 |
Kahner BN, Dorsam RT, Kunapuli SP. Role of P2Y receptor subtypes in platelet-derived microparticle generation. Frontiers in Bioscience : a Journal and Virtual Library. 13: 433-9. PMID 17981558 DOI: 10.2741/2690 |
0.826 |
|
| 2008 |
Mao Y, Jin J, Kunapuli SP. Characterization of a new peptide agonist of the protease-activated receptor-1. Biochemical Pharmacology. 75: 438-47. PMID 17950254 DOI: 10.1016/J.Bcp.2007.09.002 |
0.685 |
|
| 2008 |
Bynagari YS, Nagy B, Bhavaraju K, Woulfe D, Kim S, Kunapuli SP. nPKC Epsilon Negatively Regulates Platelet Functional Responses Blood. 112: 2855-2855. DOI: 10.1182/Blood.V112.11.2855.2855 |
0.851 |
|
| 2008 |
Rico MC, Rough JJ, Manns JM, Kunapuli SP, Cadena RADL. Assembly of the Prothrombinase Complex on Human Fibroblast Surface Is Enhanced by TSP1 and Leads to CTGF Upregulation by a Different Mechanism from the One Used by FXa and Thrombin. Blood. 112: 2013-2013. DOI: 10.1182/Blood.V112.11.2013.2013 |
0.365 |
|
| 2008 |
Chari R, Getz T, Nagy B, Bhavaraju K, Mao Y, Bynagari YS, Murugappan S, Nakayama K, Daniel J, Kunapuli SP. Protein Kinase Cδ Differentially Regulates Platelet Functional Responses. Blood. 112: 1841-1841. DOI: 10.1182/Blood.V112.11.1841.1841 |
0.867 |
|
| 2007 |
Kim S, Garcia A, Jackson SP, Kunapuli SP. Insulin-like growth factor-1 regulates platelet activation through PI3-Kalpha isoform. Blood. 110: 4206-13. PMID 17827385 DOI: 10.1182/Blood-2007-03-080804 |
0.57 |
|
| 2007 |
Kahner BN, Dorsam RT, Mada SR, Kim S, Stalker TJ, Brass LF, Daniel JL, Kitamura D, Kunapuli SP. Hematopoietic lineage cell specific protein 1 (HS1) is a functionally important signaling molecule in platelet activation. Blood. 110: 2449-56. PMID 17579181 DOI: 10.1182/Blood-2006-11-056069 |
0.86 |
|
| 2007 |
Sun L, Mao G, Kunapuli SP, Dhanasekaran DN, Rao AK. Alternative splice variants of phospholipase C-beta2 are expressed in platelets: effect on Galphaq-dependent activation and localization. Platelets. 18: 217-23. PMID 17497434 DOI: 10.1080/09537100601016133 |
0.419 |
|
| 2007 |
Garcia A, Shankar H, Murugappan S, Kim S, Kunapuli SP. Regulation and functional consequences of ADP receptor-mediated ERK2 activation in platelets. The Biochemical Journal. 404: 299-308. PMID 17298299 DOI: 10.1042/Bj20061584 |
0.842 |
|
| 2007 |
Quinter PG, Dangelmaier CA, Quinton TM, Kunapuli SP, Daniel JL. Glycoprotein VI agonists have distinct dependences on the lipid raft environment. Journal of Thrombosis and Haemostasis : Jth. 5: 362-8. PMID 17096705 DOI: 10.1111/J.1538-7836.2007.02309.X |
0.412 |
|
| 2007 |
Bhavaraju K, Kim S, Kunapuli SP. Lyn and Fyn Kinases Positively Regulate Thromboxane Generation in Platelets. Blood. 110: 3656-3656. DOI: 10.1182/Blood.V110.11.3656.3656 |
0.878 |
|
| 2007 |
Getz TM, Bhavaraju K, Kunapuli SP. CPI-17 Contributes to Calcium-Independent ADP-Induced Platelet Shape Change through P2Y1-Gq-PKC Pathways. Blood. 110: 3644-3644. DOI: 10.1182/Blood.V110.11.3644.3644 |
0.881 |
|
| 2007 |
Mao Y, Jin J, Kunapuli SP. Protease-Activated Receptor 3 Negatively Regulates Plasmin-Mediated Protease-Activated Receptor 4 Activation in Platelets. Blood. 110: 3636-3636. DOI: 10.1182/Blood.V110.11.3636.3636 |
0.747 |
|
| 2007 |
Chari R, Kim S, Murugappan S, Daniel JL, Kunapuli SP. SHIP-1 Differentially Regulates Dense Granule Secretion in Platelets through Its Association with Protein Kinase C δ. Blood. 110: 3630-3630. DOI: 10.1182/Blood.V110.11.3630.3630 |
0.861 |
|
| 2007 |
Kunapuli SP. Is there a physiologically relevant experimental model system to study GP1b-mediated signaling in platelets? [7] Blood. 109: 848. DOI: 10.1182/Blood-2006-10-049106 |
0.463 |
|
| 2007 |
Dangelmaier C, Mada S, Jianguoi J, Kunapuli S, Daniel J. CBL-B: A PHYSIOLOGICALLY IMPORTANT SIGNALING MOLECULE FOR COLLAGEN-DEPENDENT ACTIVATION Journal of Thrombosis and Haemostasis. 5: O-S-075-O-S-075. DOI: 10.1111/J.1538-7836.2007.Tb00078.X |
0.319 |
|
| 2006 |
Meshki J, Tuluc F, Bredetean O, Garcia A, Kunapuli SP. Signaling pathways downstream of P2 receptors in human neutrophils. Purinergic Signalling. 2: 537-44. PMID 18404491 DOI: 10.1007/S11302-006-9007-1 |
0.821 |
|
| 2006 |
Shankar H, Kahner B, Kunapuli SP. G-protein dependent platelet signaling--perspectives for therapy. Current Drug Targets. 7: 1253-63. PMID 17073586 DOI: 10.2174/138945006778559166 |
0.73 |
|
| 2006 |
Kahner BN, Shankar H, Murugappan S, Prasad GL, Kunapuli SP. Nucleotide receptor signaling in platelets. Journal of Thrombosis and Haemostasis : Jth. 4: 2317-26. PMID 17059469 DOI: 10.1111/J.1538-7836.2006.02192.X |
0.84 |
|
| 2006 |
Jalagadugula G, Dhanasekaran DN, Kim S, Kunapuli SP, Rao AK. Early growth response transcription factor EGR-1 regulates Galphaq gene in megakaryocytic cells. Journal of Thrombosis and Haemostasis : Jth. 4: 2678-86. PMID 16995904 DOI: 10.1111/J.1538-7836.2006.02229.X |
0.355 |
|
| 2006 |
Kahner BN, Quinton TM, Langan S, Kunapuli SP. Do heterotrimeric G proteins redistribute upon G protein-coupled receptor stimulation in platelets? Platelets. 17: 397-404. PMID 16973501 DOI: 10.1080/09537100600757794 |
0.504 |
|
| 2006 |
Shankar H, Kahner BN, Prabhakar J, Lakhani P, Kim S, Kunapuli SP. G-protein-gated inwardly rectifying potassium channels regulate ADP-induced cPLA2 activity in platelets through Src family kinases. Blood. 108: 3027-34. PMID 16857990 DOI: 10.1182/Blood-2006-03-010330 |
0.77 |
|
| 2006 |
Shankar H, Garcia A, Prabhakar J, Kim S, Kunapuli SP. P2Y12 receptor-mediated potentiation of thrombin-induced thromboxane A2 generation in platelets occurs through regulation of Erk1/2 activation. Journal of Thrombosis and Haemostasis : Jth. 4: 638-47. PMID 16460446 DOI: 10.1111/J.1538-7836.2006.01789.X |
0.735 |
|
| 2006 |
Murugappa S, Kunapuli SP. The role of ADP receptors in platelet function. Frontiers in Bioscience : a Journal and Virtual Library. 11: 1977-86. PMID 16368572 DOI: 10.2741/1939 |
0.588 |
|
| 2006 |
Ding Z, Kim S, Kunapuli SP. Identification of a potent inverse agonist at a constitutively active mutant of human P2Y12 receptor. Molecular Pharmacology. 69: 338-45. PMID 16234484 DOI: 10.1182/Blood.V106.11.3942.3942 |
0.568 |
|
| 2006 |
Kim S, Jin J, Kunapuli SP. Relative contribution of G-protein-coupled pathways to protease-activated receptor-mediated Akt phosphorylation in platelets. Blood. 107: 947-54. PMID 16223779 DOI: 10.1182/Blood-2005-07-3040 |
0.56 |
|
| 2006 |
Mao G, Kunapuli SP, Rao AK. Regulation of Platelet PLC-β2 Expression by NF-κB: Studies in Human Platelet PLC-β2 Deficiency. Blood. 108: 699-699. DOI: 10.1182/Blood.V108.11.699.699 |
0.368 |
|
| 2006 |
Jalagadugula G, Danny DN, Soochong K, Kunapuli SP, Rao AK. Early Growth Response Factor EGR-1 Regulates Gαq Gene in Megakaryocytic Cells. Blood. 108: 1518-1518. DOI: 10.1182/Blood.V108.11.1518.1518 |
0.333 |
|
| 2006 |
Tuluc F, Meshki J, Kunapuli SP. Reply to letter to the Editor [2] International Immunopharmacology. 6: 510-511. DOI: 10.1016/j.intimp.2005.08.020 |
0.702 |
|
| 2005 |
Tuluc F, Bredetean O, Brailoiu E, Meshki J, Garcia A, Dun NJ, Kunapuli SP. The priming effect of extracellular UTP on human neutrophils: Role of calcium released from thapsigargin-sensitive intracellular stores. Purinergic Signalling. 1: 359-68. PMID 18404520 DOI: 10.1007/S11302-005-0039-8 |
0.815 |
|
| 2005 |
Bredeţean O, Tuluc F, Ciochină AD, Iacob G, Meshki J, Kunapuli SP. [Functional characteristics of nucleotide-receptors in human neutrophils]. Revista Medico-Chirurgicală̆ a Societă̆Ţ̜Ii De Medici Ş̧I Naturaliş̧Ti Din Iaş̧I. 109: 191-9. PMID 16607854 |
0.808 |
|
| 2005 |
Garcia A, Quinton TM, Dorsam RT, Kunapuli SP. Src family kinase-mediated and Erk-mediated thromboxane A2 generation are essential for VWF/GPIb-induced fibrinogen receptor activation in human platelets. Blood. 106: 3410-4. PMID 16020504 DOI: 10.1182/Blood-2005-05-1933 |
0.866 |
|
| 2005 |
Quinton TM, Kim S, Jin J, Kunapuli SP. Lipid rafts are required in Gαi signaling downstream of the P2Y12 receptor during ADP-mediated platelet activation Journal of Thrombosis and Haemostasis. 3: 1036-1041. PMID 15869601 DOI: 10.1111/J.1538-7836.2005.01325.X |
0.571 |
|
| 2005 |
Murugappan S, Shankar H, Bhamidipati S, Dorsam RT, Jin J, Kunapuli SP. Molecular mechanism and functional implications of thrombin-mediated tyrosine phosphorylation of PKCdelta in platelets. Blood. 106: 550-7. PMID 15811957 DOI: 10.1182/Blood-2004-12-4866 |
0.87 |
|
| 2005 |
Dangelmaier CA, Quinter PG, Jin J, Tsygankov AY, Kunapuli SP, Daniel JL. Rapid ubiquitination of Syk following GPVI activation in platelets. Blood. 105: 3918-24. PMID 15701717 DOI: 10.1182/Blood-2004-09-3689 |
0.604 |
|
| 2005 |
Dorsam RT, Kim S, Murugappan S, Rachoor S, Shankar H, Jin J, Kunapuli SP. Differential requirements for calcium and Src family kinases in platelet GPIIb/IIIa activation and thromboxane generation downstream of different G-protein pathways. Blood. 105: 2749-56. PMID 15546949 DOI: 10.1182/Blood-2004-07-2821 |
0.84 |
|
| 2005 |
Ding Z, Tuluc F, Bandivadekar KR, Zhang L, Jin J, Kunapuli SP. Arg333 and Arg334 in the COOH terminus of the human P2Y1 receptor are crucial for Gq coupling. American Journal of Physiology. Cell Physiology. 288: C559-67. PMID 15509659 DOI: 10.1152/Ajpcell.00401.2004 |
0.411 |
|
| 2005 |
Quinter PG, Quinton TM, Dangelmaier CA, Kunapuli SP, Daniel JL. Role of Lipid Rafts in GPVI Agonist-Induced Platelet Signaling. Blood. 106: 3576-3576. DOI: 10.1182/Blood.V106.11.3576.3576 |
0.61 |
|
| 2005 |
Garcia A, Shankar H, Kunapuli SP. Mechanism of Activation and Role of Extracellular Signal Regulated Kinase in ADP-Induced Thromboxane A2 Generation in Platelets. Blood. 106: 3567-3567. DOI: 10.1182/Blood.V106.11.3567.3567 |
0.756 |
|
| 2005 |
Shankar H, Kunapuli SP. Is the P2Y1 receptor a better target for antithrombotic drugs? Drug Discovery Today: Therapeutic Strategies. 2: 285-290. DOI: 10.1016/J.Ddstr.2005.08.003 |
0.731 |
|
| 2004 |
Murugappan S, Shankar H, Kunapuli SP. Platelet receptors for adenine nucleotides and thromboxane A2. Seminars in Thrombosis and Hemostasis. 30: 411-8. PMID 15354262 DOI: 10.1055/S-2004-833476 |
0.811 |
|
| 2004 |
Paul BZ, Jin J, Kunapuli SP. Preparation of mRNA and cDNA libraries from platelets and megakaryocytes. Methods in Molecular Biology (Clifton, N.J.). 273: 435-54. PMID 15308817 DOI: 10.1385/1-59259-783-1:435 |
0.818 |
|
| 2004 |
Tuluc F, Garcia A, Bredetean O, Meshki J, Kunapuli SP. Primary granule release from human neutrophils is potentiated by soluble fibrinogen through a mechanism depending on multiple intracellular signaling pathways. American Journal of Physiology. Cell Physiology. 287: C1264-72. PMID 15229106 DOI: 10.1152/Ajpcell.00177.2004 |
0.822 |
|
| 2004 |
Shankar H, Murugappan S, Kim S, Jin J, Ding Z, Wickman K, Kunapuli SP. Role of G protein-gated inwardly rectifying potassium channels in P2Y12 receptor-mediated platelet functional responses. Blood. 104: 1335-43. PMID 15142872 DOI: 10.1182/Blood-2004-01-0069 |
0.833 |
|
| 2004 |
Quinton TM, Murugappan S, Kim S, Jin J, Kunapuli SP. Different G protein-coupled signaling pathways are involved in alpha granule release from human platelets. Journal of Thrombosis and Haemostasis : Jth. 2: 978-84. PMID 15140134 DOI: 10.1111/J.1538-7836.2004.00741.X |
0.662 |
|
| 2004 |
Dorsam RT, Tuluc M, Kunapuli SP. Role of protease-activated and ADP receptor subtypes in thrombin generation on human platelets. Journal of Thrombosis and Haemostasis : Jth. 2: 804-12. PMID 15099288 DOI: 10.1111/J.1538-7836.2004.00692.X |
0.836 |
|
| 2004 |
Quinton TM, Kim S, Derian CK, Jin J, Kunapuli SP. Plasmin-mediated activation of platelets occurs by cleavage of protease-activated receptor 4. The Journal of Biological Chemistry. 279: 18434-9. PMID 14973136 DOI: 10.1074/Jbc.M401431200 |
0.617 |
|
| 2004 |
Dorsam RT, Kunapuli SP. Central role of the P2Y12 receptor in platelet activation. The Journal of Clinical Investigation. 113: 340-5. PMID 14755328 DOI: 10.1172/Jci20986 |
0.83 |
|
| 2004 |
Kim S, Jin J, Kunapuli SP. Akt activation in platelets depends on Gi signaling pathways. The Journal of Biological Chemistry. 279: 4186-95. PMID 14623889 DOI: 10.1074/Jbc.M306162200 |
0.668 |
|
| 2004 |
Meshki J, Tuluc F, Bredetean O, Ding Z, Kunapuli SP. Molecular mechanism of nucleotide-induced primary granule release in human neutrophils: role for the P2Y2 receptor. American Journal of Physiology. Cell Physiology. 286: C264-71. PMID 14613890 DOI: 10.1152/Ajpcell.00287.2003 |
0.816 |
|
| 2004 |
Murugappan S, Tuluc F, Dorsam RT, Shankar H, Kunapuli SP. Differential role of protein kinase C delta isoform in agonist-induced dense granule secretion in human platelets. The Journal of Biological Chemistry. 279: 2360-7. PMID 14578358 DOI: 10.1074/Jbc.M306960200 |
0.886 |
|
| 2004 |
Dangelmaier CA, Quinter P, Jin J, Tysgankov AY, Kunapuli SP, Daniel JL. Regulation of Syk Function by Ubiquitination in Human Platelets. Blood. 104: 627-627. DOI: 10.1182/Blood.V104.11.627.627 |
0.601 |
|
| 2004 |
Kahner BN, Dorsam RT, Kunapuli SP. Both Platelet ADP Receptors Contribute to Microparticle Formation. Blood. 104: 3876-3876. DOI: 10.1182/Blood.V104.11.3876.3876 |
0.832 |
|
| 2004 |
Tuluc F, Rahim RT, Kunapuli SP. A Novel Receptor for N-Arachidonoyl Dopamine Mediates Intracellular Signaling Events in Human T-Cells. Blood. 104: 3861-3861. DOI: 10.1182/Blood.V104.11.3861.3861 |
0.432 |
|
| 2004 |
Garcia AE, Tuluc F, Meshki J, Bredetean O, Kunapuli SP. Extracellular Nucleotide UTP Regulate Lipopolisaccharide-Induced Cytokine Production in Human Neutrophils. Blood. 104: 3791-3791. DOI: 10.1182/Blood.V104.11.3791.3791 |
0.784 |
|
| 2004 |
Murugappan S, Shankar H, Kunapuli S. Thrombin Mediated Tyrosine Phosphorylation of PKCδ in Human Platelets Occurs in a Calcium- and Src Family Tyrosine Kinase- Dependent Manner. Blood. 104: 3541-3541. DOI: 10.1182/Blood.V104.11.3541.3541 |
0.836 |
|
| 2004 |
Kim S, Jin J, Kunapuli SP. G12/13 Pathways Potentiate Akt Phosphorylation in Platelets Mediated by Gi/Gz Pathways in a Src Kinase-Dependent Manner. Blood. 104: 1570-1570. DOI: 10.1182/Blood.V104.11.1570.1570 |
0.618 |
|
| 2004 |
Ding Z, Tuluc F, Bandivadekar KR, Zhang L, Jin J, Kunapuli SP. Arg333 and Arg334 in the C-Terminus of the Human Platelet P2Y1 Receptor Are Crucial for Gq Coupling. Blood. 104: 1566-1566. DOI: 10.1182/Blood.V104.11.1566.1566 |
0.538 |
|
| 2004 |
Shankar H, Prabhakar J, Lakhani P, Kunapuli SP. Role of G-Protein Coupled Inwardly Rectifying Potassium (GIRK) Channels in ADP-Mediated Thromboxane A2 Generation. Blood. 104: 1565-1565. DOI: 10.1182/Blood.V104.11.1565.1565 |
0.759 |
|
| 2004 |
Jin J, Kim S, Kunapuli S. Activation of G12/13 Pathway Is Essential for the Dense Granule Release in Platelets. Blood. 104: 1564-1564. DOI: 10.1182/Blood.V104.11.1564.1564 |
0.567 |
|
| 2003 |
Dorsam RT, Murugappan S, Ding Z, Kunapuli SP. Clopidogrel: interactions with the P2Y12 receptor and clinical relevance. Hematology (Amsterdam, Netherlands). 8: 359-65. PMID 14668029 DOI: 10.1080/10245330310001621260 |
0.789 |
|
| 2003 |
Tuluc F, Meshki J, Kunapuli SP. Membrane lipid microdomains differentially regulate intracellular signaling events in human neutrophils. International Immunopharmacology. 3: 1775-90. PMID 14636828 DOI: 10.1016/J.Intimp.2003.08.002 |
0.81 |
|
| 2003 |
Kunapuli SP, Ding Z, Dorsam RT, Kim S, Murugappan S, Quinton TM. ADP receptors--targets for developing antithrombotic agents. Current Pharmaceutical Design. 9: 2303-16. PMID 14529392 DOI: 10.2174/1381612033453947 |
0.865 |
|
| 2003 |
Paul BZ, Vilaire G, Kunapuli SP, Bennett JS. Concurrent signaling from Galphaq- and Galphai-coupled pathways is essential for agonist-induced alphavbeta3 activation on human platelets. Journal of Thrombosis and Haemostasis : Jth. 1: 814-20. PMID 12871420 DOI: 10.1046/J.1538-7836.2003.00099.X |
0.879 |
|
| 2003 |
Paul BZ, Kim S, Dangelmaier C, Nagaswami C, Jin J, Hartwig JH, Weisel JW, Daniel JL, Kunapuli SP. Dynamic regulation of microtubule coils in ADP-induced platelet shape change by p160ROCK (Rho-kinase). Platelets. 14: 159-69. PMID 12850840 DOI: 10.1080/0953710031000092794 |
0.832 |
|
| 2003 |
Kunapuli SP, Dorsam RT, Kim S, Quinton TM. Platelet purinergic receptors. Current Opinion in Pharmacology. 3: 175-80. PMID 12681240 DOI: 10.1016/S1471-4892(03)00007-9 |
0.834 |
|
| 2003 |
Ding Z, Kim S, Dorsam RT, Jin J, Kunapuli SP. Inactivation of the human P2Y12 receptor by thiol reagents requires interaction with both extracellular cysteine residues, Cys17 and Cys270. Blood. 101: 3908-14. PMID 12560222 DOI: 10.1182/Blood-2002-10-3027 |
0.79 |
|
| 2003 |
Jin J, Tuluc M, Kunapuli S. Human platelets generate thromboxane A2 upon interaction with immobilized fibrinogen without a requirement for adherence in a Syk-dependent manner Journal of Thrombosis and Haemostasis. 1: P0719-P0719. DOI: 10.1111/j.1538-7836.2003.tb04354.x |
0.334 |
|
| 2002 |
Kunapuli SP. P2 receptors and platelet activation Thescientificworldjournal [Electronic Resource]. 2: 424-433. PMID 12806027 |
0.475 |
|
| 2002 |
Ozdener F, Kunapuli SP, Daniel JL. Expression of enzymatically-active phospholipase Cgamma2 in E. coli. Journal of Biochemistry and Molecular Biology. 35: 508-12. PMID 12359094 DOI: 10.5483/Bmbrep.2002.35.5.508 |
0.323 |
|
| 2002 |
Dorsam RT, Kim S, Jin J, Kunapuli SP. Coordinated signaling through both G12/13 and G(i) pathways is sufficient to activate GPIIb/IIIa in human platelets. The Journal of Biological Chemistry. 277: 47588-95. PMID 12297512 DOI: 10.1074/Jbc.M208778200 |
0.789 |
|
| 2002 |
Quinton TM, Kim S, Dangelmaier C, Dorsam RT, Jin J, Daniel JL, Kunapuli SP. Protein kinase C- and calcium-regulated pathways independently synergize with Gi pathways in agonist-induced fibrinogen receptor activation. The Biochemical Journal. 368: 535-43. PMID 12215172 DOI: 10.1042/Bj20020226 |
0.849 |
|
| 2002 |
Ozdener F, Dangelmaier C, Ashby B, Kunapuli SP, Daniel JL. Activation of phospholipase Cgamma2 by tyrosine phosphorylation. Molecular Pharmacology. 62: 672-9. PMID 12181444 DOI: 10.1124/Mol.62.3.672 |
0.505 |
|
| 2002 |
Cattaneo M, Gachet C, Cazenave JP, Packham MA, Jin J, Quinton TM, Zhang J, Rittenhouse SE, Kunapuli SP. Adenosine diphosphate (ADP) does not induce thromboxane A2 generation in human platelets [2] (multiple letters) Blood. 99: 3868-3870. PMID 12014368 DOI: 10.1182/blood-2002-01-0313 |
0.361 |
|
| 2002 |
Kim S, Foster C, Lecchi A, Quinton TM, Prosser DM, Jin J, Cattaneo M, Kunapuli SP. Protease-activated receptors 1 and 4 do not stimulate G(i) signaling pathways in the absence of secreted ADP and cause human platelet aggregation independently of G(i) signaling. Blood. 99: 3629-36. PMID 11986217 DOI: 10.1182/Blood.V99.10.3629 |
0.637 |
|
| 2002 |
Quinton TM, Ozdener F, Dangelmaier C, Daniel JL, Kunapuli SP. Glycoprotein VI-mediated platelet fibrinogen receptor activation occurs through calcium-sensitive and PKC-sensitive pathways without a requirement for secreted ADP. Blood. 99: 3228-34. PMID 11964287 DOI: 10.1182/Blood.V99.9.3228 |
0.668 |
|
| 2002 |
Mao GF, Vaidyula VR, Kunapuli SP, Rao AK. Lineage-specific defect in gene expression in human platelet phospholipase C-beta2 deficiency. Blood. 99: 905-11. PMID 11806993 DOI: 10.1182/Blood.V99.3.905 |
0.423 |
|
| 2002 |
Jin J, Quinton TM, Zhang J, Rittenhouse SE, Kunapuli SP. Adenosine diphosphate (ADP)-induced thromboxane A(2) generation in human platelets requires coordinated signaling through integrin alpha(IIb)beta(3) and ADP receptors. Blood. 99: 193-8. PMID 11756171 DOI: 10.1182/Blood.V99.1.193 |
0.625 |
|
| 2001 |
Jin J, Tomlinson W, Kirk IP, Kim YB, Humphries RG, Kunapuli SP. The C6-2B glioma cell P2Y AC receptor is pharmacologically and molecularly identical to the platelet P2Y 12 receptor British Journal of Pharmacology. 133: 521-528. PMID 11399669 DOI: 10.1038/Sj.Bjp.0704114 |
0.547 |
|
| 2001 |
Ozdener F, Kunapuli SP, Daniel JL. Carboxyl terminal sequence of human phospholipase Cgamma2. Platelets. 12: 121-3. PMID 11297033 DOI: 10.1080/09537100020032864 |
0.419 |
|
| 2001 |
Dangelmaier C, Jin J, Smith JB, Kunapuli SP. Potentiation of thromboxane A2-induced platelet secretion by Gi signaling through the phosphoinositide-3 kinase pathway Thrombosis and Haemostasis. 85: 341-348. PMID 11246558 DOI: 10.1055/S-0037-1615690 |
0.659 |
|
| 2000 |
Mao GF, Kunapuli SP, Koneti Rao A. Evidence for two alternatively spliced forms of phospholipase C-beta2 in haematopoietic cells. British Journal of Haematology. 110: 402-8. PMID 10971398 DOI: 10.1046/J.1365-2141.2000.02201.X |
0.311 |
|
| 2000 |
Dasari VR, Jin J, Kunapuli SP. Distribution of leukotriene B4 receptors in human hematopoietic cells Immunopharmacology. 48: 157-163. PMID 10936513 DOI: 10.1016/S0162-3109(00)00201-0 |
0.424 |
|
| 2000 |
Dangelmaier C, Jin J, Daniel JL, Smith JB, Kunapuli SP. The P2Y1 receptor mediates ADP-induced p38 kinase-activating factor generation in human platelets. European Journal of Biochemistry / Febs. 267: 2283-9. PMID 10759852 DOI: 10.1046/J.1432-1327.2000.01235.X |
0.611 |
|
| 2000 |
Kowalska MA, Ratajczak MZ, Majka M, Jin J, Kunapuli S, Brass L, Poncz M. Stromal cell–derived factor-1 and macrophage-derived chemokine: 2 chemokines that activate platelets Blood. 96: 50-57. DOI: 10.1182/Blood.V96.1.50.013K40_50_57 |
0.637 |
|
| 2000 |
Kowalska MA, Ratajczak MZ, Majka M, Jin J, Kunapuli S, Brass L, Poncz M. Stromal cell–derived factor-1 and macrophage-derived chemokine: 2 chemokines that activate platelets Blood. 96: 50-57. DOI: 10.1182/blood.V96.1.50.013k40_50_57 |
0.565 |
|
| 2000 |
Quinton TM, Kunapuli SP. Detection of fibrinogen receptor activation during reversible aggregation of human platelets Blood. 96. |
0.53 |
|
| 2000 |
Ozdener F, Quinten TM, Kunapuli SP. Molecular mechanism of glycoprotein VI-mediated platelet activation Blood. 96. |
0.604 |
|
| 2000 |
Kirn S, Quinton TM, Jin J, Cattaneo M, Kunapuli SP. Evidence for diverse signal transduction pathways in thrombin receptor activating peptide (sfllrn) and other agonist-induced fibrinogen receptor activation in human platelets Blood. 96. |
0.601 |
|
| 2000 |
Ozdener F, Dangelmaier C, Ashby B, Kunapuli SP, Daniel JL. Activation of PLCy2 by tyrosine phosphorylation Blood. 96: 246a-247a. |
0.324 |
|
| 2000 |
Quinton TM, Dangelmaier C, Dorsam RT, Jin J, Daniel JL, Kunapuli SP. Calcium-sensitive and protein kinase C-sensitive pathways independently mediate agonist-induced fibrinogen receptor activation in human platelets Blood. 96: 247a. |
0.827 |
|
| 1999 |
Kim YB, Jin J, Dangelmaier C, Daniel JL, Kunapuli SP. The P2Y1 receptor is essential for ADP-induced shape change and aggregation in mouse platelets. Platelets. 10: 399-406. PMID 16801119 DOI: 10.1080/09537109975870 |
0.606 |
|
| 1999 |
Daniel JL, Dangelmaier C, Jin J, Kim YB, Kunapuli SP. Role of intracellular signaling events in ADP-induced platelet aggregation. Thrombosis and Haemostasis. 82: 1322-6. PMID 10544922 DOI: 10.1055/S-0037-1614384 |
0.663 |
|
| 1999 |
Paul BZ, Jin J, Kunapuli SP. Molecular mechanism of thromboxane A(2)-induced platelet aggregation. Essential role for p2t(ac) and alpha(2a) receptors. The Journal of Biological Chemistry. 274: 29108-14. PMID 10506165 DOI: 10.1074/Jbc.274.41.29108 |
0.869 |
|
| 1999 |
Paul BZ, Daniel JL, Kunapuli SP. Platelet shape change is mediated by both calcium-dependent and -independent signaling pathways. Role of p160 Rho-associated coiled-coil-containing protein kinase in platelet shape change. The Journal of Biological Chemistry. 274: 28293-300. PMID 10497186 DOI: 10.1074/Jbc.274.40.28293 |
0.853 |
|
| 1999 |
Kunapuli SP. Molecular events in ADP-induced platelet shape change Drug News and Perspectives. 12: 524-528. DOI: 10.1358/Dnp.1999.12.9.863633 |
0.604 |
|
| 1998 |
Kunapuli SP, Daniel JL. P2 receptor subtypes in the cardiovascular system. The Biochemical Journal. 336: 513-23. PMID 9841859 DOI: 10.1042/Bj3360513 |
0.474 |
|
| 1998 |
Kunapuli SP. Multiple P2 receptor subtypes on platelets: A new interpretation of their function Trends in Pharmacological Sciences. 19: 391-394. PMID 9803826 DOI: 10.1016/S0165-6147(98)01248-6 |
0.492 |
|
| 1998 |
Singh SP, Gao Y, Singh LD, Kunapuli SP, Ravindra R. Role of microtubules in glucose uptake by C6 glioma cells Pharmacology and Toxicology. 83: 83-89. PMID 9783325 DOI: 10.1111/J.1600-0773.1998.Tb01448.X |
0.305 |
|
| 1998 |
Jin J, Kunapuli SP. Coactivation of two different G protein-coupled receptors is essential for ADP-induced platelet aggregation Proceedings of the National Academy of Sciences of the United States of America. 95: 8070-8074. PMID 9653141 DOI: 10.1073/Pnas.95.14.8070 |
0.594 |
|
| 1998 |
Jin J, Dasari VR, Sistare FD, Kunapuli SP. Distribution of P2Y receptor subtypes on haematopoietic cells British Journal of Pharmacology. 123: 789-794. PMID 9535005 DOI: 10.1038/Sj.Bjp.0701665 |
0.404 |
|
| 1998 |
DeLa Cadena RA, Kunapuli SP, Walz DA, Colman RW. Expression of thrombospondin 1 on the surface of activated platelets mediates their interaction with the heavy chains of human kininogens through Lys 244-Pro 254 Thrombosis and Haemostasis. 79: 186-194. PMID 9459346 DOI: 10.1055/S-0037-1614248 |
0.505 |
|
| 1998 |
Jin J, Daniel JL, Kunapuli SP. Molecular basis for ADP-induced platelet activation. II. The P2Y1 receptor mediates ADP-induced intracellular calcium mobilization and shape change in platelets. The Journal of Biological Chemistry. 273: 2030-4. PMID 9442040 DOI: 10.1074/Jbc.273.4.2030 |
0.606 |
|
| 1998 |
Daniel JL, Dangelmaier C, Jin J, Ashby B, Smith JB, Kunapuli SP. Molecular basis for ADP-induced platelet activation. I. Evidence for three distinct ADP receptors on human platelets. The Journal of Biological Chemistry. 273: 2024-9. PMID 9442039 DOI: 10.1074/Jbc.273.4.2024 |
0.593 |
|
| 1998 |
Kunapuli SP. Functional characterization of platelet ADP receptors Platelets. 9: 343-351. DOI: 10.1080/09537109876401 |
0.568 |
|
| 1998 |
Kunapuli SP. Molecular physiology of platelet ADP receptors Drug Development Research. 45: 135-139. DOI: 10.1002/(Sici)1098-2299(199811/12)45:3/4<135::Aid-Ddr8>3.0.Co;2-B |
0.561 |
|
| 1998 |
Kunapuli SP, Jin J. Concomitant signaling from two different G protein-coupled receptors is essential for ADP-induced platelet aggregation Faseb Journal. 12. |
0.528 |
|
| 1997 |
Pidlaoan LV, Jin J, Sandhu AK, Athwal RS, Kunapuli SP. Colocalization of P2Y2 and P2Y6 receptor genes at human chromosome 11q13.3-14.1. Somatic Cell and Molecular Genetics. 23: 291-6. PMID 9542531 DOI: 10.1007/Bf02674420 |
0.309 |
|
| 1997 |
Parekh H, Pillarisetti K, Kunapuli S, Simpkins H. Isolation of a hamster cDNA homologous to the mouse and human cyclin kinase inhibitory protein p27Kip1. Somatic Cell and Molecular Genetics. 23: 147-51. PMID 9330642 DOI: 10.1007/Bf02679973 |
0.359 |
|
| 1997 |
Bradford HN, Dela Cadena RA, Kunapuli SP, Dong JF, Löpez JA, Colman RW. Human kininogens regulate thrombin binding to platelets through the glycoprotein Ib-IX-V complex. Blood. 90: 1508-15. PMID 9269768 DOI: 10.1182/Blood.V90.4.1508.1508_1508_1515 |
0.538 |
|
| 1997 |
Akbar GKM, Mills DCB, Kunapuli SP. Characterization of extracellular nucleotide-induced Mac-1 (α(M)β2 integrin) surface expression on peripheral blood leukocytes Biochemical and Biophysical Research Communications. 233: 71-75. PMID 9144398 DOI: 10.1006/Bbrc.1997.6396 |
0.425 |
|
| 1997 |
Kunapuli SP, Dasari V, Jin J, Sistare FD. Distribution of P2Y purinoceptors on hematopoietic cells Faseb Journal. 11. |
0.33 |
|
| 1996 |
Akbar GK, Dasari VR, Sheth SB, Ashby B, Mills DC, Kunapuli SP. Characterization of P2 purinergic receptors on human erythro leukemia cells. Journal of Receptor and Signal Transduction Research. 16: 209-24. PMID 8897312 DOI: 10.3109/10799899609039949 |
0.409 |
|
| 1996 |
Colman RW, Bradford HN, Kunapuli SP, DeLa Cadena RA, Rick L, Jameson BA, Wassell RP. Leu271-Glu292 in kininogens blocks thrombin-induced aggregation. Immunopharmacology. 32: 80-1. PMID 8796272 DOI: 10.1016/0162-3109(95)00056-9 |
0.486 |
|
| 1996 |
Akbar GK, Dasari VR, Webb TE, Ayyanathan K, Pillarisetti K, Sandhu AK, Athwal RS, Daniel JL, Ashby B, Barnard EA, Kunapuli SP. Molecular cloning of a novel P2 purinoceptor from human erythroleukemia cells. The Journal of Biological Chemistry. 271: 18363-7. PMID 8702478 DOI: 10.1074/Jbc.271.31.18363 |
0.378 |
|
| 1996 |
Kunapuli SP, Bradford HN, Jameson BA, DeLa Cadena RA, Rick L, Wassell RP, Colman RW. Thrombin-induced platelet aggregation is inhibited by the heptapeptide Leu271-Ala277 of domain 3 in the heavy chain of high molecular weight kininogen. The Journal of Biological Chemistry. 271: 11228-35. PMID 8626672 DOI: 10.1074/Jbc.271.19.11228 |
0.56 |
|
| 1995 |
Zhu J, Chen C, Xue JC, Kunapuli S, DeRiel JK, Liu-Chen LY. Cloning of a human kappa opioid receptor from the brain. Life Sciences. 56: PL201-7. PMID 7869844 DOI: 10.1016/0024-3205(94)00507-O |
0.304 |
|
| 1994 |
Kunapuli SP, Fen Mao G, Bastepe M, Liu-Chen LY, Li S, Cheung PP, DeRiel JK, Ashby B. Cloning and expression of a prostaglandin E receptor EP3 subtype from human erythroleukaemia cells. The Biochemical Journal. 298: 263-7. PMID 8135729 DOI: 10.1042/Bj2980263 |
0.464 |
|
| 1994 |
Sinha D, Bakhshi M, Kunapuli S, Vora R, Gabriel JL, Kirby EP, Budzynski AZ. ASP514 within the A1 domain of bovine von Willebrand factor is required for interaction with platelet glycoprotein Ib. Biochemical and Biophysical Research Communications. 203: 881-8. PMID 8093071 DOI: 10.1006/Bbrc.1994.2265 |
0.506 |
|
| 1994 |
DeLa Cadena RA, Wyshock EG, Kunapuli SP, Schultze RL, Miller M, Walz DA, Colman RW. Platelet thrombospondin interactions with human high and low molecular weight kininogens Thrombosis and Haemostasis. 72: 125-131. PMID 7974360 DOI: 10.1055/S-0038-1648823 |
0.357 |
|
| 1993 |
Kunapuli SP, Colman RW. Platelet-kininogen interactions Platelets. 4: 61-65. DOI: 10.3109/09537109309013197 |
0.476 |
|
| 1992 |
Kunapuli SP, DeLa Cadena RA, Colman RW. Bacterial expression of biologically active high molecular weight kininogen light chain Thrombosis and Haemostasis. 67: 428-433. PMID 1631790 DOI: 10.1055/S-0038-1648465 |
0.32 |
|
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