| Year |
Citation |
Score |
| 2022 |
Hines MR, Goetz JE, Gomez-Contreras PC, Rodman SN, Liman S, Femino EL, Kluz PN, Wagner BA, Buettner GR, Kelley EE, Coleman MC. Extracellular biomolecular free radical formation during injury. Free Radical Biology & Medicine. PMID 35724853 DOI: 10.1016/j.freeradbiomed.2022.06.223 |
0.557 |
|
| 2021 |
Stolwijk JM, Stefely JA, Veling MT, van 't Erve TJ, Wagner BA, Raife TJ, Buettner GR. Red blood cells contain enzymatically active GPx4 whose abundance anticorrelates with hemolysis during blood bank storage. Redox Biology. 46: 102073. PMID 34298465 DOI: 10.1016/j.redox.2021.102073 |
0.75 |
|
| 2020 |
Erudaitius DT, Buettner GR, Rodgers VGJ. The latency of peroxisomal catalase in terms of effectiveness factor for pancreatic and glioblastoma cancer cell lines in the presence of high concentrations of HO: Implications for the use of pharmacological ascorbate in cancer therapy. Free Radical Biology & Medicine. 156: 20-25. PMID 32522584 DOI: 10.1016/J.Freeradbiomed.2020.05.023 |
0.374 |
|
| 2020 |
Stolwijk JM, Garje R, Sieren JC, Buettner GR, Zakharia Y. Understanding the Redox Biology of Selenium in the Search of Targeted Cancer Therapies. Antioxidants (Basel, Switzerland). 9. PMID 32414091 DOI: 10.3390/Antiox9050420 |
0.393 |
|
| 2020 |
Stolwijk JM, Falls-Hubert KC, Searby CC, Wagner BA, Buettner GR. Simultaneous detection of the enzyme activities of GPx1 and GPx4 guide optimization of selenium in cell biological experiments. Redox Biology. 32: 101518. PMID 32278283 DOI: 10.1016/J.Redox.2020.101518 |
0.345 |
|
| 2020 |
Gibson AR, O'Leary BR, Du J, Sarsour EH, Kalen AL, Wagner BA, Stolwijk JM, Falls-Hubert KC, Alexander MS, Carroll RS, Spitz DR, Buettner GR, Goswami PC, Cullen JJ. Dual Oxidase-Induced Sustained Generation of Hydrogen Peroxide Contributes to Pharmacological Ascorbate-Induced Cytotoxicity. Cancer Research. PMID 32041838 DOI: 10.1158/0008-5472.Can-19-3094 |
0.384 |
|
| 2020 |
Falls-Hubert KC, Butler AL, Gui K, Anderson M, Li M, Stolwijk JM, Rodman SN, Solst SR, Tomanek-Chalkley A, Searby CC, Sheffield VC, Sandfort V, Schmidt H, McCormick M, Wels BR, ... ... Buettner GR, et al. Disulfiram causes selective hypoxic cancer cell toxicity and radio-chemo-sensitization via redox cycling of copper. Free Radical Biology & Medicine. PMID 32032663 DOI: 10.1016/J.Freeradbiomed.2020.01.186 |
0.361 |
|
| 2020 |
Kalen AL, Wagner BA, Sarsour EH, Kumar MG, Reedy JL, Buettner GR, Barua NC, Goswami PC. Hydrogen Peroxide Mediates Artemisinin-Derived C-16 Carba-Dimer-Induced Toxicity of Human Cancer Cells. Antioxidants (Basel, Switzerland). 9. PMID 31991904 DOI: 10.3390/Antiox9020108 |
0.372 |
|
| 2019 |
Musser ML, Mahaffey AL, Fath MA, Buettner GR, Wagner BA, Schneider BK, Seo YJ, Mochel JP, Johannes CM. Cytotoxicity and Pharmacokinetic Evaluation of Pharmacological Ascorbate in Dogs. Frontiers in Veterinary Science. 6: 385. PMID 31788483 DOI: 10.3389/Fvets.2019.00385 |
0.334 |
|
| 2019 |
Bi J, Yang S, Li L, Dai Q, Borcherding N, Wagner BA, Buettner GR, Spitz DR, Leslie KK, Zhang J, Meng X. Metadherin enhances vulnerability of cancer cells to ferroptosis. Cell Death & Disease. 10: 682. PMID 31527591 DOI: 10.1038/S41419-019-1897-2 |
0.353 |
|
| 2019 |
Petronek MS, Spitz DR, Buettner GR, Allen BG. Linking Cancer Metabolic Dysfunction and Genetic Instability through the Lens of Iron Metabolism. Cancers. 11. PMID 31366108 DOI: 10.3390/Cancers11081077 |
0.322 |
|
| 2019 |
Buranasudja V, Doskey CM, Gibson AR, Wagner BA, Du J, Gordon DJ, Koppenhafer SL, Cullen JJ, Buettner GR. Pharmacological Ascorbate Primes Pancreatic Cancer Cells for Death by Rewiring Cellular Energetics and Inducing DNA Damage. Molecular Cancer Research : McR. PMID 31337671 DOI: 10.1158/1541-7786.Mcr-19-0381 |
0.746 |
|
| 2019 |
Lafin JT, Sarsour EH, Kalen AL, Wagner BA, Buettner GR, Goswami PC. Methylseleninic Acid Induces Lipid Peroxidation and Radiation Sensitivity in Head and Neck Cancer Cells. International Journal of Molecular Sciences. 20. PMID 30626124 DOI: 10.3390/Ijms20010225 |
0.377 |
|
| 2019 |
Schoenfeld JD, Alexander MS, Waldron TJ, Sibenaller ZA, Spitz DR, Buettner GR, Allen BG, Cullen JJ. Pharmacological Ascorbate as a Means of Sensitizing Cancer Cells to Radio-Chemotherapy While Protecting Normal Tissue. Seminars in Radiation Oncology. 29: 25-32. PMID 30573181 DOI: 10.1016/J.Semradonc.2018.10.006 |
0.362 |
|
| 2018 |
Alexander MS, O'Leary BR, Wilkes JG, Gibson AR, Wagner BA, Du J, Sarsour E, Hwang RF, Buettner GR, Cullen JJ. Enhanced Pharmacological Ascorbate Oxidation Radiosensitizes Pancreatic Cancer. Radiation Research. PMID 30376411 DOI: 10.1667/Rr15189.1 |
0.368 |
|
| 2018 |
Alexander MS, Wilkes JG, Schroeder SR, Buettner GR, Wagner BA, Du J, Gibson-Corely K, O'Leary BR, Spitz DR, Buatti JM, Berg DJ, Bodeker KL, Vollstedt S, Brown HA, Allen BG, et al. Pharmacological ascorbate reduces radiation-induced normal tissue toxicity and enhances tumor radiosensitization in pancreatic cancer. Cancer Research. PMID 30254147 DOI: 10.1158/0008-5472.Can-18-1680 |
0.339 |
|
| 2018 |
Wert KJ, Velez G, Cross MR, Wagner BA, Teoh-Fitzgerald ML, Buettner GR, McAnany J, Olivier A, Tsang SH, Harper MM, Domann FE, Bassuk AG, Mahajan VB. Extracellular superoxide dismutase 3 (SOD3) regulates oxidative stress at the vitreoretinal interface. Free Radical Biology & Medicine. PMID 29940351 DOI: 10.1016/J.Freeradbiomed.2018.06.024 |
0.313 |
|
| 2018 |
Brandt KE, Falls KC, Schoenfeld JD, Rodman SN, Gu Z, Zhan F, Cullen JJ, Wagner BA, Buettner GR, Allen BG, Berg DJ, Spitz DR, Fath MA. Corrigendum to: Augmentation of intracellular iron using iron sucrose enhances the toxicity of pharmacological ascorbate in colon cancer cells [Redox Biol. (2018) 82-87]. Redox Biology. PMID 29891355 DOI: 10.1016/J.Redox.2018.06.001 |
0.305 |
|
| 2018 |
Erudaitius D, Mantooth J, Huang A, Soliman J, Doskey C, Buettner GR, Rodgers VGJ. Calculated Cell-Specific Intracellular Hydrogen Peroxide Concentration: Relevance in Cancer Cell Susceptibility during Ascorbate Therapy. Free Radical Biology & Medicine. PMID 29601946 DOI: 10.1016/J.Freeradbiomed.2018.03.044 |
0.385 |
|
| 2018 |
Wilkes JG, O'Leary BR, Du J, Klinger AR, Sibenaller ZA, Doskey CM, Gibson-Corley KN, Alexander MS, Tsai S, Buettner GR, Cullen JJ. Pharmacologic ascorbate (P-AscH-) suppresses hypoxia-inducible Factor-1α (HIF-1α) in pancreatic adenocarcinoma. Clinical & Experimental Metastasis. PMID 29396728 DOI: 10.1007/S10585-018-9876-Z |
0.309 |
|
| 2018 |
Heer CD, Davis AB, Riffe DB, Wagner BA, Falls KC, Allen BG, Buettner GR, Beardsley RA, Riley DP, Spitz DR. Superoxide Dismutase Mimetic GC4419 Enhances the Oxidation of Pharmacological Ascorbate and Its Anticancer Effects in an H₂O₂-Dependent Manner. Antioxidants (Basel, Switzerland). 7. PMID 29351198 DOI: 10.3390/Antiox7010018 |
0.408 |
|
| 2018 |
Stolwijk J, Wagner B, McCormick M, Zakharia Y, Spitz D, Buettner G. Optimization of selenium in cell culture media to maximize selenoenzyme activity Free Radical Biology and Medicine. 128: S121. DOI: 10.1016/J.Freeradbiomed.2018.10.298 |
0.335 |
|
| 2018 |
Wagner B, Buranasudja V, Du J, Cullen J, Buettner G. Pharmacologic ascorbate induces DNA damage, alters the bioenergetic profile, but does not influence cellular respiration or glycolysis in human pancreatic cancer cells Free Radical Biology and Medicine. 128: S95. DOI: 10.1016/J.Freeradbiomed.2018.10.225 |
0.754 |
|
| 2018 |
Gibson A, O'Leary B, Alexander M, Du J, Wagner B, Goswami P, Buettner G, Cullen J. Pharmacological ascorbate enhances expression of dual oxidase which mediates sustained toxicity via alterations in cellular metabolism Free Radical Biology and Medicine. 128: S71. DOI: 10.1016/J.Freeradbiomed.2018.10.152 |
0.374 |
|
| 2017 |
Schoenfeld JD, Sibenaller ZA, Mapuskar KA, Bradley MD, Wagner BA, Buettner GR, Monga V, Milhem M, Spitz DR, Allen BG. Redox active metals and H2O2 mediate the increased efficacy of pharmacological ascorbate in combination with gemcitabine or radiation in pre-clinical sarcoma models. Redox Biology. 14: 417-422. PMID 29069637 DOI: 10.1016/J.Redox.2017.09.012 |
0.364 |
|
| 2017 |
Brandt KE, Falls KC, Schoenfeld JD, Rodman SN, Gu Z, Zhan F, Cullen JJ, Wagner BA, Buettner GR, Allen BG, Berg DJ, Spitz DR, Fath MA. Augmentation of intracellular iron using iron sucrose enhances the toxicity of pharmacological ascorbate in colon cancer cells. Redox Biology. 14: 82-87. PMID 28886484 DOI: 10.1016/J.Redox.2017.08.017 |
0.346 |
|
| 2017 |
Schoenfeld JD, Sibenaller ZA, Mapuskar KA, Wagner BA, Cramer-Morales KL, Furqan M, Sandhu S, Carlisle TL, Smith MC, Abu Hejleh T, Berg DJ, Zhang J, Keech J, Parekh KR, Bhatia S, ... ... Buettner GR, et al. O2(⋅-) and H2O2-Mediated Disruption of Fe Metabolism Causes the Differential Susceptibility of NSCLC and GBM Cancer Cells to Pharmacological Ascorbate. Cancer Cell. 32: 268. PMID 28810149 DOI: 10.1016/J.Ccell.2017.07.008 |
0.321 |
|
| 2017 |
Schoenfeld JD, Sibenaller ZA, Mapuskar KA, Wagner BA, Cramer-Morales KL, Furqan M, Sandhu S, Carlisle TL, Smith MC, Abu Hejleh T, Berg DJ, Zhang J, Keech J, Parekh KR, Bhatia S, ... ... Buettner GR, et al. O2(⋅-) and H2O2-Mediated Disruption of Fe Metabolism Causes the Differential Susceptibility of NSCLC and GBM Cancer Cells to Pharmacological Ascorbate. Cancer Cell. PMID 28366679 DOI: 10.1016/J.Ccell.2017.02.018 |
0.395 |
|
| 2017 |
Erudaitius D, Huang A, Kazmi S, Buettner GR, Rodgers VG. Peroxiporin Expression Is an Important Factor for Cancer Cell Susceptibility to Therapeutic H2O2: Implications for Pharmacological Ascorbate Therapy. Plos One. 12: e0170442. PMID 28107421 DOI: 10.1371/Journal.Pone.0170442 |
0.376 |
|
| 2017 |
Wagner BA, Buranasudja V, Buettner GR. Quantitative Differences in Physical Size, H 2 O 2 -Removal, and Cellular Bioenergetics in the Human Pancreatic Cancer Cell Lines MIA PaCa-2 and Panc-1: Impact on Susceptibilities to Ascorbate/H 2 O 2 Free Radical Biology and Medicine. 112: 178. DOI: 10.1016/J.Freeradbiomed.2017.10.279 |
0.396 |
|
| 2017 |
Buranasudja V, Doskey CM, Wagner BA, Du J, Gordon DJ, Koppenhafer S, Cullen JJ, Buettner GR. DNA Damage and Energy Crisis are Central in the Mechanism for the Cytotoxicity of Pharmacological Ascorbate in Cancer Treatment Free Radical Biology and Medicine. 112: 162. DOI: 10.1016/J.Freeradbiomed.2017.10.249 |
0.744 |
|
| 2017 |
Buettner GR, Buranasudja V, Doskey CM, Wagner BA. Estimating and Partitioning the Flux of ATP in Cells in Culture using mol cell -1 s -1 and the Stoichiometries of Metabolism Free Radical Biology and Medicine. 112: 161. DOI: 10.1016/J.Freeradbiomed.2017.10.248 |
0.752 |
|
| 2017 |
Heer CD, Davis AB, Riffe DB, Wagner BA, Falls KC, Buettner GR, Beardsley RA, Riley DP, Allen BG, Spitz DR. Penta-azamacrocyclic SOD Mimetics Enhance Pharmacological Ascorbate Oxidation and Anticancer effects in an H 2 O 2 -dependent Manner Free Radical Biology and Medicine. 112: 90-91. DOI: 10.1016/J.Freeradbiomed.2017.10.132 |
0.381 |
|
| 2016 |
Doskey CM, Buranasudja V, Wagner BA, Wilkes JG, Du J, Cullen JJ, Buettner GR. Tumor cells have decreased ability to metabolize H2O2: Implications for pharmacological ascorbate in cancer therapy. Redox Biology. 10: 274-284. PMID 27833040 DOI: 10.1016/J.Redox.2016.10.010 |
0.759 |
|
| 2016 |
Allen BG, Schoenfeld JD, Sibenaller ZA, Mapuskar KA, Furqan M, Abu Hejleh T, Wagner B, Cullen JJ, Buettner GR, Buatti J, Spitz D. Pharmacological Ascorbate Enhances the Response of Non-Small Cell Lung Cancer (NSCLC) to Radiation and Chemotherapy Via Disruptions of Redox Active Iron Leading to Increased H2O2. International Journal of Radiation Oncology, Biology, Physics. 96: S239. PMID 27675877 DOI: 10.1016/J.Ijrobp.2016.06.594 |
0.314 |
|
| 2016 |
Anderson DG, Florang VR, Schamp JH, Buettner GR, Doorn JA. Antioxidant-Mediated Modulation of Protein Reactivity for 3,4 Dihydroxyphenylacetaldehyde, a Toxic Dopamine Metabolite. Chemical Research in Toxicology. PMID 27268734 DOI: 10.1021/Acs.Chemrestox.5B00528 |
0.364 |
|
| 2016 |
Witmer JR, Wetherell BJ, Wagner BA, Du J, Cullen JJ, Buettner GR. Direct spectrophotometric measurement of supra-physiological levels of ascorbate in plasma. Redox Biology. 8: 298-304. PMID 26928133 DOI: 10.1016/J.Redox.2016.02.004 |
0.762 |
|
| 2016 |
Xiao W, Sarsour EH, Wagner BA, Doskey CM, Buettner GR, Domann FE, Goswami PC. Succinate dehydrogenase activity regulates PCB3-quinone-induced metabolic oxidative stress and toxicity in HaCaT human keratinocytes. Archives of Toxicology. 90: 319-32. PMID 25417049 DOI: 10.1007/S00204-014-1407-3 |
0.364 |
|
| 2016 |
Buettner GR, Doskey CM, Buranasudja V, Wagner BA. Leveraging Data from Bioenergetic Experiments to Determine the Absolute Flux of ATP in Cells from Respiration and Glycolysis Free Radical Biology and Medicine. 100: S182. DOI: 10.1016/J.Freeradbiomed.2016.10.478 |
0.743 |
|
| 2016 |
Du J, Doskey CM, Wilkes JG, Buettner GR, Cullen JJ. Catalase as a Potential Biomarker of Pharmacological Ascorbate Cancer Therapy Free Radical Biology and Medicine. 100: S121. DOI: 10.1016/J.Freeradbiomed.2016.10.312 |
0.366 |
|
| 2016 |
Klinger AR, Kalen AL, Son J, Sarsour EH, Du J, Wagner BA, Buettner GR, Goswami PC, Cullen JJ. Dual Oxidase 1 Promotes Crosstalk between Extracellular H2O2 and Mitochondrial Respiration During Pharmacological Ascorbate Induced Toxicity of Pancreatic Cancer Cells Free Radical Biology and Medicine. 100: S42. DOI: 10.1016/J.Freeradbiomed.2016.10.108 |
0.385 |
|
| 2016 |
Wagner BA, Buettner GR. Quantitative Changes in Dihydroethidium (DHE) Oxidation Products from Isolated Mitochondria While Respiring on Select Substrates and the Effects Mitochondrial Inhibitors Commonly Used in Bioenergetic Profiling Free Radical Biology and Medicine. 100: S31. DOI: 10.1016/J.Freeradbiomed.2016.10.079 |
0.322 |
|
| 2015 |
Rabovsky AB, Buettner GR, Fink B. In vivo imaging of free radicals produced by multivitamin-mineral supplements. Bmc Nutrition. 1. PMID 26705481 DOI: 10.1186/S40795-015-0025-7 |
0.328 |
|
| 2015 |
Wangpradit O, Rahaman A, Mariappan SV, Buettner GR, Robertson LW, Luthe G. Breaking the dogma: PCB-derived semiquinone free radicals do not form covalent adducts with DNA, GSH, and amino acids. Environmental Science and Pollution Research International. PMID 26396011 DOI: 10.1007/S11356-015-5007-4 |
0.326 |
|
| 2015 |
Doskey CM, van 't Erve TJ, Wagner BA, Buettner GR. Moles of a Substance per Cell Is a Highly Informative Dosing Metric in Cell Culture. Plos One. 10: e0132572. PMID 26172833 DOI: 10.1371/Journal.Pone.0132572 |
0.749 |
|
| 2015 |
Du J, Cieslak JA, Welsh JL, Sibenaller ZA, Allen BG, Wagner BA, Kalen AL, Doskey CM, Strother RK, Button AM, Mott SL, Smith B, Tsai S, Mezhir J, Goswami PC, ... ... Buettner GR, et al. Pharmacological Ascorbate Radiosensitizes Pancreatic Cancer. Cancer Research. PMID 26081808 DOI: 10.1158/0008-5472.Can-14-1707 |
0.399 |
|
| 2015 |
Du J, Wagner BA, Buettner GR, Cullen JJ. Role of labile iron in the toxicity of pharmacological ascorbate. Free Radical Biology & Medicine. 84: 289-95. PMID 25857216 DOI: 10.1016/J.Freeradbiomed.2015.03.033 |
0.365 |
|
| 2015 |
Cieslak JA, Strother RK, Rawal M, Du J, Doskey CM, Schroeder SR, Button A, Wagner BA, Buettner GR, Cullen JJ. Manganoporphyrins and ascorbate enhance gemcitabine cytotoxicity in pancreatic cancer. Free Radical Biology & Medicine. 83: 227-37. PMID 25725418 DOI: 10.1016/J.Freeradbiomed.2015.02.018 |
0.719 |
|
| 2015 |
Van 't Erve TJ, Wagner BA, Martin SM, Knudson CM, Blendowski R, Keaton M, Holt T, Hess JR, Buettner GR, Ryckman KK, Darbro BW, Murray JC, Raife TJ. The heritability of hemolysis in stored human red blood cells. Transfusion. 55: 1178-85. PMID 25644965 DOI: 10.1111/Trf.12992 |
0.75 |
|
| 2015 |
O'Leary BR, Fath MA, Bellizzi AM, Hrabe JE, Button AM, Allen BG, Case AJ, Altekruse S, Wagner BA, Buettner GR, Lynch CF, Hernandez BY, Cozen W, Beardsley RA, Keene J, et al. Loss of SOD3 (EcSOD) Expression Promotes an Aggressive Phenotype in Human Pancreatic Ductal Adenocarcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 1741-51. PMID 25634994 DOI: 10.1158/1078-0432.Ccr-14-1959 |
0.347 |
|
| 2015 |
Buettner GR. Moving free radical and redox biology ahead in the next decade(s). Free Radical Biology & Medicine. 78: 236-8. PMID 25450329 DOI: 10.1016/J.Freeradbiomed.2014.10.578 |
0.379 |
|
| 2015 |
Doskey CM, Wagner BA, Buranasudja V, Du J, Cullen J, Buettner GR. Differences in the Capacities of Tumor and Normal Cells to Remove Extracellular Hydrogen Peroxide: Exploring the Mechanism of Pharmacological Ascorbate in Cancer Therapy Free Radical Biology and Medicine. 87: S65. DOI: 10.1016/J.Freeradbiomed.2015.10.169 |
0.745 |
|
| 2014 |
Eckers JC, Kalen AL, Sarsour EH, Tompkins VS, Janz S, Son JM, Doskey CM, Buettner GR, Goswami PC. Forkhead box M1 regulates quiescence-associated radioresistance of human head and neck squamous carcinoma cells. Radiation Research. 182: 420-9. PMID 25229973 DOI: 10.1667/Rr13726.1 |
0.344 |
|
| 2014 |
Ozden O, Park SH, Wagner BA, Yong Song H, Zhu Y, Vassilopoulos A, Jung B, Buettner GR, Gius D. SIRT3 deacetylates and increases pyruvate dehydrogenase activity in cancer cells. Free Radical Biology & Medicine. 76: 163-72. PMID 25152236 DOI: 10.1016/J.Freeradbiomed.2014.08.001 |
0.336 |
|
| 2014 |
van 't Erve TJ, Doskey CM, Wagner BA, Hess JR, Darbro BW, Ryckman KK, Murray JC, Raife TJ, Buettner GR. Heritability of glutathione and related metabolites in stored red blood cells. Free Radical Biology & Medicine. 76: 107-13. PMID 25108189 DOI: 10.1016/J.Freeradbiomed.2014.07.040 |
0.757 |
|
| 2014 |
van 't Erve TJ, Wagner BA, Martin SM, Knudson CM, Blendowski R, Keaton M, Holt T, Hess JR, Buettner GR, Ryckman KK, Darbro BW, Murray JC, Raife TJ. The heritability of metabolite concentrations in stored human red blood cells. Transfusion. 54: 2055-63. PMID 24601981 DOI: 10.1111/Trf.12605 |
0.748 |
|
| 2014 |
Sibenaller ZA, Welsh JL, Du C, Witmer JR, Schrock HE, Du J, Buettner GR, Goswami PC, Cieslak JA, Cullen JJ. Extracellular superoxide dismutase suppresses hypoxia-inducible factor-1α in pancreatic cancer. Free Radical Biology & Medicine. 69: 357-66. PMID 24509158 DOI: 10.1016/J.Freeradbiomed.2014.02.002 |
0.777 |
|
| 2014 |
Cieslak JA, Strother R, Du J, Rawal M, Doskey CM, Schroeder SR, Wagner BA, Buettner GR, Cullen JJ. The Addition of Manganoporphyrins and Ascorbate to Standard of Care Chemotherapy Enhances Tumor-Specific Cytotoxicity in Pancreatic Cancer Free Radical Biology and Medicine. 76: S122-S123. DOI: 10.1016/J.Freeradbiomed.2014.10.184 |
0.651 |
|
| 2013 |
Moser JC, Rawal M, Wagner BA, Du J, Cullen JJ, Buettner GR. Pharmacological ascorbate and ionizing radiation (IR) increase labile iron in pancreatic cancer. Redox Biology. 2: 22-7. PMID 24396727 DOI: 10.1016/J.Redox.2013.11.005 |
0.668 |
|
| 2013 |
van 't Erve TJ, Wagner BA, Ryckman KK, Raife TJ, Buettner GR. The concentration of glutathione in human erythrocytes is a heritable trait. Free Radical Biology & Medicine. 65: 742-9. PMID 23938402 DOI: 10.1016/J.Freeradbiomed.2013.08.002 |
0.762 |
|
| 2013 |
Wagner BA, Witmer JR, van 't Erve TJ, Buettner GR. An Assay for the Rate of Removal of Extracellular Hydrogen Peroxide by Cells. Redox Biology. 1: 210-217. PMID 23936757 DOI: 10.1016/J.Redox.2013.01.011 |
0.775 |
|
| 2013 |
Rawal M, Schroeder SR, Wagner BA, Cushing CM, Welsh JL, Button AM, Du J, Sibenaller ZA, Buettner GR, Cullen JJ. Manganoporphyrins increase ascorbate-induced cytotoxicity by enhancing H2O2 generation. Cancer Research. 73: 5232-41. PMID 23764544 DOI: 10.1158/0008-5472.Can-13-0470 |
0.72 |
|
| 2013 |
Olney KE, Du J, van 't Erve TJ, Witmer JR, Sibenaller ZA, Wagner BA, Buettner GR, Cullen JJ. Inhibitors of hydroperoxide metabolism enhance ascorbate-induced cytotoxicity. Free Radical Research. 47: 154-63. PMID 23205739 DOI: 10.1016/J.Freeradbiomed.2010.10.132 |
0.772 |
|
| 2013 |
Du J, Nelson ES, Simons AL, Olney KE, Moser JC, Schrock HE, Wagner BA, Buettner GR, Smith BJ, Teoh ML, Tsao MS, Cullen JJ. Regulation of pancreatic cancer growth by superoxide. Molecular Carcinogenesis. 52: 555-67. PMID 22392697 DOI: 10.1002/Mc.21891 |
0.325 |
|
| 2013 |
Buettner GR, Wagner BA, Rodgers VG. Quantitative redox biology: an approach to understand the role of reactive species in defining the cellular redox environment. Cell Biochemistry and Biophysics. 67: 477-83. PMID 22161621 DOI: 10.1007/S12013-011-9320-3 |
0.333 |
|
| 2013 |
van't Erve TJ, Wagner B, Ryckman K, Raife T, Buettner G. The Concentration of Glutathione in Red Blood Cells is a Heritable Trait Free Radical Biology and Medicine. 65: S148. DOI: 10.1016/J.Freeradbiomed.2013.10.771 |
0.317 |
|
| 2013 |
Schroeder SR, Wagner BA, Rawal M, Doskey CM, Cullen JJ, Buettner GR. Quantitating Weak EPR Spectra of Free Radicals in Biological Samples Free Radical Biology and Medicine. 65: S93. DOI: 10.1016/J.Freeradbiomed.2013.10.622 |
0.652 |
|
| 2013 |
Wagner Ba, Welsh JL, Van't Erve TJ, Schroeder SR, Sibenaller Za, Doskey CM, Du J, Cullen JJ, Buettner GR. Maintenance of Cancer Cell Bioenergetics during Cell Death Processes Following Ionizing Radiation Free Radical Biology and Medicine. 65: S25-S26. DOI: 10.1016/J.Freeradbiomed.2013.10.445 |
0.323 |
|
| 2013 |
Rawal M, Schroeder SR, Du J, Welsh JL, Sibenaller ZA, Wagner BA, Buettner GR, Cullen JJ. Manganoporphyrins Enhance Ascorbate-Induced Cytotoxicity Selectively in Pancreatic Cancer Free Radical Biology and Medicine. 65: S24. DOI: 10.1016/J.Freeradbiomed.2013.10.441 |
0.66 |
|
| 2012 |
Du J, Cullen JJ, Buettner GR. Ascorbic acid: chemistry, biology and the treatment of cancer. Biochimica Et Biophysica Acta. 1826: 443-57. PMID 22728050 DOI: 10.1016/J.Bbcan.2012.06.003 |
0.358 |
|
| 2012 |
Sarsour EH, Kalen AL, Xiao Z, Veenstra TD, Chaudhuri L, Venkataraman S, Reigan P, Buettner GR, Goswami PC. Manganese superoxide dismutase regulates a metabolic switch during the mammalian cell cycle. Cancer Research. 72: 3807-16. PMID 22710435 DOI: 10.1158/0008-5472.Can-11-1063 |
0.342 |
|
| 2012 |
Brown CO, Salem K, Wagner BA, Bera S, Singh N, Tiwari A, Choudhury A, Buettner GR, Goel A. Interleukin-6 counteracts therapy-induced cellular oxidative stress in multiple myeloma by up-regulating manganese superoxide dismutase. The Biochemical Journal. 444: 515-27. PMID 22471522 DOI: 10.1042/Bj20112019 |
0.317 |
|
| 2012 |
Sarsour EH, Kumar MG, Kalen AL, Goswami M, Buettner GR, Goswami PC. MnSOD activity regulates hydroxytyrosol-induced extension of chronological lifespan. Age (Dordrecht, Netherlands). 34: 95-109. PMID 21384152 DOI: 10.1007/S11357-011-9223-7 |
0.303 |
|
| 2012 |
Rawal M, Schroeder SR, Wagner BA, Du J, Buettner GR, Cullen JJ. Potential of Manganoporphyrins to Enhance the Efficacy of Pharmacological Ascorbate in the Treatment of Pancreatic Cancer Free Radical Biology and Medicine. 53: S115. DOI: 10.1016/J.Freeradbiomed.2012.10.283 |
0.651 |
|
| 2012 |
Du J, Rawal M, Moser JC, Olney KE, Buettner GR, Cullen JJ. The Role of Redox Active Transition Metals in Ascorbate-Induced Cytotoxicity in Pancreatic Cancer Free Radical Biology and Medicine. 53: S42. DOI: 10.1016/J.Freeradbiomed.2012.10.107 |
0.658 |
|
| 2011 |
Wagner BA, Venkataraman S, Buettner GR. The rate of oxygen utilization by cells. Free Radical Biology & Medicine. 51: 700-12. PMID 21664270 DOI: 10.1016/J.Freeradbiomed.2011.05.024 |
0.353 |
|
| 2011 |
Anderson DG, Mariappan SV, Buettner GR, Doorn JA. Oxidation of 3,4-dihydroxyphenylacetaldehyde, a toxic dopaminergic metabolite, to a semiquinone radical and an ortho-quinone. The Journal of Biological Chemistry. 286: 26978-86. PMID 21642436 DOI: 10.1074/Jbc.M111.249532 |
0.364 |
|
| 2011 |
Buettner GR. Superoxide dismutase in redox biology: the roles of superoxide and hydrogen peroxide. Anti-Cancer Agents in Medicinal Chemistry. 11: 341-6. PMID 21453242 DOI: 10.2174/187152011795677544 |
0.411 |
|
| 2011 |
Rawal M, Schroeder SR, Du J, Wagner B, Buettner GR, Cullen JJ. Manganoporphyrin MnTMPyP Enhances Ascorbate-Induced Cytotoxicity in Pancreatic Cancer Cells Via Generation of H2O2 Free Radical Biology and Medicine. 51: S128. DOI: 10.1016/J.Freeradbiomed.2011.10.336 |
0.695 |
|
| 2011 |
Wagner Ba, van 't Erve TJ, Witmer JR, Buettner GR. Dissecting Superoxide Production by HL-60 Cells Using DHE and Spin Trapping Free Radical Biology and Medicine. 51: S141. DOI: 10.1016/J.Freeradbiomed.2011.10.303 |
0.773 |
|
| 2011 |
van 't Erve TJ, Wagner B, Buettner G. Quinone Containing Xenobiotics Oxidize the Intracellular Redox Buffer Depending On Their Structure: the Chemistry and Biology of a Redox Poison Free Radical Biology and Medicine. 51: S151. DOI: 10.1016/J.Freeradbiomed.2011.10.263 |
0.326 |
|
| 2011 |
Witmer JR, Wagner BA, Buettner GR. Absolute Quantitation of Active and Total Catalase Free Radical Biology and Medicine. 51: S24. DOI: 10.1016/J.Freeradbiomed.2011.10.057 |
0.761 |
|
| 2010 |
Rabovsky AB, Komarov AM, Ivie JS, Buettner GR. Minimization of free radical damage by metal catalysis of multivitamin/multimineral supplements. Nutrition Journal. 9: 61. PMID 21092298 DOI: 10.1186/1475-2891-9-61 |
0.342 |
|
| 2010 |
Wangpradit O, Moman E, Nolan KB, Buettner GR, Robertson LW, Luthe G. Observation of an unusual electronically distorted semiquinone radical of PCB metabolites in the active site of prostaglandin H synthase-2. Chemosphere. 81: 1501-8. PMID 20843536 DOI: 10.1016/J.Chemosphere.2010.08.041 |
0.308 |
|
| 2010 |
Song Y, Buettner GR. Thermodynamic and kinetic considerations for the reaction of semiquinone radicals to form superoxide and hydrogen peroxide. Free Radical Biology & Medicine. 49: 919-62. PMID 20493944 DOI: 10.1016/J.Freeradbiomed.2010.05.009 |
0.317 |
|
| 2010 |
Du J, Martin SM, Levine M, Wagner BA, Buettner GR, Wang SH, Taghiyev AF, Du C, Knudson CM, Cullen JJ. Mechanisms of ascorbate-induced cytotoxicity in pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 509-20. PMID 20068072 DOI: 10.1158/1078-0432.Ccr-09-1713 |
0.31 |
|
| 2010 |
Pasanphan W, Buettner GR, Chirachanchai S. Chitosan gallate as a novel potential polysaccharide antioxidant: an EPR study. Carbohydrate Research. 345: 132-40. PMID 19889400 DOI: 10.1016/J.Carres.2009.09.038 |
0.31 |
|
| 2010 |
Bian W, Van ’t Erve TJ, Wagner B, Witmer J, Buettner G. Oxidation of Glutathione by Sodium Selenite and SelenoLMethionine Free Radical Biology and Medicine. 49: S208. DOI: 10.1016/J.Freeradbiomed.2010.10.602 |
0.778 |
|
| 2010 |
Wagner BA, van 't Erve TJ, Witmer JR, Bian W, Buettner GR. Quantitative Redox Biological Modeling and the Maintenance of Redox Status and Cell Signaling Fidelity Free Radical Biology and Medicine. 49: S104. DOI: 10.1016/J.Freeradbiomed.2010.10.275 |
0.774 |
|
| 2010 |
Witmer JR, Wagner BA, Buettner GR. Absolute Quantitation of SOD Activity Free Radical Biology and Medicine. 49: S89. DOI: 10.1016/J.Freeradbiomed.2010.10.228 |
0.763 |
|
| 2010 |
van 't Erve TJ, Wagner B, Witmer J, Bian W, Buettner G. Predicting Cell Vulnerability to Hydrogen Peroxide Generating Compounds: Possible Use in AntiCancer Therapies Free Radical Biology and Medicine. 49: S72-S73. DOI: 10.1016/J.Freeradbiomed.2010.10.181 |
0.768 |
|
| 2010 |
Du J, Olney K, Schrock H, Moser J, Wagner B, Sibenaller Z, Buettner G, Cullen J. Tempol Inhibits Pancreatic Cancer Cell Growth Free Radical Biology and Medicine. 49: S58. DOI: 10.1016/J.Freeradbiomed.2010.10.133 |
0.307 |
|
| 2009 |
Song Y, Wagner BA, Witmer JR, Lehmler HJ, Buettner GR. Nonenzymatic displacement of chlorine and formation of free radicals upon the reaction of glutathione with PCB quinones. Proceedings of the National Academy of Sciences of the United States of America. 106: 9725-30. PMID 19497881 DOI: 10.1073/Pnas.0810352106 |
0.776 |
|
| 2009 |
Suh YW, Buettner GR, Venkataraman S, Treimer SE, Robertson LW, Ludewig G. UVA/B-induced formation of free radicals from decabromodiphenyl ether. Environmental Science & Technology. 43: 2581-8. PMID 19452920 DOI: 10.1021/Es8022978 |
0.331 |
|
| 2009 |
Case AJ, Wagner BA, Buettner GR, Domann FE. Deficiency of MnSOD in Hematopoietic Stem Cells Causes a Sideroblastic Anemia-Like Phenotype. Blood. 114: 1991-1991. DOI: 10.1182/Blood.V114.22.1991.1991 |
0.338 |
|
| 2008 |
Song Y, Buettner GR, Parkin S, Wagner BA, Robertson LW, Lehmler HJ. Chlorination increases the persistence of semiquinone free radicals derived from polychlorinated biphenyl hydroquinones and quinones. The Journal of Organic Chemistry. 73: 8296-304. PMID 18839991 DOI: 10.1021/Jo801397G |
0.334 |
|
| 2008 |
Venkatesha VA, Venkataraman S, Sarsour EH, Kalen AL, Buettner GR, Robertson LW, Lehmler HJ, Goswami PC. Catalase ameliorates polychlorinated biphenyl-induced cytotoxicity in nonmalignant human breast epithelial cells. Free Radical Biology & Medicine. 45: 1094-102. PMID 18691649 DOI: 10.1016/J.Freeradbiomed.2008.07.007 |
0.375 |
|
| 2008 |
Song Y, Wagner BA, Lehmler HJ, Buettner GR. Semiquinone radicals from oxygenated polychlorinated biphenyls: electron paramagnetic resonance studies. Chemical Research in Toxicology. 21: 1359-67. PMID 18549251 DOI: 10.1021/Tx8000175 |
0.357 |
|
| 2008 |
Cullen J, Buettner GR, Du J, Levine M. W1392 Ascorbate-Induced Cytotoxicity in Pancreatic Cancer Gastroenterology. 134: A-694-A-695. DOI: 10.1016/S0016-5085(08)63242-4 |
0.301 |
|
| 2007 |
Ng CF, Schafer FQ, Buettner GR, Rodgers VG. The rate of cellular hydrogen peroxide removal shows dependency on GSH: mathematical insight into in vivo H2O2 and GPx concentrations. Free Radical Research. 41: 1201-11. PMID 17886026 DOI: 10.1080/10715760701625075 |
0.336 |
|
| 2007 |
Chen Q, Espey MG, Sun AY, Lee JH, Krishna MC, Shacter E, Choyke PL, Pooput C, Kirk KL, Buettner GR, Levine M. Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo. Proceedings of the National Academy of Sciences of the United States of America. 104: 8749-54. PMID 17502596 DOI: 10.1073/Pnas.0702854104 |
0.32 |
|
| 2007 |
Wagner BA, Teesch LM, Buettner GR, Britigan BE, Burns CP, Reszka KJ. Inactivation of anthracyclines by serum heme proteins. Chemical Research in Toxicology. 20: 920-6. PMID 17497896 DOI: 10.1021/Tx700002F |
0.378 |
|
| 2007 |
Vislisel JM, Schafer FQ, Buettner GR. A simple and sensitive assay for ascorbate using a plate reader. Analytical Biochemistry. 365: 31-9. PMID 17433246 DOI: 10.1016/J.Ab.2007.03.002 |
0.33 |
|
| 2007 |
Uc A, Reszka KJ, Buettner GR, Stokes JB. Tin protoporphyrin induces intestinal chloride secretion by inducing light oxidation processes. American Journal of Physiology. Cell Physiology. 292: C1906-14. PMID 17215323 DOI: 10.1152/Ajpcell.00550.2006 |
0.376 |
|
| 2006 |
Buettner GR, Ng CF, Wang M, Rodgers VG, Schafer FQ. A new paradigm: manganese superoxide dismutase influences the production of H2O2 in cells and thereby their biological state. Free Radical Biology & Medicine. 41: 1338-50. PMID 17015180 DOI: 10.1016/J.Freeradbiomed.2006.07.015 |
0.364 |
|
| 2006 |
Luo J, Li L, Zhang Y, Spitz DR, Buettner GR, Oberley LW, Domann FE. Inactivation of primary antioxidant enzymes in mouse keratinocytes by photodynamically generated singlet oxygen. Antioxidants & Redox Signaling. 8: 1307-14. PMID 16910778 DOI: 10.1089/Ars.2006.8.1307 |
0.349 |
|
| 2006 |
Kramarenko GG, Hummel SG, Martin SM, Buettner GR. Ascorbate reacts with singlet oxygen to produce hydrogen peroxide. Photochemistry and Photobiology. 82: 1634-7. PMID 16898858 DOI: 10.1562/2006-01-12-Rn-774 |
0.331 |
|
| 2006 |
Reszka KJ, McCormick ML, Buettner GR, Hart CM, Britigan BE. Nitric oxide decreases the stability of DMPO spin adducts. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 15: 133-41. PMID 16647868 DOI: 10.1016/J.Niox.2006.03.004 |
0.363 |
|
| 2006 |
Kramarenko GG, Wilke WW, Dayal D, Buettner GR, Schafer FQ. Ascorbate enhances the toxicity of the photodynamic action of Verteporfin in HL-60 cells. Free Radical Biology & Medicine. 40: 1615-27. PMID 16632121 DOI: 10.1016/J.Freeradbiomed.2005.12.027 |
0.427 |
|
| 2006 |
Hummel SG, Fischer AJ, Martin SM, Schafer FQ, Buettner GR. Nitric oxide as a cellular antioxidant: a little goes a long way. Free Radical Biology & Medicine. 40: 501-6. PMID 16443165 DOI: 10.1016/J.Freeradbiomed.2005.08.047 |
0.37 |
|
| 2005 |
Wang M, Kirk JS, Venkataraman S, Domann FE, Zhang HJ, Schafer FQ, Flanagan SW, Weydert CJ, Spitz DR, Buettner GR, Oberley LW. Manganese superoxide dismutase suppresses hypoxic induction of hypoxia-inducible factor-1alpha and vascular endothelial growth factor. Oncogene. 24: 8154-66. PMID 16170370 DOI: 10.1038/Sj.Onc.1208986 |
0.339 |
|
| 2005 |
Chen Q, Espey MG, Krishna MC, Mitchell JB, Corpe CP, Buettner GR, Shacter E, Levine M. Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues. Proceedings of the National Academy of Sciences of the United States of America. 102: 13604-9. PMID 16157892 DOI: 10.1073/Pnas.0506390102 |
0.361 |
|
| 2005 |
Wagner BA, Evig CB, Reszka KJ, Buettner GR, Burns CP. Doxorubicin increases intracellular hydrogen peroxide in PC3 prostate cancer cells. Archives of Biochemistry and Biophysics. 440: 181-90. PMID 16054588 DOI: 10.1016/J.Abb.2005.06.015 |
0.364 |
|
| 2005 |
Ahmad IM, Aykin-Burns N, Sim JE, Walsh SA, Higashikubo R, Buettner GR, Venkataraman S, Mackey MA, Flanagan SW, Oberley LW, Spitz DR. Mitochondrial O2*- and H2O2 mediate glucose deprivation-induced stress in human cancer cells. The Journal of Biological Chemistry. 280: 4254-63. PMID 15561720 DOI: 10.1074/Jbc.M411662200 |
0.358 |
|
| 2005 |
Venkataraman S, Jiang X, Weydert C, Zhang Y, Zhang HJ, Goswami PC, Ritchie JM, Oberley LW, Buettner GR. Manganese superoxide dismutase overexpression inhibits the growth of androgen-independent prostate cancer cells. Oncogene. 24: 77-89. PMID 15543233 DOI: 10.1038/Sj.Onc.1208145 |
0.355 |
|
| 2004 |
Venkataraman S, Wagner BA, Jiang X, Wang HP, Schafer FQ, Ritchie JM, Patrick BC, Oberley LW, Buettner GR. Overexpression of manganese superoxide dismutase promotes the survival of prostate cancer cells exposed to hyperthermia. Free Radical Research. 38: 1119-32. PMID 15512801 DOI: 10.1080/10715760400010470 |
0.414 |
|
| 2004 |
Evig CB, Kelley EE, Weydert CJ, Chu Y, Buettner GR, Burns CP. Endogenous production and exogenous exposure to nitric oxide augment doxorubicin cytotoxicity for breast cancer cells but not cardiac myoblasts. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 10: 119-29. PMID 15158691 DOI: 10.1016/J.Niox.2004.03.006 |
0.657 |
|
| 2004 |
Venkataraman S, Schafer FQ, Buettner GR. Detection of lipid radicals using EPR. Antioxidants & Redox Signaling. 6: 631-8. PMID 15130290 DOI: 10.1089/152308604773934396 |
0.367 |
|
| 2004 |
Carter AB, Tephly LA, Venkataraman S, Oberley LW, Zhang Y, Buettner GR, Spitz DR, Hunninghake GW. High levels of catalase and glutathione peroxidase activity dampen H2O2 signaling in human alveolar macrophages. American Journal of Respiratory Cell and Molecular Biology. 31: 43-53. PMID 14962975 DOI: 10.1165/Rcmb.2003-0377Oc |
0.312 |
|
| 2003 |
Lam E, Kelley E, Martin S, Buettner G. Tobacco xenobiotics release nitric oxide. Tobacco Induced Diseases. 1: 207-211. PMID 19570261 DOI: 10.1186/1617-9625-1-3-207 |
0.6 |
|
| 2003 |
Zhang Y, Davies LR, Martin SM, Coddington WJ, Miller FJ, Buettner GR, Kerber RE. The nitric oxide donor S-nitroso-N-acetylpenicillamine (SNAP) increases free radical generation and degrades left ventricular function after myocardial ischemia-reperfusion. Resuscitation. 59: 345-52. PMID 14659604 DOI: 10.1016/S0300-9572(03)00240-5 |
0.336 |
|
| 2003 |
Zhao L, Wang HP, Zhang HJ, Weydert CJ, Domann FE, Oberley LW, Buettner GR. L-PhGPx expression can be suppressed by antisense oligodeoxynucleotides. Archives of Biochemistry and Biophysics. 417: 212-8. PMID 12941303 DOI: 10.1016/S0003-9861(03)00342-4 |
0.34 |
|
| 2003 |
Wang HP, Schafer FQ, Goswami PC, Oberley LW, Buettner GR. Phospholipid hydroperoxide glutathione peroxidase induces a delay in G1 of the cell cycle. Free Radical Research. 37: 621-30. PMID 12868489 DOI: 10.1080/1071576031000088283 |
0.371 |
|
| 2003 |
Clark CB, Zhang Y, Martin SM, Ray Davies L, Xu L, Kregel KC, Miller FJ, Buettner GR, Kerber RE. The nitric oxide synthase inhibitor N(G)-nitro-L-arginine decreases defibrillation-induced free radical generation. Resuscitation. 57: 101-8. PMID 12668306 DOI: 10.1016/S0300-9572(02)00413-6 |
0.322 |
|
| 2003 |
Baker MT, Gregerson MS, Martin SM, Buettner GR. Free radical and drug oxidation products in an intensive care unit sedative: propofol with sulfite. Critical Care Medicine. 31: 787-92. PMID 12626985 DOI: 10.1097/01.Ccm.0000053560.05156.73 |
0.329 |
|
| 2002 |
Raghuveer TS, McGuire EM, Martin SM, Wagner BA, Rebouché CJ, Buettner GR, Widness JA. Lactoferrin in the preterm infants' diet attenuates iron-induced oxidation products. Pediatric Research. 52: 964-72. PMID 12438677 DOI: 10.1203/00006450-200212000-00024 |
0.317 |
|
| 2002 |
Burns CP, Kelley EE, Wagner BA, Buettner GR. Role of nitric oxide and membrane phospholipid polyunsaturation in oxidative cell death. Sub-Cellular Biochemistry. 36: 97-121. PMID 12037992 DOI: 10.1007/0-306-47931-1_6 |
0.616 |
|
| 2002 |
Schafer FQ, Wang HP, Kelley EE, Cueno KL, Martin SM, Buettner GR. Comparing beta-carotene, vitamin E and nitric oxide as membrane antioxidants. Biological Chemistry. 383: 671-81. PMID 12033456 DOI: 10.1515/Bc.2002.069 |
0.629 |
|
| 2002 |
Zhang HJ, Zhao W, Venkataraman S, Robbins ME, Buettner GR, Kregel KC, Oberley LW. Activation of matrix metalloproteinase-2 by overexpression of manganese superoxide dismutase in human breast cancer MCF-7 cells involves reactive oxygen species. The Journal of Biological Chemistry. 277: 20919-26. PMID 11929863 DOI: 10.1074/Jbc.M109801200 |
0.324 |
|
| 2002 |
Baker MT, Gregerson MS, Martin SM, Buettner GR. Oxidation of Propofol and Lipid in Metabisulfite Containing Propofol Emulsion Anesthesiology. 96: A472. DOI: 10.1097/00000542-200209002-00472 |
0.315 |
|
| 2001 |
Yang JQ, Li S, Huang Y, Zhang HJ, Domann FE, Buettner GR, Oberley LW. V-Ha-Ras overexpression induces superoxide production and alters levels of primary antioxidant enzymes. Antioxidants & Redox Signaling. 3: 697-709. PMID 11554455 DOI: 10.1089/15230860152543032 |
0.331 |
|
| 2001 |
Zhang Y, Bissing JW, Xu L, Ryan AJ, Martin SM, Miller FJ, Kregel KC, Buettner GR, Kerber RE. Nitric oxide synthase inhibitors decrease coronary sinus-free radical concentration and ameliorate myocardial stunning in an ischemia-reperfusion model. Journal of the American College of Cardiology. 38: 546-54. PMID 11499751 DOI: 10.1016/S0735-1097(01)01400-0 |
0.31 |
|
| 2001 |
Schafer FQ, Buettner GR. Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple Free Radical Biology and Medicine. 30: 1191-1212. PMID 11368918 DOI: 10.1016/S0891-5849(01)00480-4 |
0.366 |
|
| 2001 |
Wang HP, Qian SY, Schafer FQ, Domann FE, Oberley LW, Buettner GR. Phospholipid hydroperoxide glutathione peroxidase protects against singlet oxygen-induced cell damage of photodynamic therapy. Free Radical Biology & Medicine. 30: 825-35. PMID 11295525 DOI: 10.1016/S0891-5849(01)00469-5 |
0.62 |
|
| 2000 |
Venkataraman S, Martin SM, Schafer FQ, Buettner GR. Detailed methods for the quantification of nitric oxide in aqueous solutions using either an oxygen monitor or EPR. Free Radical Biology & Medicine. 29: 580-5. PMID 11025201 DOI: 10.1016/S0891-5849(00)00404-4 |
0.33 |
|
| 2000 |
Qian SY, Wang HP, Schafer FQ, Buettner GR. EPR detection of lipid-derived free radicals from PUFA, LDL, and cell oxidations. Free Radical Biology & Medicine. 29: 568-79. PMID 11025200 DOI: 10.1016/S0891-5849(00)00407-X |
0.569 |
|
| 2000 |
Buettner GR, Schafer FQ. Free radicals, oxidants, and antioxidants Teratology. 62: 234. PMID 10992266 DOI: 10.1002/1096-9926(200010)62:4<234::Aid-Tera10>3.0.Co;2-9 |
0.305 |
|
| 2000 |
McCormick ML, Denning GM, Reszka KJ, Bilski P, Buettner GR, Rasmussen GT, Railsback MA, Britigan BE. Biological effects of menadione photochemistry: effects of menadione on biological systems may not involve classical oxidant production. The Biochemical Journal. 350: 797-804. PMID 10970795 DOI: 10.1042/0264-6021:3500797 |
0.363 |
|
| 2000 |
Liu R, Buettner GR, Oberley LW. Oxygen free radicals mediate the induction of manganese superoxide dismutase gene expression by TNF-α Free Radical Biology and Medicine. 28: 1197-1205. PMID 10889449 DOI: 10.1016/S0891-5849(00)00237-9 |
0.328 |
|
| 2000 |
Schafer FQ, Buettner GR. Acidic pH amplifies iron-mediated lipid peroxidation in cells Free Radical Biology and Medicine. 28: 1175-1181. PMID 10889446 DOI: 10.1016/S0891-5849(00)00319-1 |
0.336 |
|
| 2000 |
Schafer FQ, Qian SY, Buettner GR. Iron and free radical oxidations in cell membranes. Cellular and Molecular Biology (Noisy-Le-Grand, France). 46: 657-62. PMID 10872752 |
0.549 |
|
| 2000 |
Ridnour LA, Sim JE, Hayward MA, Wink DA, Martin SM, Buettner GR, Spitz DR. A spectrophotometric method for the direct detection and quantitation of nitric oxide, nitrite, and nitrate in cell culture media. Analytical Biochemistry. 281: 223-9. PMID 10870839 DOI: 10.1006/Abio.2000.4583 |
0.335 |
|
| 2000 |
Wagner BA, Buettner GR, Oberley LW, Darby CJ, Burns CP. Myeloperoxidase is involved in H2O2-induced apoptosis of HL-60 human leukemia cells Journal of Biological Chemistry. 275: 22461-22469. PMID 10801811 DOI: 10.1074/Jbc.M001434200 |
0.4 |
|
| 1999 |
Schafer FQ, Buettner GR. Singlet oxygen toxicity is cell line-dependent: A study of lipid peroxidation in nine leukemia cell lines Photochemistry and Photobiology. 70: 858-867. PMID 10628299 DOI: 10.1016/S0891-5849(98)90251-9 |
0.369 |
|
| 1999 |
Kelley EE, Wagner BA, Buettner GR, Burns CP. Nitric oxide inhibits iron-induced lipid peroxidation in HL-60 cells. Archives of Biochemistry and Biophysics. 370: 97-104. PMID 10496982 DOI: 10.1006/Abbi.1999.1386 |
0.645 |
|
| 1999 |
Hempel SL, Buettner GR, O'Malley YQ, Wessels DA, Flaherty DM. Dihydrofluorescein diacetate is superior for detecting intracellular oxidants: Comparison with 2',7'-dichlorodihydrofluorescein diacetate, 5(and 6)-carboxy-2',7'-dichlorodihydrofluorescein diacetate, and dihydrorhodamine 123 Free Radical Biology and Medicine. 27: 146-159. PMID 10443931 DOI: 10.1016/S0891-5849(99)00061-1 |
0.344 |
|
| 1999 |
Qian SY, Buettner GR. Iron and dioxygen chemistry is an important route to initiation of biological free radical oxidations: an electron paramagnetic resonance spin trapping study. Free Radical Biology & Medicine. 26: 1447-56. PMID 10401608 DOI: 10.1016/S0891-5849(99)00002-7 |
0.58 |
|
| 1999 |
Tapley DW, Buettner GR, Shick JM. Free radicals and chemiluminescence as products of the spontaneous oxidation of sulfide in seawater, and their biological implications Biological Bulletin. 196: 52-56. DOI: 10.2307/1543166 |
0.367 |
|
| 1999 |
Jiang X, Buettner GR, Oberley LW. Overexpression of MnSOD protects PC3 cells from cytotoxicity induced by hyperthermia Free Radical Biology and Medicine. 27: S105. DOI: 10.1016/S0891-5849(99)90861-4 |
0.33 |
|
| 1999 |
Wang H, Qian SY, Schafer F, Oberley LW, Buettner GR. Phospholipid hydroperoxide glutathione peroxidase (PhGPx) uniquely protects cell membranes from photo-oxidation Free Radical Biology and Medicine. 27: S46. DOI: 10.1016/S0891-5849(99)90652-4 |
0.585 |
|
| 1998 |
McCormick ML, Gaut JP, Lin TS, Britigan BE, Buettner GR, Heinecke JW. Electron paramagnetic resonance detection of free tyrosyl radical generated by myeloperoxidase, lactoperoxidase, and horseradish peroxidase. The Journal of Biological Chemistry. 273: 32030-7. PMID 9822676 DOI: 10.1074/Jbc.273.48.32030 |
0.343 |
|
| 1998 |
Spencer KT, Lindower PD, Buettner GR, Kerber RE. Transition metal chelators reduce directly measured myocardial free radical production during reperfusion Journal of Cardiovascular Pharmacology. 32: 343-348. PMID 9733345 DOI: 10.1097/00005344-199809000-00002 |
0.305 |
|
| 1998 |
Flanagan SW, Moseley PL, Buettner GR. Increased flux of free radicals in cells subjected to hyperthermia: Detection by electron paramagnetic resonance spin trapping Febs Letters. 431: 285-286. PMID 9708920 DOI: 10.1016/S0014-5793(98)00779-0 |
0.388 |
|
| 1998 |
McCormick ML, Buettner GR, Britigan BE. Endogenous superoxide dismutase levels regulate iron-dependent hydroxyl radical formation in Escherichia coli exposed to hydrogen peroxide. Journal of Bacteriology. 180: 622-5. PMID 9457866 DOI: 10.1128/Jb.180.3.622-625.1998 |
0.353 |
|
| 1998 |
Qian Y, Buettner GR. The EPR detection of lipid-dervied radicals during membrane lipid peroxidation of cells Free Radical Biology and Medicine. 25: S106. DOI: 10.1016/S0891-5849(98)90327-6 |
0.31 |
|
| 1998 |
Wang H, Schafer F, Kelley EE, Wagner BA, Buettner GR. β-Carotene reduces membrane damage from singlet oxygen in murine 308 epidermal cells Free Radical Biology and Medicine. 25: S102. DOI: 10.1016/S0891-5849(98)90318-5 |
0.584 |
|
| 1998 |
Schafer F, Buettner GR. Small pH changes affect iron-mediated lipid peroxidation in cells Free Radical Biology and Medicine. 25: S19. DOI: 10.1016/S0891-5849(98)90048-X |
0.3 |
|
| 1998 |
Qian Y, Buettner GR. Iron-oxygen complexes are important initiators of biological free radical oxidations Free Radical Biology and Medicine. 25: S18. DOI: 10.1016/S0891-5849(98)90045-4 |
0.334 |
|
| 1997 |
Kelley EE, Domann FE, Buettner GR, Oberley LW, Burns CP. Increased efficacy of in vitro Photofrin photosensitization of human oral squamous cell carcinoma by iron and ascorbate. Journal of Photochemistry and Photobiology. B, Biology. 40: 273-7. PMID 9372616 DOI: 10.1016/S1011-1344(97)00068-7 |
0.654 |
|
| 1997 |
Wallen ES, Buettner GR, Moseley PL. Oxidants differentially regulate the heat shock response International Journal of Hyperthermia. 13: 517-524. PMID 9354936 DOI: 10.3109/02656739709023550 |
0.312 |
|
| 1997 |
Kelley EE, Buettner GR, Burns CP. Production of lipid-derived free radicals in L1210 murine leukemia cells is an early oxidative event in the photodynamic action of Photofrin. Photochemistry and Photobiology. 65: 576-80. PMID 9077143 DOI: 10.1111/J.1751-1097.1997.Tb08608.X |
0.635 |
|
| 1997 |
Hall DM, Buettner GR, Gisolfi CV. In vivoDetection of Nitric Oxide and NOxSpecies Usingex vivoElectron Paramagnetic Resonance Spectroscopy Microchemical Journal. 56: 165-170. DOI: 10.1006/Mchj.1997.1445 |
0.355 |
|
| 1996 |
Wagner BA, Buettner GR, Burns CP. Vitamin E slows the rate of free radical-mediated lipid peroxidation in cells Archives of Biochemistry and Biophysics. 334: 261-267. PMID 8900400 DOI: 10.1006/Abbi.1996.0454 |
0.347 |
|
| 1996 |
Hall DM, Buettner GR. In vivo spin trapping of nitric oxide by heme: Electron paramagnetic resonance detection ex vivo Methods in Enzymology. 268: 188-192. PMID 8782584 DOI: 10.1016/S0076-6879(96)68020-3 |
0.303 |
|
| 1996 |
Britigan BE, Ratcliffe HR, Buettner GR, Rosen GM. Binding of myeloperoxidase to bacteria: Effect on hydroxyl radical formation and susceptibility to oxidant-mediated killing Biochimica Et Biophysica Acta - General Subjects. 1290: 231-240. PMID 8765125 DOI: 10.1016/0304-4165(96)00014-1 |
0.329 |
|
| 1996 |
Hempel SL, Buettner GR, Wessels DA, Galvan GM, O'Malley YQ. Extracellular iron(II) can protect cells from hydrogen peroxide Archives of Biochemistry and Biophysics. 330: 401-408. PMID 8660671 DOI: 10.1006/Abbi.1996.0268 |
0.347 |
|
| 1996 |
Buettner GR, Jurkiewicz BA. Catalytic metals, ascorbate and free radicals: Combinations to avoid Radiation Research. 145: 532-541. PMID 8619018 DOI: 10.2307/3579271 |
0.346 |
|
| 1995 |
Kelley EE, Buettner GR, Burns CP. Relative alpha-tocopherol deficiency in cultured cells: free radical-mediated lipid peroxidation, lipid oxidizability, and cellular polyunsaturated fatty acid content. Archives of Biochemistry and Biophysics. 319: 102-9. PMID 7771773 DOI: 10.1006/Abbi.1995.1271 |
0.626 |
|
| 1995 |
Jurkiewicz BA, Bissett DL, Buettner GR. Effect of topically applied tocopherol on ultraviolet radiation-mediated free radical damage in skin Journal of Investigative Dermatology. 104: 484-488. PMID 7706763 DOI: 10.1111/1523-1747.Ep12605921 |
0.33 |
|
| 1995 |
McCormick ML, Buettner GR, Britigan BE. The spin trap alpha-(4-pyridyl-1-oxide)-N-tert-butylnitrone stimulates peroxidase-mediated oxidation of deferoxamine. Implications for pharmacological use of spin-trapping agents. The Journal of Biological Chemistry. 270: 29265-9. PMID 7493957 DOI: 10.1074/Jbc.270.49.29265 |
0.358 |
|
| 1994 |
Wagner BA, Buettner GR, Burns CP. Free radical-mediated lipid peroxidation in cells: oxidizability is a function of cell lipid bis-allylic hydrogen content. Biochemistry. 33: 4449-53. PMID 8161499 DOI: 10.1021/Bi00181A003 |
0.348 |
|
| 1994 |
Jurkiewicz BA, Buettner GR. Ultraviolet light-induced free radical formation in skin: An electron paramagnetic resonance study Photochemistry and Photobiology. 59: 1-4. PMID 8127935 DOI: 10.1111/J.1751-1097.1994.Tb04993.X |
0.348 |
|
| 1994 |
North JA, Spector AA, Buettner GR. Cell fatty acid composition affects free radical formation during lipid peroxidation American Journal of Physiology - Cell Physiology. 267. PMID 8048478 DOI: 10.1152/Ajpcell.1994.267.1.C177 |
0.377 |
|
| 1993 |
Buettner GR. The pecking order of free radicals and antioxidants: Lipid peroxidation, α-tocopherol, and ascorbate Archives of Biochemistry and Biophysics. 300: 535-543. PMID 8434935 DOI: 10.1006/Abbi.1993.1074 |
0.305 |
|
| 1993 |
Buettner GR, Kelley EE, Burns CP. Membrane lipid free radicals produced from L1210 murine leukemia cells by photofrin photosensitization: an electron paramagnetic resonance spin trapping study. Cancer Research. 53: 3670-3. PMID 8393378 |
0.593 |
|
| 1993 |
Sharma MK, Buettner GR. Interaction of vitamin C and vitamin E during free radical stress in plasma: An ESR study Free Radical Biology and Medicine. 14: 649-653. PMID 8392021 DOI: 10.1016/0891-5849(93)90146-L |
0.336 |
|
| 1993 |
Buettner GR, Jurkiewicz BA. Ascorbate free radical as a marker of oxidative stress: An EPR study Free Radical Biology and Medicine. 14: 49-55. PMID 8384150 DOI: 10.1016/0891-5849(93)90508-R |
0.35 |
|
| 1993 |
Buettner GR, Kelley EE, Patrick Burns C. Membrane lipid free radicals produced from L1210 murine leukemia cells by photofrin photosensitization: An EPR spin trapping study Free Radical Biology and Medicine. 15: 528. DOI: 10.1016/0891-5849(93)90401-F |
0.606 |
|
| 1991 |
Britigan BE, Roeder TL, Buettner GR. Spin traps inhibit formation of hydrogen peroxide via the dismutation of superoxide: implications for spin trapping the hydroxyl free radical Bba - General Subjects. 1075: 213-222. PMID 1659450 DOI: 10.1016/0304-4165(91)90269-M |
0.356 |
|
| 1991 |
Britigan BE, Pou S, Rosen GM, LiIIeg DM, Buettner GR. Production Of Hydroxyl Radical During The Oxidation Of Xanthine By Xanthine Oxidase Is Dependent On The Presence Of Adventitious Iron Oxidative Damage & Repairchemical, Biological and Medical Aspects. 837-841. DOI: 10.1016/B978-0-08-041749-3.50150-9 |
0.341 |
|
| 1990 |
Buettner GR, Mason RP. Spin-trapping methods for detecting superoxide and hydroxyl free radicals in vitro and in vivo Methods in Enzymology. 186: 127-133. PMID 2172700 DOI: 10.1016/0076-6879(90)86101-Z |
0.327 |
|
| 1990 |
Buettner GR, Chamulitrat W. The catalytic activity of iron in synovial fluid as monitored by the ascorbate free radical Free Radical Biology and Medicine. 8: 55-56. PMID 2157634 DOI: 10.1016/0891-5849(90)90144-8 |
0.322 |
|
| 1990 |
Britigan BE, Pou S, Rosen GM, Lilleg DM, Buettner GR. Hydroxyl Radical Is Not a Product of the Reaction of Xanthine Oxidase and Xanthine Free Radical Biology and Medicine. 9: 178. DOI: 10.1016/0891-5849(90)90807-U |
0.357 |
|
| 1987 |
Hall RD, Buettner GR, Motten AG, Chignell CF. Near-infrared detection of singlet molecular oxygen produced by photosensitization with promazine and chlorpromazine Photochemistry and Photobiology. 46: 295-300. PMID 3628514 DOI: 10.1111/J.1751-1097.1987.Tb04769.X |
0.301 |
|
| 1987 |
Buettner GR, Motten AG, Hall RD, Chignell CF. ESR detection of endogenous ascorbate free radical in mouse skin: enhancement of radical production during UV irradiation following application of chlorpromazine Photochemistry and Photobiology. 46: 161-164. PMID 2819904 DOI: 10.1111/J.1751-1097.1987.Tb04751.X |
0.333 |
|
| 1986 |
Buettner GR, Motten AG, Hall RD, Chignell CF. Free radical production by chlorpromazine sulfoxide, an ESR spin-trapping and flash photolysis study Photochemistry and Photobiology. 44: 5-10. PMID 3018808 DOI: 10.1111/J.1751-1097.1986.Tb03556.X |
0.356 |
|
| 1985 |
Motten AG, Buettner GR, Chignell CF. Spectroscopic studies of cutaneous photosensitizing agents--VIII. A spin-trapping study of light induced free radicals from chlorpromazine and promazine Photochemistry and Photobiology. 42: 9-15. PMID 4059358 DOI: 10.1111/J.1751-1097.1985.Tb03540.X |
0.343 |
|
| 1985 |
Buettner GR, Need MJ. Hydrogen peroxide and hydroxyl free radical production by hematoporphyrin derivative, ascorbate and light Cancer Letters. 25: 297-304. PMID 2982479 DOI: 10.1016/S0304-3835(15)30009-4 |
0.341 |
|
| 1985 |
Chignell CF, Motten AG, Buettner GR. Photoinduced free radicals from chlorpromazine and related phenothiazines: Relationship to phenothiazine-induced photosensitization Environmental Health Perspectives. 103-110. PMID 2869942 DOI: 10.1289/Ehp.8564103 |
0.325 |
|
| 1984 |
Buettner GR. Thiyl free radical production with hematoporphyrin derivative, cysteine and light: a spin-trapping study Febs Letters. 177: 295-299. PMID 6094251 DOI: 10.1016/0014-5793(84)81303-4 |
0.336 |
|
| 1984 |
Buettner GR, Doherty TP, Bannister TD. Hydrogen peroxide and hydroxyl radical formation by methylene blue in the presence of ascorbic acid Radiation and Environmental Biophysics. 23: 235-243. PMID 6093184 DOI: 10.1007/Bf01407595 |
0.346 |
|
| 1981 |
Oberley LW, Oberley TD, Buettner GR. Cell division in normal and transformed cells: The possible role of superoxide and hydrogen peroxide Medical Hypotheses. 7: 21-42. PMID 6259499 DOI: 10.1016/0306-9877(81)90018-9 |
0.349 |
|
| 1980 |
Buettner GR, Oberley LW. The apparent production of superoxide and hydroxyl radicals by hematoporphyrin and light as seen by spin-trapping Febs Letters. 121: 161-164. PMID 6257541 DOI: 10.1016/0014-5793(80)81288-9 |
0.398 |
|
| 1980 |
Oberley LW, Oberley TD, Buettner GR. Cell differentation, aging and cancer: The possible roles of superoxide and superoxide dismutases Medical Hypotheses. 6: 249-268. PMID 6253771 DOI: 10.1016/0306-9877(80)90123-1 |
0.361 |
|
| 1979 |
Buettner GR, Oberley LW. Superoxide formation by protoporphyrin as seen by spin trapping Febs Letters. 98: 18-20. PMID 218839 DOI: 10.1016/0014-5793(79)80141-6 |
0.376 |
|
| 1979 |
Coffman RE, Buettner GR. General magnetic dipolar interaction of spin-spin coupled molecular dimers. Application to an EPR spectrum of xanthine oxidase The Journal of Physical Chemistry. 83: 2392-2400. DOI: 10.1021/J100481A018 |
0.65 |
|
| 1979 |
Coffman RE, Buettner GR. A limit function for long-range ferromagnetic and antiferromagnetic superexchange The Journal of Physical Chemistry. 83: 2387-2392. DOI: 10.1021/J100481A017 |
0.631 |
|
| 1977 |
Buettner GR, Coffman RE. EPR determination of the Co(II)-free radical magnetic geometry of the "doublet" species arising in a coenzyme B-12-enzyme reaction. Biochimica Et Biophysica Acta. 480: 495-505. PMID 189818 DOI: 10.1016/0005-2744(77)90042-0 |
0.664 |
|
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