Rita M. Cowell, Ph.D. - Publications

Affiliations: 
Psychiatry & Behavioral Neurobiology University of Alabama, Birmingham, Birmingham, AL, United States 
Area:
Interneurons, development, psychiatric/degenerative disorders
Website:
http://www.psychiatry.uab.edu/faculty/profiles/rcowell/

34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Mackenzie-Gray Scott C, Parrish RR, Walsh D, Racca C, Cowell RM, Trevelyan AJ. PV-specific loss of the transcriptional coactivator PGC-1α slows down the evolution of epileptic activity in an acute ictogenic model. Journal of Neurophysiology. 127: 86-98. PMID 34788174 DOI: 10.1152/jn.00295.2021  0.353
2021 McMeekin LJ, Joyce KL, Jenkins LM, Bohannon BM, Patel KD, Bohannon AS, Patel A, Fox SN, Simmons MS, Day JJ, Kralli A, Crossman DK, Cowell RM. Estrogen-related receptor alpha (ERRα) is required for PGC-1α-dependent gene expression in the mouse brain. Neuroscience. PMID 34648866 DOI: 10.1016/j.neuroscience.2021.10.007  0.438
2021 McMeekin LJ, Fox SN, Boas SM, Cowell RM. Dysregulation of PGC-1α-Dependent Transcriptional Programs in Neurological and Developmental Disorders: Therapeutic Challenges and Opportunities. Cells. 10. PMID 33572179 DOI: 10.3390/cells10020352  0.348
2020 McMeekin LJ, Bartley AF, Bohannon AS, Adlaf EW, van Groen T, Boas SM, Fox SN, Detloff PJ, Crossman DK, Overstreet-Wadiche LS, Hablitz JJ, Dobrunz LE, Cowell RM. A role for PGC-1α in transcription and excitability of neocortical and hippocampal excitatory neurons. Neuroscience. PMID 32222555 DOI: 10.1016/J.Neuroscience.2020.03.036  0.691
2019 Barodia SK, McMeekin LJ, Creed RB, Quinones EK, Cowell RM, Goldberg MS. PINK1 phosphorylates ubiquitin predominantly in astrocytes. Npj Parkinson's Disease. 5: 29. PMID 31840043 DOI: 10.1038/S41531-019-0101-9  0.367
2018 McMeekin LJ, Li Y, Fox SN, Rowe GC, Crossman DK, Day JJ, Li Y, Detloff PJ, Cowell RM. Cell-specific deletion of PGC-1α from medium spiny neurons causes transcriptional alterations and age-related motor impairment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29491012 DOI: 10.1523/Jneurosci.0848-17.2018  0.5
2017 Paul JR, McKeown AS, Davis JA, Totsch SK, Mintz EM, Kraft TW, Cowell RM, Gamble KL. Glycogen synthase kinase 3 regulates photic signaling in the suprachiasmatic nucleus. The European Journal of Neuroscience. PMID 28244152 DOI: 10.1111/Ejn.13549  0.336
2016 Paul JR, DeWoskin D, McMeekin LJ, Cowell RM, Forger DB, Gamble KL. Regulation of persistent sodium currents by glycogen synthase kinase 3 encodes daily rhythms of neuronal excitability. Nature Communications. 7: 13470. PMID 27841351 DOI: 10.1038/Ncomms13470  0.327
2016 Brady LJ, Bartley AF, Li Q, McMeekin LJ, Hablitz JJ, Cowell RM, Dobrunz LE. Transcriptional dysregulation causes altered modulation of inhibition by haloperidol. Neuropharmacology. PMID 27480797 DOI: 10.1016/J.Neuropharm.2016.07.034  0.685
2015 McMeekin LJ, Lucas EK, Meador-Woodruff JH, McCullumsmith RE, Hendrickson RC, Gamble KL, Cowell RM. Cortical PGC-1α-Dependent Transcripts are Reduced in Postmortem Tissue From Patients With Schizophrenia. Schizophrenia Bulletin. PMID 26683626 DOI: 10.1093/Schbul/Sbv184  0.752
2015 Bartley AF, Lucas EK, Brady LJ, Li Q, Hablitz JJ, Cowell RM, Dobrunz LE. Interneuron Transcriptional Dysregulation Causes Frequency-Dependent Alterations in the Balance of Inhibition and Excitation in Hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 15276-90. PMID 26586816 DOI: 10.1523/Jneurosci.1834-15.2015  0.78
2014 Lucas EK, Reid CS, McMeekin LJ, Dougherty SE, Floyd CL, Cowell RM. Cerebellar transcriptional alterations with Purkinje cell dysfunction and loss in mice lacking PGC-1α. Frontiers in Cellular Neuroscience. 8: 441. PMID 25610371 DOI: 10.3389/Fncel.2014.00441  0.75
2014 Lucas EK, Dougherty SE, McMeekin LJ, Reid CS, Dobrunz LE, West AB, Hablitz JJ, Cowell RM. PGC-1α provides a transcriptional framework for synchronous neurotransmitter release from parvalbumin-positive interneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 14375-87. PMID 25339750 DOI: 10.1523/Jneurosci.1222-14.2014  0.755
2014 Dougherty SE, Bartley AF, Lucas EK, Hablitz JJ, Dobrunz LE, Cowell RM. Mice lacking the transcriptional coactivator PGC-1α exhibit alterations in inhibitory synaptic transmission in the motor cortex. Neuroscience. 271: 137-48. PMID 24769433 DOI: 10.1016/J.Neuroscience.2014.04.023  0.765
2014 West AB, Cowell RM, Daher JP, Moehle MS, Hinkle KM, Melrose HL, Standaert DG, Volpicelli-Daley LA. Differential LRRK2 expression in the cortex, striatum, and substantia nigra in transgenic and nontransgenic rodents. The Journal of Comparative Neurology. 522: 2465-80. PMID 24633735 DOI: 10.1002/Cne.23583  0.404
2014 Dougherty SE, Hollimon JJ, McMeekin LJ, Bohannon AS, West AB, Lesort M, Hablitz JJ, Cowell RM. Hyperactivity and cortical disinhibition in mice with restricted expression of mutant huntingtin to parvalbumin-positive cells. Neurobiology of Disease. 62: 160-71. PMID 24121117 DOI: 10.1016/J.Nbd.2013.10.002  0.79
2013 Jiang Z, Rompala GR, Zhang S, Cowell RM, Nakazawa K. Social isolation exacerbates schizophrenia-like phenotypes via oxidative stress in cortical interneurons. Biological Psychiatry. 73: 1024-34. PMID 23348010 DOI: 10.1016/J.Biopsych.2012.12.004  0.349
2013 Dougherty SE, Reeves JL, Lesort M, Detloff PJ, Cowell RM. Purkinje cell dysfunction and loss in a knock-in mouse model of Huntington disease. Experimental Neurology. 240: 96-102. PMID 23195593 DOI: 10.1016/J.Expneurol.2012.11.015  0.757
2013 Cowell RM, Russell JW. Peripheral Neuropathy and the Schwann Cell Neuroglia. DOI: 10.1093/acprof:oso/9780195152227.003.0046  0.408
2012 Lucas EK, Dougherty SE, McMeekin LJ, Trinh AT, Reid CS, Cowell RM. Developmental alterations in motor coordination and medium spiny neuron markers in mice lacking pgc-1α. Plos One. 7: e42878. PMID 22916173 DOI: 10.1371/Journal.Pone.0042878  0.775
2012 Dougherty SE, Reeves JL, Lucas EK, Gamble KL, Lesort M, Cowell RM. Disruption of Purkinje cell function prior to huntingtin accumulation and cell loss in an animal model of Huntington disease. Experimental Neurology. 236: 171-8. PMID 22579526 DOI: 10.1016/J.Expneurol.2012.04.015  0.749
2012 Moehle MS, Webber PJ, Tse T, Sukar N, Standaert DG, DeSilva TM, Cowell RM, West AB. LRRK2 inhibition attenuates microglial inflammatory responses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 1602-11. PMID 22302802 DOI: 10.1523/Jneurosci.5601-11.2012  0.331
2010 Ma D, Li S, Lucas EK, Cowell RM, Lin JD. Neuronal inactivation of peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) protects mice from diet-induced obesity and leads to degenerative lesions. The Journal of Biological Chemistry. 285: 39087-95. PMID 20947495 DOI: 10.1074/Jbc.M110.151688  0.752
2010 Lucas EK, Markwardt SJ, Gupta S, Meador-Woodruff JH, Lin JD, Overstreet-Wadiche L, Cowell RM. Parvalbumin deficiency and GABAergic dysfunction in mice lacking PGC-1alpha. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 7227-35. PMID 20505089 DOI: 10.1523/Jneurosci.0698-10.2010  0.75
2009 Cowell RM, Talati P, Blake KR, Meador-Woodruff JH, Russell JW. Identification of novel targets for PGC-1alpha and histone deacetylase inhibitors in neuroblastoma cells. Biochemical and Biophysical Research Communications. 379: 578-82. PMID 19118529 DOI: 10.1016/J.Bbrc.2008.12.109  0.584
2008 Cowell RM, Blake KR, Inoue T, Russell JW. Regulation of PGC-1alpha and PGC-1alpha-responsive genes with forskolin-induced Schwann cell differentiation. Neuroscience Letters. 439: 269-74. PMID 18538475 DOI: 10.1016/J.Neulet.2008.04.104  0.559
2007 Cowell RM, Blake KR, Russell JW. Localization of the transcriptional coactivator PGC-1alpha to GABAergic neurons during maturation of the rat brain. The Journal of Comparative Neurology. 502: 1-18. PMID 17335037 DOI: 10.1002/Cne.21211  0.597
2006 Cowell RM, Xu H, Parent JM, Silverstein FS. Microglial expression of chemokine receptor CCR5 during rat forebrain development and after perinatal hypoxia-ischemia. Journal of Neuroimmunology. 173: 155-65. PMID 16516309 DOI: 10.1016/J.Jneuroim.2006.01.005  0.6
2004 Cowell RM, Russell JW. Nitrosative injury and antioxidant therapy in the management of diabetic neuropathy. Journal of Investigative Medicine : the Official Publication of the American Federation For Clinical Research. 52: 33-44. PMID 14989368 DOI: 10.1136/Jim-52-01-24  0.509
2003 Cowell RM, Plane JM, Silverstein FS. Complement activation contributes to hypoxic-ischemic brain injury in neonatal rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9459-68. PMID 14561876 DOI: 10.1523/Jneurosci.23-28-09459.2003  0.552
2003 Cowell RM, Silverstein FS. Developmental changes in the expression of chemokine receptor CCR1 in the rat cerebellum. The Journal of Comparative Neurology. 457: 7-23. PMID 12541321 DOI: 10.1002/Cne.10554  0.629
2002 Cowell RM, Xu H, Galasso JM, Silverstein FS. Hypoxic-ischemic injury induces macrophage inflammatory protein-1alpha expression in immature rat brain. Stroke; a Journal of Cerebral Circulation. 33: 795-801. PMID 11872906 DOI: 10.1161/Hs0302.103740  0.598
2000 Galasso JM, Miller MJ, Cowell RM, Harrison JK, Warren JS, Silverstein FS. Acute excitotoxic injury induces expression of monocyte chemoattractant protein-1 and its receptor, CCR2, in neonatal rat brain. Experimental Neurology. 165: 295-305. PMID 10993690 DOI: 10.1006/Exnr.2000.7466  0.573
1998 Klintsova AY, Cowell RM, Swain RA, Napper RM, Goodlett CR, Greenough WT. Therapeutic effects of complex motor training on motor performance deficits induced by neonatal binge-like alcohol exposure in rats . I. Behavioral results. Brain Research. 800: 48-61. PMID 9685583 DOI: 10.1016/S0006-8993(98)00495-8  0.52
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