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Rita M. Cowell, Ph.D. - Publications

Affiliations: 
Psychiatry & Behavioral Neurobiology University of Alabama, Birmingham, Birmingham, AL, United States 
Area:
Interneurons, development, psychiatric/degenerative disorders
Website:
http://www.psychiatry.uab.edu/faculty/profiles/rcowell/
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38/55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Singh M, Sapkota K, Sakimura K, Kano M, Cowell RM, Overstreet-Wadiche L, Hablitz JJ, Nakazawa K. Maturation of GABAergic Synaptic Transmission from Neocortical Parvalbumin Interneurons Involves NMDA receptor Recruitment of Cav2.1 Channels. Neuroscience. PMID 36682446 DOI: 10.1016/j.neuroscience.2023.01.007  0.563
2022 Fox SN, McMeekin LJ, Savage CH, Joyce KL, Boas SM, Simmons MS, Farmer CB, Ryan J, Pereboeva L, Becker K, Auwerx J, Sudarshan S, Ma J, Lee A, Roberts RC, ... ... Cowell RM, et al. Estrogen-related receptor gamma regulates mitochondrial and synaptic genes and modulates vulnerability to synucleinopathy. Npj Parkinson's Disease. 8: 106. PMID 35982091 DOI: 10.1038/s41531-022-00369-w  0.335
2022 McMeekin LJ, Joyce KL, Jenkins LM, Bohannon BM, Patel KD, Bohannon AS, Patel A, Fox SN, Simmons MS, Day JJ, Kralli A, Crossman DK, Cowell RM. Corrigendum to "Estrogen-related Receptor Alpha (ERRα) is Required for PGC-1α-dependent Gene Expression in the Mouse Brain" [Neuroscience 479 (2021) 70-90]. Neuroscience. 493: 119. PMID 35594912 DOI: 10.1016/j.neuroscience.2022.05.011  0.303
2022 Mackenzie-Gray Scott C, Parrish RR, Walsh D, Racca C, Cowell RM, Trevelyan AJ. PV-specific loss of the transcriptional coactivator PGC-1α slows down the evolution of epileptic activity in an acute ictogenic model. Journal of Neurophysiology. 127: 86-98. PMID 34788174 DOI: 10.1152/jn.00295.2021  0.363
2021 McMeekin LJ, Joyce KL, Jenkins LM, Bohannon BM, Patel KD, Bohannon AS, Patel A, Fox SN, Simmons MS, Day JJ, Kralli A, Crossman DK, Cowell RM. Estrogen-related receptor alpha (ERRα) is required for PGC-1α-dependent gene expression in the mouse brain. Neuroscience. PMID 34648866 DOI: 10.1016/j.neuroscience.2021.10.007  0.45
2021 Fusilier AR, Davis JA, Paul JR, Yates SD, McMeekin LJ, Goode LK, Mokashi MV, Remiszewski N, van Groen T, Cowell RM, McMahon LL, Roberson ED, Gamble KL. Dysregulated clock gene expression and abnormal diurnal regulation of hippocampal inhibitory transmission and spatial memory in a mouse model of Alzheimer's disease. Neurobiology of Disease. 105454. PMID 34333153 DOI: 10.1016/j.nbd.2021.105454  0.554
2021 McMeekin LJ, Fox SN, Boas SM, Cowell RM. Dysregulation of PGC-1α-Dependent Transcriptional Programs in Neurological and Developmental Disorders: Therapeutic Challenges and Opportunities. Cells. 10. PMID 33572179 DOI: 10.3390/cells10020352  0.733
2020 McMeekin LJ, Bartley AF, Bohannon AS, Adlaf EW, van Groen T, Boas SM, Fox SN, Detloff PJ, Crossman DK, Overstreet-Wadiche LS, Hablitz JJ, Dobrunz LE, Cowell RM. A role for PGC-1α in transcription and excitability of neocortical and hippocampal excitatory neurons. Neuroscience. PMID 32222555 DOI: 10.1016/J.Neuroscience.2020.03.036  0.7
2019 Barodia SK, McMeekin LJ, Creed RB, Quinones EK, Cowell RM, Goldberg MS. PINK1 phosphorylates ubiquitin predominantly in astrocytes. Npj Parkinson's Disease. 5: 29. PMID 31840043 DOI: 10.1038/S41531-019-0101-9  0.376
2018 McMeekin LJ, Li Y, Fox SN, Rowe GC, Crossman DK, Day JJ, Li Y, Detloff PJ, Cowell RM. Cell-specific deletion of PGC-1α from medium spiny neurons causes transcriptional alterations and age-related motor impairment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29491012 DOI: 10.1523/Jneurosci.0848-17.2018  0.764
2017 Paul JR, McKeown AS, Davis JA, Totsch SK, Mintz EM, Kraft TW, Cowell RM, Gamble KL. Glycogen synthase kinase 3 regulates photic signaling in the suprachiasmatic nucleus. The European Journal of Neuroscience. PMID 28244152 DOI: 10.1111/Ejn.13549  0.336
2016 Paul JR, DeWoskin D, McMeekin LJ, Cowell RM, Forger DB, Gamble KL. Regulation of persistent sodium currents by glycogen synthase kinase 3 encodes daily rhythms of neuronal excitability. Nature Communications. 7: 13470. PMID 27841351 DOI: 10.1038/Ncomms13470  0.335
2016 Brady LJ, Bartley AF, Li Q, McMeekin LJ, Hablitz JJ, Cowell RM, Dobrunz LE. Transcriptional dysregulation causes altered modulation of inhibition by haloperidol. Neuropharmacology. PMID 27480797 DOI: 10.1016/J.Neuropharm.2016.07.034  0.689
2015 McMeekin LJ, Lucas EK, Meador-Woodruff JH, McCullumsmith RE, Hendrickson RC, Gamble KL, Cowell RM. Cortical PGC-1α-Dependent Transcripts are Reduced in Postmortem Tissue From Patients With Schizophrenia. Schizophrenia Bulletin. PMID 26683626 DOI: 10.1093/Schbul/Sbv184  0.748
2015 Bartley AF, Lucas EK, Brady LJ, Li Q, Hablitz JJ, Cowell RM, Dobrunz LE. Interneuron Transcriptional Dysregulation Causes Frequency-Dependent Alterations in the Balance of Inhibition and Excitation in Hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 15276-90. PMID 26586816 DOI: 10.1523/Jneurosci.1834-15.2015  0.781
2014 Lucas EK, Reid CS, McMeekin LJ, Dougherty SE, Floyd CL, Cowell RM. Cerebellar transcriptional alterations with Purkinje cell dysfunction and loss in mice lacking PGC-1α. Frontiers in Cellular Neuroscience. 8: 441. PMID 25610371 DOI: 10.3389/Fncel.2014.00441  0.755
2014 Lucas EK, Dougherty SE, McMeekin LJ, Reid CS, Dobrunz LE, West AB, Hablitz JJ, Cowell RM. PGC-1α provides a transcriptional framework for synchronous neurotransmitter release from parvalbumin-positive interneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 14375-87. PMID 25339750 DOI: 10.1523/Jneurosci.1222-14.2014  0.768
2014 Dougherty SE, Bartley AF, Lucas EK, Hablitz JJ, Dobrunz LE, Cowell RM. Mice lacking the transcriptional coactivator PGC-1α exhibit alterations in inhibitory synaptic transmission in the motor cortex. Neuroscience. 271: 137-48. PMID 24769433 DOI: 10.1016/J.Neuroscience.2014.04.023  0.775
2014 West AB, Cowell RM, Daher JP, Moehle MS, Hinkle KM, Melrose HL, Standaert DG, Volpicelli-Daley LA. Differential LRRK2 expression in the cortex, striatum, and substantia nigra in transgenic and nontransgenic rodents. The Journal of Comparative Neurology. 522: 2465-80. PMID 24633735 DOI: 10.1002/Cne.23583  0.402
2014 Dougherty SE, Hollimon JJ, McMeekin LJ, Bohannon AS, West AB, Lesort M, Hablitz JJ, Cowell RM. Hyperactivity and cortical disinhibition in mice with restricted expression of mutant huntingtin to parvalbumin-positive cells. Neurobiology of Disease. 62: 160-71. PMID 24121117 DOI: 10.1016/J.Nbd.2013.10.002  0.793
2013 Jiang Z, Rompala GR, Zhang S, Cowell RM, Nakazawa K. Social isolation exacerbates schizophrenia-like phenotypes via oxidative stress in cortical interneurons. Biological Psychiatry. 73: 1024-34. PMID 23348010 DOI: 10.1016/J.Biopsych.2012.12.004  0.344
2013 Dougherty SE, Reeves JL, Lesort M, Detloff PJ, Cowell RM. Purkinje cell dysfunction and loss in a knock-in mouse model of Huntington disease. Experimental Neurology. 240: 96-102. PMID 23195593 DOI: 10.1016/J.Expneurol.2012.11.015  0.757
2013 Cowell RM, Russell JW. Peripheral Neuropathy and the Schwann Cell Neuroglia. DOI: 10.1093/acprof:oso/9780195152227.003.0046  0.4
2012 Lucas EK, Dougherty SE, McMeekin LJ, Trinh AT, Reid CS, Cowell RM. Developmental alterations in motor coordination and medium spiny neuron markers in mice lacking pgc-1α. Plos One. 7: e42878. PMID 22916173 DOI: 10.1371/Journal.Pone.0042878  0.782
2012 Dougherty SE, Reeves JL, Lucas EK, Gamble KL, Lesort M, Cowell RM. Disruption of Purkinje cell function prior to huntingtin accumulation and cell loss in an animal model of Huntington disease. Experimental Neurology. 236: 171-8. PMID 22579526 DOI: 10.1016/J.Expneurol.2012.04.015  0.755
2012 Moehle MS, Webber PJ, Tse T, Sukar N, Standaert DG, DeSilva TM, Cowell RM, West AB. LRRK2 inhibition attenuates microglial inflammatory responses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 1602-11. PMID 22302802 DOI: 10.1523/Jneurosci.5601-11.2012  0.33
2010 Ma D, Li S, Lucas EK, Cowell RM, Lin JD. Neuronal inactivation of peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) protects mice from diet-induced obesity and leads to degenerative lesions. The Journal of Biological Chemistry. 285: 39087-95. PMID 20947495 DOI: 10.1074/Jbc.M110.151688  0.745
2010 Lucas EK, Markwardt SJ, Gupta S, Meador-Woodruff JH, Lin JD, Overstreet-Wadiche L, Cowell RM. Parvalbumin deficiency and GABAergic dysfunction in mice lacking PGC-1alpha. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 7227-35. PMID 20505089 DOI: 10.1523/Jneurosci.0698-10.2010  0.741
2009 Cowell RM, Talati P, Blake KR, Meador-Woodruff JH, Russell JW. Identification of novel targets for PGC-1alpha and histone deacetylase inhibitors in neuroblastoma cells. Biochemical and Biophysical Research Communications. 379: 578-82. PMID 19118529 DOI: 10.1016/J.Bbrc.2008.12.109  0.581
2008 Cowell RM, Blake KR, Inoue T, Russell JW. Regulation of PGC-1alpha and PGC-1alpha-responsive genes with forskolin-induced Schwann cell differentiation. Neuroscience Letters. 439: 269-74. PMID 18538475 DOI: 10.1016/J.Neulet.2008.04.104  0.553
2007 Cowell RM, Blake KR, Russell JW. Localization of the transcriptional coactivator PGC-1alpha to GABAergic neurons during maturation of the rat brain. The Journal of Comparative Neurology. 502: 1-18. PMID 17335037 DOI: 10.1002/Cne.21211  0.591
2006 Cowell RM, Xu H, Parent JM, Silverstein FS. Microglial expression of chemokine receptor CCR5 during rat forebrain development and after perinatal hypoxia-ischemia. Journal of Neuroimmunology. 173: 155-65. PMID 16516309 DOI: 10.1016/J.Jneuroim.2006.01.005  0.597
2004 Cowell RM, Russell JW. Nitrosative injury and antioxidant therapy in the management of diabetic neuropathy. Journal of Investigative Medicine : the Official Publication of the American Federation For Clinical Research. 52: 33-44. PMID 14989368 DOI: 10.1136/Jim-52-01-24  0.505
2003 Cowell RM, Plane JM, Silverstein FS. Complement activation contributes to hypoxic-ischemic brain injury in neonatal rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9459-68. PMID 14561876 DOI: 10.1523/Jneurosci.23-28-09459.2003  0.551
2003 Cowell RM, Silverstein FS. Developmental changes in the expression of chemokine receptor CCR1 in the rat cerebellum. The Journal of Comparative Neurology. 457: 7-23. PMID 12541321 DOI: 10.1002/Cne.10554  0.626
2002 Cowell RM, Xu H, Galasso JM, Silverstein FS. Hypoxic-ischemic injury induces macrophage inflammatory protein-1alpha expression in immature rat brain. Stroke; a Journal of Cerebral Circulation. 33: 795-801. PMID 11872906 DOI: 10.1161/Hs0302.103740  0.595
2000 Galasso JM, Miller MJ, Cowell RM, Harrison JK, Warren JS, Silverstein FS. Acute excitotoxic injury induces expression of monocyte chemoattractant protein-1 and its receptor, CCR2, in neonatal rat brain. Experimental Neurology. 165: 295-305. PMID 10993690 DOI: 10.1006/Exnr.2000.7466  0.571
1998 Klintsova AY, Cowell RM, Swain RA, Napper RM, Goodlett CR, Greenough WT. Therapeutic effects of complex motor training on motor performance deficits induced by neonatal binge-like alcohol exposure in rats . I. Behavioral results. Brain Research. 800: 48-61. PMID 9685583 DOI: 10.1016/S0006-8993(98)00495-8  0.519
Low-probability matches (unlikely to be authored by this person)
2013 Jiang Z, Cowell RM, Nakazawa K. Convergence of genetic and environmental factors on parvalbumin-positive interneurons in schizophrenia. Frontiers in Behavioral Neuroscience. 7: 116. PMID 24027504 DOI: 10.3389/Fnbeh.2013.00116  0.294
2021 Sargent D, Cunningham LA, Dues DJ, Ma Y, Kordich JJ, Mercado G, Brundin P, Cowell RM, Moore DJ. Neuronal deletion induces spinal cord motor neuron degeneration and early post-natal lethality. Brain Communications. 3: fcab208. PMID 34704029 DOI: 10.1093/braincomms/fcab208  0.29
2013 Fraser KB, Moehle MS, Daher JP, Webber PJ, Williams JY, Stewart CA, Yacoubian TA, Cowell RM, Dokland T, Ye T, Chen D, Siegal GP, Galemmo RA, Tsika E, Moore DJ, et al. LRRK2 secretion in exosomes is regulated by 14-3-3. Human Molecular Genetics. 22: 4988-5000. PMID 23886663 DOI: 10.1093/Hmg/Ddt346  0.285
2019 Barodia SK, McMeekin LJ, Creed RB, Quinones EK, Cowell RM, Goldberg MS. PINK1 phosphorylates ubiquitin predominantly in astrocytes. Npj Parkinson's Disease. 5: 29. PMID 33298973 DOI: 10.1038/s41531-019-0101-9  0.256
2013 Davies P, Hinkle KM, Sukar NN, Sepulveda B, Mesias R, Serrano G, Alessi DR, Beach TG, Benson DL, White CL, Cowell RM, Das SS, West AB, Melrose HL. Comprehensive characterization and optimization of anti-LRRK2 (leucine-rich repeat kinase 2) monoclonal antibodies. The Biochemical Journal. 453: 101-13. PMID 23560750 DOI: 10.1042/Bj20121742  0.255
2017 Totsch SK, Quinn TL, Strath LJ, McMeekin LJ, Cowell RM, Gower BA, Sorge RE. The impact of the Standard American Diet in rats: Effects on behavior, physiology and recovery from inflammatory injury. Scandinavian Journal of Pain. PMID 28927908 DOI: 10.1016/J.Sjpain.2017.08.009  0.25
2021 Boas SM, Joyce KL, Cowell RM. The NRF2-Dependent Transcriptional Regulation of Antioxidant Defense Pathways: Relevance for Cell Type-Specific Vulnerability to Neurodegeneration and Therapeutic Intervention. Antioxidants (Basel, Switzerland). 11. PMID 35052512 DOI: 10.3390/antiox11010008  0.24
2000 Cowell RM, Kantor L, Hewlett GH, Frey KA, Gnegy ME. Dopamine transporter antagonists block phorbol ester-induced dopamine release and dopamine transporter phosphorylation in striatal synaptosomes. European Journal of Pharmacology. 389: 59-65. PMID 10686296 DOI: 10.1016/S0014-2999(99)00828-6  0.223
2021 Gcwensa NZ, Russell DL, Cowell RM, Volpicelli-Daley LA. Molecular Mechanisms Underlying Synaptic and Axon Degeneration in Parkinson's Disease. Frontiers in Cellular Neuroscience. 15: 626128. PMID 33737866 DOI: 10.3389/fncel.2021.626128  0.207
2021 Marcus JM, Hossain MI, Gagné JP, Poirier GG, McMahon LL, Cowell RM, Andrabi SA. PARP-1 activation leads to cytosolic accumulation of TDP-43 in neurons. Neurochemistry International. 148: 105077. PMID 34082062 DOI: 10.1016/j.neuint.2021.105077  0.178
2021 Marcus JM, Hossain MI, Gagné JP, Poirier GG, McMahon LL, Cowell RM, Andrabi SA. PARP-1 activation leads to cytosolic accumulation of TDP-43 in neurons. Neurochemistry International. 148: 105077. PMID 34082062 DOI: 10.1016/j.neuint.2021.105077  0.178
2023 Davis SE, Cook AK, Hall JA, Voskobiynyk Y, Carullo NV, Boyle NR, Hakim AR, Anderson KM, Hobdy KP, Pugh DA, Murchison CF, McMeekin LJ, Simmons M, Margolies KA, Cowell RM, et al. Patients with sporadic FTLD exhibit similar increases in lysosomal proteins and storage material as patients with FTD due to GRN mutations. Acta Neuropathologica Communications. 11: 70. PMID 37118844 DOI: 10.1186/s40478-023-01571-4  0.162
2020 Davis JA, Paul JR, McMeekin LJ, Nason SR, Antipenko JP, Yates SD, Cowell RM, Habegger KM, Gamble KL. High-Fat and High-Sucrose Diets Impair Time-of-Day Differences in Spatial Working Memory of Male Mice. Obesity (Silver Spring, Md.). PMID 33043637 DOI: 10.1002/oby.22983  0.161
2020 Mathew B, Ruiz P, Dutta S, Entrekin JT, Zhang S, Patel KD, Simmons MS, Augelli-Szafran CE, Cowell RM, Suto MJ. Structure-activity relationship (SAR) studies of N-(3-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine (SRI-22819) as NF-ҡB activators for the treatment of ALS. European Journal of Medicinal Chemistry. 112952. PMID 33139114 DOI: 10.1016/j.ejmech.2020.112952  0.155
2022 Ghajar-Rahimi G, Traylor AM, Mathew B, Bostwick JR, Nebane NM, Zmijewska AA, Esman SK, Thukral S, Zhai L, Sambandam V, Cowell RM, Suto MJ, George JF, Augelli-Szafran CE, Agarwal A. Identification of Cytoprotective Small-Molecule Inducers of Heme-Oxygenase-1. Antioxidants (Basel, Switzerland). 11. PMID 36290611 DOI: 10.3390/antiox11101888  0.151
2020 Schoonover KE, McMeekin LJ, Farmer CB, Varghese NE, Queern SL, Lapi SE, Cowell RM, Roberts RC. Interactions between knockout of schizophrenia risk factor dysbindin-1 and copper metabolism in mice. Brain Research Bulletin. PMID 32795490 DOI: 10.1016/J.Brainresbull.2020.07.024  0.127
2016 Waite M, Totsch S, Quinn T, Tomkovich A, Schumann A, Miller K, Cowell R, Sorge R. (303) Sex differences in the impact of the suboptimal American diet in rats: effects on behavior, physiology and recovery. The Journal of Pain : Official Journal of the American Pain Society. 17: S51-S52. PMID 28162541 DOI: 10.1016/j.jpain.2016.01.210  0.074
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