| Year |
Citation |
Score |
| 2021 |
Garai S, Schaffer PC, Laprairie RB, Janero DR, Pertwee RG, Straiker A, Thakur GA. Design, synthesis, and pharmacological profiling of cannabinoid 1 receptor allosteric modulators: Preclinical efficacy of C2-group GAT211 congeners for reducing intraocular pressure. Bioorganic & Medicinal Chemistry. 50: 116421. PMID 34634617 DOI: 10.1016/j.bmc.2021.116421 |
0.371 |
|
| 2021 |
Pismataro MC, Horenstein NA, Stokes C, Dallanoce C, Thakur GA, Papke RL. Stable desensitization of α nicotinic acetylcholine receptors by NS6740 requires interaction with S36 in the orthosteric agonist binding site. European Journal of Pharmacology. 905: 174179. PMID 34004208 DOI: 10.1016/j.ejphar.2021.174179 |
0.422 |
|
| 2021 |
Mizrachi T, Marsha O, Brusin K, Ben-David Y, Thakur GA, Vaknin-Dembinsky A, Treinin M, Brenner T. Suppression of neuroinflammation by an allosteric agonist and positive allosteric modulator of the α7 nicotinic acetylcholine receptor GAT107. Journal of Neuroinflammation. 18: 99. PMID 33902624 DOI: 10.1186/s12974-021-02149-4 |
0.323 |
|
| 2021 |
Garai S, Leo LM, Szczesniak AM, Hurst DP, Schaffer PC, Zagzoog A, Black T, Deschamps JR, Miess E, Schulz S, Janero DR, Straiker A, Pertwee RG, Abood ME, Kelly MEM, ... ... Thakur GA, et al. Discovery of a Biased Allosteric Modulator for Cannabinoid 1 Receptor: Preclinical Anti-Glaucoma Efficacy. Journal of Medicinal Chemistry. PMID 33826336 DOI: 10.1021/acs.jmedchem.1c00040 |
0.358 |
|
| 2021 |
Jiang S, Iliopoulos-Tsoutsouvas C, Tong F, Brust CA, Keenan CM, Raghav JG, Hua T, Wu S, Ho JH, Wu Y, Grim TW, Zvonok N, Thakur GA, Liu ZJ, Sharkey KA, et al. Novel Functionalized Cannabinoid Receptor Probes: Development of Exceptionally Potent Agonists. Journal of Medicinal Chemistry. PMID 33761251 DOI: 10.1021/acs.jmedchem.0c02053 |
0.387 |
|
| 2021 |
McElroy DL, Roebuck AJ, Scott GA, Greba Q, Garai S, Denovan-Wright EM, Thakur GA, Laprairie RB, Howland JG. Antipsychotic potential of the type 1 cannabinoid receptor positive allosteric modulator GAT211: preclinical in vitro and in vivo studies. Psychopharmacology. PMID 33442771 DOI: 10.1007/s00213-020-05755-x |
0.357 |
|
| 2020 |
Schaffer PC, Kulkarni PM, Janero DR, Thakur GA. Focused structure-activity relationship profiling around the 2-phenylindole scaffold of a cannabinoid type-1 receptor agonist-positive allosteric modulator: site-III aromatic-ring congeners with enhanced activity and solubility. Bioorganic & Medicinal Chemistry. 28: 115727. PMID 33065437 DOI: 10.1016/j.bmc.2020.115727 |
0.345 |
|
| 2020 |
Papke RL, Garai S, Stokes C, Horenstein NA, Zimmerman AD, Abboud KA, Thakur GA. Differing activity profiles of the stereoisomers of 2,3,5,6TMP-TQS, a putative silent allosteric modulator of α7nAChR. Molecular Pharmacology. PMID 32690627 DOI: 10.1124/Mol.120.119958 |
0.384 |
|
| 2020 |
Thapa D, Cairns EA, Szczesniak AM, Kulkarni PM, Straiker AJ, Thakur GA, Kelly MEM. Allosteric Cannabinoid Receptor 1 (CB1) Ligands Reduce Ocular Pain and Inflammation. Molecules (Basel, Switzerland). 25. PMID 31968549 DOI: 10.3390/molecules25020417 |
0.475 |
|
| 2019 |
Garai S, Kulkarni PM, Schaffer PC, Leo L, Brandt AL, Zagzoog A, Black T, Lin X, Hurst DP, Janero DR, Abood ME, Zimmowitch A, Straiker A, Pertwee RG, Kelly M, ... ... Thakur GA, et al. Application of Fluorine- And Nitrogen-Walk Approaches: Defining the Structural and Functional Diversity of 2-Phenylindole Class of CB1 Receptor Positive Allosteric Modulators. Journal of Medicinal Chemistry. PMID 31756109 DOI: 10.1021/Acs.Jmedchem.9B01142 |
0.445 |
|
| 2019 |
Laprairie RB, Mohamed KA, Zagzoog A, Kelly MEM, Stevenson LA, Pertwee R, Denovan-Wright EM, Thakur GA. Indomethacin Enhances Type 1 Cannabinoid Receptor Signaling. Frontiers in Molecular Neuroscience. 12: 257. PMID 31680861 DOI: 10.3389/Fnmol.2019.00257 |
0.369 |
|
| 2019 |
Salaga M, Binienda A, Tichkule RB, Thakur GA, Makriyannis A, Storr M, Fichna J. Corrigendum to "The novel peripherally active cannabinoid type 1 and serotonin type 3 receptor agonist AM9405 inhibits gastrointestinal motility and reduces abdominal pain in mouse models mimicking irritable bowel syndrome" [Eur. J. Pharmacol. (2018), 836 34-43]. European Journal of Pharmacology. 172656. PMID 31519354 DOI: 10.1016/J.Ejphar.2019.172656 |
0.719 |
|
| 2019 |
Hurst DP, Garai S, Kulkarni PM, Schaffer PC, Reggio PH, Thakur GA. Identification of CB1 Receptor Allosteric Sites Using Force-Biased MMC Simulated Annealing and Validation by Structure-Activity Relationship Studies. Acs Medicinal Chemistry Letters. 10: 1216-1221. PMID 31413808 DOI: 10.1021/acsmedchemlett.9b00256 |
0.381 |
|
| 2019 |
Gulsevin A, Papke RL, Stokes C, Thakur GA, Quadri M, Horenstein N. Allosteric agonism of α7 nicotinic acetylcholine receptors. Molecular Pharmacology. PMID 30944209 DOI: 10.1124/Mol.119.115758 |
0.347 |
|
| 2019 |
Laprairie RB, Bagher AM, Rourke JL, Zrein A, Cairns EA, Kelly MEM, Sinal CJ, Kulkarni PM, Thakur GA, Denovan-Wright EM. Positive allosteric modulation of the type 1 cannabinoid receptor reduces the signs and symptoms of Huntington's disease in the R6/2 mouse model. Neuropharmacology. PMID 30940536 DOI: 10.1016/J.Neuropharm.2019.03.033 |
0.32 |
|
| 2018 |
Salaga M, Binienda A, Tichkule RB, Thakur GA, Makriyannis A, Storr M, Fichna J. The novel peripherally active cannabinoid type 1 and serotonin type 3 receptor agonist AM9405 inhibits gastrointestinal motility and reduces abdominal pain in mouse models mimicking irritable bowel syndrome. European Journal of Pharmacology. PMID 30121173 DOI: 10.1016/J.Ejphar.2018.08.016 |
0.731 |
|
| 2017 |
Mitjavila J, Yin D, Kulkarni PM, Zanato C, Thakur GA, Ross R, Greig I, Mackie K, Straiker A. Enantiomer-specific positive allosteric modulation of CB1 signaling in autaptic hippocampal neurons. Pharmacological Research. PMID 29158048 DOI: 10.1016/j.phrs.2017.11.019 |
0.315 |
|
| 2017 |
Slivicki RA, Xu Z, Kulkarni PM, Pertwee RG, Mackie K, Thakur GA, Hohmann AG. Positive Allosteric Modulation of Cannabinoid Receptor Type 1 Suppresses Pathological Pain Without Producing Tolerance or Dependence. Biological Psychiatry. PMID 28823711 DOI: 10.1016/J.Biopsych.2017.06.032 |
0.464 |
|
| 2017 |
Kulkarni AR, Garai S, Janero DR, Thakur GA. Design and Synthesis of Cannabinoid 1 Receptor (CB1R) Allosteric Modulators: Drug Discovery Applications. Methods in Enzymology. 593: 281-315. PMID 28750808 DOI: 10.1016/bs.mie.2017.06.018 |
0.456 |
|
| 2017 |
Cairns EA, Szczesniak AM, Straiker AJ, Kulkarni PM, Pertwee RG, Thakur GA, Baldridge WH, Kelly MEM. The In Vivo Effects of the CB1-Positive Allosteric Modulator GAT229 on Intraocular Pressure in Ocular Normotensive and Hypertensive Mice. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. PMID 28719234 DOI: 10.1089/jop.2017.0037 |
0.367 |
|
| 2017 |
Donvito G, Bagdas D, Toma W, Rahimpour E, Jackson A, Meade JA, AlSharari S, Kulkarni AR, Ivy Carroll F, Lichtman AH, Papke RL, Thakur GA, Imad Damaj M. The interaction between alpha 7 nicotinic acetylcholine receptor and nuclear peroxisome proliferator-activated receptor-α represents a new antinociceptive signaling pathway in mice. Experimental Neurology. PMID 28606623 DOI: 10.1016/J.Expneurol.2017.06.014 |
0.362 |
|
| 2017 |
Papke RL, Stokes C, Damaj MI, Thakur GA, Manther K, Treinin M, Bagdas D, Kulkarni AR, Horenstein NA. Persistent activation of α7 nAChRs associated with stable induction of different desensitized states. British Journal of Pharmacology. PMID 28477386 DOI: 10.1111/Bph.13851 |
0.304 |
|
| 2017 |
Zhou H, Peng Y, Halikhedkar A, Fan P, Janero DR, Thakur GA, Mercier RW, Sun X, Ma X, Makriyannis A. Human Cannabinoid Receptor 2 Ligand-interaction Motif: Transmembrane Helix 2 Cysteine, C2.59(89), as Determinant of Classical Cannabinoid Agonist Activity and Binding Pose. Acs Chemical Neuroscience. PMID 28220706 DOI: 10.1021/Acschemneuro.7B00003 |
0.335 |
|
| 2017 |
Laprairie RB, Kulkarni PM, Deschamps JR, Kelly ME, Janero DR, Cascio MG, Stevenson LA, Pertwee RG, Kenakin T, Denovan-Wright EM, Thakur GA. Enantio-specific Allosteric Modulation of Cannabinoid 1 Receptor. Acs Chemical Neuroscience. PMID 28103441 DOI: 10.1021/Acschemneuro.6B00310 |
0.448 |
|
| 2017 |
Kyte SL, Toma W, Thakur G, Damaj MI, Gewirtz DA. Abstract 986: Targeting nicotinic acetylcholine receptors for the prevention and reversal of chemotherapy-induced peripheral neuropathy Cancer Research. 77: 986-986. DOI: 10.1158/1538-7445.Am2017-986 |
0.407 |
|
| 2016 |
Janero DR, Thakur GA. Leveraging allostery to improve G protein-coupled receptor (GPCR)-directed therapeutics: cannabinoid receptor 1 as a discovery target. Expert Opinion On Drug Discovery. PMID 27712124 DOI: 10.1080/17460441.2016.1245289 |
0.42 |
|
| 2016 |
Järbe TU, LeMay BJ, Thakur GA, Makriyannis A. A High Efficacy Cannabinergic Ligand (AM4054) used as a Discriminative Stimulus: Generalization to other Adamantyl Analogs and Δ(9)-THC in Rats. Pharmacology, Biochemistry, and Behavior. PMID 27264437 DOI: 10.1016/J.Pbb.2016.06.001 |
0.339 |
|
| 2016 |
Bagdas D, Wilkerson JL, Kulkarni A, Toma W, AlSharari S, Gul Z, Lichtman AH, Papke RL, Thakur GA, Imad Damaj M. The α7 nicotinic receptor dual allosteric agonist and positive allosteric modulator GAT107 reverses nociception in mouse models of inflammatory and neuropathic pain. British Journal of Pharmacology. PMID 27243753 DOI: 10.1111/Bph.13528 |
0.483 |
|
| 2016 |
Laprairie RB, Kulkarni AR, Kulkarni PM, Hurst DP, Lynch DL, Reggio PH, Janero DR, Pertwee RG, Stevenson LA, Kelly M, Denovan-Wright EM, Thakur GA. MAPPING CANNABINOID RECEPTOR 1 ALLOSTERIC SITE(S): CRITICAL MOLECULAR DETERMINANT AND SIGNALING PROFILE OF GAT100 - A NOVEL, POTENT AND IRREVERSIBLY BINDING PROBE. Acs Chemical Neuroscience. PMID 27046127 DOI: 10.1021/Acschemneuro.6B00041 |
0.461 |
|
| 2016 |
Horenstein NA, Papke RL, Kulkarni AR, Chaturbhuj GU, Stokes C, Manther K, Thakur GA. Critical molecular determinants of α7 nicotinic acetylcholine receptor allosteric activation: separation of direct allosteric activation and positive allosteric modulation. The Journal of Biological Chemistry. PMID 26742843 DOI: 10.1074/Jbc.M115.692392 |
0.368 |
|
| 2015 |
Kulkarni PM, Kulkarni AR, Korde A, Tichkule RB, Laprairie RB, Denovan-Wright EM, Zhou H, Janero DR, Zvonok N, Makriyannis A, Cascio MG, Pertwee RG, Thakur GA. Novel Electrophilic and Photoaffinity Covalent Probes for Mapping the Cannabinoid 1 Receptor Allosteric Site(s). Journal of Medicinal Chemistry. PMID 26529344 DOI: 10.1021/Acs.Jmedchem.5B01303 |
0.707 |
|
| 2015 |
Abalo R, Chen C, Vera G, Fichna J, Thakur GA, López-Pérez AE, Makriyannis A, Martín-Fontelles MI, Storr M. In vitro and non-invasive in vivo effects of the cannabinoid-1 receptor agonist AM841 on gastrointestinal motor function in the rat. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. PMID 26387676 DOI: 10.1111/Nmo.12668 |
0.346 |
|
| 2015 |
Keenan CM, Storr MA, Thakur GA, Wood JT, Wager-Miller J, Straiker A, Eno MR, Nikas SP, Bashashati M, Hu H, Mackie K, Makriyannis A, Sharkey KA. AM841, a covalent cannabinoid ligand, powerfully slows gastrointestinal motility in normal and stressed mice in a peripherally restricted manner. British Journal of Pharmacology. 172: 2406-18. PMID 25572435 DOI: 10.1111/Bph.13069 |
0.512 |
|
| 2015 |
Papke RL, Bagdas D, Kulkarni AR, Gould T, AlSharari SD, Thakur GA, Damaj MI. The analgesic-like properties of the alpha7 nAChR silent agonist NS6740 is associated with non-conducting conformations of the receptor. Neuropharmacology. 91: 34-42. PMID 25497451 DOI: 10.1016/J.Neuropharm.2014.12.002 |
0.41 |
|
| 2015 |
Nikas SP, Sharma R, Paronis CA, Kulkarni S, Thakur GA, Hurst D, Wood JT, Gifford RS, Rajarshi G, Liu Y, Raghav JG, Guo JJ, Järbe TU, Reggio PH, Bergman J, et al. Probing the carboxyester side chain in controlled deactivation (-)-δ(8)-tetrahydrocannabinols. Journal of Medicinal Chemistry. 58: 665-81. PMID 25470070 DOI: 10.1021/Jm501165D |
0.332 |
|
| 2014 |
Fichna J, Bawa M, Thakur GA, Tichkule R, Makriyannis A, McCafferty DM, Sharkey KA, Storr M. Cannabinoids alleviate experimentally induced intestinal inflammation by acting at central and peripheral receptors. Plos One. 9: e109115. PMID 25275313 DOI: 10.1371/Journal.Pone.0109115 |
0.725 |
|
| 2014 |
Gamage TF, Ignatowska-Jankowska BM, Wiley JL, Abdelrahman M, Trembleau L, Greig IR, Thakur GA, Tichkule R, Poklis J, Ross RA, Pertwee RG, Lichtman AH. In-vivo pharmacological evaluation of the CB1-receptor allosteric modulator Org-27569. Behavioural Pharmacology. 25: 182-5. PMID 24603340 DOI: 10.1097/Fbp.0000000000000027 |
0.733 |
|
| 2014 |
Papke RL, Horenstein NA, Kulkarni AR, Stokes C, Corrie LW, Maeng CY, Thakur GA. The activity of GAT107, an allosteric activator and positive modulator of α7 nicotinic acetylcholine receptors (nAChR), is regulated by aromatic amino acids that span the subunit interface. The Journal of Biological Chemistry. 289: 4515-31. PMID 24362025 DOI: 10.1074/Jbc.M113.524603 |
0.325 |
|
| 2013 |
Sharma R, Nikas SP, Paronis CA, Wood JT, Halikhedkar A, Guo JJ, Thakur GA, Kulkarni S, Benchama O, Raghav JG, Gifford RS, Järbe TU, Bergman J, Makriyannis A. Controlled-deactivation cannabinergic ligands. Journal of Medicinal Chemistry. 56: 10142-57. PMID 24286207 DOI: 10.1021/Jm4016075 |
0.475 |
|
| 2013 |
Chopda GR, Vemuri VK, Sharma R, Thakur GA, Makriyannis A, Paronis CA. Diuretic effects of cannabinoid agonists in mice. European Journal of Pharmacology. 721: 64-9. PMID 24099963 DOI: 10.1016/J.Ejphar.2013.09.053 |
0.431 |
|
| 2013 |
Thakur GA, Bajaj S, Paronis C, Peng Y, Bowman AL, Barak LS, Caron MG, Parrish D, Deschamps JR, Makriyannis A. Novel adamantyl cannabinoids as CB1 receptor probes. Journal of Medicinal Chemistry. 56: 3904-21. PMID 23621789 DOI: 10.1021/Jm4000775 |
0.422 |
|
| 2013 |
McLaughlin PJ, Thakur GA, Vemuri VK, McClure ED, Brown CM, Winston KM, Wood JT, Makriyannis A, Salamone JD. Behavioral effects of the novel potent cannabinoid CB1 agonist AM 4054. Pharmacology, Biochemistry, and Behavior. 109: 16-22. PMID 23603029 DOI: 10.1016/J.Pbb.2013.04.011 |
0.438 |
|
| 2013 |
Kangas BD, Delatte MS, Vemuri VK, Thakur GA, Nikas SP, Subramanian KV, Shukla VG, Makriyannis A, Bergman J. Cannabinoid discrimination and antagonism by CB(1) neutral and inverse agonist antagonists. The Journal of Pharmacology and Experimental Therapeutics. 344: 561-7. PMID 23287700 DOI: 10.1124/Jpet.112.201962 |
0.466 |
|
| 2013 |
Desai RI, Thakur GA, Vemuri VK, Bajaj S, Makriyannis A, Bergman J. Analysis of tolerance and behavioral/physical dependence during chronic CB1 agonist treatment: effects of CB1 agonists, antagonists, and noncannabinoid drugs. The Journal of Pharmacology and Experimental Therapeutics. 344: 319-28. PMID 23197773 DOI: 10.1124/Jpet.112.198374 |
0.301 |
|
| 2013 |
Paronis CA, Thakur GA, Bajaj S, Nikas SP, Vemuri VK, Makriyannis A, Bergman J. Diuretic effects of cannabinoids. The Journal of Pharmacology and Experimental Therapeutics. 344: 8-14. PMID 23019138 DOI: 10.1124/Jpet.112.199331 |
0.368 |
|
| 2012 |
Deng L, Guindon J, Vemuri VK, Thakur GA, White FA, Makriyannis A, Hohmann AG. The maintenance of cisplatin- and paclitaxel-induced mechanical and cold allodynia is suppressed by cannabinoid CBâ‚‚ receptor activation and independent of CXCR4 signaling in models of chemotherapy-induced peripheral neuropathy. Molecular Pain. 8: 71. PMID 22998838 DOI: 10.1186/1744-8069-8-71 |
0.447 |
|
| 2012 |
Dixon DD, Tius MA, Thakur GA, Zhou H, Bowman AL, Shukla VG, Peng Y, Makriyannis A. C3-heteroaroyl cannabinoids as photolabeling ligands for the CB2 cannabinoid receptor. Bioorganic & Medicinal Chemistry Letters. 22: 5322-5. PMID 22796181 DOI: 10.1016/J.Bmcl.2012.06.013 |
0.396 |
|
| 2011 |
Teng H, Thakur GA, Makriyannis A. Conformationally constrained analogs of BAY 59-3074 as novel cannabinoid receptor ligands. Bioorganic & Medicinal Chemistry Letters. 21: 5999-6002. PMID 21880487 DOI: 10.1016/J.Bmcl.2011.07.017 |
0.465 |
|
| 2011 |
Szymanski DW, Papanastasiou M, Melchior K, Zvonok N, Mercier RW, Janero DR, Thakur GA, Cha S, Wu B, Karger B, Makriyannis A. Mass spectrometry-based proteomics of human cannabinoid receptor 2: Covalent cysteine 6.47(257)-ligand interaction affording megagonist receptor activation Journal of Proteome Research. 10: 4789-4798. PMID 21861534 DOI: 10.1021/Pr2005583 |
0.341 |
|
| 2009 |
Thakur GA, Tichkule R, Bajaj S, Makriyannis A. Latest advances in cannabinoid receptor agonists. Expert Opinion On Therapeutic Patents. 19: 1647-73. PMID 19939187 DOI: 10.1517/13543770903436505 |
0.711 |
|
| 2008 |
Pei Y, Mercier RW, Anday JK, Thakur GA, Zvonok AM, Hurst D, Reggio PH, Janero DR, Makriyannis A. Ligand-binding architecture of human CB2 cannabinoid receptor: evidence for receptor subtype-specific binding motif and modeling GPCR activation. Chemistry & Biology. 15: 1207-19. PMID 19022181 DOI: 10.1016/J.Chembiol.2008.10.011 |
0.481 |
|
| 2008 |
Rahn EJ, Zvonok AM, Thakur GA, Khanolkar AD, Makriyannis A, Hohmann AG. Selective activation of cannabinoid CB2 receptors suppresses neuropathic nociception induced by treatment with the chemotherapeutic agent paclitaxel in rats. The Journal of Pharmacology and Experimental Therapeutics. 327: 584-91. PMID 18664590 DOI: 10.1124/Jpet.108.141994 |
0.39 |
|
| 2008 |
Kapur A, Samaniego P, Thakur GA, Makriyannis A, Abood ME. Mapping the structural requirements in the CB1 cannabinoid receptor transmembrane helix II for signal transduction. The Journal of Pharmacology and Experimental Therapeutics. 325: 341-8. PMID 18174385 DOI: 10.1124/Jpet.107.133256 |
0.333 |
|
| 2008 |
Bergman J, Delatte MS, Paronis CA, Vemuri K, Thakur GA, Makriyannis A. Some effects of CB1 antagonists with inverse agonist and neutral biochemical properties. Physiology & Behavior. 93: 666-70. PMID 18076956 DOI: 10.1016/J.Physbeh.2007.11.007 |
0.351 |
|
| 2007 |
Khanolkar AD, Lu D, Ibrahim M, Duclos RI, Thakur GA, Malan TP, Porreca F, Veerappan V, Tian X, George C, Parrish DA, Papahatjis DP, Makriyannis A. Cannabilactones: a novel class of CB2 selective agonists with peripheral analgesic activity. Journal of Medicinal Chemistry. 50: 6493-500. PMID 18038967 DOI: 10.1021/Jm070441U |
0.422 |
|
| 2007 |
Kapur A, Hurst DP, Fleischer D, Whitnell R, Thakur GA, Makriyannis A, Reggio PH, Abood ME. Mutation studies of Ser7.39 and Ser2.60 in the human CB1 cannabinoid receptor: evidence for a serine-induced bend in CB1 transmembrane helix 7. Molecular Pharmacology. 71: 1512-24. PMID 17384224 DOI: 10.1124/Mol.107.034645 |
0.38 |
|
| 2006 |
Pavlopoulos S, Thakur GA, Nikas SP, Makriyannis A. Cannabinoid receptors as therapeutic targets. Current Pharmaceutical Design. 12: 1751-69. PMID 16712486 DOI: 10.2174/138161206776873743 |
0.474 |
|
| 2006 |
Thakur GA, Nikas SP, Duclos RI, Makriyannis A. Methods for the synthesis of cannabinergic ligands Methods in Molecular Medicine. 123: 113-148. PMID 16506405 DOI: 10.1385/1-59259-999-0:113 |
0.432 |
|
| 2005 |
Thakur GA, Nikas SP, Li C, Makriyannis A. Structural requirements for cannabinoid receptor probes Handbook of Experimental Pharmacology. 168: 209-246. PMID 16596776 DOI: 10.1007/3-540-26573-2_7 |
0.46 |
|
| 2005 |
Picone RP, Khanolkar AD, Xu W, Ayotte LA, Thakur GA, Hurst DP, Abood ME, Reggio PH, Fournier DJ, Makriyannis A. (-)-7'-Isothiocyanato-11-hydroxy-1',1'-dimethylheptylhexahydrocannabinol (AM841), a high-affinity electrophilic ligand, interacts covalently with a cysteine in helix six and activates the CB1 cannabinoid receptor. Molecular Pharmacology. 68: 1623-35. PMID 16157695 DOI: 10.1124/Mol.105.014407 |
0.368 |
|
| 2005 |
Thakur GA, Nikas SP, Makriyannis A. CB1 cannabinoid receptor ligands Mini-Reviews in Medicinal Chemistry. 5: 631-640. PMID 16026309 DOI: 10.2174/1389557054368772 |
0.472 |
|
| 2005 |
Lu D, Meng Z, Thakur GA, Fan P, Steed J, Tartal CL, Hurst DP, Reggio PH, Deschamps JR, Parrish DA, George C, Järbe TU, Lamb RJ, Makriyannis A. Adamantyl cannabinoids: a novel class of cannabinergic ligands. Journal of Medicinal Chemistry. 48: 4576-85. PMID 15999995 DOI: 10.1021/Jm058175C |
0.377 |
|
| 2002 |
Thakur GA, Palmer SL, Harrington PE, Stergiades IA, Tius MA, Makriyannis A. Enantiomeric resolution of a novel chiral cannabinoid receptor ligand. Journal of Biochemical and Biophysical Methods. 54: 415-22. PMID 12543516 DOI: 10.1016/S0165-022X(02)00144-6 |
0.451 |
|
| 2002 |
Palmer SL, Thakur GA, Makriyannis A. Cannabinergic ligands. Chemistry and Physics of Lipids. 121: 3-19. PMID 12505686 DOI: 10.1016/S0009-3084(02)00143-3 |
0.483 |
|
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