| Year |
Citation |
Score |
| 2018 |
Foley C, Shaw A, Hulme C. Aza-Riley Oxidation of Ugi-Azide and Ugi-3CR Products toward Vicinal Tricarbonyl Amides: Two-Step MCR-Oxidation Methodology Accessing Functionalized α,β-Diketoamides and α,β-Diketotetrazoles. Organic Letters. PMID 29466017 DOI: 10.1021/Acs.Orglett.7B03977 |
0.333 |
|
| 2017 |
Martinez-Ariza G, Mehari BT, Pinho LAG, Foley C, Day K, Jewett JC, Hulme C. Synthesis of fluorescent heterocycles via a Knoevenagel/[4 + 1]-cycloaddition cascade using acetyl cyanide. Organic & Biomolecular Chemistry. PMID 28685790 DOI: 10.1039/C7Ob01239J |
0.383 |
|
| 2017 |
Collet JW, Foley C, Shaw AY, Orru RVA, Ruijter E, Hulme C. Copper(i) catalyzed oxidative hydrolysis of Ugi 3-component and Ugi-azide reaction products towards 2° α-ketoamides and α-ketotetrazoles. Organic & Biomolecular Chemistry. PMID 28682397 DOI: 10.1039/C7Ob00881C |
0.36 |
|
| 2017 |
Foley C, Shaw A, Hulme C. Oxidative Deaminations and Deisatinylations of Ugi-Azide and Ugi-3CR Products: A Two-Step MCR-Oxidation Protocol toward Functionalized α-Ketoamides and α-Ketotetrazoles. Organic Letters. PMID 28409929 DOI: 10.1021/Acs.Orglett.7B00710 |
0.403 |
|
| 2016 |
Foley C, Shaw A, Hulme C. Two-Step Route to Diverse N-Functionalized Peptidomimetic-like Isatins through an Oxidation/Intramolecular Oxidative-Amidation Cascade of Ugi Azide and Ugi Three-Component Reaction Products. Organic Letters. PMID 27631344 DOI: 10.1021/Acs.Orglett.6B02383 |
0.361 |
|
| 2016 |
Martinez-Ariza G, McConnell N, Hulme C. One-Pot Two-Step Multicomponent Process of Indole and Other Nitrogenous Heterocycles or Amines toward α-Oxo-acetamidines. Organic Letters. 18: 1864-7. PMID 27020621 DOI: 10.1021/Acs.Orglett.6B00634 |
0.421 |
|
| 2015 |
Xu Z, Martinez-Ariza G, Cappelli AP, Roberts SA, Hulme C. (Z)-Stereoselective Synthesis of Mono- and Bis-heterocyclic Benzimidazol-2-ones via Cascade Processes Coupled with the Ugi Multicomponent Reaction. The Journal of Organic Chemistry. PMID 26309135 DOI: 10.1021/Acs.Joc.5B00955 |
0.435 |
|
| 2015 |
Martinez-Ariza G, Ayaz M, Roberts SA, Rabanal-León WA, Arratia-Pérez R, Hulme C. The Synthesis of Stable, Complex Organocesium Tetramic Acids through the Ugi Reaction and Cesium-Carbonate-Promoted Cascades. Angewandte Chemie (International Ed. in English). PMID 26270696 DOI: 10.1002/Anie.201504377 |
0.394 |
|
| 2015 |
Snieckus V, Miranzadeh M, Medda F, Martinez-Ariza G, Hulme C. Imidazotetrazolodiazepinones by a Ugi–Azide Multicomponent Reaction Synfacts. 11: 1255-1255. DOI: 10.1055/S-0035-1560900 |
0.34 |
|
| 2015 |
Medda F, Martinez-Ariza G, Hulme C. A facile and concise route toward the synthesis of novel imidazo-tetrazolodiazepinones via post-condensation modifications of the Ugi-azide adduct Tetrahedron Letters. 56: 5295-5298. DOI: 10.1016/J.Tetlet.2015.07.083 |
0.438 |
|
| 2015 |
Martinez-Ariza G, Nunez-Rios J, Lee YS, Hulme C. Acetyl cyanide as a cyanide source in a tandem catalyst-free modified Groebke-Blackburn-Bienaymé [4+1]-cycloaddition-Strecker cascade Tetrahedron Letters. 56: 1038-1040. DOI: 10.1016/J.Tetlet.2014.12.127 |
0.398 |
|
| 2014 |
Medda F, Hulme C. Exploiting the Divalent Nature of Isonitriles: a novel Pictet-Spengler Amidination process. Tetrahedron Letters. 55: 3328-3331. PMID 24954960 DOI: 10.1016/J.Tetlet.2014.04.043 |
0.404 |
|
| 2014 |
Ayaz M, Xu Z, Hulme C. Novel succinct routes to Quinoxalines and 2-Benzimidazolylquinoxalines via the Ugi reaction. Tetrahedron Letters. 55: 3406-3409. PMID 24932052 DOI: 10.1016/J.Tetlet.2014.04.013 |
0.449 |
|
| 2014 |
Martinez-Ariza G, Ayaz M, Medda F, Hulme C. Synthesis of diverse nitrogen-enriched heterocyclic scaffolds using a suite of tunable one-pot multicomponent reactions. The Journal of Organic Chemistry. 79: 5153-62. PMID 24788091 DOI: 10.1021/Jo500723D |
0.444 |
|
| 2014 |
Bell CE, Shaw AY, De Moliner F, Hulme C. MCRs reshaped into a switchable microwave-assisted protocol toward 5-aminoimidazoles and dihydrotriazines. Tetrahedron. 7: 54-59. PMID 24535889 DOI: 10.1016/J.Tet.2013.11.035 |
0.608 |
|
| 2014 |
Xu Z, De Moliner F, Cappelli AP, Ayaz M, Hulme C. Expeditious routes to polycyclic molecular frameworks via one-pot, two-step Ugi ring-closing sequences Synlett. 25: 225-228. DOI: 10.1055/S-0033-1340219 |
0.434 |
|
| 2014 |
Ayaz M, Martinez-Ariza G, Hulme C. A robust protocol for the synthesis of quinoxalines and 5 H -benzo[ e ][1,4]diazepines via the acidless Ugi reaction Synlett. 25: 1680-1684. DOI: 10.1055/S-0033-1339135 |
0.418 |
|
| 2013 |
Martinez-Ariza G, Ayaz M, Hulme C. A simple one-pot 2-step N-1-alkylation of indoles with α-iminoketones toward the expeditious 3-step synthesis of N-1-quinoxaline-indoles. Tetrahedron Letters. 54. PMID 24327792 DOI: 10.1016/J.Tetlet.2013.09.113 |
0.392 |
|
| 2013 |
Gunawan S, Hulme C. Construction of functionalized tricyclic dihydropyrazino-quinazolinedione chemotypes via an Ugi/N-acyliminium ion cyclization cascade. Tetrahedron Letters. 54: 4467-4470. PMID 23997316 DOI: 10.1016/J.Tetlet.2013.06.042 |
0.377 |
|
| 2013 |
Gunawan S, Hulme C. Bifunctional building blocks in the Ugi-azide condensation reaction: a general strategy toward exploration of new molecular diversity. Organic & Biomolecular Chemistry. 11: 6036-46. PMID 23912086 DOI: 10.1039/C3Ob40900G |
0.442 |
|
| 2013 |
Xu Z, De Moliner F, Cappelli AP, Hulme C. Aldol reactions in multicomponent reaction based domino pathways: a multipurpose enabling tool in heterocyclic chemistry. Organic Letters. 15: 2738-41. PMID 23718233 DOI: 10.1021/Ol401068U |
0.401 |
|
| 2013 |
Medda F, Sells E, Chang HH, Dietrich J, Chappeta S, Smith B, Gokhale V, Meuillet EJ, Hulme C. Synthesis and biological activity of aminophthalazines and aminopyridazines as novel inhibitors of PGE2 production in cells. Bioorganic & Medicinal Chemistry Letters. 23: 528-31. PMID 23237838 DOI: 10.1016/J.Bmcl.2012.11.030 |
0.304 |
|
| 2013 |
Hsu MY, Dietrich J, Hulme C, Shaw AY. Synthesis of Di- and Tri-Substituted Imidazole-4-carboxylates via PBu3-Mediated [3 + 2] Cycloaddition Synthetic Communications. 43: 1538-1542. DOI: 10.1080/00397911.2011.644846 |
0.402 |
|
| 2013 |
Martinez-Ariza G, Dietrich J, Moliner FD, Hulme C. A tandem [3+2] cycloaddition-elimination cascade reaction to generate pyrrolo-[3,4-c]pyrrole-1,3-diones Synlett. 24: 1801-1804. DOI: 10.1055/S-0033-1338872 |
0.431 |
|
| 2013 |
Shaw AY, Denning CR, Hulme C. One-pot two-step synthesis of quinoxalinones and diazepinones via a tandem oxidative amidation-deprotection-cyclization sequence Synthesis (Germany). 45: 459-462. DOI: 10.1055/S-0032-1317983 |
0.383 |
|
| 2012 |
Shaw AY, Xu Z, Hulme C. Ugi/Robinson-Gabriel reactions directed toward the synthesis of 2,4,5-trisubstituted oxazoles. Tetrahedron Letters. 53: 1998-2000. PMID 23559684 DOI: 10.1016/J.Tetlet.2012.02.030 |
0.446 |
|
| 2012 |
De Moliner F, Hulme C. A Van Leusen deprotection-cyclization strategy as a fast entry into two imidazoquinoxaline families. Tetrahedron Letters. 53: 5787-5790. PMID 23504533 DOI: 10.1016/J.Tetlet.2012.08.072 |
0.401 |
|
| 2012 |
Shaw AY, Denning CR, Hulme C. Selenium dioxide-mediated synthesis of α-ketoamides from arylglyoxals and secondary amines. Tetrahedron Letters. 53: 4151-4153. PMID 23180891 DOI: 10.1016/J.Tetlet.2012.05.136 |
0.418 |
|
| 2012 |
Gunawan S, Ayaz M, De Moliner F, Frett B, Kaiser C, Patrick N, Xu Z, Hulme C. Synthesis of Tetrazolo-Fused Benzodiazepines and Benzodiazepinones by a Two-Step Protocol Using an Ugi-Azide Reaction for Initial Diversity Generation. Tetrahedron. 68: 5606-5611. PMID 22923851 DOI: 10.1016/J.Tet.2012.04.068 |
0.454 |
|
| 2012 |
Xu Z, De Moliner F, Cappelli AP, Hulme C. Ugi/aldol sequence: expeditious entry to several families of densely substituted nitrogen heterocycles. Angewandte Chemie (International Ed. in English). 51: 8037-40. PMID 22753341 DOI: 10.1002/Anie.201202575 |
0.367 |
|
| 2012 |
Xu Z, Ayaz M, Cappelli AA, Hulme C. General one-pot, two-step protocol accessing a range of novel polycyclic heterocycles with high skeletal diversity. Acs Combinatorial Science. 14: 460-4. PMID 22746181 DOI: 10.1021/Co300046R |
0.439 |
|
| 2012 |
Gunawan S, Nichol G, Hulme C. Concise route to a series of novel 3-(tetrazol-5-yl)quinoxalin-2(1H)-ones. Tetrahedron Letters. 53: 1664-1667. PMID 22707799 DOI: 10.1016/J.Tetlet.2012.01.080 |
0.417 |
|
| 2012 |
Xu Z, Shaw AY, Nichol GS, Cappelli AP, Hulme C. Applications of ortho-phenylisonitrile and ortho-N-Boc aniline for the two-step preparation of novel bis-heterocyclic chemotypes. Molecular Diversity. 16: 607-12. PMID 22622389 DOI: 10.1007/S11030-012-9374-1 |
0.448 |
|
| 2012 |
Gunawan S, Keck K, Laetsch A, Hulme C. Synthesis of peptidomimetics, δ- and ε-lactam tetrazoles. Molecular Diversity. 16: 601-6. PMID 22622388 DOI: 10.1007/S11030-012-9373-2 |
0.463 |
|
| 2012 |
Shaw AY, McLaren JA, Nichol GS, Hulme C. Hydrazine-mediated cyclization of Ugi products to synthesize novel 3-hydroxypyrazoles. Tetrahedron Letters. 53: 2592-2594. PMID 22544981 DOI: 10.1016/J.Tetlet.2012.03.033 |
0.411 |
|
| 2012 |
Shaw AY, Medda F, Hulme C. Facile and rapid route for the synthesis of novel conformationally constrained norstatine analogs via PADAM-cyclization methodology. Tetrahedron Letters. 53: 1313-1315. PMID 22368307 DOI: 10.1016/J.Tetlet.2011.12.073 |
0.479 |
|
| 2012 |
De Moliner F, Hulme C. Straightforward assembly of phenylimidazoquinoxalines via a one-pot two-step MCR process. Organic Letters. 14: 1354-7. PMID 22356134 DOI: 10.1021/Ol3003282 |
0.372 |
|
| 2012 |
Gunawan S, Petit J, Hulme C. Concise one-pot preparation of unique bis-pyrrolidinone tetrazoles. Acs Combinatorial Science. 14: 160-3. PMID 22330239 DOI: 10.1021/Co200209A |
0.432 |
|
| 2012 |
Xu Z, Shaw AY, Dietrich J, Cappelli AP, Nichol G, Hulme C. Facile, novel two-step syntheses of benzimidazoles, bis-benzimidazoles, and bis-benzimidazole-dihydroquinoxalines. Molecular Diversity. 16: 73-9. PMID 22237832 DOI: 10.1007/S11030-011-9354-X |
0.423 |
|
| 2012 |
Sells E, Medda F, Chang H, Gokhale V, Hulme C, Meuillet EJ. Abstract 2834: Discovery of a novel class of prostaglandin e2 synthesis inhibitors with anti-tumor activity in colorectal cancer Cancer Research. 72: 2834-2834. DOI: 10.1158/1538-7445.Am2012-2834 |
0.305 |
|
| 2012 |
Medda F, Hulme C. A facile and rapid route for the synthesis of novel 1,5-substituted tetrazole hydantoins and thiohydantoins via a TMSN 3-Ugi/RNCX cyclization Tetrahedron Letters. 53: 5593-5596. DOI: 10.1016/J.Tetlet.2012.07.135 |
0.448 |
|
| 2011 |
Ayaz M, Dietrich J, Hulme C. A novel route to synthesize libraries of quinoxalines via Petasis methodology in two synthetic operations. Tetrahedron Letters. 52: 4821-4823. PMID 21987596 DOI: 10.1016/J.Tetlet.2011.06.115 |
0.427 |
|
| 2010 |
Gunawan S, Nichol GS, Chappeta S, Dietrich J, Hulme C. Concise Preparation of Novel Tricyclic Chemotypes: Fused Hydantoin-benzodiazepines. Tetrahedron Letters. 51: 4689-4692. PMID 20802841 DOI: 10.1016/J.Tetlet.2010.06.131 |
0.448 |
|
| 2010 |
Xu Z, Dietrich J, Shaw AY, Hulme C. Two step syntheses of fused quinoxaline-benzodiazepines and bis-benzodiazepines. Tetrahedron Letters. 51: 4566-4569. PMID 20706616 DOI: 10.1016/J.Tetlet.2010.06.116 |
0.401 |
|
| 2010 |
Dietrich J, Kaiser C, Meurice N, Hulme C. Concise Two-Step Solution Phase Syntheses of four novel Dihydroquinazoline scaffolds. Tetrahedron Letters. 51: 3951-3955. PMID 20625451 DOI: 10.1016/J.Tetlet.2010.05.108 |
0.411 |
|
| 2009 |
Hulme C, Dietrich J. Emerging molecular diversity from the intra-molecular Ugi reaction: iterative efficiency in medicinal chemistry. Molecular Diversity. 13: 195-207. PMID 19205916 DOI: 10.1007/S11030-009-9111-6 |
0.388 |
|
| 2009 |
Hulme C, Chappeta S, Dietrich J. A simple, cheap alternative to 'designer convertible isonitriles' expedited with microwaves Tetrahedron Letters. 50: 4054-4057. DOI: 10.1016/J.Tetlet.2009.04.095 |
0.371 |
|
| 2009 |
Hulme C, Chappeta S, Griffith C, Lee YS, Dietrich J. An efficient solution phase synthesis of triazadibenzoazulenones : 'designer isonitrile free' methodology enabled by microwaves Tetrahedron Letters. 50: 1939-1942. DOI: 10.1016/J.Tetlet.2009.02.099 |
0.429 |
|
| 2008 |
Hulme C, Lee YS. Emerging approaches for the syntheses of bicyclic imidazo[1,2-x]-heterocycles. Molecular Diversity. 12: 1-15. PMID 18409015 DOI: 10.1007/S11030-008-9072-1 |
0.358 |
|
| 2007 |
Umkehrer M, Ross G, Jäger N, Burdack C, Kolb J, Hu H, Alvim-Gaston M, Hulme C. Expeditious synthesis of imidazo[1,2-c]pyrimidines via a [4+1]-cycloaddition Tetrahedron Letters. 48: 2213-2216. DOI: 10.1016/J.Tetlet.2007.01.061 |
0.398 |
|
| 2006 |
Masquelin T, Bui H, Brickley B, Stephenson G, Schwerkoske J, Hulme C. Sequential Ugi/Strecker reactions via microwave assisted organic synthesis: novel 3-center-4-component and 3-center-5-component multi-component reactions Tetrahedron Letters. 47: 2989-2991. DOI: 10.1016/J.Tetlet.2006.01.160 |
0.412 |
|
| 2006 |
Salamant W, Hulme C. Unique one step, multicomponent α,β,β-oxidations of carbamates with Willgerodt-like hypervalent iodine reagents - An example of triple C-H bond activation Tetrahedron Letters. 47: 605-609. DOI: 10.1016/J.Tetlet.2005.10.169 |
0.324 |
|
| 2005 |
Schwerkoske J, Masquelin T, Perun T, Hulme C. New multi-component reaction accessing 3-aminoimidazo[1,2-a]pyridines Tetrahedron Letters. 46: 8355-8357. DOI: 10.1016/J.Tetlet.2005.09.181 |
0.448 |
|
| 2003 |
Vasquez TE, Nixey T, Chenera B, Gore V, Bartberger MD, Sun Y, Hulme C. One-pot microwave assisted preparation of pyrazoloquinazolinone libraries. Molecular Diversity. 7: 161-4. PMID 14870845 DOI: 10.1023/B:Modi.0000006917.06401.48 |
0.394 |
|
| 2003 |
Hulme C, Bienaymé H, Nixey T, Chenera B, Jones W, Tempest P, Smith AL. Library generation via postcondensation modifications of isocyanide-based multicomponent reactions. Methods in Enzymology. 369: 469-96. PMID 14722968 DOI: 10.1016/S0076-6879(03)69024-5 |
0.395 |
|
| 2003 |
Hulme C, Gore V. "Multi-component reactions : emerging chemistry in drug discovery" 'from xylocain to crixivan'. Current Medicinal Chemistry. 10: 51-80. PMID 12570721 DOI: 10.2174/0929867033368600 |
0.402 |
|
| 2003 |
Tempest P, Pettus L, Gore V, Hulme C. MCC/SNAr methodology. Part 2: Novel three-step solution phase access to libraries of benzodiazepines Tetrahedron Letters. 44: 1947-1950. DOI: 10.1016/S0040-4039(03)00084-4 |
0.398 |
|
| 2002 |
Nixey T, Hulme C. Rapid generation of cis-constrained norstatine analogs using a TMSN3-modified Passerini MCC/N-capping strategy Tetrahedron Letters. 43: 6833-6835. DOI: 10.1016/S0040-4039(02)01505-8 |
0.401 |
|
| 2002 |
Nixey T, Kelly M, Semin D, Hulme C. Short solution phase preparation of fused azepine-tetrazoles via a UDC (Ugi/de-Boc/cyclize) strategy Tetrahedron Letters. 43: 3681-3684. DOI: 10.1016/S0040-4039(02)00636-6 |
0.448 |
|
| 2002 |
Nixey T, Tempest P, Hulme C. Two-step solution-phase synthesis of novel quinoxalinones utilizing a UDC (Ugi/de-Boc/cyclize) strategy Tetrahedron Letters. 43: 1637-1639. DOI: 10.1016/S0040-4039(02)00101-6 |
0.398 |
|
| 2001 |
Tempest P, Ma V, Kelly MG, Jones W, Hulme C. MCC/SNAr methodology. Part 1: Novel access to a range of heterocyclic cores Tetrahedron Letters. 42: 4963-4968. DOI: 10.1016/S0040-4039(01)00920-0 |
0.437 |
|
| 2001 |
Tempest P, Ma V, Thomas S, Hua Z, Kelly MG, Hulme C. Two-step solution-phase synthesis of novel benzimidazoles utilizing a UDC (Ugi/de-Boc/cyclize) strategy Tetrahedron Letters. 42: 4959-4962. DOI: 10.1016/S0040-4039(01)00919-4 |
0.399 |
|
| 2000 |
Bienaymé H, Hulme C, Oddon G, Schmitt P. Maximizing Synthetic Efficiency: Multi-Component Transformations Lead the Way Chemistry: a European Journal. 6: 3321-3329. PMID 11039522 DOI: 10.1002/1521-3765(20000915)6:18<3321::Aid-Chem3321>3.0.Co;2-A |
0.308 |
|
| 2000 |
Hulme C, Ma L, Kumar NV, Krolikowski PH, Allen AC, Labaudiniere R. Novel applications of resin bound α-amino acids for the synthesis of benzodiazepines (via Wang resin) and ketopiperazines (via hydroxymethyl resin) Tetrahedron Letters. 41: 1509-1514. DOI: 10.1016/S0040-4039(99)02326-6 |
0.384 |
|
| 2000 |
Nixey T, Kelly M, Hulme C. The one-pot solution phase preparation of fused tetrazole-ketopiperazines Tetrahedron Letters. 41: 8729-8733. DOI: 10.1016/S0040-4039(00)01563-X |
0.426 |
|
| 2000 |
Hulme C, Ma L, Romano JJ, Morton G, Tang SY, Cherrier MP, Choi S, Salvino J, Labaudiniere R. Novel applications of carbon dioxide/MeOH for the synthesis of hydantoins and cyclic ureas via the Ugi reaction Tetrahedron Letters. 41: 1889-1893. DOI: 10.1016/S0040-4039(00)00053-8 |
0.443 |
|
| 2000 |
Hulme C, Ma L, Cherrier M, Romano JJ, Morton G, Duquenne C, Salvino J, Labaudiniere R. Novel applications of convertible isonitriles for the synthesis of mono and bicyclic γ-lactams via a UDC strategy Tetrahedron Letters. 41: 1883-1887. DOI: 10.1016/S0040-4039(00)00052-6 |
0.454 |
|
| 1999 |
McGarry DG, Regan JR, Volz FA, Hulme C, Moriarty KJ, Djuric SW, Souness JE, Miller BE, Travis JJ, Sweeney DM. Benzofuran based PDE4 inhibitors. Bioorganic & Medicinal Chemistry. 7: 1131-9. PMID 10428384 DOI: 10.1016/S0968-0896(99)00038-3 |
0.339 |
|
| 1999 |
Hulme C, Ma L, Romano J, Morrissette M. Remarkable three-step-one-pot solution phase preparation of novel imidazolines utilizing a UDC (Ugi/de-Boc/cyclize) strategy Tetrahedron Letters. 40: 7925-7928. DOI: 10.1016/S0040-4039(99)01580-4 |
0.397 |
|
| 1999 |
Hulme C, Cherrier MP. Novel applications of ethyl glyoxalate with the Ugi MCR Tetrahedron Letters. 40: 5295-5299. DOI: 10.1016/S0040-4039(99)00960-0 |
0.447 |
|
| 1998 |
Hulme C, Mathew R, Moriarty K, Miller B, Ramanjulu M, Cox P, Souness J, Page KM, Uhl J, Travis J, Labaudiniere R, Huang F, Djuric SW. Orally active indole N-oxide PDE4 inhibitors. Bioorganic & Medicinal Chemistry Letters. 8: 3053-8. PMID 9873675 DOI: 10.1016/S0960-894X(98)00572-1 |
0.317 |
|
| 1998 |
Hulme C, Moriarty K, Miller B, Mathew R, Ramanjulu M, Cox P, Souness J, Page KM, Uhl J, Travis J, Huang FC, Labaudiniere R, Djuric SW. The synthesis and biological evaluation of a novel series of indole PDE4 inhibitors I. Bioorganic & Medicinal Chemistry Letters. 8: 1867-72. PMID 9873449 DOI: 10.1016/S0960-894X(98)00324-2 |
0.347 |
|
| 1998 |
Hulme C, Moriarty K, Huang FC, Mason J, McGarry D, Labaudiniere R, Souness J, Djuric S. Quaternary substituted PDE IV inhibitors II: the synthesis and in vitro evaluation of a novel series of gamma-lactams. Bioorganic & Medicinal Chemistry Letters. 8: 399-404. PMID 9871693 DOI: 10.1016/S0960-894X(98)00036-5 |
0.345 |
|
| 1998 |
Hulme C, Poli GB, Huang FC, Souness JE, Djuric SW. Quaternary substituted PDE4 inhibitors I: the synthesis and in vitro evaluation of a novel series of oxindoles. Bioorganic & Medicinal Chemistry Letters. 8: 175-8. PMID 9871649 DOI: 10.1016/S0960-894X(97)10206-2 |
0.349 |
|
| 1998 |
Hulme C, Peng J, Tang SY, Burns CJ, Morize I, Labaudiniere R. Improved Procedure for the Solution Phase Preparation of 1,4-Benzodiazepine-2,5-dione Libraries via Armstrong's Convertible Isonitrile and the Ugi Reaction Journal of Organic Chemistry. 63: 8021-8023. DOI: 10.1021/Jo980622R |
0.347 |
|
| 1998 |
Hulme C, Peng J, Louridas B, Menard P, Krolikowski P, Kumar NV. Applications of N-BOC-diamines for the solution phase synthesis of ketopiperazine libraries utilizing a Ugi/De-BOC/Cyclization (UDC) strategy Tetrahedron Letters. 39: 8047-8050. DOI: 10.1016/S0040-4039(98)01770-5 |
0.426 |
|
| 1998 |
Hulme C, Peng J, Morton G, Salvino JM, Herpin T, Labaudiniere R. Novel safety-catch linker and its application with a Ugi/De-BOC/Cyclization (UDC) strategy to access carboxylic acids, 1,4-benzodiazepines, diketopiperazines, ketopiperazines and dihydroquinoxalinones Tetrahedron Letters. 39: 7227-7230. DOI: 10.1016/S0040-4039(98)01593-7 |
0.394 |
|
| 1998 |
Hulme C, Morrissette MM, Volz FA, Burns CJ. The solution phase synthesis of diketopiperazine libraries via the Ugi reaction: Novel application of Armstrong's convertible isonitrile Tetrahedron Letters. 39: 1113-1116. DOI: 10.1016/S0040-4039(97)10795-X |
0.428 |
|
| 1996 |
Magnus P, Lacour J, Evans PA, Roe MB, Hulme C. Hypervalent Iodine Chemistry: New Oxidation Reactions Using the Iodosylbenzene−Trimethylsilyl Azide Reagent Combination. Direct α- and β-Azido Functionalization of Triisopropylsilyl Enol Ethers Journal of the American Chemical Society. 118: 3406-3418. DOI: 10.1021/Ja953906R |
0.357 |
|
| 1996 |
Claridge TD, Hulme C, Kelly RJ, Lee V, Nash IA, Schofield CJ. Synthesis and analysis of Leu-enkephalin analogues containing reverse turn peptidomimetics Bioorganic & Medicinal Chemistry Letters. 6: 485-490. DOI: 10.1016/0960-894X(96)00055-8 |
0.488 |
|
| 1995 |
Magnus P, Roe MB, Hulme C. New trialkylsilyl enol ether chemistry: Direct 1,2-bis-azidonation of triisopropylsilyl enol ethers: An azido-radical addition process promoted by TEMPO Journal of the Chemical Society, Chemical Communications. 263-265. DOI: 10.1039/C39950000263 |
0.311 |
|
| 1994 |
Baldwin JE, Claridge TD, Hulme C, Rodger A, Schofield CJ. Comments on the use of a dichromophoric circular dichroism assay for the identification of beta-turns in peptides. International Journal of Peptide and Protein Research. 43: 180-3. PMID 8200737 DOI: 10.1111/J.1399-3011.1994.Tb00520.X |
0.477 |
|
| 1994 |
Magnus P, Hulme C. Oxidation of L-Proline methyl ester derivatives with the iodosylbenzene/trimethylsilylazide reagent combination Tetrahedron Letters. 35: 8097-8100. DOI: 10.1016/0040-4039(94)88252-5 |
0.306 |
|
| 1993 |
Baldwin JE, Hulme C, Schofield CJ, Edwards AJ. Synthesis of potential β-turn bicyclic dipeptide mimetics Journal of the Chemical Society, Chemical Communications. 935-936. DOI: 10.1039/C39930000935 |
0.532 |
|
| 1993 |
Baldwin JE, Hulme C, Edwards AJ, Schofield CJ, Parkes KE. Synthesis of a bicyclic γ-lactam dipeptide analogue Tetrahedron Letters. 34: 1665-1668. DOI: 10.1016/0040-4039(93)85036-V |
0.615 |
|
| Show low-probability matches. |