| Year |
Citation |
Score |
| 2022 |
Girdhar K, Hoffman GE, Bendl J, Rahman S, Dong P, Liao W, Hauberg ME, Sloofman L, Brown L, Devillers O, Kassim BS, Wiseman JR, Park R, Zharovsky E, Jacobov R, ... ... Haroutunian V, et al. Chromatin domain alterations linked to 3D genome organization in a large cohort of schizophrenia and bipolar disorder brains. Nature Neuroscience. PMID 35332326 DOI: 10.1038/s41593-022-01032-6 |
0.606 |
|
| 2020 |
Beckmann ND, Lin WJ, Wang M, Cohain AT, Charney AW, Wang P, Ma W, Wang YC, Jiang C, Audrain M, Comella PH, Fakira AK, Hariharan SP, Belbin GM, Girdhar K, ... ... Haroutunian V, et al. Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease. Nature Communications. 11: 3942. PMID 32770063 DOI: 10.1038/S41467-020-17405-Z |
0.341 |
|
| 2020 |
Wang H, Dey KK, Chen PC, Li Y, Niu M, Cho JH, Wang X, Bai B, Jiao Y, Chepyala SR, Haroutunian V, Zhang B, Beach TG, Peng J. Integrated analysis of ultra-deep proteomes in cortex, cerebrospinal fluid and serum reveals a mitochondrial signature in Alzheimer's disease. Molecular Neurodegeneration. 15: 43. PMID 32711556 DOI: 10.1186/S13024-020-00384-6 |
0.31 |
|
| 2020 |
Cao J, Huang M, Guo L, Zhu L, Hou J, Zhang L, Pero A, Ng S, El Gaamouch F, Elder G, Sano M, Goate A, Tcw J, Haroutunian V, Zhang B, et al. MicroRNA-195 rescues ApoE4-induced cognitive deficits and lysosomal defects in Alzheimer's disease pathogenesis. Molecular Psychiatry. PMID 32632205 DOI: 10.1038/S41380-020-0824-3 |
0.308 |
|
| 2020 |
Frajman A, Maggio N, Muler I, Haroutunian V, Katsel P, Yitzhaky A, Weiser M, Hertzberg L. Gene expression meta-analysis reveals the down-regulation of three GABA receptor subunits in the superior temporal gyrus of patients with schizophrenia. Schizophrenia Research. PMID 32376074 DOI: 10.1016/J.Schres.2020.04.027 |
0.405 |
|
| 2020 |
Johnson ECB, Dammer EB, Duong DM, Ping L, Zhou M, Yin L, Higginbotham LA, Guajardo A, White B, Troncoso JC, Thambisetty M, Montine TJ, Lee EB, Trojanowski JQ, Beach TG, ... ... Haroutunian V, et al. Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation. Nature Medicine. PMID 32284590 DOI: 10.1038/S41591-020-0815-6 |
0.35 |
|
| 2020 |
Woo YJ, Roussos P, Haroutunian V, Katsel P, Gandy S, Schadt EE, Zhu J. Comparison of brain connectomes by MRI and genomics and its implication in Alzheimer's disease. Bmc Medicine. 18: 23. PMID 32024511 DOI: 10.1186/S12916-019-1488-1 |
0.326 |
|
| 2020 |
Bai B, Wang X, Li Y, Chen PC, Yu K, Dey KK, Yarbro JM, Han X, Lutz BM, Rao S, Jiao Y, Sifford JM, Han J, Wang M, Tan H, ... ... Haroutunian V, et al. Deep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer's Disease Progression. Neuron. PMID 31926610 DOI: 10.1016/J.Neuron.2019.12.015 |
0.341 |
|
| 2020 |
Wu X, Shukla R, Alganem K, Depasquale E, Reigle J, Simmons M, Hahn C, Haroutunian V, Meller J, Meador-Woodruff J, McCullumsmith R. Transcriptional Profile of Pyramidal Neurons in Chronic Schizophrenia Reveals Lamina-Specific Dysfunction of Neuronal Immunity Biological Psychiatry. 87: S347-S348. DOI: 10.1016/J.Biopsych.2020.02.892 |
0.301 |
|
| 2019 |
Pulina MV, Hopkins M, Haroutunian V, Greengard P, Bustos V. C99 selectively accumulates in vulnerable neurons in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31677937 DOI: 10.1016/J.Jalz.2019.09.002 |
0.329 |
|
| 2019 |
Hoffman GE, Bendl J, Voloudakis G, Montgomery KS, Sloofman L, Wang YC, Shah HR, Hauberg ME, Johnson JS, Girdhar K, Song L, Fullard JF, Kramer R, Hahn CG, Gur R, ... ... Haroutunian V, et al. CommonMind Consortium provides transcriptomic and epigenomic data for Schizophrenia and Bipolar Disorder. Scientific Data. 6: 180. PMID 31551426 DOI: 10.1038/S41597-019-0183-6 |
0.357 |
|
| 2019 |
Fullard JF, Charney AW, Voloudakis G, Uzilov AV, Haroutunian V, Roussos P. Assessment of somatic single-nucleotide variation in brain tissue of cases with schizophrenia. Translational Psychiatry. 9: 21. PMID 30655504 DOI: 10.1038/S41398-018-0342-0 |
0.339 |
|
| 2019 |
Robinson A, Lubitz I, Atrakchi-Baranes D, Licht-Murava A, Katsel P, Leroith D, Liraz-Zaltsman S, Haroutunian V, Beeri MS. Combination of Insulin with a GLP1 Agonist Is Associated with Better Memory and Normal Expression of Insulin Receptor Pathway Genes in a Mouse Model of Alzheimer's Disease. Journal of Molecular Neuroscience : Mn. PMID 30635783 DOI: 10.1007/S12031-019-1257-9 |
0.321 |
|
| 2019 |
Charney A, Fullard J, Hauberg ME, Haroutunian V, Roussos P. Exploring The Somatic Variation In Schizophrenia European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2017.08.283 |
0.373 |
|
| 2018 |
Katsel P, Roussos P, Beeri MS, Gama-Sosa MA, Gandy S, Khan S, Haroutunian V. Parahippocampal gyrus expression of endothelial and insulin receptor signaling pathway genes is modulated by Alzheimer's disease and normalized by treatment with anti-diabetic agents. Plos One. 13: e0206547. PMID 30383799 DOI: 10.1371/Journal.Pone.0206547 |
0.331 |
|
| 2018 |
Sullivan CR, Mielnik CA, O'Donovan SM, Funk AJ, Bentea E, DePasquale EA, Alganem K, Wen Z, Haroutunian V, Katsel P, Ramsey AJ, Meller J, McCullumsmith RE. Connectivity Analyses of Bioenergetic Changes in Schizophrenia: Identification of Novel Treatments. Molecular Neurobiology. PMID 30338483 DOI: 10.1007/S12035-018-1390-4 |
0.398 |
|
| 2018 |
Raj T, Li YI, Wong G, Humphrey J, Wang M, Ramdhani S, Wang YC, Ng B, Gupta I, Haroutunian V, Schadt EE, Young-Pearse T, Mostafavi S, Zhang B, Sklar P, et al. Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility. Nature Genetics. PMID 30297968 DOI: 10.1038/S41588-018-0238-1 |
0.366 |
|
| 2018 |
Wang M, Beckmann ND, Roussos P, Wang E, Zhou X, Wang Q, Ming C, Neff R, Ma W, Fullard JF, Hauberg ME, Bendl J, Peters MA, Logsdon B, Wang P, ... ... Haroutunian V, et al. The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease. Scientific Data. 5: 180185. PMID 30204156 DOI: 10.1038/Sdata.2018.185 |
0.334 |
|
| 2018 |
Bryois J, Garrett ME, Song L, Safi A, Giusti-Rodriguez P, Johnson GD, Shieh AW, Buil A, Fullard JF, Roussos P, Sklar P, Akbarian S, Haroutunian V, Stockmeier CA, Wray GA, et al. Evaluation of chromatin accessibility in prefrontal cortex of individuals with schizophrenia. Nature Communications. 9: 3121. PMID 30087329 DOI: 10.1038/S41467-018-05379-Y |
0.385 |
|
| 2018 |
Readhead B, Haure-Mirande JV, Funk CC, Richards MA, Shannon P, Haroutunian V, Sano M, Liang WS, Beckmann ND, Price ND, Reiman EM, Schadt EE, Ehrlich ME, Gandy S, Dudley JT. Multiscale Analysis of Independent Alzheimer's Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus. Neuron. PMID 29937276 DOI: 10.1016/J.Neuron.2018.05.023 |
0.327 |
|
| 2018 |
Smith RG, Hannon E, De Jager PL, Chibnik L, Lott SJ, Condliffe D, Smith AR, Haroutunian V, Troakes C, Al-Sarraj S, Bennett DA, Powell J, Lovestone S, Schalkwyk L, Mill J, et al. Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29550519 DOI: 10.1016/J.Jalz.2018.01.017 |
0.33 |
|
| 2018 |
Poirel O, Mella S, Videau C, Ramet L, Davoli MA, Herzog E, Katsel P, Mechawar N, Haroutunian V, Epelbaum J, Daumas S, El Mestikawy S. Moderate decline in select synaptic markers in the prefrontal cortex (BA9) of patients with Alzheimer's disease at various cognitive stages. Scientific Reports. 8: 938. PMID 29343737 DOI: 10.1038/S41598-018-19154-Y |
0.353 |
|
| 2017 |
McKenzie AT, Moyon S, Wang M, Katsyv I, Song WM, Zhou X, Dammer EB, Duong DM, Aaker J, Zhao Y, Beckmann N, Wang P, Zhu J, Lah JJ, Seyfried NT, ... ... Haroutunian V, et al. Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer's disease. Molecular Neurodegeneration. 12: 82. PMID 29110684 DOI: 10.1186/S13024-017-0219-3 |
0.327 |
|
| 2017 |
Katsel P, Fam P, Tan W, Khan S, Yang C, Jouroukhin Y, Rudchenko S, Pletnikov MV, Haroutunian V. Overexpression of Truncated Human DISC1 Induces Appearance of Hindbrain Oligodendroglia in the Forebrain During Development. Schizophrenia Bulletin. PMID 28981898 DOI: 10.1093/Schbul/Sbx106 |
0.384 |
|
| 2017 |
Katsel P, Roussos P, Pletnikov M, Haroutunian V. Microvascular anomaly conditions in psychiatric disease. Schizophrenia - angiogenesis connection. Neuroscience and Biobehavioral Reviews. PMID 28396239 DOI: 10.1016/J.Neubiorev.2017.04.003 |
0.371 |
|
| 2017 |
Fullard JF, Giambartolomei C, Hauberg ME, Xu K, Voloudakis G, Shao Z, Bare C, Dudley JT, Mattheisen M, Robakis NK, Haroutunian V, Roussos P. Open chromatin profiling of human postmortem brain infers functional roles for non-coding schizophrenia loci. Human Molecular Genetics. PMID 28335009 DOI: 10.1093/Hmg/Ddx103 |
0.342 |
|
| 2017 |
Chadha R, Haroutunian V, Meador-Woodruff J. SU100. Proteins of the Calcium Transport Machinery at the Endoplasmic Reticulum-Mitochondria Interface are Dysregulated in Schizophrenia Schizophrenia Bulletin. 43: S197-S197. DOI: 10.1093/Schbul/Sbx024.096 |
0.32 |
|
| 2017 |
Kim P, Haroutunian V, Meador-Woodruff J. SU99. Abnormalities in the Secretory Pathway of GPI-Anchored Proteins in Schizophrenia Schizophrenia Bulletin. 43: S197-S197. DOI: 10.1093/Schbul/Sbx024.095 |
0.362 |
|
| 2017 |
Hauberg ME, Fullard J, Giambartolomei C, Xu K, Bare C, Dudley J, Mattheisen M, Pickrell J, Haroutunian V, Roussos P. Cell-Type Specific open Chromatin Profiling in Human Postmortem Brain Infers Functional Roles For Non-Coding Schizophrenia LOCI European Neuropsychopharmacology. 27. DOI: 10.1016/J.Euroneuro.2016.09.483 |
0.355 |
|
| 2016 |
Shively SB, Edgerton SL, Iacono D, Purohit DP, Qu BX, Haroutunian V, Davis KL, Diaz-Arrastia R, Perl DP. Localized cortical chronic traumatic encephalopathy pathology after single, severe axonal injury in human brain. Acta Neuropathologica. PMID 27885490 DOI: 10.1007/S00401-016-1649-7 |
0.356 |
|
| 2016 |
Wang M, Roussos P, McKenzie A, Zhou X, Kajiwara Y, Brennand KJ, De Luca GC, Crary JF, Casaccia P, Buxbaum JD, Ehrlich M, Gandy S, Goate A, Katsel P, Schadt E, ... Haroutunian V, et al. Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer's disease. Genome Medicine. 8: 104. PMID 27799057 DOI: 10.1186/S13073-016-0355-3 |
0.33 |
|
| 2016 |
Mueller TM, Yates SD, Haroutunian V, Meador-Woodruff JH. Altered fucosyltransferase expression in the superior temporal gyrus of elderly patients with schizophrenia. Schizophrenia Research. PMID 27773385 DOI: 10.1016/J.Schres.2016.10.024 |
0.4 |
|
| 2016 |
Fromer M, Roussos P, Sieberts SK, Johnson JS, Kavanagh DH, Perumal TM, Ruderfer DM, Oh EC, Topol A, Shah HR, Klei LL, Kramer R, Pinto D, Gümüş ZH, Cicek AE, ... ... Haroutunian V, et al. Gene expression elucidates functional impact of polygenic risk for schizophrenia. Nature Neuroscience. PMID 27668389 DOI: 10.1038/Nn.4399 |
0.411 |
|
| 2016 |
Pinner AL, Tucholski J, Haroutunian V, McCullumsmith RE, Meador-Woodruff JH. Decreased protein S-palmitoylation in dorsolateral prefrontal cortex in schizophrenia. Schizophrenia Research. PMID 26876311 DOI: 10.1016/J.Schres.2016.01.054 |
0.405 |
|
| 2016 |
Fullard JF, Halene TB, Giambartolomei C, Haroutunian V, Akbarian S, Roussos P. Understanding the genetic liability to schizophrenia through the neuroepigenome. Schizophrenia Research. PMID 26827128 DOI: 10.1016/J.Schres.2016.01.039 |
0.355 |
|
| 2015 |
Bhambhvani HP, Simmons M, Haroutunian V, Meador-Woodruff JH. Decreased expression of cortactin in the schizophrenia brain. Neuroreport. PMID 26691754 DOI: 10.1097/Wnr.0000000000000514 |
0.383 |
|
| 2015 |
Readhead B, Haure-Mirande JV, Zhang B, Haroutunian V, Gandy S, Schadt EE, Dudley JT, Ehrlich ME. Molecular systems evaluation of oligomerogenic APP(E693Q) and fibrillogenic APP(KM670/671NL)/PSEN1(Δexon9) mouse models identifies shared features with human Alzheimer's brain molecular pathology. Molecular Psychiatry. PMID 26552589 DOI: 10.1038/Mp.2015.167 |
0.375 |
|
| 2015 |
McCullumsmith RE, O'Donovan SM, Drummond JB, Benesh FS, Simmons M, Roberts R, Lauriat T, Haroutunian V, Meador-Woodruff JH. Cell-specific abnormalities of glutamate transporters in schizophrenia: sick astrocytes and compensating relay neurons? Molecular Psychiatry. PMID 26416546 DOI: 10.1038/Mp.2015.148 |
0.374 |
|
| 2015 |
Zhu L, Zhong M, Elder GA, Sano M, Holtzman DM, Gandy S, Cardozo C, Haroutunian V, Robakis NK, Cai D. Phospholipid dysregulation contributes to ApoE4-associated cognitive deficits in Alzheimer's disease pathogenesis. Proceedings of the National Academy of Sciences of the United States of America. 112: 11965-70. PMID 26372964 DOI: 10.1073/Pnas.1510011112 |
0.384 |
|
| 2015 |
Mueller TM, Remedies CE, Haroutunian V, Meador-Woodruff JH. Abnormal subcellular localization of GABAA receptor subunits in schizophrenia brain. Translational Psychiatry. 5: e612. PMID 26241350 DOI: 10.1038/Tp.2015.102 |
0.311 |
|
| 2015 |
Scott MR, Rubio MD, Haroutunian V, Meador-Woodruff JH. Protein Expression of Proteasome Subunits in Elderly Patients with Schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26202105 DOI: 10.1038/Npp.2015.219 |
0.406 |
|
| 2015 |
Kippe JM, Mueller TM, Haroutunian V, Meador-Woodruff JH. Abnormal N-acetylglucosaminyltransferase expression in prefrontal cortex in schizophrenia. Schizophrenia Research. PMID 26104473 DOI: 10.1016/J.Schres.2015.06.002 |
0.427 |
|
| 2015 |
O'Donovan SM, Hasselfeld K, Bauer D, Simmons M, Roussos P, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE. Glutamate transporter splice variant expression in an enriched pyramidal cell population in schizophrenia. Translational Psychiatry. 5: e579. PMID 26057049 DOI: 10.1038/Tp.2015.74 |
0.412 |
|
| 2015 |
Sullivan CR, Funk AJ, Shan D, Haroutunian V, McCullumsmith RE. Decreased chloride channel expression in the dorsolateral prefrontal cortex in schizophrenia. Plos One. 10: e0123158. PMID 25826365 DOI: 10.1371/Journal.Pone.0123158 |
0.398 |
|
| 2015 |
Hertzberg L, Katsel P, Roussos P, Haroutunian V, Domany E. Integration of gene expression and GWAS results supports involvement of calcium signaling in Schizophrenia. Schizophrenia Research. 164: 92-9. PMID 25702973 DOI: 10.1016/J.Schres.2015.02.001 |
0.355 |
|
| 2015 |
Bristow GC, Bostrom JA, Haroutunian V, Sodhi MS. Sex differences in GABAergic gene expression occur in the anterior cingulate cortex in schizophrenia. Schizophrenia Research. PMID 25660468 DOI: 10.1016/J.Schres.2015.01.025 |
0.386 |
|
| 2014 |
Roussos P, Katsel P, Fam P, Tan W, Purohit DP, Haroutunian V. The triggering receptor expressed on myeloid cells 2 (TREM2) is associated with enhanced inflammation, neuropathological lesions and increased risk for Alzheimer's dementia. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 25499537 DOI: 10.1016/J.Jalz.2014.10.013 |
0.372 |
|
| 2014 |
Bharadwaj R, Peter CJ, Jiang Y, Roussos P, Vogel-Ciernia A, Shen EY, Mitchell AC, Mao W, Whittle C, Dincer A, Jakovcevski M, Pothula V, Rasmussen TP, Giakoumaki SG, Bitsios P, ... ... Haroutunian V, et al. Conserved higher-order chromatin regulates NMDA receptor gene expression and cognition. Neuron. 84: 997-1008. PMID 25467983 DOI: 10.1016/J.Neuron.2014.10.032 |
0.318 |
|
| 2014 |
Funk AJ, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE. Increased G protein-coupled receptor kinase (GRK) expression in the anterior cingulate cortex in schizophrenia. Schizophrenia Research. 159: 130-5. PMID 25153362 DOI: 10.1016/J.Schres.2014.07.040 |
0.336 |
|
| 2014 |
Lunnon K, Smith R, Hannon E, De Jager PL, Srivastava G, Volta M, Troakes C, Al-Sarraj S, Burrage J, Macdonald R, Condliffe D, Harries LW, Katsel P, Haroutunian V, Kaminsky Z, et al. Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease. Nature Neuroscience. 17: 1164-70. PMID 25129077 DOI: 10.1038/Nn.3782 |
0.362 |
|
| 2014 |
Haroutunian V, Katsel P, Roussos P, Davis KL, Altshuler LL, Bartzokis G. Myelination, oligodendrocytes, and serious mental illness. Glia. 62: 1856-77. PMID 25056210 DOI: 10.1002/Glia.22716 |
0.335 |
|
| 2014 |
Jun G, Asai H, Zeldich E, Drapeau E, Chen C, Chung J, Park JH, Kim S, Haroutunian V, Foroud T, Kuwano R, Haines JL, Pericak-Vance MA, Schellenberg GD, Lunetta KL, et al. PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation. Annals of Neurology. 76: 379-92. PMID 25043464 DOI: 10.1002/Ana.24219 |
0.304 |
|
| 2014 |
McGuire JL, Hammond JH, Yates SD, Chen D, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE. Altered serine/threonine kinase activity in schizophrenia. Brain Research. 1568: 42-54. PMID 24780530 DOI: 10.1016/J.Brainres.2014.04.029 |
0.339 |
|
| 2014 |
Pinner AL, Haroutunian V, Meador-Woodruff JH. Alterations of the myristoylated, alanine-rich C kinase substrate (MARCKS) in prefrontal cortex in schizophrenia. Schizophrenia Research. 154: 36-41. PMID 24568864 DOI: 10.1016/J.Schres.2014.02.003 |
0.413 |
|
| 2014 |
Shan D, Mount D, Moore S, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE. Abnormal partitioning of hexokinase 1 suggests disruption of a glutamate transport protein complex in schizophrenia. Schizophrenia Research. 154: 1-13. PMID 24560881 DOI: 10.1016/J.Schres.2014.01.028 |
0.328 |
|
| 2014 |
Roussos P, Haroutunian V. Schizophrenia: susceptibility genes and oligodendroglial and myelin related abnormalities. Frontiers in Cellular Neuroscience. 8: 5. PMID 24478629 DOI: 10.3389/Fncel.2014.00005 |
0.385 |
|
| 2014 |
Huynh JL, Garg P, Thin TH, Yoo S, Dutta R, Trapp BD, Haroutunian V, Zhu J, Donovan MJ, Sharp AJ, Casaccia P. Epigenome-wide differences in pathology-free regions of multiple sclerosis-affected brains. Nature Neuroscience. 17: 121-30. PMID 24270187 DOI: 10.1038/Nn.3588 |
0.312 |
|
| 2014 |
Mueller TM, Haroutunian V, Meador-Woodruff JH. N-Glycosylation of GABAA receptor subunits is altered in Schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 528-37. PMID 23917429 DOI: 10.1038/Npp.2013.190 |
0.384 |
|
| 2014 |
Akbarian S, Lin CL, Dincer A, Giannaris EL, Guo Y, Akintobe A, Neary J, Haroutunian V, Lessard A, Bunney WE, Straubhaar J, Hemby SE, Akbarian S. SUBCORTICAL WHITE MATTER NEURONS IN AUTISM, SCHIZOPHRENIA AND DEPRESSION Schizophrenia Research. 153: S27-S28. DOI: 10.1016/S0920-9964(14)70091-X |
0.318 |
|
| 2014 |
Haroutunian V. A Systems Biology Approach Toward Understanding Schizophrenia Schizophrenia Research. 153. DOI: 10.1016/S0920-9964(14)70031-3 |
0.323 |
|
| 2014 |
Siever LJ, Rosell D, McClure M, Strike K, Barch DM, Harvey P, Girgis R, Lieberman J, Giakoumaki S, Bitsios P, Roussos P, Haroutunian V. THE D1 RECEPTOR AND COGNITION AND TRIAL OF A NOVEL D1 AGONIST IN THE SCHIZOPHRENIA SPECTRUM Schizophrenia Research. 153: S5-S6. DOI: 10.1016/S0920-9964(14)70017-9 |
0.327 |
|
| 2013 |
Mamdani M, McMichael GO, Gadepalli V, Williamson V, Parker EK, Haroutunian V, Vladimirov VI. Differential regulation of schizophrenia-associated microRNA gene function by variable number tandem repeats (VNTR) polymorphism. Schizophrenia Research. 151: 284-6. PMID 24210531 DOI: 10.1016/J.Schres.2013.10.024 |
0.327 |
|
| 2013 |
Katsel P, Tan W, Fam P, Purohit DP, Haroutunian V. Cell cycle checkpoint abnormalities during dementia: A plausible association with the loss of protection against oxidative stress in Alzheimer's disease [corrected]. Plos One. 8: e68361. PMID 23861893 DOI: 10.1371/Journal.Pone.0068361 |
0.305 |
|
| 2013 |
Tucholski J, Simmons MS, Pinner AL, McMillan LD, Haroutunian V, Meador-Woodruff JH. N-linked glycosylation of cortical N-methyl-D-aspartate and kainate receptor subunits in schizophrenia. Neuroreport. 24: 688-91. PMID 23820740 DOI: 10.1097/Wnr.0B013E328363Bd8A |
0.383 |
|
| 2013 |
Rubio MD, Wood K, Haroutunian V, Meador-Woodruff JH. Dysfunction of the ubiquitin proteasome and ubiquitin-like systems in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 1910-20. PMID 23571678 DOI: 10.1038/Npp.2013.84 |
0.383 |
|
| 2013 |
Drummond JB, Tucholski J, Haroutunian V, Meador-Woodruff JH. Transmembrane AMPA receptor regulatory protein (TARP) dysregulation in anterior cingulate cortex in schizophrenia. Schizophrenia Research. 147: 32-8. PMID 23566497 DOI: 10.1016/J.Schres.2013.03.010 |
0.438 |
|
| 2013 |
Tucholski J, Simmons MS, Pinner AL, Haroutunian V, McCullumsmith RE, Meador-Woodruff JH. Abnormal N-linked glycosylation of cortical AMPA receptor subunits in schizophrenia. Schizophrenia Research. 146: 177-83. PMID 23462048 DOI: 10.1016/J.Schres.2013.01.031 |
0.397 |
|
| 2013 |
Gandy S, Haroutunian V, DeKosky ST, Sano M, Schadt EE. CR1 and the "vanishing amyloid" hypothesis of Alzheimer's disease. Biological Psychiatry. 73: 393-5. PMID 23399469 DOI: 10.1016/J.Biopsych.2013.01.013 |
0.336 |
|
| 2013 |
Shan D, Lucas EK, Drummond JB, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE. Abnormal expression of glutamate transporters in temporal lobe areas in elderly patients with schizophrenia. Schizophrenia Research. 144: 1-8. PMID 23356950 DOI: 10.1016/J.Schres.2012.12.019 |
0.389 |
|
| 2013 |
Zhao W, Ho L, Varghese M, Yemul S, Dams-O'Connor K, Gordon W, Knable L, Freire D, Haroutunian V, Pasinetti GM. Decreased level of olfactory receptors in blood cells following traumatic brain injury and potential association with tauopathy. Journal of Alzheimer's Disease : Jad. 34: 417-29. PMID 23241557 DOI: 10.3233/Jad-121894 |
0.307 |
|
| 2013 |
Roussos P, Katsel P, Davis KL, Giakoumaki SG, Lencz T, Malhotra AK, Siever LJ, Bitsios P, Haroutunian V. Convergent findings for abnormalities of the NF-κB signaling pathway in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 533-9. PMID 23132271 DOI: 10.1038/Npp.2012.215 |
0.329 |
|
| 2012 |
Drummond JB, Simmons M, Haroutunian V, Meador-Woodruff JH. Upregulation of cornichon transcripts in the dorsolateral prefrontal cortex in schizophrenia. Neuroreport. 23: 1031-4. PMID 23103966 DOI: 10.1097/Wnr.0B013E32835Ad229 |
0.446 |
|
| 2012 |
Roussos P, Katsel P, Davis KL, Siever LJ, Haroutunian V. A system-level transcriptomic analysis of schizophrenia using postmortem brain tissue samples. Archives of General Psychiatry. 69: 1205-13. PMID 22868662 DOI: 10.1001/Archgenpsychiatry.2012.704 |
0.413 |
|
| 2012 |
Carty NC, Xu J, Kurup P, Brouillette J, Goebel-Goody SM, Austin DR, Yuan P, Chen G, Correa PR, Haroutunian V, Pittenger C, Lombroso PJ. The tyrosine phosphatase STEP: implications in schizophrenia and the molecular mechanism underlying antipsychotic medications. Translational Psychiatry. 2: e137. PMID 22781170 DOI: 10.1038/Tp.2012.63 |
0.401 |
|
| 2012 |
Hammond JC, Meador-Woodruff JH, Haroutunian V, McCullumsmith RE. AMPA receptor subunit expression in the endoplasmic reticulum in frontal cortex of elderly patients with schizophrenia. Plos One. 7: e39190. PMID 22720072 DOI: 10.1371/Journal.Pone.0039190 |
0.408 |
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| 2012 |
Ho L, Yemul S, Knable L, Katsel P, Zhao R, Haroutunian V, Pasinetti GM. Insulin receptor expression and activity in the brains of nondiabetic sporadic Alzheimer's disease cases. International Journal of Alzheimer's Disease. 2012: 321280. PMID 22666619 DOI: 10.1155/2012/321280 |
0.334 |
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| 2012 |
Ho L, Zhao W, Dams-O'Connor K, Tang CY, Gordon W, Peskind ER, Yemul S, Haroutunian V, Pasinetti GM. Elevated plasma MCP-1 concentration following traumatic brain injury as a potential "predisposition" factor associated with an increased risk for subsequent development of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 31: 301-13. PMID 22543850 DOI: 10.3233/Jad-2012-120598 |
0.328 |
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| 2012 |
Nelson PT, Alafuzoff I, Bigio EH, Bouras C, Braak H, Cairns NJ, Castellani RJ, Crain BJ, Davies P, Del Tredici K, Duyckaerts C, Frosch MP, Haroutunian V, Hof PR, Hulette CM, et al. Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature. Journal of Neuropathology and Experimental Neurology. 71: 362-81. PMID 22487856 DOI: 10.1097/Nen.0B013E31825018F7 |
0.331 |
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| 2012 |
Rubio MD, Haroutunian V, Meador-Woodruff JH. Abnormalities of the Duo/Ras-related C3 botulinum toxin substrate 1/p21-activated kinase 1 pathway drive myosin light chain phosphorylation in frontal cortex in schizophrenia. Biological Psychiatry. 71: 906-14. PMID 22458949 DOI: 10.1016/J.Biopsych.2012.02.006 |
0.4 |
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| 2012 |
Shan D, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE. Expression of equilibrative nucleoside transporter type 1 protein in elderly patients with schizophrenia. Neuroreport. 23: 224-7. PMID 22314683 DOI: 10.1097/Wnr.0B013E3283500987 |
0.418 |
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| 2012 |
Moehle MS, Luduena RF, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE. Regional differences in expression of β-tubulin isoforms in schizophrenia. Schizophrenia Research. 135: 181-6. PMID 22264600 DOI: 10.1016/J.Schres.2011.12.010 |
0.431 |
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| 2012 |
Beeri MS, Haroutunian V, Schmeidler J, Sano M, Fam P, Kavanaugh A, Barr AM, Honer WG, Katsel P. Synaptic protein deficits are associated with dementia irrespective of extreme old age. Neurobiology of Aging. 33: 1125.e1-8. PMID 22206847 DOI: 10.1016/J.Neurobiolaging.2011.08.017 |
0.345 |
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| 2012 |
Funk AJ, McCullumsmith RE, Haroutunian V, Meador-Woodruff JH. Abnormal activity of the MAPK- and cAMP-associated signaling pathways in frontal cortical areas in postmortem brain in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 896-905. PMID 22048463 DOI: 10.1038/Npp.2011.267 |
0.401 |
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| 2012 |
Roussos P, Katsel P, Davis KL, Bitsios P, Giakoumaki SG, Jogia J, Rozsnyai K, Collier D, Frangou S, Siever LJ, Haroutunian V. Molecular and genetic evidence for abnormalities in the nodes of Ranvier in schizophrenia. Archives of General Psychiatry. 69: 7-15. PMID 21893642 DOI: 10.1001/Archgenpsychiatry.2011.110 |
0.312 |
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| 2012 |
Akram A, Schmeidler J, Katsel P, Hof PR, Haroutunian V. Association of ApoE and LRP mRNA levels with dementia and AD neuropathology. Neurobiology of Aging. 33: 628.e1-628.e14. PMID 21676498 DOI: 10.1016/J.Neurobiolaging.2011.04.010 |
0.379 |
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| 2012 |
Beeri MS, Schmeidler J, Lesser GT, Maroukian M, West R, Leung S, Wysocki M, Perl DP, Purohit DP, Haroutunian V. Corticosteroids, but not NSAIDs, are associated with less Alzheimer neuropathology. Neurobiology of Aging. 33: 1258-64. PMID 21458888 DOI: 10.1016/J.Neurobiolaging.2011.02.011 |
0.327 |
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| 2012 |
Rubio MD, Haroutunian V, Meador-Woodruff JH. Poster #136 DISRUPTION OF CDC42 AND DUO/PAK1 PATHWAY DRIVES MYOSIN LIGHT CHAIN PHOSPHORYLATION IN SCHIZOPHRENIA Schizophrenia Research. 136: S140. DOI: 10.1016/S0920-9964(12)70450-4 |
0.304 |
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| 2012 |
Haroutunian V. Similarities In The Gene And Protein Expression Substrates Of Schizophrenia And Bipolar Disorder Schizophrenia Research. 136. DOI: 10.1016/S0920-9964(12)70028-2 |
0.361 |
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| 2011 |
Xu H, Haroutunian V, Bartzokis G, Shenton ME. Oligodendrocytes in schizophrenia. Schizophrenia Research and Treatment. 2011: 249768. PMID 22937262 DOI: 10.1155/2011/249768 |
0.405 |
|
| 2011 |
Katsel P, Tan W, Abazyan B, Davis KL, Ross C, Pletnikov MV, Haroutunian V. Expression of mutant human DISC1 in mice supports abnormalities in differentiation of oligodendrocytes. Schizophrenia Research. 130: 238-49. PMID 21605958 DOI: 10.1016/J.Schres.2011.04.021 |
0.386 |
|
| 2011 |
Hammond JC, McCullumsmith RE, Haroutunian V, Meador-Woodruff JH. Endosomal trafficking of AMPA receptors in frontal cortex of elderly patients with schizophrenia. Schizophrenia Research. 130: 260-5. PMID 21576009 DOI: 10.1016/J.Schres.2011.04.029 |
0.421 |
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| 2011 |
Sodhi MS, Simmons M, McCullumsmith R, Haroutunian V, Meador-Woodruff JH. Glutamatergic gene expression is specifically reduced in thalamocortical projecting relay neurons in schizophrenia. Biological Psychiatry. 70: 646-54. PMID 21549355 DOI: 10.1016/J.Biopsych.2011.02.022 |
0.404 |
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| 2011 |
Radu A, Hristescu G, Katsel P, Haroutunian V, Davis KL. Microarray database mining and cell differentiation defects in schizophrenia. Advances in Experimental Medicine and Biology. 696: 67-74. PMID 21431547 DOI: 10.1007/978-1-4419-7046-6_7 |
0.371 |
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| 2011 |
Katsel P, Byne W, Roussos P, Tan W, Siever L, Haroutunian V. Astrocyte and glutamate markers in the superficial, deep, and white matter layers of the anterior cingulate gyrus in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 1171-7. PMID 21270770 DOI: 10.1038/Npp.2010.252 |
0.409 |
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| 2011 |
Horesh Y, Katsel P, Haroutunian V, Domany E. Gene expression signature is shared by patients with Alzheimer's disease and schizophrenia at the superior temporal gyrus. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 18: 410-24. PMID 20695885 DOI: 10.1111/J.1468-1331.2010.03166.X |
0.42 |
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| 2011 |
Deep-Soboslay A, Benes FM, Haroutunian V, Ellis JK, Kleinman JE, Hyde TM. Psychiatric brain banking: three perspectives on current trends and future directions. Biological Psychiatry. 69: 104-12. PMID 20673875 DOI: 10.1016/J.Biopsych.2010.05.025 |
0.323 |
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| 2010 |
Lyddon R, Cuppen E, Haroutunian V, Siever LJ, Dracheva S. No link of serotonin 2C receptor editing to serotonin transporter genotype. Neuroreport. 21: 1080-4. PMID 20948451 DOI: 10.1097/Wnr.0B013E32834052F0 |
0.751 |
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| 2010 |
Gong B, Chen F, Pan Y, Arrieta-Cruz I, Yoshida Y, Haroutunian V, Pasinetti GM. SCFFbx2-E3-ligase-mediated degradation of BACE1 attenuates Alzheimer's disease amyloidosis and improves synaptic function. Aging Cell. 9: 1018-31. PMID 20854419 DOI: 10.1111/J.1474-9726.2010.00632.X |
0.391 |
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| 2010 |
Kerns D, Vong GS, Barley K, Dracheva S, Katsel P, Casaccia P, Haroutunian V, Byne W. Gene expression abnormalities and oligodendrocyte deficits in the internal capsule in schizophrenia. Schizophrenia Research. 120: 150-8. PMID 20580881 DOI: 10.1016/J.Schres.2010.04.012 |
0.663 |
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| 2010 |
Hammond JC, McCullumsmith RE, Funk AJ, Haroutunian V, Meador-Woodruff JH. Evidence for abnormal forward trafficking of AMPA receptors in frontal cortex of elderly patients with schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 2110-9. PMID 20571483 DOI: 10.1038/Npp.2010.87 |
0.408 |
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| 2010 |
Kristiansen LV, Bakir B, Haroutunian V, Meador-Woodruff JH. Expression of the NR2B-NMDA receptor trafficking complex in prefrontal cortex from a group of elderly patients with schizophrenia. Schizophrenia Research. 119: 198-209. PMID 20347576 DOI: 10.1016/J.Schres.2010.02.1069 |
0.425 |
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| 2010 |
Kajiwara Y, Franciosi S, Takahashi N, Krug L, Schmeidler J, Taddei K, Haroutunian V, Fried U, Ehrlich M, Martins RN, Gandy S, Buxbaum JD. Extensive proteomic screening identifies the obesity-related NYGGF4 protein as a novel LRP1-interactor, showing reduced expression in early Alzheimer's disease. Molecular Neurodegeneration. 5: 1. PMID 20205790 DOI: 10.1186/1750-1326-5-1 |
0.335 |
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| 2010 |
Kristiansen LV, Patel SA, Haroutunian V, Meador-Woodruff JH. Expression of the NR2B-NMDA receptor subunit and its Tbr-1/CINAP regulatory proteins in postmortem brain suggest altered receptor processing in schizophrenia. Synapse (New York, N.Y.). 64: 495-502. PMID 20175224 DOI: 10.1002/Syn.20754 |
0.424 |
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| 2010 |
Akram A, Schmeidler J, Katsel P, Hof PR, Haroutunian V. Increased expression of cholesterol transporter ABCA1 is highly correlated with severity of dementia in AD hippocampus. Brain Research. 1318: 167-77. PMID 20079340 DOI: 10.1016/J.Brainres.2010.01.006 |
0.364 |
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| 2010 |
Rapp MA, Schnaider-Beeri M, Purohit DP, Reichenberg A, McGurk SR, Haroutunian V, Harvey PD. Cortical neuritic plaques and hippocampal neurofibrillary tangles are related to dementia severity in elderly schizophrenia patients. Schizophrenia Research. 116: 90-6. PMID 19896333 DOI: 10.1016/J.Schres.2009.10.013 |
0.395 |
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| 2010 |
Bauer D, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE. Abnormal glycosylation of EAAT1 and EAAT2 in prefrontal cortex of elderly patients with schizophrenia. Schizophrenia Research. 117: 92-8. PMID 19716271 DOI: 10.1016/J.Schres.2009.07.025 |
0.396 |
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| 2010 |
Segal D, Carpenter D, Höistad M, Haroutunian V, Tang CY, Hof PR. Cingulum bundle white matter in mag-knockout mice Translational Neuroscience. 1: 131-138. DOI: 10.2478/V10134-010-0019-6 |
0.351 |
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| 2009 |
Katsel P, Tan W, Haroutunian V. Gain in brain immunity in the oldest-old differentiates cognitively normal from demented individuals. Plos One. 4: e7642. PMID 19865478 DOI: 10.1371/Journal.Pone.0007642 |
0.333 |
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| 2009 |
Kajiwara Y, Akram A, Katsel P, Haroutunian V, Schmeidler J, Beecham G, Haines JL, Pericak-Vance MA, Buxbaum JD. FE65 binds Teashirt, inhibiting expression of the primate-specific caspase-4. Plos One. 4: e5071. PMID 19343227 DOI: 10.1371/Journal.Pone.0005071 |
0.344 |
|
| 2009 |
Qin W, Haroutunian V, Katsel P, Cardozo CP, Ho L, Buxbaum JD, Pasinetti GM. PGC-1alpha expression decreases in the Alzheimer disease brain as a function of dementia. Archives of Neurology. 66: 352-61. PMID 19273754 DOI: 10.1001/Archneurol.2008.588 |
0.328 |
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| 2009 |
Amadio M, Pascale A, Wang J, Ho L, Quattrone A, Gandy S, Haroutunian V, Racchi M, Pasinetti GM. nELAV proteins alteration in Alzheimer's disease brain: a novel putative target for amyloid-beta reverberating on AbetaPP processing. Journal of Alzheimer's Disease : Jad. 16: 409-19. PMID 19221430 DOI: 10.3233/Jad-2009-0967 |
0.357 |
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| 2009 |
Bauer DE, Haroutunian V, McCullumsmith RE, Meador-Woodruff JH. Expression of four housekeeping proteins in elderly patients with schizophrenia. Journal of Neural Transmission (Vienna, Austria : 1996). 116: 487-91. PMID 19139805 DOI: 10.1007/S00702-008-0143-3 |
0.398 |
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| 2009 |
Haroutunian V, Katsel P, Schmeidler J. Transcriptional vulnerability of brain regions in Alzheimer's disease and dementia. Neurobiology of Aging. 30: 561-73. PMID 17845826 DOI: 10.1016/J.Neurobiolaging.2007.07.021 |
0.37 |
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| 2009 |
Naj AC, Beecham GW, Slifer MA, Martin ER, Gallins PJ, Konidari I, Whitehead PL, Cai G, Kajiwara Y, Haroutunian V, Gwirtsman HE, Gilbert JR, Haines JL, Buxbaum JD, Pericak-Vance MA. Genome-wide association study validates associations in APOE, VDR, SORL1, WWC1, and ELAVL4 and identifies novel candidate genes for late-onset Alzheimer's disease Alzheimers & Dementia. 5. DOI: 10.1016/J.Jalz.2009.05.519 |
0.302 |
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| 2009 |
Beecham GW, Naj AC, Cai G, Kajiwara Y, Haroutunian V, Konidari I, Gallins P, Whitehead P, Gilbert JR, Slifer MA, Gwirstman H, Martin ER, Buxbaum J, Haines JL, Pericak-Vance MA. GRB-associated binding protein 2 (GAB2) interacts with APOE to alter risk of late-onset Alzheimer's disease Alzheimers & Dementia. 5: 111. DOI: 10.1016/J.Jalz.2009.05.348 |
0.309 |
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| 2008 |
Rao MV, Mohan PS, Peterhoff CM, Yang DS, Schmidt SD, Stavrides PH, Campbell J, Chen Y, Jiang Y, Paskevich PA, Cataldo AM, Haroutunian V, Nixon RA. Marked calpastatin (CAST) depletion in Alzheimer's disease accelerates cytoskeleton disruption and neurodegeneration: neuroprotection by CAST overexpression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 12241-54. PMID 19020018 DOI: 10.1523/Jneurosci.4119-08.2008 |
0.327 |
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| 2008 |
Haroutunian V, Schnaider-Beeri M, Schmeidler J, Wysocki M, Purohit DP, Perl DP, Libow LS, Lesser GT, Maroukian M, Grossman HT. Role of the neuropathology of Alzheimer disease in dementia in the oldest-old. Archives of Neurology. 65: 1211-7. PMID 18779425 DOI: 10.1001/Archneur.65.9.1211 |
0.319 |
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| 2008 |
Steffek AE, McCullumsmith RE, Haroutunian V, Meador-Woodruff JH. Cortical expression of glial fibrillary acidic protein and glutamine synthetase is decreased in schizophrenia. Schizophrenia Research. 103: 71-82. PMID 18562176 DOI: 10.1016/J.Schres.2008.04.032 |
0.433 |
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| 2008 |
Dracheva S, Byne W, Chin B, Haroutunian V. Ionotropic glutamate receptor mRNA expression in the human thalamus: absence of change in schizophrenia. Brain Research. 1214: 23-34. PMID 18462708 DOI: 10.1016/J.Brainres.2008.03.039 |
0.688 |
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| 2008 |
Schnaider Beeri M, Silverman JM, Schmeidler J, Wysocki M, Grossman HZ, Purohit DP, Perl DP, Haroutunian V. Clinical dementia rating performed several years prior to death predicts regional Alzheimer's neuropathology. Dementia and Geriatric Cognitive Disorders. 25: 392-8. PMID 18367838 DOI: 10.1159/000122586 |
0.311 |
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| 2008 |
Katsel P, Davis KL, Li C, Tan W, Greenstein E, Kleiner Hoffman LB, Haroutunian V. Abnormal indices of cell cycle activity in schizophrenia and their potential association with oligodendrocytes. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 2993-3009. PMID 18322470 DOI: 10.1038/Npp.2008.19 |
0.366 |
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| 2008 |
Dracheva S, Chin B, Haroutunian V. Altered serotonin 2C receptor RNA splicing in suicide: association with editing. Neuroreport. 19: 379-82. PMID 18303585 DOI: 10.1097/Wnr.0B013E3282F556D2 |
0.647 |
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| 2008 |
Rapp MA, Schnaider-Beeri M, Purohit DP, Perl DP, Haroutunian V, Sano M. Increased neurofibrillary tangles in patients with Alzheimer disease with comorbid depression. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 16: 168-74. PMID 18239198 DOI: 10.1097/Jgp.0B013E31816029Ec |
0.312 |
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| 2008 |
Oni-Orisan A, Kristiansen LV, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE. Altered vesicular glutamate transporter expression in the anterior cingulate cortex in schizophrenia. Biological Psychiatry. 63: 766-75. PMID 18155679 DOI: 10.1016/J.Biopsych.2007.10.020 |
0.424 |
|
| 2008 |
Byne W, Dracheva S, Chin B, Schmeidler JM, Davis KL, Haroutunian V. Schizophrenia and sex associated differences in the expression of neuronal and oligodendrocyte-specific genes in individual thalamic nuclei. Schizophrenia Research. 98: 118-28. PMID 18029146 DOI: 10.1016/J.Schres.2007.09.034 |
0.676 |
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| 2008 |
Lauriat TL, Shiue L, Haroutunian V, Verbitsky M, Ares M, Ospina L, McInnes LA. Developmental expression profile of quaking, a candidate gene for schizophrenia, and its target genes in human prefrontal cortex and hippocampus shows regional specificity. Journal of Neuroscience Research. 86: 785-96. PMID 17918747 DOI: 10.1002/Jnr.21534 |
0.405 |
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| 2008 |
Dracheva S, Patel N, Woo DA, Marcus SM, Siever LJ, Haroutunian V. Increased serotonin 2C receptor mRNA editing: a possible risk factor for suicide. Molecular Psychiatry. 13: 1001-10. PMID 17848916 DOI: 10.1038/Sj.Mp.4002081 |
0.641 |
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| 2008 |
Baker DA, Madayag A, Kristiansen LV, Meador-Woodruff JH, Haroutunian V, Raju I. Contribution of cystine-glutamate antiporters to the psychotomimetic effects of phencyclidine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 1760-72. PMID 17728701 DOI: 10.1038/Sj.Npp.1301532 |
0.343 |
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| 2007 |
Haroutunian V, Davis KL. Introduction to the special section: Myelin and oligodendrocyte abnormalities in schizophrenia. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 10: 499-502. PMID 17583597 DOI: 10.1017/S1461145706007449 |
0.376 |
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| 2007 |
Katsel P, Li C, Haroutunian V. Gene expression alterations in the sphingolipid metabolism pathways during progression of dementia and Alzheimer's disease: a shift toward ceramide accumulation at the earliest recognizable stages of Alzheimer's disease? Neurochemical Research. 32: 845-56. PMID 17342407 DOI: 10.1007/S11064-007-9297-X |
0.344 |
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| 2007 |
Haroutunian V, Katsel P, Dracheva S, Stewart DG, Davis KL. Variations in oligodendrocyte-related gene expression across multiple cortical regions: implications for the pathophysiology of schizophrenia. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 10: 565-73. PMID 17291370 DOI: 10.1017/S1461145706007310 |
0.687 |
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| 2007 |
McCullumsmith RE, Gupta D, Beneyto M, Kreger E, Haroutunian V, Davis KL, Meador-Woodruff JH. Expression of transcripts for myelination-related genes in the anterior cingulate cortex in schizophrenia. Schizophrenia Research. 90: 15-27. PMID 17223013 DOI: 10.1016/J.Schres.2006.11.017 |
0.399 |
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| 2007 |
Yakovleva T, Marinova Z, Kuzmin A, Seidah NG, Haroutunian V, Terenius L, Bakalkin G. Dysregulation of dynorphins in Alzheimer disease. Neurobiology of Aging. 28: 1700-8. PMID 16914231 DOI: 10.1016/J.Neurobiolaging.2006.07.002 |
0.326 |
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| 2007 |
Gill SK, Ishak M, Dobransky T, Haroutunian V, Davis KL, Rylett RJ. 82-kDa choline acetyltransferase is in nuclei of cholinergic neurons in human CNS and altered in aging and Alzheimer disease. Neurobiology of Aging. 28: 1028-40. PMID 16797789 DOI: 10.1016/J.Neurobiolaging.2006.05.011 |
0.355 |
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| 2007 |
Zhao Z, Xiang Z, Haroutunian V, Buxbaum JD, Stetka B, Pasinetti GM. Insulin degrading enzyme activity selectively decreases in the hippocampal formation of cases at high risk to develop Alzheimer's disease. Neurobiology of Aging. 28: 824-30. PMID 16769157 DOI: 10.1016/J.Neurobiolaging.2006.05.001 |
0.328 |
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| 2007 |
Haroutunian V, Davies P, Vianna C, Buxbaum JD, Purohit DP. Tau protein abnormalities associated with the progression of alzheimer disease type dementia. Neurobiology of Aging. 28: 1-7. PMID 16343696 DOI: 10.1016/J.Neurobiolaging.2005.11.001 |
0.356 |
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| 2006 |
Haroutunian V, Katsel P, Dracheva S, Davis KL. The human homolog of the QKI gene affected in the severe dysmyelination "quaking" mouse phenotype: downregulated in multiple brain regions in schizophrenia. The American Journal of Psychiatry. 163: 1834-7. PMID 17012699 DOI: 10.1176/Ajp.2006.163.10.1834 |
0.699 |
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| 2006 |
Lauriat TL, Dracheva S, Kremerskothen J, Duning K, Haroutunian V, Buxbaum JD, Hyde TM, Kleinman JE, McInnes LA. Characterization of KIAA0513, a novel signaling molecule that interacts with modulators of neuroplasticity, apoptosis, and the cytoskeleton. Brain Research. 1121: 1-11. PMID 17010949 DOI: 10.1016/J.Brainres.2006.08.099 |
0.667 |
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| 2006 |
Georgieva L, Moskvina V, Peirce T, Norton N, Bray NJ, Jones L, Holmans P, Macgregor S, Zammit S, Wilkinson J, Williams H, Nikolov I, Williams N, Ivanov D, Davis KL, ... Haroutunian V, et al. Convergent evidence that oligodendrocyte lineage transcription factor 2 (OLIG2) and interacting genes influence susceptibility to schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 103: 12469-74. PMID 16891421 DOI: 10.1073/Pnas.0603029103 |
0.377 |
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| 2006 |
Steffek AE, Haroutunian V, Meador-Woodruff JH. Serine racemase protein expression in cortex and hippocampus in schizophrenia. Neuroreport. 17: 1181-5. PMID 16837850 DOI: 10.1097/01.Wnr.0000230512.01339.72 |
0.406 |
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| 2006 |
Religa D, Strozyk D, Cherny RA, Volitakis I, Haroutunian V, Winblad B, Naslund J, Bush AI. Elevated cortical zinc in Alzheimer disease. Neurology. 67: 69-75. PMID 16832080 DOI: 10.1212/01.Wnl.0000223644.08653.B5 |
0.381 |
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| 2006 |
Baracskay KL, Haroutunian V, Meador-Woodruff JH. Dopamine receptor signaling molecules are altered in elderly schizophrenic cortex. Synapse (New York, N.Y.). 60: 271-9. PMID 16786528 DOI: 10.1002/Syn.20292 |
0.38 |
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| 2006 |
Clinton SM, Haroutunian V, Meador-Woodruff JH. Up-regulation of NMDA receptor subunit and post-synaptic density protein expression in the thalamus of elderly patients with schizophrenia. Journal of Neurochemistry. 98: 1114-25. PMID 16762023 DOI: 10.1111/J.1471-4159.2006.03954.X |
0.418 |
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| 2006 |
Byne W, Kidkardnee S, Tatusov A, Yiannoulos G, Buchsbaum MS, Haroutunian V. Schizophrenia-associated reduction of neuronal and oligodendrocyte numbers in the anterior principal thalamic nucleus. Schizophrenia Research. 85: 245-53. PMID 16730162 DOI: 10.1016/J.Schres.2006.03.029 |
0.317 |
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| 2006 |
Kristiansen LV, Beneyto M, Haroutunian V, Meador-Woodruff JH. Changes in NMDA receptor subunits and interacting PSD proteins in dorsolateral prefrontal and anterior cingulate cortex indicate abnormal regional expression in schizophrenia. Molecular Psychiatry. 11: 737-47, 705. PMID 16702973 DOI: 10.1038/Sj.Mp.4001844 |
0.421 |
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| 2006 |
Zhao Z, Ksiezak-Reding H, Riggio S, Haroutunian V, Pasinetti GM. Insulin receptor deficits in schizophrenia and in cellular and animal models of insulin receptor dysfunction. Schizophrenia Research. 84: 1-14. PMID 16581231 DOI: 10.1016/J.Schres.2006.02.009 |
0.338 |
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| 2006 |
Huerta I, McCullumsmith RE, Haroutunian V, Giménez-Amaya JM, Meador-Woodruff JH. Expression of excitatory amino acid transporter interacting protein transcripts in the thalamus in schizophrenia. Synapse (New York, N.Y.). 59: 394-402. PMID 16485262 DOI: 10.1002/Syn.20250 |
0.404 |
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| 2006 |
Xiang Z, Haroutunian V, Ho L, Purohit D, Pasinetti GM. Microglia activation in the brain as inflammatory biomarker of Alzheimer's disease neuropathology and clinical dementia. Disease Markers. 22: 95-102. PMID 16410654 DOI: 10.1155/2006/276239 |
0.318 |
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| 2006 |
Prohovnik I, Perl DP, Davis KL, Libow L, Lesser G, Haroutunian V. Dissociation of neuropathology from severity of dementia in late-onset Alzheimer disease. Neurology. 66: 49-55. PMID 16401845 DOI: 10.1212/01.Wnl.0000191298.68045.50 |
0.322 |
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| 2006 |
Peirce TR, Bray NJ, Williams NM, Norton N, Moskvina V, Preece A, Haroutunian V, Buxbaum JD, Owen MJ, O'Donovan MC. Convergent evidence for 2',3'-cyclic nucleotide 3'-phosphodiesterase as a possible susceptibility gene for schizophrenia. Archives of General Psychiatry. 63: 18-24. PMID 16389193 DOI: 10.1001/Archpsyc.63.1.18 |
0.423 |
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| 2006 |
Lauriat TL, Dracheva S, Chin B, Schmeidler J, McInnes LA, Haroutunian V. Quantitative analysis of glutamate transporter mRNA expression in prefrontal and primary visual cortex in normal and schizophrenic brain. Neuroscience. 137: 843-51. PMID 16297566 DOI: 10.1016/J.Neuroscience.2005.10.003 |
0.678 |
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| 2006 |
Dracheva S, Davis KL, Chin B, Woo DA, Schmeidler J, Haroutunian V. Myelin-associated mRNA and protein expression deficits in the anterior cingulate cortex and hippocampus in elderly schizophrenia patients. Neurobiology of Disease. 21: 531-40. PMID 16213148 DOI: 10.1016/J.Nbd.2005.08.012 |
0.703 |
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| 2006 |
Kristiansen LV, Beneyto M, Haroutunian V, Meador-Woodruff JH. Altered NMDA receptor expression in schizophrenia Molecular Psychiatry. 11: 705. DOI: 10.1038/Sj.Mp.4001871 |
0.386 |
|
| 2005 |
Clinton SM, Ibrahim HM, Frey KA, Davis KL, Haroutunian V, Meador-Woodruff JH. Dopaminergic abnormalities in select thalamic nuclei in schizophrenia: involvement of the intracellular signal integrating proteins calcyon and spinophilin. The American Journal of Psychiatry. 162: 1859-71. PMID 16199832 DOI: 10.1176/Appi.Ajp.162.10.1859 |
0.399 |
|
| 2005 |
Zhao Z, Ho L, Wang J, Qin W, Festa ED, Mobbs C, Hof P, Rocher A, Masur S, Haroutunian V, Pasinetti GM. Connective tissue growth factor (CTGF) expression in the brain is a downstream effector of insulin resistance- associated promotion of Alzheimer's disease beta-amyloid neuropathology. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 2081-2. PMID 16186174 DOI: 10.1096/Fj.05-4359Fje |
0.339 |
|
| 2005 |
Katsel P, Davis KL, Haroutunian V. Variations in myelin and oligodendrocyte-related gene expression across multiple brain regions in schizophrenia: a gene ontology study. Schizophrenia Research. 79: 157-73. PMID 16139990 DOI: 10.1016/J.Schres.2005.06.007 |
0.397 |
|
| 2005 |
Gupta DS, McCullumsmith RE, Beneyto M, Haroutunian V, Davis KL, Meador-Woodruff JH. Metabotropic glutamate receptor protein expression in the prefrontal cortex and striatum in schizophrenia. Synapse (New York, N.Y.). 57: 123-31. PMID 15945063 DOI: 10.1002/Syn.20164 |
0.427 |
|
| 2005 |
Katsel P, Davis KL, Gorman JM, Haroutunian V. Variations in differential gene expression patterns across multiple brain regions in schizophrenia. Schizophrenia Research. 77: 241-52. PMID 15923110 DOI: 10.1016/J.Schres.2005.03.020 |
0.416 |
|
| 2005 |
Bubber P, Haroutunian V, Fisch G, Blass JP, Gibson GE. Mitochondrial abnormalities in Alzheimer brain: mechanistic implications. Annals of Neurology. 57: 695-703. PMID 15852400 DOI: 10.1002/Ana.20474 |
0.308 |
|
| 2005 |
Bruneau EG, McCullumsmith RE, Haroutunian V, Davis KL, Meador-Woodruff JH. Increased expression of glutaminase and glutamine synthetase mRNA in the thalamus in schizophrenia. Schizophrenia Research. 75: 27-34. PMID 15820321 DOI: 10.1016/J.Schres.2004.12.012 |
0.411 |
|
| 2005 |
Katsel PL, Davis KL, Haroutunian V. Large-scale microarray studies of gene expression in multiple regions of the brain in schizophrenia and Alzheimer's disease. International Review of Neurobiology. 63: 41-82. PMID 15797465 DOI: 10.1016/S0074-7742(05)63003-6 |
0.398 |
|
| 2005 |
Dracheva S, McGurk SR, Haroutunian V. mRNA expression of AMPA receptors and AMPA receptor binding proteins in the cerebral cortex of elderly schizophrenics. Journal of Neuroscience Research. 79: 868-78. PMID 15696539 DOI: 10.1002/Jnr.20423 |
0.675 |
|
| 2004 |
Buckland PR, Hoogendoorn B, Guy CA, Coleman SL, Smith SK, Buxbaum JD, Haroutunian V, O'Donovan MC. A high proportion of polymorphisms in the promoters of brain expressed genes influences transcriptional activity. Biochimica Et Biophysica Acta. 1690: 238-49. PMID 15511631 DOI: 10.1016/J.Bbadis.2004.06.023 |
0.341 |
|
| 2004 |
Cataldo AM, Petanceska S, Terio NB, Peterhoff CM, Durham R, Mercken M, Mehta PD, Buxbaum J, Haroutunian V, Nixon RA. Abeta localization in abnormal endosomes: association with earliest Abeta elevations in AD and Down syndrome. Neurobiology of Aging. 25: 1263-72. PMID 15465622 DOI: 10.1016/J.Neurobiolaging.2004.02.027 |
0.31 |
|
| 2004 |
Bubber P, Tang J, Haroutunian V, Xu H, Davis KL, Blass JP, Gibson GE. Mitochondrial enzymes in schizophrenia. Journal of Molecular Neuroscience : Mn. 24: 315-21. PMID 15456945 DOI: 10.1385/Jmn:24:2:315 |
0.359 |
|
| 2004 |
Brown AM, Gordon D, Lee H, Caudy M, Hardy J, Haroutunian V, Blass JP. Association of the dihydrolipoamide dehydrogenase gene with Alzheimer's disease in an Ashkenazi Jewish population. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 131: 60-6. PMID 15389771 DOI: 10.1002/Ajmg.B.30008 |
0.324 |
|
| 2004 |
Bray NJ, Jehu L, Moskvina V, Buxbaum JD, Dracheva S, Haroutunian V, Williams J, Buckland PR, Owen MJ, O'Donovan MC. Allelic expression of APOE in human brain: effects of epsilon status and promoter haplotypes. Human Molecular Genetics. 13: 2885-92. PMID 15385439 DOI: 10.1093/Hmg/Ddh299 |
0.647 |
|
| 2004 |
Bai J, He F, Novikova SI, Undie AS, Dracheva S, Haroutunian V, Lidow MS. Abnormalities in the dopamine system in schizophrenia may lie in altered levels of dopamine receptor-interacting proteins. Biological Psychiatry. 56: 427-40. PMID 15364041 DOI: 10.1016/J.Biopsych.2004.06.022 |
0.693 |
|
| 2004 |
Dracheva S, Elhakem SL, McGurk SR, Davis KL, Haroutunian V. GAD67 and GAD65 mRNA and protein expression in cerebrocortical regions of elderly patients with schizophrenia. Journal of Neuroscience Research. 76: 581-92. PMID 15114630 DOI: 10.1002/Jnr.20122 |
0.687 |
|
| 2004 |
Mueller HT, Haroutunian V, Davis KL, Meador-Woodruff JH. Expression of the ionotropic glutamate receptor subunits and NMDA receptor-associated intracellular proteins in the substantia nigra in schizophrenia. Brain Research. Molecular Brain Research. 121: 60-9. PMID 14969737 DOI: 10.1016/J.Molbrainres.2003.11.004 |
0.389 |
|
| 2004 |
Clinton SM, Abelson S, Haroutunian V, Davis K, Meador-Woodruff JH. Neurofilament subunit protein abnormalities in the thalamus in schizophrenia Thalamus and Related Systems. 2: 265-272. DOI: 10.1016/J.Tharel.2003.11.001 |
0.353 |
|
| 2003 |
Dracheva S, Elhakem SL, Marcus SM, Siever LJ, McGurk SR, Haroutunian V. RNA editing and alternative splicing of human serotonin 2C receptor in schizophrenia. Journal of Neurochemistry. 87: 1402-12. PMID 14713296 DOI: 10.1046/J.1471-4159.2003.02115.X |
0.685 |
|
| 2003 |
Martin-Ruiz CM, Haroutunian VH, Long P, Young AH, Davis KL, Perry EK, Court JA. Dementia rating and nicotinic receptor expression in the prefrontal cortex in schizophrenia. Biological Psychiatry. 54: 1222-33. PMID 14643090 DOI: 10.1016/S0006-3223(03)00348-2 |
0.306 |
|
| 2003 |
Halks-Miller M, Schroeder ML, Haroutunian V, Moenning U, Rossi M, Achim C, Purohit D, Mahmoudi M, Horuk R. CCR1 is an early and specific marker of Alzheimer's disease. Annals of Neurology. 54: 638-46. PMID 14595653 DOI: 10.1002/Ana.10733 |
0.352 |
|
| 2003 |
Causevic M, Ramoz N, Haroutunian V, Davis KL, Buxbaum JD. Lack of association between the levels of the low-density lipoprotein receptor-related protein (LRP) and either Alzheimer dementia or LRP exon 3 genotype. Journal of Neuropathology and Experimental Neurology. 62: 999-1005. PMID 14575236 DOI: 10.1093/Jnen/62.10.999 |
0.367 |
|
| 2003 |
Davis KL, Haroutunian V. Global expression-profiling studies and oligodendrocyte dysfunction in schizophrenia and bipolar disorder. Lancet. 362: 758. PMID 13678867 DOI: 10.1016/S0140-6736(03)14297-3 |
0.357 |
|
| 2003 |
Polesskaya OO, Haroutunian V, Davis KL, Hernandez I, Sokolov BP. Novel putative nonprotein-coding RNA gene from 11q14 displays decreased expression in brains of patients with schizophrenia. Journal of Neuroscience Research. 74: 111-22. PMID 13130513 DOI: 10.1002/Jnr.10752 |
0.408 |
|
| 2003 |
Hof PR, Haroutunian V, Friedrich VL, Byne W, Buitron C, Perl DP, Davis KL. Loss and altered spatial distribution of oligodendrocytes in the superior frontal gyrus in schizophrenia. Biological Psychiatry. 53: 1075-85. PMID 12814859 DOI: 10.1016/S0006-3223(03)00237-3 |
0.369 |
|
| 2003 |
Clinton SM, Haroutunian V, Davis KL, Meador-Woodruff JH. Altered transcript expression of NMDA receptor-associated postsynaptic proteins in the thalamus of subjects with schizophrenia. The American Journal of Psychiatry. 160: 1100-9. PMID 12777268 DOI: 10.1176/Appi.Ajp.160.6.1100 |
0.374 |
|
| 2003 |
Davis KL, Stewart DG, Friedman JI, Buchsbaum M, Harvey PD, Hof PR, Buxbaum J, Haroutunian V. White matter changes in schizophrenia: evidence for myelin-related dysfunction. Archives of General Psychiatry. 60: 443-56. PMID 12742865 DOI: 10.1001/Archpsyc.60.5.443 |
0.366 |
|
| 2003 |
Religa D, Laudon H, Styczynska M, Winblad B, Näslund J, Haroutunian V. Amyloid beta pathology in Alzheimer's disease and schizophrenia. The American Journal of Psychiatry. 160: 867-72. PMID 12727689 DOI: 10.1176/Appi.Ajp.160.5.867 |
0.372 |
|
| 2003 |
Serby M, Brickman AM, Haroutunian V, Purohit DP, Marin D, Lantz M, Mohs RC, Davis KL. Cognitive burden and excess Lewy-body pathology in the Lewy-body variant of Alzheimer disease. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 11: 371-4. PMID 12724118 DOI: 10.1097/00019442-200305000-00016 |
0.301 |
|
| 2003 |
Haroutunian V, Dracheva S, Davis KL. Neurobiology of glutamatergic abnormalities in schizophrenia Clinical Neuroscience Research. 3: 67-76. DOI: 10.1016/S1566-2772(03)00020-3 |
0.681 |
|
| 2003 |
Davis K, Stewart D, Friedman J, Buchsbaum M, Harvey P, Hof P, Buxbaum J, Haroutunian V. S.18.01 Schizophrenia: Effects of aging on cognition European Neuropsychopharmacology. 13. DOI: 10.1016/S0924-977X(03)91669-5 |
0.339 |
|
| 2002 |
Hof PR, Haroutunian V, Copland C, Davis KL, Buxbaum JD. Molecular and cellular evidence for an oligodendrocyte abnormality in schizophrenia. Neurochemical Research. 27: 1193-200. PMID 12462417 DOI: 10.1023/A:1020981510759 |
0.411 |
|
| 2002 |
Gluck MR, Thomas RG, Davis KL, Haroutunian V. Implications for altered glutamate and GABA metabolism in the dorsolateral prefrontal cortex of aged schizophrenic patients. The American Journal of Psychiatry. 159: 1165-73. PMID 12091195 DOI: 10.1176/Appi.Ajp.159.7.1165 |
0.336 |
|
| 2002 |
Byne W, Buchsbaum MS, Mattiace LA, Hazlett EA, Kemether E, Elhakem SL, Purohit DP, Haroutunian V, Jones L. Postmortem assessment of thalamic nuclear volumes in subjects with schizophrenia. The American Journal of Psychiatry. 159: 59-65. PMID 11772691 DOI: 10.1176/Appi.Ajp.159.1.59 |
0.335 |
|
| 2001 |
Parvathy S, Davies P, Haroutunian V, Purohit DP, Davis KL, Mohs RC, Park H, Moran TM, Chan JY, Buxbaum JD. Correlation between Abetax-40-, Abetax-42-, and Abetax-43-containing amyloid plaques and cognitive decline. Archives of Neurology. 58: 2025-32. PMID 11735776 DOI: 10.1001/Archneur.58.12.2025 |
0.302 |
|
| 2001 |
Smith RE, Haroutunian V, Davis KL, Meador-Woodruff JH. Vesicular glutamate transporter transcript expression in the thalamus in schizophrenia. Neuroreport. 12: 2885-7. PMID 11588596 DOI: 10.1097/00001756-200109170-00026 |
0.41 |
|
| 2001 |
Dracheva S, Marras SA, Elhakem SL, Kramer FR, Davis KL, Haroutunian V. N-methyl-D-aspartic acid receptor expression in the dorsolateral prefrontal cortex of elderly patients with schizophrenia. The American Journal of Psychiatry. 158: 1400-10. PMID 11532724 DOI: 10.1176/Appi.Ajp.158.9.1400 |
0.689 |
|
| 2001 |
Smith RE, Haroutunian V, Davis KL, Meador-Woodruff JH. Expression of excitatory amino acid transporter transcripts in the thalamus of subjects with schizophrenia. The American Journal of Psychiatry. 158: 1393-9. PMID 11532723 DOI: 10.1176/Appi.Ajp.158.9.1393 |
0.409 |
|
| 2001 |
Dracheva S, Haroutunian V. Locomotor behavior of dopamine D1 receptor transgenic/D2 receptor deficient hybrid mice. Brain Research. 905: 142-51. PMID 11423089 DOI: 10.1016/S0006-8993(01)02522-7 |
0.62 |
|
| 2001 |
Brown AM, Sheu RK, Mohs R, Haroutunian V, Blass JP. Correlation of the clinical severity of Alzheimer's disease with an aberration in mitochondrial DNA (mtDNA). Journal of Molecular Neuroscience : Mn. 16: 41-8. PMID 11345519 DOI: 10.1385/Jmn:16:1:41 |
0.32 |
|
| 2001 |
Hakak Y, Walker JR, Li C, Wong WH, Davis KL, Buxbaum JD, Haroutunian V, Fienberg AA. Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 98: 4746-51. PMID 11296301 DOI: 10.1073/Pnas.081071198 |
0.429 |
|
| 2001 |
Meador-Woodruff JH, Davis KL, Haroutunian V. Abnormal kainate receptor expression in prefrontal cortex in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 24: 545-52. PMID 11282254 DOI: 10.1016/S0893-133X(00)00189-5 |
0.422 |
|
| 2001 |
Ho L, Purohit D, Haroutunian V, Luterman JD, Willis F, Naslund J, Buxbaum JD, Mohs RC, Aisen PS, Pasinetti GM. Neuronal cyclooxygenase 2 expression in the hippocampal formation as a function of the clinical progression of Alzheimer disease. Archives of Neurology. 58: 487-92. PMID 11255454 DOI: 10.1001/Archneur.58.3.487 |
0.344 |
|
| 2000 |
Ibrahim HM, Hogg AJ, Healy DJ, Haroutunian V, Davis KL, Meador-Woodruff JH. Ionotropic glutamate receptor binding and subunit mRNA expression in thalamic nuclei in schizophrenia. The American Journal of Psychiatry. 157: 1811-23. PMID 11058479 DOI: 10.1176/Appi.Ajp.157.11.1811 |
0.394 |
|
| 2000 |
Gibson GE, Haroutunian V, Zhang H, Park LC, Shi Q, Lesser M, Mohs RC, Sheu RK, Blass JP. Mitochondrial damage in Alzheimer's disease varies with apolipoprotein E genotype. Annals of Neurology. 48: 297-303. PMID 10976635 DOI: 10.1002/1531-8249(200009)48:3<297::Aid-Ana3>3.0.Co;2-Z |
0.326 |
|
| 2000 |
Luterman JD, Haroutunian V, Yemul S, Ho L, Purohit D, Aisen PS, Mohs R, Pasinetti GM. Cytokine gene expression as a function of the clinical progression of Alzheimer disease dementia. Archives of Neurology. 57: 1153-60. PMID 10927795 DOI: 10.1001/Archneur.57.8.1153 |
0.37 |
|
| 2000 |
Haroutunian V, Serby M, Purohit DP, Perl DP, Marin D, Lantz M, Mohs RC, Davis KL. Contribution of Lewy body inclusions to dementia in patients with and without Alzheimer disease neuropathological conditions. Archives of Neurology. 57: 1145-50. PMID 10927794 DOI: 10.1001/Archneur.57.8.1145 |
0.331 |
|
| 2000 |
Perry E, Martin-Ruiz C, Lee M, Griffiths M, Johnson M, Piggott M, Haroutunian V, Buxbaum JD, Nãsland J, Davis K, Gotti C, Clementi F, Tzartos S, Cohen O, Soreq H, et al. Nicotinic receptor subtypes in human brain ageing, Alzheimer and Lewy body diseases. European Journal of Pharmacology. 393: 215-22. PMID 10771016 DOI: 10.1016/S0014-2999(00)00064-9 |
0.316 |
|
| 2000 |
Näslund J, Haroutunian V, Mohs R, Davis KL, Davies P, Greengard P, Buxbaum JD. Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline. Jama. 283: 1571-7. PMID 10735393 DOI: 10.1001/Jama.283.12.1571 |
0.301 |
|
| 2000 |
Richardson-Burns SM, Haroutunian V, Davis KL, Watson SJ, Meador-Woodruff JH. Metabotropic glutamate receptor mRNA expression in the schizophrenic thalamus. Biological Psychiatry. 47: 22-8. PMID 10650445 DOI: 10.1016/S0006-3223(99)00207-3 |
0.418 |
|
| 2000 |
Dracheva S, Haroutunian V, Grandy D, Sealfon S. 230. Characterization of the dopamine D1 receptor transgenic mice Biological Psychiatry. 47: S70. DOI: 10.1016/S0006-3223(00)00494-7 |
0.576 |
|
| 2000 |
Meador-Woodruff J, Desmond T, Frey K, Haroutunian V, Davis K, Watson S. 158. Decreased vesicular monoamine transporter density in schizophrenic prefrontal cortex Biological Psychiatry. 47: S48. DOI: 10.1016/S0006-3223(00)00420-0 |
0.373 |
|
| 2000 |
Clinton S, Healy D, Smith R, Haroutunian V, Davis K, Watson S, Meador-Woodruff J. 157. Expression of exon 22-containing NR1 NMDA receptor subunits in thalamus in schizophrenia Biological Psychiatry. 47: S47. DOI: 10.1016/S0006-3223(00)00419-4 |
0.377 |
|
| 1999 |
Davis KL, Mohs RC, Marin DB, Purohit DP, Perl DP, Lantz M, Austin G, Haroutunian V. Neuropeptide abnormalities in patients with early Alzheimer disease. Archives of General Psychiatry. 56: 981-7. PMID 10565496 DOI: 10.1001/Archpsyc.56.11.981 |
0.331 |
|
| 1999 |
Haroutunian V, Purohit DP, Perl DP, Marin D, Khan K, Lantz M, Davis KL, Mohs RC. Neurofibrillary tangles in nondemented elderly subjects and mild Alzheimer disease. Archives of Neurology. 56: 713-8. PMID 10369312 DOI: 10.1001/Archneur.56.6.713 |
0.346 |
|
| 1999 |
Dracheva S, Xu M, Kelley KA, Haroutunian V, Holstein GR, Haun S, Silverstein JH, Sealfon SC. Paradoxical locomotor behavior of dopamine D1 receptor transgenic mice. Experimental Neurology. 157: 169-79. PMID 10222120 DOI: 10.1006/Exnr.1999.7037 |
0.629 |
|
| 1999 |
Davis KL, Mohs RC, Marin D, Purohit DP, Perl DP, Lantz M, Austin G, Haroutunian V. Cholinergic markers in elderly patients with early signs of Alzheimer disease. Jama. 281: 1401-6. PMID 10217056 DOI: 10.1001/Jama.281.15.1401 |
0.35 |
|
| 1999 |
Kaplan B, Haroutunian V, Koudinov A, Patael Y, Pras M, Gallo G. Biochemical assay for amyloid beta deposits to distinguish Alzheimer's disease from other dementias. Clinica Chimica Acta; International Journal of Clinical Chemistry. 280: 147-59. PMID 10090532 DOI: 10.1016/S0009-8981(98)00190-9 |
0.32 |
|
| 1999 |
Sheu KF, Brown AM, Haroutunian V, Kristal BS, Thaler H, Lesser M, Kalaria RN, Relkin NR, Mohs RC, Lilius L, Lannfelt L, Blass JP. Modulation by DLST of the genetic risk of Alzheimer's disease in a very elderly population. Annals of Neurology. 45: 48-53. PMID 9894876 DOI: 10.1002/1531-8249(199901)45:1<48::Aid-Art9>3.0.Co;2-V |
0.319 |
|
| 1998 |
Haroutunian V, Perl DP, Purohit DP, Marin D, Khan K, Lantz M, Davis KL, Mohs RC. Regional distribution of neuritic plaques in the nondemented elderly and subjects with very mild Alzheimer disease. Archives of Neurology. 55: 1185-91. PMID 9740112 DOI: 10.1001/Archneur.55.9.1185 |
0.32 |
|
| 1998 |
Powchik P, Davidson M, Haroutunian V, Gabriel SM, Purohit DP, Perl DP, Harvey PD, Davis KL. Postmortem studies in schizophrenia. Schizophrenia Bulletin. 24: 325-41. PMID 9718627 DOI: 10.1093/Oxfordjournals.Schbul.A033330 |
0.407 |
|
| 1998 |
Healy DJ, Haroutunian V, Powchik P, Davidson M, Davis KL, Watson SJ, Meador-Woodruff JH. AMPA receptor binding and subunit mRNA expression in prefrontal cortex and striatum of elderly schizophrenics. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 19: 278-86. PMID 9718591 DOI: 10.1016/S0893-133X(98)00014-1 |
0.413 |
|
| 1998 |
Reznik-Wolf H, Machado J, Haroutunian V, DeMarco L, Walter GF, Goldman B, Davidson M, Johnston JA, Lannfelt L, Dani SU, Friedman E. Somatic mutation analysis of the APP and Presenilin 1 and 2 genes in Alzheimer's disease brains. Journal of Neurogenetics. 12: 55-65. PMID 9666901 DOI: 10.3109/01677069809108555 |
0.307 |
|
| 1998 |
Purohit DP, Perl DP, Haroutunian V, Powchik P, Davidson M, Davis KL. Alzheimer disease and related neurodegenerative diseases in elderly patients with schizophrenia: a postmortem neuropathologic study of 100 cases. Archives of General Psychiatry. 55: 205-11. PMID 9510214 DOI: 10.1001/Archpsyc.55.3.205 |
0.401 |
|
| 1998 |
Sokolov B, Tcherepanov A, Haroutunian V, Davis K. 30. Decreased levels of NMDAR1, GLUR1, GLUR7 and KA1 MRNAS in frontal cortex of schizophrenics Biological Psychiatry. 43: S10. DOI: 10.1016/S0006-3223(98)90478-4 |
0.319 |
|
| 1997 |
Meador-Woodruff JH, Haroutunian V, Powchik P, Davidson M, Davis KL, Watson SJ. Dopamine receptor transcript expression in striatum and prefrontal and occipital cortex. Focal abnormalities in orbitofrontal cortex in schizophrenia. Archives of General Psychiatry. 54: 1089-95. PMID 9400344 DOI: 10.1001/Archpsyc.1997.01830240045007 |
0.395 |
|
| 1997 |
Powchik P, Friedman J, Haroutunian V, Greenberg D, Altsteil L, Purohit D, Perl D, Davidson M. Apolipoprotein E4 in schizophrenia: a study of one hundred sixteen cases with concomitant neuropathological examination. Biological Psychiatry. 42: 296-8. PMID 9270908 DOI: 10.1016/S0006-3223(97)00034-6 |
0.343 |
|
| 1997 |
Gabriel SM, Haroutunian V, Powchik P, Honer WG, Davidson M, Davies P, Davis KL. Increased concentrations of presynaptic proteins in the cingulate cortex of subjects with schizophrenia. Archives of General Psychiatry. 54: 559-66. PMID 9193197 DOI: 10.1001/Archpsyc.1997.01830180077010 |
0.411 |
|
| 1997 |
Meador-Woodruff JH, Healy DJ, Damask SP, Haroutunian V, Powchik P, Davidson M, Davis KL, Watson SJ. Ionotropic glutamate receptor mRNA expression in schizophrenia Schizophrenia Research. 24: 87-88. DOI: 10.1016/S0920-9964(97)82237-2 |
0.394 |
|
| 1996 |
Meador-Woodruff JH, Damask SP, Wang J, Haroutunian V, Davis KL, Watson SJ. Dopamine receptor mRNA expression in human striatum and neocortex. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 15: 17-29. PMID 8797188 DOI: 10.1016/0893-133X(95)00150-C |
0.326 |
|
| 1996 |
Li G, Silverman JM, Altstiel LD, Haroutunian V, Perl DP, Purohit D, Birstein S, Lantz M, Mohs RC, Davis KL. Apolipoprotein E-epsilon 4 allele and familial risk in Alzheimer's disease. Genetic Epidemiology. 13: 285-98. PMID 8797010 DOI: 10.1002/(Sici)1098-2272(1996)13:3<285::Aid-Gepi5>3.0.Co;2-5 |
0.321 |
|
| 1996 |
Gabriel SM, Davidson M, Haroutunian V, Powchik P, Bierer LM, Purohit DP, Perl DP, Davis KL. Neuropeptide deficits in schizophrenia vs. Alzheimer's disease cerebral cortex. Biological Psychiatry. 39: 82-91. PMID 8717605 DOI: 10.1016/0006-3223(95)00066-6 |
0.415 |
|
| 1996 |
Meador-Woodruff J, Damask S, Haroutunian V, Davidson M, Powchik P, Davis K, Watson S. Dopamine receptor transcript expression in schizophrenia European Neuropsychopharmacology. 6: 92. DOI: 10.1016/0924-977X(96)87723-6 |
0.377 |
|
| 1995 |
Bierer LM, Haroutunian V, Gabriel S, Knott PJ, Carlin LS, Purohit DP, Perl DP, Schmeidler J, Kanof P, Davis KL. Neurochemical correlates of dementia severity in Alzheimer's disease: relative importance of the cholinergic deficits. Journal of Neurochemistry. 64: 749-60. PMID 7830069 DOI: 10.1046/J.1471-4159.1995.64020749.X |
0.328 |
|
| 1995 |
Wallace WC, Lieberburg I, Schenk D, Vigo-Pelfrey C, Davis KL, Haroutunian V. Chronic elevation of secreted amyloid precursor protein in subcortically lesioned rats, and its exacerbation in aged rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 4896-905. PMID 7623120 DOI: 10.1523/Jneurosci.15-07-04896.1995 |
0.31 |
|
| 1995 |
Lawlor BA, Ryan TM, Bierer LM, Schmeidler J, Haroutunian V, Mohs R, Davis KL. Lack of association between clinical symptoms and postmortem indices of brain serotonin function in Alzheimer's disease. Biological Psychiatry. 37: 895-6. PMID 7548465 DOI: 10.1016/0006-3223(95)00035-F |
0.324 |
|
| 1995 |
Powchik P, Davidson M, Gabriel SM, Haroutunian V, Harvey PD, Davis KL. Somatostatin and NPY deficits in schizophrenic cortex Schizophrenia Research. 15: 26-27. DOI: 10.1016/0920-9964(95)95093-O |
0.308 |
|
| 1994 |
Haroutunian V, Davidson M, Kanof PD, Perl DP, Powchik P, Losonczy M, McCrystal J, Purohit DP, Bierer LM, Davis KL. Cortical cholinergic markers in schizophrenia. Schizophrenia Research. 12: 137-44. PMID 8043524 DOI: 10.1016/0920-9964(94)90071-X |
0.387 |
|
| 1993 |
Schmauss C, Haroutunian V, Davis KL, Davidson M. Selective loss of dopamine D3-type receptor mRNA expression in parietal and motor cortices of patients with chronic schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 90: 8942-6. PMID 8415635 DOI: 10.1073/Pnas.90.19.8942 |
0.38 |
|
| 1993 |
Powchik P, Davidson M, Nemeroff CB, Haroutunian V, Purohit D, Losonczy M, Bissette G, Perl D, Ghanbari H, Miller B. Alzheimer's-disease-related protein in geriatric schizophrenic patients with cognitive impairment. The American Journal of Psychiatry. 150: 1726-7. PMID 8214183 DOI: 10.1176/Ajp.150.11.1726 |
0.326 |
|
| 1993 |
Bierer LM, Knott PJ, Schmeidler JM, Marin DB, Ryan TM, Haroutunian V, Purohit DP, Perl DP, Mohs RC, Davis KL. Post-mortem examination of dopaminergic parameters in Alzheimer's disease: relationship to noncognitive symptoms. Psychiatry Research. 49: 211-7. PMID 8177917 DOI: 10.1016/0165-1781(93)90062-L |
0.322 |
|
| 1993 |
Wallace W, Haroutunian V. Using the subcortically lesioned rat cortex to understand the physiological role of amyloid precursor protein. Behavioural Brain Research. 57: 199-206. PMID 8117425 DOI: 10.1016/0166-4328(93)90136-E |
0.364 |
|
| 1992 |
Johnson G, Gotlib J, Haroutunian V, Bierer L, Nairn AC, Merril C, Wallace W. Increased phosphorylation of elongation factor 2 in Alzheimer's disease. Brain Research. Molecular Brain Research. 15: 319-26. PMID 1331687 DOI: 10.1016/0169-328X(92)90124-T |
0.348 |
|
| 1991 |
Perez N, Sugar J, Charya S, Johnson G, Merril C, Bierer L, Perl D, Haroutunian V, Wallace W. Increased synthesis and accumulation of heat shock 70 proteins in Alzheimer's disease. Brain Research. Molecular Brain Research. 11: 249-54. PMID 1661822 DOI: 10.1016/0169-328X(91)90033-T |
0.318 |
|
| 1991 |
Wallace WC, Bragin V, Robakis NK, Sambamurti K, VanderPutten D, Merril CR, Davis KL, Santucci AC, Haroutunian V. Increased biosynthesis of Alzheimer amyloid precursor protein in the cerebral cortex of rats with lesions of the nucleus basalis of Meynert. Brain Research. Molecular Brain Research. 10: 173-8. PMID 1649369 DOI: 10.1016/0169-328X(91)90108-A |
0.336 |
|
| 1990 |
Haroutunian V, Santucci AC, Davis KL. Implications of multiple transmitter system lesions for cholinomimetic therapy in Alzheimer's disease. Progress in Brain Research. 84: 333-46. PMID 1980019 DOI: 10.1016/S0079-6123(08)60917-6 |
0.312 |
|
| 1989 |
Santucci AC, Kanof PD, Haroutunian V. Infusion of NMDA into the nucleus basalis of Meynert, frontal cortex or lateral ventricle in rats: effect on memory and cholinergic brain neurochemistry. Pharmacology, Biochemistry, and Behavior. 33: 485-8. PMID 2682674 DOI: 10.1016/0091-3057(89)90535-2 |
0.306 |
|
| 1989 |
Anderson J, Wallace W, Snyder S, Haroutunian V, Roberts JL, Lieberburg I. Cellular forms of the rat and human beta-amyloid precursor protein (BAPP). Brain Research. 478: 391-8. PMID 2647209 DOI: 10.1016/0006-8993(89)91523-0 |
0.3 |
|
| 1989 |
Anderson JP, Refolo LM, Wallace W, Mehta P, Krishnamurthi M, Gotlib J, Bierer L, Haroutunian V, Perl D, Robakis NK. Differential brain expression of the Alzheimer's amyloid precursor protein. The Embo Journal. 8: 3627-32. PMID 2583112 DOI: 10.1002/J.1460-2075.1989.Tb08536.X |
0.348 |
|
| 1989 |
Charya S, Parks KM, Merril C, Bierer L, Perl D, Haroutunian V, Davis KL, Wallace W. Examination of proteins whose synthesis is Altered in Alzheimer's disease Biological Psychiatry. 25. DOI: 10.1016/0006-3223(89)91722-8 |
0.304 |
|
| 1989 |
Knott P, Haroutunian V, Bierer L, Perl D, Handler M, DeLeon M, Yang R, Davis K. Correlations post-mortem between ventricular CSF and cortical tissue concentrations of MHPG, 5-HIAA and HVA in Alzheimer's disease Biological Psychiatry. 25. DOI: 10.1016/0006-3223(89)91712-5 |
0.332 |
|
| 1986 |
Haroutunian V, Kanof PD, Tsuboyama GK, Campbell GA, Davis KL. Animal models of Alzheimer's disease: behavior, pharmacology, transplants. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 13: 385-93. PMID 2878711 DOI: 10.1017/S0317167100036957 |
0.305 |
|
| 1985 |
Johns CA, Haroutunian V, Greenwald BS, Mohs RC, Davis BM, Kanof P, Horvath TB, Davis MDKL. Development of cholinergic drugs for the treatment of Alzheimer's disease Drug Development Research. 5: 77-96. DOI: 10.1002/Ddr.430050108 |
0.329 |
|
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