Vahram Haroutunian, Ph.D. - Publications

Affiliations: 
Psychiatry Mount Sinai School of Medicine / Bronx VA Hospital 
Area:
neurobiology of Alzheimer's disease and schizophrenia,

415 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Yang Y, Tapias V, Acosta D, Xu H, Chen H, Bhawal R, Anderson ET, Ivanova E, Lin H, Sagdullaev BT, Chen J, Klein WL, Viola KL, Gandy S, Haroutunian V, et al. Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer's disease. Nature Communications. 13: 159. PMID 35013160 DOI: 10.1038/s41467-021-27572-2  1
2021 Peng S, Zeng L, Haure-Mirande JV, Wang M, Huffman DM, Haroutunian V, Ehrlich ME, Zhang B, Tu Z. Transcriptomic Changes Highly Similar to Alzheimer's Disease Are Observed in a Subpopulation of Individuals During Normal Brain Aging. Frontiers in Aging Neuroscience. 13: 711524. PMID 34924992 DOI: 10.3389/fnagi.2021.711524  1
2021 Ming C, Wang M, Wang Q, Neff R, Wang E, Shen Q, Reddy JS, Wang X, Allen M, Ertekin-Taner N, De Jager PL, Bennett DA, Haroutunian V, Schadt E, Zhang B. Whole genome sequencing-based copy number variations reveal novel pathways and targets in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 34918867 DOI: 10.1002/alz.12507  1
2021 Cao J, Huang M, Guo L, Zhu L, Hou J, Zhang L, Pero A, Ng S, Gaamouch FE, Elder G, Sano M, Goate A, Tcw J, Haroutunian V, Zhang B, et al. MicroRNA-195 rescues AD-associated lysosomal defects. Molecular Psychiatry. 26: 4563. PMID 34773105 DOI: 10.1038/s41380-021-01286-9  1
2021 Katsel P, Fam P, Tan W, Khan S, Gama-Sosa M, De Gasperi R, Roussos P, Robinson A, Cooper I, Schnaider-Beeri M, Haroutunian V. Engagement of vascular early response genes typifies mild cognitive impairment. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 34758195 DOI: 10.1002/alz.12481  1
2021 Roberts JA, Varma VR, An Y, Varma S, Candia J, Fantoni G, Tiwari V, Anerillas C, Williamson A, Saito A, Loeffler T, Schilcher I, Moaddel R, Khadeer M, Lovett J, ... ... Haroutunian V, et al. A brain proteomic signature of incipient Alzheimer's disease in young ε4 carriers identifies novel drug targets. Science Advances. 7: eabi8178. PMID 34757788 DOI: 10.1126/sciadv.abi8178  1
2021 Farrell K, Kim S, Han N, Iida MA, Gonzalez EM, Otero-Garcia M, Walker JM, Richardson TE, Renton AE, Andrews SJ, Fulton-Howard B, Humphrey J, Vialle RA, Bowles KR, de Paiva Lopes K, ... ... Haroutunian V, et al. Genome-wide association study and functional validation implicates JADE1 in tauopathy. Acta Neuropathologica. PMID 34719765 DOI: 10.1007/s00401-021-02379-z  1
2021 Iida MA, Farrell K, Walker JM, Richardson TE, Marx GA, Bryce CH, Purohit D, Ayalon G, Beach TG, Bigio EH, Cortes EP, Gearing M, Haroutunian V, McMillan CT, Lee EB, et al. Predictors of cognitive impairment in primary age-related tauopathy: an autopsy study. Acta Neuropathologica Communications. 9: 134. PMID 34353357 DOI: 10.1186/s40478-021-01233-3  1
2021 Wu X, Shukla R, Alganem K, Zhang X, Eby HM, Devine EA, Depasquale E, Reigle J, Simmons M, Hahn MK, Au-Yeung C, Asgariroozbehani R, Hahn CG, Haroutunian V, Meller J, et al. Transcriptional profile of pyramidal neurons in chronic schizophrenia reveals lamina-specific dysfunction of neuronal immunity. Molecular Psychiatry. PMID 34272489 DOI: 10.1038/s41380-021-01205-y  1
2021 Hertzberg L, Maggio N, Muler I, Yitzhaky A, Majer M, Haroutunian V, Zuk O, Katsel P, Domany E, Weiser M. Erratum to: Comprehensive Gene Expression Analysis Detects Global Reduction of Proteasome Subunits in Schizophrenia. Schizophrenia Bulletin. PMID 34165562 DOI: 10.1093/schbul/sbab073  1
2021 Smith RG, Pishva E, Shireby G, Smith AR, Roubroeks JAY, Hannon E, Wheildon G, Mastroeni D, Gasparoni G, Riemenschneider M, Giese A, Sharp AJ, Schalkwyk L, Haroutunian V, Viechtbauer W, et al. A meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex. Nature Communications. 12: 3517. PMID 34112773 DOI: 10.1038/s41467-021-23243-4  1
2021 Bargar C, Wang W, Gunzler SA, LeFevre A, Wang Z, Lerner AJ, Singh N, Tatsuoka C, Appleby B, Zhu X, Xu R, Haroutunian V, Zou WQ, Ma J, Chen SG. Streamlined alpha-synuclein RT-QuIC assay for various biospecimens in Parkinson's disease and dementia with Lewy bodies. Acta Neuropathologica Communications. 9: 62. PMID 33827706 DOI: 10.1186/s40478-021-01175-w  0.01
2021 Patel A, Sul J, Gordon ML, Steinklein J, Sanguinetti S, Pramanik B, Purohit D, Haroutunian V, Williamson A, Koralnik I, Harel A. Progressive Multifocal Leukoencephalopathy in a Patient With Progressive Multiple Sclerosis Treated With Ocrelizumab Monotherapy. Jama Neurology. PMID 33724354 DOI: 10.1001/jamaneurol.2021.0627  1
2021 Yu K, Niu M, Wang H, Li Y, Wu Z, Zhang B, Haroutunian V, Peng J. Global Profiling of Lysine Accessibility to Evaluate Protein Structure Changes in Alzheimer's Disease. Journal of the American Society For Mass Spectrometry. PMID 33683887 DOI: 10.1021/jasms.0c00450  1
2021 Neff RA, Wang M, Vatansever S, Guo L, Ming C, Wang Q, Wang E, Horgusluoglu-Moloch E, Song WM, Li A, Castranio EL, Tcw J, Ho L, Goate A, Fossati V, ... ... Haroutunian V, et al. Molecular subtyping of Alzheimer's disease using RNA sequencing data reveals novel mechanisms and targets. Science Advances. 7. PMID 33523961 DOI: 10.1126/sciadv.abb5398  1
2020 Wang M, Li A, Sekiya M, Beckmann ND, Quan X, Schrode N, Fernando MB, Yu A, Zhu L, Cao J, Lyu L, Horgusluoglu E, Wang Q, Guo L, Wang YS, ... ... Haroutunian V, et al. Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer's Disease. Neuron. PMID 33238137 DOI: 10.1016/j.neuron.2020.11.002  1
2020 Hertzberg L, Maggio N, Muler I, Yitzhaky A, Majer M, Haroutunian V, Zuk O, Katsel P, Domany E, Weiser M. Comprehensive Gene Expression Analysis Detects Global Reduction of Proteasome Subunits in Schizophrenia. Schizophrenia Bulletin. PMID 33141894 DOI: 10.1093/schbul/sbaa160  1
2020 Pantazopoulos H, Katsel P, Haroutunian V, Chelini G, Klengel T, Berretta S. Molecular Signature of Extracellular Matrix Pathology in Schizophrenia. The European Journal of Neuroscience. PMID 33070392 DOI: 10.1111/ejn.15009  1
2020 Akrivos J, Zhu CW, Haroutunian V. Role of cumulative biological risk in mediating socioeconomic disparities in cognitive function in the elderly: a mediation analysis. Bmj Open. 10: e035847. PMID 32948549 DOI: 10.1136/Bmjopen-2019-035847  0.01
2020 Beckmann ND, Lin WJ, Wang M, Cohain AT, Charney AW, Wang P, Ma W, Wang YC, Jiang C, Audrain M, Comella PH, Fakira AK, Hariharan SP, Belbin GM, Girdhar K, ... ... Haroutunian V, et al. Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease. Nature Communications. 11: 3942. PMID 32770063 DOI: 10.1038/S41467-020-17405-Z  1
2020 Wang H, Dey KK, Chen PC, Li Y, Niu M, Cho JH, Wang X, Bai B, Jiao Y, Chepyala SR, Haroutunian V, Zhang B, Beach TG, Peng J. Integrated analysis of ultra-deep proteomes in cortex, cerebrospinal fluid and serum reveals a mitochondrial signature in Alzheimer's disease. Molecular Neurodegeneration. 15: 43. PMID 32711556 DOI: 10.1186/S13024-020-00384-6  1
2020 Cao J, Huang M, Guo L, Zhu L, Hou J, Zhang L, Pero A, Ng S, El Gaamouch F, Elder G, Sano M, Goate A, Tcw J, Haroutunian V, Zhang B, et al. MicroRNA-195 rescues ApoE4-induced cognitive deficits and lysosomal defects in Alzheimer's disease pathogenesis. Molecular Psychiatry. PMID 32632205 DOI: 10.1038/S41380-020-0824-3  1
2020 Bai B, Wang X, Li Y, Chen PC, Yu K, Dey KK, Yarbro JM, Han X, Lutz BM, Rao S, Jiao Y, Sifford JM, Han J, Wang M, Tan H, ... ... Haroutunian V, et al. Deep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer's Disease Progression. Neuron. 106: 700. PMID 32437656 DOI: 10.1016/j.neuron.2020.04.031  1
2020 Beeri MS, Uribarri J, Cai W, Buchman AS, Haroutunian V. Human Brain and Serum Advanced Glycation End Products are Highly Correlated: Preliminary Results of Their Role in Alzheimer Disease and Type 2 Diabetes. Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. 26: 576-577. PMID 32396777 DOI: 10.4158/1934-2403-26.5.576  1
2020 Frajman A, Maggio N, Muler I, Haroutunian V, Katsel P, Yitzhaky A, Weiser M, Hertzberg L. Gene expression meta-analysis reveals the down-regulation of three GABA receptor subunits in the superior temporal gyrus of patients with schizophrenia. Schizophrenia Research. PMID 32376074 DOI: 10.1016/J.Schres.2020.04.027  1
2020 Johnson ECB, Dammer EB, Duong DM, Ping L, Zhou M, Yin L, Higginbotham LA, Guajardo A, White B, Troncoso JC, Thambisetty M, Montine TJ, Lee EB, Trojanowski JQ, Beach TG, ... ... Haroutunian V, et al. Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation. Nature Medicine. PMID 32284590 DOI: 10.1038/S41591-020-0815-6  1
2020 Woo YJ, Roussos P, Haroutunian V, Katsel P, Gandy S, Schadt EE, Zhu J. Comparison of brain connectomes by MRI and genomics and its implication in Alzheimer's disease. Bmc Medicine. 18: 23. PMID 32024511 DOI: 10.1186/S12916-019-1488-1  1
2020 Bai B, Wang X, Li Y, Chen PC, Yu K, Dey KK, Yarbro JM, Han X, Lutz BM, Rao S, Jiao Y, Sifford JM, Han J, Wang M, Tan H, ... ... Haroutunian V, et al. Deep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer's Disease Progression. Neuron. PMID 31926610 DOI: 10.1016/J.Neuron.2019.12.015  1
2019 Pulina MV, Hopkins M, Haroutunian V, Greengard P, Bustos V. C99 selectively accumulates in vulnerable neurons in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31677937 DOI: 10.1016/J.Jalz.2019.09.002  1
2019 Katsel P, Haroutunian V. Is Alzheimer disease a failure of mobilizing immune defense? Lessons from cognitively fit oldest-old. Dialogues in Clinical Neuroscience. 21: 7-19. PMID 31607776  1
2019 Hoffman GE, Bendl J, Voloudakis G, Montgomery KS, Sloofman L, Wang YC, Shah HR, Hauberg ME, Johnson JS, Girdhar K, Song L, Fullard JF, Kramer R, Hahn CG, Gur R, ... ... Haroutunian V, et al. CommonMind Consortium provides transcriptomic and epigenomic data for Schizophrenia and Bipolar Disorder. Scientific Data. 6: 180. PMID 31551426 DOI: 10.1038/S41597-019-0183-6  1
2019 Signaevsky M, Prastawa M, Farrell K, Tabish N, Baldwin E, Han N, Iida MA, Koll J, Bryce C, Purohit D, Haroutunian V, McKee AC, Stein TD, White CL, Walker J, et al. Artificial intelligence in neuropathology: deep learning-based assessment of tauopathy. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 30770886 DOI: 10.1038/S41374-019-0202-4  1
2019 Katsel P, Roussos P, Fam P, Khan S, Tan W, Hirose T, Nakagawa S, Pletnikov MV, Haroutunian V. The expression of long noncoding RNA NEAT1 is reduced in schizophrenia and modulates oligodendrocytes transcription. Npj Schizophrenia. 5: 3. PMID 30696826 DOI: 10.1038/s41537-019-0071-2  1
2019 Fullard JF, Charney AW, Voloudakis G, Uzilov AV, Haroutunian V, Roussos P. Assessment of somatic single-nucleotide variation in brain tissue of cases with schizophrenia. Translational Psychiatry. 9: 21. PMID 30655504 DOI: 10.1038/S41398-018-0342-0  1
2019 Robinson A, Lubitz I, Atrakchi-Baranes D, Licht-Murava A, Katsel P, Leroith D, Liraz-Zaltsman S, Haroutunian V, Beeri MS. Combination of Insulin with a GLP1 Agonist Is Associated with Better Memory and Normal Expression of Insulin Receptor Pathway Genes in a Mouse Model of Alzheimer's Disease. Journal of Molecular Neuroscience : Mn. PMID 30635783 DOI: 10.1007/S12031-019-1257-9  1
2019 Smith RG, Pishva E, Shireby G, Smith AR, Hannon E, Sharp AJ, Mastroeni Df, Schalkwyk LC, Haroutunian V, Coleman PD, Bennett DA, Hove DLAvd, Jager PLD, Mill J, Lunnon K. O4‐10‐06: Integrated Genetic‐Epigenetic Analyses Of Alzheimer'S Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4799  1
2019 Cao J, Hou J, Zhu L, Zhang L, Gaamouch FE, Zhong MB, Elder G, Sano M, Haroutunian V, Cai D. P2-250: Exploring A Role For Microrna195 (Mir195) As A Potential Alzheimer'S Disease Biomarker Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.2657  1
2019 Charney A, Fullard J, Hauberg ME, Haroutunian V, Roussos P. Exploring The Somatic Variation In Schizophrenia European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2017.08.283  1
2018 Katsel P, Roussos P, Beeri MS, Gama-Sosa MA, Gandy S, Khan S, Haroutunian V. Parahippocampal gyrus expression of endothelial and insulin receptor signaling pathway genes is modulated by Alzheimer's disease and normalized by treatment with anti-diabetic agents. Plos One. 13: e0206547. PMID 30383799 DOI: 10.1371/Journal.Pone.0206547  1
2018 Sullivan CR, Mielnik CA, O'Donovan SM, Funk AJ, Bentea E, DePasquale EA, Alganem K, Wen Z, Haroutunian V, Katsel P, Ramsey AJ, Meller J, McCullumsmith RE. Connectivity Analyses of Bioenergetic Changes in Schizophrenia: Identification of Novel Treatments. Molecular Neurobiology. PMID 30338483 DOI: 10.1007/S12035-018-1390-4  1
2018 Huang F, Wang M, Liu R, Wang JZ, Schadt E, Haroutunian V, Katsel P, Zhang B, Wang X. CDT2-controlled cell cycle reentry regulates the pathogenesis of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30321504 DOI: 10.1016/J.Jalz.2018.08.013  1
2018 Raj T, Li YI, Wong G, Humphrey J, Wang M, Ramdhani S, Wang YC, Ng B, Gupta I, Haroutunian V, Schadt EE, Young-Pearse T, Mostafavi S, Zhang B, Sklar P, et al. Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility. Nature Genetics. PMID 30297968 DOI: 10.1038/S41588-018-0238-1  1
2018 Wang M, Beckmann ND, Roussos P, Wang E, Zhou X, Wang Q, Ming C, Neff R, Ma W, Fullard JF, Hauberg ME, Bendl J, Peters MA, Logsdon B, Wang P, ... ... Haroutunian V, et al. The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease. Scientific Data. 5: 180185. PMID 30204156 DOI: 10.1038/Sdata.2018.185  1
2018 Bryois J, Garrett ME, Song L, Safi A, Giusti-Rodriguez P, Johnson GD, Shieh AW, Buil A, Fullard JF, Roussos P, Sklar P, Akbarian S, Haroutunian V, Stockmeier CA, Wray GA, et al. Evaluation of chromatin accessibility in prefrontal cortex of individuals with schizophrenia. Nature Communications. 9: 3121. PMID 30087329 DOI: 10.1038/S41467-018-05379-Y  1
2018 Fullard JF, Giambartolomei C, Hauberg ME, Xu K, Voloudakis G, Shao Z, Bare C, Dudley JT, Mattheisen M, Robakis NK, Haroutunian V, Roussos P. Open chromatin profiling of human postmortem brain infers functional roles for non-coding schizophrenia loci. Human Molecular Genetics. PMID 29982455 DOI: 10.1093/hmg/ddy229  1
2018 Readhead B, Haure-Mirande JV, Funk CC, Richards MA, Shannon P, Haroutunian V, Sano M, Liang WS, Beckmann ND, Price ND, Reiman EM, Schadt EE, Ehrlich ME, Gandy S, Dudley JT. Multiscale Analysis of Independent Alzheimer's Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus. Neuron. PMID 29937276 DOI: 10.1016/J.Neuron.2018.05.023  1
2018 Smith RG, Hannon E, De Jager PL, Chibnik L, Lott SJ, Condliffe D, Smith AR, Haroutunian V, Troakes C, Al-Sarraj S, Bennett DA, Powell J, Lovestone S, Schalkwyk L, Mill J, et al. Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29550519 DOI: 10.1016/J.Jalz.2018.01.017  1
2018 Poirel O, Mella S, Videau C, Ramet L, Davoli MA, Herzog E, Katsel P, Mechawar N, Haroutunian V, Epelbaum J, Daumas S, El Mestikawy S. Moderate decline in select synaptic markers in the prefrontal cortex (BA9) of patients with Alzheimer's disease at various cognitive stages. Scientific Reports. 8: 938. PMID 29343737 DOI: 10.1038/S41598-018-19154-Y  1
2018 Guerrero-Berroa E, Schmeidler J, Haroutunian V, Arneson J, West R, Beeri MS, Sano M, Silverman JM. P2-607: Depressive Symptoms Predict Cognitive Decline In Older Adults Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1303  1
2017 McKenzie AT, Moyon S, Wang M, Katsyv I, Song WM, Zhou X, Dammer EB, Duong DM, Aaker J, Zhao Y, Beckmann N, Wang P, Zhu J, Lah JJ, Seyfried NT, ... ... Haroutunian V, et al. Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer's disease. Molecular Neurodegeneration. 12: 82. PMID 29110684 DOI: 10.1186/S13024-017-0219-3  1
2017 Katsel P, Fam P, Tan W, Khan S, Yang C, Jouroukhin Y, Rudchenko S, Pletnikov MV, Haroutunian V. Overexpression of Truncated Human DISC1 Induces Appearance of Hindbrain Oligodendroglia in the Forebrain During Development. Schizophrenia Bulletin. PMID 28981898 DOI: 10.1093/Schbul/Sbx106  1
2017 Katsel P, Roussos P, Pletnikov M, Haroutunian V. Microvascular anomaly conditions in psychiatric disease. Schizophrenia - angiogenesis connection. Neuroscience and Biobehavioral Reviews. PMID 28396239 DOI: 10.1016/J.Neubiorev.2017.04.003  1
2017 Fullard JF, Giambartolomei C, Hauberg ME, Xu K, Voloudakis G, Shao Z, Bare C, Dudley JT, Mattheisen M, Robakis NK, Haroutunian V, Roussos P. Open chromatin profiling of human postmortem brain infers functional roles for non-coding schizophrenia loci. Human Molecular Genetics. PMID 28335009 DOI: 10.1093/Hmg/Ddx103  1
2017 Atrakchi-Baranes D, Lubitz I, Chen S, Katsel P, Liraz-Zaltsman S, Licht T, Sharvit-Ginon I, Goldman SE, Cooper I, Haroutunian V, Beeri MS. Combination Therapy Of Type 2 Diabetes Medications As A Treatment Target For Alzheimer Disease Alzheimers & Dementia. 13: 648. DOI: 10.1016/J.Jalz.2017.06.757  1
2017 Hauberg ME, Fullard J, Giambartolomei C, Xu K, Bare C, Dudley J, Mattheisen M, Pickrell J, Haroutunian V, Roussos P. Cell-Type Specific open Chromatin Profiling in Human Postmortem Brain Infers Functional Roles For Non-Coding Schizophrenia LOCI European Neuropsychopharmacology. 27. DOI: 10.1016/J.Euroneuro.2016.09.483  1
2016 Shively SB, Edgerton SL, Iacono D, Purohit DP, Qu BX, Haroutunian V, Davis KL, Diaz-Arrastia R, Perl DP. Localized cortical chronic traumatic encephalopathy pathology after single, severe axonal injury in human brain. Acta Neuropathologica. PMID 27885490 DOI: 10.1007/S00401-016-1649-7  1
2016 Wang M, Roussos P, McKenzie A, Zhou X, Kajiwara Y, Brennand KJ, De Luca GC, Crary JF, Casaccia P, Buxbaum JD, Ehrlich M, Gandy S, Goate A, Katsel P, Schadt E, ... Haroutunian V, et al. Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer's disease. Genome Medicine. 8: 104. PMID 27799057 DOI: 10.1186/S13073-016-0355-3  1
2016 Mueller TM, Yates SD, Haroutunian V, Meador-Woodruff JH. Altered fucosyltransferase expression in the superior temporal gyrus of elderly patients with schizophrenia. Schizophrenia Research. PMID 27773385 DOI: 10.1016/J.Schres.2016.10.024  1
2016 Fromer M, Roussos P, Sieberts SK, Johnson JS, Kavanagh DH, Perumal TM, Ruderfer DM, Oh EC, Topol A, Shah HR, Klei LL, Kramer R, Pinto D, Gümüş ZH, Cicek AE, ... ... Haroutunian V, et al. Gene expression elucidates functional impact of polygenic risk for schizophrenia. Nature Neuroscience. PMID 27668389 DOI: 10.1038/Nn.4399  1
2016 McCullumsmith RE, O'Donovan SM, Drummond JB, Benesh FS, Simmons M, Roberts R, Lauriat T, Haroutunian V, Meador-Woodruff JH. Shaping plasticity: Alterations in glutamate transporter localization as a pathophysiological mechanism in severe mental illness. Molecular Psychiatry. 21: 723. PMID 27198660 DOI: 10.1038/Mp.2016.79  1
2016 Scheckel C, Drapeau E, Frias MA, Park CY, Fak J, Zucker-Scharff I, Kou Y, Haroutunian V, Ma'ayan A, Buxbaum JD, Darnell RB. Regulatory consequences of neuronal ELAV-like protein binding to coding and non-coding RNAs in human brain. Elife. 5. PMID 26894958 DOI: 10.7554/Elife.10421  1
2016 Pinner AL, Tucholski J, Haroutunian V, McCullumsmith RE, Meador-Woodruff JH. Decreased protein S-palmitoylation in dorsolateral prefrontal cortex in schizophrenia. Schizophrenia Research. PMID 26876311 DOI: 10.1016/J.Schres.2016.01.054  1
2016 Fullard JF, Halene TB, Giambartolomei C, Haroutunian V, Akbarian S, Roussos P. Understanding the genetic liability to schizophrenia through the neuroepigenome. Schizophrenia Research. PMID 26827128 DOI: 10.1016/J.Schres.2016.01.039  1
2016 Watson CT, Roussos P, Garg P, Ho DJ, Azam N, Katsel PL, Haroutunian V, Sharp AJ. Genome-wide DNA methylation profiling in the superior temporal gyrus reveals epigenetic signatures associated with Alzheimer's disease. Genome Medicine. 8: 5. PMID 26803900 DOI: 10.1186/S13073-015-0258-8  1
2016 Watson CT, Roussos P, Garg P, Ho DJ, Azam N, Katsel PL, Haroutunian V, Sharp AJ. Genome-wide12 DNA methylation profiling in the superior temporal gyrus reveals epigenetic signatures associated with Alzheimer's disease. Genome Medicine. 8: 5. PMID 26787419 DOI: 10.1186/s13073-015-0258-8  1
2016 Fá M, Puzzo D, Piacentini R, Staniszewski A, Zhang H, Baltrons MA, Li Puma DD, Chatterjee I, Li J, Saeed F, Berman HL, Ripoli C, Gulisano W, Gonzalez J, Tian H, ... ... Haroutunian V, et al. Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory. Scientific Reports. 6: 19393. PMID 26786552 DOI: 10.1038/Srep19393  1
2016 Readhead B, Haure-Mirande JV, Zhang B, Haroutunian V, Gandy S, Schadt EE, Dudley JT, Ehrlich ME. Molecular systems evaluation of oligomerogenic APP(E693Q) and fibrillogenic APP(KM670/671NL)/PSEN1(Δexon9) mouse models identifies shared features with human Alzheimer's brain molecular pathology. Molecular Psychiatry. PMID 26782051 DOI: 10.1038/Mp.2015.215  1
2016 Readhead B, Haure-Mirande JV, Zhang B, Haroutunian V, Gandy S, Schadt EE, Dudley JT, Ehrlich ME. Molecular systems evaluation of oligomerogenic APPE693Q and fibrillogenic APPKM670/671NL/PSEN1?exon9 mouse models identifies shared features with human Alzheimer’s brain molecular pathology Molecular Psychiatry. DOI: 10.1038/mp.2015.215  1
2015 Tsang J, Fullard JF, Giakoumaki SG, Katsel P, Eirini Karagiorga V, Greenwood TA, Braff DL, Siever LJ, Bitsios P, Haroutunian V, Roussos P. Erratum: The relationship between dopamine receptor D1 and cognitive performance. Npj Schizophrenia. 1: 15018. PMID 27336628 DOI: 10.1038/npjschz.2015.18  1
2015 Tsang J, Fullard JF, Giakoumaki SG, Katsel P, Katsel P, Karagiorga VE, Greenwood TA, Braff DL, Siever LJ, Bitsios P, Haroutunian V, Roussos P. The relationship between dopamine receptor D1 and cognitive performance. Npj Schizophrenia. 1: 14002. PMID 27336024 DOI: 10.1038/npjschz.2014.2  1
2015 Bhambhvani HP, Simmons M, Haroutunian V, Meador-Woodruff JH. Decreased expression of cortactin in the schizophrenia brain. Neuroreport. PMID 26691754 DOI: 10.1097/Wnr.0000000000000514  1
2015 Readhead B, Haure-Mirande JV, Zhang B, Haroutunian V, Gandy S, Schadt EE, Dudley JT, Ehrlich ME. Molecular systems evaluation of oligomerogenic APP(E693Q) and fibrillogenic APP(KM670/671NL)/PSEN1(Δexon9) mouse models identifies shared features with human Alzheimer's brain molecular pathology. Molecular Psychiatry. PMID 26552589 DOI: 10.1038/Mp.2015.167  1
2015 McCullumsmith RE, O'Donovan SM, Drummond JB, Benesh FS, Simmons M, Roberts R, Lauriat T, Haroutunian V, Meador-Woodruff JH. Cell-specific abnormalities of glutamate transporters in schizophrenia: sick astrocytes and compensating relay neurons? Molecular Psychiatry. PMID 26416546 DOI: 10.1038/Mp.2015.148  1
2015 Zhu L, Zhong M, Elder GA, Sano M, Holtzman DM, Gandy S, Cardozo C, Haroutunian V, Robakis NK, Cai D. Phospholipid dysregulation contributes to ApoE4-associated cognitive deficits in Alzheimer's disease pathogenesis. Proceedings of the National Academy of Sciences of the United States of America. 112: 11965-70. PMID 26372964 DOI: 10.1073/Pnas.1510011112  1
2015 Mueller TM, Remedies CE, Haroutunian V, Meador-Woodruff JH. Abnormal subcellular localization of GABAA receptor subunits in schizophrenia brain. Translational Psychiatry. 5: e612. PMID 26241350 DOI: 10.1038/Tp.2015.102  1
2015 Scott MR, Rubio MD, Haroutunian V, Meador-Woodruff JH. Protein Expression of Proteasome Subunits in Elderly Patients with Schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26202105 DOI: 10.1038/Npp.2015.219  1
2015 Kippe JM, Mueller TM, Haroutunian V, Meador-Woodruff JH. Abnormal N-acetylglucosaminyltransferase expression in prefrontal cortex in schizophrenia. Schizophrenia Research. PMID 26104473 DOI: 10.1016/J.Schres.2015.06.002  1
2015 O'Donovan SM, Hasselfeld K, Bauer D, Simmons M, Roussos P, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE. Glutamate transporter splice variant expression in an enriched pyramidal cell population in schizophrenia. Translational Psychiatry. 5: e579. PMID 26057049 DOI: 10.1038/Tp.2015.74  1
2015 Sullivan CR, Funk AJ, Shan D, Haroutunian V, McCullumsmith RE. Decreased chloride channel expression in the dorsolateral prefrontal cortex in schizophrenia. Plos One. 10: e0123158. PMID 25826365 DOI: 10.1371/Journal.Pone.0123158  1
2015 Zhao W, Wang J, Varghese M, Ho L, Mazzola P, Haroutunian V, Katsel PL, Gibson GE, Levine S, Dubner L, Pasinetti GM. Impaired mitochondrial energy metabolism as a novel risk factor for selective onset and progression of dementia in oldest-old subjects. Neuropsychiatric Disease and Treatment. 11: 565-74. PMID 25784811 DOI: 10.2147/NDT.S74898  1
2015 Hertzberg L, Katsel P, Roussos P, Haroutunian V, Domany E. Integration of gene expression and GWAS results supports involvement of calcium signaling in Schizophrenia. Schizophrenia Research. 164: 92-9. PMID 25702973 DOI: 10.1016/J.Schres.2015.02.001  1
2015 Bristow GC, Bostrom JA, Haroutunian V, Sodhi MS. Sex differences in GABAergic gene expression occur in the anterior cingulate cortex in schizophrenia. Schizophrenia Research. PMID 25660468 DOI: 10.1016/J.Schres.2015.01.025  1
2015 Scheckel C, Drapeau E, Frias MA, Park CY, Fak J, Zucker-Scharff I, Kou Y, Haroutunian V, Ma'ayan A, Buxbaum JD, Darnell RB. Author response: Regulatory consequences of neuronal ELAV-like protein binding to coding and non-coding RNAs in human brain Elife. DOI: 10.7554/Elife.10421.041  1
2015 Scott MR, Rubio MD, Haroutunian V, Meador-Woodruff JH. Protein Expression of Proteasome Subunits in Elderly Patients with Schizophrenia Neuropsychopharmacology. DOI: 10.1038/npp.2015.219  1
2015 Lunnon K, Smith R, Hannon E, Smith A, Schalkwyk LC, Haroutunian V, Mill J. Systems-level evidence for epigenetic dysfunction in Alzheimer’s disease Alzheimers & Dementia. 11: 228. DOI: 10.1016/J.Jalz.2015.07.261  1
2014 Roussos P, Katsel P, Fam P, Tan W, Purohit DP, Haroutunian V. The triggering receptor expressed on myeloid cells 2 (TREM2) is associated with enhanced inflammation, neuropathological lesions and increased risk for Alzheimer's dementia. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 25499537 DOI: 10.1016/J.Jalz.2014.10.013  1
2014 Bharadwaj R, Peter CJ, Jiang Y, Roussos P, Vogel-Ciernia A, Shen EY, Mitchell AC, Mao W, Whittle C, Dincer A, Jakovcevski M, Pothula V, Rasmussen TP, Giakoumaki SG, Bitsios P, ... ... Haroutunian V, et al. Conserved higher-order chromatin regulates NMDA receptor gene expression and cognition. Neuron. 84: 997-1008. PMID 25467983 DOI: 10.1016/J.Neuron.2014.10.032  1
2014 Funk AJ, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE. Increased G protein-coupled receptor kinase (GRK) expression in the anterior cingulate cortex in schizophrenia. Schizophrenia Research. 159: 130-5. PMID 25153362 DOI: 10.1016/J.Schres.2014.07.040  1
2014 Lunnon K, Smith R, Hannon E, De Jager PL, Srivastava G, Volta M, Troakes C, Al-Sarraj S, Burrage J, Macdonald R, Condliffe D, Harries LW, Katsel P, Haroutunian V, Kaminsky Z, et al. Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease. Nature Neuroscience. 17: 1164-70. PMID 25129077 DOI: 10.1038/Nn.3782  1
2014 Simon RA, Shirani H, Aslund KO, Bäck M, Haroutunian V, Gandy S, Nilsson KP. Pentameric thiophene-based ligands that spectrally discriminate amyloid-β and tau aggregates display distinct solvatochromism and viscosity-induced spectral shifts. Chemistry (Weinheim An Der Bergstrasse, Germany). 20: 12537-43. PMID 25111601 DOI: 10.1002/Chem.201402890  1
2014 Haroutunian V, Katsel P, Roussos P, Davis KL, Altshuler LL, Bartzokis G. Myelination, oligodendrocytes, and serious mental illness. Glia. 62: 1856-77. PMID 25056210 DOI: 10.1002/Glia.22716  1
2014 Jun G, Asai H, Zeldich E, Drapeau E, Chen C, Chung J, Park JH, Kim S, Haroutunian V, Foroud T, Kuwano R, Haines JL, Pericak-Vance MA, Schellenberg GD, Lunetta KL, et al. PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation. Annals of Neurology. 76: 379-92. PMID 25043464 DOI: 10.1002/Ana.24219  1
2014 McGuire JL, Hammond JH, Yates SD, Chen D, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE. Altered serine/threonine kinase activity in schizophrenia. Brain Research. 1568: 42-54. PMID 24780530 DOI: 10.1016/J.Brainres.2014.04.029  1
2014 Lubitz I, Haroutunian V, Katsel P, Leroith D, Landa N, Castel D, Shaish A, Shnerb R, Schnaider-Beeri M. Non-viability of crossing the Alzheimer mouse model Tg2576 with the type 2 diabetes mouse model ob/ob. Neurobiology of Aging. 35: e19-20. PMID 24581479 DOI: 10.1016/J.Neurobiolaging.2014.01.138  1
2014 Pinner AL, Haroutunian V, Meador-Woodruff JH. Alterations of the myristoylated, alanine-rich C kinase substrate (MARCKS) in prefrontal cortex in schizophrenia. Schizophrenia Research. 154: 36-41. PMID 24568864 DOI: 10.1016/J.Schres.2014.02.003  1
2014 Roussos P, Haroutunian V. Schizophrenia: susceptibility genes and oligodendroglial and myelin related abnormalities. Frontiers in Cellular Neuroscience. 8: 5. PMID 24478629 DOI: 10.3389/Fncel.2014.00005  1
2014 Huynh JL, Garg P, Thin TH, Yoo S, Dutta R, Trapp BD, Haroutunian V, Zhu J, Donovan MJ, Sharp AJ, Casaccia P. Epigenome-wide differences in pathology-free regions of multiple sclerosis-affected brains. Nature Neuroscience. 17: 121-30. PMID 24270187 DOI: 10.1038/Nn.3588  1
2014 Mueller TM, Haroutunian V, Meador-Woodruff JH. N-Glycosylation of GABAA receptor subunits is altered in Schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 528-37. PMID 23917429 DOI: 10.1038/Npp.2013.190  1
2014 Haroutunian V. A Systems Biology Approach Toward Understanding Schizophrenia Schizophrenia Research. 153. DOI: 10.1016/S0920-9964(14)70031-3  0.01
2014 Lunnon K, Smith R, Hannon E, Volta M, Troakes C, Haroutunian V, Katsel P, Al-Sarraj S, Lovestone S, Schalkwyk L, Mill J. Cross-Tissue Methylomic Profiling In Alzheimer'S Disease Alzheimers & Dementia. 10: 215. DOI: 10.1016/J.Jalz.2014.04.288  1
2014 Riccio DC, Haroutunian V. Some approaches to the alleviation of ontogenetic memory deficits Ontogeny of Learning and Memory. 289-310.  1
2013 Mamdani M, McMichael GO, Gadepalli V, Williamson V, Parker EK, Haroutunian V, Vladimirov VI. Differential regulation of schizophrenia-associated microRNA gene function by variable number tandem repeats (VNTR) polymorphism. Schizophrenia Research. 151: 284-6. PMID 24210531 DOI: 10.1016/J.Schres.2013.10.024  1
2013 Katsel P, Tan W, Fam P, Purohit DP, Haroutunian V. Cell cycle checkpoint abnormalities during dementia: A plausible association with the loss of protection against oxidative stress in Alzheimer's disease [corrected]. Plos One. 8: e68361. PMID 23861893 DOI: 10.1371/Journal.Pone.0068361  1
2013 Tucholski J, Simmons MS, Pinner AL, McMillan LD, Haroutunian V, Meador-Woodruff JH. N-linked glycosylation of cortical N-methyl-D-aspartate and kainate receptor subunits in schizophrenia. Neuroreport. 24: 688-91. PMID 23820740 DOI: 10.1097/Wnr.0B013E328363Bd8A  1
2013 Akbarian S, Beeri MS, Haroutunian V. Epigenetic determinants of healthy and diseased brain aging and cognition. Jama Neurology. 70: 711-8. PMID 23571692 DOI: 10.1001/Jamaneurol.2013.1459  1
2013 Rubio MD, Wood K, Haroutunian V, Meador-Woodruff JH. Dysfunction of the ubiquitin proteasome and ubiquitin-like systems in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 1910-20. PMID 23571678 DOI: 10.1038/Npp.2013.84  1
2013 Drummond JB, Tucholski J, Haroutunian V, Meador-Woodruff JH. Transmembrane AMPA receptor regulatory protein (TARP) dysregulation in anterior cingulate cortex in schizophrenia. Schizophrenia Research. 147: 32-8. PMID 23566497 DOI: 10.1016/J.Schres.2013.03.010  1
2013 Tucholski J, Simmons MS, Pinner AL, Haroutunian V, McCullumsmith RE, Meador-Woodruff JH. Abnormal N-linked glycosylation of cortical AMPA receptor subunits in schizophrenia. Schizophrenia Research. 146: 177-83. PMID 23462048 DOI: 10.1016/J.Schres.2013.01.031  1
2013 Gandy S, Haroutunian V, DeKosky ST, Sano M, Schadt EE. CR1 and the "vanishing amyloid" hypothesis of Alzheimer's disease. Biological Psychiatry. 73: 393-5. PMID 23399469 DOI: 10.1016/J.Biopsych.2013.01.013  1
2013 Shan D, Lucas EK, Drummond JB, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE. Abnormal expression of glutamate transporters in temporal lobe areas in elderly patients with schizophrenia. Schizophrenia Research. 144: 1-8. PMID 23356950 DOI: 10.1016/J.Schres.2012.12.019  1
2013 Zhao W, Ho L, Varghese M, Yemul S, Dams-O'Connor K, Gordon W, Knable L, Freire D, Haroutunian V, Pasinetti GM. Decreased level of olfactory receptors in blood cells following traumatic brain injury and potential association with tauopathy. Journal of Alzheimer's Disease : Jad. 34: 417-29. PMID 23241557 DOI: 10.3233/Jad-121894  1
2013 Roussos P, Katsel P, Davis KL, Giakoumaki SG, Lencz T, Malhotra AK, Siever LJ, Bitsios P, Haroutunian V. Convergent findings for abnormalities of the NF-κB signaling pathway in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 533-9. PMID 23132271 DOI: 10.1038/Npp.2012.215  1
2013 Hammond JC, Meador-Woodruff JH, Haroutunian V, McCullumsmith RE. Flow chart of endoplasmic reticulum isolation. Plos One. DOI: 10.1371/Journal.Pone.0039190.G001  1
2013 Katsel P, Tan W, Fam P, Purohit DP, Haroutunian V. Correction:Cell cycle checkpoint abnormalities during dementia: A plausible association with the loss of protection against oxidative stress in Alzheimer's disease. (PLoS ONE) Plos One. 8. DOI: 10.1371/annotation/59ecb64c-1f53-4d8a-903c-2f835e78bd13  1
2012 Hallacoglu B, Sassaroli A, Wysocki M, Guerrero-Berroa E, Schnaider Beeri M, Haroutunian V, Shaul M, Rosenberg IH, Troen AM, Fantini S. Absolute measurement of cerebral optical coefficients, hemoglobin concentration and oxygen saturation in old and young adults with near-infrared spectroscopy. Journal of Biomedical Optics. 17: 081406-1. PMID 23224167 DOI: 10.1117/1.Jbo.17.8.081406  1
2012 Drummond JB, Simmons M, Haroutunian V, Meador-Woodruff JH. Upregulation of cornichon transcripts in the dorsolateral prefrontal cortex in schizophrenia. Neuroreport. 23: 1031-4. PMID 23103966 DOI: 10.1097/Wnr.0B013E32835Ad229  1
2012 Silverman JM, Schmeidler J, Beeri MS, Rosendorff C, Sano M, Grossman HT, Carrión-Baralt JR, Bespalova IN, West R, Haroutunian V. C-reactive protein and familial risk for dementia: a phenotype for successful cognitive aging. Neurology. 79: 1116-23. PMID 22895578 DOI: 10.1212/Wnl.0B013E3182698C89  1
2012 Roussos P, Katsel P, Davis KL, Siever LJ, Haroutunian V. A system-level transcriptomic analysis of schizophrenia using postmortem brain tissue samples. Archives of General Psychiatry. 69: 1205-13. PMID 22868662 DOI: 10.1001/Archgenpsychiatry.2012.704  1
2012 Carty NC, Xu J, Kurup P, Brouillette J, Goebel-Goody SM, Austin DR, Yuan P, Chen G, Correa PR, Haroutunian V, Pittenger C, Lombroso PJ. The tyrosine phosphatase STEP: implications in schizophrenia and the molecular mechanism underlying antipsychotic medications. Translational Psychiatry. 2: e137. PMID 22781170 DOI: 10.1038/Tp.2012.63  1
2012 Hammond JC, Meador-Woodruff JH, Haroutunian V, McCullumsmith RE. AMPA receptor subunit expression in the endoplasmic reticulum in frontal cortex of elderly patients with schizophrenia. Plos One. 7: e39190. PMID 22720072 DOI: 10.1371/Journal.Pone.0039190  1
2012 Ho L, Yemul S, Knable L, Katsel P, Zhao R, Haroutunian V, Pasinetti GM. Insulin receptor expression and activity in the brains of nondiabetic sporadic Alzheimer's disease cases. International Journal of Alzheimer's Disease. 2012: 321280. PMID 22666619 DOI: 10.1155/2012/321280  1
2012 Ho L, Zhao W, Dams-O'Connor K, Tang CY, Gordon W, Peskind ER, Yemul S, Haroutunian V, Pasinetti GM. Elevated plasma MCP-1 concentration following traumatic brain injury as a potential "predisposition" factor associated with an increased risk for subsequent development of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 31: 301-13. PMID 22543850 DOI: 10.3233/Jad-2012-120598  1
2012 Nelson PT, Alafuzoff I, Bigio EH, Bouras C, Braak H, Cairns NJ, Castellani RJ, Crain BJ, Davies P, Del Tredici K, Duyckaerts C, Frosch MP, Haroutunian V, Hof PR, Hulette CM, et al. Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature. Journal of Neuropathology and Experimental Neurology. 71: 362-81. PMID 22487856 DOI: 10.1097/Nen.0B013E31825018F7  1
2012 Rubio MD, Haroutunian V, Meador-Woodruff JH. Abnormalities of the Duo/Ras-related C3 botulinum toxin substrate 1/p21-activated kinase 1 pathway drive myosin light chain phosphorylation in frontal cortex in schizophrenia. Biological Psychiatry. 71: 906-14. PMID 22458949 DOI: 10.1016/J.Biopsych.2012.02.006  1
2012 Ravona-Springer R, Moshier E, Schmeidler J, Godbold J, Akrivos J, Rapp M, Grossman HT, Wysocki M, Silverman JM, Haroutunian V, Beeri MS. Changes in glycemic control are associated with changes in cognition in non-diabetic elderly. Journal of Alzheimer's Disease : Jad. 30: 299-309. PMID 22426020 DOI: 10.3233/JAD-2012-120106  1
2012 Shan D, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE. Expression of equilibrative nucleoside transporter type 1 protein in elderly patients with schizophrenia. Neuroreport. 23: 224-7. PMID 22314683 DOI: 10.1097/Wnr.0B013E3283500987  1
2012 Moehle MS, Luduena RF, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE. Regional differences in expression of β-tubulin isoforms in schizophrenia. Schizophrenia Research. 135: 181-6. PMID 22264600 DOI: 10.1016/J.Schres.2011.12.010  1
2012 Beeri MS, Haroutunian V, Schmeidler J, Sano M, Fam P, Kavanaugh A, Barr AM, Honer WG, Katsel P. Synaptic protein deficits are associated with dementia irrespective of extreme old age. Neurobiology of Aging. 33: 1125.e1-8. PMID 22206847 DOI: 10.1016/J.Neurobiolaging.2011.08.017  1
2012 Funk AJ, McCullumsmith RE, Haroutunian V, Meador-Woodruff JH. Abnormal activity of the MAPK- and cAMP-associated signaling pathways in frontal cortical areas in postmortem brain in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 896-905. PMID 22048463 DOI: 10.1038/Npp.2011.267  1
2012 Roussos P, Katsel P, Davis KL, Bitsios P, Giakoumaki SG, Jogia J, Rozsnyai K, Collier D, Frangou S, Siever LJ, Haroutunian V. Molecular and genetic evidence for abnormalities in the nodes of Ranvier in schizophrenia. Archives of General Psychiatry. 69: 7-15. PMID 21893642 DOI: 10.1001/Archgenpsychiatry.2011.110  1
2012 Wysocki M, Luo X, Schmeidler J, Dahlman K, Lesser GT, Grossman H, Haroutunian V, Beeri MS. Hypertension is associated with cognitive decline in elderly people at high risk for dementia. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 20: 179-87. PMID 21814158 DOI: 10.1097/Jgp.0B013E31820Ee833  1
2012 Akram A, Schmeidler J, Katsel P, Hof PR, Haroutunian V. Association of ApoE and LRP mRNA levels with dementia and AD neuropathology. Neurobiology of Aging. 33: 628.e1-628.e14. PMID 21676498 DOI: 10.1016/J.Neurobiolaging.2011.04.010  1
2012 Beeri MS, Schmeidler J, Lesser GT, Maroukian M, West R, Leung S, Wysocki M, Perl DP, Purohit DP, Haroutunian V. Corticosteroids, but not NSAIDs, are associated with less Alzheimer neuropathology. Neurobiology of Aging. 33: 1258-64. PMID 21458888 DOI: 10.1016/J.Neurobiolaging.2011.02.011  1
2012 Haroutunian V, Wallace W, Santucci AC, Davis KL. Animal Models of Multiple Neurotransmitter Interactions in Alzheimer's Disease Brain and Memory: Modulation and Mediation of Neuroplasticity. DOI: 10.1093/acprof:oso/9780195082944.003.0007  1
2012 Haroutunian V. Similarities In The Gene And Protein Expression Substrates Of Schizophrenia And Bipolar Disorder Schizophrenia Research. 136. DOI: 10.1016/S0920-9964(12)70028-2  0.01
2012 Gibson G, Xu H, Shi Q, Haroutunian V, Chen Y, Deng H. Inactivation of a key mitochondrial protein may lead to reduced brain glucose utilization in Alzheimer's disease Alzheimers & Dementia. 8: 304. DOI: 10.1016/J.Jalz.2012.05.831  1
2012 Beeri MS, Ravona-Springer R, Schmeidler J, Katsel P, Silverman J, Haroutunian V. Diabetes characteristics and cognitive compromise: Implications for non-diabetic individuals Alzheimers & Dementia. 8: 254. DOI: 10.1016/J.Jalz.2012.05.679  1
2012 Ravona-Springer R, Schmeidler J, Wysocki M, Lesser G, Grossman H, Haroutunian V, Beeri MS. The association of glomerular filtration rate (GFR) with rate of cognitive decline Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.2161  1
2011 Xu H, Haroutunian V, Bartzokis G, Shenton ME. Oligodendrocytes in schizophrenia. Schizophrenia Research and Treatment. 2011: 249768. PMID 22937262 DOI: 10.1155/2011/249768  1
2011 Katsel P, Tan W, Abazyan B, Davis KL, Ross C, Pletnikov MV, Haroutunian V. Expression of mutant human DISC1 in mice supports abnormalities in differentiation of oligodendrocytes. Schizophrenia Research. 130: 238-49. PMID 21605958 DOI: 10.1016/J.Schres.2011.04.021  1
2011 Hammond JC, McCullumsmith RE, Haroutunian V, Meador-Woodruff JH. Endosomal trafficking of AMPA receptors in frontal cortex of elderly patients with schizophrenia. Schizophrenia Research. 130: 260-5. PMID 21576009 DOI: 10.1016/J.Schres.2011.04.029  1
2011 Ravona-Springer R, Luo X, Schmeidler J, Wysocki M, Lesser GT, Rapp MA, Dahlman K, Grossman HT, Haroutunian V, Beeri MS. The association of age with rate of cognitive decline in elderly individuals residing in supporting care facilities. Alzheimer Disease and Associated Disorders. 25: 312-6. PMID 21572311 DOI: 10.1097/Wad.0B013E31820D880E  1
2011 Sodhi MS, Simmons M, McCullumsmith R, Haroutunian V, Meador-Woodruff JH. Glutamatergic gene expression is specifically reduced in thalamocortical projecting relay neurons in schizophrenia. Biological Psychiatry. 70: 646-54. PMID 21549355 DOI: 10.1016/J.Biopsych.2011.02.022  1
2011 Radu A, Hristescu G, Katsel P, Haroutunian V, Davis KL. Microarray database mining and cell differentiation defects in schizophrenia. Advances in Experimental Medicine and Biology. 696: 67-74. PMID 21431547 DOI: 10.1007/978-1-4419-7046-6_7  1
2011 Katsel P, Byne W, Roussos P, Tan W, Siever L, Haroutunian V. Astrocyte and glutamate markers in the superficial, deep, and white matter layers of the anterior cingulate gyrus in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 1171-7. PMID 21270770 DOI: 10.1038/Npp.2010.252  1
2011 Lesser GT, Beeri MS, Schmeidler J, Purohit DP, Haroutunian V. Cholesterol and LDL relate to neuritic plaques and to APOE4 presence but not to neurofibrillary tangles. Current Alzheimer Research. 8: 303-12. PMID 21244352 DOI: 10.2174/156720511795563755  1
2011 Rapp MA, Schnaider-Beeri M, Wysocki M, Guerrero-Berroa E, Grossman HT, Heinz A, Haroutunian V. Cognitive decline in patients with dementia as a function of depression. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 19: 357-63. PMID 20808140 DOI: 10.1097/Jgp.0B013E3181E898D0  1
2011 Horesh Y, Katsel P, Haroutunian V, Domany E. Gene expression signature is shared by patients with Alzheimer's disease and schizophrenia at the superior temporal gyrus. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 18: 410-24. PMID 20695885 DOI: 10.1111/J.1468-1331.2010.03166.X  1
2011 Deep-Soboslay A, Benes FM, Haroutunian V, Ellis JK, Kleinman JE, Hyde TM. Psychiatric brain banking: three perspectives on current trends and future directions. Biological Psychiatry. 69: 104-12. PMID 20673875 DOI: 10.1016/J.Biopsych.2010.05.025  1
2011 Gan L, Min S, Cho S, Zhou Y, Haroutunian V, Seeley B, Huang E, Shen Y, Masliah E, Cole P, Ott M. Acetylation of tau contributes to tau accumulation and dysfunction Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1989  1
2011 Haroutunian V, Beeri MS, Sano M, Gandy S, Purohit D, Maroukian M, Katsel P. Oligomeric abeta associated with dementia in young-old and oldest-old persons Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1161  1
2010 Schwartz E, Wicinski B, Schmeidler J, Haroutunian V, Hof PR. CARDIOVASCULAR RISK FACTORS AFFECT HIPPOCAMPAL MICROVASCULATURE IN EARLY AD. Translational Neuroscience. 1: 292-299. PMID 21331351 DOI: 10.2478/V10134-010-0040-9  1
2010 Lyddon R, Cuppen E, Haroutunian V, Siever LJ, Dracheva S. No link of serotonin 2C receptor editing to serotonin transporter genotype. Neuroreport. 21: 1080-4. PMID 20948451 DOI: 10.1097/Wnr.0B013E32834052F0  1
2010 Naj AC, Beecham GW, Martin ER, Gallins PJ, Powell EH, Konidari I, Whitehead PL, Cai G, Haroutunian V, Scott WK, Vance JM, Slifer MA, Gwirtsman HE, Gilbert JR, Haines JL, et al. Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities. Plos Genetics. 6: e1001130. PMID 20885792 DOI: 10.1371/Journal.Pgen.1001130  1
2010 Akram A, Schmeidler J, Katsel P, Hof PR, Haroutunian V. Increased expression of RXRα in dementia: an early harbinger for the cholesterol dyshomeostasis? Molecular Neurodegeneration. 5: 36. PMID 20843353 DOI: 10.1186/1750-1326-5-36  1
2010 Kerns D, Vong GS, Barley K, Dracheva S, Katsel P, Casaccia P, Haroutunian V, Byne W. Gene expression abnormalities and oligodendrocyte deficits in the internal capsule in schizophrenia. Schizophrenia Research. 120: 150-8. PMID 20580881 DOI: 10.1016/J.Schres.2010.04.012  1
2010 Hammond JC, McCullumsmith RE, Funk AJ, Haroutunian V, Meador-Woodruff JH. Evidence for abnormal forward trafficking of AMPA receptors in frontal cortex of elderly patients with schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 2110-9. PMID 20571483 DOI: 10.1038/Npp.2010.87  1
2010 Kurup P, Zhang Y, Xu J, Venkitaramani DV, Haroutunian V, Greengard P, Nairn AC, Lombroso PJ. Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 5948-57. PMID 20427654 DOI: 10.1523/JNEUROSCI.0157-10.2010  1
2010 Kristiansen LV, Bakir B, Haroutunian V, Meador-Woodruff JH. Expression of the NR2B-NMDA receptor trafficking complex in prefrontal cortex from a group of elderly patients with schizophrenia. Schizophrenia Research. 119: 198-209. PMID 20347576 DOI: 10.1016/J.Schres.2010.02.1069  1
2010 Kajiwara Y, Franciosi S, Takahashi N, Krug L, Schmeidler J, Taddei K, Haroutunian V, Fried U, Ehrlich M, Martins RN, Gandy S, Buxbaum JD. Extensive proteomic screening identifies the obesity-related NYGGF4 protein as a novel LRP1-interactor, showing reduced expression in early Alzheimer's disease. Molecular Neurodegeneration. 5: 1. PMID 20205790 DOI: 10.1186/1750-1326-5-1  1
2010 Kristiansen LV, Patel SA, Haroutunian V, Meador-Woodruff JH. Expression of the NR2B-NMDA receptor subunit and its Tbr-1/CINAP regulatory proteins in postmortem brain suggest altered receptor processing in schizophrenia. Synapse (New York, N.Y.). 64: 495-502. PMID 20175224 DOI: 10.1002/Syn.20754  1
2010 Ravona-Springer R, Luo X, Schmeidler J, Wysocki M, Lesser G, Rapp M, Dahlman K, Grossman H, Haroutunian V, Schnaider Beeri M. Diabetes is associated with increased rate of cognitive decline in questionably demented elderly. Dementia and Geriatric Cognitive Disorders. 29: 68-74. PMID 20130405 DOI: 10.1159/000265552  1
2010 Akram A, Schmeidler J, Katsel P, Hof PR, Haroutunian V. Increased expression of cholesterol transporter ABCA1 is highly correlated with severity of dementia in AD hippocampus. Brain Research. 1318: 167-77. PMID 20079340 DOI: 10.1016/J.Brainres.2010.01.006  1
2010 Rapp MA, Schnaider-Beeri M, Purohit DP, Reichenberg A, McGurk SR, Haroutunian V, Harvey PD. Cortical neuritic plaques and hippocampal neurofibrillary tangles are related to dementia severity in elderly schizophrenia patients. Schizophrenia Research. 116: 90-6. PMID 19896333 DOI: 10.1016/J.Schres.2009.10.013  1
2010 Bauer D, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE. Abnormal glycosylation of EAAT1 and EAAT2 in prefrontal cortex of elderly patients with schizophrenia. Schizophrenia Research. 117: 92-8. PMID 19716271 DOI: 10.1016/J.Schres.2009.07.025  1
2010 Segal D, Carpenter D, Höistad M, Haroutunian V, Tang CY, Hof PR. Cingulum bundle white matter in mag-knockout mice Translational Neuroscience. 1: 131-138. DOI: 10.2478/V10134-010-0019-6  1
2010 Min SW, Cho SH, Zhou Y, Schroeder S, Haroutunian V, Seeley WW, Huang EJ, Shen Y, Masliah E, Mukherjee C, Meyers D, Cole PA, Ott M, Gan L. Erratum to Acetylation of tau inhibits its degradation and contributes to tauopathy Neuron. 68. DOI: 10.1016/J.Neuron.2010.11.013  1
2010 Beeri MS, Schmeidler J, Wysocki M, Silverman JM, Hall CB, Ritacco J, Carrion-Baralt J, Haroutunian V. Within-person across-neuropsychological test variability in very old age and in questionable dementia Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.1604  1
2009 Beeri MS, Schmeidler J, Haroutunian V, West R, Ostad D, Grossman HT, Rosendorff C, Silverman JM. Better cognitive performance associated with worse cardiac functioning suggests antagonistic pleiotropy in very elderly subjects. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 17: 911-2. PMID 19910880 DOI: 10.1097/Jgp.0B013E3181Ad4D2F  1
2009 Katsel P, Tan W, Haroutunian V. Gain in brain immunity in the oldest-old differentiates cognitively normal from demented individuals. Plos One. 4: e7642. PMID 19865478 DOI: 10.1371/Journal.Pone.0007642  1
2009 Beeri MS, Ravona-Springer R, Silverman JM, Haroutunian V. The effects of cardiovascular risk factors on cognitive compromise. Dialogues in Clinical Neuroscience. 11: 201-12. PMID 19585955  1
2009 Haroutunian V, Hoffman LB, Beeri MS. Is there a neuropathology difference between mild cognitive impairment and dementia? Dialogues in Clinical Neuroscience. 11: 171-9. PMID 19585952  1
2009 Guerrero-Berroa E, Luo X, Schmeidler J, Rapp MA, Dahlman K, Grossman HT, Haroutunian V, Beeri MS. The MMSE orientation for time domain is a strong predictor of subsequent cognitive decline in the elderly. International Journal of Geriatric Psychiatry. 24: 1429-37. PMID 19382130 DOI: 10.1002/Gps.2282  1
2009 Libow LS, Frisina PG, Haroutunian V, Perl DP, Purohit DP. Parkinson's disease dementia: a diminished role for the Lewy body. Parkinsonism & Related Disorders. 15: 572-5. PMID 19346154 DOI: 10.1016/J.Parkreldis.2009.02.003  1
2009 Kajiwara Y, Akram A, Katsel P, Haroutunian V, Schmeidler J, Beecham G, Haines JL, Pericak-Vance MA, Buxbaum JD. FE65 binds Teashirt, inhibiting expression of the primate-specific caspase-4. Plos One. 4: e5071. PMID 19343227 DOI: 10.1371/Journal.Pone.0005071  1
2009 Qin W, Haroutunian V, Katsel P, Cardozo CP, Ho L, Buxbaum JD, Pasinetti GM. PGC-1alpha expression decreases in the Alzheimer disease brain as a function of dementia. Archives of Neurology. 66: 352-61. PMID 19273754 DOI: 10.1001/Archneurol.2008.588  1
2009 Hoffman LB, Schmeidler J, Lesser GT, Beeri MS, Purohit DP, Grossman HT, Haroutunian V. Less Alzheimer disease neuropathology in medicated hypertensive than nonhypertensive persons. Neurology. 72: 1720-6. PMID 19228583 DOI: 10.1212/01.Wnl.0000345881.82856.D5  1
2009 Amadio M, Pascale A, Wang J, Ho L, Quattrone A, Gandy S, Haroutunian V, Racchi M, Pasinetti GM. nELAV proteins alteration in Alzheimer's disease brain: a novel putative target for amyloid-beta reverberating on AbetaPP processing. Journal of Alzheimer's Disease : Jad. 16: 409-19. PMID 19221430 DOI: 10.3233/Jad-2009-0967  1
2009 Bauer DE, Haroutunian V, McCullumsmith RE, Meador-Woodruff JH. Expression of four housekeeping proteins in elderly patients with schizophrenia. Journal of Neural Transmission (Vienna, Austria : 1996). 116: 487-91. PMID 19139805 DOI: 10.1007/S00702-008-0143-3  1
2009 Lesser GT, Haroutunian V, Purohit DP, Schnaider Beeri M, Schmeidler J, Honkanen L, Neufeld R, Libow LS. Serum lipids are related to Alzheimer's pathology in nursing home residents. Dementia and Geriatric Cognitive Disorders. 27: 42-9. PMID 19129700 DOI: 10.1159/000189268  1
2009 Frisina PG, Haroutunian V, Libow LS. The neuropathological basis for depression in Parkinson's disease. Parkinsonism & Related Disorders. 15: 144-8. PMID 18571456 DOI: 10.1016/J.Parkreldis.2008.04.038  1
2009 Beeri MS, Rapp M, Schmeidler J, Reichenberg A, Purohit DP, Perl DP, Grossman HT, Prohovnik I, Haroutunian V, Silverman JM. Number of children is associated with neuropathology of Alzheimer's disease in women. Neurobiology of Aging. 30: 1184-91. PMID 18079025 DOI: 10.1016/J.Neurobiolaging.2007.11.011  1
2009 Haroutunian V, Katsel P, Schmeidler J. Transcriptional vulnerability of brain regions in Alzheimer's disease and dementia. Neurobiology of Aging. 30: 561-73. PMID 17845826 DOI: 10.1016/J.Neurobiolaging.2007.07.021  1
2009 Rapp MA, Haroutunian V, Heinz A. FC05-03 Altered levels of neurotrophic factors in alzheimer's disease patients with a lifetimne history of depression European Psychiatry. 24: 1-1. DOI: 10.1016/S0924-9338(09)70548-6  1
2009 Naj AC, Beecham GW, Slifer MA, Martin ER, Gallins PJ, Konidari I, Whitehead PL, Cai G, Kajiwara Y, Haroutunian V, Gwirtsman HE, Gilbert JR, Haines JL, Buxbaum JD, Pericak-Vance MA. Genome-wide association study validates associations in APOE, VDR, SORL1, WWC1, and ELAVL4 and identifies novel candidate genes for late-onset Alzheimer's disease Alzheimers & Dementia. 5. DOI: 10.1016/J.Jalz.2009.05.519  1
2009 Beecham GW, Naj AC, Cai G, Kajiwara Y, Haroutunian V, Konidari I, Gallins P, Whitehead P, Gilbert JR, Slifer MA, Gwirstman H, Martin ER, Buxbaum J, Haines JL, Pericak-Vance MA. GRB-associated binding protein 2 (GAB2) interacts with APOE to alter risk of late-onset Alzheimer's disease Alzheimers & Dementia. 5: 111. DOI: 10.1016/J.Jalz.2009.05.348  1
2009 Slifer MA, Naj A, Beecham G, Martin E, Konidari I, Whitehead P, Gallins P, Cai G, Kajiwara Y, Haroutunian V, Vance J, Haines J, Buxbaum J, Pericak-Vance M. ELAVL4 locus confirmed in depression of Alzheimer's disease Alzheimers & Dementia. 5: 468. DOI: 10.1016/J.Jalz.2009.04.793  1
2008 Rao MV, Mohan PS, Peterhoff CM, Yang DS, Schmidt SD, Stavrides PH, Campbell J, Chen Y, Jiang Y, Paskevich PA, Cataldo AM, Haroutunian V, Nixon RA. Marked calpastatin (CAST) depletion in Alzheimer's disease accelerates cytoskeleton disruption and neurodegeneration: neuroprotection by CAST overexpression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 12241-54. PMID 19020018 DOI: 10.1523/Jneurosci.4119-08.2008  1
2008 Alelú-Paz R, Iturrieta-Zuazo I, Byne W, Haroutunian V, García-Villanueva M, Rábano A, García-Amado M, Prensa L, Giménez-Amaya JM. A new antigen retrieval technique for human brain tissue. Plos One. 3: e3378. PMID 18852880 DOI: 10.1371/Journal.Pone.0003378  1
2008 Haroutunian V, Schnaider-Beeri M, Schmeidler J, Wysocki M, Purohit DP, Perl DP, Libow LS, Lesser GT, Maroukian M, Grossman HT. Role of the neuropathology of Alzheimer disease in dementia in the oldest-old. Archives of Neurology. 65: 1211-7. PMID 18779425 DOI: 10.1001/Archneur.65.9.1211  1
2008 Beeri MS, Schmeidler J, Silverman JM, Gandy S, Wysocki M, Hannigan CM, Purohit DP, Lesser G, Grossman HT, Haroutunian V. Insulin in combination with other diabetes medication is associated with less Alzheimer neuropathology. Neurology. 71: 750-7. PMID 18765651 DOI: 10.1212/01.Wnl.0000324925.95210.6D  1
2008 Steffek AE, McCullumsmith RE, Haroutunian V, Meador-Woodruff JH. Cortical expression of glial fibrillary acidic protein and glutamine synthetase is decreased in schizophrenia. Schizophrenia Research. 103: 71-82. PMID 18562176 DOI: 10.1016/J.Schres.2008.04.032  1
2008 Elder GA, Ragnauth A, Dorr N, Franciosi S, Schmeidler J, Haroutunian V, Buxbaum JD. Increased locomotor activity in mice lacking the low-density lipoprotein receptor. Behavioural Brain Research. 191: 256-65. PMID 18466986 DOI: 10.1016/J.Bbr.2008.03.036  1
2008 Dracheva S, Byne W, Chin B, Haroutunian V. Ionotropic glutamate receptor mRNA expression in the human thalamus: absence of change in schizophrenia. Brain Research. 1214: 23-34. PMID 18462708 DOI: 10.1016/J.Brainres.2008.03.039  1
2008 Schnaider Beeri M, Silverman JM, Schmeidler J, Wysocki M, Grossman HZ, Purohit DP, Perl DP, Haroutunian V. Clinical dementia rating performed several years prior to death predicts regional Alzheimer's neuropathology. Dementia and Geriatric Cognitive Disorders. 25: 392-8. PMID 18367838 DOI: 10.1159/000122586  1
2008 Katsel P, Davis KL, Li C, Tan W, Greenstein E, Kleiner Hoffman LB, Haroutunian V. Abnormal indices of cell cycle activity in schizophrenia and their potential association with oligodendrocytes. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 2993-3009. PMID 18322470 DOI: 10.1038/Npp.2008.19  1
2008 Dracheva S, Chin B, Haroutunian V. Altered serotonin 2C receptor RNA splicing in suicide: association with editing. Neuroreport. 19: 379-82. PMID 18303585 DOI: 10.1097/Wnr.0B013E3282F556D2  1
2008 Rapp MA, Schnaider-Beeri M, Purohit DP, Perl DP, Haroutunian V, Sano M. Increased neurofibrillary tangles in patients with Alzheimer disease with comorbid depression. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 16: 168-74. PMID 18239198 DOI: 10.1097/Jgp.0B013E31816029Ec  1
2008 Oni-Orisan A, Kristiansen LV, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE. Altered vesicular glutamate transporter expression in the anterior cingulate cortex in schizophrenia. Biological Psychiatry. 63: 766-75. PMID 18155679 DOI: 10.1016/J.Biopsych.2007.10.020  1
2008 Byne W, Dracheva S, Chin B, Schmeidler JM, Davis KL, Haroutunian V. Schizophrenia and sex associated differences in the expression of neuronal and oligodendrocyte-specific genes in individual thalamic nuclei. Schizophrenia Research. 98: 118-28. PMID 18029146 DOI: 10.1016/J.Schres.2007.09.034  1
2008 Lauriat TL, Shiue L, Haroutunian V, Verbitsky M, Ares M, Ospina L, McInnes LA. Developmental expression profile of quaking, a candidate gene for schizophrenia, and its target genes in human prefrontal cortex and hippocampus shows regional specificity. Journal of Neuroscience Research. 86: 785-96. PMID 17918747 DOI: 10.1002/Jnr.21534  1
2008 Dracheva S, Patel N, Woo DA, Marcus SM, Siever LJ, Haroutunian V. Increased serotonin 2C receptor mRNA editing: a possible risk factor for suicide. Molecular Psychiatry. 13: 1001-10. PMID 17848916 DOI: 10.1038/Sj.Mp.4002081  1
2008 Baker DA, Madayag A, Kristiansen LV, Meador-Woodruff JH, Haroutunian V, Raju I. Contribution of cystine-glutamate antiporters to the psychotomimetic effects of phencyclidine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 1760-72. PMID 17728701 DOI: 10.1038/Sj.Npp.1301532  1
2008 Akram A, Christoffel D, Rocher AB, Bouras C, Kövari E, Perl DP, Morrison JH, Herrmann FR, Haroutunian V, Giannakopoulos P, Hof PR. Stereologic estimates of total spinophilin-immunoreactive spine number in area 9 and the CA1 field: relationship with the progression of Alzheimer's disease. Neurobiology of Aging. 29: 1296-307. PMID 17420070 DOI: 10.1016/J.Neurobiolaging.2007.03.007  1
2007 Haroutunian V, Pickett J. Autism brain tissue banking. Brain Pathology (Zurich, Switzerland). 17: 412-21. PMID 17919127 DOI: 10.1111/J.1750-3639.2007.00097.X  1
2007 Haroutunian V, Davis KL. Introduction to the special section: Myelin and oligodendrocyte abnormalities in schizophrenia. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 10: 499-502. PMID 17583597 DOI: 10.1017/S1461145706007449  1
2007 Elder GA, Cho JY, English DF, Franciosi S, Schmeidler J, Sosa MA, Gasperi RD, Fisher EA, Mathews PM, Haroutunian V, Buxbaum JD. Elevated plasma cholesterol does not affect brain Abeta in mice lacking the low-density lipoprotein receptor. Journal of Neurochemistry. 102: 1220-31. PMID 17472705 DOI: 10.1111/J.1471-4159.2007.04614.X  1
2007 Katsel P, Li C, Haroutunian V. Gene expression alterations in the sphingolipid metabolism pathways during progression of dementia and Alzheimer's disease: a shift toward ceramide accumulation at the earliest recognizable stages of Alzheimer's disease? Neurochemical Research. 32: 845-56. PMID 17342407 DOI: 10.1007/S11064-007-9297-X  1
2007 Haroutunian V, Katsel P, Dracheva S, Stewart DG, Davis KL. Variations in oligodendrocyte-related gene expression across multiple cortical regions: implications for the pathophysiology of schizophrenia. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 10: 565-73. PMID 17291370 DOI: 10.1017/S1461145706007310  1
2007 Hulette CM, Welsh-Bohmer K. Coronary artery disease is associated with Alzheimer disease neuropathology in APOE4 carriers. Neurology. 68: 471; author reply 47. PMID 17283328 DOI: 10.1212/01.wnl.0000256286.78188.dd  1
2007 Greenstein RJ, Su L, Haroutunian V, Shahidi A, Brown ST. On the action of methotrexate and 6-mercaptopurine on M. avium subspecies paratuberculosis. Plos One. 2: e161. PMID 17252054 DOI: 10.1371/Journal.Pone.0000161  1
2007 McCullumsmith RE, Gupta D, Beneyto M, Kreger E, Haroutunian V, Davis KL, Meador-Woodruff JH. Expression of transcripts for myelination-related genes in the anterior cingulate cortex in schizophrenia. Schizophrenia Research. 90: 15-27. PMID 17223013 DOI: 10.1016/J.Schres.2006.11.017  1
2007 Byne W, Fernandes J, Haroutunian V, Huacon D, Kidkardnee S, Kim J, Tatusov A, Thakur U, Yiannoulos G. Reduction of right medial pulvinar volume and neuron number in schizophrenia. Schizophrenia Research. 90: 71-5. PMID 17141474 DOI: 10.1016/J.Schres.2006.10.006  1
2007 Yakovleva T, Marinova Z, Kuzmin A, Seidah NG, Haroutunian V, Terenius L, Bakalkin G. Dysregulation of dynorphins in Alzheimer disease. Neurobiology of Aging. 28: 1700-8. PMID 16914231 DOI: 10.1016/J.Neurobiolaging.2006.07.002  1
2007 Gill SK, Ishak M, Dobransky T, Haroutunian V, Davis KL, Rylett RJ. 82-kDa choline acetyltransferase is in nuclei of cholinergic neurons in human CNS and altered in aging and Alzheimer disease. Neurobiology of Aging. 28: 1028-40. PMID 16797789 DOI: 10.1016/J.Neurobiolaging.2006.05.011  1
2007 Zhao Z, Xiang Z, Haroutunian V, Buxbaum JD, Stetka B, Pasinetti GM. Insulin degrading enzyme activity selectively decreases in the hippocampal formation of cases at high risk to develop Alzheimer's disease. Neurobiology of Aging. 28: 824-30. PMID 16769157 DOI: 10.1016/J.Neurobiolaging.2006.05.001  1
2007 Haroutunian V, Davies P, Vianna C, Buxbaum JD, Purohit DP. Tau protein abnormalities associated with the progression of alzheimer disease type dementia. Neurobiology of Aging. 28: 1-7. PMID 16343696 DOI: 10.1016/J.Neurobiolaging.2005.11.001  1
2007 London E, Haroutunian V. Symposium: Neurobiology of autism - Introduction Brain Pathology. 17: 407. DOI: 10.1111/J.1750-3639.2007.00106.X  1
2006 Haroutunian V, Katsel P, Dracheva S, Davis KL. The human homolog of the QKI gene affected in the severe dysmyelination "quaking" mouse phenotype: downregulated in multiple brain regions in schizophrenia. The American Journal of Psychiatry. 163: 1834-7. PMID 17012699 DOI: 10.1176/Ajp.2006.163.10.1834  1
2006 Lauriat TL, Dracheva S, Kremerskothen J, Duning K, Haroutunian V, Buxbaum JD, Hyde TM, Kleinman JE, McInnes LA. Characterization of KIAA0513, a novel signaling molecule that interacts with modulators of neuroplasticity, apoptosis, and the cytoskeleton. Brain Research. 1121: 1-11. PMID 17010949 DOI: 10.1016/J.Brainres.2006.08.099  1
2006 Georgieva L, Moskvina V, Peirce T, Norton N, Bray NJ, Jones L, Holmans P, Macgregor S, Zammit S, Wilkinson J, Williams H, Nikolov I, Williams N, Ivanov D, Davis KL, ... Haroutunian V, et al. Convergent evidence that oligodendrocyte lineage transcription factor 2 (OLIG2) and interacting genes influence susceptibility to schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 103: 12469-74. PMID 16891421 DOI: 10.1073/Pnas.0603029103  1
2006 Steffek AE, Haroutunian V, Meador-Woodruff JH. Serine racemase protein expression in cortex and hippocampus in schizophrenia. Neuroreport. 17: 1181-5. PMID 16837850 DOI: 10.1097/01.Wnr.0000230512.01339.72  1
2006 Religa D, Strozyk D, Cherny RA, Volitakis I, Haroutunian V, Winblad B, Naslund J, Bush AI. Elevated cortical zinc in Alzheimer disease. Neurology. 67: 69-75. PMID 16832080 DOI: 10.1212/01.Wnl.0000223644.08653.B5  1
2006 Baracskay KL, Haroutunian V, Meador-Woodruff JH. Dopamine receptor signaling molecules are altered in elderly schizophrenic cortex. Synapse (New York, N.Y.). 60: 271-9. PMID 16786528 DOI: 10.1002/Syn.20292  1
2006 Clinton SM, Haroutunian V, Meador-Woodruff JH. Up-regulation of NMDA receptor subunit and post-synaptic density protein expression in the thalamus of elderly patients with schizophrenia. Journal of Neurochemistry. 98: 1114-25. PMID 16762023 DOI: 10.1111/J.1471-4159.2006.03954.X  1
2006 Byne W, Kidkardnee S, Tatusov A, Yiannoulos G, Buchsbaum MS, Haroutunian V. Schizophrenia-associated reduction of neuronal and oligodendrocyte numbers in the anterior principal thalamic nucleus. Schizophrenia Research. 85: 245-53. PMID 16730162 DOI: 10.1016/J.Schres.2006.03.029  1
2006 Kristiansen LV, Beneyto M, Haroutunian V, Meador-Woodruff JH. Changes in NMDA receptor subunits and interacting PSD proteins in dorsolateral prefrontal and anterior cingulate cortex indicate abnormal regional expression in schizophrenia. Molecular Psychiatry. 11: 737-47, 705. PMID 16702973 DOI: 10.1038/Sj.Mp.4001844  1
2006 Beeri MS, Rapp M, Silverman JM, Schmeidler J, Grossman HT, Fallon JT, Purohit DP, Perl DP, Siddiqui A, Lesser G, Rosendorff C, Haroutunian V. Coronary artery disease is associated with Alzheimer disease neuropathology in APOE4 carriers. Neurology. 66: 1399-404. PMID 16682673 DOI: 10.1212/01.Wnl.0000210447.19748.0B  1
2006 Zhao Z, Ksiezak-Reding H, Riggio S, Haroutunian V, Pasinetti GM. Insulin receptor deficits in schizophrenia and in cellular and animal models of insulin receptor dysfunction. Schizophrenia Research. 84: 1-14. PMID 16581231 DOI: 10.1016/J.Schres.2006.02.009  1
2006 Huerta I, McCullumsmith RE, Haroutunian V, Giménez-Amaya JM, Meador-Woodruff JH. Expression of excitatory amino acid transporter interacting protein transcripts in the thalamus in schizophrenia. Synapse (New York, N.Y.). 59: 394-402. PMID 16485262 DOI: 10.1002/Syn.20250  1
2006 Rapp MA, Schnaider-Beeri M, Grossman HT, Sano M, Perl DP, Purohit DP, Gorman JM, Haroutunian V. Increased hippocampal plaques and tangles in patients with Alzheimer disease with a lifetime history of major depression. Archives of General Psychiatry. 63: 161-7. PMID 16461859 DOI: 10.1001/Archpsyc.63.2.161  1
2006 Xiang Z, Haroutunian V, Ho L, Purohit D, Pasinetti GM. Microglia activation in the brain as inflammatory biomarker of Alzheimer's disease neuropathology and clinical dementia. Disease Markers. 22: 95-102. PMID 16410654 DOI: 10.1155/2006/276239  1
2006 Prohovnik I, Perl DP, Davis KL, Libow L, Lesser G, Haroutunian V. Dissociation of neuropathology from severity of dementia in late-onset Alzheimer disease. Neurology. 66: 49-55. PMID 16401845 DOI: 10.1212/01.Wnl.0000191298.68045.50  1
2006 Peirce TR, Bray NJ, Williams NM, Norton N, Moskvina V, Preece A, Haroutunian V, Buxbaum JD, Owen MJ, O'Donovan MC. Convergent evidence for 2',3'-cyclic nucleotide 3'-phosphodiesterase as a possible susceptibility gene for schizophrenia. Archives of General Psychiatry. 63: 18-24. PMID 16389193 DOI: 10.1001/Archpsyc.63.1.18  1
2006 Lauriat TL, Dracheva S, Chin B, Schmeidler J, McInnes LA, Haroutunian V. Quantitative analysis of glutamate transporter mRNA expression in prefrontal and primary visual cortex in normal and schizophrenic brain. Neuroscience. 137: 843-51. PMID 16297566 DOI: 10.1016/J.Neuroscience.2005.10.003  1
2006 Dracheva S, Davis KL, Chin B, Woo DA, Schmeidler J, Haroutunian V. Myelin-associated mRNA and protein expression deficits in the anterior cingulate cortex and hippocampus in elderly schizophrenia patients. Neurobiology of Disease. 21: 531-40. PMID 16213148 DOI: 10.1016/J.Nbd.2005.08.012  1
2006 Kristiansen LV, Beneyto M, Haroutunian V, Meador-Woodruff JH. Altered NMDA receptor expression in schizophrenia Molecular Psychiatry. 11: 705. DOI: 10.1038/Sj.Mp.4001871  1
2006 Silverman JM, Lesser GT, Beeri MS, Rapp MA, Libow LS, Purohit DP, Tarshish C, Haroutunian V. P1-204: Serum total and LDL cholesterol are associated with Alzheimer’s disease neuropathological diagnosis in the very old Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.581  1
2005 Rosoklija G, Keilp JG, Toomayan G, Mancevski B, Haroutunian V, Liu D, Malespina D, Hays AP, Sadiq S, Latov N, Dwork AJ. Altered subicular MAP2 immunoreactivity in schizophrenia. Prilozi / Makedonska Akademija Na Naukite I Umetnostite, Oddelenie Za Bioloå¡Ki I Medicinski Nauki = Contributions / Macedonian Academy of Sciences and Arts, Section of Biological and Medical Sciences. 26: 13-34. PMID 16400226  1
2005 Clinton SM, Ibrahim HM, Frey KA, Davis KL, Haroutunian V, Meador-Woodruff JH. Dopaminergic abnormalities in select thalamic nuclei in schizophrenia: involvement of the intracellular signal integrating proteins calcyon and spinophilin. The American Journal of Psychiatry. 162: 1859-71. PMID 16199832 DOI: 10.1176/Appi.Ajp.162.10.1859  1
2005 Zhao Z, Ho L, Wang J, Qin W, Festa ED, Mobbs C, Hof P, Rocher A, Masur S, Haroutunian V, Pasinetti GM. Connective tissue growth factor (CTGF) expression in the brain is a downstream effector of insulin resistance- associated promotion of Alzheimer's disease beta-amyloid neuropathology. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 2081-2. PMID 16186174 DOI: 10.1096/Fj.05-4359Fje  1
2005 Katsel P, Davis KL, Haroutunian V. Variations in myelin and oligodendrocyte-related gene expression across multiple brain regions in schizophrenia: a gene ontology study. Schizophrenia Research. 79: 157-73. PMID 16139990 DOI: 10.1016/J.Schres.2005.06.007  1
2005 Rapp MA, Schnaider Beeri M, Schmeidler J, Sano M, Silverman JM, Haroutunian V. Relationship of neuropsychological performance to functional status in nursing home residents and community-dwelling older adults. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 13: 450-9. PMID 15956264 DOI: 10.1176/appi.ajgp.13.6.450  1
2005 Gupta DS, McCullumsmith RE, Beneyto M, Haroutunian V, Davis KL, Meador-Woodruff JH. Metabotropic glutamate receptor protein expression in the prefrontal cortex and striatum in schizophrenia. Synapse (New York, N.Y.). 57: 123-31. PMID 15945063 DOI: 10.1002/Syn.20164  1
2005 Beeri MS, Silverman JM, Davis KL, Marin D, Grossman HZ, Schmeidler J, Purohit DP, Perl DP, Davidson M, Mohs RC, Haroutunian V. Type 2 diabetes is negatively associated with Alzheimer's disease neuropathology. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 60: 471-5. PMID 15933386 DOI: 10.1093/Gerona/60.4.471  1
2005 Katsel P, Davis KL, Gorman JM, Haroutunian V. Variations in differential gene expression patterns across multiple brain regions in schizophrenia. Schizophrenia Research. 77: 241-52. PMID 15923110 DOI: 10.1016/J.Schres.2005.03.020  1
2005 Bubber P, Haroutunian V, Fisch G, Blass JP, Gibson GE. Mitochondrial abnormalities in Alzheimer brain: mechanistic implications. Annals of Neurology. 57: 695-703. PMID 15852400 DOI: 10.1002/Ana.20474  1
2005 Rapp MA, Schnaider-Beeri M, Sano M, Silverman JM, Haroutunian V. Cross-domain variability of cognitive performance in very old nursing home residents and community dwellers: relationship to functional status. Gerontology. 51: 206-12. PMID 15832049 DOI: 10.1159/000083995  1
2005 Bruneau EG, McCullumsmith RE, Haroutunian V, Davis KL, Meador-Woodruff JH. Increased expression of glutaminase and glutamine synthetase mRNA in the thalamus in schizophrenia. Schizophrenia Research. 75: 27-34. PMID 15820321 DOI: 10.1016/J.Schres.2004.12.012  1
2005 Rapp MA, Dahlman K, Sano M, Grossman HT, Haroutunian V, Gorman JM. Neuropsychological differences between late-onset and recurrent geriatric major depression. The American Journal of Psychiatry. 162: 691-8. PMID 15800140 DOI: 10.1176/Appi.Ajp.162.4.691  1
2005 Katsel PL, Davis KL, Haroutunian V. Large-scale microarray studies of gene expression in multiple regions of the brain in schizophrenia and Alzheimer's disease. International Review of Neurobiology. 63: 41-82. PMID 15797465 DOI: 10.1016/S0074-7742(05)63003-6  1
2005 Dracheva S, McGurk SR, Haroutunian V. mRNA expression of AMPA receptors and AMPA receptor binding proteins in the cerebral cortex of elderly schizophrenics. Journal of Neuroscience Research. 79: 868-78. PMID 15696539 DOI: 10.1002/Jnr.20423  1
2005 Rapp MA, Beeri MS, Schmeidler J, Sano M, Silverman JM, Haroutunian V. Relationship of neuropsychological performance to functional status in nursing home residents and community-dwelling older adults. American Journal of Geriatric Psychiatry. 13: 450-459. DOI: 10.1097/00019442-200506000-00003  1
2004 Gordon D, Yang Y, Haynes C, Finch SJ, Mendell NR, Brown AM, Haroutunian V. Increasing power for tests of genetic association in the presence of phenotype and/or genotype error by use of double-sampling. Statistical Applications in Genetics and Molecular Biology. 3: Article26. PMID 16646805 DOI: 10.2202/1544-6115.1085  1
2004 Buckland PR, Hoogendoorn B, Guy CA, Coleman SL, Smith SK, Buxbaum JD, Haroutunian V, O'Donovan MC. A high proportion of polymorphisms in the promoters of brain expressed genes influences transcriptional activity. Biochimica Et Biophysica Acta. 1690: 238-49. PMID 15511631 DOI: 10.1016/J.Bbadis.2004.06.023  1
2004 Cataldo AM, Petanceska S, Terio NB, Peterhoff CM, Durham R, Mercken M, Mehta PD, Buxbaum J, Haroutunian V, Nixon RA. Abeta localization in abnormal endosomes: association with earliest Abeta elevations in AD and Down syndrome. Neurobiology of Aging. 25: 1263-72. PMID 15465622 DOI: 10.1016/J.Neurobiolaging.2004.02.027  1
2004 Bubber P, Tang J, Haroutunian V, Xu H, Davis KL, Blass JP, Gibson GE. Mitochondrial enzymes in schizophrenia. Journal of Molecular Neuroscience : Mn. 24: 315-21. PMID 15456945 DOI: 10.1385/Jmn:24:2:315  1
2004 Brown AM, Gordon D, Lee H, Caudy M, Hardy J, Haroutunian V, Blass JP. Association of the dihydrolipoamide dehydrogenase gene with Alzheimer's disease in an Ashkenazi Jewish population. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 131: 60-6. PMID 15389771 DOI: 10.1002/Ajmg.B.30008  1
2004 Bray NJ, Jehu L, Moskvina V, Buxbaum JD, Dracheva S, Haroutunian V, Williams J, Buckland PR, Owen MJ, O'Donovan MC. Allelic expression of APOE in human brain: effects of epsilon status and promoter haplotypes. Human Molecular Genetics. 13: 2885-92. PMID 15385439 DOI: 10.1093/Hmg/Ddh299  1
2004 Bai J, He F, Novikova SI, Undie AS, Dracheva S, Haroutunian V, Lidow MS. Abnormalities in the dopamine system in schizophrenia may lie in altered levels of dopamine receptor-interacting proteins. Biological Psychiatry. 56: 427-40. PMID 15364041 DOI: 10.1016/J.Biopsych.2004.06.022  1
2004 Wen PH, Hof PR, Chen X, Gluck K, Austin G, Younkin SG, Younkin LH, DeGasperi R, Gama Sosa MA, Robakis NK, Haroutunian V, Elder GA. The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice. Experimental Neurology. 188: 224-37. PMID 15246822 DOI: 10.1016/J.Expneurol.2004.04.002  1
2004 Dracheva S, Elhakem SL, McGurk SR, Davis KL, Haroutunian V. GAD67 and GAD65 mRNA and protein expression in cerebrocortical regions of elderly patients with schizophrenia. Journal of Neuroscience Research. 76: 581-92. PMID 15114630 DOI: 10.1002/Jnr.20122  1
2004 Brown AM, Gordon D, Lee H, Caudy M, Haroutunian V, Blass JP. Substantial linkage disequilibrium across the dihydrolipoyl succinyltransferase gene region without Alzheimer's disease association. Neurochemical Research. 29: 629-35. PMID 15038610 DOI: 10.1023/B:Nere.0000014833.54481.1D  1
2004 Mueller HT, Haroutunian V, Davis KL, Meador-Woodruff JH. Expression of the ionotropic glutamate receptor subunits and NMDA receptor-associated intracellular proteins in the substantia nigra in schizophrenia. Brain Research. Molecular Brain Research. 121: 60-9. PMID 14969737 DOI: 10.1016/J.Molbrainres.2003.11.004  1
2004 Santucci AC, Haroutunian V. p-Chloroamphetamine blocks physostigmine-induced memory enhancement in rats with unilateral nucleus basalis lesions. Pharmacology, Biochemistry, and Behavior. 77: 59-67. PMID 14724042 DOI: 10.1016/J.Pbb.2003.09.022  1
2004 Clinton SM, Abelson S, Haroutunian V, Davis K, Meador-Woodruff JH. Neurofilament subunit protein abnormalities in the thalamus in schizophrenia Thalamus and Related Systems. 2: 265-272. DOI: 10.1016/J.Tharel.2003.11.001  1
2003 Dracheva S, Elhakem SL, Marcus SM, Siever LJ, McGurk SR, Haroutunian V. RNA editing and alternative splicing of human serotonin 2C receptor in schizophrenia. Journal of Neurochemistry. 87: 1402-12. PMID 14713296 DOI: 10.1046/J.1471-4159.2003.02115.X  1
2003 Martin-Ruiz CM, Haroutunian VH, Long P, Young AH, Davis KL, Perry EK, Court JA. Dementia rating and nicotinic receptor expression in the prefrontal cortex in schizophrenia. Biological Psychiatry. 54: 1222-33. PMID 14643090 DOI: 10.1016/S0006-3223(03)00348-2  1
2003 Halks-Miller M, Schroeder ML, Haroutunian V, Moenning U, Rossi M, Achim C, Purohit D, Mahmoudi M, Horuk R. CCR1 is an early and specific marker of Alzheimer's disease. Annals of Neurology. 54: 638-46. PMID 14595653 DOI: 10.1002/Ana.10733  1
2003 Causevic M, Ramoz N, Haroutunian V, Davis KL, Buxbaum JD. Lack of association between the levels of the low-density lipoprotein receptor-related protein (LRP) and either Alzheimer dementia or LRP exon 3 genotype. Journal of Neuropathology and Experimental Neurology. 62: 999-1005. PMID 14575236 DOI: 10.1093/Jnen/62.10.999  1
2003 Lilliehook C, Bozdagi O, Yao J, Gomez-Ramirez M, Zaidi NF, Wasco W, Gandy S, Santucci AC, Haroutunian V, Huntley GW, Buxbaum JD. Altered Abeta formation and long-term potentiation in a calsenilin knock-out. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9097-106. PMID 14534243  1
2003 Davis KL, Haroutunian V. Global expression-profiling studies and oligodendrocyte dysfunction in schizophrenia and bipolar disorder. Lancet. 362: 758. PMID 13678867 DOI: 10.1016/S0140-6736(03)14297-3  1
2003 Polesskaya OO, Haroutunian V, Davis KL, Hernandez I, Sokolov BP. Novel putative nonprotein-coding RNA gene from 11q14 displays decreased expression in brains of patients with schizophrenia. Journal of Neuroscience Research. 74: 111-22. PMID 13130513 DOI: 10.1002/Jnr.10752  1
2003 Hof PR, Haroutunian V, Friedrich VL, Byne W, Buitron C, Perl DP, Davis KL. Loss and altered spatial distribution of oligodendrocytes in the superior frontal gyrus in schizophrenia. Biological Psychiatry. 53: 1075-85. PMID 12814859 DOI: 10.1016/S0006-3223(03)00237-3  1
2003 Clinton SM, Haroutunian V, Davis KL, Meador-Woodruff JH. Altered transcript expression of NMDA receptor-associated postsynaptic proteins in the thalamus of subjects with schizophrenia. The American Journal of Psychiatry. 160: 1100-9. PMID 12777268 DOI: 10.1176/Appi.Ajp.160.6.1100  1
2003 Davis KL, Stewart DG, Friedman JI, Buchsbaum M, Harvey PD, Hof PR, Buxbaum J, Haroutunian V. White matter changes in schizophrenia: evidence for myelin-related dysfunction. Archives of General Psychiatry. 60: 443-56. PMID 12742865 DOI: 10.1001/Archpsyc.60.5.443  1
2003 Religa D, Laudon H, Styczynska M, Winblad B, Näslund J, Haroutunian V. Amyloid beta pathology in Alzheimer's disease and schizophrenia. The American Journal of Psychiatry. 160: 867-72. PMID 12727689 DOI: 10.1176/Appi.Ajp.160.5.867  1
2003 Serby M, Brickman AM, Haroutunian V, Purohit DP, Marin D, Lantz M, Mohs RC, Davis KL. Cognitive burden and excess Lewy-body pathology in the Lewy-body variant of Alzheimer disease. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 11: 371-4. PMID 12724118 DOI: 10.1097/00019442-200305000-00016  1
2003 Pompl PN, Yemul S, Xiang Z, Ho L, Haroutunian V, Purohit D, Mohs R, Pasinetti GM. Caspase gene expression in the brain as a function of the clinical progression of Alzheimer disease. Archives of Neurology. 60: 369-76. PMID 12633148 DOI: 10.1001/Archneur.60.3.369  1
2003 Lilliehook C, Bozdagi O, Yao J, Gomez-Ramirez M, Zaidi NF, Wasco W, Gandy S, Santucci AC, Haroutunian V, Huntley GW, Buxbaum JD. Altered Aβ Formation and Long-Term Potentiation in a Calsenilin Knock-Out The Journal of Neuroscience. 23: 9097-9106. DOI: 10.1523/Jneurosci.23-27-09097.2003  1
2003 Haroutunian V, Dracheva S, Davis KL. Neurobiology of glutamatergic abnormalities in schizophrenia Clinical Neuroscience Research. 3: 67-76. DOI: 10.1016/S1566-2772(03)00020-3  1
2003 Davis K, Stewart D, Friedman J, Buchsbaum M, Harvey P, Hof P, Buxbaum J, Haroutunian V. S.18.01 Schizophrenia: Effects of aging on cognition European Neuropsychopharmacology. 13. DOI: 10.1016/S0924-977X(03)91669-5  1
2002 Hof PR, Haroutunian V, Copland C, Davis KL, Buxbaum JD. Molecular and cellular evidence for an oligodendrocyte abnormality in schizophrenia. Neurochemical Research. 27: 1193-200. PMID 12462417 DOI: 10.1023/A:1020981510759  1
2002 Utsuki T, Shoaib M, Holloway HW, Ingram DK, Wallace WC, Haroutunian V, Sambamurti K, Lahiri DK, Greig NH. Nicotine lowers the secretion of the Alzheimer's amyloid beta-protein precursor that contains amyloid beta-peptide in rat. Journal of Alzheimer's Disease : Jad. 4: 405-15. PMID 12446972 DOI: 10.3233/Jad-2002-4507  1
2002 Haroutunian V, Davis KL. Issues and perspectives on brain tissue banking. Current Psychiatry Reports. 4: 233-4. PMID 12126590 DOI: 10.1007/S11920-996-0039-6  1
2002 Gluck MR, Thomas RG, Davis KL, Haroutunian V. Implications for altered glutamate and GABA metabolism in the dorsolateral prefrontal cortex of aged schizophrenic patients. The American Journal of Psychiatry. 159: 1165-73. PMID 12091195 DOI: 10.1176/Appi.Ajp.159.7.1165  1
2002 Byne W, Buchsbaum MS, Mattiace LA, Hazlett EA, Kemether E, Elhakem SL, Purohit DP, Haroutunian V, Jones L. Postmortem assessment of thalamic nuclear volumes in subjects with schizophrenia. The American Journal of Psychiatry. 159: 59-65. PMID 11772691 DOI: 10.1176/Appi.Ajp.159.1.59  1
2001 Parvathy S, Davies P, Haroutunian V, Purohit DP, Davis KL, Mohs RC, Park H, Moran TM, Chan JY, Buxbaum JD. Correlation between Abetax-40-, Abetax-42-, and Abetax-43-containing amyloid plaques and cognitive decline. Archives of Neurology. 58: 2025-32. PMID 11735776 DOI: 10.1001/Archneur.58.12.2025  1
2001 Smith RE, Haroutunian V, Davis KL, Meador-Woodruff JH. Vesicular glutamate transporter transcript expression in the thalamus in schizophrenia. Neuroreport. 12: 2885-7. PMID 11588596 DOI: 10.1097/00001756-200109170-00026  1
2001 Dracheva S, Marras SA, Elhakem SL, Kramer FR, Davis KL, Haroutunian V. N-methyl-D-aspartic acid receptor expression in the dorsolateral prefrontal cortex of elderly patients with schizophrenia. The American Journal of Psychiatry. 158: 1400-10. PMID 11532724 DOI: 10.1176/Appi.Ajp.158.9.1400  1
2001 Smith RE, Haroutunian V, Davis KL, Meador-Woodruff JH. Expression of excitatory amino acid transporter transcripts in the thalamus of subjects with schizophrenia. The American Journal of Psychiatry. 158: 1393-9. PMID 11532723 DOI: 10.1176/Appi.Ajp.158.9.1393  1
2001 Dracheva S, Haroutunian V. Locomotor behavior of dopamine D1 receptor transgenic/D2 receptor deficient hybrid mice. Brain Research. 905: 142-51. PMID 11423089 DOI: 10.1016/S0006-8993(01)02522-7  1
2001 Brown AM, Sheu RK, Mohs R, Haroutunian V, Blass JP. Correlation of the clinical severity of Alzheimer's disease with an aberration in mitochondrial DNA (mtDNA). Journal of Molecular Neuroscience : Mn. 16: 41-8. PMID 11345519 DOI: 10.1385/Jmn:16:1:41  1
2001 Hakak Y, Walker JR, Li C, Wong WH, Davis KL, Buxbaum JD, Haroutunian V, Fienberg AA. Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 98: 4746-51. PMID 11296301 DOI: 10.1073/Pnas.081071198  1
2001 Meador-Woodruff JH, Davis KL, Haroutunian V. Abnormal kainate receptor expression in prefrontal cortex in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 24: 545-52. PMID 11282254 DOI: 10.1016/S0893-133X(00)00189-5  1
2001 Ho L, Purohit D, Haroutunian V, Luterman JD, Willis F, Naslund J, Buxbaum JD, Mohs RC, Aisen PS, Pasinetti GM. Neuronal cyclooxygenase 2 expression in the hippocampal formation as a function of the clinical progression of Alzheimer disease. Archives of Neurology. 58: 487-92. PMID 11255454 DOI: 10.1001/Archneur.58.3.487  1
2001 Lesser G, Kandiah K, Libow LS, Likourezos A, Breuer B, Marin D, Mohs R, Haroutunian V, Neufeld R. Elevated serum total and LDL cholesterol in very old patients with Alzheimer's disease. Dementia and Geriatric Cognitive Disorders. 12: 138-45. PMID 11173887 DOI: 10.1159/000051248  1
2001 Ho L, Guo Y, Spielman L, Petrescu O, Haroutunian V, Purohit D, Czernik A, Yemul S, Aisen PS, Mohs R, Pasinetti GM. Altered expression of a-type but not b-type synapsin isoform in the brain of patients at high risk for Alzheimer's disease assessed by DNA microarray technique. Neuroscience Letters. 298: 191-4. PMID 11165439 DOI: 10.1016/S0304-3940(00)01753-5  1
2000 Ibrahim HM, Hogg AJ, Healy DJ, Haroutunian V, Davis KL, Meador-Woodruff JH. Ionotropic glutamate receptor binding and subunit mRNA expression in thalamic nuclei in schizophrenia. The American Journal of Psychiatry. 157: 1811-23. PMID 11058479 DOI: 10.1176/Appi.Ajp.157.11.1811  1
2000 Gibson GE, Haroutunian V, Zhang H, Park LC, Shi Q, Lesser M, Mohs RC, Sheu RK, Blass JP. Mitochondrial damage in Alzheimer's disease varies with apolipoprotein E genotype. Annals of Neurology. 48: 297-303. PMID 10976635 DOI: 10.1002/1531-8249(200009)48:3<297::Aid-Ana3>3.0.Co;2-Z  1
2000 Luterman JD, Haroutunian V, Yemul S, Ho L, Purohit D, Aisen PS, Mohs R, Pasinetti GM. Cytokine gene expression as a function of the clinical progression of Alzheimer disease dementia. Archives of Neurology. 57: 1153-60. PMID 10927795 DOI: 10.1001/Archneur.57.8.1153  1
2000 Haroutunian V, Serby M, Purohit DP, Perl DP, Marin D, Lantz M, Mohs RC, Davis KL. Contribution of Lewy body inclusions to dementia in patients with and without Alzheimer disease neuropathological conditions. Archives of Neurology. 57: 1145-50. PMID 10927794 DOI: 10.1001/Archneur.57.8.1145  1
2000 Sokolov BP, Tcherepanov AA, Haroutunian V, Davis KL. Levels of mRNAs encoding synaptic vesicle and synaptic plasma membrane proteins in the temporal cortex of elderly schizophrenic patients. Biological Psychiatry. 48: 184-96. PMID 10924661 DOI: 10.1016/S0006-3223(00)00875-1  1
2000 Harvey PD, Jacobsen H, Mancini D, Parrella M, White L, Haroutunian V, Davis KL. Clinical, cognitive and functional characteristics of long-stay patients with schizophrenia: a comparison of VA and state hospital patients. Schizophrenia Research. 43: 3-9. PMID 10828410 DOI: 10.1016/S0920-9964(99)00182-6  1
2000 Perry E, Martin-Ruiz C, Lee M, Griffiths M, Johnson M, Piggott M, Haroutunian V, Buxbaum JD, Nãsland J, Davis K, Gotti C, Clementi F, Tzartos S, Cohen O, Soreq H, et al. Nicotinic receptor subtypes in human brain ageing, Alzheimer and Lewy body diseases. European Journal of Pharmacology. 393: 215-22. PMID 10771016 DOI: 10.1016/S0014-2999(00)00064-9  1
2000 Näslund J, Haroutunian V, Mohs R, Davis KL, Davies P, Greengard P, Buxbaum JD. Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline. Jama. 283: 1571-7. PMID 10735393 DOI: 10.1001/Jama.283.12.1571  1
2000 Gluck MR, Jayatilleke E, Shaw S, Rowan AJ, Haroutunian V. CNS oxidative stress associated with the kainic acid rodent model of experimental epilepsy. Epilepsy Research. 39: 63-71. PMID 10690755 DOI: 10.1016/S0920-1211(99)00111-4  1
2000 Richardson-Burns SM, Haroutunian V, Davis KL, Watson SJ, Meador-Woodruff JH. Metabotropic glutamate receptor mRNA expression in the schizophrenic thalamus. Biological Psychiatry. 47: 22-8. PMID 10650445 DOI: 10.1016/S0006-3223(99)00207-3  1
2000 Gouras GK, Tsai J, Naslund J, Vincent B, Edgar M, Checler F, Greenfield JP, Haroutunian V, Buxbaum JD, Xu H, Greengard P, Relkin NR. Intraneuronal Abeta42 accumulation in human brain. The American Journal of Pathology. 156: 15-20. PMID 10623648 DOI: 10.1016/S0002-9440(10)64700-1  1
2000 Spielman LA, Ho L, Yemul S, Haroutunian V, Mirjany M, Mukherjee P, Pasinetti GM. Molecular characterization of early Alzheimer's disease Neurobiology of Aging. 21: 189. DOI: 10.1016/S0197-4580(00)82191-0  1
1999 Davis KL, Mohs RC, Marin DB, Purohit DP, Perl DP, Lantz M, Austin G, Haroutunian V. Neuropeptide abnormalities in patients with early Alzheimer disease. Archives of General Psychiatry. 56: 981-7. PMID 10565496 DOI: 10.1001/Archpsyc.56.11.981  1
1999 Haroutunian V, Purohit DP, Perl DP, Marin D, Khan K, Lantz M, Davis KL, Mohs RC. Neurofibrillary tangles in nondemented elderly subjects and mild Alzheimer disease. Archives of Neurology. 56: 713-8. PMID 10369312 DOI: 10.1001/Archneur.56.6.713  1
1999 Dracheva S, Xu M, Kelley KA, Haroutunian V, Holstein GR, Haun S, Silverstein JH, Sealfon SC. Paradoxical locomotor behavior of dopamine D1 receptor transgenic mice. Experimental Neurology. 157: 169-79. PMID 10222120 DOI: 10.1006/Exnr.1999.7037  1
1999 Davis KL, Mohs RC, Marin D, Purohit DP, Perl DP, Lantz M, Austin G, Haroutunian V. Cholinergic markers in elderly patients with early signs of Alzheimer disease. Jama. 281: 1401-6. PMID 10217056 DOI: 10.1001/Jama.281.15.1401  1
1999 Kaplan B, Haroutunian V, Koudinov A, Patael Y, Pras M, Gallo G. Biochemical assay for amyloid beta deposits to distinguish Alzheimer's disease from other dementias. Clinica Chimica Acta; International Journal of Clinical Chemistry. 280: 147-59. PMID 10090532 DOI: 10.1016/S0009-8981(98)00190-9  0.01
1999 Sheu KF, Brown AM, Haroutunian V, Kristal BS, Thaler H, Lesser M, Kalaria RN, Relkin NR, Mohs RC, Lilius L, Lannfelt L, Blass JP. Modulation by DLST of the genetic risk of Alzheimer's disease in a very elderly population. Annals of Neurology. 45: 48-53. PMID 9894876 DOI: 10.1002/1531-8249(199901)45:1<48::Aid-Art9>3.0.Co;2-V  1
1998 Shimon H, Sobolev Y, Davidson M, Haroutunian V, Belmaker RH, Agam G. Inositol levels are decreased in postmortem brain of schizophrenic patients. Biological Psychiatry. 44: 428-32. PMID 9777173 DOI: 10.1016/S0006-3223(98)00071-7  1
1998 Haroutunian V, Perl DP, Purohit DP, Marin D, Khan K, Lantz M, Davis KL, Mohs RC. Regional distribution of neuritic plaques in the nondemented elderly and subjects with very mild Alzheimer disease. Archives of Neurology. 55: 1185-91. PMID 9740112 DOI: 10.1001/Archneur.55.9.1185  1
1998 Powchik P, Davidson M, Haroutunian V, Gabriel SM, Purohit DP, Perl DP, Harvey PD, Davis KL. Postmortem studies in schizophrenia. Schizophrenia Bulletin. 24: 325-41. PMID 9718627 DOI: 10.1093/Oxfordjournals.Schbul.A033330  1
1998 Healy DJ, Haroutunian V, Powchik P, Davidson M, Davis KL, Watson SJ, Meador-Woodruff JH. AMPA receptor binding and subunit mRNA expression in prefrontal cortex and striatum of elderly schizophrenics. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 19: 278-86. PMID 9718591 DOI: 10.1016/S0893-133X(98)00014-1  1
1998 Reznik-Wolf H, Machado J, Haroutunian V, DeMarco L, Walter GF, Goldman B, Davidson M, Johnston JA, Lannfelt L, Dani SU, Friedman E. Somatic mutation analysis of the APP and Presenilin 1 and 2 genes in Alzheimer's disease brains. Journal of Neurogenetics. 12: 55-65. PMID 9666901 DOI: 10.3109/01677069809108555  1
1998 Purohit DP, Perl DP, Haroutunian V, Powchik P, Davidson M, Davis KL. Alzheimer disease and related neurodegenerative diseases in elderly patients with schizophrenia: a postmortem neuropathologic study of 100 cases. Archives of General Psychiatry. 55: 205-11. PMID 9510214 DOI: 10.1001/Archpsyc.55.3.205  1
1997 Meador-Woodruff JH, Haroutunian V, Powchik P, Davidson M, Davis KL, Watson SJ. Dopamine receptor transcript expression in striatum and prefrontal and occipital cortex. Focal abnormalities in orbitofrontal cortex in schizophrenia. Archives of General Psychiatry. 54: 1089-95. PMID 9400344 DOI: 10.1001/Archpsyc.1997.01830240045007  1
1997 Powchik P, Friedman J, Haroutunian V, Greenberg D, Altsteil L, Purohit D, Perl D, Davidson M. Apolipoprotein E4 in schizophrenia: a study of one hundred sixteen cases with concomitant neuropathological examination. Biological Psychiatry. 42: 296-8. PMID 9270908 DOI: 10.1016/S0006-3223(97)00034-6  1
1997 Gabriel SM, Haroutunian V, Powchik P, Honer WG, Davidson M, Davies P, Davis KL. Increased concentrations of presynaptic proteins in the cingulate cortex of subjects with schizophrenia. Archives of General Psychiatry. 54: 559-66. PMID 9193197 DOI: 10.1001/Archpsyc.1997.01830180077010  1
1997 Haroutunian V, Greig N, Pei XF, Utsuki T, Gluck R, Acevedo LD, Davis KL, Wallace WC. Pharmacological modulation of Alzheimer's beta-amyloid precursor protein levels in the CSF of rats with forebrain cholinergic system lesions. Brain Research. Molecular Brain Research. 46: 161-8. PMID 9191090 DOI: 10.1016/S0169-328X(96)00297-5  1
1997 Li G, Aryan M, Silverman JM, Haroutunian V, Perl DP, Birstein S, Lantz M, Marin DB, Mohs RC, Davis KL. The validity of the family history method for identifying Alzheimer disease. Archives of Neurology. 54: 634-40. PMID 9152121 DOI: 10.1001/Archneur.1997.00550170104021  1
1997 Perl DP, Purohit DP, Haroutunian V. Clinicopathologic Correlations Of The AlzheimerʼS Disease Staging System Introduced By Braak And Braak Journal of Neuropathology and Experimental Neurology. 56: 577. DOI: 10.1097/00005072-199705000-00039  1
1997 Powchik P, Haroutunian V, Greenberg D, Altsteil L, Purohit D, Perl D, Davidson M. APOE4 allele frequency is not increased in demented schizophrenics: A study of 116 patients with concomitant postmortem examination Schizophrenia Research. 24: 93. DOI: 10.1016/S0920-9964(97)82254-2  1
1997 Haroutunian V, Powchik P, Gabriel S, Purohit DP, Perl DP, Davis KL. Absence of neuropathological and neurochemical sequela of cognitive deficits in elderly schizophrenics Schizophrenia Research. 24: 33. DOI: 10.1016/S0920-9964(97)82092-0  1
1996 Santucci AC, Knott PJ, Haroutunian V. Excessive serotonin release, not depletion, leads to memory impairments in rats. European Journal of Pharmacology. 295: 7-17. PMID 8925877 DOI: 10.1016/0014-2999(95)00629-X  1
1996 Haroutunian V, Zhou Y, Elder G, Li C, Lazzarini RA. Age-dependent spatial memory deficits in transgenic mice expressing the human mid-sized neurofilament gene: I. Brain Research. Molecular Brain Research. 42: 62-70. PMID 8915581 DOI: 10.1016/S0169-328X(96)00114-3  1
1996 Meador-Woodruff JH, Damask SP, Wang J, Haroutunian V, Davis KL, Watson SJ. Dopamine receptor mRNA expression in human striatum and neocortex. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 15: 17-29. PMID 8797188 DOI: 10.1016/0893-133X(95)00150-C  1
1996 Li G, Silverman JM, Altstiel LD, Haroutunian V, Perl DP, Purohit D, Birstein S, Lantz M, Mohs RC, Davis KL. Apolipoprotein E-epsilon 4 allele and familial risk in Alzheimer's disease. Genetic Epidemiology. 13: 285-98. PMID 8797010 DOI: 10.1002/(Sici)1098-2272(1996)13:3<285::Aid-Gepi5>3.0.Co;2-5  1
1996 Gabriel SM, Davidson M, Haroutunian V, Powchik P, Bierer LM, Purohit DP, Perl DP, Davis KL. Neuropeptide deficits in schizophrenia vs. Alzheimer's disease cerebral cortex. Biological Psychiatry. 39: 82-91. PMID 8717605 DOI: 10.1016/0006-3223(95)00066-6  1
1996 Klein JT, Davis L, Olsen GE, Wong GS, Huger FP, Smith CP, Petko WW, Cornfeldt M, Wilker JC, Blitzer RD, Landau E, Haroutunian V, Martin LL, Effland RC. Synthesis and structure-activity relationships of N-propyl-N-(4-pyridinyl)-1H-indol-1-amine (besipirdine) and related analogs as potential therapeutic agents for Alzheimer's disease. Journal of Medicinal Chemistry. 39: 570-81. PMID 8558529 DOI: 10.1021/Jm9506433  1
1995 Miller M, Haroutunian V, Wiltshire-Clement M. Altered alertness of vasopressin-secreting transgenic mice. Peptides. 16: 1329-33. PMID 8745040 DOI: 10.1016/0196-9781(95)02047-0  0.01
1995 Bierer LM, Haroutunian V, Gabriel S, Knott PJ, Carlin LS, Purohit DP, Perl DP, Schmeidler J, Kanof P, Davis KL. Neurochemical correlates of dementia severity in Alzheimer's disease: relative importance of the cholinergic deficits. Journal of Neurochemistry. 64: 749-60. PMID 7830069 DOI: 10.1046/J.1471-4159.1995.64020749.X  1
1995 Wallace WC, Lieberburg I, Schenk D, Vigo-Pelfrey C, Davis KL, Haroutunian V. Chronic elevation of secreted amyloid precursor protein in subcortically lesioned rats, and its exacerbation in aged rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 4896-905. PMID 7623120 DOI: 10.1523/Jneurosci.15-07-04896.1995  1
1995 Santucci AC, Kanof PD, Haroutunian V. Transient enhancement of cholinergic neurochemical markers induced by NGF in aged F344 rats. Dementia (Basel, Switzerland). 6: 179-84. PMID 7550595 DOI: 10.1159/000106943  1
1995 Lawlor BA, Ryan TM, Bierer LM, Schmeidler J, Haroutunian V, Mohs R, Davis KL. Lack of association between clinical symptoms and postmortem indices of brain serotonin function in Alzheimer's disease. Biological Psychiatry. 37: 895-6. PMID 7548465 DOI: 10.1016/0006-3223(95)00035-F  1
1995 Gabriel SM, Knott PJ, Haroutunian V. Alterations in cerebral cortical galanin concentrations following neurotransmitter-specific subcortical lesions in the rat. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 5526-34. PMID 7543947 DOI: 10.1523/Jneurosci.15-08-05526.1995  1
1995 Santucci AC, Knott PJ, Haroutunian V. 5,7-DHT-induced lesions of the nucleus basalis or frontal cortex do not block passive avoidance retention impairments produced by p-chloroamphetamine in rats Psychobiology. 23: 139-143. DOI: 10.3758/Bf03327069  1
1995 Perl DP, Davidson M, Haroutunian V, Davis KL. ALZHEIMERʼS DISEASE AND RELATED NEURODEGENERATIVE DISEASES IN ELDERLY SCHIZOPHRENIC PATIENTS: A POST-MORTEM NEUROPATHOLOGIC STUDY OF 100 CASES. DP Purohit Journal of Neuropathology and Experimental Neurology. 54: 460. DOI: 10.1097/00005072-199505000-00211  1
1995 Golier J, Davidson M, Haroutunian VH, Powchik P, Purohit D, Perl D, Davis KL. Neuropathologic study of 101 elderly institutionalized schizophrenics Schizophrenia Research. 15: 28. DOI: 10.1016/0920-9964(95)95098-T  1
1995 Powchik P, Davidson M, Gabriel SM, Haroutunian V, Harvey PD, Davis KL. Somatostatin and NPY deficits in schizophrenic cortex Schizophrenia Research. 15: 26-27. DOI: 10.1016/0920-9964(95)95093-O  1
1995 Davidson M, Powchik P, Gabriel SM, Haroutunian V, Harvey PD, Davis KL. Correlations between temporal lobe synaptic protein immunoactivity and schizophrenic psychosis Schizophrenia Research. 15: 26. DOI: 10.1016/0920-9964(95)95091-M  1
1994 Haroutunian V, Davidson M, Kanof PD, Perl DP, Powchik P, Losonczy M, McCrystal J, Purohit DP, Bierer LM, Davis KL. Cortical cholinergic markers in schizophrenia. Schizophrenia Research. 12: 137-44. PMID 8043524 DOI: 10.1016/0920-9964(94)90071-X  1
1994 Perry EK, Haroutunian V, Davis KL, Levy R, Lantos P, Eagger S, Honavar M, Dean A, Griffiths M, McKeith IG. Neocortical cholinergic activities differentiate Lewy body dementia from classical Alzheimer's disease. Neuroreport. 5: 747-9. PMID 8018843 DOI: 10.1097/00001756-199403000-00002  1
1994 Wallace W, Brane D, Hsu N, Khowong N, Merril CR, Haroutunian V. Characterization of gene expression in the cerebral cortices of rat brains containing subcortical lesions. Applied and Theoretical Electrophoresis : the Official Journal of the International Electrophoresis Society. 4: 33-8. PMID 7811765  1
1994 Altstiel LD, Greenberg D, Haroutunian V, Perl DP, Keddache M, Purohit DP, Yang X, Mohs R, Davis KL. Apolipoprotein E allele ϵ4 in autopsy-confirmed Alzheimer's disease and cerebrovascular disease Neurobiology of Aging. 15. DOI: 10.1016/0197-4580(94)93090-2  1
1994 Powchik P, Davidson M, Gabriel S, Haroutunian V, Perl D, Purohit D, Davis KL. Neuropeptides discriminate brains of schizophrenics from normals Biological Psychiatry. 35: 733. DOI: 10.1016/0006-3223(94)91083-9  1
1994 Golier J, Mavidson D, haroutunian VH, Powchik P, Purohit D, Perl D, Davis KL. A neurohistological study of elderly institutionalized schizophrenic and affective disorder patients Biological Psychiatry. 35: 703. DOI: 10.1016/0006-3223(94)90975-X  1
1994 Wallace W, Lieberburg I, Davis KL, Fiber E, Gluck R, Haroutunian V. Induction of APP results in its secretion and production of B-amyloid in subcortically lesioned rats Biological Psychiatry. 35: 671. DOI: 10.1016/0006-3223(94)90860-5  1
1993 Santucci AC, Kanof PD, Haroutunian V. Cholinergic marker deficits induced by lesions of the nucleus basalis of Meynert are attenuated by nerve growth factor in young, but not in aged, F344 rats. Brain Research. 609: 327-32. PMID 8508314  1
1993 Purohit DP, Davidson M, Perl DP, Powchik P, Haroutunian VH, Bierer LM, McCrystal J, Losonczy M, Davis KL. Severe cognitive impairment in elderly schizophrenic patients: a clinicopathological study. Biological Psychiatry. 33: 255-60. PMID 8471678 DOI: 10.1016/0006-3223(93)90291-K  1
1993 Schmauss C, Haroutunian V, Davis KL, Davidson M. Selective loss of dopamine D3-type receptor mRNA expression in parietal and motor cortices of patients with chronic schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 90: 8942-6. PMID 8415635 DOI: 10.1073/Pnas.90.19.8942  1
1993 Wallace W, Ahlers ST, Gotlib J, Bragin V, Sugar J, Gluck R, Shea PA, Davis KL, Haroutunian V. Amyloid precursor protein in the cerebral cortex is rapidly and persistently induced by loss of subcortical innervation. Proceedings of the National Academy of Sciences of the United States of America. 90: 8712-6. PMID 8378353 DOI: 10.1073/Pnas.90.18.8712  1
1993 Santucci AC, Gluck R, Kanof PD, Haroutunian V. Induction of memory and cortical cholinergic neurochemical recovery with combine fetal transplantation and GM1 treatments in rats with lesions of the NBM. Dementia (Basel, Switzerland). 4: 273-81. PMID 8261024 DOI: 10.1159/000107333  1
1993 Powchik P, Davidson M, Nemeroff CB, Haroutunian V, Purohit D, Losonczy M, Bissette G, Perl D, Ghanbari H, Miller B. Alzheimer's-disease-related protein in geriatric schizophrenic patients with cognitive impairment. The American Journal of Psychiatry. 150: 1726-7. PMID 8214183 DOI: 10.1176/Ajp.150.11.1726  1
1993 Bierer LM, Knott PJ, Schmeidler JM, Marin DB, Ryan TM, Haroutunian V, Purohit DP, Perl DP, Mohs RC, Davis KL. Post-mortem examination of dopaminergic parameters in Alzheimer's disease: relationship to noncognitive symptoms. Psychiatry Research. 49: 211-7. PMID 8177917 DOI: 10.1016/0165-1781(93)90062-L  1
1993 Wallace W, Haroutunian V. Using the subcortically lesioned rat cortex to understand the physiological role of amyloid precursor protein. Behavioural Brain Research. 57: 199-206. PMID 8117425 DOI: 10.1016/0166-4328(93)90136-E  1
1992 Johnson G, Gotlib J, Haroutunian V, Bierer L, Nairn AC, Merril C, Wallace W. Increased phosphorylation of elongation factor 2 in Alzheimer's disease. Brain Research. Molecular Brain Research. 15: 319-26. PMID 1331687 DOI: 10.1016/0169-328X(92)90124-T  1
1992 Bierer LM, Silverman JM, Mohs RC, Haroutunian V, Lis G, Purohit D, Breitner JCS, Perl DP, Davis KL. Morbid risk to first degree relatives of neuropathologically confirmed cases of alzheimer's disease Dementia and Geriatric Cognitive Disorders. 3: 134-139. DOI: 10.1159/000107008  1
1991 Santucci AC, Haroutunian V, Davis KL. Pharmacological alleviation of combined cholinergic/noradrenergic lesion-induced memory deficits in rats. Clinical Neuropharmacology. 14: S1-8. PMID 1913705 DOI: 10.1097/00002826-199114001-00002  1
1991 Santucci AC, Kanof PD, Haroutunian V. Fetal transplant-induced restoration of spatial memory in rats with lesions of the nucleus basalis of Meynert. Journal of Neural Transplantation & Plasticity. 2: 65-74. PMID 1868119 DOI: 10.1155/Np.1991.65  1
1991 Parks KM, Sugar JE, Haroutunian V, Bierer L, Perl D, Wallace WC. Reduced in vitro phosphorylation of synapsin I (site 1) in Alzheimer's disease postmortem tissues. Brain Research. Molecular Brain Research. 9: 125-34. PMID 1850067 DOI: 10.1016/0169-328X(91)90137-M  1
1991 Perez N, Sugar J, Charya S, Johnson G, Merril C, Bierer L, Perl D, Haroutunian V, Wallace W. Increased synthesis and accumulation of heat shock 70 proteins in Alzheimer's disease. Brain Research. Molecular Brain Research. 11: 249-54. PMID 1661822 DOI: 10.1016/0169-328X(91)90033-T  1
1991 Wallace WC, Bragin V, Robakis NK, Sambamurti K, VanderPutten D, Merril CR, Davis KL, Santucci AC, Haroutunian V. Increased biosynthesis of Alzheimer amyloid precursor protein in the cerebral cortex of rats with lesions of the nucleus basalis of Meynert. Brain Research. Molecular Brain Research. 10: 173-8. PMID 1649369 DOI: 10.1016/0169-328X(91)90108-A  1
1990 Haroutunian V, Mantin R, Kanof PD. Frontal cortex as the site of action of physostigmine in nbM-lesioned rats. Physiology & Behavior. 47: 203-6. PMID 2326337 DOI: 10.1016/0031-9384(90)90061-8  1
1990 Haroutunian V, Kanof PD, Tsuboyama G, Davis KL. Restoration of cholinomimetic activity by clonidine in cholinergic plus noradrenergic lesioned rats. Brain Research. 507: 261-6. PMID 2110845 DOI: 10.1016/0006-8993(90)90280-O  1
1990 Haroutunian V, Santucci AC, Davis KL. Implications of multiple transmitter system lesions for cholinomimetic therapy in Alzheimer's disease. Progress in Brain Research. 84: 333-46. PMID 1980019 DOI: 10.1016/S0079-6123(08)60917-6  1
1990 Bierer LM, Perl DP, Haroutunian V, Mohs RC, Davis KL. Neurofibrillary tangles, Alzheimer's disease and Lewy bodies. Lancet. 335: 163. PMID 1967448 DOI: 10.1016/0140-6736(90)90031-Y  1
1990 Santucci AC, Kanof PD, Haroutunian V. Serotonergic Modulation of Cholinergic Systems Involved in Learning and Memory in Rats Dementia and Geriatric Cognitive Disorders. 1: 151-155. DOI: 10.1159/000107135  1
1989 Benson DM, Blitzer RD, Haroutunian V, Landau EM. Functional muscarinic supersensitivity in denervated rat hippocampus. Brain Research. 478: 399-402. PMID 2924138 DOI: 10.1016/0006-8993(89)91524-2  1
1989 Haroutunian V, Kanof PD, Davis KL. Interactions of forebrain cholinergic and somatostatinergic systems in the rat. Brain Research. 496: 98-104. PMID 2804656 DOI: 10.1016/0006-8993(89)91055-X  1
1989 Santucci AC, Haroutunian V. Nucleus basalis lesions impair memory in rats trained on nonspatial and spatial discrimination tasks. Physiology & Behavior. 45: 1025-31. PMID 2780863 DOI: 10.1016/0031-9384(89)90233-3  1
1989 Shutske GM, Pierrat FA, Kapples KJ, Cornfeldt ML, Szewczak MR, Huger FP, Bores GM, Haroutunian V, Davis KL. 9-Amino-1,2,3,4-tetrahydroacridin-1-ols: synthesis and evaluation as potential Alzheimer's disease therapeutics. Journal of Medicinal Chemistry. 32: 1805-13. PMID 2754707 DOI: 10.1021/Jm00128A024  1
1989 Haroutunian V, Kanof PD, Davis KL. Attenuation of nucleus basalis of Meynert lesion-induced cholinergic deficits by nerve growth factor. Brain Research. 487: 200-3. PMID 2752286 DOI: 10.1016/0006-8993(89)90960-8  1
1989 Santucci AC, Haroutunian V, Tsuboyama GK, Kanof PD, Davis KL. Therapeutics of Alzheimer's disease for clinical and pre-clinical issues. Progress in Clinical and Biological Research. 317: 1111-20. PMID 2690088  1
1989 Santucci AC, Kanof PD, Haroutunian V. Infusion of NMDA into the nucleus basalis of Meynert, frontal cortex or lateral ventricle in rats: effect on memory and cholinergic brain neurochemistry. Pharmacology, Biochemistry, and Behavior. 33: 485-8. PMID 2682674 DOI: 10.1016/0091-3057(89)90535-2  1
1989 Anderson J, Wallace W, Snyder S, Haroutunian V, Roberts JL, Lieberburg I. Cellular forms of the rat and human beta-amyloid precursor protein (BAPP). Brain Research. 478: 391-8. PMID 2647209 DOI: 10.1016/0006-8993(89)91523-0  1
1989 Anderson JP, Refolo LM, Wallace W, Mehta P, Krishnamurthi M, Gotlib J, Bierer L, Haroutunian V, Perl D, Robakis NK. Differential brain expression of the Alzheimer's amyloid precursor protein. The Embo Journal. 8: 3627-32. PMID 2583112 DOI: 10.1002/J.1460-2075.1989.Tb08536.X  1
1989 Santucci AC, Kanof PD, Haroutunian V. Effect of physostigmine on memory consolidation and retrieval processes in intact and nucleus basalis-lesioned rats. Psychopharmacology. 99: 70-4. PMID 2506606 DOI: 10.1007/Bf00634455  1
1989 Good PF, Perl DP, Haroutunian V, Bierer L. Aluminum Accumulation In The Neurofibrillary Tangles Of AlzheimerʼS Disease: Not Related To Fixative Contamination Journal of Neuropathology and Experimental Neurology. 48: 334. DOI: 10.1097/00005072-198905000-00105  1
1989 Haroutunian V, Santucci AC, Gluck R, Davis KL. Effects of chronic GM1 administration on transplant-induced reversal of memory impairments in nbm lesioned rats Biological Psychiatry. 25. DOI: 10.1016/0006-3223(89)91726-5  1
1989 Bierer LM, Perl DP, Haroutunian V, Ko G, Davis KL. Alzheimer's disease cases with subcortical lewy bodies show diminished neocortical tangle formation Biological Psychiatry. 25. DOI: 10.1016/0006-3223(89)91723-X  1
1989 Charya S, Parks KM, Merril C, Bierer L, Perl D, Haroutunian V, Davis KL, Wallace W. Examination of proteins whose synthesis is Altered in Alzheimer's disease Biological Psychiatry. 25. DOI: 10.1016/0006-3223(89)91722-8  1
1989 Anderson JP, Refolo LM, Haroutunian V, Bierer L, Perl D, Robakis NK, Davis KL. Processing and regional specificity of variant forms of the Alzheimer amyloid precursor protein Biological Psychiatry. 25. DOI: 10.1016/0006-3223(89)91721-6  1
1989 Ko GN, Raskind M, Dorsa D, Haroutunian V, Horvath TB, Bierer L, Lim S, Nora R, Smood J, Scalla E, Davis KL. ALPHA2 Adrenergic receptors in Alzheimer's disease and schizophrenic cortex frontal Biological Psychiatry. 25. DOI: 10.1016/0006-3223(89)91718-6  1
1989 Knott P, Haroutunian V, Bierer L, Perl D, Handler M, DeLeon M, Yang R, Davis K. Correlations post-mortem between ventricular CSF and cortical tissue concentrations of MHPG, 5-HIAA and HVA in Alzheimer's disease Biological Psychiatry. 25. DOI: 10.1016/0006-3223(89)91712-5  1
1988 Shutske GM, Pierrat FA, Cornfeldt ML, Szewczak MR, Huger FP, Bores GM, Haroutunian V, Davis KL. (+/-)-9-Amino-1,2,3,4-tetrahydroacridin-1-ol. A potential Alzheimer's disease therapeutic of low toxicity. Journal of Medicinal Chemistry. 31: 1278-9. PMID 3385720 DOI: 10.1021/Jm00402A002  1
1988 Haroutunian V, Knott P, Davis KL. Effects of mesocortical dopaminergic lesions upon subcortical dopaminergic function. Psychopharmacology Bulletin. 24: 341-4. PMID 3153491  1
1988 Davis KL, Haroutunian V, Kanof P. Therapeutics Of Alzheimer??S Disease For Clinical & Pre Clinical Issues Alzheimer Disease & Associated Disorders. 2: 205. DOI: 10.1097/00002093-198802030-00054  1
1987 Haroutunian V, Mantin R, Campbell GA, Tsuboyama GK, Davis KL. Cysteamine-induced depletion of central somatostatin-like immunoactivity: effects on behavior, learning, memory and brain neurochemistry. Brain Research. 403: 234-42. PMID 3828820 DOI: 10.1016/0006-8993(87)90060-6  1
1986 Haroutunian V, Kanof PD, Davis KL. Partial reversal of lesion-induced deficits in cortical cholinergic markers by nerve growth factor. Brain Research. 386: 397-9. PMID 3779417 DOI: 10.1016/0006-8993(86)90179-4  1
1986 Haroutunian V, Kanof PD, Tsuboyama GK, Campbell GA, Davis KL. Animal models of Alzheimer's disease: behavior, pharmacology, transplants. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 13: 385-93. PMID 2878711 DOI: 10.1017/S0317167100036957  1
1985 Haroutunian V, Kanof P, Davis KL. Pharmacological alleviation of cholinergic lesion induced memory deficits in rats. Life Sciences. 37: 945-52. PMID 4040999 DOI: 10.1016/0024-3205(85)90531-4  1
1985 Haroutunian V, Barnes E, Davis KL. Cholinergic modulation of memory in rats. Psychopharmacology. 87: 266-71. PMID 3001803 DOI: 10.1007/Bf00432705  1
1985 Haroutunian V, Davis KL. Commentary on review by gash et al. A clinical perspective on neural transplantation and potential applications to the aged brain Neurobiology of Aging. 6: 166-167. DOI: 10.1016/0197-4580(85)90041-7  1
1985 Johns CA, Haroutunian V, Greenwald BS, Mohs RC, Davis BM, Kanof P, Horvath TB, Davis MDKL. Development of cholinergic drugs for the treatment of Alzheimer's disease Drug Development Research. 5: 77-96. DOI: 10.1002/Ddr.430050108  1
1983 Campbell BA, Haroutunian V. Perceptual sharpening in the developing rat. Journal of Comparative Psychology (Washington, D.C. : 1983). 97: 3-11. PMID 6872504 DOI: 10.1037//0735-7036.97.1.3  1
1982 Haroutunian V, Campbell BA. Neural control of the heart-rate-orienting response in preweanling rats. Behavioral and Neural Biology. 36: 24-39. PMID 7168728 DOI: 10.1016/S0163-1047(82)90212-6  1
1981 Campbell BA, Haroutunian V. Effects of age on long-term memory: retention of fixed interval responding. Journal of Gerontology. 36: 338-41. PMID 7229281 DOI: 10.1093/Geronj/36.3.338  1
1981 Haroutunian V, Campbell BA. Development and habituation of the heart rate orienting response to auditory and visual stimuli in the rat. Journal of Comparative and Physiological Psychology. 95: 166-74. PMID 7217409 DOI: 10.1037/H0077756  1
1981 Thomas DA, Haroutunian V, Barfield RJ. Behavioral and physiological habituation to an ultrasonic stimulus Bulletin of the Psychonomic Society. 17: 279-282. DOI: 10.3758/Bf03333740  1
1980 Stehouwer DJ, Haroutunian V, Campbell BA. Generalization of habituation to electrical stimulation of the forelimb in neonatal and preweanling rats. Behavioral and Neural Biology. 29: 203-15. PMID 7387590 DOI: 10.1016/S0163-1047(80)90534-8  1
1979 Haroutunian V, Riccio DC. Age-dependent effects of preconditioning aversive experiences on the retention of conditioned fear in weanling rats. Behavioral and Neural Biology. 26: 248-53. PMID 496783 DOI: 10.1016/S0163-1047(79)92659-1  1
1979 Haroutunian V, Riccio DC. Reduction of ontogenetic retention decrements in rats by pretraining stressful experiences. Journal of Comparative and Physiological Psychology. 93: 501-11. PMID 479395 DOI: 10.1037/H0077567  1
1979 Haroutunian V, Campbell BA. Emergence of interoceptive and exteroceptive control of behavior in rats. Science (New York, N.Y.). 205: 927-9. PMID 472715 DOI: 10.1126/Science.472715  1
1979 Haroutunian V, Riccio DC. Drug-induced "arousal" and the effectiveness of CS exposure in the reinstatement of memory. Behavioral and Neural Biology. 26: 115-20. PMID 224855 DOI: 10.1016/S0163-1047(79)92959-5  1
1977 Haroutunian V, Riccio DC. Effect of arousal conditions during reinstatement treatment upon learned fear in young rats. Developmental Psychobiology. 10: 25-32. PMID 844652 DOI: 10.1002/Dev.420100105  1
1977 Riccio DC, Haroutunian V. Failure to learn in a taste aversion paradigm: Associative or performance deficit? Bulletin of the Psychonomic Society. 10: 219-222. DOI: 10.3758/Bf03329329  1
1976 Haroutunian V, Riccio DC, Gans DP. Suppression of drinking following rotational stimulation as an index of motion sickness in the rat Physiological Psychology. 4: 467-472. DOI: 10.3758/Bf03326598  1
1975 Haroutunian V, Riccio DC. Acquisition of rotation-induced taste aversion as a function of drinking-treatment delay Physiological Psychology. 3: 273-277. DOI: 10.3758/Bf03337524  1
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