| Year |
Citation |
Score |
| 2023 |
Nandikolla A, Khetmalis YM, Venkata Siva Kumar B, Chandu A, Karan Kumar B, Shetye G, Ma R, Murugesan S, Franzblau SG, Chandra Sekhar KVG. Design, synthesis and biological evaluation of phenanthridine amide and 1,2,3-triazole analogues against . Rsc Medicinal Chemistry. 14: 1549-1561. PMID 37593576 DOI: 10.1039/d3md00115f |
0.31 |
|
| 2023 |
Khatri Chhetri B, Bhanushali R, Liang Y, Cepeda MR, Niradininoco AK, Soapi K, Wan B, Qader M, Franzblau SG, Kubanek J. Isolation and Characterization of Anti-Mycobacterial Natural Products from a sp. Marine Sponge. Journal of Natural Products. PMID 36881908 DOI: 10.1021/acs.jnatprod.2c01003 |
0.321 |
|
| 2023 |
Zhang J, Lair C, Roubert C, Amaning K, Barrio MB, Benedetti Y, Cui Z, Xing Z, Li X, Franzblau SG, Baurin N, Bordon-Pallier F, Cantalloube C, Sans S, Silve S, et al. Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents. Cell. PMID 36827973 DOI: 10.1016/j.cell.2023.01.043 |
0.38 |
|
| 2022 |
Lee SY, Shetye GS, Son SR, Lee H, Klein LL, Yoshihara JK, Ma R, Franzblau SG, Cho S, Jang DS. Anti-Microbial Activity of Aliphatic Alcohols from Chinese Black Cardamom (-) against H37Rv. Plants (Basel, Switzerland). 12. PMID 36616162 DOI: 10.3390/plants12010034 |
0.343 |
|
| 2022 |
Luo W, Huang Z, Xu D, Yang M, Zhu Y, Shen L, Chen S, Tao X, Bin W, Hu Y, Franzblau SG, Jiang N, Wei Y, Wei X, Ding CZ. Discovery and preclinical evaluations of JBD0131, a novel nitrodihydro-imidazooxazole anti-tuberculosis agent. Bioorganic & Medicinal Chemistry Letters. 72: 128871. PMID 35777718 DOI: 10.1016/j.bmcl.2022.128871 |
0.358 |
|
| 2022 |
Rajeswaran W, Ashkar SR, Lee PH, Yeomans L, Shin Y, Franzblau SG, Murakami KS, Showalter HD, Garcia GA. Optimization of Benzoxazinorifamycins to Improve RNA Polymerase Inhibition and Treatment of Tuberculosis. Acs Infectious Diseases. PMID 35772744 DOI: 10.1021/acsinfecdis.1c00636 |
0.307 |
|
| 2022 |
Ashkar SR, Rajeswaran W, Lee PH, Yeomans L, Thrasher CM, Franzblau SG, Murakami KS, Showalter HD, Garcia GA. Optimization of Benzoxazinorifamycins to Minimize hPXR Activation for the Treatment of Tuberculosis and HIV Coinfection. Acs Infectious Diseases. PMID 35772743 DOI: 10.1021/acsinfecdis.1c00635 |
0.354 |
|
| 2022 |
Huang Z, Luo W, Xu D, Guo F, Yang M, Zhu Y, Shen L, Chen S, Tang D, Li L, Li Y, Wang B, Franzblau SG, Ding CZ. Discovery and preclinical profile of sudapyridine (WX-081), a novel anti-tuberculosis agent. Bioorganic & Medicinal Chemistry Letters. 71: 128824. PMID 35636648 DOI: 10.1016/j.bmcl.2022.128824 |
0.348 |
|
| 2021 |
Sutherland HS, Lu GL, Tong AST, Conole D, Franzblau SG, Upton AM, Lotlikar MU, Cooper CB, Palmer BD, Choi PJ, Denny WA. Synthesis and structure-activity relationships for a new class of tetrahydronaphthalene amide inhibitors of Mycobacterium tuberculosis. European Journal of Medicinal Chemistry. 229: 114059. PMID 34963068 DOI: 10.1016/j.ejmech.2021.114059 |
0.391 |
|
| 2021 |
Primi MC, Tavares MT, Klein LL, Izard T, Sant'Anna CMR, Franzblau SG, Ferreira EI. Design of Novel Phosphopantetheine Adenylyltransferase Inhibitors: a Potential New Approach to Tackle Mycobacterium tuberculosis. Current Topics in Medicinal Chemistry. PMID 34323186 DOI: 10.2174/1568026621666210728094804 |
0.305 |
|
| 2021 |
Shetye GS, Choi KB, Kim CY, Franzblau SG, Cho S. Profiling of Anti-tubercular Compounds by Rapid, Efficient, and Non-Destructive Assays Using Auto-luminescent . Antimicrobial Agents and Chemotherapy. AAC0028221. PMID 34097493 DOI: 10.1128/AAC.00282-21 |
0.323 |
|
| 2021 |
Liu R, Markley L, Miller PA, Franzblau S, Shetye G, Ma R, Savková K, Mikušová K, Lee BS, Pethe K, Moraski GC, Miller MJ. Hydride-induced Meisenheimer complex formation reflects activity of nitro aromatic anti-tuberculosis compounds. Rsc Medicinal Chemistry. 12: 62-72. PMID 34046598 DOI: 10.1039/d0md00390e |
0.365 |
|
| 2021 |
Nandikolla A, Srinivasarao S, Khetmalis YM, Kumar BK, Murugesan S, Shetye G, Ma R, Franzblau SG, Sekhar KVGC. Design, synthesis and biological evaluation of novel 1,2,3-triazole analogues of Imidazo-[1,2-a]-pyridine-3-carboxamide against Mycobacterium tuberculosis. Toxicology in Vitro : An International Journal Published in Association With Bibra. 105137. PMID 33684466 DOI: 10.1016/j.tiv.2021.105137 |
0.343 |
|
| 2020 |
Lu GL, Tong AST, Conole D, Sutherland HS, Choi PJ, Franzblau SG, Upton AM, Lotlikar MU, Cooper CB, Denny WA, Palmer BD. Synthesis and structure-activity relationships for tetrahydroisoquinoline-based inhibitors of Mycobacterium tuberculosis. Bioorganic & Medicinal Chemistry. 28: 115784. PMID 33007562 DOI: 10.1016/j.bmc.2020.115784 |
0.313 |
|
| 2020 |
Velappan AB, Kesamsetty D, Datta D, Ma R, Hari N, Franzblau SG, Debnath J. 1,3-Oxazine-2-one derived dual-targeted molecules against replicating and non-replicating forms of Mycobacterium tuberculosis. European Journal of Medicinal Chemistry. 208: 112835. PMID 32977201 DOI: 10.1016/J.Ejmech.2020.112835 |
0.44 |
|
| 2020 |
Velappan AB, Datta D, Ma R, Rana S, Ghosh KS, Hari N, Franzblau SG, Debnath J. 2-Aryl benzazole derived new class of anti-tubercular compounds: Endowed to eradicate mycobacterium tuberculosis in replicating and non-replicating forms. Bioorganic Chemistry. 103: 104170. PMID 32890990 DOI: 10.1016/J.Bioorg.2020.104170 |
0.466 |
|
| 2020 |
de Souza PC, Fernandes GFS, Marino LB, Ribeiro CM, Silva PBD, Chorilli M, Silva CSP, Resende FA, Solcia MC, de Grandis RA, Costa CAS, Cho SH, Wang Y, Franzblau SG, Dos Santos JL, et al. Furoxan derivatives demonstrated in vivo efficacy by reducing Mycobacterium tuberculosis to undetectable levels in a mouse model of infection. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 130: 110592. PMID 32763822 DOI: 10.1016/J.Biopha.2020.110592 |
0.419 |
|
| 2020 |
Nizi MG, Desantis J, Nakatani Y, Massari S, Mazzarella MA, Shetye G, Sabatini S, Barreca ML, Manfroni G, Felicetti T, Rushton-Green R, Hards K, Latacz G, Satała G, Bojarski AJ, ... ... Franzblau SG, et al. Antitubercular polyhalogenated phenothiazines and phenoselenazine with reduced binding to CNS receptors. European Journal of Medicinal Chemistry. 201: 112420. PMID 32526553 DOI: 10.1016/J.Ejmech.2020.112420 |
0.453 |
|
| 2020 |
Shetye GS, Franzblau SG, Cho S. New tuberculosis drug targets, their inhibitors, and potential therapeutic impact. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 32275897 DOI: 10.1016/J.Trsl.2020.03.007 |
0.425 |
|
| 2020 |
Macabeo APG, Flores AIG, Fernandez RAT, Budde S, Faderl C, Dahse HM, Franzblau SG. Antitubercular and cytotoxic polyoxygenated cyclohexane derivatives from . Natural Product Research. 1-4. PMID 32202440 DOI: 10.1080/14786419.2020.1741579 |
0.381 |
|
| 2020 |
Zhou B, Shetye G, Yu Y, Santarsiero BD, Klein LL, Abad-Zapatero C, Wolf NM, Cheng J, Jin Y, Lee H, Suh JW, Lee H, Bisson J, McAlpine JB, Chen SN, ... ... Franzblau SG, et al. Antimycobacterial Rufomycin Analogues from Strain MJM3502. Journal of Natural Products. PMID 32031795 DOI: 10.1021/Acs.Jnatprod.9B01095 |
0.45 |
|
| 2019 |
Sutherland HS, Tong AST, Choi PJ, Blaser A, Franzblau SG, Cooper CB, Upton AM, Lotlikar M, Denny WA, Palmer BD. Variations in the C-unit of bedaquiline provides analogues with improved biology and pharmacology. Bioorganic & Medicinal Chemistry. 115213. PMID 31810890 DOI: 10.1016/J.Bmc.2019.115213 |
0.413 |
|
| 2019 |
Wang A, Lv K, Tao Z, Gu J, Fu L, Liu M, Wan B, Franzblau SG, Ma C, Ma X, Han B, Wang A, Xu S, Lu Y. Identification of benzothiazinones containing an oxime functional moiety as new anti-tuberculosis agents. European Journal of Medicinal Chemistry. 181: 111595. PMID 31408806 DOI: 10.1016/J.Ejmech.2019.111595 |
0.494 |
|
| 2019 |
Grzelak EM, Choules MP, Gao W, Cai G, Wan B, Wang Y, McAlpine JB, Cheng J, Jin Y, Lee H, Suh JW, Pauli GF, Franzblau SG, Jaki BU, Cho S. Strategies in anti-Mycobacterium tuberculosis drug discovery based on phenotypic screening. The Journal of Antibiotics. PMID 31292530 DOI: 10.1038/S41429-019-0205-9 |
0.416 |
|
| 2019 |
Yang X, Yuan T, Ma R, Chacko K, Smith M, Deikus G, Sebra R, Kasarkskis A, van Bakel H, Franzblau SG, Sampson NS. The Mce3R stress-resistance pathway is vulnerable to small molecule targeting that improves tuberculosis drug activities. Acs Infectious Diseases. PMID 31012313 DOI: 10.1021/Acsinfecdis.9B00099 |
0.431 |
|
| 2019 |
Hu X, Wan B, Liu Y, Shen J, Franzblau SG, Zhang T, Ding K, Lu X. Identification of Pyrazolo[1,5-]pyridine-3-carboxamide Diaryl Derivatives as Drug Resistant Antituberculosis Agents. Acs Medicinal Chemistry Letters. 10: 295-299. PMID 30891129 DOI: 10.1021/Acsmedchemlett.8B00410 |
0.381 |
|
| 2019 |
Sutherland HS, Tong AST, Choi PJ, Blaser A, Conole D, Franzblau SG, Lotlikar MU, Cooper CB, Upton AM, Denny WA, Palmer BD. 3,5-Dialkoxypyridine analogues of bedaquiline are potent antituberculosis agents with minimal inhibition of the hERG channel. Bioorganic & Medicinal Chemistry. PMID 30803745 DOI: 10.1016/J.Bmc.2019.02.026 |
0.473 |
|
| 2019 |
Blaser A, Sutherland HS, Tong AST, Choi PJ, Conole D, Franzblau SG, Cooper CB, Upton AM, Lotlikar M, Denny WA, Palmer BD. Structure-activity relationships for unit C pyridyl analogues of the tuberculosis drug bedaquiline. Bioorganic & Medicinal Chemistry. PMID 30792104 DOI: 10.1016/J.Bmc.2019.02.025 |
0.44 |
|
| 2019 |
Garcellano RC, Cort JR, Moinuddin SGA, Franzblau SG, Ma R, Aguinaldo AM. An iboga alkaloid chemotaxonomic marker from endemic Tabernaemontana ternifolia with antitubercular activity. Natural Product Research. 1-5. PMID 30773907 DOI: 10.1080/14786419.2018.1550759 |
0.361 |
|
| 2019 |
Choules MP, Wolf NM, Lee H, Anderson JR, Grzelak EM, Wang Y, Ma R, Gao W, McAlpine JB, Jin YY, Cheng J, Lee H, Suh JW, Duc NM, Paik S, ... ... Franzblau SG, et al. Rufomycin Targets ClpC1 Proteolysis in and . Antimicrobial Agents and Chemotherapy. PMID 30602512 DOI: 10.1128/Aac.02204-18 |
0.303 |
|
| 2019 |
Wolf NM, Lee H, Nam J, Hong J, Duc NM, Ho NA, Lee H, Suh J, Pauli GF, Franzblau SG, Cho S, Abad-Zapatero C. Structures of ClpC1-NTD with potent anti-TB cyclic peptides Rufomycin and Ecumicin: implications for the mechanism of action and design of therapeutic agents Acta Crystallographica Section A. 75. DOI: 10.1107/S0108767319099409 |
0.342 |
|
| 2018 |
Garcellano RC, Moinuddin SGA, Young RP, Zhou M, Bowden ME, Renslow RS, Yesiltepe Y, Thomas DG, Colby SM, Chouinard CD, Nagy G, Attah IK, Ibrahim YM, Ma R, Franzblau SG, et al. Isolation of Tryptanthrin and Reassessment of Evidence for Its Isobaric Isostere Wrightiadione in Plants of the Wrightia Genus. Journal of Natural Products. PMID 30295480 DOI: 10.1021/Acs.Jnatprod.8B00567 |
0.398 |
|
| 2018 |
Lemieux MR, Siricilla S, Mitachi K, Eslamimehr S, Wang Y, Yang D, Pressly JD, Kong Y, Park F, Franzblau SG, Kurosu M. An antimycobacterial pleuromutilin analogue effective against dormant bacilli. Bioorganic & Medicinal Chemistry. PMID 30145051 DOI: 10.1016/J.Bmc.2018.07.034 |
0.44 |
|
| 2018 |
Palos I, Luna-Herrera J, Lara-Ramírez EE, Loera-Piedra A, Fernández-Ramírez E, Aguilera-Arreola MG, Paz-González AD, Monge A, Wan B, Franzblau S, Rivera G. Anti- Activity of Esters of Quinoxaline 1,4-Di--Oxide. Molecules (Basel, Switzerland). 23. PMID 29914062 DOI: 10.3390/Molecules23061453 |
0.408 |
|
| 2018 |
Schmidt U, Theumer G, Jäger A, Kataeva O, Wan B, Franzblau SG, Knölker HJ. Synthesis and Activity against of Olivacine and Oxygenated Derivatives. Molecules (Basel, Switzerland). 23. PMID 29890747 DOI: 10.3390/Molecules23061402 |
0.339 |
|
| 2018 |
Choules MP, Klein LL, Lankin DC, McAlpine JB, Cho SH, Cheng J, Lee H, Suh JW, Jaki BU, Franzblau SG, Pauli GF. Residual Complexity Does Impact Organic Chemistry and Drug Discovery: The Case of Rufomyazine and Rufomycin. The Journal of Organic Chemistry. PMID 29792329 DOI: 10.1021/Acs.Joc.8B00988 |
0.39 |
|
| 2018 |
Meta E, Brullo C, Tonelli M, Franzblau SG, Wang Y, Ma R, Baojie W, Orena BS, Pasca MR, Bruno O. Pyrazole and imidazo[1,2-b]pyrazole derivatives as new potential anti-tuberculosis agents. Medicinal Chemistry (Shariqah (United Arab Emirates)). PMID 29792151 DOI: 10.2174/1573406414666180524084023 |
0.446 |
|
| 2018 |
Sutherland HS, Tong AST, Choi PJ, Conole D, Blaser A, Franzblau SG, Cooper CB, Upton AM, Lotlikar MU, Denny WA, Palmer BD. Structure-activity relationships for analogs of the tuberculosis drug bedaquiline with the naphthalene unit replaced by bicyclic heterocycles. Bioorganic & Medicinal Chemistry. PMID 29482950 DOI: 10.1016/J.Bmc.2018.02.026 |
0.492 |
|
| 2018 |
Harbut MB, Liu R, Yang B, Yano T, Vilcheze C, Lockner J, Guo H, Franzblau SG, Petrassi M, Jacobs WR, Rubin H, Chatterjee AK, Wang F. Small molecules targeting Mycobacterium tuberculosis type II NADH dehydrogenase with antimycobacterial activity. Angewandte Chemie (International Ed. in English). PMID 29388301 DOI: 10.1002/Anie.201800260 |
0.45 |
|
| 2017 |
Lu X, Hu X, Liu Z, Zhang T, Wang R, Wan B, Franzblau SG, You Q. Benzylsulfanyl benzo-heterocycle amides and hydrazones as new agents against drug-susceptible and resistant . Medchemcomm. 8: 1303-1306. PMID 30108841 DOI: 10.1039/C7Md00146K |
0.51 |
|
| 2017 |
Thompson AM, Bonnet M, Lee HH, Franzblau SG, Wan B, Wong GS, Cooper CB, Denny WA. Antitubercular Nitroimidazoles Revisited: Synthesis and Activity of the Authentic 3-Nitro Isomer of Pretomanid. Acs Medicinal Chemistry Letters. 8: 1275-1280. PMID 29259747 DOI: 10.1021/Acsmedchemlett.7B00356 |
0.406 |
|
| 2017 |
Macabeo APG, Letada AG, Budde S, Faderl C, Dahse HM, Franzblau SG, Alejandro GJD, Pierens GK, Garson MJ. Antitubercular and Cytotoxic Chlorinated seco-Cyclohexenes from Uvaria alba. Journal of Natural Products. 80: 3319-3323. PMID 29172496 DOI: 10.1021/Acs.Jnatprod.7B00679 |
0.385 |
|
| 2017 |
Choi PJ, Sutherland HS, Tong AST, Blaser A, Franzblau SG, Cooper CB, Lotlikar MU, Upton AM, Guillemont J, Motte M, Queguiner L, Andries K, Van den Broeck W, Denny WA, Palmer BD. Synthesis and evaluation of analogues of the tuberculosis drug bedaquiline containing heterocyclic B-ring units. Bioorganic & Medicinal Chemistry Letters. PMID 29107541 DOI: 10.1016/J.Bmcl.2017.10.042 |
0.446 |
|
| 2017 |
Tong AST, Choi PJ, Blaser A, Sutherland HS, Tsang SKY, Guillemont J, Motte M, Cooper CB, Andries K, Van den Broeck W, Franzblau SG, Upton AM, Denny WA, Palmer BD, Conole D. 6-Cyano Analogues of Bedaquiline as Less Lipophilic and Potentially Safer Diarylquinolines for Tuberculosis. Acs Medicinal Chemistry Letters. 8: 1019-1024. PMID 29057044 DOI: 10.1021/Acsmedchemlett.7B00196 |
0.493 |
|
| 2017 |
Fernandes GFDS, De Souza PC, Moreno-Viguri E, Santivañez-Veliz M, Paucar R, Pérez-Silanes S, Chegaev K, Guglielmo S, Lazzarato L, Fruttero R, Man Chin C, Da Silva PB, Chorilli M, Solcia MC, Ribeiro CM, ... ... Franzblau SG, et al. Design, Synthesis and Characterization of N-oxide-containing Heterocycles with In vivo Sterilizing Antitubercular Activity. Journal of Medicinal Chemistry. PMID 28968083 DOI: 10.1021/Acs.Jmedchem.7B01332 |
0.439 |
|
| 2017 |
Warit S, Rukseree K, Prammananan T, Hongmanee P, Billamas P, Jaitrong S, Chaiprasert A, Jaki BU, Pauli GF, Franzblau SG, Palittapongarnpim P. In Vitro Activities of Enantiopure and Racemic 1'-Acetoxychavicol Acetate against Clinical Isolates of Mycobacterium tuberculosis. Scientia Pharmaceutica. 85. PMID 28927024 DOI: 10.3390/Scipharm85030032 |
0.459 |
|
| 2017 |
Brengel C, Thomann A, Schifrin A, Allegretta G, Kamal AAM, Haupenthal J, Schnorr I, Cho SH, Franzblau SG, Empting M, Eberhard J, Hartmann RW. Biophysical Screening of a Focused Library for the Discovery of CYP121 Inhibitors as Novel Antimycobacterials. Chemmedchem. PMID 28815923 DOI: 10.1002/Cmdc.201700363 |
0.424 |
|
| 2017 |
Liu R, Lyu X, Hsu MH, Vilcheze C, Franzblau SG, Jacobs WR, Besra GS, Johnson EF, Fütterer K, Wang F. Determinants of the Inhibition of DprE1 and CYP2C9 by Antitubercular Thiophenes. Angewandte Chemie (International Ed. in English). PMID 28815830 DOI: 10.1002/Anie.201707324 |
0.462 |
|
| 2017 |
Wavhale RD, Martis EAF, Ambre PK, Wan B, Franzblau SG, Iyer KR, Raikuvar K, Macegoniuk K, Berlicki Ł, Nandan SR, Coutinho EC. Discovery of new leads against Mycobacterium tuberculosis using scaffold hopping and shape based similarity. Bioorganic & Medicinal Chemistry. PMID 28778369 DOI: 10.1016/J.Bmc.2017.07.034 |
0.456 |
|
| 2017 |
Jiménez-Romero C, Rode JE, Pérez YM, Franzblau SG, Rodríguez AD. Exploring the Sponge Consortium Plakortis symbiotica-Xestospongia deweerdtae as a Potential Source of Antimicrobial Compounds and Probing the Pharmacophore for Antituberculosis Activity of Smenothiazole A by Diverted Total Synthesis. Journal of Natural Products. PMID 28742349 DOI: 10.1021/Acs.Jnatprod.7B00300 |
0.473 |
|
| 2017 |
Gomes MN, Braga RC, Grzelak EM, Neves BJ, Muratov E, Ma R, Klein LL, Cho S, Oliveira GR, Franzblau SG, Andrade CH. QSAR-driven design, synthesis and discovery of potent chalcone derivatives with antitubercular activity. European Journal of Medicinal Chemistry. 137: 126-138. PMID 28582669 DOI: 10.1016/J.Ejmech.2017.05.026 |
0.514 |
|
| 2017 |
Thompson AM, Blaser A, Palmer BD, Anderson RF, Shinde SS, Launay D, Chatelain E, Maes L, Franzblau SG, Wan B, Wang Y, Ma Z, Denny WA. 6-Nitro-2,3-dihydroimidazo[2,1-b][1,3]thiazoles: Facile synthesis and comparative appraisal against tuberculosis and neglected tropical diseases. Bioorganic & Medicinal Chemistry Letters. PMID 28462832 DOI: 10.1016/J.Bmcl.2017.03.069 |
0.43 |
|
| 2017 |
Thompson AM, O'Connor PD, Marshall AJ, Yardley V, Maes L, Gupta S, Launay D, Braillard S, Chatelain E, Franzblau SG, Wan B, Wang Y, Ma Z, Cooper CB, Denny WA. 7-Substituted 2-nitro-5,6-dihydroimidazo[2,1-b][1,3]oxazines: novel antitubercular agents lead to a new preclinical candidate for visceral leishmaniasis. Journal of Medicinal Chemistry. PMID 28459575 DOI: 10.1021/Acs.Jmedchem.7B00034 |
0.345 |
|
| 2017 |
Gomes MN, Alcântara LM, Neves BJ, Melo-Filho CC, Freitas-Junior LH, Moraes CB, Ma R, Franzblau SG, Muratov E, Andrade CH. Computer-aided discovery of two novel chalcone-like compounds active and selective against Leishmania infantum. Bioorganic & Medicinal Chemistry Letters. PMID 28434763 DOI: 10.1016/J.Bmcl.2017.04.010 |
0.379 |
|
| 2016 |
Börger C, Brütting C, Julich-Gruner KK, Hesse R, Kumar VP, Kutz SK, Rönnefahrt M, Thomas C, Wan B, Franzblau SG, Knölker HJ. Anti-tuberculosis activity and structure-activity relationships of oxygenated tricyclic carbazole alkaloids and synthetic derivatives. Bioorganic & Medicinal Chemistry. PMID 28094223 DOI: 10.1016/J.Bmc.2016.12.038 |
0.478 |
|
| 2016 |
Cortesia C, Bello T, Lopez G, Franzblau S, de Waard J, Takiff H. Use of green fluorescent protein labeled non-tuberculous mycobacteria to evaluate the activity quaternary ammonium compound disinfectants and antibiotics. Brazilian Journal of Microbiology : [Publication of the Brazilian Society For Microbiology]. PMID 27789202 DOI: 10.1016/J.Bjm.2016.09.009 |
0.365 |
|
| 2016 |
Velappan AB, Charan Raja MR, Datta D, Tsai YT, Halloum I, Wan B, Kremer L, Gramajo H, Franzblau SG, Kar Mahapatra S, Debnath J. Attenuation of Mycobacterium species through direct and macrophage mediated pathway by unsymmetrical diaryl urea. European Journal of Medicinal Chemistry. 125: 825-841. PMID 27750200 DOI: 10.1016/J.Ejmech.2016.09.083 |
0.423 |
|
| 2016 |
Moraski GC, Seeger N, Miller PA, Oliver AG, Boshoff HI, Cho S, Mulugeta S, Anderson JR, Franzblau SG, Miller MJ. Arrival of Imidazo[2,1-b]thiazole-5-carboxamides: Potent Anti-tuberculosis Agents That Target QcrB. Acs Infectious Diseases. 2: 393-398. PMID 27627627 DOI: 10.1021/Acsinfecdis.5B00154 |
0.515 |
|
| 2016 |
Mitachi K, Siricilla S, Yang D, Kong Y, Skorupinska-Tudek K, Swiezewska E, Franzblau SG, Kurosu M. Fluorescence-based assay for polyprenyl phosphate-GlcNAc-1-phosphate transferase (WecA) and identification of novel antimycobacterial WecA inhibitors. Analytical Biochemistry. PMID 27530653 DOI: 10.1016/J.Ab.2016.08.008 |
0.377 |
|
| 2016 |
Palencia A, Li X, Bu W, Choi W, Ding CZ, Easom EE, Feng L, Hernandez V, Houston P, Liu L, Meewan M, Mohan M, Rock FL, Sexton H, Zhang S, ... ... Franzblau SG, et al. Discovery of novel oral protein synthesis inhibitors of Mycobacterium tuberculosis that target leucyl-tRNA synthetase. Antimicrobial Agents and Chemotherapy. PMID 27503647 DOI: 10.1128/Aac.01339-16 |
0.458 |
|
| 2016 |
Grzelak EM, Hwang C, Cai G, Nam JW, Choules MP, Gao W, Lankin DC, McAlpine JB, Mulugeta SG, Napolitano JG, Suh JW, Yang SH, Cheng J, Lee H, Kim JY, ... ... Franzblau SG, et al. Bioautography with TLC-MS/NMR for Rapid Discovery of Anti-tuberculosis Lead Compounds from Natural Sources. Acs Infectious Diseases. 2: 294-301. PMID 27478868 DOI: 10.1021/Acsinfecdis.5B00150 |
0.469 |
|
| 2016 |
Segretti ND, Simões CK, Corrêa MF, Felli VM, Miyata M, Cho SH, Franzblau SG, Fernandes JP. Antimycobacterial activity of pyrazinoate prodrugs in replicating and non-replicating Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland). 99: 11-6. PMID 27449999 DOI: 10.1016/J.Tube.2016.04.002 |
0.452 |
|
| 2016 |
Moraski GC, Cheng Y, Cho S, Cramer JW, Godfrey A, Masquelin T, Franzblau SG, Miller MJ, Schorey J. Imidazo[1,2-a]pyridine-3-carboxamides are Active Antimicrobial Agents of Mycobacterium avium Infection In Vivo. Antimicrobial Agents and Chemotherapy. PMID 27216051 DOI: 10.1128/Aac.00618-16 |
0.39 |
|
| 2016 |
Guan YF, Song X, Qiu MH, Luo SH, Wan BJ, Van Hung N, Cuong NM, Soejarto DD, Fong HH, Franzblau SG, Li SH, He ZD, Zhang HJ. Bioassay-Guided Isolation and Structural Modification of the Anti-TB Resorcinols from Ardisia gigantifolia. Chemical Biology & Drug Design. PMID 26992112 DOI: 10.1111/Cbdd.12756 |
0.516 |
|
| 2016 |
Tiwari R, Miller PA, Chiarelli LR, Mori G, Šarkan M, Centárová I, Cho S, Mikušová K, Franzblau SG, Oliver AG, Miller MJ. Design, Syntheses, and Anti-TB Activity of 1,3-Benzothiazinone Azide and Click Chemistry Products Inspired by BTZ043. Acs Medicinal Chemistry Letters. 7: 266-70. PMID 26985313 DOI: 10.1021/Acsmedchemlett.5B00424 |
0.466 |
|
| 2016 |
Majewski MW, Tiwari R, Miller PA, Cho S, Franzblau SG, Miller MJ. Design, syntheses, and anti-tuberculosis activities of conjugates of piperazino-1,3-benzothiazin-4-ones (pBTZs) with 2,7-dimethylimidazo [1,2-a]pyridine-3-carboxylic acids and 7-phenylacetyl cephalosporins. Bioorganic & Medicinal Chemistry Letters. PMID 26951749 DOI: 10.1016/J.Bmcl.2016.02.076 |
0.486 |
|
| 2016 |
Majewski MW, Watson KD, Cho S, Miller PA, Franzblau SG, Miller MJ. Syntheses and Biological Evaluations of Highly Functionalized Hydroxamate Containing and N-Methylthio Monobactams as Anti-Tuberculosis and β-Lactamase Inhibitory Agents. Medchemcomm. 7: 141-147. PMID 26918106 DOI: 10.1039/C5Md00340G |
0.446 |
|
| 2016 |
Thompson AM, O'Connor PD, Blaser A, Yardley V, Maes L, Gupta S, Launay D, Martin D, Franzblau SG, Wan B, Wang Y, Ma Z, Denny WA. Repositioning antitubercular 6-nitro-2,3-dihydroimidazo[2,1-b][1,3]oxazoles for neglected tropical diseases: structure-activity studies on a preclinical candidate for visceral leishmaniasis. Journal of Medicinal Chemistry. PMID 26901446 DOI: 10.1021/Acs.Jmedchem.5B01699 |
0.379 |
|
| 2016 |
Nieves K, Prudhomme J, Le Roch KG, Franzblau SG, Rodríguez AD. Natural product-based synthesis of novel anti-infective isothiocyanate- and isoselenocyanate-functionalized amphilectane diterpenes. Bioorganic & Medicinal Chemistry Letters. 26: 854-7. PMID 26748697 DOI: 10.1016/J.Bmcl.2015.12.080 |
0.432 |
|
| 2016 |
Majewski MW, Watson KD, Cho S, Miller PA, Franzblau SG, Miller MJ. Syntheses and biological evaluations of highly functionalized hydroxamate containing and N-methylthio monobactams as anti-tuberculosis and β-lactamase inhibitory agents Medchemcomm. 7: 141-147. DOI: 10.1039/C5Md90052B |
0.376 |
|
| 2016 |
Grzelak EM, Hwang C, Cai G, Nam JW, Choules MP, Gao W, Lankin DC, McAlpine JB, Mulugeta SG, Napolitano JG, Suh JW, Yang SH, Cheng J, Lee H, Kim JY, ... ... Franzblau SG, et al. Bioautography with TLC-MS/NMR for Rapid Discovery of Anti-tuberculosis Lead Compounds from Natural Sources Acs Infectious Diseases. 2: 294-301. DOI: 10.1021/acsinfecdis.5b00150 |
0.609 |
|
| 2016 |
Segretti ND, Simões CK, Corrêa MF, Felli VMA, Miyata M, Cho SH, Franzblau SG, Fernandes JPDS. Antimycobacterial activity of pyrazinoate prodrugs in replicating and non-replicating Mycobacterium tuberculosis Tuberculosis. 99: 11-16. DOI: 10.1016/j.tube.2016.04.002 |
0.344 |
|
| 2015 |
Mullowney MW, Hwang CH, Newsome AG, Wei X, Tanouye U, Wan B, Carlson S, Barranis NJ, hAinmhire E, Chen WL, Krishnamoorthy K, White J, Blair R, Lee H, Burdette JE, ... ... Franzblau SG, et al. Diaza-anthracene Antibiotics from a Freshwater-Derived Actinomycete with Selective Antibacterial Activity toward Mycobacterium tuberculosis. Acs Infectious Diseases. 1: 168-174. PMID 26594660 DOI: 10.1021/Acsinfecdis.5B00005 |
0.657 |
|
| 2015 |
Penta A, Franzblau S, Wan B, Murugesan S. Design, synthesis and evaluation of diarylpiperazine derivatives as potent anti-tubercular agents. European Journal of Medicinal Chemistry. 105: 238-44. PMID 26498570 DOI: 10.1016/J.Ejmech.2015.10.024 |
0.433 |
|
| 2015 |
Avilés E, Prudhomme J, Le Roch KG, Franzblau SG, Chandrasena K, Mayer AM, Rodríguez AD. Synthesis and preliminary biological evaluation of a small library of hybrid compounds based on Ugi isocyanide multicomponent reactions with a marine natural product scaffold. Bioorganic & Medicinal Chemistry Letters. 25: 5339-43. PMID 26421992 DOI: 10.1016/J.Bmcl.2015.09.033 |
0.421 |
|
| 2015 |
Gutka HJ, Wang Y, Franzblau SG, Movahedzadeh F. glpx Gene in Mycobacterium tuberculosis Is Required for In Vitro Gluconeogenic Growth and In Vivo Survival. Plos One. 10: e0138436. PMID 26397812 DOI: 10.1371/Journal.Pone.0138436 |
0.781 |
|
| 2015 |
Thompson AM, Blaser A, Palmer BD, Franzblau SG, Wan B, Wang Y, Ma Z, Denny WA. Biarylmethoxy 2-nitroimidazooxazine antituberculosis agents: Effects of proximal ring substitution and linker reversal on metabolism and efficacy. Bioorganic & Medicinal Chemistry Letters. PMID 26253632 DOI: 10.1016/J.Bmcl.2015.07.084 |
0.337 |
|
| 2015 |
Pieroni M, Wan B, Zuliani V, Franzblau SG, Costantino G, Rivara M. Discovery of antitubercular 2,4-diphenyl-1H-imidazoles from chemical library repositioning and rational design. European Journal of Medicinal Chemistry. 100: 44-49. PMID 26071857 DOI: 10.1016/J.Ejmech.2015.05.048 |
0.481 |
|
| 2015 |
Majewski MW, Cho S, Miller PA, Franzblau SG, Miller MJ. Syntheses and evaluation of substituted aromatic hydroxamates and hydroxamic acids that target Mycobacterium tuberculosis. Bioorganic & Medicinal Chemistry Letters. PMID 26037320 DOI: 10.1016/J.Bmcl.2015.04.099 |
0.504 |
|
| 2015 |
Luo S, Kang HS, Krunic A, Chen WL, Yang J, Woodard JL, Fuchs JR, Hyun Cho S, Franzblau SG, Swanson SM, Orjala J. Trichormamides C and D, antiproliferative cyclic lipopeptides from the cultured freshwater cyanobacterium cf. Oscillatoria sp. UIC 10045. Bioorganic & Medicinal Chemistry. 23: 3153-62. PMID 26001342 DOI: 10.1016/J.Bmc.2015.04.073 |
0.326 |
|
| 2015 |
Moraski GC, Miller PA, Bailey MA, Ollinger J, Parish T, Boshoff HI, Cho S, Anderson JR, Mulugeta S, Franzblau SG, Miller MJ. Putting Tuberculosis (TB) To Rest: Transformation of the Sleep Aid, Ambien, and "Anagrams" Generated Potent Antituberculosis Agents. Acs Infectious Diseases. 1: 85-90. PMID 25984566 DOI: 10.1021/Id500008T |
0.452 |
|
| 2015 |
Cho S, Lee HS, Franzblau S. Microplate Alamar Blue Assay (MABA) and Low Oxygen Recovery Assay (LORA) for Mycobacterium tuberculosis. Methods in Molecular Biology (Clifton, N.J.). 1285: 281-92. PMID 25779323 DOI: 10.1007/978-1-4939-2450-9_17 |
0.448 |
|
| 2015 |
Tiwari R, Miller PA, Cho S, Franzblau SG, Miller MJ. Syntheses and Antituberculosis Activity of 1,3-Benzothiazinone Sulfoxide and Sulfone Derived from BTZ043. Acs Medicinal Chemistry Letters. 6: 128-33. PMID 25699139 DOI: 10.1021/Ml5003458 |
0.426 |
|
| 2015 |
Gao W, Kim JY, Anderson JR, Akopian T, Hong S, Jin YY, Kandror O, Kim JW, Lee IA, Lee SY, McAlpine JB, Mulugeta S, Sunoqrot S, Wang Y, Yang SH, ... ... Franzblau SG, et al. The cyclic peptide ecumicin targeting ClpC1 is active against Mycobacterium tuberculosis in vivo. Antimicrobial Agents and Chemotherapy. 59: 880-9. PMID 25421483 DOI: 10.1128/Aac.04054-14 |
0.471 |
|
| 2015 |
Upton AM, Cho S, Yang TJ, Kim Y, Wang Y, Lu Y, Wang B, Xu J, Mdluli K, Ma Z, Franzblau SG. In vitro and in vivo activities of the nitroimidazole TBA-354 against Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy. 59: 136-44. PMID 25331696 DOI: 10.1128/Aac.03823-14 |
0.474 |
|
| 2015 |
Siricilla S, Mitachi K, Wan B, Franzblau SG, Kurosu M. Discovery of a capuramycin analog that kills nonreplicating Mycobacterium tuberculosis and its synergistic effects with translocase I inhibitors. The Journal of Antibiotics. 68: 271-8. PMID 25269459 DOI: 10.1038/Ja.2014.133 |
0.417 |
|
| 2015 |
Lu X, Tang J, You Q, Wan B, Franzblau SG. Design, synthesis and antitubercular evaluation of new 2-amino-5-(4-(benzyloxy)benzyl)thiophene-3-carboxylic acid derivatives. Part 3 Letters in Drug Design and Discovery. 12: 29-37. DOI: 10.2174/1570180811666140812231321 |
0.404 |
|
| 2015 |
Yu Y, Chen S, Cho S, Nam J, Grzelak E, McAlpine J, Jaki B, Choules M, Kim J, Cheng J, Yang S, Lee H, Suh J, Franzblau S, Pauli G. Rufomycins – Actinomycete peptides with potent anti-TB activity Planta Medica. 81. DOI: 10.1055/S-0035-1556406 |
0.37 |
|
| 2015 |
Mullowney M, hAinmhire E, Tanouye U, Wan B, Cho S, Franzblau S, Burdette J, Cuong P, Murphy B. A novel pimarane diterpene and cytotoxic angucyclines from a marine-derived actinomycete in Vietnam Planta Medica. 81. DOI: 10.1055/S-0035-1556362 |
0.335 |
|
| 2015 |
Grzelak E, Liu Y, Nam J, Friesen J, Chen S, Lankin D, McAlpine J, Suh J, Yang S, Cheng J, Lee H, Kim J, Cho S, Pauli G, Franzblau S, et al. TLC-bioautography linked with guess: A truely targeted active compound isolation process Planta Medica. 81. DOI: 10.1055/S-0035-1556275 |
0.406 |
|
| 2015 |
Grzelak E, Choules M, Hwang C, Nam J, Yu Y, Cai G, Gao W, Lankin D, McAlpine J, Mulugeta S, Napolitano J, Suh J, Yang S, Cheng J, Lee H, ... ... Franzblau S, et al. (HP)TLC-bioautography-MS/NMR – A new tool for the search of anti-tuberculosis lead compounds Planta Medica. 81. DOI: 10.1055/S-0035-1556192 |
0.601 |
|
| 2015 |
Choules M, Yu Y, Cho S, Anderson J, Gao W, Klein L, Lankin D, Kim J, Cheng J, Yang S, Lee H, Suh J, Franzblau S, Pauli G. A rufomycin analogue is an anti-tuberculosis drug lead targeting CLPC1 with no cross resistance to ecumicin Planta Medica. 81. DOI: 10.1055/S-0035-1556165 |
0.403 |
|
| 2014 |
Gao W, Kim JY, Chen SN, Cho SH, Choi J, Jaki BU, Jin YY, Lankin DC, Lee JE, Lee SY, McAlpine JB, Napolitano JG, Franzblau SG, Suh JW, Pauli GF. Discovery and characterization of the tuberculosis drug lead ecumicin. Organic Letters. 16: 6044-7. PMID 25409285 DOI: 10.1021/Ol5026603 |
0.422 |
|
| 2014 |
MacAbeo APG, Martinez FPA, Kurtán T, Tóth L, Mándi A, Schmidt S, Heilmann J, Alejandro GJD, Knorn M, Dahse HM, Franzblau SG. Tetrahydroxanthene-1,3(2 H)-dione derivatives from Uvaria valderramensis Journal of Natural Products. 77: 2711-2715. PMID 25372601 DOI: 10.1021/Np500538C |
0.342 |
|
| 2014 |
Luo S, Kang HS, Krunic A, Chlipala GE, Cai G, Chen WL, Franzblau SG, Swanson SM, Orjala J. Carbamidocyclophanes F and G with Anti-Mycobacterium tuberculosis Activity from the Cultured Freshwater Cyanobacterium Nostoc sp. Tetrahedron Letters. 55: 686-689. PMID 25225453 DOI: 10.1016/J.Tetlet.2013.11.112 |
0.378 |
|
| 2014 |
Li W, Upadhyay A, Fontes FL, North EJ, Wang Y, Crans DC, Grzegorzewicz AE, Jones V, Franzblau SG, Lee RE, Crick DC, Jackson M. Novel insights into the mechanism of inhibition of MmpL3, a target of multiple pharmacophores in Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy. 58: 6413-23. PMID 25136022 DOI: 10.1128/Aac.03229-14 |
0.44 |
|
| 2014 |
Moraski GC, Oliver AG, Markley LD, Cho S, Franzblau SG, Miller MJ. Scaffold-switching: an exploration of 5,6-fused bicyclic heteroaromatics systems to afford antituberculosis activity akin to the imidazo[1,2-a]pyridine-3-carboxylates. Bioorganic & Medicinal Chemistry Letters. 24: 3493-8. PMID 24909079 DOI: 10.1016/J.Bmcl.2014.05.062 |
0.469 |
|
| 2014 |
Tiwari R, Möllmann U, Cho S, Franzblau SG, Miller PA, Miller MJ. Design and Syntheses of Anti-Tuberculosis Agents Inspired by BTZ043 Using a Scaffold Simplification Strategy. Acs Medicinal Chemistry Letters. 5: 587-91. PMID 24900885 DOI: 10.1021/Ml500039G |
0.49 |
|
| 2014 |
Lirio SB, Macabeo AP, Paragas EM, Knorn M, Kohls P, Franzblau SG, Wang Y, Aguinaldo MA. Antitubercular constituents from Premna odorata Blanco. Journal of Ethnopharmacology. 154: 471-4. PMID 24768632 DOI: 10.1016/J.Jep.2014.04.015 |
0.349 |
|
| 2014 |
Schinkovitz A, Kaur A, Urban E, Zehl M, Páchniková G, Wang Y, Kretschmer N, Slaninová I, Pauli GF, Franzblau SG, Krupitza G, Bauer R, Kopp B. Cytotoxic constituents from Lobaria scrobiculata and a comparison of two bioassays for their evaluation. Journal of Natural Products. 77: 1069-73. PMID 24725159 DOI: 10.1021/Np4008574 |
0.364 |
|
| 2014 |
Ramos Alvarenga RF, Wan B, Inui T, Franzblau SG, Pauli GF, Jaki BU. Airborne antituberculosis activity of Eucalyptus citriodora essential oil. Journal of Natural Products. 77: 603-10. PMID 24641242 DOI: 10.1021/Np400872M |
0.462 |
|
| 2014 |
Elkington BG, Sydara K, Newsome A, Hwang CH, Lankin DC, Simmler C, Napolitano JG, Ree R, Graham JG, Gyllenhaal C, Bouamanivong S, Souliya O, Pauli GF, Franzblau SG, Soejarto DD. New finding of an anti-TB compound in the genus Marsypopetalum (Annonaceae) from a traditional herbal remedy of Laos. Journal of Ethnopharmacology. 151: 903-11. PMID 24333958 DOI: 10.1016/J.Jep.2013.11.057 |
0.612 |
|
| 2014 |
Pieroni M, Wan B, Cho S, Franzblau SG, Costantino G. Design, synthesis and investigation on the structure-activity relationships of N-substituted 2-aminothiazole derivatives as antitubercular agents. European Journal of Medicinal Chemistry. 72: 26-34. PMID 24333612 DOI: 10.1016/J.Ejmech.2013.11.007 |
0.503 |
|
| 2014 |
Lv W, Banerjee B, Molland KL, Seleem MN, Ghafoor A, Hamed MI, Wan B, Franzblau SG, Mesecar AD, Cushman M. Synthesis of 3-(3-aryl-pyrrolidin-1-yl)-5-aryl-1,2,4-triazines that have antibacterial activity and also inhibit inorganic pyrophosphatase. Bioorganic & Medicinal Chemistry. 22: 406-18. PMID 24315189 DOI: 10.1016/J.Bmc.2013.11.011 |
0.449 |
|
| 2014 |
Klein LL, Petukhova V, Wan B, Wang Y, Santasiero BD, Lankin DC, Pauli GF, Franzblau SG. A novel indigoid anti-tuberculosis agent. Bioorganic & Medicinal Chemistry Letters. 24: 268-70. PMID 24314672 DOI: 10.1016/J.Bmcl.2013.11.024 |
0.473 |
|
| 2014 |
Grzelak E, Choules M, Hwang C, Nam J, Mulugeta S, McAlpine J, Cai G, Gao W, Lankin D, Napolitano J, Suh J, Yang S, Cheng J, Kim J, Cho S, ... ... Franzblau S, et al. A new concept for anti-tuberculosis drug discovery Planta Medica. 80. DOI: 10.1055/S-0034-1382341 |
0.603 |
|
| 2014 |
Siricilla S, Mitachi K, Wan B, Franzblau SG, Kurosu M. Discovery of a capuramycin analog that kills nonreplicating Mycobacterium tuberculosis and its synergistic effects with translocase i inhibitors Journal of Antibiotics. 68: 271-278. DOI: 10.1038/ja.2014.133 |
0.319 |
|
| 2014 |
Ambre PK, Pissurlenkar RRS, Wavhale RD, Shaikh MS, Khedkar VM, Wan B, Franzblau SG, Coutinho EC. Design, synthesis, and evaluation of 4-(substituted)phenyl-2-thioxo-3,4- dihydro-1H-chromino[4,3-d]pyrimidin-5-one and 4-(substituted)phenyl-3,4-dihydro- 1H-chromino[4,3-d]pyrimidine-2,5-dione analogs as antitubercular agents Medicinal Chemistry Research. 23: 2564-2575. DOI: 10.1007/S00044-013-0850-7 |
0.4 |
|
| 2013 |
Cai G, Napolitano JG, McAlpine JB, Wang Y, Jaki BU, Suh JW, Yang SH, Lee IA, Franzblau SG, Pauli GF, Cho S. Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. Journal of Natural Products. 76: 2009-18. PMID 24224794 DOI: 10.1021/Np400145U |
0.47 |
|
| 2013 |
Hwang CH, Jaki BU, Klein LL, Lankin DC, McAlpine JB, Napolitano JG, Fryling NA, Franzblau SG, Cho SH, Stamets PE, Wang Y, Pauli GF. Chlorinated coumarins from the polypore mushroom Fomitopsis officinalis and their activity against Mycobacterium tuberculosis. Journal of Natural Products. 76: 1916-22. PMID 24087924 DOI: 10.1021/Np400497F |
0.64 |
|
| 2013 |
Schmidt AW, Choi TA, Theumer G, Franzblau SG, Knölker HJ. Inhibitory effect of oxygenated cholestan-3β-ol derivatives on the growth of Mycobacterium tuberculosis. Bioorganic & Medicinal Chemistry Letters. 23: 6111-3. PMID 24084159 DOI: 10.1016/J.Bmcl.2013.09.013 |
0.786 |
|
| 2013 |
Wijeratne EM, He H, Franzblau SG, Hoffman AM, Gunatilaka AA. Phomapyrrolidones A-C, antitubercular alkaloids from the endophytic fungus Phoma sp. NRRL 46751. Journal of Natural Products. 76: 1860-5. PMID 24079882 DOI: 10.1021/Np400391P |
0.317 |
|
| 2013 |
Grant SS, Kawate T, Nag PP, Silvis MR, Gordon K, Stanley SA, Kazyanskaya E, Nietupski R, Golas A, Fitzgerald M, Cho S, Franzblau SG, Hung DT. Identification of novel inhibitors of nonreplicating Mycobacterium tuberculosis using a carbon starvation model. Acs Chemical Biology. 8: 2224-34. PMID 23898841 DOI: 10.1021/Cb4004817 |
0.426 |
|
| 2013 |
Lauinger IL, Vivas L, Perozzo R, Stairiker C, Tarun A, Zloh M, Zhang X, Xu H, Tonge PJ, Franzblau SG, Pham DH, Esguerra CV, Crawford AD, Maes L, Tasdemir D. Potential of lichen secondary metabolites against Plasmodium liver stage parasites with FAS-II as the potential target. Journal of Natural Products. 76: 1064-70. PMID 23806111 DOI: 10.1021/Np400083K |
0.364 |
|
| 2013 |
Wang F, Sambandan D, Halder R, Wang J, Batt SM, Weinrick B, Ahmad I, Yang P, Zhang Y, Kim J, Hassani M, Huszar S, Trefzer C, Ma Z, Kaneko T, ... ... Franzblau S, et al. Identification of a small molecule with activity against drug-resistant and persistent tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. 110: E2510-7. PMID 23776209 DOI: 10.1073/Pnas.1309171110 |
0.459 |
|
| 2013 |
McClay K, Wan B, Wang Y, Cho S, Yu J, Santarsiero B, Mehboob S, Johnson M, Franzblau S, Steffan R. A novel combinatorial biocatalytic approach for producing antibacterial compounds effective against Mycobacterium tuberculosis (TB). Applied Microbiology and Biotechnology. 97: 7151-63. PMID 23749163 DOI: 10.1007/S00253-013-5012-9 |
0.499 |
|
| 2013 |
Pavan FR, Poelhsitz GV, da Cunha LV, Barbosa MI, Leite SR, Batista AA, Cho SH, Franzblau SG, de Camargo MS, Resende FA, Varanda EA, Leite CQ. In vitro and in vivo activities of ruthenium(II) phosphine/diimine/picolinate complexes (SCAR) against Mycobacterium tuberculosis. Plos One. 8: e64242. PMID 23724039 DOI: 10.1371/Journal.Pone.0064242 |
0.437 |
|
| 2013 |
Ekins S, Reynolds RC, Franzblau SG, Wan B, Freundlich JS, Bunin BA. Enhancing hit identification in Mycobacterium tuberculosis drug discovery using validated dual-event Bayesian models. Plos One. 8: e63240. PMID 23667592 DOI: 10.1371/Journal.Pone.0063240 |
0.435 |
|
| 2013 |
Cai G, Pauli GF, Wang Y, Jaki BU, Franzblau SG. Rapid determination of growth inhibition of Mycobacterium tuberculosis by GC-MS/MS quantitation of tuberculostearic acid. Tuberculosis (Edinburgh, Scotland). 93: 322-9. PMID 23454100 DOI: 10.1016/J.Tube.2012.12.004 |
0.422 |
|
| 2013 |
Poce G, Bates RH, Alfonso S, Cocozza M, Porretta GC, Ballell L, Rullas J, Ortega F, De Logu A, Agus E, La Rosa V, Pasca MR, De Rossi E, Wae B, Franzblau SG, et al. Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection. Plos One. 8: e56980. PMID 23437287 DOI: 10.1371/Journal.Pone.0056980 |
0.452 |
|
| 2013 |
Mehnaz S, Saleem RS, Yameen B, Pianet I, Schnakenburg G, Pietraszkiewicz H, Valeriote F, Josten M, Sahl HG, Franzblau SG, Gross H. Lahorenoic acids A-C, ortho-dialkyl-substituted aromatic acids from the biocontrol strain Pseudomonas aurantiaca PB-St2. Journal of Natural Products. 76: 135-41. PMID 23402329 DOI: 10.1021/Np3005166 |
0.347 |
|
| 2013 |
Hwang JM, Oh T, Kaneko T, Upton AM, Franzblau SG, Ma Z, Cho SN, Kim P. Design, synthesis, and structure-activity relationship studies of tryptanthrins as antitubercular agents. Journal of Natural Products. 76: 354-67. PMID 23360475 DOI: 10.1021/Np3007167 |
0.505 |
|
| 2013 |
Qiu F, Cai G, Jaki BU, Lankin DC, Franzblau SG, Pauli GF. Quantitative purity-activity relationships of natural products: the case of anti-tuberculosis active triterpenes from Oplopanax horridus. Journal of Natural Products. 76: 413-9. PMID 23356207 DOI: 10.1021/Np3007809 |
0.407 |
|
| 2013 |
Bukhari SN, Franzblau SG, Jantan I, Jasamai M. Current prospects of synthetic curcumin analogs and chalcone derivatives against mycobacterium tuberculosis. Medicinal Chemistry (ShāRiqah (United Arab Emirates)). 9: 897-903. PMID 23305394 DOI: 10.2174/1573406411309070002 |
0.432 |
|
| 2013 |
Pegan SD, Rukseree K, Capodagli GC, Baker EA, Krasnykh O, Franzblau SG, Mesecar AD. Active site loop dynamics of a class IIa fructose 1,6-bisphosphate aldolase from Mycobacterium tuberculosis. Biochemistry. 52: 912-25. PMID 23298222 DOI: 10.1021/Bi300928U |
0.343 |
|
| 2013 |
Wang F, Sambandan D, Halder R, Wang J, Batt SM, Weinrick B, Ahmad I, Yang P, Zhang Y, Kim J, Hassani M, Huszar S, Trefzer C, Ma Z, Kaneko T, ... ... Franzblau S, et al. Identification of a small molecule with activity against drug-resistant and persistent tuberculosis (vol 110, pg E2510, 2013) Proceedings of the National Academy of Sciences of the United States of America. 110: 15848-15848. DOI: 10.1073/Pnas.1315914110 |
0.362 |
|
| 2013 |
Wang F, Sambandan D, Halder R, Wang J, Batt SM, Weinrick B, Ahmad I, Yang P, Zhang Y, Kim J, Hassani M, Huszar S, Trefzer C, Ma Z, Kaneko T, ... ... Franzblau S, et al. Erratum: Identification of a small molecule with activity against drug-resistant and persistent tuberculosis (Proceedings of the National Academy of Sciences of the United States of America (2013) 27:110 (E2510-E2517)) Proceedings of the National Academy of Sciences of the United States of America. 110. DOI: 10.1073/Pnas.1314629110 |
0.354 |
|
| 2013 |
Hwang C, McAlpine J, Cai G, Cho S, Choules M, Gao W, Lankin D, Napolitano J, Suh J, Yang S, Cheng J, Kim J, Pauli G, Franzblau S, Jaki B. Bioautography for Rapid Detection, Isolation, and Identification of Anti-Tuberculosis Leads Planta Medica. 79. DOI: 10.1055/S-0033-1348649 |
0.609 |
|
| 2013 |
Elkington B, Sydara K, Newsome A, Hwang C, Simmler C, Lankin D, Souliya O, Franzblau S, Soejarto D. Bioactive Plants Used to Treat Symptoms of Tuberculosis from Traditional Medicines of Laos Planta Medica. 79. DOI: 10.1055/S-0033-1348592 |
0.552 |
|
| 2012 |
Tukulula M, Little S, Gut J, Rosenthal PJ, Wan B, Franzblau SG, Chibale K. The design, synthesis, in silico ADME profiling, antiplasmodial and antimycobacterial evaluation of new arylamino quinoline derivatives. European Journal of Medicinal Chemistry. 57: 259-67. PMID 23064162 DOI: 10.1016/J.Ejmech.2012.08.047 |
0.446 |
|
| 2012 |
Macabeo APG, Tudla FA, Krohn K, Franzblau SG. Antitubercular activity of the semi-polar extractives of Uvaria rufa Asian Pacific Journal of Tropical Medicine. 5: 777-780. PMID 23043915 DOI: 10.1016/S1995-7645(12)60142-4 |
0.375 |
|
| 2012 |
Brugarolas P, Movahedzadeh F, Wang Y, Zhang N, Bartek IL, Gao YN, Voskuil MI, Franzblau SG, He C. The oxidation-sensing regulator (MosR) is a new redox-dependent transcription factor in Mycobacterium tuberculosis. The Journal of Biological Chemistry. 287: 37703-12. PMID 22992749 DOI: 10.1074/Jbc.M112.388611 |
0.655 |
|
| 2012 |
Silveira GP, Ferreira M, Fernandes L, Moraski GC, Cho S, Hwang C, Franzblau SG, Sá MM. Allylic thiocyanates as a new class of antitubercular agents. Bioorganic & Medicinal Chemistry Letters. 22: 6486-9. PMID 22967767 DOI: 10.1016/J.Bmcl.2012.08.048 |
0.638 |
|
| 2012 |
Franzblau SG, DeGroote MA, Cho SH, Andries K, Nuermberger E, Orme IM, Mdluli K, Angulo-Barturen I, Dick T, Dartois V, Lenaerts AJ. Comprehensive analysis of methods used for the evaluation of compounds against Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland). 92: 453-88. PMID 22940006 DOI: 10.1016/J.Tube.2012.07.003 |
0.457 |
|
| 2012 |
Juárez-Hernández RE, Franzblau SG, Miller MJ. Syntheses of mycobactin analogs as potent and selective inhibitors of Mycobacterium tuberculosis. Organic & Biomolecular Chemistry. 10: 7584-93. PMID 22895786 DOI: 10.1039/C2Ob26077H |
0.454 |
|
| 2012 |
Tabarrini O, Sabatini S, Massari S, Pieroni M, Franzblau SG, Cecchetti V. 6-hydrogen-8-methylquinolones active against replicating and non-replicating Mycobacterium tuberculosis. Chemical Biology & Drug Design. 80: 781-6. PMID 22889240 DOI: 10.1111/Cbdd.12022 |
0.477 |
|
| 2012 |
Kim H, Lantvit D, Hwang CH, Kroll DJ, Swanson SM, Franzblau SG, Orjala J. Indole alkaloids from two cultured cyanobacteria, Westiellopsis sp. and Fischerella muscicola. Bioorganic & Medicinal Chemistry. 20: 5290-5. PMID 22863526 DOI: 10.1016/J.Bmc.2012.06.030 |
0.611 |
|
| 2012 |
Kunciw DL, Liechty JJ, Mitchell MO, Wan B, Franzblau SG. Structural requirements for the antitubercular quaternized triflupromazine pharmacophore. Bioorganic & Medicinal Chemistry Letters. 22: 5679-80. PMID 22850215 DOI: 10.1016/J.Bmcl.2012.06.095 |
0.424 |
|
| 2012 |
Macabeo APG, Avila JA, Alejandro GJD, Franzblau SG, Kouam SF, Hussain H, Krohn K. Villarinol, a new alkenoyloxyalkenol derivative from the endemic Philippine Rubiaceae species Villaria odorata Natural Product Communications. 7: 779-780. PMID 22816306 DOI: 10.1177/1934578X1200700622 |
0.416 |
|
| 2012 |
Macabeo APG, Gehle D, Krohn K, Franzblau SG, Aguinaldo AM. Photoactivated [3+2] addition of 6,7-seco -angustilobine B to fullerene [C60] Natural Product Communications. 7: 743-745. PMID 22816297 DOI: 10.1177/1934578X1200700613 |
0.36 |
|
| 2012 |
Inui T, Wang Y, Pro SM, Franzblau SG, Pauli GF. Unbiased evaluation of bioactive secondary metabolites in complex matrices. Fitoterapia. 83: 1218-25. PMID 22766306 DOI: 10.1016/J.Fitote.2012.06.012 |
0.448 |
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| 2012 |
Dulla B, Wan B, Franzblau SG, Kapavarapu R, Reiser O, Iqbal J, Pal M. Construction and functionalization of fused pyridine ring leading to novel compounds as potential antitubercular agents. Bioorganic & Medicinal Chemistry Letters. 22: 4629-35. PMID 22726932 DOI: 10.1016/J.Bmcl.2012.05.096 |
0.351 |
|
| 2012 |
Chopra S, Koolpe GA, Tambo-Ong AA, Matsuyama KN, Ryan KJ, Tran TB, Doppalapudi RS, Riccio ES, Iyer LV, Green CE, Wan B, Franzblau SG, Madrid PB. Discovery and optimization of benzotriazine di-N-oxides targeting replicating and nonreplicating Mycobacterium tuberculosis. Journal of Medicinal Chemistry. 55: 6047-60. PMID 22691154 DOI: 10.1021/Jm300123S |
0.439 |
|
| 2012 |
Ji C, Lin W, Moraski GC, Thanassi JA, Pucci MJ, Franzblau SG, Möllmann U, Miller MJ. Syntheses and biological studies of novel spiropiperazinyl oxazolidinone antibacterial agents using a spirocyclic diene derived acylnitroso Diels-Alder reaction. Bioorganic & Medicinal Chemistry. 20: 3422-8. PMID 22560837 DOI: 10.1016/J.Bmc.2012.04.026 |
0.388 |
|
| 2012 |
Shingnapurkar D, Dandawate P, Anson CE, Powell AK, Afrasiabi Z, Sinn E, Pandit S, Venkateswara Swamy K, Franzblau S, Padhye S. Synthesis and characterization of pyruvate-isoniazid analogs and their copper complexes as potential ICL inhibitors. Bioorganic & Medicinal Chemistry Letters. 22: 3172-6. PMID 22475559 DOI: 10.1016/J.Bmcl.2012.03.047 |
0.415 |
|
| 2012 |
Gill SK, Xu H, Kirchhoff PD, Cierpicki T, Turbiak AJ, Wan B, Zhang N, Peng KW, Franzblau SG, Garcia GA, Showalter HD. Structure-based design of novel benzoxazinorifamycins with potent binding affinity to wild-type and rifampin-resistant mutant Mycobacterium tuberculosis RNA polymerases. Journal of Medicinal Chemistry. 55: 3814-26. PMID 22452568 DOI: 10.1021/Jm201716N |
0.381 |
|
| 2012 |
Debnath J, Siricilla S, Wan B, Crick DC, Lenaerts AJ, Franzblau SG, Kurosu M. Discovery of selective menaquinone biosynthesis inhibitors against Mycobacterium tuberculosis. Journal of Medicinal Chemistry. 55: 3739-55. PMID 22449052 DOI: 10.1021/Jm201608G |
0.444 |
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| 2012 |
Moraski GC, Markley LD, Chang M, Cho S, Franzblau SG, Hwang CH, Boshoff H, Miller MJ. Generation and exploration of new classes of antitubercular agents: The optimization of oxazolines, oxazoles, thiazolines, thiazoles to imidazo[1,2-a]pyridines and isomeric 5,6-fused scaffolds. Bioorganic & Medicinal Chemistry. 20: 2214-20. PMID 22391032 DOI: 10.1016/J.Bmc.2012.02.025 |
0.65 |
|
| 2012 |
Lilienkampf A, Pieroni M, Franzblau SG, Bishai WR, Kozikowski AP. Derivatives of 3-isoxazolecarboxylic acid esters - a potent and selective compound class against replicating and nonreplicating Mycobacterium tuberculosis Current Topics in Medicinal Chemistry. 12: 729-734. PMID 22283815 DOI: 10.2174/156802612799984544 |
0.518 |
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| 2012 |
Lu X, Liu X, Wan B, Franzblau SG, Chen L, Zhou C, You Q. Synthesis and evaluation of anti-tubercular and antibacterial activities of new 4-(2,6-dichlorobenzyloxy)phenyl thiazole, oxazole and imidazole derivatives. Part 2. European Journal of Medicinal Chemistry. 49: 164-71. PMID 22264895 DOI: 10.1016/J.Ejmech.2012.01.007 |
0.442 |
|
| 2012 |
Blaser A, Palmer BD, Sutherland HS, Kmentova I, Franzblau SG, Wan B, Wang Y, Ma Z, Thompson AM, Denny WA. Structure-activity relationships for amide-, carbamate-, and urea-linked analogues of the tuberculosis drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824). Journal of Medicinal Chemistry. 55: 312-26. PMID 22148391 DOI: 10.1021/Jm2012276 |
0.42 |
|
| 2012 |
Lawal TO, Adeniyi BA, Adegoke AO, Franzblau SG, Mahady GB. In vitro susceptibility of Mycobacterium tuberculosis to extracts of Eucalyptus camaldulensis and Eucalyptus torelliana and isolated compounds. Pharmaceutical Biology. 50: 92-8. PMID 22129202 DOI: 10.3109/13880209.2011.625953 |
0.442 |
|
| 2012 |
Chopra S, Matsuyama K, Tran T, Malerich JP, Wan B, Franzblau SG, Lun S, Guo H, Maiga MC, Bishai WR, Madrid PB. Evaluation of gyrase B as a drug target in Mycobacterium tuberculosis Journal of Antimicrobial Chemotherapy. 67: 415-421. PMID 22052686 DOI: 10.1093/Jac/Dkr449 |
0.406 |
|
| 2012 |
Gao W, Napolitano J, Kim J, Lee I, Lee J, Choi J, Rodríguez-Brasco M, Jaki B, Cho S, McAlpine J, Pauli G, Kim J, Suh J, Franzblau S. New insights on the structure of the anti-TB peptide H14: Crystal structure, 1H NMR full spin analysis, and biosynthetic pathway Planta Medica. 78. DOI: 10.1055/S-0032-1321294 |
0.308 |
|
| 2012 |
Hwang C, Jaki B, Klein L, Lankin D, McAlpine J, Napolitano J, Franzblau S, Cho S, Stamets P, Pauli G. Biological and chemical evaluation of anti-TB coumarins from the polypore mushroom, Fomitopsis officinalis Planta Medica. 78. DOI: 10.1055/S-0032-1321157 |
0.61 |
|
| 2012 |
Wei X, Tanouye U, Carlson S, Hwang C, Kim M, Cho S, Franzblau S, Murphy B. Evaluation of anti-tuberculosis secondary metabolites from Deep Lake Michigan sediment strain Micromonospora tulbaghiae Planta Medica. 78. DOI: 10.1055/S-0032-1320778 |
0.578 |
|
| 2012 |
Hwang C, Jaki B, Napolitano J, Lankin D, McAlpine J, Franzblau S, Cho S, Pearce C, Pauli G. Biological and chemical assessment of vermitrasporin, an anti-TB active metabolite from the fungus MSX 105528 Planta Medica. 78. DOI: 10.1055/S-0032-1320777 |
0.624 |
|
| 2012 |
Cai G, Napolitano J, McAlpine J, Cho S, Wang Y, Jaki B, Suh J, Yang S, Lee I, Pauli G, Franzblau S. Isolation of novel anti-TB cyclohexapeptides from actinomycetes Planta Medica. 78. DOI: 10.1055/S-0032-1320753 |
0.427 |
|
| 2012 |
Panlilio BG, MacAbeo APG, Knorn M, Kohls P, Richomme P, Kouam SF, Gehle D, Krohn K, Franzblau SG, Zhang Q, Aguinaldo MAM. A lanostane aldehyde from Momordica charantia Phytochemistry Letters. 5: 682-684. DOI: 10.1016/J.Phytol.2012.07.006 |
0.417 |
|
| 2012 |
Murali K, Avinash R, Kirthiga R, Franzblau SG. Synthesis, antibacterial, and antitubercular studies of some novel isatin derivatives Medicinal Chemistry Research. 1-6. DOI: 10.1007/S00044-012-9971-7 |
0.416 |
|
| 2012 |
Vergelli C, Cilibrizzi A, Crocetti L, Graziano A, Dal Piaz V, Wan B, Wang Y, Franzblau S, Giovannoni MP. Synthesis and Evaluation as Antitubercular Agents of 5-Arylethenyl and 5-(Hetero)aryl-3-Isoxazolecarboxylate Drug Development Research. 74: 162-172. DOI: 10.1002/Ddr.21057 |
0.45 |
|
| 2011 |
Jin Y, Gill SK, Kirchhoff PD, Wan B, Franzblau SG, Garcia GA, Showalter HD. Synthesis and structure-activity relationships of novel substituted 8-amino, 8-thio, and 1,8-pyrazole congeners of antitubercular rifamycin S and rifampin. Bioorganic & Medicinal Chemistry Letters. 21: 6094-9. PMID 21903392 DOI: 10.1016/J.Bmcl.2011.08.054 |
0.416 |
|
| 2011 |
Pavan FR, Poelhsitz GV, Barbosa MI, Leite SR, Batista AA, Ellena J, Sato LS, Franzblau SG, Moreno V, Gambino D, Leite CQ. Ruthenium(II) phosphine/diimine/picolinate complexes: inorganic compounds as agents against tuberculosis. European Journal of Medicinal Chemistry. 46: 5099-107. PMID 21875763 DOI: 10.1016/J.Ejmech.2011.08.023 |
0.407 |
|
| 2011 |
Thompson AM, Sutherland HS, Palmer BD, Kmentova I, Blaser A, Franzblau SG, Wan B, Wang Y, Ma Z, Denny WA. Synthesis and structure-activity relationships of varied ether linker analogues of the antitubercular drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5h-imidazo[2,1-b][1,3]oxazine (PA-824). Journal of Medicinal Chemistry. 54: 6563-85. PMID 21846109 DOI: 10.1021/Jm200377R |
0.395 |
|
| 2011 |
Moraski GC, Markley LD, Hipskind PA, Boshoff H, Cho S, Franzblau SG, Miller MJ. Advent of Imidazo[1,2-a]pyridine-3-carboxamides with Potent Multi- and Extended Drug Resistant Antituberculosis Activity. Acs Medicinal Chemistry Letters. 2: 466-470. PMID 21691438 DOI: 10.1021/Ml200036R |
0.477 |
|
| 2011 |
Lu X, Wan B, Franzblau SG, You Q. Design, synthesis and anti-tubercular evaluation of new 2-acylated and 2-alkylated amino-5-(4-(benzyloxy)phenyl)thiophene-3-carboxylic acid derivatives. Part 1. European Journal of Medicinal Chemistry. 46: 3551-63. PMID 21641695 DOI: 10.1016/J.Ejmech.2011.05.018 |
0.493 |
|
| 2011 |
Gutka HJ, Franzblau SG, Movahedzadeh F, Abad-Zapatero C. Crystallization and preliminary X-ray characterization of the glpX-encoded class II fructose-1,6-bisphosphatase from Mycobacterium tuberculosis. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 710-3. PMID 21636919 DOI: 10.1107/S1744309111014722 |
0.764 |
|
| 2011 |
Khoje AD, Charnock C, Wan B, Franzblau S, Gundersen L. Synthesis and antimycobacterial activities of non-purine analogs of 6-aryl-9-benzylpurines: Imidazopyridines, pyrrolopyridines, benzimidazoles, and indoles. Bioorganic & Medicinal Chemistry. 19: 3483-3491. PMID 21546254 DOI: 10.1016/J.Bmc.2011.04.023 |
0.389 |
|
| 2011 |
MacAbeo APG, Vidar WS, Chen X, Decker M, Heilmann J, Wan B, Franzblau SG, Galvez EV, Aguinaldo MAM, Cordell GA. Mycobacterium tuberculosis and cholinesterase inhibitors from Voacanga globosa European Journal of Medicinal Chemistry. 46: 3118-3123. PMID 21546135 DOI: 10.1016/J.Ejmech.2011.04.025 |
0.484 |
|
| 2011 |
Truong NB, Pham CV, Doan HT, Nguyen HV, Nguyen CM, Nguyen HT, Zhang HJ, Fong HH, Franzblau SG, Soejarto DD, Chau MV. Antituberculosis cycloartane triterpenoids from Radermachera boniana. Journal of Natural Products. 74: 1318-22. PMID 21469696 DOI: 10.1021/Np200022B |
0.311 |
|
| 2011 |
Lu JP, Yuan XH, Yuan H, Wang WL, Wan B, Franzblau SG, Ye QZ. Inhibition of Mycobacterium tuberculosis methionine aminopeptidases by bengamide derivatives. Chemmedchem. 6: 1041-8. PMID 21465667 DOI: 10.1002/Cmdc.201100003 |
0.395 |
|
| 2011 |
Gutka HJ, Rukseree K, Wheeler PR, Franzblau SG, Movahedzadeh F. glpX gene of Mycobacterium tuberculosis: heterologous expression, purification, and enzymatic characterization of the encoded fructose 1,6-bisphosphatase II. Applied Biochemistry and Biotechnology. 164: 1376-89. PMID 21451980 DOI: 10.1007/S12010-011-9219-X |
0.776 |
|
| 2011 |
Singh K, Singh K, Wan B, Franzblau S, Chibale K, Balzarini J. Facile transformation of Biginelli pyrimidin-2(1H)-ones to pyrimidines. In vitro evaluation as inhibitors of Mycobacterium tuberculosis and modulators of cytostatic activity. European Journal of Medicinal Chemistry. 46: 2290-4. PMID 21450375 DOI: 10.1016/J.Ejmech.2011.03.010 |
0.484 |
|
| 2011 |
Bungihan ME, Tan MA, Kitajima M, Kogure N, Franzblau SG, Dela Cruz TEE, Takayama H, Nonato MG. Bioactive metabolites of Diaporthe sp. P133, an endophytic fungus isolated from Pandanus amaryllifolius Journal of Natural Medicines. 65: 606-609. PMID 21394664 DOI: 10.1007/S11418-011-0518-X |
0.354 |
|
| 2011 |
Hans RH, Wiid IJ, van Helden PD, Wan B, Franzblau SG, Gut J, Rosenthal PJ, Chibale K. Novel thiolactone-isatin hybrids as potential antimalarial and antitubercular agents. Bioorganic & Medicinal Chemistry Letters. 21: 2055-8. PMID 21376591 DOI: 10.1016/J.Bmcl.2011.02.008 |
0.454 |
|
| 2011 |
Higuchi CT, Sannomiya M, Pavan FR, Leite SR, Sato DN, Franzblau SG, Sacramento LV, Vilegas W, Leite CQ. Byrsonima fagifolia Niedenzu Apolar Compounds with Antitubercular Activity. Evidence-Based Complementary and Alternative Medicine : Ecam. 2011: 128349. PMID 19091782 DOI: 10.1093/Ecam/Nen077 |
0.366 |
|
| 2011 |
Lawal TO, Adeniyi B, Wan AB, Franzblau SG, Mahady GB. In-vitro susceptibility of mycobacterium tuberculosis to extracts of uvaria afzelli Scott Elliot and Tetracera Alnifolia willd African Journal of Biomedical Research. 14: 17-21. DOI: 10.4314/Ajbr.V14I1 |
0.473 |
|
| 2011 |
Gutka HJ, Franzblau SG, Movahedzadeh F, Abad-Zapatero C. Structural characterization of the fructose 1,6-bisphosphatase (II) fromM. tuberculosis Acta Crystallographica Section a Foundations of Crystallography. 67: C477-C477. DOI: 10.1107/S0108767311087939 |
0.781 |
|
| 2011 |
Truong BN, Pham VC, Mai HDT, Nguyen VH, Nguyen MC, Nguyen TH, Zhang HJ, Fong HHS, Franzblau SG, Soejarto DD, Chau VM. Chemical constituents from Xylosma longifolia and their anti-tubercular activity Phytochemistry Letters. 4: 250-253. DOI: 10.1016/J.Phytol.2011.04.008 |
0.386 |
|
| 2011 |
Khanye SD, Wan B, Franzblau SG, Gut J, Rosenthal PJ, Smith GS, Chibale K. Synthesis and in vitro antimalarial and antitubercular activity of gold(III) complexes containing thiosemicarbazone ligands Journal of Organometallic Chemistry. 696: 3392-3396. DOI: 10.1016/J.Jorganchem.2011.07.026 |
0.373 |
|
| 2010 |
Moraski GC, Franzblau SG, Miller MJ. UTILIZTION OF THE SUZUKI COUPLING TO ENHANCE THE ANTITUBERCULOSIS ACTIVITY OF ARYL OXAZOLES. Heterocycles. 80: 977-988. PMID 22003265 DOI: 10.3987/Com-09-S(S)69 |
0.382 |
|
| 2010 |
Villaflores OB, Macabeo AP, Gehle D, Krohn K, Franzblau SG, Aguinaldo AM. Phytoconstituents from Alpinia purpurata and their in vitro inhibitory activity against Mycobacterium tuberculosis. Pharmacognosy Magazine. 6: 339-44. PMID 21120040 DOI: 10.4103/0973-1296.71785 |
0.398 |
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| 2010 |
Chen L, Zhou B, Zhang S, Wu L, Wang Y, Franzblau SG, Zhang ZY. Identification and characterization of novel inhibitors of mPTPB, an essential virulent phosphatase from Mycobacterium tuberculosis. Acs Medicinal Chemistry Letters. 1: 355-359. PMID 21116447 DOI: 10.1021/Ml1001135 |
0.45 |
|
| 2010 |
Mo S, Krunic A, Santarsiero BD, Franzblau SG, Orjala J. Hapalindole-related alkaloids from the cultured cyanobacterium Fischerella ambigua. Phytochemistry. 71: 2116-23. PMID 20965528 DOI: 10.1016/J.Phytochem.2010.09.004 |
0.351 |
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| 2010 |
Raman N, Jeyamurugan R, Senthilkumar R, Rajkapoor B, Franzblau SG. In vivo and in vitro evaluation of highly specific thiolate carrier group copper(II) and zinc(II) complexes on Ehrlich ascites carcinoma tumor model. European Journal of Medicinal Chemistry. 45: 5438-51. PMID 20864225 DOI: 10.1016/J.Ejmech.2010.09.004 |
0.325 |
|
| 2010 |
Khoje AD, Kulendrn A, Charnock C, Wan B, Franzblau S, Gundersen LL. Synthesis of non-purine analogs of 6-aryl-9-benzylpurines, and their antimycobacterial activities. Compounds modified in the imidazole ring. Bioorganic & Medicinal Chemistry. 18: 7274-82. PMID 20833056 DOI: 10.1016/J.Bmc.2010.08.016 |
0.486 |
|
| 2010 |
Sturdy M, Krunic A, Cho S, Franzblau S, Orjala J. Eucapsitrione, an anti-Mycobacterium tuberculosis anthraquinone derivative from the cultured freshwater cyanobacterium Eucapsis sp. Journal of Natural Products. 73: 1441-3. PMID 20795743 DOI: 10.1021/Np100299V |
0.437 |
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| 2010 |
Pieroni M, Lilienkampf A, Wang Y, Wan B, Cho S, Franzblau SG, Kozikowski AP. NOC chemistry for tuberculosis - Further investigations on the structure-activity relationships of antitubercular isoxazole-3-carboxylic acid ester derivatives Chemmedchem. 5: 1667-1672. PMID 20718072 DOI: 10.1002/Cmdc.201000169 |
0.406 |
|
| 2010 |
Aponte JC, Vaisberg AJ, Castillo D, Gonzalez G, Estevez Y, Arevalo J, Quiliano M, Zimic M, Verástegui M, Málaga E, Gilman RH, Bustamante JM, Tarleton RL, Wang Y, Franzblau SG, et al. Trypanoside, anti-tuberculosis, leishmanicidal, and cytotoxic activities of tetrahydrobenzothienopyrimidines. Bioorganic & Medicinal Chemistry. 18: 2880-6. PMID 20356752 DOI: 10.1016/J.Bmc.2010.03.018 |
0.448 |
|
| 2010 |
Scher JM, Schinkovitz A, Zapp J, Wang Y, Franzblau SG, Becker H, Lankin DC, Pauli GF. Structure and anti-TB activity of trachylobanes from the liverwort Jungermannia exsertifolia ssp. cordifolia. Journal of Natural Products. 73: 656-63. PMID 20353194 DOI: 10.1021/Np900806J |
0.447 |
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| 2010 |
Na M, Ding Y, Wang B, Tekwani BL, Schinazi RF, Franzblau S, Kelly M, Stone R, Li XC, Ferreira D, Hamann MT. Anti-infective discorhabdins from a deep-water alaskan sponge of the genus Latrunculia. Journal of Natural Products. 73: 383-7. PMID 20337497 DOI: 10.1021/Np900281R |
0.372 |
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| 2010 |
Hong Q, Minter DE, Franzblau SG, Arfan M, Amin H, Reinecke MG. Anti-tuberculosis compounds from Mallotus philippinensis. Natural Product Communications. 5: 211-7. PMID 20334129 DOI: 10.1177/1934578X1000500208 |
0.41 |
|
| 2010 |
Inui T, Wang Y, Nikolic D, Smith DC, Franzblau SG, Pauli GF. Sesquiterpenes from Oplopanax horridus. Journal of Natural Products. 73: 563-7. PMID 20218656 DOI: 10.1021/Np900674D |
0.376 |
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| 2010 |
Fang M, Toogood RD, Macova A, Ho K, Franzblau SG, McNeil MR, Sanders DA, Palmer DR. Succinylphosphonate esters are competitive inhibitors of MenD that show active-site discrimination between homologous alpha-ketoglutarate-decarboxylating enzymes. Biochemistry. 49: 2672-9. PMID 20199062 DOI: 10.1021/Bi901432D |
0.368 |
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| 2010 |
Zhou B, He Y, Zhang X, Xu J, Luo Y, Wang Y, Franzblau SG, Yang Z, Chan RJ, Liu Y, Zheng J, Zhang ZY. Targeting mycobacterium protein tyrosine phosphatase B for antituberculosis agents. Proceedings of the National Academy of Sciences of the United States of America. 107: 4573-8. PMID 20167798 DOI: 10.1073/Pnas.0909133107 |
0.343 |
|
| 2010 |
Pavan FR, da S Maia PI, Leite SR, Deflon VM, Batista AA, Sato DN, Franzblau SG, Leite CQ. Thiosemicarbazones, semicarbazones, dithiocarbazates and hydrazide/hydrazones: anti-Mycobacterium tuberculosis activity and cytotoxicity. European Journal of Medicinal Chemistry. 45: 1898-905. PMID 20163897 DOI: 10.1016/J.Ejmech.2010.01.028 |
0.472 |
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| 2010 |
Lin AS, Stout EP, Prudhomme J, Le Roch K, Fairchild CR, Franzblau SG, Aalbersberg W, Hay ME, Kubanek J. Bioactive bromophycolides R-U from the Fijian red alga Callophycus serratus. Journal of Natural Products. 73: 275-8. PMID 20141173 DOI: 10.1021/Np900686W |
0.311 |
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| 2010 |
Moraski GC, Chang M, Villegas-Estrada A, Franzblau SG, Möllmann U, Miller MJ. Structure-activity relationship of new anti-tuberculosis agents derived from oxazoline and oxazole benzyl esters. European Journal of Medicinal Chemistry. 45: 1703-16. PMID 20116900 DOI: 10.1016/J.Ejmech.2009.12.074 |
0.489 |
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| 2010 |
Maroz A, Shinde SS, Franzblau SG, Ma Z, Denny WA, Palmer BD, Anderson RF. Release of nitrite from the antitubercular nitroimidazole drug PA-824 and analogues upon one-electron reduction in protic, non-aqueous solvent. Organic & Biomolecular Chemistry. 8: 413-8. PMID 20066278 DOI: 10.1039/B915877D |
0.396 |
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| 2010 |
Hans RH, Guantai EM, Lategan C, Smith PJ, Wan B, Franzblau SG, Gut J, Rosenthal PJ, Chibale K. Synthesis, antimalarial and antitubercular activity of acetylenic chalcones. Bioorganic & Medicinal Chemistry Letters. 20: 942-4. PMID 20045640 DOI: 10.1016/J.Bmcl.2009.12.062 |
0.48 |
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| 2010 |
Mao J, Yuan H, Wang Y, Wan B, Pak D, He R, Franzblau SG. Synthesis and antituberculosis activity of novel mefloquine-isoxazole carboxylic esters as prodrugs. Bioorganic & Medicinal Chemistry Letters. 20: 1263-8. PMID 20022500 DOI: 10.1016/J.Bmcl.2009.11.105 |
0.496 |
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| 2010 |
Lilienkampf A, Pieroni M, Wan B, Wang Y, Franzblau SG, Kozikowski AP. Rational design of 5-phenyl-3-isoxazolecarboxylic acid ethyl esters as growth inhibitors of Mycobacterium tuberculosis. A potent and selective series for further drug development Journal of Medicinal Chemistry. 53: 678-688. PMID 20000577 DOI: 10.1021/Jm901273N |
0.515 |
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| 2010 |
Guo S, Song Y, Huang Q, Yuan H, Wan B, Wang Y, He R, Beconi MG, Franzblau SG, Kozikowski AP. Identification, synthesis, and pharmacological evaluation of tetrahydroindazole based ligands as novel antituberculosis agents Journal of Medicinal Chemistry. 53: 649-659. PMID 20000470 DOI: 10.1021/Jm901235P |
0.502 |
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| 2010 |
Sutherland HS, Blaser A, Kmentova I, Franzblau SG, Wan B, Wang Y, Ma Z, Palmer BD, Denny WA, Thompson AM. Synthesis and structure-activity relationships of antitubercular 2-nitroimidazooxazines bearing heterocyclic side chains. Journal of Medicinal Chemistry. 53: 855-66. PMID 19968290 DOI: 10.1021/Jm901378U |
0.426 |
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| 2010 |
Pavan FR, Poelhsitz GV, do Nascimento FB, Leite SR, Batista AA, Deflon VM, Sato DN, Franzblau SG, Leite CQ. Ruthenium (II) phosphine/picolinate complexes as antimycobacterial agents. European Journal of Medicinal Chemistry. 45: 598-601. PMID 19931948 DOI: 10.1016/J.Ejmech.2009.10.049 |
0.383 |
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| 2010 |
Palmer BD, Thompson AM, Sutherland HS, Blaser A, Kmentova I, Franzblau SG, Wan B, Wang Y, Ma Z, Denny WA. Synthesis and structure-activity studies of biphenyl analogues of the tuberculosis drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824). Journal of Medicinal Chemistry. 53: 282-94. PMID 19928920 DOI: 10.1021/Jm901207N |
0.444 |
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| 2010 |
Gordien AY, Gray AI, Ingleby K, Franzblau SG, Seidel V. Activity of Scottish plant, lichen and fungal endophyte extracts against Mycobacterium aurum and Mycobacterium tuberculosis Phytotherapy Research. 24: 692-698. PMID 19827032 DOI: 10.1002/Ptr.2988 |
0.421 |
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| 2009 |
Elkington BG, Southavong B, Sydara K, Souliya O, Vanthanouvong M, Nettavong K, Thammachack B, Pak DH, Riley MC, Franzblau SG, Soejarto DD. Biological evaluation of plants of Laos used in the treatment of tuberculosis in Lao traditional medicine. Pharmaceutical Biology. 47: 26-33. PMID 21479105 DOI: 10.1080/13880200802398002 |
0.352 |
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| 2009 |
Mo S, Krunic A, Pegan SD, Franzblau SG, Orjala J. An antimicrobial guanidine-bearing sesterterpene from the cultured cyanobacterium Scytonema sp. Journal of Natural Products. 72: 2043-5. PMID 19888742 DOI: 10.1021/Np900288X |
0.374 |
|
| 2009 |
Mao J, Yuan H, Wang Y, Wan B, Pieroni M, Huang Q, Van Breemen RB, Kozikowski AP, Franzblau SG. From serendipity to rational antituberculosis drug discovery of mefloquine-isoxazole carboxylic acid esters Journal of Medicinal Chemistry. 52: 6966-6978. PMID 19863050 DOI: 10.1021/Jm900340A |
0.423 |
|
| 2009 |
Huang Q, Mao J, Wan B, Wang Y, Brun R, Franzblau SG, Kozikowski AP. Searching for new cures for tuberculosis: Design, synthesis, and biological evaluation of 2-methylbenzothiazoles Journal of Medicinal Chemistry. 52: 6757-6767. PMID 19817445 DOI: 10.1021/Jm901112F |
0.516 |
|
| 2009 |
Guo S, Tipparaju SK, Pegan SD, Wan B, Mo S, Orjala J, Mesecar AD, Franzblau SG, Kozikowski AP. Natural product leads for drug discovery: isolation, synthesis and biological evaluation of 6-cyano-5-methoxyindolo[2,3-a]carbazole based ligands as antibacterial agents. Bioorganic & Medicinal Chemistry. 17: 7126-30. PMID 19783449 DOI: 10.1016/J.Bmc.2009.08.061 |
0.459 |
|
| 2009 |
Pieroni M, Lilienkampf A, Baojie W, Yuehong W, Franzblau SG, Kozikowski AP. Synthesis, biological evaluation, and structure-activity relationships for 5-[(E)-2-arylethenyl]-3-isoxazolecarboxylic acid alkyl ester derivatives as valuable antitubercular chemotypes Journal of Medicinal Chemistry. 52: 6287-6296. PMID 19757815 DOI: 10.1021/Jm900513A |
0.48 |
|
| 2009 |
Gordien AY, Gray AI, Franzblau SG, Seidel V. Antimycobacterial terpenoids from Juniperus communis L. (Cuppressaceae) Journal of Ethnopharmacology. 126: 500-505. PMID 19755141 DOI: 10.1016/J.Jep.2009.09.007 |
0.512 |
|
| 2009 |
Zhao Y, Bacher A, Illarionov B, Fischer M, Georg G, Ye QZ, Fanwick PE, Franzblau SG, Wan B, Cushman M. Discovery and development of the covalent hydrates of trifluoromethylated pyrazoles as riboflavin synthase inhibitors with antibiotic activity against Mycobacterium tuberculosis Journal of Organic Chemistry. 74: 5297-5303. PMID 19545132 DOI: 10.1021/Jo900768C |
0.472 |
|
| 2009 |
Lilienkampf A, Jialin M, Baojie W, Yuehong W, Franzblau SG, Kozikowski AP. Structure-Activity relationships for a series of quinoline-based compounds active against replicating and nonreplicating mycobacterium tuberculosis Journal of Medicinal Chemistry. 52: 2109-2118. PMID 19271749 DOI: 10.1021/Jm900003C |
0.507 |
|
| 2009 |
Pegan SD, Rukseree K, Franzblau SG, Mesecar AD. Structural basis for catalysis of a tetrameric class IIa fructose 1,6-bisphosphate aldolase from Mycobacterium tuberculosis. Journal of Molecular Biology. 386: 1038-53. PMID 19167403 DOI: 10.1016/J.Jmb.2009.01.003 |
0.424 |
|
| 2009 |
Miller MJ, Zhu H, Xu Y, Wu C, Walz AJ, Vergne A, Roosenberg JM, Moraski G, Minnick AA, McKee-Dolence J, Hu J, Fennell K, Kurt Dolence E, Dong L, Franzblau S, et al. Utilization of microbial iron assimilation processes for the development of new antibiotics and inspiration for the design of new anticancer agents. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 22: 61-75. PMID 19130268 DOI: 10.1007/S10534-008-9185-0 |
0.301 |
|
| 2009 |
Figueiredo R, Moiteiro C, Medeiros MA, da Silva PA, Ramos D, Spies F, Ribeiro MO, Lourenço MC, Júnior IN, Gaspar MM, Cruz ME, Curto MJ, Franzblau SG, Orozco H, Aguilar D, et al. Synthesis and evaluation of rifabutin analogs against Mycobacterium avium and H(37)Rv, MDR and NRP Mycobacterium tuberculosis. Bioorganic & Medicinal Chemistry. 17: 503-11. PMID 19119013 DOI: 10.1016/J.Bmc.2008.12.006 |
0.451 |
|
| 2009 |
Thompson AM, Blaser A, Anderson RF, Shinde SS, Franzblau SG, Ma Z, Denny WA, Palmer BD. Synthesis, reduction potentials, and antitubercular activity of ring A/B analogues of the bioreductive drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824). Journal of Medicinal Chemistry. 52: 637-45. PMID 19099398 DOI: 10.1021/Jm801087E |
0.367 |
|
| 2008 |
Wei X, Rodríguez AD, Wang Y, Franzblau SG. Synthesis and in vitro biological evaluation of ring B abeo-sterols as novel inhibitors of Mycobacterium tuberculosis. Bioorganic & Medicinal Chemistry Letters. 18: 5448-50. PMID 18818073 DOI: 10.1016/J.Bmcl.2008.09.029 |
0.431 |
|
| 2008 |
Jaki BU, Franzblau SG, Chadwick LR, Lankin DC, Zhang F, Wang Y, Pauli GF. Purity-activity relationships of natural products: the case of anti-TB active ursolic acid. Journal of Natural Products. 71: 1742-8. PMID 18798682 DOI: 10.1021/Np800329J |
0.442 |
|
| 2008 |
Mao J, Eoh H, He R, Wang Y, Wan B, Franzblau SG, Crick DC, Kozikowski AP. Structure-activity relationships of compounds targeting mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate synthase. Bioorganic & Medicinal Chemistry Letters. 18: 5320-3. PMID 18783951 DOI: 10.1016/J.Bmcl.2008.08.034 |
0.457 |
|
| 2008 |
Yuan H, He R, Wan B, Wang Y, Pauli GF, Franzblau SG, Kozikowski AP. Modification of the side chain of micromolide, an anti-tuberculosis natural product Bioorganic and Medicinal Chemistry Letters. 18: 5311-5315. PMID 18774716 DOI: 10.1016/J.Bmcl.2008.08.027 |
0.404 |
|
| 2008 |
Zhu ZJ, Krasnykh O, Pan D, Petukhova V, Yu G, Liu Y, Liu H, Hong S, Wang Y, Wan B, Liang W, Franzblau SG. Structure-activity relationships of macrolides against Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland). 88: S49-63. PMID 18762153 DOI: 10.1016/S1472-9792(08)70036-2 |
0.491 |
|
| 2008 |
Hurdle JG, Lee RB, Budha NR, Carson EI, Qi J, Scherman MS, Cho SH, McNeil MR, Lenaerts AJ, Franzblau SG, Meibohm B, Lee RE. A microbiological assessment of novel nitrofuranylamides as anti-tuberculosis agents. The Journal of Antimicrobial Chemotherapy. 62: 1037-45. PMID 18693235 DOI: 10.1093/Jac/Dkn307 |
0.472 |
|
| 2008 |
Vicente E, Villar R, Burguete A, Solano B, Pérez-Silanes S, Aldana I, Maddry JA, Lenaerts AJ, Franzblau SG, Cho SH, Monge A, Goldman RC. Efficacy of quinoxaline-2-carboxylate 1,4-di-N-oxide derivatives in experimental tuberculosis. Antimicrobial Agents and Chemotherapy. 52: 3321-6. PMID 18625764 DOI: 10.1128/Aac.00379-08 |
0.449 |
|
| 2008 |
Deng S, Wang Y, Inui T, Chen SN, Farnsworth NR, Cho S, Franzblau SG, Pauli GF. Anti-TB polyynes from the roots of Angelica sinensis. Phytotherapy Research : Ptr. 22: 878-82. PMID 18567055 DOI: 10.1002/Ptr.2303 |
0.511 |
|
| 2008 |
Zhou Y, Beeler AB, Cho S, Wang Y, Franzblau SG, Snyder JK. Library synthesis using 5,6,7,8-tetrahydro-1,6-naphthyridines as scaffolds. Journal of Combinatorial Chemistry. 10: 534-40. PMID 18517255 DOI: 10.1021/Cc800038R |
0.33 |
|
| 2008 |
Villar R, Vicente E, Solano B, Pérez-Silanes S, Aldana I, Maddry JA, Lenaerts AJ, Franzblau SG, Cho SH, Monge A, Goldman RC. In vitro and in vivo antimycobacterial activities of ketone and amide derivatives of quinoxaline 1,4-di-N-oxide. The Journal of Antimicrobial Chemotherapy. 62: 547-54. PMID 18502817 DOI: 10.1093/Jac/Dkn214 |
0.471 |
|
| 2008 |
Karioti A, Skaltsa H, Zhang X, Tonge PJ, Perozzo R, Kaiser M, Franzblau SG, Tasdemir D. Inhibiting enoyl-ACP reductase (FabI) across pathogenic microorganisms by linear sesquiterpene lactones from Anthemis auriculata. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 15: 1125-9. PMID 18424102 DOI: 10.1016/J.Phymed.2008.02.018 |
0.408 |
|
| 2008 |
Tan MA, Takayama H, Aimi N, Kitajima M, Franzblau SG, Nonato MG. Antitubercular triterpenes and phytosterols from Pandanus tectorius Soland. var. laevis Journal of Natural Medicines. 62: 232-235. PMID 18404330 DOI: 10.1007/S11418-007-0218-8 |
0.35 |
|
| 2008 |
Velaparthi S, Brunsteiner M, Uddin R, Wan B, Franzblau SG, Petukhov PA. 5-tert-butyl-N-pyrazol-4-yl-4,5,6,7-tetrahydrobenzo[d]isoxazole-3-carboxamide derivatives as novel potent inhibitors of Mycobacterium tuberculosis pantothenate synthetase: initiating a quest for new antitubercular drugs. Journal of Medicinal Chemistry. 51: 1999-2002. PMID 18335974 DOI: 10.1021/Jm701372R |
0.459 |
|
| 2008 |
Sayed KA, Khalil AA, Yousaf M, Labadie G, Kumar GM, Franzblau SG, Mayer AM, Avery MA, Hamann MT. Semisynthetic studies on the manzamine alkaloids. Journal of Natural Products. 71: 300-8. PMID 18198837 DOI: 10.1021/Np0703702 |
0.39 |
|
| 2008 |
Tasdemir D, Brun R, Franzblau SG, Sezgin Y, Çalis I. Evaluation of antiprotozoal and antimycobacterial activities of the resin glycosides and the other metabolites of Scrophularia cryptophila Phytomedicine. 15: 209-215. PMID 17761408 DOI: 10.1016/J.Phymed.2007.07.032 |
0.42 |
|
| 2008 |
Hong Q, Minter DE, Franzblau SG, Reinecke MG. Anti-tuberculosis Compounds from two Bolivian Medicinal Plants, Senecio Mathewsii and Usnea Florida Natural Product Communications. 3: 1934578X0800300. DOI: 10.1177/1934578X0800300901 |
0.403 |
|
| 2008 |
Choi TA, Czerwonka R, Forke R, Jäger A, Knöll J, Krahl MP, Krause T, Reddy KR, Franzblau SG, Knölker HJ. Transition metals in organic synthesis - Part 83#: Synthesis and pharmacological potential of carbazoles Medicinal Chemistry Research. 17: 374-385. DOI: 10.1007/S00044-007-9073-0 |
0.782 |
|
| 2008 |
Choi TA, Czerwonka R, Forke R, Jaeger A, Knoell J, Krahl MP, Krause T, Reddy KR, Franzblau SG, Knoelker H. ChemInform Abstract: Transition Metals in Organic Synthesis. Part 83. Synthesis and Pharmacological Potential of Carbazoles Cheminform. 39. DOI: 10.1002/CHIN.200849243 |
0.7 |
|
| 2008 |
Hong Q, Minter DE, Franzblau SG, Reinecke MG. Anti-tuberculosis compounds from two Bolivian medicinal plants, Senecio mathewsii and Usnea florida Natural Product Communications. 3: 1337-1384. |
0.374 |
|
| 2007 |
Lane AL, Stout EP, Hay ME, Prusak AC, Hardcastle K, Fairchild CR, Franzblau SG, Le Roch K, Prudhomme J, Aalbersberg W, Kubanek J. Callophycoic acids and callophycols from the Fijian red alga Callophycus serratus. The Journal of Organic Chemistry. 72: 7343-51. PMID 17715978 DOI: 10.1021/Jo071210Y |
0.344 |
|
| 2007 |
Mao J, Wang Y, Wan B, Kozikowski AP, Franzblau SG. Design, synthesis, and pharmacological evaluation of mefloquine-based ligands as novel antituberculosis agents Chemmedchem. 2: 1624-1630. PMID 17680579 DOI: 10.1002/Cmdc.200700112 |
0.495 |
|
| 2007 |
Aguinaldo AM, Dalangin-Mallari VM, Macabeo APG, Byrne LT, Abe F, Yamauchi T, Franzblau SG. Quinoline alkaloids from Lunasia amara inhibit Mycobacterium tuberculosis H37Rv in vitro International Journal of Antimicrobial Agents. 29: 744-746. PMID 17399957 DOI: 10.1016/J.Ijantimicag.2007.02.004 |
0.455 |
|
| 2007 |
Inui T, Wang Y, Deng S, Smith DC, Franzblau SG, Pauli GF. Counter-current chromatography based analysis of synergy in an anti-tuberculosis ethnobotanical. Journal of Chromatography. A. 1151: 211-5. PMID 17316661 DOI: 10.1016/J.Chroma.2007.01.127 |
0.353 |
|
| 2007 |
Case RJ, Wang Y, Franzblau SG, Soejarto DD, Matainaho L, Piskaut P, Pauli GF. Advanced applications of counter-current chromatography in the isolation of anti-tuberculosis constituents from Dracaena angustifolia. Journal of Chromatography. A. 1151: 169-74. PMID 17296204 DOI: 10.1016/J.Chroma.2007.01.022 |
0.372 |
|
| 2007 |
Cho SH, Warit S, Wan B, Hwang CH, Pauli GF, Franzblau SG. Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy. 51: 1380-5. PMID 17210775 DOI: 10.1128/Aac.00055-06 |
0.637 |
|
| 2007 |
Bate AB, Kalin JH, Fooksman EM, Amorose EL, Price CM, Williams HM, Rodig MJ, Mitchell MO, Cho SH, Wang Y, Franzblau SG. Synthesis and antitubercular activity of quaternized promazine and promethazine derivatives. Bioorganic & Medicinal Chemistry Letters. 17: 1346-8. PMID 17188865 DOI: 10.1016/J.Bmcl.2006.11.091 |
0.465 |
|
| 2007 |
Primm TP, Franzblau SG. Recent advances in methodologies for the discovery of antimycobacterial drugs Current Bioactive Compounds. 3: 201-208. DOI: 10.2174/157340707781695550 |
0.369 |
|
| 2007 |
Schinkovitz A, Scher J, Zapp J, Becker H, Wang Y, Franzblau S, Crandall-Stotler B, Stotler R, Pro S, Pauli G. Evaluation of the anti-TB potential of bryophytes Planta Medica. 73. DOI: 10.1055/S-2007-986948 |
0.389 |
|
| 2007 |
Wei X, Rodríguez AD, Wang Y, Franzblau SG. Novel ring B abeo-sterols as growth inhibitors of Mycobacterium tuberculosis isolated from a Caribbean Sea sponge, Svenzea zeai Tetrahedron Letters. 48: 8851-8854. DOI: 10.1016/J.Tetlet.2007.10.070 |
0.396 |
|
| 2006 |
Miller MJ, Zhao G, Vakulenko S, Franzblau S, Möllmann U. New C-3' hydroxamate-substituted and more lipophilic cyclic hydroxamate cephalosporin derivatives as a potential new generation of selective antimicrobial agents. Organic & Biomolecular Chemistry. 4: 4178-85. PMID 17312974 DOI: 10.1039/B612475E |
0.403 |
|
| 2006 |
Tasdemir D, Brun R, Yardley V, Franzblau SG, Rüedi P. Antituberculotic and antiprotozoal activities of primin, a natural benzoquinone: In vitro and in vivo studies Chemistry and Biodiversity. 3: 1230-1237. PMID 17193236 DOI: 10.1002/Cbdv.200690124 |
0.385 |
|
| 2006 |
Bapela NB, Lall N, Fourie PB, Franzblau SG, Van Rensburg CEJ. Activity of 7-methyljuglone in combination with antituberculous drugs against Mycobacterium tuberculosis Phytomedicine. 13: 630-635. PMID 16987644 DOI: 10.1016/J.Phymed.2006.08.001 |
0.491 |
|
| 2006 |
Zhao G, Miller MJ, Franzblau S, Wan B, Möllmann U. Syntheses and studies of quinolone-cephalosporins as potential anti-tuberculosis agents. Bioorganic & Medicinal Chemistry Letters. 16: 5534-7. PMID 16945530 DOI: 10.1016/J.Bmcl.2006.08.045 |
0.473 |
|
| 2006 |
Carballeira NM, Sanabria D, Cruz C, Parang K, Wan B, Franzblau S. 2,6-hexadecadiynoic acid and 2,6-nonadecadiynoic acid: novel synthesized acetylenic fatty acids as potent antifungal agents. Lipids. 41: 507-11. PMID 16933795 DOI: 10.1007/S11745-006-5124-4 |
0.326 |
|
| 2006 |
Choi TA, Czerwonka R, Fröhner W, Krahl MP, Reddy KR, Franzblau SG, Knölker HJ. Synthesis and activity of carbazole derivatives against Mycobacterium tuberculosis. Chemmedchem. 1: 812-5. PMID 16902934 DOI: 10.1002/Cmdc.200600002 |
0.796 |
|
| 2006 |
Rao KV, Donia MS, Peng J, Garcia-Palomero E, Alonso D, Martinez A, Medina M, Franzblau SG, Tekwani BL, Khan SI, Wahyuono S, Willett KL, Hamann MT. Manzamine B and E and ircinal A related alkaloids from an Indonesian Acanthostrongylophora sponge and their activity against infectious, tropical parasitic, and Alzheimer's diseases. Journal of Natural Products. 69: 1034-40. PMID 16872140 DOI: 10.1021/Np0601399 |
0.363 |
|
| 2006 |
Lee S, Kong DH, Yun SH, Lee KR, Lee KP, Franzblau SG, Lee EY, Chang CL. Evaluation of a modified antimycobacterial susceptibility test using Middlebrook 7H10 agar containing 2,3-diphenyl-5-thienyl-(2)-tetrazolium chloride. Journal of Microbiological Methods. 66: 548-51. PMID 16563534 DOI: 10.1016/J.Mimet.2006.02.004 |
0.371 |
|
| 2006 |
Case RJ, Franzblau SG, Wang Y, Cho SH, Soejarto DD, Pauli GF. Ethnopharmacological evaluation of the informant consensus model on anti-tuberculosis claims among the Manus. Journal of Ethnopharmacology. 106: 82-9. PMID 16423480 DOI: 10.1016/J.Jep.2005.12.005 |
0.323 |
|
| 2006 |
Franzblau S. A potentially new treatment for tuberculosis; will a diarylquinoline work for leprosy? International Journal of Leprosy and Other Mycobacterial Diseases : Official Organ of the International Leprosy Association. 73: 32. PMID 15898838 DOI: 10.1489/1544-581X(2005)73[32:Apntfw]2.0.Co;2 |
0.365 |
|
| 2006 |
Rodríguez II, Rodríguez AD, Wang Y, Franzblau SG. Ileabethoxazole: a novel benzoxazole alkaloid with antimycobacterial activity Tetrahedron Letters. 47: 3229-3232. DOI: 10.1016/J.Tetlet.2006.03.048 |
0.41 |
|
| 2006 |
Marrero J, Ospina CA, Rodríguez AD, Baran P, Zhao H, Franzblau SG, Ortega-Barria E. New diterpenes of the pseudopterane class from two closely related Pseudopterogorgia species: isolation, structural elucidation, and biological evaluation Tetrahedron. 62: 6998-7008. DOI: 10.1016/J.Tet.2006.04.070 |
0.367 |
|
| 2005 |
Lall N, Meyer JJM, Wang Y, Bapela NB, van Rensburg CEJ, Fourie B, Franzblau SG. Characterization of Intracellular Activity of Antitubercular Constituents the Roots of Euclea natalensis. Pharmaceutical Biology. 43: 353-357. PMID 28925832 DOI: 10.1080/13880200590951829 |
0.466 |
|
| 2005 |
Cho SH, Goodlett D, Franzblau S. ICAT-based comparative proteomic analysis of non-replicating persistent Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland). 86: 445-60. PMID 16376151 DOI: 10.1016/J.Tube.2005.10.002 |
0.34 |
|
| 2005 |
Gutierrez-Lugo MT, Wang Y, Franzblau SG, Suarez E, Timmermann BN. Antitubercular sterols from Thalia multiflora Horkel ex Koernicke. Phytotherapy Research : Ptr. 19: 876-80. PMID 16261518 DOI: 10.1002/Ptr.1731 |
0.313 |
|
| 2005 |
Pauli GF, Case RJ, Inui T, Wang Y, Cho S, Fischer NH, Franzblau SG. New perspectives on natural products in TB drug research. Life Sciences. 78: 485-94. PMID 16243360 DOI: 10.1016/J.Lfs.2005.09.004 |
0.398 |
|
| 2005 |
Rivero-Cruz I, Acevedo L, Guerrero JA, Martínez S, Bye R, Pereda-Miranda R, Franzblau S, Timmermann BN, Mata R. Antimycobacterial agents from selected Mexican medicinal plants. The Journal of Pharmacy and Pharmacology. 57: 1117-26. PMID 16105233 DOI: 10.1211/Jpp.57.9.0007 |
0.407 |
|
| 2005 |
Akihisa T, Franzblau SG, Tokuda H, Tagata M, Ukiya M, Matsuzawa T, Metori K, Kimura Y, Suzuki T, Yasukawa K. Antitubercular activity and inhibitory effect on Epstein-Barr virus activation of sterols and polyisoprenepolyols from an edible mushroom, Hypsizigus marmoreus. Biological & Pharmaceutical Bulletin. 28: 1117-9. PMID 15930759 DOI: 10.1248/Bpb.28.1117 |
0.378 |
|
| 2005 |
Falzari K, Zhu Z, Pan D, Liu H, Hongmanee P, Franzblau SG. In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy. 49: 1447-54. PMID 15793125 DOI: 10.1128/Aac.49.4.1447-1454.2005 |
0.493 |
|
| 2005 |
Ma C, Case RJ, Wang Y, Zhang HJ, Tan GT, Van Hung N, Cuong NM, Franzblau SG, Soejarto DD, Fong HH, Pauli GF. Anti-tuberculosis constituents from the stem bark of Micromelum hirsutum. Planta Medica. 71: 261-7. PMID 15770548 DOI: 10.1055/S-2005-837826 |
0.485 |
|
| 2005 |
Akihisa T, Franzblau SG, Ukiya M, Okuda H, Zhang F, Yasukawa K, Suzuki T, Kimura Y. Antitubercular activity of triterpenoids from Asteraceae flowers. Biological & Pharmaceutical Bulletin. 28: 158-60. PMID 15635183 DOI: 10.1248/Bpb.28.158 |
0.427 |
|
| 2005 |
Inui T, Case R, Chou E, Soejarto DD, Fong HHS, Franzblau SG, Smith DC, Pauli GF. CCC in the phytochemical analysis of anti-tuberculosis ethnobotanicals Journal of Liquid Chromatography and Related Technologies. 28: 2017-2028. DOI: 10.1081/Jlc-200063660 |
0.323 |
|
| 2005 |
Giddens AC, Boshoff HIM, Franzblau SG, Barry CE, Copp BR. Antimycobacterial natural products: Synthesis and preliminary biological evaluation of the oxazole-containing alkaloid texaline Tetrahedron Letters. 46: 7355-7357. DOI: 10.1016/J.Tetlet.2005.08.119 |
0.39 |
|
| 2004 |
Gua JQ, Wang Y, Franzblau SG, Montenegro G, Timmermann BN. Constituents of Quinchamalium majus with potential antitubercular activity. Zeitschrift FüR Naturforschung. C, Journal of Biosciences. 59: 797-802. PMID 15666537 DOI: 10.1515/Znc-2004-11-1206 |
0.409 |
|
| 2004 |
Mata R, Morales I, Pérez O, Rivero-Cruz I, Acevedo L, Enriquez-Mendoza I, Bye R, Franzblau S, Timmermann B. Antimycobacterial compounds from Piper sanctum. Journal of Natural Products. 67: 1961-8. PMID 15620234 DOI: 10.1021/Np0401260 |
0.364 |
|
| 2004 |
Carballeira NM, Cruz H, Kwong CD, Wan B, Franzblau S. 2-methoxylated fatty acids in marine sponges: defense mechanism against mycobacteria? Lipids. 39: 675-80. PMID 15588025 DOI: 10.1007/S11745-004-1281-8 |
0.377 |
|
| 2004 |
Tangallapally RP, Yendapally R, Lee RE, Hevener K, Jones VC, Lenaerts AJM, McNeil MR, Wang Y, Franzblau S. Synthesis and evaluation of nitrofuranylamides as novel antituberculosis agents Journal of Medicinal Chemistry. 47: 5276-5283. PMID 15456272 DOI: 10.1021/Jm049972Y |
0.501 |
|
| 2004 |
Gu JQ, Wang Y, Franzblau SG, Montenegro G, Timmermann BN. Constituents of Senecio chionophilus with potential antitubercular activity. Journal of Natural Products. 67: 1483-7. PMID 15387646 DOI: 10.1021/Np049831Z |
0.361 |
|
| 2004 |
Jaki B, Franzblau S, Pauli GF. An NMR method towards the routine chiral determination of natural products. Phytochemical Analysis : Pca. 15: 213-9. PMID 15311839 DOI: 10.1002/Pca.760 |
0.302 |
|
| 2004 |
Gu JQ, Wang Y, Franzblau SG, Montenegro G, Yang D, Timmermann BN. Antitubercular constituents of Valeriana laxiflora. Planta Medica. 70: 509-14. PMID 15229801 DOI: 10.1055/S-2004-827149 |
0.38 |
|
| 2004 |
Woldemichael GM, Gutierrez-Lugo MT, Franzblau SG, Wang Y, Suarez E, Timmermann BN. Mycobacterium tuberculosis growth inhibition by constituents of Sapium haematospermum. Journal of Natural Products. 67: 598-603. PMID 15104489 DOI: 10.1021/Np0303411 |
0.393 |
|
| 2003 |
Changsen C, Franzblau SG, Palittapongarnpim P. Improved green fluorescent protein reporter gene-based microplate screening for antituberculosis compounds by utilizing an acetamidase promoter. Antimicrobial Agents and Chemotherapy. 47: 3682-7. PMID 14638465 DOI: 10.1128/Aac.47.12.3682-3687.2003 |
0.332 |
|
| 2003 |
Peng J, Hu JF, Kazi AB, Li Z, Avery M, Peraud O, Hill RT, Franzblau SG, Zhang F, Schinazi RF, Wirtz SS, Tharnish P, Kelly M, Wahyuono S, Hamann MT. Manadomanzamines A and B: a novel alkaloid ring system with potent activity against mycobacteria and HIV-1. Journal of the American Chemical Society. 125: 13382-6. PMID 14583033 DOI: 10.1021/Ja030087Z |
0.352 |
|
| 2003 |
Woldemichael GM, Franzblau SG, Zhang F, Wang Y, Timmermann BN. Inhibitory effect of sterols from Ruprechtia triflora and diterpenes from Calceolaria pinnifolia on the growth of Mycobacterium tuberculosis. Planta Medica. 69: 628-31. PMID 12898418 DOI: 10.1055/S-2003-41109 |
0.328 |
|
| 2003 |
Murillo JI, Encarnación-Dimayuga R, Malmstrøm J, Christophersen C, Franzblau SG. Antimycobacterial flavones from Haplopappus sonorensis Fitoterapia. 74: 226-230. PMID 12727485 DOI: 10.1016/S0367-326X(03)00033-9 |
0.396 |
|
| 2003 |
Luna-Herrera J, Martínez-Cabrera G, Parra-Maldonado R, Enciso-Moreno JA, Torres-López J, Quesada-Pascual F, Delgadillo-Polanco R, Franzblau SG. Use of receiver operating characteristic curves to assess the performance of a microdilution assay for determination of drug susceptibility of clinical isolates of Mycobacterium tuberculosis. European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology. 22: 21-7. PMID 12582740 DOI: 10.1007/S10096-002-0855-5 |
0.365 |
|
| 2002 |
Sandbhor U, Padhye S, Billington D, Rathbone D, Franzblau S, Anson CE, Powell AK. Metal complexes of carboxamidrazone analogs as antitubercular agents. 1. Synthesis, X-ray crystal-structures, spectroscopic properties and antimycobacterial activity against Mycobacterium tuberculosis H(37)Rv. Journal of Inorganic Biochemistry. 90: 127-36. PMID 12031804 DOI: 10.1016/S0162-0134(02)00406-3 |
0.378 |
|
| 2002 |
Peng J, Franzblau SG, Zhang F, Hamann MT. Novel sesquiterpenes and a lactone from the Jamaican sponge Myrmekioderma styx Tetrahedron Letters. 43: 9699-9702. DOI: 10.1016/S0040-4039(02)02369-9 |
0.327 |
|
| 2002 |
Yousaf M, El Sayed KA, Rao KV, Lim CW, Hu JF, Kelly M, Franzblau SG, Zhang F, Peraud O, Hill RT, Hamann MT. 12,34-Oxamanzamines, novel biocatalytic and natural products from manzamine producing Indo-Pacific sponges Tetrahedron. 58: 7397-7402. DOI: 10.1016/S0040-4020(02)00825-6 |
0.4 |
|
| 2001 |
Antoun MD, Ramos Z, Vazques J, Oquendo I, Proctor GR, Gerena L, Franzblau SG. Evaluation of the flora of Puerto Rico for in vitro antiplasmodial and antimycobacterial activities Phytotherapy Research. 15: 638-642. PMID 11746852 DOI: 10.1002/Ptr.880 |
0.378 |
|
| 2001 |
Cantrell CL, Franzblau SG, Fischer NH. Antimycobacterial plant terpenoids. Planta Medica. 67: 685-94. PMID 11731906 DOI: 10.1055/S-2001-18365 |
0.462 |
|
| 2001 |
Wächter GA, Franzblau SG, Montenegro G, Hoffmann JJ, Maiese WM, Timmermann BN. Inhibition of Mycobacterium tuberculosis growth by saringosterol from Lessonia nigrescens Journal of Natural Products. 64: 1463-1464. PMID 11720535 DOI: 10.1021/Np010101Q |
0.435 |
|
| 2001 |
Constantine GH, Karchesy JJ, Franzblau SG, LaFleur LE. (+)-Totarol from Chamaecyparis nootkatensis and activity against Mycobacterium tuberculosis Fitoterapia. 72: 572-574. PMID 11429259 DOI: 10.1016/S0367-326X(01)00272-6 |
0.46 |
|
| 2001 |
Gezginci MH, Martin AR, Franzblau SG. Antimycobacterial activity of substituted isosteres of pyridine- and pyrazinecarboxylic acids. 2. Journal of Medicinal Chemistry. 44: 1560-3. PMID 11334565 DOI: 10.1021/Jm000350W |
0.407 |
|
| 2001 |
Ma Y, Stern RJ, Scherman MS, Vissa VD, Yan W, Jones VC, Zhang F, Franzblau SG, Lewis WH, McNeil MR. Drug targeting Mycobacterium tuberculosis cell wall synthesis: genetics of dTDP-rhamnose synthetic enzymes and development of a microtiter plate-based screen for inhibitors of conversion of dTDP-glucose to dTDP-rhamnose. Antimicrobial Agents and Chemotherapy. 45: 1407-16. PMID 11302803 DOI: 10.1128/Aac.45.5.1407-1416.2001 |
0.447 |
|
| 2001 |
Rugutt JK, Fronczek FR, Franzblau SG, Warner IM. Dihydroparthenolide diol, a novel sesquiterpene lactone Acta Crystallographica Section E Structure Reports Online. 57: o323-o325. DOI: 10.1107/S1600536801004111 |
0.323 |
|
| 2001 |
Murillo-Alvarez JI, Encarnación DR, Franzblau SG. Antimicrobial and cytotoxic activity of some medicinal plants from Baja California Sur (Mexico) Pharmaceutical Biology. 39: 445-449. DOI: 10.1076/Phbi.39.6.445.5877 |
0.386 |
|
| 2000 |
Caldwell CG, Franzblau SG, Suarez E, Timmermann BN. Oleanane triterpenes from Junellia tridens. Journal of Natural Products. 63: 1611-4. PMID 11141098 DOI: 10.1021/Np0002233 |
0.364 |
|
| 2000 |
Mangalindan GC, Talaue MT, Cruz LJ, Franzblau SG, Adams LB, Richardson AD, Ireland CM, Concepcion GP. Agelasine F from a Philippine Agelas sp. sponge exhibits in vitro antituberculosis activity. Planta Medica. 66: 364-5. PMID 10865457 DOI: 10.1055/S-2000-8554 |
0.434 |
|
| 2000 |
König GM, Wright AD, Franzblau SG. Assessment of antimycobacterial activity of a series of mainly marine derived natural products Planta Medica. 66: 337-342. PMID 10865450 DOI: 10.1055/S-2000-8534 |
0.429 |
|
| 2000 |
Acevedo L, Martínez E, Castañeda P, Franzblau S, Timmermann BN, Linares E, Bye R, Mata R. New phenylethanoids from Buddleja cordata subsp. cordata. Planta Medica. 66: 257-61. PMID 10821053 DOI: 10.1055/S-2000-8570 |
0.362 |
|
| 2000 |
Encarnación DR, Franzblau SG, Tapia CA, Cedillo-Rivera R. Screening of marine organisms for antimicrobial and antiprotozoal activity Pharmaceutical Biology. 38: 379-384. DOI: 10.1076/Phbi.38.5.379.5964 |
0.363 |
|
| 1999 |
Wächter GA, Valcic S, Flagg ML, Franzblau SG, Montenegro G, Suarez E, Timmermann BN. Antitubercular activity of pentacyclic triterpenoids from plants of Argentina and Chile. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 6: 341-5. PMID 11962541 DOI: 10.1016/S0944-7113(99)80056-7 |
0.34 |
|
| 1999 |
Cantrell CL, Rajab MS, Franzblau SG, Fronczek FR, Fischer NH. Antimycobacterial ergosterol-5,8-endoperoxide from Ajuga remota. Planta Medica. 65: 732-4. PMID 10630115 DOI: 10.1055/S-1999-14053 |
0.38 |
|
| 1999 |
Rugutt JK, Henry CW, Franzblau SG, Warner IM. NMR and molecular mechanics study of pyrethrins I and II Journal of Agricultural and Food Chemistry. 47: 3402-3410. PMID 10552664 DOI: 10.1021/Jf980660B |
0.341 |
|
| 1999 |
Valcic S, Montenegro G, Mujica AM, Avila G, Franzblau S, Singh MP, Maiese WM, Timmermann BN. Phytochemical, morphological, and biological investigations of propolis from Central Chile. Zeitschrift FüR Naturforschung. C, Journal of Biosciences. 54: 406-16. PMID 10431392 DOI: 10.1515/Znc-1999-5-617 |
0.384 |
|
| 1999 |
Adams LB, Sinha I, Franzblau SG, Krahenbuhl JL, Mehta RT. Effective treatment of acute and chronic murine tuberculosis with liposome-encapsulated clofazimine. Antimicrobial Agents and Chemotherapy. 43: 1638-43. PMID 10390215 DOI: 10.1128/Aac.43.7.1638 |
0.309 |
|
| 1999 |
Cantrell CL, Abate L, Fronczek FR, Franzblau SG, Quijano L, Fischer NH. Antimycobacterial eudesmanolides from Inula helenium and Rudbeckia subtomentosa. Planta Medica. 65: 351-5. PMID 10364842 DOI: 10.1055/S-1999-14001 |
0.367 |
|
| 1999 |
Cantrell CL, Rajab MS, Franzblau SG, Fischer NH. Antimycobacterial triterpenes from Melia volkensii. Journal of Natural Products. 62: 546-8. PMID 10217705 DOI: 10.1021/Np980288U |
0.377 |
|
| 1998 |
Cantrell CL, Fischer NH, Urbatsch L, McGuire MS, Franzblau SG. Antimycobacterial crude plant extracts from South, Central, and North America. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 5: 137-45. PMID 23195767 DOI: 10.1016/S0944-7113(98)80011-1 |
0.395 |
|
| 1998 |
Davis MC, Franzblau SG, Martin AR. Syntheses and evaluation of benzodiazaborine compounds against M. tuberculosis H37Rv in vitro. Bioorganic & Medicinal Chemistry Letters. 8: 843-6. PMID 9871552 DOI: 10.1016/S0960-894X(98)00126-7 |
0.421 |
|
| 1998 |
Lu T, Cantrell CL, Robbs SL, Franzblau SG, Fischer NH. Antimycobacterial matricaria esters and lactones from Astereae species. Planta Medica. 64: 665-7. PMID 9810277 DOI: 10.1055/S-2006-957547 |
0.334 |
|
| 1998 |
Cantrell CL, Nuñez IS, Castañeda-Acosta J, Foroozesh M, Fronczek FR, Fischer NH, Franzblau SG. Antimycobacterial activities of dehydrocostus lactone and its oxidation products. Journal of Natural Products. 61: 1181-6. PMID 9784148 DOI: 10.1021/Np970333I |
0.313 |
|
| 1998 |
Fischer NH, Lu T, Cantrell CL, Castañeda-Acosta J, Quijano L, Franzblau SG. Antimycobacterial evaluation of germacranolides. Phytochemistry. 49: 559-64. PMID 9747541 DOI: 10.1016/S0031-9422(98)00253-2 |
0.412 |
|
| 1998 |
Wächter GA, Franzblau SG, Montenegro G, Suarez E, Fortunato RH, Saavedra E, Timmermann BN. A new antitubercular mulinane diterpenoid from Azorella madreporica Clos Journal of Natural Products. 61: 965-968. PMID 9677287 DOI: 10.1021/Np980066W |
0.407 |
|
| 1998 |
Collins LA, Torrero MN, Franzblau SG. Green fluorescent protein reporter microplate assay for high-throughput screening of compounds against Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy. 42: 344-7. PMID 9527783 DOI: 10.1128/Aac.42.2.344 |
0.401 |
|
| 1998 |
Franzblau SG, Witzig RS, McLaughlin JC, Torres P, Madico G, Hernandez A, Degnan MT, Cook MB, Quenzer VK, Ferguson RM, Gilman RH. Rapid, low-technology MIC determination with clinical Mycobacterium tuberculosis isolates by using the microplate Alamar Blue assay. Journal of Clinical Microbiology. 36: 362-6. PMID 9466742 DOI: 10.1128/Jcm.36.2.362-366.1998 |
0.37 |
|
| 1998 |
Hiserodt RD, Franzblau SG, Rosen RT. Isolation of 6-, 8-, and 10-Gingerol from Ginger Rhizome by HPLC and Preliminary Evaluation of Inhibition of Mycobacterium aviumand Mycobacterium tuberculosis Journal of Agricultural and Food Chemistry. 46: 2504-2508. |
0.356 |
|
| 1997 |
Collins LA, Franzblau SG. Microplate Alamar blue assay versus BACTEC 460 system for high- throughput screening of compounds against Mycobacterium tuberculosis and Mycobacterium avium Antimicrobial Agents and Chemotherapy. 41: 1004-1009. PMID 9145860 DOI: 10.1128/Aac.41.5.1004 |
0.453 |
|
| 1996 |
Cantrell CL, Lu T, Fronczek FR, Fischer NH, Adams LB, Franzblau SG. Antimycobacterial cycloartanes from Borrichia frutescens. Journal of Natural Products. 59: 1131-6. PMID 8988597 DOI: 10.1021/Np960551W |
0.338 |
|
| 1995 |
Tiansheng Lu, Vargas D, Franzblau SG, Fischer NH. Diterpenes from Solidago rugosa Phytochemistry. 38: 451-456. PMID 7772306 DOI: 10.1016/0031-9422(94)00625-4 |
0.388 |
|
| 1994 |
Tiansheng L, Cantrell CL, Vargas D, Fronczek FR, Franzblau SG, Fischer NH. Terpenes from Liatris ohlingerae Phytochemistry. 37: 1295-1299. DOI: 10.1016/S0031-9422(00)90401-1 |
0.332 |
|
| 1993 |
Witzig RS, Franzblau SG. Susceptibility of Mycobacterium kansasii to ofloxacin, sparfloxacin, clarithromycin, azithromycin, and fusidic acid Antimicrobial Agents and Chemotherapy. 37: 1997-1999. PMID 8239620 DOI: 10.1128/Aac.37.9.1997 |
0.308 |
|
| 1992 |
Franzblau SG, Biswas AN, Harris EB. Fusidic acid is highly active against extracellular and intracellular Mycobacterium leprae Antimicrobial Agents and Chemotherapy. 36: 92-94. PMID 1590706 DOI: 10.1128/Aac.36.1.92 |
0.359 |
|
| 1991 |
Franzblau SG. In vitro activities of aminoglycosides, lincosamides, and rifamycins against Mycobacterium leprae Antimicrobial Agents and Chemotherapy. 35: 1232-1234. PMID 1929269 DOI: 10.1128/Aac.35.6.1232 |
0.378 |
|
| 1991 |
Ramasesh N, Adams LB, Franzblau SG, Krahenbuhl JL. Effects of activated macrophages on Mycobacterium leprae Infection and Immunity. 59: 2864-2869. PMID 1908824 DOI: 10.1128/Iai.59.9.2864-2869.1991 |
0.358 |
|
| 1990 |
FranzBLau SG, White KE. Comparative in vitro activities of 20 fluoroquinolones against Mycobacterium leprae Antimicrobial Agents and Chemotherapy. 34: 229-231. PMID 2183714 DOI: 10.1128/Aac.34.2.229 |
0.33 |
|
| 1989 |
Franzblau SG. Drug susceptibility testing of Mycobacterium leprae in the BACTEC 460 system Antimicrobial Agents and Chemotherapy. 33: 2115-2117. PMID 2694952 DOI: 10.1128/Aac.33.12.2115 |
0.369 |
|
| 1989 |
Franzblau SG, White KE, O'Sullivan JF. Structure-activity relationships of tetramethylpiperidine-substituted phenazines against Mycobacterium leprae in vitro Antimicrobial Agents and Chemotherapy. 33: 2004-2005. PMID 2692516 DOI: 10.1128/Aac.33.11.2004 |
0.371 |
|
| 1988 |
Franzblau SG, Hastings RC. In vitro and in vivo activities of macrolides against Mycobacterium leprae Antimicrobial Agents and Chemotherapy. 32: 1758-1762. PMID 3072920 DOI: 10.1128/Aac.32.12.1758 |
0.36 |
|
| 1988 |
Franzblau SG, O'Sullivan JF. Structure-activity relationships of selected phenazines against Mycobacterium leprae in vitro Antimicrobial Agents and Chemotherapy. 32: 1583-1585. PMID 3056241 DOI: 10.1128/Aac.32.10.1583 |
0.401 |
|
| 1987 |
Sibling LD, Franzblau SG, Krahenbuhl JL. Intracellular fate of Mycobacterium leprae in normal and activated mouse macrophages Infection and Immunity. 55: 680-685. PMID 3546136 DOI: 10.1128/Iai.55.3.680-685.1987 |
0.305 |
|
| 1987 |
Franzblau SG, Hastings RC. Rapid in vitro metabolic screen for antileprosy compounds Antimicrobial Agents and Chemotherapy. 31: 780-783. PMID 3300539 DOI: 10.1128/Aac.31.5.780 |
0.415 |
|
| 1987 |
Franzblau SG, Harris EB, Hastings RC. Axenic incorporation of [U-14C]palmitic acid into the phenolic glycolipid-I ofMycobacterium leprae Fems Microbiology Letters. 48: 407-411. DOI: 10.1111/J.1574-6968.1987.Tb02633.X |
0.307 |
|
| 1986 |
Franzblau SG, Cross C. Comparative in vitro antimicrobial activity of chinese medicinal herbs Journal of Ethnopharmacology. 15: 279-288. PMID 3724208 DOI: 10.1016/0378-8741(86)90166-2 |
0.351 |
|
| 1986 |
Franzblau SG, Takeda T, Nakamura M. Mycobacterial plasmids: Screening and possible relationship to antibiotic resistance in Mycobacterium avium/Mycobacterium intracellulare Microbiology and Immunology. 30: 903-907. PMID 3540539 DOI: 10.1111/J.1348-0421.1986.Tb03017.X |
0.323 |
|
| 1985 |
Franzblau SG, Jimenez DR, Sinclair NA. A Selective Medium for the Isolation of Opportunistic Flavobacteria from Potable Water Journal of Environmental Science and Health . Part a: Environmental Science and Engineering. 20: 583-591. DOI: 10.1080/10934528509375243 |
0.656 |
|
| 1984 |
Franzblau SG, Hinnebusch BJ, Kelley LM, Sinclair NA. Effect of noncoliforms on coliform detection in potable groundwater. Improved recovery with an anaerobic membrane filter technique Applied and Environmental Microbiology. 48: 142-148. PMID 6383216 DOI: 10.1128/Aem.48.1.142-148.1984 |
0.652 |
|
| 1983 |
Franzblau SG, Sinclair NA. Induction of pyruvate decarboxylase in Candida utilis Mycopathologia. 83: 29-33. PMID 6685227 DOI: 10.1007/Bf00437410 |
0.669 |
|
| 1983 |
Franzblau SG, Sinclair NA. Induction of fermentation in Crabtree-negative yeasts Mycopathologia. 82: 185-190. DOI: 10.1007/Bf00439225 |
0.67 |
|
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