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Karl Herold, M.D., Ph.D. - Publications

Affiliations: 
Anesthesiology Cornell University, Ithaca, NY, United States 
Area:
Neuropharmacology, Ion channels
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24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Hollingworth D, Herold KF, Kelly G, Mykhaylyk VB, Xiang J, Zhang D, Wallace BA, Hemmings HC. Functionally important binding site for a volatile anesthetic in a voltage-gated sodium channel identified by X-ray crystallography. Biorxiv : the Preprint Server For Biology. PMID 39574657 DOI: 10.1101/2024.11.04.621342  0.563
2023 Eastman RT, Rusinova R, Herold KF, Huang XP, Dranchak P, Voss TC, Rana S, Shrimp JH, White AD, Hemmings HC, Roth BL, Inglese J, Andersen OS, Dahlin JL. Nonspecific membrane bilayer perturbations by ivermectin underlie SARS-CoV-2 in vitro activity. Biorxiv : the Preprint Server For Biology. PMID 37961094 DOI: 10.1101/2023.10.23.563088  0.529
2019 Zhou C, Johnson KW, Herold KF, Hemmings HC. Differential Inhibition of Neuronal Sodium Channel Subtypes by the General Anesthetic Isoflurane. The Journal of Pharmacology and Experimental Therapeutics. PMID 30792243 DOI: 10.1124/jpet.118.254938  0.545
2017 Johnson KW, Herold KF, Milner TA, Hemmings HC, Platholi J. Sodium channel subtypes are differentially localized to pre- and post-synaptic sites in rat hippocampus. The Journal of Comparative Neurology. PMID 28758202 DOI: 10.1002/Cne.24291  0.641
2017 Herold KF, Andersen OS, Hemmings HC. Divergent effects of anesthetics on lipid bilayer properties and sodium channel function. European Biophysics Journal : Ebj. PMID 28695248 DOI: 10.1007/S00249-017-1239-1  0.603
2017 Sand RM, Gingrich KJ, Macharadze T, Herold KF, Hemmings HC. Isoflurane modulates activation and inactivation gating of the prokaryotic Na(+) channel NaChBac. The Journal of General Physiology. PMID 28416648 DOI: 10.1085/Jgp.201611600  0.577
2017 Herold KF, Sanford RL, Lee W, Andersen OS, Hemmings HC. Clinical concentrations of chemically diverse general anesthetics minimally affect lipid bilayer properties. Proceedings of the National Academy of Sciences of the United States of America. PMID 28265069 DOI: 10.1073/Pnas.1611717114  0.573
2017 Herold K, Lee W, Sanford R, Andersen OS, Hemmings HC. General Anesthetics Minimally affect Lipid Bilayer Properties at Clinical Concentrations Biophysical Journal. 112: 227a. DOI: 10.1016/J.Bpj.2016.11.1249  0.591
2015 Purtell K, Gingrich KJ, Ouyang W, Herold KF, Hemmings HC. Activity-dependent depression of neuronal sodium channels by the general anaesthetic isoflurane. British Journal of Anaesthesia. 115: 112-21. PMID 26089447 DOI: 10.1093/Bja/Aev203  0.57
2014 Herold KF, Sanford RL, Lee W, Schultz MF, Ingólfsson HI, Andersen OS, Hemmings HC. Volatile anesthetics inhibit sodium channels without altering bulk lipid bilayer properties. The Journal of General Physiology. 144: 545-60. PMID 25385786 DOI: 10.1085/Jgp.201411172  0.598
2014 Platholi J, Herold KF, Hemmings HC, Halpain S. Isoflurane reversibly destabilizes hippocampal dendritic spines by an actin-dependent mechanism. Plos One. 9: e102978. PMID 25068870 DOI: 10.1371/Journal.Pone.0102978  0.642
2014 Ingólfsson HI, Thakur P, Herold KF, Hobart EA, Ramsey NB, Periole X, de Jong DH, Zwama M, Yilmaz D, Hall K, Maretzky T, Hemmings HC, Blobel C, Marrink SJ, Koçer A, et al. Phytochemicals perturb membranes and promiscuously alter protein function. Acs Chemical Biology. 9: 1788-98. PMID 24901212 DOI: 10.1021/Cb500086E  0.529
2014 Herold KF, Lee W, Sanford RL, Andersen OS, Hemmings HC. General Anesthetics do not Alter Lipid Bilayer Properties at Clinically Relevant Concentrations Biophysical Journal. 106: 515a. DOI: 10.1016/J.Bpj.2013.11.2877  0.58
2014 Purtell K, Herold KF, Ouyang W, Gingrich KJ, Hemmings HC. Frequency-Dependent Inhibition of Sodium Channels by the General Anesthetic Isoflurane Biophysical Journal. 106: 325a. DOI: 10.1016/J.Bpj.2013.11.1870  0.578
2013 Jevtovic-Todorovic V, Absalom AR, Blomgren K, Brambrink A, Crosby G, Culley DJ, Fiskum G, Giffard RG, Herold KF, Loepke AW, Ma D, Orser BA, Planel E, Slikker W, Soriano SG, et al. Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar. British Journal of Anaesthesia. 111: 143-51. PMID 23722106 DOI: 10.1093/Bja/Aet177  0.476
2013 Tibbs GR, Rowley TJ, Sanford RL, Herold KF, Proekt A, Hemmings HC, Andersen OS, Goldstein PA, Flood PD. HCN1 channels as targets for anesthetic and nonanesthetic propofol analogs in the amelioration of mechanical and thermal hyperalgesia in a mouse model of neuropathic pain. The Journal of Pharmacology and Experimental Therapeutics. 345: 363-73. PMID 23549867 DOI: 10.1124/Jpet.113.203620  0.557
2013 Ingólfsson HI, Thakur P, Herold KF, Maretzky T, Hall K, Zwama M, Yilmaz D, Hemmings HC, Blobel C, Koçer A, Sack J, Andersen OS. Phytochemicals Promiscuously Alter Membrane Protein Function and Bilayer Properties Biophysical Journal. 104: 93a. DOI: 10.1016/J.Bpj.2012.11.557  0.55
2013 Herold KF, Lee W, Sanford RL, Eger EI, Andersen OS, Hemmings HC. Combined Stopped-Flow and Electrophysiological Experiments Suggest Direct Sodium Channel Inhibition by Model Fluorobenzene Anesthetics Biophysical Journal. 104: 427a-428a. DOI: 10.1016/J.Bpj.2012.11.2379  0.602
2013 Hudson AE, Herold KF, Hemmings HC. Pharmacology of Inhaled Anesthetics Pharmacology and Physiology For Anesthesia: Foundations and Clinical Application. 159-179. DOI: 10.1016/B978-1-4377-1679-5.00010-7  0.445
2012 Herold KF, Hemmings HC. Sodium channels as targets for volatile anesthetics. Frontiers in Pharmacology. 3: 50. PMID 22479247 DOI: 10.3389/fphar.2012.00050  0.61
2011 Rusinova R, Herold KF, Sanford RL, Greathouse DV, Hemmings HC, Andersen OS. Thiazolidinedione insulin sensitizers alter lipid bilayer properties and voltage-dependent sodium channel function: implications for drug discovery. The Journal of General Physiology. 138: 249-70. PMID 21788612 DOI: 10.1085/Jgp.201010529  0.581
2010 Rusinova R, Herold KF, Koeppe RE, Hemmings H, Andersen OS. Thiazolidinediones Alter Lipid Bilayer Properties and Native Voltage-Gated Sodium Channel Function Biophysical Journal. 98: 480a. DOI: 10.1016/J.Bpj.2009.12.2612  0.596
2009 Herold KF, Nau C, Ouyang W, Hemmings HC. Isoflurane inhibits the tetrodotoxin-resistant voltage-gated sodium channel Nav1.8. Anesthesiology. 111: 591-9. PMID 19672182 DOI: 10.1097/ALN.0b013e3181af64d4  0.561
2009 Ouyang W, Herold KF, Hemmings HC. Comparative effects of halogenated inhaled anesthetics on voltage-gated Na+ channel function. Anesthesiology. 110: 582-90. PMID 19225394 DOI: 10.1097/ALN.0b013e318197941e  0.557
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