David Wallach - Publications

Affiliations: 
Biological Chemistry Weizmann Institute of Science, Rehovot, Israel 
Area:
Biochemistry, Organic Chemistry

127 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Vitale I, Pietrocola F, Guilbaud E, Aaronson SA, Abrams JM, Adam D, Agostini M, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Aqeilan RI, Arama E, Baehrecke EH, ... ... Wallach D, et al. Apoptotic cell death in disease-Current understanding of the NCCD 2023. Cell Death and Differentiation. PMID 37100955 DOI: 10.1038/s41418-023-01153-w  0.341
2018 Wallach D, Kang TB. Programmed Cell Death in Immune Defense: Knowledge and Presumptions. Immunity. 49: 19-32. PMID 30021143 DOI: 10.1016/J.Immuni.2018.06.019  0.352
2018 Kang TB, Jeong JS, Yang SH, Kovalenko A, Wallach D. Caspase-8 deficiency in mouse embryos triggers chronic RIPK1-dependent activation of inflammatory genes, independently of RIPK3. Cell Death and Differentiation. PMID 29666472 DOI: 10.1038/S41418-018-0104-9  0.463
2018 Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, ... ... Wallach D, et al. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell Death and Differentiation. PMID 29362479 DOI: 10.1038/S41418-017-0012-4  0.421
2018 Gyrd-Hansen M, Farkas T, Fehrenbacher N, Bastholm L, Høyer-Hansen M, Elling F, Wallach D, Flavell R, Kroemer G, Nylandsted J, Jäättelä M. Correction for Gyrd-Hansen et al., "Apoptosome-Independent Activation of the Lysosomal Cell Death Pathway by Caspase-9". Molecular and Cellular Biology. 38. PMID 29288151 DOI: 10.1128/Mcb.00563-17  0.367
2017 Boege Y, Malehmir M, Healy ME, Bettermann K, Lorentzen A, Vucur M, Ahuja AK, Böhm F, Mertens JC, Shimizu Y, Frick L, Remouchamps C, Mutreja K, Kähne T, Sundaravinayagam D, ... ... Wallach D, et al. A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development. Cancer Cell. 32: 342-359.e10. PMID 28898696 DOI: 10.1016/J.Ccell.2017.08.010  0.349
2017 Wallach D. The Tumor Necrosis Factor Family: Family Conventions and Private Idiosyncrasies. Cold Spring Harbor Perspectives in Biology. PMID 28847899 DOI: 10.1101/Cshperspect.A028431  0.341
2017 Yoon S, Kovalenko A, Bogdanov K, Wallach D. MLKL, the Protein that Mediates Necroptosis, Also Regulates Endosomal Trafficking and Extracellular Vesicle Generation. Immunity. PMID 28666573 DOI: 10.1016/J.Immuni.2017.06.001  0.36
2016 Wallach D, Kang TB, Dillon CP, Green DR. Programmed necrosis in inflammation: Toward identification of the effector molecules. Science (New York, N.Y.). 352: aaf2154. PMID 27034377 DOI: 10.1126/Science.Aaf2154  0.439
2016 Wallach D. The cybernetics of TNF: Old views and newer ones. Seminars in Cell & Developmental Biology. 50: 105-14. PMID 26474540 DOI: 10.1016/J.Semcdb.2015.10.014  0.405
2016 Yoon S, Bogdanov K, Kovalenko A, Wallach D. Necroptosis is preceded by nuclear translocation of the signaling proteins that induce it Cell Death and Differentiation. 23: 253-260. DOI: 10.1038/Cdd.2015.92  0.411
2014 Kang TB, Yang SH, Toth B, Kovalenko A, Wallach D. Activation of the NLRP3 inflammasome by proteins that signal for necroptosis. Methods in Enzymology. 545: 67-81. PMID 25065886 DOI: 10.1016/B978-0-12-801430-1.00003-2  0.453
2014 Wallach D, Kovalenko A. Keeping inflammation at bay. Elife. 3: e02583. PMID 24668174 DOI: 10.7554/Elife.02583  0.377
2014 Wallach D, Kang TB, Yang SH, Kovalenko A. The in vivo significance of necroptosis: lessons from exploration of caspase-8 function. Cytokine & Growth Factor Reviews. 25: 157-65. PMID 24411566 DOI: 10.1016/J.Cytogfr.2013.12.001  0.457
2014 Wallach D, Kang TB, Kovalenko A. Concepts of tissue injury and cell death in inflammation: a historical perspective. Nature Reviews. Immunology. 14: 51-9. PMID 24336099 DOI: 10.1038/Nri3561  0.392
2013 Wallach D. The TNF cytokine family: one track in a road paved by many. Cytokine. 63: 225-9. PMID 23792010 DOI: 10.1016/J.Cyto.2013.05.027  0.4
2013 Wallach D, Kovalenko A. Phosphorylation and dephosphorylation of the RIG-I-like receptors: a safety latch on a fateful pathway. Immunity. 38: 402-3. PMID 23521878 DOI: 10.1016/J.Immuni.2013.02.014  0.313
2013 Kang TB, Yang SH, Toth B, Kovalenko A, Wallach D. Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome. Immunity. 38: 27-40. PMID 23260196 DOI: 10.1016/J.Immuni.2012.09.015  0.517
2012 Dillon CP, Oberst A, Weinlich R, Janke LJ, Kang TB, Ben-Moshe T, Mak TW, Wallach D, Green DR. Survival function of the FADD-CASPASE-8-cFLIP(L) complex. Cell Reports. 1: 401-7. PMID 22675671 DOI: 10.1016/J.Celrep.2012.03.010  0.766
2011 Wallach D, Kovalenko A, Kang TB. 'Necrosome'-induced inflammation: must cells die for it? Trends in Immunology. 32: 505-9. PMID 21890409 DOI: 10.1016/J.It.2011.07.004  0.483
2011 Rajput A, Kovalenko A, Bogdanov K, Yang SH, Kang TB, Kim JC, Du J, Wallach D. RIG-I RNA helicase activation of IRF3 transcription factor is negatively regulated by caspase-8-mediated cleavage of the RIP1 protein. Immunity. 34: 340-51. PMID 21419663 DOI: 10.1016/J.Immuni.2010.12.018  0.703
2011 Rajput A, Kang TB, Bogdanov K, Kim JC, Ben-Moshe T, Kovalenko A, Wallach D. Anti-inflammatory functions of caspase-8. Advances in Experimental Medicine and Biology. 691: 253-60. PMID 21153328 DOI: 10.1007/978-1-4419-6612-4_25  0.792
2010 Wallach D, Kang TB, Rajput A, Kim JC, Bogdanov K, Yang SH, Kovalenko A. Anti-inflammatory functions of the "apoptotic" caspases. Annals of the New York Academy of Sciences. 1209: 17-22. PMID 20958311 DOI: 10.1111/J.1749-6632.2010.05742.X  0.731
2010 Wallach D, Rajput A, Kang T, Kim J, Bogdanov K, Yang S, Kovalenko A. SS8-1 The ‘apoptotic’ caspases as regulators of inflammation: new lessons from the study of caspase-8 function Cytokine. 52: 74. DOI: 10.1016/J.Cyto.2010.07.307  0.695
2009 Kovalenko A, Kim JC, Kang TB, Rajput A, Bogdanov K, Dittrich-Breiholz O, Kracht M, Brenner O, Wallach D. Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease. The Journal of Experimental Medicine. 206: 2161-77. PMID 19720838 DOI: 10.1084/Jem.20090616  0.719
2009 Wallach D, Kovalenko A. 12th international TNF conference: the good, the bad and the scientists. Cytokine & Growth Factor Reviews. 20: 259-69. PMID 19665421 DOI: 10.1016/J.Cytogfr.2009.07.008  0.405
2009 Scharner D, Rössig L, Carmona G, Chavakis E, Urbich C, Fischer A, Kang TB, Wallach D, Chiang YJ, Deribe YL, Dikic I, Zeiher AM, Dimmeler S. Caspase-8 is involved in neovascularization-promoting progenitor cell functions. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 571-8. PMID 19122169 DOI: 10.1161/Atvbaha.108.182006  0.407
2009 Kovalenko A, Rajput A, Kim J, Kang T, Bogdanov K, Dittrich-Breiholz O, Kracht M, Brenner O, Wallach D. Caspase-8 regulates cellular response to pattern recognition receptors and prevents spontaneous triggering of chronic inflammation by their endogenous activators Cytokine. 48: 23. DOI: 10.1016/J.Cyto.2009.07.091  0.686
2008 Wallach D, Kovalenko A. Self-termination of the terminator. Nature Immunology. 9: 1325-7. PMID 19008929 DOI: 10.1038/Ni1208-1325  0.302
2008 Wallach D, Kang TB, Kovalenko A. The extrinsic cell death pathway and the élan mortel. Cell Death and Differentiation. 15: 1533-41. PMID 18794887 DOI: 10.1038/cdd.2008.41  0.326
2008 Kang TB, Oh GS, Scandella E, Bolinger B, Ludewig B, Kovalenko A, Wallach D. Mutation of a self-processing site in caspase-8 compromises its apoptotic but not its nonapoptotic functions in bacterial artificial chromosome-transgenic mice. Journal of Immunology (Baltimore, Md. : 1950). 181: 2522-32. PMID 18684943 DOI: 10.4049/Jimmunol.181.4.2522  0.464
2008 Krelin Y, Zhang L, Kang TB, Appel E, Kovalenko A, Wallach D. Caspase-8 deficiency facilitates cellular transformation in vitro. Cell Death and Differentiation. 15: 1350-5. PMID 18566604 DOI: 10.1038/cdd.2008.88  0.315
2008 Ben Moshe T, Kang TB, Kovalenko A, Barash H, Abramovitch R, Galun E, Wallach D. Cell-autonomous and non-cell-autonomous functions of caspase-8. Cytokine & Growth Factor Reviews. 19: 209-17. PMID 18555200 DOI: 10.1016/J.Cytogfr.2008.04.012  0.415
2007 Hövelmeyer N, Wunderlich FT, Massoumi R, Jakobsen CG, Song J, Wörns MA, Merkwirth C, Kovalenko A, Aumailley M, Strand D, Brüning JC, Galle PR, Wallach D, Fässler R, Waisman A. Regulation of B cell homeostasis and activation by the tumor suppressor gene CYLD. The Journal of Experimental Medicine. 204: 2615-27. PMID 17923499 DOI: 10.1084/Jem.20070318  0.385
2007 Peter ME, Budd RC, Desbarats J, Hedrick SM, Hueber AO, Newell MK, Owen LB, Pope RM, Tschopp J, Wajant H, Wallach D, Wiltrout RH, Zörnig M, Lynch DH. The CD95 receptor: apoptosis revisited. Cell. 129: 447-50. PMID 17482535 DOI: 10.1016/J.Cell.2007.04.031  0.374
2007 Ben Moshe T, Barash H, Kang TB, Kim JC, Kovalenko A, Gross E, Schuchmann M, Abramovitch R, Galun E, Wallach D. Role of caspase-8 in hepatocyte response to infection and injury in mice. Hepatology (Baltimore, Md.). 45: 1014-24. PMID 17385212 DOI: 10.1002/Hep.21495  0.592
2007 Kang T, Kovalenko A, Kim J, Oh G, Ben-Moshe T, Rajput A, Wallach D. 69 Structure–Function Analysis In Vivo of Cytokine-Mediated Cell-Death Induction: BAC Transgenic Mice of Caspase-8 Mutants Cytokine. 39: 19-20. DOI: 10.1016/J.Cyto.2007.07.074  0.772
2006 Gyrd-Hansen M, Farkas T, Fehrenbacher N, Bastholm L, Høyer-Hansen M, Elling F, Wallach D, Flavell R, Kroemer G, Nylandsted J, Jäättelä M. Apoptosome-independent activation of the lysosomal cell death pathway by caspase-9. Molecular and Cellular Biology. 26: 7880-91. PMID 16966373 DOI: 10.1128/Mcb.00716-06  0.489
2006 Kovalenko A, Wallach D. If the prophet does not come to the mountain: dynamics of signaling complexes in NF-kappaB activation. Molecular Cell. 22: 433-6. PMID 16713572 DOI: 10.1016/J.Molcel.2006.05.002  0.315
2006 Wei SH, Ming-Lum A, Liu Y, Wallach D, Ong CJ, Chung SW, Moore KW, Mui AL. Proteasome-mediated proteolysis of the interleukin-10 receptor is important for signal downregulation. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 26: 281-90. PMID 16689656 DOI: 10.1089/Jir.2006.26.281  0.311
2006 Helfer B, Boswell BC, Finlay D, Cipres A, Vuori K, Bong Kang T, Wallach D, Dorfleutner A, Lahti JM, Flynn DC, Frisch SM. Caspase-8 promotes cell motility and calpain activity under nonapoptotic conditions. Cancer Research. 66: 4273-8. PMID 16618751 DOI: 10.1158/0008-5472.Can-05-4183  0.468
2006 Sánchez-Valdepeñas C, Martín AG, Ramakrishnan P, Wallach D, Fresno M. NF-kappaB-inducing kinase is involved in the activation of the CD28 responsive element through phosphorylation of c-Rel and regulation of its transactivating activity. Journal of Immunology (Baltimore, Md. : 1950). 176: 4666-74. PMID 16585559 DOI: 10.4049/Jimmunol.176.8.4666  0.311
2005 Wallach D. Probing cell death by chemical screening. Nature Chemical Biology. 1: 68-9. PMID 16407999 DOI: 10.1038/Nchembio0705-68  0.398
2004 Ramakrishnan P, Wang W, Wallach D. Receptor-specific signaling for both the alternative and the canonical NF-kappaB activation pathways by NF-kappaB-inducing kinase. Immunity. 21: 477-89. PMID 15485626 DOI: 10.1016/J.Immuni.2004.08.009  0.365
2004 Kang TB, Ben-Moshe T, Varfolomeev EE, Pewzner-Jung Y, Yogev N, Jurewicz A, Waisman A, Brenner O, Haffner R, Gustafsson E, Ramakrishnan P, Lapidot T, Wallach D. Caspase-8 serves both apoptotic and nonapoptotic roles. Journal of Immunology (Baltimore, Md. : 1950). 173: 2976-84. PMID 15322156 DOI: 10.4049/Jimmunol.173.5.2976  0.774
2004 Xanthoulea S, Pasparakis M, Kousteni S, Brakebusch C, Wallach D, Bauer J, Lassmann H, Kollias G. Tumor necrosis factor (TNF) receptor shedding controls thresholds of innate immune activation that balance opposing TNF functions in infectious and inflammatory diseases. The Journal of Experimental Medicine. 200: 367-76. PMID 15289505 DOI: 10.1084/Jem.20040435  0.402
2004 Engelmann H, Aderka D, Wallach D. Purification of TNF binding proteins. Methods in Molecular Medicine. 98: 23-32. PMID 15064430 DOI: 10.1385/1-59259-771-8:023  0.356
2004 Greenberger S, Shaish A, Varda-Bloom N, Levanon K, Breitbart E, Goldberg I, Barshack I, Hodish I, Yaacov N, Bangio L, Goncharov T, Wallach D, Harats D. Transcription-controlled gene therapy against tumor angiogenesis. The Journal of Clinical Investigation. 113: 1017-24. PMID 15057308 DOI: 10.1172/Jci20007  0.363
2003 Zalcenstein A, Stambolsky P, Weisz L, Müller M, Wallach D, Goncharov TM, Krammer PH, Rotter V, Oren M. Mutant p53 gain of function: repression of CD95(Fas/APO-1) gene expression by tumor-associated p53 mutants. Oncogene. 22: 5667-76. PMID 12944915 DOI: 10.1038/Sj.Onc.1206724  0.303
2003 Kovalenko A, Chable-Bessia C, Cantarella G, Israël A, Wallach D, Courtois G. The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination. Nature. 424: 801-5. PMID 12917691 DOI: 10.1038/Nature01802  0.405
2003 Schuchmann M, Varfolomeev EE, Hermann F, Rueckert F, Strand D, Koehler H, Strand S, Lohse AW, Wallach D, Galle PR. Dominant negative MORT1/FADD rescues mice from CD95 and TNF-induced liver failure Hepatology. 37: 129-135. PMID 12500197 DOI: 10.1053/Jhep.2003.50011  0.398
2003 Schuchmann M, Rueckert F, Varfolomeev E, Wallach D, Lohse A, Galle P. The role of mort1/FADD in apoptosis and liver regeneration Journal of Hepatology. 38: 20. DOI: 10.1016/S0168-8278(03)80473-7  0.315
2002 Wallach D. Up the down staircase. Nature Immunology. 3: 802-3. PMID 12205467 DOI: 10.1038/Ni0902-802  0.328
2002 Wallach D, Arumugam TU, Boldin MP, Cantarella G, Ganesh KA, Goltsev Y, Goncharov TM, Kovalenko AV, Rajput A, Varfolomeev EE, Zhang SQ. How are the regulators regulated? The search for mechanisms that impose specificity on induction of cell death and NF-kappaB activation by members of the TNF/NGF receptor family. Arthritis Research. 4: S189-96. PMID 12110139 DOI: 10.1186/Ar585  0.666
2000 Zhang SQ, Kovalenko A, Cantarella G, Wallach D. Recruitment of the IKK Signalosome to the p55 TNF Receptor Immunity. 12: 301-311. PMID 10755617 DOI: 10.1016/S1074-7613(00)80183-1  0.399
1999 Holtmann H, Winzen R, Holland P, Eickemeier S, Hoffmann E, Wallach D, Malinin NL, Cooper JA, Resch K, Kracht M. Induction of interleukin-8 synthesis integrates effects on transcription and mRNA degradation from at least three different cytokine- or stress- activated signal transduction pathways Molecular and Cellular Biology. 19: 6742-6753. PMID 10490613 DOI: 10.1128/Mcb.19.10.6742  0.34
1999 Wallach D, Varfolomeev EE, Malinin NL, Goltsev YV, Kovalenko AV, Boldin MP. Tumor necrosis factor receptor and Fas signaling mechanisms. Annual Review of Immunology. 17: 331-67. PMID 10358762 DOI: 10.1146/Annurev.Immunol.17.1.331  0.47
1999 Watts AD, Hunt NH, Wanigasekara Y, Bloomfield G, Wallach D, Roufogalis BD, Chaudhri G. A casein kinase I motif present in the cytoplasmic domain of members of the tumour necrosis factor ligand family is implicated in 'reverse signalling'. The Embo Journal. 18: 2119-26. PMID 10205166 DOI: 10.1093/Emboj/18.8.2119  0.365
1999 Li Y, Kang J, Friedman J, Tarassishin L, Ye J, Kovalenko A, Wallach D, Horwitz MS. Identification of a cell protein (FIP-3) as a modulator of NF-kappaB activity and as a target of an adenovirus inhibitor of tumor necrosis factor alpha-induced apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 96: 1042-7. PMID 9927690 DOI: 10.1073/Pnas.96.3.1042  0.441
1998 Varfolomeev EE, Schuchmann M, Luria V, Chiannilkulchai N, Beckmann JS, Mett IL, Rebrikov D, Brodianski VM, Kemper OC, Kollet O, Lapidot T, Soffer D, Sobe T, Avraham KB, Goncharov T, ... ... Wallach D, et al. Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally. Immunity. 9: 267-76. PMID 9729047 DOI: 10.1016/S1074-7613(00)80609-3  0.479
1998 Sylla BS, Hung SC, Davidson DM, Hatzivassiliou E, Malinin NL, Wallach D, Gilmore TD, Kieff E, Mosialos G. Epstein-Barr virus-transforming protein latent infection membrane protein 1 activates transcription factor NF-kappaB through a pathway that includes the NF-kappaB-inducing kinase and the IkappaB kinases IKKalpha and IKKbeta. Proceedings of the National Academy of Sciences of the United States of America. 95: 10106-11. PMID 9707608 DOI: 10.1073/Pnas.95.17.10106  0.356
1998 Wallach D, Kovalenko AV, Varfolomeev EE, Boldin MP. Death-inducing functions of ligands of the tumor necrosis factor family: a Sanhedrin verdict. Current Opinion in Immunology. 10: 279-88. PMID 9638364 DOI: 10.1016/S0952-7915(98)80166-0  0.423
1998 Wallach D, Boldin MP, Kovalenko AV, Malinin NL, Mett IL, Camonis JH. The yeast two-hybrid screening technique and its use in the study of protein-protein interactions in apoptosis. Current Opinion in Immunology. 10: 131-6. PMID 9602300 DOI: 10.1016/S0952-7915(98)80240-9  0.322
1998 Akiba H, Nakano H, Nishinaka S, Shindo M, Kobata T, Atsuta M, Morimoto C, Ware CF, Malinin NL, Wallach D, Yagita H, Okumura K. CD27, a member of the tumor necrosis factor receptor superfamily, activates NF-kappaB and stress-activated protein kinase/c-Jun N-terminal kinase via TRAF2, TRAF5, and NF-kappaB-inducing kinase. The Journal of Biological Chemistry. 273: 13353-8. PMID 9582383 DOI: 10.1074/Jbc.273.21.13353  0.345
1998 Carpentier I, Declercq W, Malinin NL, Wallach D, Fiers W, Beyaert R. TRAF2 plays a dual role in NF-kappaB-dependent gene activation by mediating the TNF-induced activation of p38 MAPK and IkappaB kinase pathways. Febs Letters. 425: 195-8. PMID 9559646 DOI: 10.1016/S0014-5793(98)00226-9  0.407
1998 Aderka D, Sorkine P, Abu-Abid S, Lev D, Setton A, Cope AP, Wallach D, Klausner J. Shedding kinetics of soluble tumor necrosis factor (TNF) receptors after systemic TNF leaking during isolated limb perfusion. Relevance to the pathophysiology of septic shock Journal of Clinical Investigation. 101: 650-659. PMID 9449699 DOI: 10.1172/Jci694  0.375
1997 Goltsev YV, Kovalenko AV, Arnold E, Varfolomeev EE, Brodianskii VM, Wallach D. CASH, a novel caspase homologue with death effector domains. The Journal of Biological Chemistry. 272: 19641-4. PMID 9289491 DOI: 10.1074/Jbc.272.32.19641  0.442
1997 Wallach D, Boldin M, Varfolomeev E, Beyaert R, Vandenabeele P, Fiers W. Cell death induction by receptors of the TNF family: towards a molecular understanding. Febs Letters. 410: 96-106. PMID 9247131 DOI: 10.1016/S0014-5793(97)00553-X  0.397
1997 Wallach D. Placing death under control Nature. 388: 123. PMID 9217148 DOI: 10.1038/40516  0.428
1997 Wallach D. Cell death induction by TNF: A matter of self control Trends in Biochemical Sciences. 22: 107-109. PMID 9149526 DOI: 10.1016/S0968-0004(97)01015-3  0.368
1997 Malinin NL, Boldin MP, Kovalenko AV, Wallach D. MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1. Nature. 385: 540-4. PMID 9020361 DOI: 10.1038/385540A0  0.397
1996 Wallach D. Suicide by order: Some open questions about the cell-killing activities of the TNF ligand and receptor families Cytokine and Growth Factor Reviews. 7: 211-221. PMID 8971476 DOI: 10.1016/S1359-6101(96)00032-9  0.393
1996 Eliaz R, Wallach D, Kost J. Long-term protection against the effects of tumour necrosis factor by controlled delivery of the soluble p55 TNF receptor. Cytokine. 8: 482-7. PMID 8818545 DOI: 10.1006/Cyto.1996.0065  0.375
1996 Kupferminc MJ, Peaceman AM, Aderka D, Wallach D, Socol ML. Soluble tumor necrosis factor receptors and interleukin-6 levels in patients with severe preeclampsia. Obstetrics and Gynecology. 88: 420-7. PMID 8752252 DOI: 10.1016/0029-7844(96)00179-2  0.31
1996 Boldin MP, Goncharov TM, Goltsev YV, Wallach D. Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death. Cell. 85: 803-15. PMID 8681376 DOI: 10.1016/S0092-8674(00)81265-9  0.449
1996 Varfolomeev EE, Boldin MP, Goncharov TM, Wallach D. A potential mechanism of "cross-talk" between the p55 tumor necrosis factor receptor and Fas/APO1: proteins binding to the death domains of the two receptors also bind to each other. Journal of Experimental Medicine. 183: 1271-1275. PMID 8642271 DOI: 10.1084/Jem.183.3.1271  0.373
1996 Kalinkovich A, Geleziunas R, Kemper O, Belenki D, Wallach D, Wainberg MA, Bentwich Z. Increased soluble tumor necrosis factor receptor expression and release by human immunodeficiency virus type 1 infection. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 15: 749-57. PMID 8536102 DOI: 10.1089/Jir.1995.15.749  0.317
1996 Rossi G, Alijagic S, Schoeler D, Schmitt M, Graf H, Czarnetzki BM, Wallach D. Tumor necrosis factor receptors of the monocyte derived Langerhans cell phenotype "MoLC". Advances in Experimental Medicine and Biology. 378: 129-33. PMID 8526036 DOI: 10.1007/978-1-4615-1971-3_28  0.424
1996 Opsjøn SL, Novick D, Wathen NC, Cope AP, Wallach D, Aderka D. Soluble tumor necrosis factor receptors and soluble interleukin-6 receptor in fetal and maternal sera, coelomic and amniotic fluids in normal and pre-eclamptic pregnancies. Journal of Reproductive Immunology. 29: 119-34. PMID 7500319 DOI: 10.1016/0165-0378(95)00940-M  0.306
1995 Sippy BD, Hofman FM, Wallach D, Hinton DR. Increased expression of tumor necrosis factor-alpha receptors in the brains of patients with AIDS. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association. 10: 511-21. PMID 8548330 DOI: 10.1097/00042560-199510050-00004  0.334
1995 Kuhnert P, Kemper O, Wallach D. Cloning, sequencing and partial functional characterization of the 5' region of the human p75 tumor necrosis factor receptor-encoding gene (TNF-R). Gene. 150: 381-6. PMID 7821811 DOI: 10.1016/0378-1119(94)90457-X  0.337
1995 Porat R, Paddock HN, Schwaitzberg SD, Connolly RJ, Wilkens T, Dasch JR, Gascon MP, Hutchison JS, Ythier A, Wallach D. Glycosylated recombinant human tumor necrosis factor binding protein-1 reduces mortality, shock, and production of tumor necrosis factor in rabbit Escherichia coli sepsis. Critical Care Medicine. 23: 1080-9. PMID 7774220 DOI: 10.1097/00003246-199506000-00014  0.321
1995 Schuchmann M, Hess S, Bufler P, Brakebusch C, Wallach D, Porter A, Riethmüller G, Engelmann H. Functional discrepancies between tumor necrosis factor and lymphotoxin alpha explained by trimer stability and distinct receptor interactions. European Journal of Immunology. 25: 2183-9. PMID 7664782 DOI: 10.1002/Eji.1830250810  0.334
1995 Boldin MP, Mett IL, Wallach D. A protein related to a proteasomal subunit binds to the intracellular domain of the p55 TNF receptor upstream to its 'death domain'. Febs Letters. 367: 39-44. PMID 7601280 DOI: 10.1016/0014-5793(95)00534-G  0.382
1995 Boldin MP, Varfolomeev EE, Pancer Z, Mett IL, Camonis JH, Wallach D. A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain. The Journal of Biological Chemistry. 270: 7795-8. PMID 7536190 DOI: 10.1074/Jbc.270.14.7795  0.388
1995 Boldin MP, Mett IL, Varfolomeev EE, Chumakov I, Shemer-Avni Y, Camonis JH, Wallach D. Self-association of the "death domains" of the p55 tumor necrosis factor (TNF) receptor and Fas/APO1 prompts signaling for TNF and Fas/APO1 effects. The Journal of Biological Chemistry. 270: 387-91. PMID 7529234 DOI: 10.1074/Jbc.270.1.387  0.413
1995 Feinstein E, Kimchi A, Wallach D, Boldin M, Varfolomeev E. The death domain: a module shared by proteins with diverse cellular functions Trends in Biochemical Sciences. 20: 342-344. PMID 7482697 DOI: 10.1016/S0968-0004(00)89070-2  0.325
1994 Molyneux ME, Engelmann H, Taylor TE, Wirima JJ, Aderka D, Wallach D, Grau GE. Circulating plasma receptors for tumour necrosis factor in Malawian children with severe falciparum malaria. Cytokine. 5: 604-9. PMID 8186373 DOI: 10.1016/S1043-4666(05)80011-0  0.303
1994 Ettehadi P, Greaves MW, Wallach D, Aderka D, Camp RD. Elevated tumour necrosis factor-alpha (TNF-alpha) biological activity in psoriatic skin lesions. Clinical and Experimental Immunology. 96: 146-51. PMID 8149659 DOI: 10.1111/J.1365-2249.1994.Tb06244.X  0.312
1994 Ythier A, Gascon MP, Juillard P, Vesin C, Wallach D, Grau GE. Protective effect of natural TNF-binding protein on human TNF-induced toxicity in mice. Cytokine. 5: 459-62. PMID 8142601 DOI: 10.1016/1043-4666(93)90036-5  0.367
1994 Bigda J, Beletsky I, Brakebusch C, Varfolomeev Y, Engelmann H, Holtmann H, Wallach D. Dual role of the p75 tumor necrosis factor (TNF) receptor in TNF cytotoxicity. Journal of Experimental Medicine. 180: 445-460. PMID 7519237 DOI: 10.1084/Jem.180.2.445  0.358
1994 Wallach D, Boldin M, Varfolomeev EE, Bigda Y, Camonis JH, Mett I. Screening for proteins that bind to the intracellular domains of the two tumor necrosis factor receptors (TNF-R) revealed effective self-association of the p55 TNF-R “death domain”, which can trigger signaling Cytokine. 6: 556. DOI: 10.1016/1043-4666(94)90185-6  0.347
1993 Belldegrun A, Pierce W, Sayah D, deKernion J, Wallach D, Aderka D, Figlin RA. Soluble tumor necrosis factor receptor expression in patients with metastatic renal cell carcinoma treated with interleukin-2-based immunotherapy. Journal of Immunotherapy With Emphasis On Tumor Immunology : Official Journal of the Society For Biological Therapy. 13: 175-80. PMID 8385988 DOI: 10.1097/00002371-199304000-00004  0.317
1993 Kemper O, Wallach D. Cloning and partial characterization of the promoter for the human p55 tumor necrosis factor (TNF) receptor Gene. 134: 209-216. PMID 8262379 DOI: 10.1016/0378-1119(93)90095-K  0.341
1993 Miltenburg AMM, Aderka D, Laar JMv, Wallach D, Breedveld FC. Levels of soluble receptors for tumor necrosis factor type I and type II in paired synovial fluids of arthritis patients Rheumatology International. 13: 117-119. PMID 8235290 DOI: 10.1007/Bf00290299  0.302
1993 Cope AP, Gibbons DL, Aderka D, Foxwell BM, Wallach D, Maini RN, Feldmann M, Brennan FM. Differential regulation of tumour necrosis factor receptors (TNF-R) by IL-4; upregulation of P55 and P75 TNF-R on synovial joint mononuclear cells Cytokine. 5: 205-212. PMID 8218932 DOI: 10.1016/1043-4666(93)90006-Q  0.336
1993 Aderka D, Maor Y, Novick D, Engelmann H, Kahn Y, Levo Y, Wallach D, Revel M. Interleukin-6 inhibits the proliferation of B-chronic lymphocytic leukemia cells that is induced by tumor necrosis factor-alpha or -beta Blood. 81: 2076-2084. DOI: 10.1182/Blood.V81.8.2076.2076  0.321
1992 Cope AP, Aderka D, Doherty M, Engelmann H, Gibbons D, Jones AC, Brennan FM, Maini RN, Wallach D, Feldmann M. Increased levels of soluble tumor necrosis factor receptors in the sera and synovial fluid of patients with rheumatic diseases. Arthritis and Rheumatism. 35: 1160-9. PMID 1329774 DOI: 10.1002/Art.1780351008  0.301
1992 Aderka D, Engelmann H, Maor Y, Brakebusch C, Wallach D. Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors. Journal of Experimental Medicine. 175: 323-329. PMID 1310100 DOI: 10.1084/Jem.175.2.323  0.388
1992 Engelmann H, Aderka D, Nophar Y, Kemper O, Brakebusch C, Holtmann H, Wallach D. Soluble and Cell Surface Receptors for Tumor Necrosis Factor Agents and Actions. 35: 359-365. DOI: 10.1007/978-94-015-8070-0_48  0.394
1992 Brakebusch C, Nophar Y, Kemper O, Engelmann H, Wallach D. Cytoplasmic truncation of the p55 tumour necrosis factor (TNF) receptor abolishes signalling, but not induced shedding of the receptor. The Embo Journal. 11: 943-950. DOI: 10.1002/J.1460-2075.1992.Tb05133.X  0.388
1991 Sarov I, Geron E, Shemer-Avni Y, Manor E, Zvillich M, Wallach D, Schmitz E, Holtman H. Implications for persistent chlamydial infections of phagocyte-microorganism interplay. European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology. 10: 119-23. PMID 1907541 DOI: 10.1007/Bf01964423  0.343
1991 Derré J, Kemper O, Cherif D, Nophar Y, Berger R, Wallach D. The gene for the type 1 tumor necrosis factor receptor (TNF-R1) is localized on band 12p13. Human Genetics. 87: 231-3. PMID 1648547 DOI: 10.1007/Bf00204191  0.305
1991 König M, Wallach D, Resch K, Holtmann H. Induction of hyporesponsiveness to an early post-binding effect of tumor necrosis factor by tumor necrosis factor itself and interleukin 1. European Journal of Immunology. 21: 1741-5. PMID 1647957 DOI: 10.1002/Eji.1830210723  0.41
1991 Holtmann H, Brakebusch C, König M, Klocke R, Winzen R, Resch K, Wallach D. Mechanisms controlling the level of receptors for tumor necrosis factor. Agents and Actions. 32: 106-8. PMID 1647647 DOI: 10.1007/Bf01983330  0.307
1990 Novick D, Engelmann H, Wallach D, Leitner O, Revel M, Rubinstein M. Purification of soluble cytokine receptors from normal human urine by ligand-affinity and immunoaffinity chromatography. Journal of Chromatography A. 510: 331-337. PMID 2144854 DOI: 10.1016/S0021-9673(01)93767-7  0.323
1990 Holtmann H, Shemer-Avni Y, Wessel K, Sarov I, Wallach D. Inhibition of growth of Chlamydia trachomatis by tumor necrosis factor is accompanied by increased prostaglandin synthesis. Infection and Immunity. 58: 3168-72. PMID 2119339 DOI: 10.1128/Iai.58.10.3168-3172.1990  0.352
1990 Nophar Y, Kemper O, Brakebusch C, Englemann H, Zwang R, Aderka D, Holtmann H, Wallach D. Soluble forms of tumor necrosis factor receptors (TNF-Rs). The cDNA for the type I TNF-R, cloned using amino acid sequence data of its soluble form, encodes both the cell surface and a soluble form of the receptor. The Embo Journal. 9: 3269-3278. DOI: 10.1002/J.1460-2075.1990.Tb07526.X  0.369
1989 Shemer-Avni Y, Wallach D, Sarov I. Reversion of the antichlamydial effect of tumor necrosis factor by tryptophan and antibodies to beta interferon. Infection and Immunity. 57: 3484-90. PMID 2509363 DOI: 10.1128/Iai.57.11.3484-3490.1989  0.379
1989 Novick D, Engelmann H, Wallach D, Rubinstein M. Soluble cytokine-receptors are present in normal human urine Cytokine. 1: 149. DOI: 10.1016/1043-4666(89)91511-1  0.304
1988 Holtmann H, Hahn T, Wallach D. Interrelated effects of tumor necrosis factor and interleukin 1 on cell viability. Immunobiology. 177: 7-22. PMID 3260211 DOI: 10.1016/S0171-2985(88)80087-1  0.396
1988 Ophir D, Hahn T, Schattner A, Wallach D, Aviel A. Tumor necrosis factor in middle ear effusions. Archives of Otolaryngology--Head & Neck Surgery. 114: 1256-8. PMID 3166755 DOI: 10.1001/Archotol.1988.01860230050021  0.398
1988 Wallach D, Holtmann H, Aderka D, Hahn T, Engelmann H, Nophar Y. Sensitizing effects and mechanisms of desensitization in regulation of the in vivo response to TNF. Annales De L'Institut Pasteur. Immunology. 139: 323-7. PMID 3048317 DOI: 10.1016/0769-2625(88)90150-X  0.332
1988 Aderka D, Levo Y, Ramot B, Michalevicz R, Meytes D, Shaklai M, Hahn T, Holtmann H, Revel M, Wallach D. Reduced production of tumor necrosis factor by mononuclear cells in hairy cell leukemia patients and improvement following interferon therapy. Cancer. 60: 2208-12. PMID 2830954 DOI: 10.1002/1097-0142(19871101)60:9<2208::Aid-Cncr2820600917>3.0.Co;2-8  0.324
1987 Eife R, Müller-wiefel DE, Sigmund B, Mehls O, Engelmann H, Holtmann H, Wallach D. ELEVATED LEVELS OF TUMOR NECROSIS FACTOR (TNF) IN ADOLESCENTS ON HEMODIALYSIS (HD) Pediatric Research. 22: 224-224. DOI: 10.1203/00006450-198708000-00065  0.328
1986 Aderka D, Hahn T, Wallach D. Involvement of cytotoxins in the immune response to viral infection. Antiviral Research. 141-8. PMID 3002253 DOI: 10.1016/S0166-3542(85)80021-8  0.328
1986 Israel S, Hahn T, Holtmann H, Wallach D. Binding of human TNF-alpha to high-affinity cell surface receptors: effect of IFN. Immunology Letters. 12: 217-24. PMID 2424831 DOI: 10.1016/0165-2478(86)90007-6  0.412
1985 Hahn T, Toker L, Budilovsky S, Aderka D, Eshhar Z, Wallach D. Use of monoclonal antibodies to a human cytotoxin for its isolation and for examining the self-induction of resistance to this protein. Proceedings of the National Academy of Sciences of the United States of America. 82: 3814-8. PMID 3889916 DOI: 10.1073/Pnas.82.11.3814  0.336
1985 Aderka D, Novick D, Hahn T, Fischer DG, Wallach D. Increase of vulnerability to lymphotoxin in cells infected by vesicular stomatitis virus and its further augmentation by interferon. Cellular Immunology. 92: 218-25. PMID 2986852 DOI: 10.1016/0008-8749(85)90003-6  0.301
1984 Gazitt Y, Ben-Bassat H, Wallach D, Revel M, Schattner A. Interferon-induced cytotoxicity and (2'-5') oligo(A) synthetase activity in T cells. Differences in responsiveness among T cells from various individuals and among lymphoblastoid T-cell lines. Clinical Immunology and Immunopathology. 30: 71-9. PMID 6607796 DOI: 10.1016/0090-1229(84)90008-4  0.309
1983 Wallach D. The HLA proteins and a related protein of 28 kDa are preferentially induced by interferon-γ human WISH cells European Journal of Immunology. 13: 794-798. PMID 6416868 DOI: 10.1002/Eji.1830131003  0.316
1983 Wallach D. Interferon-lnduced resistance to the killing by NK cells: A preferential effect of IFN-γ Cellular Immunology. 75: 390-395. PMID 6403252 DOI: 10.1016/0008-8749(83)90337-4  0.307
1982 Zor U, Ben-Dori R, Maoz I, Wallach D, Gurari-Rotman D. Inhibition by glucocorticosteroid hormones of interferon and prostaglandin E induction by poly(rI). Poly(rC). Journal of General Virology. 63: 359-363. PMID 6818330 DOI: 10.1099/0022-1317-63-2-359  0.309
1982 Wallach D, Fellous M, Revel M. Preferential effect of gamma interferon on the synthesis of HLA antigens and their mRNAs in human cells. Nature. 299: 833-6. PMID 6290893 DOI: 10.1038/299833A0  0.328
1982 Schattner A, Wallach D, Merlin G, Hahn T, Levin S, Ramot B, Revel M. Variation of (2'-5') oligo A synthetase level in lymphocytes and granulocytes of patients with viral infections and leukemia. Journal of Interferon Research. 2: 355-61. PMID 6182252 DOI: 10.1089/Jir.1982.2.355  0.302
1982 Wallach D. Regulation of susceptibility to natural killer cells' cytotoxicity and regulation on HLA synthesis: Differing efficacies of alpha, beta, and gamma interferons Journal of Interferon Research. 2: 329-338. PMID 6182251 DOI: 10.1089/Jir.1982.2.329  0.351
1979 Wallach D, Revel M. Hormonal protection of interferon-treated cells against double-stranded RNA-induced cytolysis Febs Letters. 101: 364-368. PMID 221265 DOI: 10.1016/0014-5793(79)81045-5  0.351
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