Year |
Citation |
Score |
2019 |
Palacios DS, Meredith EL, Kawanami T, Adams CM, Chen X, Darsigny V, Palermo M, Baird D, George EL, Guy C, Hewett J, Tierney L, Thigale S, Wang L, Weihofen WA. Scaffold Morphing Identifies 3-Pyridyl Azetidine Ureas as Inhibitors of Nicotinamide Phosphoribosyltransferase (NAMPT). Acs Medicinal Chemistry Letters. 10: 1524-1529. PMID 31749905 DOI: 10.1021/Acsmedchemlett.9B00325 |
0.347 |
|
2018 |
Ehara T, Adams CM, Bevan D, Ji N, Meredith EL, Belanger DB, Powers J, Kato M, Solovay C, Liu D, Capparelli M, Bolduc P, Grob JE, Daniels MH, Ferrara L, et al. The Discovery of (S)-1-(6-(3-((4-(1-(Cyclopropanecarbonyl)piperidin-4-yl)-2-methylphenyl)amino)-2,3-dihydro-1H-inden-4-yl)pyridin-2-yl)-5-methyl-1H-pyrazole-4-carboxylic Acid, a Soluble Guanylate Cyclase Activator Specifically Designed for Topical Ocular Delivery as a Therapy for Glaucoma. Journal of Medicinal Chemistry. PMID 29498522 DOI: 10.1021/Acs.Jmedchem.8B00007 |
0.33 |
|
2017 |
Palacios DS, Meredith E, Kawanami T, Adams C, Chen X, Darsigny V, Geno E, Palermo M, Baird D, Boynton G, Busby SA, George EL, Guy C, Hewett J, Tierney L, et al. Structure based design of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors from a phenotypic screen. Bioorganic & Medicinal Chemistry Letters. PMID 29275937 DOI: 10.1016/J.Bmcl.2017.12.037 |
0.31 |
|
2016 |
Mainolfi N, Powers J, Meredith E, Elliott J, Gunderson KG, Poor S, Liu F, Anderson K. Core Replacements in a Potent Series of VEGFR-2 Inhibitors and Their Impact on Potency, Solubility, and hERG. Acs Medicinal Chemistry Letters. 7: 357-62. PMID 27096041 DOI: 10.1021/Acsmedchemlett.6B00018 |
0.362 |
|
2013 |
Meredith EL, Ksander G, Monovich LG, Papillon JP, Liu Q, Miranda K, Morris P, Rao C, Burgis R, Capparelli M, Hu QY, Singh A, Rigel DF, Jeng AY, Beil M, et al. Discovery and in Vivo Evaluation of Potent Dual CYP11B2 (Aldosterone Synthase) and CYP11B1 Inhibitors. Acs Medicinal Chemistry Letters. 4: 1203-7. PMID 24900631 DOI: 10.1021/Ml400324C |
0.337 |
|
2012 |
Johnson L, Powers J, Ma F, Jendza K, Wang B, Meredith E, Mainolfi N. A Reliable Synthesis of 3-Amino-5-Alkyl and 5-Amino-3-Alkyl Isoxazoles Synthesis. 45: 171-173. DOI: 10.1055/S-0032-1317935 |
0.468 |
|
2010 |
Meredith EL, Beattie K, Burgis R, Capparelli M, Chapo J, Dipietro L, Gamber G, Enyedy I, Hood DB, Hosagrahara V, Jewell C, Koch KA, Lee W, Lemon DD, Mckinsey TA, et al. Identification of potent and selective amidobipyridyl inhibitors of protein kinase D Journal of Medicinal Chemistry. 53: 5422-5438. PMID 20684592 DOI: 10.1021/Jm100076W |
0.329 |
|
2005 |
Andrus MB, Hicken EJ, Meredith EL. Chapter 2 Synthesis of geldanamycin using glycolate aldol reactions Strategies and Tactics in Organic Synthesis. 6: 38-70. DOI: 10.1016/S1874-6004(05)80025-5 |
0.741 |
|
2003 |
Andrus MB, Meredith EL, Hicken EJ, Simmons BL, Glancey RR, Ma W. Total synthesis of (+)-geldanamycin and (-)-o-quinogeldanamycin: asymmetric glycolate aldol reactions and biological evaluation. The Journal of Organic Chemistry. 68: 8162-9. PMID 14535799 DOI: 10.1021/Jo034870L |
0.749 |
|
2003 |
Andrus MB, Hicken EJ, Meredith EL, Simmons BL, Cannon JF. Selective synthesis of the para-quinone region of geldanamycin. Organic Letters. 5: 3859-62. PMID 14535728 DOI: 10.1021/Ol035400G |
0.721 |
|
2003 |
Andrus MB, Liu J, Meredith EL, Nartey E. Synthesis of resveratrol using a direct decarbonylative Heck approach from resorcylic acid Tetrahedron Letters. 44: 4819-4822. DOI: 10.1016/S0040-4039(03)01131-6 |
0.617 |
|
2002 |
Andrus MB, Meredith EL, Simmons BL, Soma Sekhar BB, Hicken EJ. Total synthesis of (+)-geldanamycin and (-)-o-quinogeldanamycin with use of asymmetric anti- and syn-glycolate aldol reactions. Organic Letters. 4: 3549-52. PMID 12323066 DOI: 10.1021/Ol0267432 |
0.745 |
|
2002 |
Andrus MB, Mendenhall KG, Meredith EL, Soma Sekhar BBV. Glycolate aldol reactions with boron enolates of bis-4-methoxyphenyl dioxanone Tetrahedron Letters. 43: 1789-1792. DOI: 10.1016/S0040-4039(02)00152-1 |
0.695 |
|
2001 |
Andrus MB, Meredith EL, Sekhar BB. Synthesis of the left-hand portion of geldanamycin using an anti glycolate aldol reaction. Organic Letters. 3: 259-62. PMID 11430049 DOI: 10.1021/Ol0068997 |
0.686 |
|
2001 |
Andrus MB, Soma Sekhar BBV, Turner TM, Meredith EL. Highly selective syn glycolate aldol reactions with boron enolates of Masamune norephedrine esters Tetrahedron Letters. 42: 7197-7201. DOI: 10.1016/S0040-4039(01)01521-0 |
0.752 |
|
2000 |
Andrus MB, Sekhar BB, Meredith EL, Dalley NK. Anti-selective glycolate aldol additions with an oxapyrone boron enolate. Organic Letters. 2: 3035-7. PMID 10986101 DOI: 10.1021/Ol0002166 |
0.698 |
|
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