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Allen F. Brooks, Ph.D. - Publications

Affiliations: 
2012 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Organic Chemistry, Biochemistry
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49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Kaur T, Brooks AF, Liddell KM, Henderson BD, Hockley BG, Bohnen NI, Albin RL, Scott PJH. Automated Synthesis of F-BCPP-EF {2--Butyl-4-Chloro-5-{6-[2-(2[F]fluoroethoxy)-Ethoxy]-Pyridin-3-ylmethoxy}-2-Pyridazin-3-One for Imaging of Mitochondrial Complex 1 in Parkinson's Disease. Frontiers in Chemistry. 10: 878835. PMID 35433631 DOI: 10.3389/fchem.2022.878835  0.361
2022 Bdair H, Singleton TA, Ross K, Jolly D, Kang MS, Aliaga A, Tuznik M, Kaur T, Yous S, Soucy JP, Massarweh G, Scott PJH, Koeppe R, Spadoni G, Bedini A, ... ... Brooks AF, et al. Radiosynthesis and Evaluation of Four Positron Emission Tomography Tracer Candidates for Imaging of Melatonin Receptors. Acs Chemical Neuroscience. PMID 35420022 DOI: 10.1021/acschemneuro.1c00678  0.361
2022 Wong KK, Else T, Viglianti BL, Brooks AF, Frey KA, Raffel DM. PET imaging of metastatic paraganglioma using novel 3-[F]fluoro-para-hydroxyphenethylguanidine (3-[F]pHPG) radiotracer. European Journal of Nuclear Medicine and Molecular Imaging. PMID 35089374 DOI: 10.1007/s00259-021-05639-y  0.355
2021 Kaur T, Brooks AF, Lapsys A, Desmond TJ, Stauff J, Arteaga J, Winton WP, Scott PJH. Synthesis and Evaluation of a Fluorine-18 Radioligand for Imaging Huntingtin Aggregates by Positron Emission Tomographic Imaging. Frontiers in Neuroscience. 15: 766176. PMID 34924935 DOI: 10.3389/fnins.2021.766176  0.352
2021 Lee SJ, Morales-Colón MT, Brooks AF, Wright JS, Makaravage KJ, Scott PJH, Sanford MS. SAr Radiofluorination with In Situ Generated [F]Tetramethylammonium Fluoride. The Journal of Organic Chemistry. PMID 34505779 DOI: 10.1021/acs.joc.1c01491  0.331
2021 Wright JS, Sharninghausen LS, Preshlock S, Brooks AF, Sanford MS, Scott PJH. Sequential Ir/Cu-Mediated Method for the -Selective C-H Radiofluorination of (Hetero)Arenes. Journal of the American Chemical Society. PMID 33914521 DOI: 10.1021/jacs.1c00523  0.309
2020 Wright JS, Kaur T, Preshlock S, Tanzey SS, Winton WP, Sharninghausen LS, Wiesner N, Brooks AF, Sanford MS, Scott PJH. Copper-Mediated Late-stage Radiofluorination: Five Years of Impact on Pre-clinical and Clinical PET Imaging. Clinical and Translational Imaging. 8: 167-206. PMID 33748018 DOI: 10.1007/S40336-020-00368-Y  0.428
2020 Zhao AY, Brooks AF, Raffel DM, Stauff J, Arteaga J, Scott PJH, Shao X. Fully Automated Radiosynthesis of [C]Guanidines for Cardiac PET Imaging. Acs Medicinal Chemistry Letters. 11: 2325-2330. PMID 33214848 DOI: 10.1021/acsmedchemlett.0c00479  0.331
2020 Brooks AF, Mufarreh AJ, Shao X, Kaur T, Stauff J, Arteaga J, Kilbourn MR, Scott PJH. Improved Synthesis of [C]COU and [C]PHXY, Evaluation of Neurotoxicity, and Imaging of MAOs in Rodent Heart. Acs Medicinal Chemistry Letters. 11: 2300-2304. PMID 33214844 DOI: 10.1021/Acsmedchemlett.0C00419  0.363
2020 Drake LR, Brooks AF, Stauff J, Sherman PS, Arteaga J, Koeppe RA, Reed A, Montavon TJ, Skaddan MB, Scott PJH. Strategies for PET imaging of the receptor for advanced glycation endproducts (RAGE). Journal of Pharmaceutical Analysis. 10: 452-465. PMID 33133729 DOI: 10.1016/J.Jpha.2020.07.009  0.406
2020 Tanzey SS, Mossine AV, Sowa AR, Torres J, Brooks AF, Sanford MS, Scott PJH. A spot test for determination of residual TBA levels in F-radiotracers for human use using Dragendorff reagent. Analytical Methods : Advancing Methods and Applications. PMID 33000785 DOI: 10.1039/d0ay01565b  0.357
2020 Murrell E, Pham JM, Sowa AR, Brooks AF, Kilbourn MR, Scott PJH, Vasdev N. Classics in Neuroimaging: Development of Positron Emission Tomography Tracers for Imaging the GABAergic Pathway. Acs Chemical Neuroscience. PMID 32578977 DOI: 10.1021/Acschemneuro.0C00343  0.324
2020 Hill JR, Shao X, Wright JS, Stauff J, Sherman PS, Arteaga J, Wong KK, Viglianti BL, Scott PJH, Brooks AF. Synthesis and Evaluation of C- and F-Labeled SOAT1 Inhibitors as Macrophage Foam Cell Imaging Agents. Acs Medicinal Chemistry Letters. 11: 1299-1304. PMID 32551015 DOI: 10.1021/Acsmedchemlett.0C00127  0.357
2020 Mossine AV, Tanzey SS, Brooks AF, Makaravage KJ, Ichiishi N, Miller JM, Henderson BD, Erhard T, Bruetting C, Skaddan MB, Sanford MS, Scott PJH. Synthesis of high-molar-activity [F]6-fluoro-L-DOPA suitable for human use via Cu-mediated fluorination of a BPin precursor. Nature Protocols. PMID 32269382 DOI: 10.1038/S41596-020-0305-9  0.461
2020 Sharninghausen LS, Brooks AF, Winton W, Makaravage KJ, Scott PJH, Sanford MS. NHC-Copper Mediated Ligand-Directed Radiofluorination of Aryl Halides. Journal of the American Chemical Society. PMID 32250612 DOI: 10.1021/Jacs.0C02637  0.439
2020 Kramer V, Brooks AF, Haeger A, Kuljs RO, Rafique W, Koeppe RA, Raffel DM, Frey KA, Amaral H, Scott PJH, Riss PJ. Evaluation of [F]N-methyl-lansoprazole as a tau PET imaging agent in first-in-human studies. Acs Chemical Neuroscience. PMID 31898886 DOI: 10.1021/Acschemneuro.9B00639  0.459
2019 Thompson S, Lee SJ, Jackson IM, Ichiishi N, Brooks AF, Sanford MS, Scott PJH. Synthesis of [F]-γ-fluoro-α,β,-unsaturated esters and ketones via vinylogous F-fluorination of α-diazoacetates with [F]AgF. Synthesis. 51: 4401-4407. PMID 32612311 DOI: 10.1055/S-0039-1690012  0.381
2019 Mossine AV, Tanzey SS, Brooks AF, Makaravage KJ, Ichiishi N, Miller JM, Henderson BD, Skaddan MB, Sanford MS, Scott PJH. One-pot synthesis of high molar activity 6-[F]fluoro-l-DOPA by Cu-mediated fluorination of a BPin precursor. Organic & Biomolecular Chemistry. PMID 31536095 DOI: 10.1039/C9Ob01758E  0.404
2019 Drake LR, Pham JM, Desmond TJ, Mossine AV, Lee SJ, Kilbourn MR, Koeppe RA, Brooks AF, Scott PJH. Identification of AV-1451 as a Weak, Nonselective Inhibitor of Monoamine Oxidase. Acs Chemical Neuroscience. PMID 31339297 DOI: 10.1021/Acschemneuro.9B00326  0.444
2019 Verhoog S, Brooks AF, Winton WP, Viglianti BL, Sanford MS, Scott PJH. Ring opening of epoxides with [F]FeF species to produce [F]fluorohydrin PET imaging agents. Chemical Communications (Cambridge, England). PMID 31062010 DOI: 10.1039/C9Cc02779C  0.454
2019 Narayanaswami V, Drake LR, Brooks AF, Meyer JH, Houle S, Kilbourn MR, Scott PJH, Vasdev N. Classics in Neuroimaging: Development of PET Tracers for Imaging Monoamine Oxidases. Acs Chemical Neuroscience. PMID 30789704 DOI: 10.1021/Acschemneuro.9B00081  0.376
2019 Lee SJ, Brooks AF, Ichiishi N, Makaravage KJ, Mossine AV, Sanford MS, Scott PJH. C-H F-fluorination of 8-methylquinolines with Ag[F]F. Chemical Communications (Cambridge, England). PMID 30778496 DOI: 10.1039/C9Cc00641A  0.423
2019 Lee SJ, Makaravage KJ, Brooks AF, Scott P, Sanford MS. Cu-Mediated Aminoquinoline-Directed Radiofluorination of Aromatic C-H Bonds with K¹⁸F. Angewandte Chemie (International Ed. in English). PMID 30605563 DOI: 10.1002/Anie.201812701  0.309
2018 Yang L, Brooks AF, Makaravage KJ, Zhang H, Sanford MS, Scott PJH, Shao X. Radiosynthesis of [C]LY2795050 for Preclinical and Clinical PET Imaging Using Cu(II)-Mediated Cyanation. Acs Medicinal Chemistry Letters. 9: 1274-1279. PMID 30613339 DOI: 10.1021/Acsmedchemlett.8B00460  0.409
2018 Brooks AF, Drake LR, Shao X, Zhao A, Scott PJH, Kilbourn MR. Evaluation of Enzyme Substrate Radiotracers as PET/MRS Hybrid Imaging Agents. Acs Medicinal Chemistry Letters. 9: 1140-1143. PMID 30429959 DOI: 10.1021/Acsmedchemlett.8B00402  0.38
2018 Drake LR, Brooks AF, Mufarreh AJ, Pham JM, Koeppe RA, Shao X, Scott PJH, Kilbourn MR. Deuterium Kinetic Isotope Effect Studies of a Potential In Vivo Metabolic Trapping Agent for Monoamine Oxidase-B. Acs Chemical Neuroscience. PMID 30074755 DOI: 10.1021/Acschemneuro.8B00219  0.363
2018 Sowa AR, Brooks AF, Shao X, Henderson BD, Sherman PS, Arteaga J, Stauff J, Lee AC, Koeppe RA, Scott PJH, Kilbourn MR. Development of Positron Emission Tomography (PET) Radiotracers for the GABA Transporter 1 (GAT-1). Acs Chemical Neuroscience. PMID 29763549 DOI: 10.1021/Acschemneuro.8B00183  0.417
2018 Makaravage KJ, Shao X, Brooks AF, Yang L, Sanford MS, Scott PJH. Copper(II)-Mediated [C]Cyanation of Arylboronic Acids and Arylstannanes. Organic Letters. PMID 29484880 DOI: 10.1021/Acs.Orglett.8B00242  0.332
2017 Mossine AV, Brooks AF, Henderson BD, Hockley BG, Frey KA, Scott PJH. An updated radiosynthesis of [F]AV1451 for tau PET imaging. Ejnmmi Radiopharmacy and Chemistry. 2: 7. PMID 29503848 DOI: 10.1186/S41181-017-0027-7  0.435
2017 Xing J, Brooks AF, Fink D, Zhang H, Piert MR, Scott PJH, Shao X. High-Yielding Automated Convergent Synthesis of No-Carrier-Added [11C-Carbonyl]-Labeled Amino Acids Using the Strecker Reaction. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 28: 371-375. PMID 29430080 DOI: 10.1055/S-0036-1588638  0.356
2017 Mossine AV, Brooks AF, Bernard-Gauthier V, Bailey JJ, Ichiishi N, Schirrmacher R, Sanford MS, Scott PJH. Automated Synthesis of PET Radiotracers by Copper-mediated (18) F-Fluorination of Organoborons: Importance of the Order of Addition and Competing Protodeborylation. Journal of Labelled Compounds & Radiopharmaceuticals. PMID 29143408 DOI: 10.1002/Jlcr.3583  0.431
2017 McCammant MS, Thompson S, Brooks AF, Krska SW, Scott PJH, Sanford MS. Cu-Mediated C-H (18)F-Fluorination of Electron-Rich (Hetero)arenes. Organic Letters. PMID 28665619 DOI: 10.1021/Acs.Orglett.7B01902  0.394
2017 Mossine AV, Brooks AF, Ichiishi N, Makaravage KJ, Sanford MS, Scott PJ. Development of Customized [(18)F]Fluoride Elution Techniques for the Enhancement of Copper-Mediated Late-Stage Radiofluorination. Scientific Reports. 7: 233. PMID 28331174 DOI: 10.1038/S41598-017-00110-1  0.376
2016 Makaravage KJ, Brooks AF, Mossine AV, Sanford MS, Scott PJ. Copper-Mediated Radiofluorination of Arylstannanes with [(18)F]KF. Organic Letters. PMID 27718581 DOI: 10.1021/Acs.Orglett.6B02911  0.431
2016 Mossine AV, Thompson S, Brooks AF, Sowa AR, Miller JM, Scott PJ. Fluorine-18 patents (2009-2015). Part 2: new radiochemistry. Pharmaceutical Patent Analyst. 5: 319-349. PMID 27610753 DOI: 10.4155/Ppa-2016-0028  0.413
2016 Mossine AV, Brooks AF, Jackson IM, Quesada CA, Sherman PS, Cole EL, Donnelly D, Scott PJ, Shao X. Synthesis of Diverse (11)C-Labelled PET Radiotracers via Direct Incorporation of [(11)C]CO 2. Bioconjugate Chemistry. PMID 27043721 DOI: 10.1021/Acs.Bioconjchem.6B00163  0.364
2016 Cary BP, Brooks AF, Fawaz MV, Drake LR, Desmond TJ, Sherman P, Quesada CA, Scott PJ. Synthesis and Evaluation of [(18)F]RAGER: A First Generation Small-Molecule PET Radioligand Targeting the Receptor for Advanced Glycation Endproducts. Acs Chemical Neuroscience. PMID 26771209 DOI: 10.1021/Acschemneuro.5B00319  0.442
2016 Brooks AF, Drake LR, Stewart MN, Cary BP, Jackson IM, Mallette D, Mossine AV, Scott PJ. Fluorine-18 patents (2009-2015). Part 1: novel radiotracers. Pharmaceutical Patent Analyst. 5: 17-47. PMID 26670619 DOI: 10.4155/Ppa.15.36  0.437
2015 Mossine AV, Brooks AF, Makaravage KJ, Miller JM, Ichiishi N, Sanford MS, Scott PJ. Synthesis of [(18)F]Arenes via the Copper-Mediated [(18)F]Fluorination of Boronic Acids. Organic Letters. PMID 26568457 DOI: 10.1021/Acs.Orglett.5B02875  0.425
2015 Brooks AF, Shao X, Quesada CA, Sherman P, Scott PJ, Kilbourn MR. In Vivo Metabolic Trapping Radiotracers for Imaging Monoamine Oxidase-A and -B Enzymatic Activity. Acs Chemical Neuroscience. PMID 26393369 DOI: 10.1021/Acschemneuro.5B00223  0.326
2015 Brooks AF, Jackson IM, Shao X, Kropog GW, Sherman P, Quesada CA, Scott PJ. Synthesis and evaluation of [(11)C]PBD150, a radiolabeled glutaminyl cyclase inhibitor for the potential detection of Alzheimer's disease prior to amyloid β aggregation. Medchemcomm. 6: 1065-1068. PMID 26101580 DOI: 10.1039/C5Md00148J  0.358
2015 Cary BP, Brooks AF, Fawaz MV, Shao X, Desmond TJ, Carpenter GM, Sherman P, Quesada CA, Albin RL, Scott PJ. Targeting Metal-Aβ Aggregates with Bifunctional Radioligand [(11)C]L2-b and a Fluorine-18 Analogue [(18)F]FL2-b. Acs Medicinal Chemistry Letters. 6: 112-116. PMID 25705326 DOI: 10.1021/Ml500413D  0.334
2014 Brooks AF, Topczewski JJ, Ichiishi N, Sanford MS, Scott PJ. Late-stage [(18)F]Fluorination: New Solutions to Old Problems. Chemical Science (Royal Society of Chemistry : 2010). 5: 4545-4553. PMID 25379166 DOI: 10.1039/C4Sc02099E  0.341
2014 Fawaz MV, Brooks AF, Rodnick ME, Carpenter GM, Shao X, Desmond TJ, Sherman P, Quesada CA, Hockley BG, Kilbourn MR, Albin RL, Frey KA, Scott PJ. High affinity radiopharmaceuticals based upon lansoprazole for PET imaging of aggregated tau in Alzheimer's disease and progressive supranuclear palsy: synthesis, preclinical evaluation, and lead selection. Acs Chemical Neuroscience. 5: 718-30. PMID 24896980 DOI: 10.1021/Cn500103U  0.42
2014 Ichiishi N, Brooks AF, Topczewski JJ, Rodnick ME, Sanford MS, Scott PJ. Copper-catalyzed [18F]fluorination of (mesityl)(aryl)iodonium salts. Organic Letters. 16: 3224-7. PMID 24890658 DOI: 10.1021/Ol501243G  0.429
2013 Rodnick ME, Brooks AF, Hockley BG, Henderson BD, Scott PJ. A fully-automated one-pot synthesis of [18F]fluoromethylcholine with reduced dimethylaminoethanol contamination via [18F]fluoromethyl tosylate. Applied Radiation and Isotopes : Including Data, Instrumentation and Methods For Use in Agriculture, Industry and Medicine. 78: 26-32. PMID 23665261 DOI: 10.1016/J.Apradiso.2013.04.017  0.41
2012 Shao X, Carpenter GM, Desmond TJ, Sherman P, Quesada CA, Fawaz M, Brooks AF, Kilbourn MR, Albin RL, Frey KA, Scott PJ. Evaluation of [(11)C]N-Methyl Lansoprazole as a Radiopharmaceutical for PET Imaging of Tau Neurofibrillary Tangles. Acs Medicinal Chemistry Letters. 3: 936-41. PMID 24900410 DOI: 10.1021/Ml300216T  0.363
2012 Brooks AF, Vélez-Martínez CS, Showalter HD, Garcia GA. Investigating the prevalence of queuine in Escherichia coli RNA via incorporation of the tritium-labeled precursor, preQ(1). Biochemical and Biophysical Research Communications. 425: 83-8. PMID 22819844 DOI: 10.1016/J.Bbrc.2012.07.055  0.519
2011 Chen YC, Brooks AF, Goodenough-Lashua DM, Kittendorf JD, Showalter HD, Garcia GA. Evolution of eukaryal tRNA-guanine transglycosylase: insight gained from the heterocyclic substrate recognition by the wild-type and mutant human and Escherichia coli tRNA-guanine transglycosylases. Nucleic Acids Research. 39: 2834-44. PMID 21131277 DOI: 10.1093/Nar/Gkq1188  0.524
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