Louis Premkumar, PhD - Publications

Affiliations: 
Pharmacology SIU School Medicine 
Area:
ion channels, receptors

60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Khare P, Jagtap S, Jain Y, Baboota RK, Mangal P, Boparai RK, Bhutani KK, Sharma SS, Premkumar LS, Kondepudi KK, Chopra K, Bishnoi M. Cinnamaldehyde supplementation prevents fasting-induced hyperphagia, lipid accumulation, and inflammation in high-fat diet-fed mice. Biofactors (Oxford, England). PMID 26893251 DOI: 10.1002/biof.1265  1
2015 Bishnoi M, Khare P, Kondepudi KK, Premkumar LS. The Role of TRPV1 in Acquired Diseases: Therapeutic Potential of TRPV1 Modulators. Therapeutic Potential of TRPV1 Modulators Trp Channels as Therapeutic Targets: From Basic Science to Clinical Use. 35-58. DOI: 10.1016/B978-0-12-420024-1.00003-5  1
2015 Yu SQ, Premkumar LS. Ablation and regeneration of peripheral and central trpv1 expressing nerve terminals and the consequence of nociception Open Pain Journal. 8: 1-9.  1
2014 Premkumar LS. Transient receptor potential channels as targets for phytochemicals. Acs Chemical Neuroscience. 5: 1117-30. PMID 24926802 DOI: 10.1021/cn500094a  1
2014 Baboota RK, Murtaza N, Jagtap S, Singh DP, Karmase A, Kaur J, Bhutani KK, Boparai RK, Premkumar LS, Kondepudi KK, Bishnoi M. Capsaicin-induced transcriptional changes in hypothalamus and alterations in gut microbial count in high fat diet fed mice. The Journal of Nutritional Biochemistry. 25: 893-902. PMID 24917046 DOI: 10.1016/j.jnutbio.2014.04.004  1
2013 Premkumar LS, Pabbidi RM. Diabetic peripheral neuropathy: role of reactive oxygen and nitrogen species. Cell Biochemistry and Biophysics. 67: 373-83. PMID 23722999 DOI: 10.1007/s12013-013-9609-5  1
2013 Premkumar LS, Abooj M. TRP channels and analgesia. Life Sciences. 92: 415-24. PMID 22910182 DOI: 10.1016/j.lfs.2012.08.010  1
2013 Bishnoi M, Premkumar LS. Changes in TRP channels expression in painful conditions Open Pain Journal. 6: 10-22. DOI: 10.2174/1876386301306010010  1
2012 Cao DS, Zhong L, Hsieh TH, Abooj M, Bishnoi M, Hughes L, Premkumar LS. Expression of transient receptor potential ankyrin 1 (TRPA1) and its role in insulin release from rat pancreatic beta cells. Plos One. 7: e38005. PMID 22701540 DOI: 10.1371/journal.pone.0038005  1
2012 Evans MS, Cheng X, Jeffry JA, Disney KE, Premkumar LS. Sumatriptan inhibits TRPV1 channels in trigeminal neurons. Headache. 52: 773-84. PMID 22289052 DOI: 10.1111/j.1526-4610.2011.02053.x  1
2012 Walia V, Yu Y, Cao D, Sun M, McLean JR, Hollier BG, Cheng J, Mani SA, Rao K, Premkumar L, Elble RC. Loss of breast epithelial marker hCLCA2 promotes epithelial-to-mesenchymal transition and indicates higher risk of metastasis. Oncogene. 31: 2237-46. PMID 21909135 DOI: 10.1038/onc.2011.392  1
2011 Bishnoi M, Bosgraaf CA, Abooj M, Zhong L, Premkumar LS. Streptozotocin-induced early thermal hyperalgesia is independent of glycemic state of rats: role of transient receptor potential vanilloid 1(TRPV1) and inflammatory mediators. Molecular Pain. 7: 52. PMID 21794120 DOI: 10.1186/1744-8069-7-52  1
2011 Bishnoi M, Bosgraaf CA, Premkumar LS. Preservation of acute pain and efferent functions following intrathecal resiniferatoxin-induced analgesia in rats. The Journal of Pain : Official Journal of the American Pain Society. 12: 991-1003. PMID 21680254 DOI: 10.1016/j.jpain.2011.03.005  1
2011 Premkumar LS, Bishnoi M. Disease-related changes in TRPV1 expression and its implications for drug development. Current Topics in Medicinal Chemistry. 11: 2192-209. PMID 21671875 DOI: 10.2174/156802611796904834  1
2011 Raisinghani M, Zhong L, Jeffry JA, Bishnoi M, Pabbidi RM, Pimentel F, Cao DS, Evans MS, Premkumar LS. Activation characteristics of transient receptor potential ankyrin 1 and its role in nociception. American Journal of Physiology. Cell Physiology. 301: C587-600. PMID 21653898 DOI: 10.1152/ajpcell.00465.2010  1
2011 Lee RH, Liu YQ, Chen PY, Liu CH, Chen MF, Lin HW, Kuo JS, Premkumar LS, Lee TJ. Sympathetic α₃β₂-nAChRs mediate cerebral neurogenic nitrergic vasodilation in the swine. American Journal of Physiology. Heart and Circulatory Physiology. 301: H344-54. PMID 21536845 DOI: 10.1152/ajpheart.00172.2011  1
2011 Samineni VK, Premkumar LS, Faingold CL. Post-ictal analgesia in genetically epilepsy-prone rats is induced by audiogenic seizures and involves cannabinoid receptors in the periaqueductal gray. Brain Research. 1389: 177-82. PMID 21439272 DOI: 10.1016/j.brainres.2011.03.041  1
2011 Liu G, Hu X, Premkumar L, Chakrabarty S. Nifedipine synergizes with calcium in activating the calcium sensing receptor, suppressing the expression of thymidylate synthase and survivin and promoting sensitivity to fluorouracil in human colon carcinoma cells. Molecular Carcinogenesis. 50: 922-30. PMID 21374737 DOI: 10.1002/mc.20752  1
2011 Bishnoi M, Premkumar LS. Possible consequences of blocking transient receptor potential vanilloid. Current Pharmaceutical Biotechnology. 12: 102-14. PMID 20932252 DOI: 10.2174/138920111793937907  1
2010 Premkumar LS. Targeting TRPV1 as an alternative approach to narcotic analgesics to treat chronic pain conditions. The Aaps Journal. 12: 361-70. PMID 20440589 DOI: 10.1208/s12248-010-9196-y  1
2009 Jeffry JA, Yu SQ, Sikand P, Parihar A, Evans MS, Premkumar LS. Selective targeting of TRPV1 expressing sensory nerve terminals in the spinal cord for long lasting analgesia. Plos One. 4: e7021. PMID 19753113 DOI: 10.1371/journal.pone.0007021  1
2009 Walia V, Ding M, Kumar S, Nie D, Premkumar LS, Elble RC. hCLCA2 Is a p53-Inducible Inhibitor of Breast Cancer Cell Proliferation. Cancer Research. 69: 6624-32. PMID 19654313 DOI: 10.1158/0008-5472.CAN-08-4101  1
2009 Cao DS, Yu SQ, Premkumar LS. Modulation of transient receptor potential Vanilloid 4-mediated membrane currents and synaptic transmission by protein kinase C. Molecular Pain. 5: 5. PMID 19208258 DOI: 10.1186/1744-8069-5-5  1
2009 Hung WL, Liu CZ, Cao D, Chen PY, Chen MF, Lin SZ, Mozayan M, Chen AF, Premkumar LS, Torry DS, Lee TJF. Endogenous methyl palmitate modulates nicotinic receptor-mediated transmission in the superior cervical ganglion (Proceeding of the National Academy of Sciences of the United States of America (2008) 105, 49, (19526-19531) DOI: 10.1073/pnas.0810262105) Proceedings of the National Academy of Sciences of the United States of America. 106: 4060. DOI: 10.1073/pnas.0812542106  1
2008 Premkumar LS, Sikand P. TRPV1: a target for next generation analgesics. Current Neuropharmacology. 6: 151-63. PMID 19305794 DOI: 10.2174/157015908784533888  1
2008 Lin HW, Liu CZ, Cao D, Chen PY, Chen MF, Lin SZ, Mozayan M, Chen AF, Premkumar LS, Torry DS, Lee TJ. Endogenous methyl palmitate modulates nicotinic receptor-mediated transmission in the superior cervical ganglion. Proceedings of the National Academy of Sciences of the United States of America. 105: 19526-31. PMID 19057014 DOI: 10.1073/pnas.0810262105  1
2008 Pabbidi RM, Yu SQ, Peng S, Khardori R, Pauza ME, Premkumar LS. Influence of TRPV1 on diabetes-induced alterations in thermal pain sensitivity. Molecular Pain. 4: 9. PMID 18312687 DOI: 10.1186/1744-8069-4-9  1
2008 Pabbidi RM, Cao DS, Parihar A, Pauza ME, Premkumar LS. Direct role of streptozotocin in inducing thermal hyperalgesia by enhanced expression of transient receptor potential vanilloid 1 in sensory neurons. Molecular Pharmacology. 73: 995-1004. PMID 18089839 DOI: 10.1124/mol.107.041707  1
2007 Sikand P, Premkumar LS. Potentiation of glutamatergic synaptic transmission by protein kinase C-mediated sensitization of TRPV1 at the first sensory synapse. The Journal of Physiology. 581: 631-47. PMID 17363391 DOI: 10.1113/jphysiol.2006.118620  1
2006 Premkumar LS, Raisinghani M. Nociceptors in cardiovascular functions: complex interplay as a result of cyclooxygenase inhibition. Molecular Pain. 2: 26. PMID 16916451 DOI: 10.1186/1744-8069-2-26  1
2006 Mozayan M, Chen MF, Si M, Chen PY, Premkumar LS, Lee TJ. Cholinesterase inhibitor blockade and its prevention by statins of sympathetic alpha7-nAChR-mediated cerebral nitrergic neurogenic vasodilation. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 26: 1562-76. PMID 16639428 DOI: 10.1038/sj.jcbfm.9600310  1
2005 Premkumar LS, Raisinghani M, Pingle SC, Long C, Pimentel F. Downregulation of transient receptor potential melastatin 8 by protein kinase C-mediated dephosphorylation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 11322-9. PMID 16339027 DOI: 10.1523/JNEUROSCI.3006-05.2005  1
2005 Premkumar LS. Block of a Ca(2+)-activated potassium channel by cocaine. The Journal of Membrane Biology. 204: 129-36. PMID 16245035 DOI: 10.1007/s00232-005-0755-6  1
2005 Raisinghani M, Pabbidi RM, Premkumar LS. Activation of transient receptor potential vanilloid 1 (TRPV1) by resiniferatoxin. The Journal of Physiology. 567: 771-86. PMID 16037081 DOI: 10.1113/jphysiol.2005.087874  1
2005 Van Buren JJ, Bhat S, Rotello R, Pauza ME, Premkumar LS. Sensitization and translocation of TRPV1 by insulin and IGF-I. Molecular Pain. 1: 17. PMID 15857517 DOI: 10.1186/1744-8069-1-17  1
2005 Raisinghani M, Premkumar LS. Block of native and cloned vanilloid receptor 1 (TRPV1) by aminoglycoside antibiotics. Pain. 113: 123-33. PMID 15621372 DOI: 10.1016/j.pain.2004.09.042  1
2004 Puntambekar P, Van Buren J, Raisinghani M, Premkumar LS, Ramkumar V. Direct interaction of adenosine with the TRPV1 channel protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3663-71. PMID 15071115 DOI: 10.1523/JNEUROSCI.4773-03.2004  1
2004 Premkumar LS, Qi ZH, Van Buren J, Raisinghani M. Enhancement of potency and efficacy of NADA by PKC-mediated phosphorylation of vanilloid receptor. Journal of Neurophysiology. 91: 1442-9. PMID 14973326 DOI: 10.1152/jn.00745.2003  1
2002 Ahern GP, Premkumar LS. Voltage-dependent priming of rat vanilloid receptor: effects of agonist and protein kinase C activation. The Journal of Physiology. 545: 441-51. PMID 12456824 DOI: 10.1113/jphysiol.2002.029561  1
2002 Watanabe J, Beck C, Kuner T, Premkumar LS, Wollmuth LP. DRPEER: a motif in the extracellular vestibule conferring high Ca2+ flux rates in NMDA receptor channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 10209-16. PMID 12451122  1
2002 Premkumar LS, Agarwal S, Steffen D. Single-channel properties of native and cloned rat vanilloid receptors. The Journal of Physiology. 545: 107-17. PMID 12433953 DOI: 10.1113/jphysiol.2002.016352  1
2002 Sasaki YF, Rothe T, Premkumar LS, Das S, Cui J, Talantova MV, Wong HK, Gong X, Chan SF, Zhang D, Nakanishi N, Sucher NJ, Lipton SA. Characterization and comparison of the NR3A subunit of the NMDA receptor in recombinant systems and primary cortical neurons. Journal of Neurophysiology. 87: 2052-63. PMID 11929923 DOI: 10.1152/jn.00531.2001  1
2002 Chatterton JE, Awobuluyi M, Premkumar LS, Takahashi H, Talantova M, Shin Y, Cui J, Tu S, Sevarino KA, Nakanishi N, Tong G, Lipton SA, Zhang D. Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits. Nature. 415: 793-8. PMID 11823786 DOI: 10.1038/nature715  1
2001 Premkumar LS. Interaction between vanilloid receptors and purinergic metabotropic receptors: pain perception and beyond. Proceedings of the National Academy of Sciences of the United States of America. 98: 6537-9. PMID 11390988 DOI: 10.1073/pnas.121190798  1
2000 Premkumar LS, Ahern GP. Induction of vanilloid receptor channel activity by protein kinase C. Nature. 408: 985-90. PMID 11140687 DOI: 10.1038/35050121  1
2000 Kuehl-Kovarik MC, Magnusson KR, Premkumar LS, Partin KM. Electrophysiological analysis of NMDA receptor subunit changes in the aging mouse cortex. Mechanisms of Ageing and Development. 115: 39-59. PMID 10854628 DOI: 10.1016/S0047-6374(00)00104-4  1
1999 Premkumar LS. Selective potentiation of L-type calcium channel currents by cocaine in cardiac myocytes. Molecular Pharmacology. 56: 1138-42. PMID 10570040  1
1998 Das S, Sasaki YF, Rothe T, Premkumar LS, Takasu M, Crandall JE, Dikkes P, Conner DA, Rayudu PV, Cheung W, Chen HS, Lipton SA, Nakanishi N. Increased NMDA current and spine density in mice lacking the NMDA receptor subunit NR3A. Nature. 393: 377-81. PMID 9620802 DOI: 10.1038/30748  1
1997 Premkumar LS, Auerbach A. Stoichiometry of recombinant N-methyl-D-aspartate receptor channels inferred from single-channel current patterns. The Journal of General Physiology. 110: 485-502. PMID 9348322 DOI: 10.1085/jgp.110.5.485  1
1997 Premkumar LS, Qin F, Auerbach A. Subconductance states of a mutant NMDA receptor channel kinetics, calcium, and voltage dependence. The Journal of General Physiology. 109: 181-9. PMID 9041447 DOI: 10.1085/jgp.109.2.181  1
1996 Sunstrom NA, Premkumar LS, Premkumar A, Ewart G, Cox GB, Gage PW. Ion channels formed by NB, an influenza B virus protein. The Journal of Membrane Biology. 150: 127-32. PMID 8661776 DOI: 10.1007/s002329900037  1
1996 Premkumar LS, Auerbach A. Identification of a high affinity divalent cation binding site near the entrance of the NMDA receptor channel. Neuron. 16: 869-80. PMID 8608005 DOI: 10.1016/S0896-6273(00)80107-5  1
1995 Premkumar LS, Ahern GP. Blockade of a resting potassium channel and modulation of synaptic transmission by ecstasy in the hippocampus. The Journal of Pharmacology and Experimental Therapeutics. 274: 718-22. PMID 7636733  1
1995 Premkumar L, Chung SH. Activation of K+ channels by stimulation of metabotropic glutamate receptors. Neuroreport. 6: 765-8. PMID 7605944  1
1994 Premkumar LS, Gage PW. Potassium channels activated by GABAB agonists and serotonin in cultured hippocampal neurons. Journal of Neurophysiology. 71: 2570-5. PMID 7931538  1
1993 Curmi JP, Premkumar LS, Birnir B, Gage PW. The influence of membrane potential on chloride channels activated by GABA in rat cultured hippocampal neurons. The Journal of Membrane Biology. 136: 273-80. PMID 8114077 DOI: 10.1007/BF00233666  1
1992 Vasudevan S, Premkumar L, Stowe S, Gage PW, Reiländer H, Chung SH. Muscarinic acetylcholine receptor produced in recombinant baculovirus infected Sf9 insect cells couples with endogenous G-proteins to activate ion channels. Febs Letters. 311: 7-11. PMID 1397295 DOI: 10.1016/0014-5793(92)81354-O  1
1990 Premkumar LS, Gage PW, Chung SH. Coupled potassium channels induced by arachidonic acid in cultured neurons. Proceedings. Biological Sciences / the Royal Society. 242: 17-22. PMID 1980738 DOI: 10.1098/rspb.1990.0097  1
1990 Premkumar LS, Chung SH, Gage PW. GABA-induced potassium channels in cultured neurons. Proceedings. Biological Sciences / the Royal Society. 241: 153-8. PMID 1978342 DOI: 10.1098/rspb.1990.0079  1
1990 Chung SH, Moore JB, Xia LG, Premkumar LS, Gage PW. Characterization of single channel currents using digital signal processing techniques based on Hidden Markov Models. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 329: 265-85. PMID 1702543 DOI: 10.1098/rstb.1990.0170  1
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