Jang-Ho J. Cha - Publications

2015- Neurosciences Novartis Institutes for BioMedical Research, Cambridge, MA, United States 
Huntington's disease, drug discovery

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Year Citation  Score
2016 Moon JH, Lee W, Park J, Choi KH, Cha J. Characterization of a trehalose-degrading enzyme from the hyperthermophilic archaeon Sulfolobus acidocaldarius. Journal of Bioscience and Bioengineering. PMID 26811220 DOI: 10.1016/j.jbiosc.2015.12.011  0.64
2016 Bae T, Ko J, Lee S, Cha J, Hong J. Co2MnSi Heusler alloy as an enhancing layer of perpendicular magnetic anisotropy for MgO-based magnetic tunnel junctions with L10 ordered FePd Japanese Journal of Applied Physics. 55. DOI: 10.7567/JJAP.55.013001  0.44
2015 Choi JC, Kim J, Kang E, Choi JH, Park WY, Choi YS, Cha J, Han C, Park SK, Kim MH, Lee GH, Do HJ, Jung SW, Lee JM. Step-down vs. step-up noxious stimulation: differential effects on pain perception and patterns of brain activation. Acta Anaesthesiologica Scandinavica. PMID 26355384 DOI: 10.1111/aas.12607  0.76
2015 Kim JS, Yoon BY, Ahn J, Cha J, Ha NC. Crystal structure of β-N-acetylglucosaminidase CbsA from Thermotoga neapolitana. Biochemical and Biophysical Research Communications. PMID 26187666 DOI: 10.1016/j.bbrc.2015.07.053  0.56
2015 Ham JH, Cha J, Lee JJ, Baek GM, Sunwoo MK, Hong JY, Shin NY, Sohn YH, Lee JM, Lee PH. Nigrostriatal dopamine-independent resting-state functional networks in Parkinson's disease. Neuroimage. PMID 26143204 DOI: 10.1016/j.neuroimage.2015.06.077  0.6
2015 Bang OY, Ryoo S, Kim SJ, Yoon CH, Cha J, Yeon JY, Kim KH, Kim GM, Chung CS, Lee KH, Shin HJ, Ki CS, Jeon P, Kim JS, Hong SC. Adult Moyamoya Disease: A Burden of Intracranial Stenosis in East Asians? Plos One. 10: e0130663. PMID 26125557 DOI: 10.1371/journal.pone.0130663  0.76
2015 Jeong YH, Lee CK, Jo K, Hwang SH, Cha J, Lee JW, Yun M, Cho A. Correlation Analysis and Prognostic Impact of (18)F-FDG PET and Excision Repair Cross-Complementation Group 1 (ERCC-1) Expression in Non-Small Cell Lung Cancer. Nuclear Medicine and Molecular Imaging. 49: 108-14. PMID 26085855 DOI: 10.1007/s13139-014-0304-2  0.36
2015 Oh S, Cha J, Ji M, Kang H, Kim S, Heo E, Han JS, Kang H, Chae H, Hwang H, Yoo S. Architecture Design of Healthcare Software-as-a-Service Platform for Cloud-Based Clinical Decision Support Service. Healthcare Informatics Research. 21: 102-10. PMID 25995962 DOI: 10.4258/hir.2015.21.2.102  0.72
2015 Cha J, Burnum-Johnson KE, Bartos A, Li Y, Baker ES, Tilton SC, Webb-Robertson BJ, Piehowski PD, Monroe ME, Jegga AG, Murata S, Hirota Y, Dey SK. Muscle Segment Homeobox Genes Direct Embryonic Diapause by Limiting Inflammation in the Uterus. The Journal of Biological Chemistry. 290: 15337-49. PMID 25931120 DOI: 10.1074/jbc.M115.655001  0.36
2015 Liu Y, Liu J, Sohn S, Li Y, Cha JJ, Schroers J. Metallic glass nanostructures of tunable shape and composition. Nature Communications. 6: 7043. PMID 25901951 DOI: 10.1038/ncomms8043  0.32
2015 Choi JC, Kim J, Kang E, Lee JM, Cha J, Kim YJ, Lee HG, Choi JH, Yi DJ. Brain mechanisms of pain relief by transcutaneous electrical nerve stimulation: A functional magnetic resonance imaging study. European Journal of Pain (London, England). PMID 25847717 DOI: 10.1002/ejp.696  0.76
2015 Kim JK, Won CI, Cha J, Lee K, Kim DS. Optimal ligand descriptor for pocket recognition based on the Beta-shape. Plos One. 10: e0122787. PMID 25835497 DOI: 10.1371/journal.pone.0122787  0.64
2015 Lee JM, Lee HC, Gwon SY, Jung D, Pan W, Cho CW, Park KR, Kim HC, Cha J. A new gaze estimation method considering external light. Sensors (Basel, Switzerland). 15: 5935-81. PMID 25769050 DOI: 10.3390/s150305935  0.76
2015 Cha J, Zhou M, Liu Y. Methods to study molecular mechanisms of the Neurospora circadian clock. Methods in Enzymology. 551: 137-51. PMID 25662455 DOI: 10.1016/bs.mie.2014.10.002  0.32
2015 Hwang S, Choi KH, Yoon N, Cha J. Improvement of a Sulfolobus-E. coli shuttle vector for heterologous gene expression in Sulfolobus acidocaldarius. Journal of Microbiology and Biotechnology. 25: 196-205. PMID 25293629 DOI: 10.4014/jmb.1407.07043  0.64
2015 Kan SY, Cha J, Chia PW. A case study on using uncritical inference test to promote Malaysian college students' deeper thinking in organic chemistry Journal of the Korean Chemical Society. 59: 156-163. DOI: 10.5012/jkcs.2015.59.2.156  0.72
2015 Yang SY, Naser N, Chung SH, Cha J. Effect of Temperature, Pressure and Equivalence Ratio on Ignition Delay in Ignition Quality Tester (IQT): Diesel, n-Heptane, and iso-Octane Fuels under Low Temperature Conditions Sae International Journal of Fuels and Lubricants. 8: 537-548. DOI: 10.4271/2015-01-9074  0.72
2015 Chu S, Lee J, Cha J, Choi H, Min K. An Experimental Investigation of Injection and Operating Strategies on Diesel Single Cylinder Engine under JP-8 and Dual-Fuel PCCI Combustion Sae Technical Papers. 2015. DOI: 10.4271/2015-01-0844  0.72
2015 Cha J, Jang EJ, Jung M, Kim Dy, Kim DH, Lee YK, Park S, Kim KS, Chung WS. On the exact solutions of the damped harmonic oscillator with a time-dependent damping constant and a time-dependent angular frequency Journal of the Korean Physical Society. 67: 404-408. DOI: 10.3938/jkps.67.404  0.6
2015 Park JW, Yoon J, Cha J, Lee HS. Determination of molecular weight distribution and composition dependence of monomeric friction factors from the stress relaxation of ultrahigh molecular weight polyethylene gels Journal of Rheology. 59: 1173-1189. DOI: 10.1122/1.4928072  0.36
2015 Cha J, Kang W, Chung J, Park K, Kang S. A New Accelerated Endurance Test for Terabit NAND Flash Memory Using Interference Effect Ieee Transactions On Semiconductor Manufacturing. 28: 399-407. DOI: 10.1109/TSM.2015.2429211  0.32
2015 Yun J, Kang G, Park Y, Moon S, Lim J, Cha JJ, Lee JH. Electrical impedance spectroscopy for biotissue differentiation using bipolar electrodes positioned at the end of a hypodermic needle 2015 Transducers - 2015 18th International Conference On Solid-State Sensors, Actuators and Microsystems, Transducers 2015. 1533-1536. DOI: 10.1109/TRANSDUCERS.2015.7181229  0.32
2015 Ju J, Han D, Kim J, Lee I, Cha J. A new control owner switching system for multiple TV viewers via face recognition 2015 Ieee International Conference On Consumer Electronics, Icce 2015. 323-326. DOI: 10.1109/ICCE.2015.7066431  0.76
2015 Lee I, Cha J, Seo J, Kwon O. User interest visualizing and analysing system using eye gaze International Conference On Advanced Communication Technology, Icact. 2015: 275-278. DOI: 10.1109/ICACT.2015.7224802  0.52
2015 Zhu X, Morales-Acosta MD, Shen J, Walker FJ, Cha JJ, Altman EI. Growth, structure, and electronic properties of nonpolar thin films on a polar substrate: Cr2 O3 on ZnO (0001) and ZnO (000 1¯) GROWTH, STRUCTURE, and ELECTRONIC PROPERTIES ... ZHU, MORALES-ACOSTA, SHEN, WALKER, CHA, and ALTMAN Physical Review B - Condensed Matter and Materials Physics. 92. DOI: 10.1103/PhysRevB.92.165414  0.32
2015 Li X, Deng B, Wang X, Chen S, Vaisman M, Karato SI, Pan G, Lee ML, Cha J, Wang H, Xia F. Synthesis of thin-film black phosphorus on a flexible substrate 2d Materials. 2. DOI: 10.1088/2053-1583/2/3/031002  0.72
2015 Cha J, Yang S, Carlson KH. Occurrence of β-lactam and polyether ionophore antibiotics in surface water, urban wastewater, and sediment Geosystem Engineering. 18: 140-150. DOI: 10.1080/12269328.2015.1010658  0.72
2015 Sohn S, Jung Y, Xie Y, Osuji C, Schroers J, Cha JJ. Nanoscale size effects in crystallization of metallic glass nanorods Nature Communications. 6. DOI: 10.1038/ncomms9157  0.32
2015 Cha J, Zhou M, Liu Y. Mechanism of the Neurospora circadian clock, a FREQUENCY-centric view Biochemistry. 54: 150-156. DOI: 10.1021/bi5005624  0.72
2015 Jun SA, Cha J. High-toned [il] in Korean: Phonetics, intonational phonology, and sound change Journal of Phonetics. DOI: 10.1016/j.wocn.2015.05.002  0.72
2015 Hamza A, Hafiz R, Khan MM, Cho Y, Cha J. Stabilization of panoramic videos from mobile multi-camera platforms Image and Vision Computing. 37: 20-30. DOI: 10.1016/j.imavis.2015.02.002  0.72
2015 Kim S, Koh Y, Cha J, Lee S. Effects of social media on firm value for U.S. restaurant companies International Journal of Hospitality Management. 49: 40-46. DOI: 10.1016/j.ijhm.2015.05.006  0.72
2015 Lee J, Chu S, Cha J, Choi H, Min K. Effect of the diesel injection strategy on the combustion and emissions of propane/diesel dual fuel premixed charge compression ignition engines Energy. 93: 1041-1052. DOI: 10.1016/j.energy.2015.09.032  0.52
2015 Saeed S, Hafiz R, Rasul A, Khan MM, Cho Y, Park U, Cha J. A unified panoramic stitching and multi-projector rendering scheme for immersive panoramic displays Displays. DOI: 10.1016/j.displa.2015.06.002  0.72
2015 Park J, Ko J, Cha J, Jeong S. Stirling-type pulse tube refrigerator (PTR) with cold compression: Cold compressor, colder expander Cryogenics. DOI: 10.1016/j.cryogenics.2015.08.001  0.68
2015 Chen X, Zhao P, Xiang R, Kim S, Cha J, Chiashi S, Maruyama S. Chemical vapor deposition growth of 5 mm hexagonal single-crystal graphene from ethanol Carbon. 94: 810-815. DOI: 10.1016/j.carbon.2015.07.045  0.32
2015 Ko S, Kang S, Cha J. Performance comparison of covariance-assignment state estimators with intermittent observations International Journal of Control, Automation and Systems. 13: 1391-1401. DOI: 10.1007/s12555-015-0004-4  0.36
2015 Oh WY, Cha J, Chang YK. Does Ownership Structure Matter? The Effects of Insider and Institutional Ownership on Corporate Social Responsibility Journal of Business Ethics. DOI: 10.1007/s10551-015-2914-8  0.36
2015 Choi KH, Cha J. Membrane-bound amylopullulanase is essential for starch metabolism of Sulfolobus acidocaldarius DSM639 Extremophiles. DOI: 10.1007/s00792-015-0766-x  0.64
2015 Cha J, Cho BR. Classical Statistical Inference Extended to Truncated Populations for Continuous Process Improvement: Test Statistics, P-values, and Confidence Intervals Quality and Reliability Engineering International. 31: 1807-1824. DOI: 10.1002/qre.1719  0.36
2014 Kim KH, Park YD, Park H, Moon KO, Ha KT, Baek NI, Park CS, Joo M, Cha J. Synthesis and biological evaluation of a novel baicalein glycoside as an anti-inflammatory agent. European Journal of Pharmacology. 744: 147-56. PMID 25446915 DOI: 10.1016/j.ejphar.2014.10.013  0.64
2014 McFarland KN, Huizenga MN, Darnell SB, Sangrey GR, Berezovska O, Cha JH, Outeiro TF, Sadri-Vakili G. MeCP2: a novel Huntingtin interactor. Human Molecular Genetics. 23: 1036-44. PMID 24105466 DOI: 10.1093/hmg/ddt499  0.92
2013 McFarland KN, Das S, Sun TT, Leyfer D, Kim MO, Xia E, Sangrey GR, Kuhn A, Luthi-Carter R, Clark TW, Sadri-Vakili G, Cha JH. Genome-wide increase in histone H2A ubiquitylation in a mouse model of Huntington's disease. Journal of Huntington's Disease. 2: 263-77. PMID 25062675 DOI: 10.3233/JHD-130066  0.92
2012 McFarland KN, Das S, Sun TT, Leyfer D, Xia E, Sangrey GR, Kuhn A, Luthi-Carter R, Clark TW, Sadri-Vakili G, Cha JH. Genome-wide histone acetylation is altered in a transgenic mouse model of Huntington's disease. Plos One. 7: e41423. PMID 22848491 DOI: 10.1371/journal.pone.0041423  0.92
2012 Schmidt HD, Sangrey GR, Darnell SB, Schassburger RL, Cha JH, Pierce RC, Sadri-Vakili G. Increased brain-derived neurotrophic factor (BDNF) expression in the ventral tegmental area during cocaine abstinence is associated with increased histone acetylation at BDNF exon I-containing promoters. Journal of Neurochemistry. 120: 202-9. PMID 22043863 DOI: 10.1111/j.1471-4159.2011.07571.x  0.92
2011 McFarland KN, Cha JH. Molecular biology of Huntington's disease. Handbook of Clinical Neurology. 100: 25-81. PMID 21496570 DOI: 10.1016/B978-0-444-52014-2.00003-3  0.72
2010 Sadri-Vakili G, Kumaresan V, Schmidt HD, Famous KR, Chawla P, Vassoler FM, Overland RP, Xia E, Bass CE, Terwilliger EF, Pierce RC, Cha JH. Cocaine-induced chromatin remodeling increases brain-derived neurotrophic factor transcription in the rat medial prefrontal cortex, which alters the reinforcing efficacy of cocaine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 11735-44. PMID 20810894 DOI: 10.1523/JNEUROSCI.2328-10.2010  0.92
2010 Benn CL, Luthi-Carter R, Kuhn A, Sadri-Vakili G, Blankson KL, Dalai SC, Goldstein DR, Spires TL, Pritchard J, Olson JM, van Dellen A, Hannan AJ, Cha JH. Environmental enrichment reduces neuronal intranuclear inclusion load but has no effect on messenger RNA expression in a mouse model of Huntington disease. Journal of Neuropathology and Experimental Neurology. 69: 817-27. PMID 20613636 DOI: 10.1097/NEN.0b013e3181ea167f  0.92
2009 Brocklebank D, Gayán J, Andresen JM, Roberts SA, Young AB, Snodgrass SR, Penney JB, Ramos-Arroyo MA, Cha JJ, Rosas HD, Hersch SM, Feigin A, Cherny SS, Wexler NS, Housman DE, et al. Repeat instability in the 27-39 CAG range of the HD gene in the Venezuelan kindreds: Counseling implications. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 150: 425-9. PMID 18712713 DOI: 10.1002/ajmg.b.30826  0.72
2008 Famous KR, Kumaresan V, Sadri-Vakili G, Schmidt HD, Mierke DF, Cha JH, Pierce RC. Phosphorylation-dependent trafficking of GluR2-containing AMPA receptors in the nucleus accumbens plays a critical role in the reinstatement of cocaine seeking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11061-70. PMID 18945913 DOI: 10.1523/JNEUROSCI.1221-08.2008  0.92
2008 Liu W, Kennington LA, Rosas HD, Hersch S, Cha JH, Zamore PD, Aronin N. Linking SNPs to CAG repeat length in Huntington's disease patients. Nature Methods. 5: 951-3. PMID 18931668 DOI: 10.1038/nmeth.1261  0.4
2008 Benn CL, Sun T, Sadri-Vakili G, McFarland KN, DiRocco DP, Yohrling GJ, Clark TW, Bouzou B, Cha JH. Huntingtin modulates transcription, occupies gene promoters in vivo, and binds directly to DNA in a polyglutamine-dependent manner. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10720-33. PMID 18923047 DOI: 10.1523/JNEUROSCI.2126-08.2008  0.92
2008 Broom WJ, Greenway M, Sadri-Vakili G, Russ C, Auwarter KE, Glajch KE, Dupre N, Swingler RJ, Purcell S, Hayward C, Sapp PC, McKenna-Yasek D, Valdmanis PN, Bouchard JP, Meininger V, ... ... Cha JH, et al. 50bp deletion in the promoter for superoxide dismutase 1 (SOD1) reduces SOD1 expression in vitro and may correlate with increased age of onset of sporadic amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 9: 229-37. PMID 18608091 DOI: 10.1080/17482960802103107  0.4
2008 Kim MO, Chawla P, Overland RP, Xia E, Sadri-Vakili G, Cha JH. Altered histone monoubiquitylation mediated by mutant huntingtin induces transcriptional dysregulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 3947-57. PMID 18400894 DOI: 10.1523/JNEUROSCI.5667-07.2008  0.92
2008 Anderson SM, Famous KR, Sadri-Vakili G, Kumaresan V, Schmidt HD, Bass CE, Terwilliger EF, Cha JH, Pierce RC. CaMKII: a biochemical bridge linking accumbens dopamine and glutamate systems in cocaine seeking. Nature Neuroscience. 11: 344-53. PMID 18278040 DOI: 10.1038/nn2054  0.92
2008 Anderson SM, Famous KR, Sadri-Vakili G, Kumaresan V, Schmidt HD, Bass CE, Terwilliger EF, Cha JHJ, Pierce RC. CaMKII: A biochemical bridge linking accumbens dopamine and glutamate systems in cocaine seeking (Nature Neuroscience (2008) 11, 344-353) Nature Neuroscience. 11: 617. DOI: 10.1038/nn0508-617  0.92
2007 Balcioglu A, Kim MO, Sharma N, Cha JH, Breakefield XO, Standaert DG. Dopamine release is impaired in a mouse model of DYT1 dystonia. Journal of Neurochemistry. 102: 783-8. PMID 17550429 DOI: 10.1111/j.1471-4159.2007.04590.x  0.4
2007 Benn CL, Slow EJ, Farrell LA, Graham R, Deng Y, Hayden MR, Cha JH. Glutamate receptor abnormalities in the YAC128 transgenic mouse model of Huntington's disease. Neuroscience. 147: 354-72. PMID 17544587 DOI: 10.1016/j.neuroscience.2007.03.010  0.92
2007 Kuhn A, Goldstein DR, Hodges A, Strand AD, Sengstag T, Kooperberg C, Becanovic K, Pouladi MA, Sathasivam K, Cha JH, Hannan AJ, Hayden MR, Leavitt BR, Dunnett SB, Ferrante RJ, et al. Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage. Human Molecular Genetics. 16: 1845-61. PMID 17519223 DOI: 10.1093/hmg/ddm133  0.92
2007 Cha JH. Transcriptional signatures in Huntington's disease. Progress in Neurobiology. 83: 228-48. PMID 17467140 DOI: 10.1016/j.pneurobio.2007.03.004  0.92
2007 Sadri-Vakili G, Bouzou B, Benn CL, Kim MO, Chawla P, Overland RP, Glajch KE, Xia E, Qiu Z, Hersch SM, Clark TW, Yohrling GJ, Cha JH. Histones associated with downregulated genes are hypo-acetylated in Huntington's disease models. Human Molecular Genetics. 16: 1293-306. PMID 17409194 DOI: 10.1093/hmg/ddm078  0.92
2007 Cha JH. Finding diamonds in the rubble. Experimental Neurology. 205: 1-4. PMID 17376435 DOI: 10.1016/j.expneurol.2007.02.003  0.92
2006 Xiao D, Bastia E, Xu YH, Benn CL, Cha JH, Peterson TS, Chen JF, Schwarzschild MA. Forebrain adenosine A2A receptors contribute to L-3,4-dihydroxyphenylalanine-induced dyskinesia in hemiparkinsonian mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 13548-55. PMID 17192438 DOI: 10.1523/JNEUROSCI.3554-06.2006  0.92
2006 Cha JH, Furie K, Kay J, Walensky RP, Mullins ME, Hedley-Whyte ET. Case records of the Massachusetts General Hospital. Case 39-2006. A 24-year-old woman with systemic lupus erythematosus, seizures, and right arm weakness. The New England Journal of Medicine. 355: 2678-89. PMID 17182994 DOI: 10.1056/NEJMcpc069030  0.92
2006 Sadri-Vakili G, Cha JH. Histone deacetylase inhibitors: a novel therapeutic approach to Huntington's disease (complex mechanism of neuronal death). Current Alzheimer Research. 3: 403-8. PMID 17017871 DOI: 10.2174/156720506778249407  0.92
2006 Sadri-Vakili G, Cha JH. Mechanisms of disease: Histone modifications in Huntington's disease. Nature Clinical Practice. Neurology. 2: 330-8. PMID 16932577 DOI: 10.1038/ncpneuro0199  0.92
2006 Li JL, Hayden MR, Warby SC, Durr A, Morrison PJ, Nance M, Ross CA, Margolis RL, Rosenblatt A, Squitieri F, Frati L, Gómez-Tortosa E, García CA, Suchowersky O, Klimek ML, ... ... Cha JH, et al. Genome-wide significance for a modifier of age at neurological onset in Huntington's disease at 6q23-24: the HD MAPS study. Bmc Medical Genetics. 7: 71. PMID 16914060 DOI: 10.1186/1471-2350-7-71  0.92
2006 Qiu Z, Norflus F, Singh B, Swindell MK, Buzescu R, Bejarano M, Chopra R, Zucker B, Benn CL, DiRocco DP, Cha JH, Ferrante RJ, Hersch SM. Sp1 is up-regulated in cellular and transgenic models of Huntington disease, and its reduction is neuroprotective. The Journal of Biological Chemistry. 281: 16672-80. PMID 16595660 DOI: 10.1074/jbc.M511648200  0.92
2006 Chen-Plotkin AS, Sadri-Vakili G, Yohrling GJ, Braveman MW, Benn CL, Glajch KE, DiRocco DP, Farrell LA, Krainc D, Gines S, MacDonald ME, Cha JH. Decreased association of the transcription factor Sp1 with genes downregulated in Huntington's disease. Neurobiology of Disease. 22: 233-41. PMID 16442295 DOI: 10.1016/j.nbd.2005.11.001  0.92
2005 Benn CL, Landles C, Li H, Strand AD, Woodman B, Sathasivam K, Li SH, Ghazi-Noori S, Hockly E, Faruque SM, Cha JH, Sharpe PT, Olson JM, Li XJ, Bates GP. Contribution of nuclear and extranuclear polyQ to neurological phenotypes in mouse models of Huntington's disease. Human Molecular Genetics. 14: 3065-78. PMID 16183657 DOI: 10.1093/hmg/ddi340  0.92
2004 Braveman MW, Chen-Plotkin AS, Yohrling GJ, Cha JH. Chromatin immunoprecipitation technique for study of transcriptional dysregulation in intact mouse brain. Methods in Molecular Biology (Clifton, N.J.). 277: 261-76. PMID 15201461 DOI: 10.1385/1-59259-804-8:261  0.92
2004 Benn CL, Farrell LA, Cha JH. Neurotransmitter receptor analysis in transgenic mouse models. Methods in Molecular Biology (Clifton, N.J.). 277: 231-60. PMID 15201460 DOI: 10.1385/1-59259-804-8:231  0.92
2003 Luthi-Carter R, Apostol BL, Dunah AW, DeJohn MM, Farrell LA, Bates GP, Young AB, Standaert DG, Thompson LM, Cha JH. Complex alteration of NMDA receptors in transgenic Huntington's disease mouse brain: analysis of mRNA and protein expression, plasma membrane association, interacting proteins, and phosphorylation. Neurobiology of Disease. 14: 624-36. PMID 14678777 DOI: 10.1016/j.nbd.2003.08.024  0.92
2003 Yohrling GJ, Jiang GC, DeJohn MM, Miller DW, Young AB, Vrana KE, Cha JH. Analysis of cellular, transgenic and human models of Huntington's disease reveals tyrosine hydroxylase alterations and substantia nigra neuropathology. Brain Research. Molecular Brain Research. 119: 28-36. PMID 14597227 DOI: 10.1016/j.molbrainres.2003.08.009  0.92
2003 Li JL, Hayden MR, Almqvist EW, Brinkman RR, Durr A, Dodé C, Morrison PJ, Suchowersky O, Ross CA, Margolis RL, Rosenblatt A, Gómez-Tortosa E, Cabrero DM, Novelletto A, Frontali M, ... ... Cha JH, et al. A genome scan for modifiers of age at onset in Huntington disease: The HD MAPS study. American Journal of Human Genetics. 73: 682-7. PMID 12900792 DOI: 10.1086/378133  0.92
2003 Yohrling GJ, Farrell LA, Hollenberg AN, Cha JH. Mutant huntingtin increases nuclear corepressor function and enhances ligand-dependent nuclear hormone receptor activation. Molecular and Cellular Neurosciences. 23: 28-38. PMID 12799135 DOI: 10.1016/S1044-7431(03)00032-0  0.92
2003 Gomez-Isla T, Irizarry MC, Mariash A, Cheung B, Soto O, Schrump S, Sondel J, Kotilinek L, Day J, Schwarzschild MA, Cha JH, Newell K, Miller DW, Uéda K, Young AB, et al. Motor dysfunction and gliosis with preserved dopaminergic markers in human alpha-synuclein A30P transgenic mice. Neurobiology of Aging. 24: 245-58. PMID 12498958 DOI: 10.1016/S0197-4580(02)00091-X  0.92
2002 Yohrling IV GJ, Jiang GC, DeJohn MM, Robertson DJ, Vrana KE, Cha JH. Inhibition of tryptophan hydroxylase activity and decreased 5-HT1A receptor binding in a mouse model of Huntington's disease. Journal of Neurochemistry. 82: 1416-23. PMID 12354289 DOI: 10.1046/j.1471-4159.2002.01084.x  0.92
2002 Chan EY, Luthi-Carter R, Strand A, Solano SM, Hanson SA, DeJohn MM, Kooperberg C, Chase KO, DiFiglia M, Young AB, Leavitt BR, Cha JH, Aronin N, Hayden MR, Olson JM. Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington's disease. Human Molecular Genetics. 11: 1939-51. PMID 12165556  0.92
2001 Cha JH, Farrell LA, Ahmed SF, Frey A, Hsiao-Ashe KK, Young AB, Penney JB, Locascio JJ, Hyman BT, Irizarry MC. Glutamate receptor dysregulation in the hippocampus of transgenic mice carrying mutated human amyloid precursor protein. Neurobiology of Disease. 8: 90-102. PMID 11162243 DOI: 10.1006/nbdi.2000.0330  0.92
2000 Chen M, Ona VO, Li M, Ferrante RJ, Fink KB, Zhu S, Bian J, Guo L, Farrell LA, Hersch SM, Hobbs W, Vonsattel JP, Cha JH, Friedlander RM. Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease. Nature Medicine. 6: 797-801. PMID 10888929 DOI: 10.1038/77528  0.92
1999 Kosinski CM, Cha JH, Young AB, Schwarz M. [Huntington chorea. Animal models reveal new hypotheses for pathophysiology and therapy]. Der Nervenarzt. 70: 878-88. PMID 10554779 DOI: 10.1007/s001150050591  0.72
1999 Ona VO, Li M, Vonsattel JP, Andrews LJ, Khan SQ, Chung WM, Frey AS, Menon AS, Li XJ, Stieg PE, Yuan J, Penney JB, Young AB, Cha JH, Friedlander RM. Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease. Nature. 399: 263-7. PMID 10353249 DOI: 10.1038/20446  0.92
1997 Kosinski CM, Cha JH, Young AB, Persichetti F, MacDonald M, Gusella JF, Penney JB, Standaert DG. Huntingtin immunoreactivity in the rat neostriatum: differential accumulation in projection and interneurons. Experimental Neurology. 144: 239-47. PMID 9168825 DOI: 10.1006/exnr.1997.6441  0.4
1991 Cha JH, Dure LS IV, Sakurai SY, Penney JB, Young AB. 2,4,5-Trihydroxyphenylalanine (6-hydroxy-dopa) displaces [3H]AMPA binding in rat striatum. Neuroscience Letters. 132: 55-8. PMID 1664920 DOI: 10.1016/0304-3940(91)90432-S  0.92
1990 Makowiec RL, Albin RL, Cha JH, Young AB, Gilman S. Two types of quisqualate receptors are decreased in human olivopontocerebellar atrophy cerebellar cortex. Brain Research. 523: 309-12. PMID 1976026  0.72
1990 Cha JH, Makowiec RL, Penney JB, Young AB. L-[3H]glutamate labels the metabotropic excitatory amino acid receptor in rodent brain. Neuroscience Letters. 113: 78-83. PMID 1973276 DOI: 10.1016/0304-3940(90)90498-X  0.92
1989 Cha JH, Hollingsworth ZR, Greenamyre JT, Young AB. Contamination of commercially available quisqualic acid by glutamate-like and aspartate-like substances. Journal of Neuroscience Methods. 27: 143-8. PMID 2565415 DOI: 10.1016/0165-0270(89)90097-6  0.92
1986 Cha JH, O'Brien DR, Dowling JE. Effects of D-aspartate on excitatory amino acid-induced release of [3H]GABA from goldfish retina. Brain Research. 376: 140-8. PMID 2872943 DOI: 10.1016/0006-8993(86)90908-X  0.92
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