Anne B. Young, MD PhD - Related publications

Affiliations: 
Neurology Massachusetts General Hospital, Boston, MA 
 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Basal Ganglia, Glutamate Receptors, Huntington's Disease
Website:
http://www.mghmind.org/Faculty/young_anne.html
NOTE: We are testing a new system for identifying relevant work based on semantic analysis that identifies similarities between recently published papers and the current author's publications. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches.
50 most relevant papers in past 60 days:
Year Citation  Score
2020 Ortega G, Mariottini D, Troina A, Dahlquist FW, Ricci F, Plaxco KW. Rational design to control the trade-off between receptor affinity and cooperativity. Proceedings of the National Academy of Sciences of the United States of America. PMID 32727893 DOI: 10.1073/pnas.2006254117   
2020 McGrath M, Hoyt H, Pence A, Jayakar SS, Zhou X, Forman SA, Cohen JB, Miller KW, Raines DE. Competitive Antagonism of Etomidate Action by Diazepam: In Vitro GABAA Receptor and In Vivo Zebrafish Studies. Anesthesiology. PMID 32541553 DOI: 10.1097/ALN.0000000000003403   
2020 Salazar H, Mischke S, Plested AJR. Measurements of the Timescale and Conformational Space of AMPA Receptor Desensitization. Biophysical Journal. PMID 32559412 DOI: 10.1016/j.bpj.2020.05.029   
2020 Che C, Zeng Y, Xu Y, Lu H, Xu Y, Zhang X, Xiao Y, Li JQ, Qin Z. APAn, a Class of ABA Receptor Agonism/antagonism Switching Probes. Journal of Agricultural and Food Chemistry. PMID 32687337 DOI: 10.1021/acs.jafc.0c02154   
2020 Lillo A, Martínez-Pinilla E, Reyes-Resina I, Navarro G, Franco R. Adenosine A and A Receptors Are Able to Interact with Each Other. A Further Piece in the Puzzle of Adenosine Receptor-Mediated Signaling. International Journal of Molecular Sciences. 21. PMID 32709103 DOI: 10.3390/ijms21145070   
2020 Akk G, Germann AL, Sugasawa Y, Pierce SR, Evers AS, Steinbach JH. Enhancement of muscimol binding and gating by allosteric modulators of the GABA receptor: relating occupancy to state functions. Molecular Pharmacology. PMID 32723768 DOI: 10.1124/molpharm.120.000066   
2020 Chou TH, Tajima N, Romero-Hernandez A, Furukawa H. Structural Basis of Functional Transitions in Mammalian NMDA Receptors. Cell. PMID 32610085 DOI: 10.1016/j.cell.2020.05.052   
2020 Brimson JM, Akula KK, Abbas H, Ferry DR, Kulkarni SK, Russell ST, Tisdale MJ, Tencomnao T, Safrany ST. Simple ammonium salts acting on sigma-1 receptors yield potential treatments for cancer and depression. Scientific Reports. 10: 9251. PMID 32514120 DOI: 10.1038/s41598-020-65849-6   
2020 Bres EE, Safina D, Müller J, Bedner P, Yang H, Helluy X, Shchyglo O, Jansen S, Mark MD, Esser A, Steinhäuser C, Herlitze S, Pietrzik CU, Sirko S, Manahan-Vaughan D, et al. Lipoprotein receptor loss in forebrain radial glia results in neurological deficits and severe seizures. Glia. PMID 32579270 DOI: 10.1002/glia.23869   
2020 Zhang W, Liu QY, Haqqani AS, Leclerc S, Liu Z, Fauteux F, Baumann E, Delaney CE, Ly D, Star AT, Brunette E, Sodja C, Hewitt M, Sandhu JK, Stanimirovic DB. Differential expression of receptors mediating receptor-mediated transcytosis (RMT) in brain microvessels, brain parenchyma and peripheral tissues of the mouse and the human. Fluids and Barriers of the Cns. 17: 47. PMID 32698806 DOI: 10.1186/s12987-020-00209-0   
2020 Stephens BS, Ngo T, Kufareva I, Handel TM. Functional anatomy of the full-length CXCR4-CXCL12 complex systematically dissected by quantitative model-guided mutagenesis. Science Signaling. 13. PMID 32665413 DOI: 10.1126/scisignal.aay5024   
2020 Rauschenberger V, Wardenburg NV, Schaefer N, Ogino K, Hirata H, Lillesaar C, Kluck CJ, Meinck HM, Borrmann M, Weishaupt A, Doppler K, Wickel J, Geis C, Sommer C, Villmann C. GlyR autoantibodies impair receptor function and induce motor dysfunction. Annals of Neurology. PMID 32588476 DOI: 10.1002/ana.25832   
2020 Gutjahr A, Papagno L, Vernejoul F, Lioux T, Jospin F, Chanut B, Perouzel E, Rochereau N, Appay V, Verrier B, Paul S. New chimeric TLR7/NOD2 agonist is a potent adjuvant to induce mucosal immune responses. Ebiomedicine. 58: 102922. PMID 32739871 DOI: 10.1016/j.ebiom.2020.102922   
2020 Gutjahr A, Papagno L, Vernejoul F, Lioux T, Jospin F, Chanut B, Perouzel E, Rochereau N, Appay V, Verrier B, Paul S. New chimeric TLR7/NOD2 agonist is a potent adjuvant to induce mucosal immune responses. Ebiomedicine. 58: 102922. PMID 32739871 DOI: 10.1016/j.ebiom.2020.102922   
2020 Riad A, Lengyel-Zhand Z, Zeng C, Weng CC, Lee VM, Trojanowski JQ, Mach RH. The Sigma-2 Receptor/TMEM97, PGRMC1, and LDL Receptor Complex Are Responsible for the Cellular Uptake of Aβ42 and Its Protein Aggregates. Molecular Neurobiology. PMID 32572762 DOI: 10.1007/s12035-020-01988-1   
2020 Liu R, Zhang M, Liu L, Chen G, Hou Y, Wang M, Li J. Neuronal Surface Antibody Syndrome: A Review of the Characteristics of the Disease and Its Association with Autoantibodies. Neuroimmunomodulation. 1-8. PMID 32554968 DOI: 10.1159/000507448   
2020 Nasrollahi-Shirazi S, Szöllösi D, Yang Q, Muratspahic E, El-Kasaby A, Sucic S, Stockner T, Nanoff C, Freissmuth M. Functional impact of the G279S substitution in the adenosine A1-receptor (A1R-G279S), a mutation associated with Parkinson's disease. Molecular Pharmacology. PMID 32641371 DOI: 10.1124/molpharm.120.000003   
2020 Chen BP, Huang XX, Dong DM, Wu H, Zhu TQ, Wang BF. The role of NMDA receptors in rat propofol self-administration. Bmc Anesthesiology. 20: 149. PMID 32539742 DOI: 10.1186/s12871-020-01056-0   
2020 Sánchez-Melgar A, Albasanz JL, Griñán-Ferré C, Pallàs M, Martín M. Adenosine and Metabotropic Glutamate Receptors Are Present in Blood Serum and Exosomes from SAMP8 Mice: Modulation by Aging and Resveratrol. Cells. 9. PMID 32645849 DOI: 10.3390/cells9071628   
2020 Yang X, Dilweg MA, Osemwengie D, Burggraaff L, van der Es D, Heitman LH, IJzerman AP. Design and Pharmacological Profile of a Novel Covalent Partial Agonist for the Adenosine A Receptor. Biochemical Pharmacology. 114144. PMID 32653590 DOI: 10.1016/j.bcp.2020.114144   
2020 Cui Y, Peng R, Song H, Tong Z, Qu X, Liu S, Zhao X, Chai Y, Wang P, Gao GF, Qi J. Molecular basis of Coxsackievirus A10 entry using the two-in-one attachment and uncoating receptor KRM1. Proceedings of the National Academy of Sciences of the United States of America. PMID 32690697 DOI: 10.1073/pnas.2005341117   
2020 Cui Y, Peng R, Song H, Tong Z, Qu X, Liu S, Zhao X, Chai Y, Wang P, Gao GF, Qi J. Molecular basis of Coxsackievirus A10 entry using the two-in-one attachment and uncoating receptor KRM1. Proceedings of the National Academy of Sciences of the United States of America. PMID 32690697 DOI: 10.1073/pnas.2005341117   
2020 Tian J, He Y, Deuther-Conrad W, Fu H, Xie F, Zhang Y, Wang T, Zhang X, Zhang J, Brust P, Huang Y, Jia H. Synthesis and evaluation of new 1-oxa-8-azaspiro[4.5]decane derivatives as candidate radioligands for sigma-1 receptors. Bioorganic & Medicinal Chemistry. 28: 115560. PMID 32616183 DOI: 10.1016/j.bmc.2020.115560   
2020 Sakiyama Y, Matsuura E, Shigehisa A, Hamada Y, Dozono M, Nozuma S, Nakamura T, Higashi K, Hashiguchi A, Takahashi Y, Takashima H. Cryptococcus Meningitis Can Co-occur with Anti-NMDA Receptor Encephalitis. Internal Medicine (Tokyo, Japan). PMID 32522922 DOI: 10.2169/internalmedicine.4629-20   
2020 Germann AL, Reichert DE, Burbridge AB, Pierce SR, Evers AS, Steinbach JH, Akk G. Analysis of modulation of the ρ1 GABAA receptor by combinations of inhibitory and potentiating neurosteroids reveals shared and distinct binding sites. Molecular Pharmacology. PMID 32675382 DOI: 10.1124/mol.120.119842   
2020 He YC, Yan YM, Tong HB, Ren ZX, Wang JH, Zhang YB, Chao JB, Wang ML. Benzenebistriazole-strapped calix[4]pyrrole: a neutral anion receptor with CH and NH donor groups that exhibits high sulfate binding affinity and selectivity in aqueous solutions. Chemical Communications (Cambridge, England). PMID 32672309 DOI: 10.1039/d0cc03655b   
2020 Fischer JP, Els-Heindl S, Beck-Sickinger AG. Adrenomedullin - Current Perspective on a Peptide Hormone with Significant Therapeutic Potential. Peptides. 170347. PMID 32569606 DOI: 10.1016/j.peptides.2020.170347   
2020 Intagliata S, Sharma A, King TI, Mesangeau C, Seminerio M, Chin FT, Wilson LL, Matsumoto RR, McLaughlin JP, Avery BA, McCurdy CR. Discovery of a Highly Selective Sigma-2 Receptor Ligand, 1-(4-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)butyl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one (CM398), with Drug-Like Properties and Antinociceptive Effects In Vivo. The Aaps Journal. 22: 94. PMID 32691179 DOI: 10.1208/s12248-020-00472-x   
2020 Spillmann M, Thurner L, Romantini N, Zimmermann M, Meger B, Behe M, Waldhoer M, Schertler GFX, Berger P. New Insights into Arrestin Recruitment to GPCRs. International Journal of Molecular Sciences. 21. PMID 32668755 DOI: 10.3390/ijms21144949   
2020 Yu Liao VW, Kusay AS, Balle T, Ahring PK. Heterologous expression of concatenated nicotine acetylcholine receptors: pros and cons of subunit concatenation and recommendations for construct designs. British Journal of Pharmacology. PMID 32627170 DOI: 10.1111/bph.15188   
2020 Bekker R, Fjellaksel R, Hjornevik T, Nuruddin S, Rafique W, Hansen J, Sundset R, Haraldsen I, Riß PJ. Discovery of a lead brain-penetrating gonadotropin releasing hormone receptor antagonist with saturable binding in brain. Chemmedchem. PMID 32677155 DOI: 10.1002/cmdc.202000256   
2020 Krintel C, Dorosz J, Larsen AH, Seneca Thorsen T, Venskutonytė R, Mirza O, Gajhede M, Boesen T, Kastrup JS. Binding of a negative allosteric modulator and competitive antagonist can occur simultaneously at the ionotropic glutamate receptor GluA2. The Febs Journal. PMID 32543078 DOI: 10.1111/febs.15455   
2020 Liu X, Guo L, Liang C. [Research progress on electroencephalogram characteristics of anti-N-methyl-D-aspartate receptor encephalitis]. Zhejiang Da Xue Xue Bao. Yi Xue Ban = Journal of Zhejiang University. Medical Sciences. 49: 118-123. PMID 32621409   
2020 Abbott JA, Popescu GK. Hydroxynorketamine Blocks NMDA Receptor Currents by Binding to Closed Receptors. Molecular Pharmacology. PMID 32606205 DOI: 10.1124/mol.120.119784   
2020 Roderer D, Bröcker F, Sitsel O, Kaplonek P, Leidreiter F, Seeberger PH, Raunser S. Glycan-dependent cell adhesion mechanism of Tc toxins. Nature Communications. 11: 2694. PMID 32483155 DOI: 10.1038/s41467-020-16536-7   
2020 Falk-Petersen CB, Tsonkov TM, Nielsen MS, Harpsøe K, Bundgaard C, Frølund B, Kristiansen U, Gloriam DE, Wellendorph P. Discovery of a new class of orthosteric antagonists with nanomolar potency at extrasynaptic GABA receptors. Scientific Reports. 10: 10078. PMID 32572053 DOI: 10.1038/s41598-020-66821-0   
2020 Zmonarski SC, Miroslaw B, Tomasz G, Katarzyna M, Oktawia M, Marta M, Joanna Z, Krzysztof L, Tomasz D, Magdalena K. Toll-like 4 receptor (TLR4) expression on peripheral blood mononuclear cells in renal transplant recipients with pre-transplant chronic interstitial nephritis indicates patients at risk of graft deterioration. Transplant Immunology. 101319. PMID 32693120 DOI: 10.1016/j.trim.2020.101319   
2020 Segura-Chama P, Luis E, Almanza A, Pellicer F, Hernández-Cruz A, Mercado F. Modulation of intracellular calcium concentration by D2-like DA receptor agonists in non-peptidergic DRG neurons is mediated mainly by D4 receptor activation. Neuroscience Letters. 135267. PMID 32717335 DOI: 10.1016/j.neulet.2020.135267   
2020 Richendrfer HA, Levy MM, Elsaid KA, Schmidt TA, Zhang L, Cabezas R, Jay GD. Recombinant Human Proteoglycan-4 Mediates Interleukin-6 Response in Both Human and Mouse Endothelial Cells Induced Into a Sepsis Phenotype. Critical Care Explorations. 2: e0126. PMID 32695993 DOI: 10.1097/CCE.0000000000000126   
2020 Clark LJ, Krieger J, White AD, Bondarenko V, Lei S, Fang F, Lee JY, Doruker P, Böttke T, Jean-Alphonse F, Tang P, Gardella TJ, Xiao K, Sutkeviciute I, Coin I, et al. Allosteric interactions in the parathyroid hormone GPCR-arrestin complex formation. Nature Chemical Biology. PMID 32632293 DOI: 10.1038/s41589-020-0567-0   
2020 Gao C, Zeng J, Jia N, Stavenhagen K, Matsumoto Y, Zhang H, Li J, Hume AJ, Mühlberger E, van Die I, Kwan J, Tantisira K, Emili A, Cummings RD. SARS-CoV-2 Spike Protein Interacts with Multiple Innate Immune Receptors. Biorxiv : the Preprint Server For Biology. PMID 32766577 DOI: 10.1101/2020.07.29.227462   
2020 Brown RW, Bhide PG, Gill WD, Peeters LD. The adenosine A(2A) receptor agonist CGS 21680 alleviates auditory sensorimotor gating deficits and increases in accumbal CREB in rats neonatally treated with quinpirole. Psychopharmacology. PMID 32772144 DOI: 10.1007/s00213-020-05631-8   
2020 Souza RF, Evangelinellis MM, Mendes CE, Righetti M, Lourenço MCS, Castelucci P. P2X7 receptor antagonist recovers ileum myenteric neurons after experimental ulcerative colitis. World Journal of Gastrointestinal Pathophysiology. 11: 84-103. PMID 32587788 DOI: 10.4291/wjgp.v11.i4.84   
2020 Masih A, Singh S, Agnihotri AK, Giri S, Shrivastava JK, Pandey N, Bhat HR, Singh UP. Design and development of 1,3,5-triazine-thiadiazole hybrids as potent adenosine AA receptor (AAR) antagonist for benefit in Parkinson's Disease. Neuroscience Letters. 135222. PMID 32619652 DOI: 10.1016/j.neulet.2020.135222   
2020 Motawe ZY, Abdelmaboud SS, Cuevas J, Breslin JW. PRE-084 as a tool to uncover potential therapeutic applications for selective sigma-1 receptor activation. The International Journal of Biochemistry & Cell Biology. 126: 105803. PMID 32668330 DOI: 10.1016/j.biocel.2020.105803   
2020 Harada R, Hayakawa Y, Ezura M, Lerdsirisuk P, Du Y, Ishikawa Y, Iwata R, Shidahara M, Ishiki A, Kikuchi A, Arai H, Kudo Y, Yanai K, Furumoto S, Okamura N. F-SMBT-1: A Selective and Reversible Positron-Emission Tomography Tracer for Monoamine Oxidase-B Imaging. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 32646880 DOI: 10.2967/jnumed.120.244400   
2020 Al Noman MA, Kyzer J, Chung SSW, Wolgemuth DJ, Georg GI. Retinoic acid receptor antagonists for male contraception: Current status. Biology of Reproduction. PMID 32671394 DOI: 10.1093/biolre/ioaa122   
2020 Magno AL, Leatherbarrow KM, Brown SJ, Wilson SG, Walsh JP, Ward BK. Functional Analysis of Calcium-Sensing Receptor Variants Identified in Families Provisionally Diagnosed with Familial Hypocalciuric Hypercalcaemia. Calcified Tissue International. PMID 32638038 DOI: 10.1007/s00223-020-00715-1   
2020 Kovtun O, Torres R, Ferguson RS, Josephs T, Rosenthal SJ. Single Quantum Dot Tracking Unravels Agonist Effects on the Dopamine Receptor Dynamics. Biochemistry. PMID 32584548 DOI: 10.1021/acs.biochem.0c00360   
2020 Perl S, Richter F, Richter A. Striatal and cortical metabotropic glutamate 5 receptor expression and behavioral effects of the positive allosteric modulator CDPPB in a model of DYT1 dystonia. Pharmacology, Biochemistry, and Behavior. 172977. PMID 32615137 DOI: 10.1016/j.pbb.2020.172977