David Kaplan - Publications

Affiliations: 
SickKids Hospital, Toronto, Toronto, Ontario, Canada 
Area:
Neurotrophins

183 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Mahmud N, Kaplan DE, Goldberg DS, Taddei TH, Serper M. Changes in Hepatocellular Carcinoma Surveillance and Risk Factors for Non-Completion in the VHA Cohort During the COVID-19 Pandemic. Gastroenterology. PMID 33434604 DOI: 10.1053/j.gastro.2021.01.007  0.48
2020 Mahmud N, Kaplan DE, Taddei TH, Goldberg DS. Frailty is a Risk Factor for Post-Operative Mortality in Patients with Cirrhosis Undergoing Diverse Major Surgeries. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. PMID 33226691 DOI: 10.1002/lt.25953  0.48
2020 Jeong D, Lozano Casasbuenas D, Gengatharan A, Edwards K, Saghatelyan A, Kaplan DR, Miller FD, Yuzwa SA. LRIG1-Mediated Inhibition of EGF Receptor Signaling Regulates Neural Precursor Cell Proliferation in the Neocortex. Cell Reports. 33: 108257. PMID 33053360 DOI: 10.1016/j.celrep.2020.108257  1
2020 Mahmud N, Asrani SK, Kaplan DE, Ogola GO, Taddei TH, Kamath PS, Serper M. The Predictive Role of MELD-Lactate and Lactate Clearance for In-Hospital Mortality among a National Cirrhosis Cohort. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. PMID 33025731 DOI: 10.1002/lt.25913  0.48
2020 Shah S, Goldberg DS, Kaplan DE, Sundaram V, Taddei TH, Mahmud N. Patient Frailty is Independently Associated with the Risk of Acute on Chronic Liver Failure Hospitalization. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. PMID 32946660 DOI: 10.1002/lt.25896  0.48
2020 Mahmud N, Fricker Z, Hubbard RA, Ioannou GN, Lewis JD, Taddei TH, Rothstein KD, Serper M, Goldberg DS, Kaplan DE. Novel Risk Prediction Models for Post-Operative Mortality in Patients with Cirrhosis. Hepatology (Baltimore, Md.). PMID 32939786 DOI: 10.1002/hep.31558  0.48
2020 Borrett MJ, Innes BT, Jeong D, Tahmasian N, Storer MA, Bader GD, Kaplan DR, Miller FD. Single-Cell Profiling Shows Murine Forebrain Neural Stem Cells Reacquire a Developmental State when Activated for Adult Neurogenesis. Cell Reports. 32: 108022. PMID 32783944 DOI: 10.1016/j.celrep.2020.108022  1
2020 Xiao KY, Hubbard RA, Kaplan DE, Taddei TH, Goldberg DS, Mahmud N. Models for acute on chronic liver failure development and mortality in a veterans affairs cohort. Hepatology International. PMID 32519219 DOI: 10.1007/s12072-020-10060-y  0.48
2020 Mahmud N, Hubbard RA, Kaplan DE, Serper M. Declining Cirrhosis Hospitalizations in the Wake of the COVID-19 Pandemic: A National Cohort Study. Gastroenterology. PMID 32387493 DOI: 10.1053/j.gastro.2020.05.005  0.48
2020 Toma JS, Karamboulas K, Carr MJ, Kolaj A, Yuzwa SA, Mahmud N, Storer MA, Kaplan DR, Miller FD. Peripheral Nerve Single Cell Analysis Identifies Mesenchymal Ligands that Promote Axonal Growth. Eneuro. PMID 32349983 DOI: 10.1523/ENEURO.0066-20.2020  1
2020 Rodrigues DC, Harvey EM, Suraj R, Erickson SL, Mohammad L, Ren M, Liu H, He G, Kaplan DR, Ellis J, Yang G. Methylglyoxal couples metabolic and translational control of Notch signalling in mammalian neural stem cells. Nature Communications. 11: 2018. PMID 32332750 DOI: 10.1038/s41467-020-15941-2  0.68
2020 Tomita H, Cornejo F, Aranda-Pino B, Woodard CL, Rioseco CC, Neel BG, Alvarez AR, Kaplan DR, Miller FD, Cancino GI. The Protein Tyrosine Phosphatase Receptor Delta Regulates Developmental Neurogenesis. Cell Reports. 30: 215-228.e5. PMID 31914388 DOI: 10.1016/j.celrep.2019.11.033  1
2019 Storer MA, Mahmud N, Karamboulas K, Borrett MJ, Yuzwa SA, Gont A, Androschuk A, Sefton MV, Kaplan DR, Miller FD. Acquisition of a Unique Mesenchymal Precursor-like Blastema State Underlies Successful Adult Mammalian Digit Tip Regeneration. Developmental Cell. PMID 31902657 DOI: 10.1016/j.devcel.2019.12.004  1
2019 Mahmud N, Hubbard RA, Kaplan DE, Taddei TH, Goldberg DS. Risk Prediction Scores for Acute on Chronic Liver Failure Development and Mortality. Liver International : Official Journal of the International Association For the Study of the Liver. PMID 31840390 DOI: 10.1111/liv.14328  0.48
2019 Mahmud N, Sundaram V, Kaplan DE, Taddei TH, Goldberg DS. Grade 1 Acute on Chronic Liver Failure is a Predictor for Subsequent Grade 3 Failure. Hepatology (Baltimore, Md.). PMID 31677284 DOI: 10.1002/hep.31012  0.48
2019 Zahr SK, Kaplan DR, Miller FD. Translating neural stem cells to neurons in the mammalian brain. Cell Death and Differentiation. PMID 31551564 DOI: 10.1038/s41418-019-0411-9  1
2019 Kanneganti M, Mahmud N, Kaplan DE, Taddei TH, Goldberg DS. Survival Benefit of Liver Transplantation for Hepatocellular Carcinoma. Transplantation. PMID 31283688 DOI: 10.1097/TP.0000000000002816  0.48
2019 Mahmud N, Kaplan DE, Taddei TH, Goldberg DS. Reply to Letters to the Editor: Diverging Definitions and Dividing Lines in Acute-on-Chronic Liver Failure. Hepatology (Baltimore, Md.). PMID 31243784 DOI: 10.1002/hep.30835  0.48
2019 Mahmud N, Fricker Z, Serper M, Kaplan DE, Rothstein KD, Goldberg DS. In-Hospital Mortality Varies by Procedure Type among Cirrhosis Surgery Admissions. Liver International : Official Journal of the International Association For the Study of the Liver. PMID 31141306 DOI: 10.1111/liv.14156  0.48
2019 Mahmud N, Kaplan DE, Taddei TH, Goldberg DS. Incidence and Mortality of Acute on Chronic Liver Failure using Two Definitions in Patients with Compensated Cirrhosis. Hepatology (Baltimore, Md.). PMID 30615211 DOI: 10.1002/hep.30494  0.48
2018 Carr MJ, Toma JS, Johnston APW, Steadman PE, Yuzwa SA, Mahmud N, Frankland PW, Kaplan DR, Miller FD. Mesenchymal Precursor Cells in Adult Nerves Contribute to Mammalian Tissue Repair and Regeneration. Cell Stem Cell. PMID 30503141 DOI: 10.1016/j.stem.2018.10.024  1
2018 Qazi MA, Vora P, Venugopal C, Adams J, Singh M, Hu AX, Gorelik M, Subapanditha MK, Savage N, Yang J, Chokshi C, London M, Gont A, Bobrowski D, Grinshtein N, ... ... Kaplan DR, et al. Co-targeting ephrin receptor tyrosine kinases A2 and A3 in cancer stem cells reduces growth of recurrent glioblastoma. Cancer Research. PMID 29945963 DOI: 10.1158/0008-5472.CAN-18-0267  0.48
2018 Storer MA, Gallagher D, Fatt MP, Simonetta JV, Kaplan DR, Miller FD. Interleukin-6 Regulates Adult Neural Stem Cell Numbers during Normal and Abnormal Post-natal Development. Stem Cell Reports. PMID 29628394 DOI: 10.1016/j.stemcr.2018.03.008  1
2018 Zahr SK, Yang G, Kazan H, Borrett MJ, Yuzwa SA, Voronova A, Kaplan DR, Miller FD. A Translational Repression Complex in Developing Mammalian Neural Stem Cells that Regulates Neuronal Specification. Neuron. PMID 29395907 DOI: 10.1016/j.neuron.2017.12.045  1
2017 Yuzwa SA, Borrett MJ, Innes BT, Voronova A, Ketela T, Kaplan DR, Bader GD, Miller FD. Developmental Emergence of Adult Neural Stem Cells as Revealed by Single-Cell Transcriptional Profiling. Cell Reports. 21: 3970-3986. PMID 29281841 DOI: 10.1016/j.celrep.2017.12.017  1
2017 Feinberg K, Kolaj A, Wu C, Grinshtein N, Krieger JR, Moran MF, Rubin LL, Miller FD, Kaplan DR. A neuroprotective agent that inactivates prodegenerative TrkA and preserves mitochondria. The Journal of Cell Biology. PMID 28877995 DOI: 10.1083/jcb.201705085  1
2017 Voronova A, Yuzwa SA, Wang BS, Zahr S, Syal C, Wang J, Kaplan DR, Miller FD. Migrating Interneurons Secrete Fractalkine to Promote Oligodendrocyte Formation in the Developing Mammalian Brain. Neuron. 94: 500-516.e9. PMID 28472653 DOI: 10.1016/j.neuron.2017.04.018  1
2016 Yang G, Cancino GI, Zahr SK, Guskjolen A, Voronova A, Gallagher D, Frankland PW, Kaplan DR, Miller FD. A Glo1-Methylglyoxal Pathway that Is Perturbed in Maternal Diabetes Regulates Embryonic and Adult Neural Stem Cell Pools in Murine Offspring. Cell Reports. 17: 1022-1036. PMID 27760310 DOI: 10.1016/j.celrep.2016.09.067  1
2016 Yuzwa SA, Yang G, Borrett MJ, Clarke G, Cancino GI, Zahr SK, Zandstra PW, Kaplan DR, Miller FD. Proneurogenic Ligands Defined by Modeling Developing Cortex Growth Factor Communication Networks. Neuron. PMID 27545711 DOI: 10.1016/j.neuron.2016.07.037  1
2016 Grinshtein N, Rioseco CC, Marcellus R, Uehling D, Aman A, Lun X, Muto O, Podmore L, Lever J, Shen Y, Blough MD, Cairncross GJ, Robbins SM, Jones SJ, Marra MA, ... ... Kaplan DR, et al. Small molecule epigenetic screen identifies novel EZH2 and HDAC inhibitors that target glioblastoma brain tumor-initiating cells. Oncotarget. PMID 27449082 DOI: 10.18632/oncotarget.10661  0.32
2016 Johnston AP, Yuzwa SA, Carr MJ, Mahmud N, Storer MA, Krause MP, Jones K, Paul S, Kaplan DR, Miller FD. Dedifferentiated Schwann Cell Precursors Secreting Paracrine Factors Are Required for Regeneration of the Mammalian Digit Tip. Cell Stem Cell. PMID 27376984 DOI: 10.1016/j.stem.2016.06.002  1
2015 Zander MA, Burns SE, Yang G, Kaplan DR, Miller FD. REMOVED: Snail coordinately regulates downstream pathways to control multiple aspects of mammalian neural precursor development. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 47: 103. PMID 29887047 DOI: 10.1016/j.ijdevneu.2015.04.281  1
2015 Naska S, Yuzwa SA, Johnston AP, Paul S, Smith KM, Paris M, Sefton MV, Datti A, Miller FD, Kaplan DR. Identification of Drugs that Regulate Dermal Stem Cells and Enhance Skin Repair. Stem Cell Reports. PMID 26724904 DOI: 10.1016/j.stemcr.2015.12.002  1
2015 Fatt M, Hsu K, He L, Wondisford F, Miller FD, Kaplan DR, Wang J. Metformin Acts on Two Different Molecular Pathways to Enhance Adult Neural Precursor Proliferation/Self-Renewal and Differentiation. Stem Cell Reports. 5: 988-95. PMID 26677765 DOI: 10.1016/j.stemcr.2015.10.014  1
2015 Amadei G, Zander MA, Yang G, Dumelie JG, Vessey JP, Lipshitz HD, Smibert CA, Kaplan DR, Miller FD. A Smaug2-Based Translational Repression Complex Determines the Balance between Precursor Maintenance versus Differentiation during Mammalian Neurogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 15666-81. PMID 26609159 DOI: 10.1523/JNEUROSCI.2172-15.2015  1
2015 Zander MA, Burns SE, Yang G, Kaplan DR, Miller FD. Snail coordinately regulates downstream pathways to control multiple aspects of mammalian neural precursor development. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 47: 103. PMID 26531603 DOI: 10.1016/j.ijdevneu.2015.04.281  1
2015 Guang Y, Kaplan DR, Miller FD. The translational regulators eIF4E and 4E-T form a repressive protein:mRNA complex that determines neural stem cell self-renewal versus differentiation. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 47: 15. PMID 26531373 DOI: 10.1016/j.ijdevneu.2015.04.050  1
2015 Fatt MP, Cancino GI, Miller FD, Kaplan DR. p63 and p73 coordinate p53 function to determine the balance between survival, cell death and senescence in adult neural precursor cells. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 47: 13. PMID 26531369 DOI: 10.1016/j.ijdevneu.2015.04.045  1
2015 Cancino GI, Fatt MP, Miller FD, Kaplan DR. Conditional ablation of p63 indicates that it is essential for embryonic development of the central nervous system. Cell Cycle (Georgetown, Tex.). 14: 3270-81. PMID 26359534 DOI: 10.1080/15384101.2015.1087618  1
2015 Gallagher D, Voronova A, Zander MA, Cancino GI, Bramall A, Krause MP, Abad C, Tekin M, Neilsen PM, Callen DF, Scherer SW, Keller GM, Kaplan DR, Walz K, Miller FD. Ankrd11 is a chromatin regulator involved in autism that is essential for neural development. Developmental Cell. 32: 31-42. PMID 25556659 DOI: 10.1016/j.devcel.2014.11.031  1
2015 Lau ST, Hansford LM, Chan WK, Chan GC, Wan TS, Wong KK, Kaplan DR, Tam PK, Ngan ES. Prokineticin signaling is required for the maintenance of a de novo population of c-KIT⁺ cells to sustain neuroblastoma progression. Oncogene. 34: 1019-34. PMID 24632619 DOI: 10.1038/onc.2014.24  1
2015 Voronova A, Gallagher D, Zander M, Cancino G, Bramall A, Krause MP, Abad C, Tekin M, Neilsen PM, Callen DF, Scherer SW, Keller GM, Kaplan DR, Walz K, Miller FD. Ankrd11 is a chromatin regulator involved in autism that is essential for neural development Springerplus. 4: 1-32. DOI: 10.1186/2193-1801-4-S1-L28  1
2015 Pesaresi M, Soon-Shiong R, French L, D.R. Kaplan, Miller FD, Paus T. Axon diameter and axonal transport: In vivo and in vitro effects of androgens Neuroimage. 115: 191-201. DOI: 10.1016/j.neuroimage.2015.04.048  0.52
2014 Yang G, Smibert CA, Kaplan DR, Miller FD. An eIF4E1/4E-T complex determines the genesis of neurons from precursors by translationally repressing a proneurogenic transcription program. Neuron. 84: 723-39. PMID 25456498 DOI: 10.1016/j.neuron.2014.10.022  1
2014 Chavali PL, Saini RK, Zhai Q, Vizlin-Hodzic D, Venkatabalasubramanian S, Hayashi A, Johansson E, Zeng ZJ, Mohlin S, Påhlman S, Hansford L, Kaplan DR, Funa K. TLX activates MMP-2, promotes self-renewal of tumor spheres in neuroblastoma and correlates with poor patient survival. Cell Death & Disease. 5: e1502. PMID 25356871 DOI: 10.1038/cddis.2014.449  1
2014 Zander MA, Cancino GI, Gridley T, Kaplan DR, Miller FD. The Snail transcription factor regulates the numbers of neural precursor cells and newborn neurons throughout mammalian life. Plos One. 9: e104767. PMID 25136812 DOI: 10.1371/journal.pone.0104767  1
2014 Krause MP, Dworski S, Feinberg K, Jones K, Johnston AP, Paul S, Paris M, Peles E, Bagli D, Forrest CR, Kaplan DR, Miller FD. Direct genesis of functional rodent and human schwann cells from skin mesenchymal precursors. Stem Cell Reports. 3: 85-100. PMID 25068124 DOI: 10.1016/j.stemcr.2014.05.011  1
2014 Fatt MP, Cancino GI, Miller FD, Kaplan DR. p63 and p73 coordinate p53 function to determine the balance between survival, cell death, and senescence in adult neural precursor cells. Cell Death and Differentiation. 21: 1546-59. PMID 24809925 DOI: 10.1038/cdd.2014.61  1
2014 Zander MA, Burns SE, Yang G, Kaplan DR, Miller FD. Snail coordinately regulates downstream pathways to control multiple aspects of mammalian neural precursor development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 5164-75. PMID 24719096 DOI: 10.1523/JNEUROSCI.0370-14.2014  1
2014 Dixit R, Wilkinson G, Cancino GI, Shaker T, Adnani L, Li S, Dennis D, Kurrasch D, Chan JA, Olson EC, Kaplan DR, Zimmer C, Schuurmans C. Neurog1 and Neurog2 control two waves of neuronal differentiation in the piriform cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 539-53. PMID 24403153 DOI: 10.1523/JNEUROSCI.0614-13.2014  1
2014 Wolter JK, Wolter NE, Blanch A, Partridge T, Cheng L, Morgenstern DA, Podkowa M, Kaplan DR, Irwin MS. Anti-tumor activity of the beta-adrenergic receptor antagonist propranolol in neuroblastoma. Oncotarget. 5: 161-72. PMID 24389287  1
2014 Tsui D, Voronova A, Gallagher D, Kaplan DR, Miller FD, Wang J. CBP regulates the differentiation of interneurons from ventral forebrain neural precursors during murine development. Developmental Biology. 385: 230-41. PMID 24247009 DOI: 10.1016/j.ydbio.2013.11.005  1
2013 Haftchenary S, Luchman HA, Jouk AO, Veloso AJ, Page BD, Cheng XR, Dawson SS, Grinshtein N, Shahani VM, Kerman K, Kaplan DR, Griffin C, Aman AM, Al-Awar R, Weiss S, et al. Potent Targeting of the STAT3 Protein in Brain Cancer Stem Cells: A Promising Route for Treating Glioblastoma. Acs Medicinal Chemistry Letters. 4: 1102-7. PMID 24900612 DOI: 10.1021/ml4003138  1
2013 Gallagher D, Norman AA, Woodard CL, Yang G, Gauthier-Fisher A, Fujitani M, Vessey JP, Cancino GI, Sachewsky N, Woltjen K, Fatt MP, Morshead CM, Kaplan DR, Miller FD. Transient maternal IL-6 mediates long-lasting changes in neural stem cell pools by deregulating an endogenous self-renewal pathway. Cell Stem Cell. 13: 564-76. PMID 24209760 DOI: 10.1016/j.stem.2013.10.002  1
2013 Johnston AP, Naska S, Jones K, Jinno H, Kaplan DR, Miller FD. Sox2-mediated regulation of adult neural crest precursors and skin repair. Stem Cell Reports. 1: 38-45. PMID 24052940 DOI: 10.1016/j.stemcr.2013.04.004  1
2013 Cancino GI, Yiu AP, Fatt MP, Dugani CB, Flores ER, Frankland PW, Josselyn SA, Miller FD, Kaplan DR. p63 Regulates adult neural precursor and newly born neuron survival to control hippocampal-dependent Behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 12569-85. PMID 23904595 DOI: 10.1523/JNEUROSCI.1251-13.2013  1
2013 Vojvodic M, Hansford LM, Morozova O, Blakely KM, Taylor P, Fathers KE, Moffat J, Marra M, Smith KM, Moran MF, Kaplan DR. A phosphoproteomics approach to identify candidate kinase inhibitor pathway targets in lymphoma-like primary cell lines. Current Drug Discovery Technologies. 10: 283-304. PMID 23701117 DOI: 10.2174/15701638113109990001  1
2013 Tsui D, Vessey JP, Tomita H, Kaplan DR, Miller FD. FoxP2 regulates neurogenesis during embryonic cortical development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 244-58. PMID 23283338 DOI: 10.1523/JNEUROSCI.1665-12.2013  1
2013 Wang PY, Currier MA, Hansford L, Kaplan D, Chiocca EA, Uchida H, Goins WF, Cohen JB, Glorioso JC, van Kuppevelt TH, Mo X, Cripe TP. Expression of HSV-1 receptors in EBV-associated lymphoproliferative disease determines susceptibility to oncolytic HSV. Gene Therapy. 20: 761-9. PMID 23254370 DOI: 10.1038/gt.2012.93  1
2013 Cancino GI, Miller FD, Kaplan DR. p73 haploinsufficiency causes tau hyperphosphorylation and tau kinase dysregulation in mouse models of aging and Alzheimer's disease. Neurobiology of Aging. 34: 387-99. PMID 22592019 DOI: 10.1016/j.neurobiolaging.2012.04.010  1
2012 Vessey JP, Amadei G, Burns SE, Kiebler MA, Kaplan DR, Miller FD. An asymmetrically localized Staufen2-dependent RNA complex regulates maintenance of mammalian neural stem cells. Cell Stem Cell. 11: 517-28. PMID 22902294 DOI: 10.1016/j.stem.2012.06.010  1
2012 Wang J, Gallagher D, DeVito LM, Cancino GI, Tsui D, He L, Keller GM, Frankland PW, Kaplan DR, Miller FD. Metformin activates an atypical PKC-CBP pathway to promote neurogenesis and enhance spatial memory formation. Cell Stem Cell. 11: 23-35. PMID 22770240 DOI: 10.1016/j.stem.2012.03.016  1
2012 Miller FD, Kaplan DR. Mobilizing endogenous stem cells for repair and regeneration: are we there yet? Cell Stem Cell. 10: 650-2. PMID 22704501 DOI: 10.1016/j.stem.2012.05.004  1
2011 Chung J, Grant RI, Kaplan DR, Irwin MS. Special AT-rich binding protein-2 (SATB2) differentially affects disease-causing p63 mutant proteins. The Journal of Biological Chemistry. 286: 40671-80. PMID 21965674 DOI: 10.1074/jbc.M111.271189  1
2011 Grinshtein N, Datti A, Fujitani M, Uehling D, Prakesch M, Isaac M, Irwin MS, Wrana JL, Al-Awar R, Kaplan DR. Small molecule kinase inhibitor screen identifies polo-like kinase 1 as a target for neuroblastoma tumor-initiating cells. Cancer Research. 71: 1385-95. PMID 21303981 DOI: 10.1158/0008-5472.CAN-10-2484  1
2011 Antony JM, Paquin A, Nutt SL, Kaplan DR, Miller FD. Endogenous microglia regulate development of embryonic cortical precursor cells. Journal of Neuroscience Research. 89: 286-98. PMID 21259316 DOI: 10.1002/jnr.22533  1
2011 Castelo-Branco P, Zhang C, Lipman T, Fujitani M, Hansford L, Clarke I, Harley CB, Tressler R, Malkin D, Walker E, Kaplan DR, Dirks P, Tabori U. Neural tumor-initiating cells have distinct telomere maintenance and can be safely targeted for telomerase inhibition. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 111-21. PMID 21208905 DOI: 10.1158/1078-0432.CCR-10-2075  1
2010 Fujitani M, Cancino GI, Dugani CB, Weaver IC, Gauthier-Fisher A, Paquin A, Mak TW, Wojtowicz MJ, Miller FD, Kaplan DR. TAp73 acts via the bHLH Hey2 to promote long-term maintenance of neural precursors. Current Biology : Cb. 20: 2058-65. PMID 21074438 DOI: 10.1016/j.cub.2010.10.029  1
2010 Dugani CB, Paquin A, Kaplan DR, Miller FD. Coffin-Lowry syndrome: a role for RSK2 in mammalian neurogenesis. Developmental Biology. 347: 348-59. PMID 20832397 DOI: 10.1016/j.ydbio.2010.08.035  1
2010 Chung J, Lau J, Cheng LS, Grant RI, Robinson F, Ketela T, Reis PP, Roche O, Kamel-Reid S, Moffat J, Ohh M, Perez-Ordonez B, Kaplan DR, Irwin MS. SATB2 augments ΔNp63α in head and neck squamous cell carcinoma. Embo Reports. 11: 777-83. PMID 20829881 DOI: 10.1038/embor.2010.125  1
2010 Smith KM, Datti A, Fujitani M, Grinshtein N, Zhang L, Morozova O, Blakely KM, Rotenberg SA, Hansford LM, Miller FD, Yeger H, Irwin MS, Moffat J, Marra MA, Baruchel S, ... ... Kaplan DR, et al. Selective targeting of neuroblastoma tumour-initiating cells by compounds identified in stem cell-based small molecule screens. Embo Molecular Medicine. 2: 371-84. PMID 20721990 DOI: 10.1002/emmm.201000093  1
2010 Naska S, Lin DC, Miller FD, Kaplan DR. p75NTR is an obligate signaling receptor required for cues that cause sympathetic neuron growth cone collapse. Molecular and Cellular Neurosciences. 45: 108-20. PMID 20584617 DOI: 10.1016/j.mcn.2010.05.015  1
2010 Park KJ, Grosso CA, Aubert I, Kaplan DR, Miller FD. p75NTR-dependent, myelin-mediated axonal degeneration regulates neural connectivity in the adult brain. Nature Neuroscience. 13: 559-66. PMID 20348920 DOI: 10.1038/nn.2513  1
2010 Wilhelm MT, Rufini A, Wetzel MK, Tsuchihara K, Inoue S, Tomasini R, Itie-Youten A, Wakeham A, Arsenian-Henriksson M, Melino G, Kaplan DR, Miller FD, Mak TW. Isoform-specific p73 knockout mice reveal a novel role for delta Np73 in the DNA damage response pathway. Genes & Development. 24: 549-60. PMID 20194434 DOI: 10.1101/gad.1873910  1
2010 Wang J, Weaver IC, Gauthier-Fisher A, Wang H, He L, Yeomans J, Wondisford F, Kaplan DR, Miller FD. CBP histone acetyltransferase activity regulates embryonic neural differentiation in the normal and Rubinstein-Taybi syndrome brain. Developmental Cell. 18: 114-25. PMID 20152182 DOI: 10.1016/j.devcel.2009.10.023  1
2009 Pietras A, Hansford LM, Johnsson AS, Bridges E, Sjölund J, Gisselsson D, Rehn M, Beckman S, Noguera R, Navarro S, Cammenga J, Fredlund E, Kaplan DR, PÃ¥hlman S. HIF-2alpha maintains an undifferentiated state in neural crest-like human neuroblastoma tumor-initiating cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 16805-10. PMID 19805377 DOI: 10.1073/pnas.0904606106  1
2009 Harel L, Costa B, Tcherpakov M, Zapatka M, Oberthuer A, Hansford LM, Vojvodic M, Levy Z, Chen ZY, Lee FS, Avigad S, Yaniv I, Shi L, Eils R, Fischer M, ... ... Kaplan DR, et al. CCM2 mediates death signaling by the TrkA receptor tyrosine kinase. Neuron. 63: 585-91. PMID 19755102 DOI: 10.1016/j.neuron.2009.08.020  1
2009 Dugani CB, Paquin A, Fujitani M, Kaplan DR, Miller FD. p63 antagonizes p53 to promote the survival of embryonic neural precursor cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 6710-21. PMID 19458240 DOI: 10.1523/JNEUROSCI.5878-08.2009  1
2009 Gauthier-Fisher A, Lin DC, Greeve M, Kaplan DR, Rottapel R, Miller FD. Lfc and Tctex-1 regulate the genesis of neurons from cortical precursor cells. Nature Neuroscience. 12: 735-44. PMID 19448628 DOI: 10.1038/nn.2339  1
2009 Zhang L, Smith KM, Chong AL, Stempak D, Yeger H, Marrano P, Thorner PS, Irwin MS, Kaplan DR, Baruchel S. In vivo antitumor and antimetastatic activity of sunitinib in preclinical neuroblastoma mouse model. Neoplasia (New York, N.Y.). 11: 426-35. PMID 19412427 DOI: 10.1593/neo.09166  1
2009 Paquin A, Hordo C, Kaplan DR, Miller FD. Costello syndrome H-Ras alleles regulate cortical development. Developmental Biology. 330: 440-51. PMID 19371735 DOI: 10.1016/j.ydbio.2009.04.010  1
2009 Lavoie JF, Biernaskie JA, Chen Y, Bagli D, Alman B, Kaplan DR, Miller FD. Skin-derived precursors differentiate into skeletogenic cell types and contribute to bone repair. Stem Cells and Development. 18: 893-906. PMID 18834279 DOI: 10.1089/scd.2008.0260  1
2008 Tomasini R, Tsuchihara K, Wilhelm M, Fujitani M, Rufini A, Cheung CC, Khan F, Itie-Youten A, Wakeham A, Tsao MS, Iovanna JL, Squire J, Jurisica I, Kaplan D, Melino G, et al. TAp73 knockout shows genomic instability with infertility and tumor suppressor functions. Genes & Development. 22: 2677-91. PMID 18805989 DOI: 10.1101/gad.1695308  1
2008 Wetzel MK, Naska S, Laliberté CL, Rymar VV, Fujitani M, Biernaskie JA, Cole CJ, Lerch JP, Spring S, Wang SH, Frankland PW, Henkelman RM, Josselyn SA, Sadikot AF, Miller FD, ... Kaplan DR, et al. p73 regulates neurodegeneration and phospho-tau accumulation during aging and Alzheimer's disease. Neuron. 59: 708-21. PMID 18786355 DOI: 10.1016/j.neuron.2008.07.021  1
2008 Bisson N, Tremblay M, Robinson F, Kaplan DR, Trusko SP, Moss T. Mice lacking both mixed-lineage kinase genes Mlk1 and Mlk2 retain a wild type phenotype. Cell Cycle (Georgetown, Tex.). 7: 909-16. PMID 18414056 DOI: 10.4161/cc.7.7.5610  1
2008 Singh KK, Park KJ, Hong EJ, Kramer BM, Greenberg ME, Kaplan DR, Miller FD. Developmental axon pruning mediated by BDNF-p75NTR-dependent axon degeneration. Nature Neuroscience. 11: 649-58. PMID 18382462 DOI: 10.1038/nn.2114  1
2008 Taniguchi J, Fujitani M, Endo M, Kubo T, Fujitani M, Miller FD, Kaplan DR, Yamashita T. Rap1 is involved in the signal transduction of myelin-associated glycoprotein. Cell Death and Differentiation. 15: 408-19. PMID 18049479 DOI: 10.1038/sj.cdd.4402278  1
2007 Hansford LM, McKee AE, Zhang L, George RE, Gerstle JT, Thorner PS, Smith KM, Look AT, Yeger H, Miller FD, Irwin MS, Thiele CJ, Kaplan DR. Neuroblastoma cells isolated from bone marrow metastases contain a naturally enriched tumor-initiating cell. Cancer Research. 67: 11234-43. PMID 18056449 DOI: 10.1158/0008-5472.CAN-07-0718  1
2007 Bartkowska K, Paquin A, Gauthier AS, Kaplan DR, Miller FD. Trk signaling regulates neural precursor cell proliferation and differentiation during cortical development. Development (Cambridge, England). 134: 4369-80. PMID 18003743 DOI: 10.1242/dev.008227  1
2007 Kaplan DR, Miller FD. Developing with BDNF: a moving experience. Neuron. 55: 1-2. PMID 17610810 DOI: 10.1016/j.neuron.2007.06.025  1
2007 Gauthier AS, Furstoss O, Araki T, Chan R, Neel BG, Kaplan DR, Miller FD. Control of CNS cell-fate decisions by SHP-2 and its dysregulation in Noonan syndrome. Neuron. 54: 245-62. PMID 17442246 DOI: 10.1016/j.neuron.2007.03.027  1
2007 Quevedo C, Kaplan DR, Derry WB. AKT-1 regulates DNA-damage-induced germline apoptosis in C. elegans. Current Biology : Cb. 17: 286-92. PMID 17276923 DOI: 10.1016/j.cub.2006.12.038  1
2007 Miller FD, Kaplan DR. To die or not to die: neurons and p63. Cell Cycle (Georgetown, Tex.). 6: 312-7. PMID 17264677  1
2007 Lau L, Hansford LM, Cheng LS, Hang M, Baruchel S, Kaplan DR, Irwin MS. Cyclooxygenase inhibitors modulate the p53/HDM2 pathway and enhance chemotherapy-induced apoptosis in neuroblastoma. Oncogene. 26: 1920-31. PMID 16983334 DOI: 10.1038/sj.onc.1209981  1
2006 Naska S, Park KJ, Hannigan GE, Dedhar S, Miller FD, Kaplan DR. An essential role for the integrin-linked kinase-glycogen synthase kinase-3 beta pathway during dendrite initiation and growth. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 13344-56. PMID 17182785 DOI: 10.1523/JNEUROSCI.4462-06.2006  1
2006 Lin DC, Quevedo C, Brewer NE, Bell A, Testa JR, Grimes ML, Miller FD, Kaplan DR. APPL1 associates with TrkA and GIPC1 and is required for nerve growth factor-mediated signal transduction. Molecular and Cellular Biology. 26: 8928-41. PMID 17000777 DOI: 10.1128/MCB.00228-06  1
2006 Volosin M, Song W, Almeida RD, Kaplan DR, Hempstead BL, Friedman WJ. Interaction of survival and death signaling in basal forebrain neurons: roles of neurotrophins and proneurotrophins. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 7756-66. PMID 16855103 DOI: 10.1523/JNEUROSCI.1560-06.2006  1
2006 Hibbert AP, Kramer BM, Miller FD, Kaplan DR. The localization, trafficking and retrograde transport of BDNF bound to p75NTR in sympathetic neurons. Molecular and Cellular Neurosciences. 32: 387-402. PMID 16843677 DOI: 10.1016/j.mcn.2006.06.001  1
2006 Jacobs WB, Kaplan DR, Miller FD. The p53 family in nervous system development and disease. Journal of Neurochemistry. 97: 1571-84. PMID 16805769 DOI: 10.1111/j.1471-4159.2006.03980.x  1
2006 Kaplan DR, Miller FD. When a motor goes bad: a kinesin regulates neuronal survival. Cell. 125: 224-6. PMID 16630809 DOI: 10.1016/j.cell.2006.03.031  1
2006 Karim F, Hu HJ, Adwanikar H, Kaplan D, Gereau RW. Impaired inflammatory pain and thermal hyperalgesia in mice expressing neuron-specific dominant negative mitogen activated protein kinase kinase (MEK). Molecular Pain. 2: 2. PMID 16412244 DOI: 10.1186/1744-8069-2-2  1
2005 Jacobs WB, Govoni G, Ho D, Atwal JK, Barnabe-Heider F, Keyes WM, Mills AA, Miller FD, Kaplan DR. p63 is an essential proapoptotic protein during neural development. Neuron. 48: 743-56. PMID 16337913 DOI: 10.1016/j.neuron.2005.10.027  1
2005 Barnabé-Heider F, Wasylnka JA, Fernandes KJ, Porsche C, Sendtner M, Kaplan DR, Miller FD. Evidence that embryonic neurons regulate the onset of cortical gliogenesis via cardiotrophin-1. Neuron. 48: 253-65. PMID 16242406 DOI: 10.1016/j.neuron.2005.08.037  1
2005 Lavoie JF, Lesauteur L, Kohn J, Wong J, Furtoss O, Thiele CJ, Miller FD, Kaplan DR. TrkA induces apoptosis of neuroblastoma cells and does so via a p53-dependent mechanism. The Journal of Biological Chemistry. 280: 29199-207. PMID 15961390 DOI: 10.1074/jbc.M502364200  1
2005 Subramaniam S, Shahani N, Strelau J, Laliberté C, Brandt R, Kaplan D, Unsicker K. Insulin-like growth factor 1 inhibits extracellular signal-regulated kinase to promote neuronal survival via the phosphatidylinositol 3-kinase/protein kinase A/c-Raf pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2838-52. PMID 15772344 DOI: 10.1523/JNEUROSCI.5060-04.2005  1
2004 Fernandes KJ, McKenzie IA, Mill P, Smith KM, Akhavan M, Barnabé-Heider F, Biernaskie J, Junek A, Kobayashi NR, Toma JG, Kaplan DR, Labosky PA, Rafuse V, Hui CC, Miller FD. A dermal niche for multipotent adult skin-derived precursor cells. Nature Cell Biology. 6: 1082-93. PMID 15517002 DOI: 10.1038/ncb1181  1
2004 Walsh GS, Orike N, Kaplan DR, Miller FD. The invulnerability of adult neurons: a critical role for p73. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 9638-47. PMID 15509751 DOI: 10.1523/JNEUROSCI.1299-04.2004  1
2004 Lee AF, Ho DK, Zanassi P, Walsh GS, Kaplan DR, Miller FD. Evidence that DeltaNp73 promotes neuronal survival by p53-dependent and p53-independent mechanisms. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 9174-84. PMID 15483136 DOI: 10.1523/JNEUROSCI.1588-04.2004  1
2004 Subramaniam S, Zirrgiebel U, von Bohlen Und Halbach O, Strelau J, Laliberté C, Kaplan DR, Unsicker K. ERK activation promotes neuronal degeneration predominantly through plasma membrane damage and independently of caspase-3. The Journal of Cell Biology. 165: 357-69. PMID 15123736 DOI: 10.1083/jcb.200403028  1
2004 Shalin SC, Zirrgiebel U, Honsa KJ, Julien JP, Miller FD, Kaplan DR, Sweatt JD. Neuronal MEK is important for normal fear conditioning in mice. Journal of Neuroscience Research. 75: 760-70. PMID 14994337 DOI: 10.1002/jnr.20052  1
2004 Kaplan DR, Miller FD. Neurobiology: a move to sort life from death. Nature. 427: 798-9. PMID 14985746 DOI: 10.1038/427798a  1
2003 Marsh HN, Dubreuil CI, Quevedo C, Lee A, Majdan M, Walsh GS, Hausdorff S, Said FA, Zoueva O, Kozlowski M, Siminovitch K, Neel BG, Miller FD, Kaplan DR. SHP-1 negatively regulates neuronal survival by functioning as a TrkA phosphatase. The Journal of Cell Biology. 163: 999-1010. PMID 14662744 DOI: 10.1083/jcb.200309036  1
2003 Atwal JK, Singh KK, Tessier-Lavigne M, Miller FD, Kaplan DR. Semaphorin 3F antagonizes neurotrophin-induced phosphatidylinositol 3-kinase and mitogen-activated protein kinase kinase signaling: a mechanism for growth cone collapse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7602-9. PMID 12930799  1
2003 Miller FD, Kaplan DR. Signaling mechanisms underlying dendrite formation. Current Opinion in Neurobiology. 13: 391-8. PMID 12850225 DOI: 10.1016/S0959-4388(03)00072-2  1
2003 Kaplan DR, Miller FD. Axon growth inhibition: signals from the p75 neurotrophin receptor. Nature Neuroscience. 6: 435-6. PMID 12715005 DOI: 10.1038/nn0503-435  1
2003 Nguyen MD, Boudreau M, Kriz J, Couillard-Després S, Kaplan DR, Julien JP. Cell cycle regulators in the neuronal death pathway of amyotrophic lateral sclerosis caused by mutant superoxide dismutase 1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 2131-40. PMID 12657672  1
2002 Makris C, Voisin L, Giasson E, Tudan C, Kaplan DR, Meloche S. The Rb-family protein p107 inhibits translation by a PDK1-dependent mechanism. Oncogene. 21: 7891-6. PMID 12420226 DOI: 10.1038/sj.onc.1205964  1
2002 Wartiovaara K, Barnabe-Heider F, Miller FD, Kaplan DR. N-myc promotes survival and induces S-phase entry of postmitotic sympathetic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 815-24. PMID 11826111  1
2001 Miller FD, Kaplan DR. On Trk for retrograde signaling. Neuron. 32: 767-70. PMID 11738023 DOI: 10.1016/S0896-6273(01)00529-3  1
2001 Toma JG, Akhavan M, Fernandes KJ, Barnabé-Heider F, Sadikot A, Kaplan DR, Miller FD. Isolation of multipotent adult stem cells from the dermis of mammalian skin. Nature Cell Biology. 3: 778-84. PMID 11533656 DOI: 10.1038/ncb0901-778  1
2001 Miller FD, Kaplan DR. Neurotrophin signalling pathways regulating neuronal apoptosis. Cellular and Molecular Life Sciences : Cmls. 58: 1045-53. PMID 11529497 DOI: 10.1007/PL00000919  1
2001 Esposito D, Patel P, Stephens RM, Perez P, Chao MV, Kaplan DR, Hempstead BL. The cytoplasmic and transmembrane domains of the p75 and Trk A receptors regulate high affinity binding to nerve growth factor. The Journal of Biological Chemistry. 276: 32687-95. PMID 11435417 DOI: 10.1074/jbc.M011674200  1
2001 Kaplan DR, Cooper E. PI-3 kinase and IP3: partners in NT3-induced synaptic transmission. Nature Neuroscience. 4: 5-7. PMID 11135633 DOI: 10.1038/82897  1
2000 Atwal JK, Massie B, Miller FD, Kaplan DR. The TrkB-Shc site signals neuronal survival and local axon growth via MEK and P13-kinase. Neuron. 27: 265-77. PMID 10985347  1
2000 Pozniak CD, Radinovic S, Yang A, McKeon F, Kaplan DR, Miller FD. An anti-apoptotic role for the p53 family member, p73, during developmental neuron death. Science (New York, N.Y.). 289: 304-6. PMID 10894779 DOI: 10.1126/science.289.5477.304  1
2000 Kaplan DR, Miller FD. Neurotrophin signal transduction in the nervous system. Current Opinion in Neurobiology. 10: 381-91. PMID 10851172 DOI: 10.1016/S0959-4388(00)00092-1  1
2000 Mamounas LA, Altar CA, Blue ME, Kaplan DR, Tessarollo L, Lyons WE. BDNF promotes the regenerative sprouting, but not survival, of injured serotonergic axons in the adult rat brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 771-82. PMID 10632606  1
1999 Korhonen JM, Saïd FA, Wong AJ, Kaplan DR. Gab1 mediates neurite outgrowth, DNA synthesis, and survival in PC12 cells. The Journal of Biological Chemistry. 274: 37307-14. PMID 10601297 DOI: 10.1074/jbc.274.52.37307  1
1999 Ashcroft M, Stephens RM, Hallberg B, Downward J, Kaplan DR. The selective and inducible activation of endogenous PI 3-kinase in PC12 cells results in efficient NGF-mediated survival but defective neurite outgrowth Oncogene. 18: 4586-4597. PMID 10467403 DOI: 10.1038/sj.onc.1202814  1
1998 Miller FD, Kaplan DR. Life and death decisions: A biological role for the p75 neurotrophin receptor Cell Death and Differentiation. 5: 343-345. PMID 10200482 DOI: 10.1038/sj.cdd.4400385  1
1998 Kaplan DR. Studying signal transduction in neuronal cells: The Trk/NGF system Progress in Brain Research. 117: 35-46. PMID 9932398 DOI: 10.1016/S0079-6123(08)64005-4  1
1998 Aloyz RS, Bamji SX, Pozniak CD, Toma JG, Atwal J, Kaplan DR, Miller FD. p53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors. The Journal of Cell Biology. 143: 1691-703. PMID 9852160 DOI: 10.1083/jcb.143.6.1691  1
1998 Hallberg B, Ashcroft M, Loeb DM, Kaplan DR, Downward J. Nerve growth factor induced stimulation of Ras requires Trk interaction with Shc but does not involve phosphoinositide 3-OH kinase Oncogene. 17: 691-697. PMID 9715270 DOI: 10.1038/sj.onc.1201980  1
1998 Tajima Y, Molina RP, Rorke LB, Kaplan DR, Radeke M, Feinstein SC, Lee VMY, Trojanowski JQ. Neurotrophins and neuronal versus glial differentiation in medulloblastomas and other pediatric brain tumors Acta Neuropathologica. 95: 325-332. PMID 9560008 DOI: 10.1007/s004010050806  1
1998 Friedman WJ, Black IB, Kaplan DR. Distribution of the neurotrophins brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4/5 in the postnatal rat brain: an immunocytochemical study. Neuroscience. 84: 101-14. PMID 9522366 DOI: 10.1016/S0306-4522(97)00526-5  1
1998 Wolf DE, McKinnon-Thompson C, Daou MC, Stephens RM, Kaplan DR, Ross AH. Mobility of TrkA is regulated by phosphorylation and interactions with the low-affinity NGF receptor. Biochemistry. 37: 3178-86. PMID 9485472 DOI: 10.1021/bi9719253  1
1997 Fryer RH, Kaplan DR, Kromer LF. Truncated trkB receptors on nonneuronal cells inhibit BDNF-induced neurite outgrowth in vitro. Experimental Neurology. 148: 616-27. PMID 9417837 DOI: 10.1006/exnr.1997.6699  1
1997 Songyang Z, Baltimore D, Cantley LC, Kaplan DR, Franke TF. Interleukin 3-dependent survival by the Akt protein kinase Proceedings of the National Academy of Sciences of the United States of America. 94: 11345-11350. PMID 9326612 DOI: 10.1073/pnas.94.21.11345  1
1997 Knusel B, Gao H, Okazaki T, Yoshida T, Mori N, Hefti F, Kaplan DR. Ligand-induced down-regulation of Trk messenger RNA, protein and tyrosine phosphorylation in rat cortical neurons. Neuroscience. 78: 851-62. PMID 9153663 DOI: 10.1016/S0306-4522(96)00616-1  1
1997 Cunningham ME, Stephens RM, Kaplan DR, Greene LA. Autophosphorylation of activation loop tyrosines regulates signaling by the TRK nerve growth factor receptor. The Journal of Biological Chemistry. 272: 10957-67. PMID 9099755 DOI: 10.1074/jbc.272.16.10957  1
1997 Franke TF, Kaplan DR, Cantley LC. PI3K: Downstream AKTion blocks apoptosis Cell. 88: 435-437. PMID 9038334 DOI: 10.1016/S0092-8674(00)81883-8  1
1997 Franke TF, Kaplan DR, Cantley LC, Toker A. Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate Science. 275: 665-668. PMID 9005852 DOI: 10.1126/science.275.5300.665  1
1997 Dudek H, Datta SR, Franke TF, Birnbaum MJ, Yao R, Cooper GM, Segal RA, Kaplan DR, Greenberg ME. Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science (New York, N.Y.). 275: 661-5. PMID 9005851 DOI: 10.1126/science.275.5300.661  1
1996 Fryer RH, Kaplan DR, Feinstein SC, Radeke MJ, Grayson DR, Kromer LF. Developmental and mature expression of full-length and truncated TrkB receptors in the rat forebrain. The Journal of Comparative Neurology. 374: 21-40. PMID 8891944 DOI: 10.1002/(SICI)1096-9861(19961007)374:1<21::AID-CNE2>3.0.CO;2-P  1
1996 Sterneck E, Kaplan DR, Johnson PF. Interleukin-6 induces expression of peripherin and cooperates with Trk receptor signaling to promote neuronal differentiation in PC12 cells Journal of Neurochemistry. 67: 1365-1374. PMID 8858917 DOI: 10.1046/j.1471-4159.1996.67041365.x  1
1996 Segal RA, Bhattacharyya A, Rua LA, Alberta JA, Stephens RM, Kaplan DR, Stiles CD. Differential utilization of Trk autophosphorylation sites. The Journal of Biological Chemistry. 271: 20175-81. PMID 8702742 DOI: 10.1074/jbc.271.33.20175  1
1996 Knusel B, Kaplan DR, Hefti F. Intraparenchymal NGF injections in adult and aged rats induce long-lasting Trk tyrosine phosphorylation. Experimental Neurology. 139: 121-30. PMID 8635559 DOI: 10.1006/exnr.1996.0087  1
1996 Tsoulfas P, Stephens RM, Kaplan DR, Parada LF. TrkC isoforms with inserts in the kinase domain show impaired signaling responses. The Journal of Biological Chemistry. 271: 5691-7. PMID 8621434 DOI: 10.1074/jbc.271.10.5691  1
1996 Angeles TS, Steffler C, Bartlett BA, Hudkins RL, Stephens RM, Kaplan DR, Dionne CA. Enzyme-linked immunosorbent assay for trkA tyrosine kinase activity Analytical Biochemistry. 236: 49-55. PMID 8619495 DOI: 10.1006/abio.1996.0130  1
1996 Ross AH, Daou MC, McKinnon CA, Condon PJ, Lachyankar MB, Stephens RM, Kaplan DR, Wolf DE. The neurotrophin receptor, gp75, forms a complex with the receptor tyrosine kinase TrkA. The Journal of Cell Biology. 132: 945-53. PMID 8603925 DOI: 10.1083/jcb.132.5.945  1
1995 Greene LA, Kaplan DR. Early events in neurotrophin signalling via Trk and p75 receptors Current Opinion in Neurobiology. 5: 579-587. PMID 8580709 DOI: 10.1016/0959-4388(95)80062-X  1
1995 Datta K, Franke TF, Chan TO, Makris A, Yang SI, Kaplan DR, Morrison DK, Golemis EA, Tsichlis PN. AH/PH domain-mediated interaction between Akt molecules and its potential role in Akt regulation Molecular and Cellular Biology. 15: 2304-2310. PMID 7891724  1
1995 Melamed I, Turner CE, Aktories K, Kaplan DR, Gelfand EW. Nerve growth factor triggers microfilament assembly and paxillin phosphorylation in human B lymphocytes Journal of Experimental Medicine. 181: 1071-1079. PMID 7869029 DOI: 10.1084/jem.181.3.1071  1
1995 Ferrari G, Anderson BL, Stephens RM, Kaplan DR, Greene LA. Prevention of apoptotic neuronal death by GM1 ganglioside. Involvement of Trk neurotrophin receptors. The Journal of Biological Chemistry. 270: 3074-80. PMID 7852388 DOI: 10.1074/jbc.270.7.3074  1
1995 Wolf DE, McKinnon CA, Daou MC, Stephens RM, Kaplan DR, Ross AH. Interaction with TrkA immobilizes gp75 in the high affinity nerve growth factor receptor complex. The Journal of Biological Chemistry. 270: 2133-8. PMID 7836442 DOI: 10.1074/jbc.270.5.2133  1
1995 Franke TF, Yang SI, Chan TO, Datta K, Kazlauskas A, Morrison DK, Kaplan DR, Tsichlis PN. The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell. 81: 727-36. PMID 7774014 DOI: 10.1016/0092-8674(95)90534-0  1
1995 Peng X, Greene LA, Kaplan DR, Stephens RM. Deletion of a conserved juxtamembrane sequence in Trk abolishes NGF-promoted neuritogenesis Neuron. 15: 395-406. PMID 7646892 DOI: 10.1016/0896-6273(95)90043-8  1
1995 Vambutas V, Kaplan DR, Sells MA, Chernoff J. Nerve growth factor stimulates tyrosine phosphorylation and activation of Src homology-containing protein-tyrosine phosphatase 1 in PC12 cells Journal of Biological Chemistry. 270: 25629-25633. PMID 7592737 DOI: 10.1074/jbc.270.43.25629  1
1995 Lucarelli E, Kaplan DR, Thiele CJ. Selective regulation of TrkA and TrkB receptors by retinoic acid and interferon-γ in human neuroblastoma cell lines Journal of Biological Chemistry. 270: 24725-24731. PMID 7559588 DOI: 10.1074/jbc.270.42.24725  1
1995 Ehlers MD, Kaplan DR, Price DL, Koliatsos VE. NGF-stimulated retrograde transport of trkA in the mammalian nervous system. The Journal of Cell Biology. 130: 149-56. PMID 7540615 DOI: 10.1083/jcb.130.1.149  1
1994 Stephens RM, Loeb DM, Copeland TD, Pawson T, Greene LA, Kaplan DR. Trk receptors use redundant signal transduction pathways involving SHC and PLC-γ1 to mediate NGF responses Neuron. 12: 691-705. PMID 8155326 DOI: 10.1016/0896-6273(94)90223-2  1
1994 Allendoerfer KL, Cabelli RJ, Escandón E, Kaplan DR, Nikolics K, Shatz CJ. Regulation of neurotrophin receptors during the maturation of the mammalian visual system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 1795-811. PMID 8126572  1
1994 Kaplan DR, Stephens RM. Neurotrophin signal transduction by the Trk receptor Journal of Neurobiology. 25: 1404-1417. PMID 7852994 DOI: 10.1002/neu.480251108  1
1993 Widmer HR, Kaplan DR, Rabin SJ, Beck KD, Hefti F, Knüsel B. Rapid phosphorylation of phospholipase C gamma 1 by brain-derived neurotrophic factor and neurotrophin-3 in cultures of embryonic rat cortical neurons. Journal of Neurochemistry. 60: 2111-23. PMID 8492120  1
1993 Kaplan DR, Matsumoto K, Lucarelli E, Thielet CJ. Induction of TrkB by retinoic acid mediates biologic responsiveness to BDNF and differentiation of human neuroblastoma cells Neuron. 11: 321-331. PMID 8394722 DOI: 10.1016/0896-6273(93)90187-V  1
1993 Rabin SJ, Cleghon V, Kaplan DR. SNT, a differentiation-specific target of neurotrophic factor-induced tyrosine kinase activity in neurons and PC12 cells Molecular and Cellular Biology. 13: 2203-2213. PMID 7681142 DOI: 10.1128/MCB.13.4.2203  1
1992 Knüsel B, Kaplan DR, Winslow JW, Rosenthal A, Burton LE, Beck KD, Rabin S, Nikolics K, Hefti F. K-252b selectively potentiates cellular actions and trk tyrosine phosphorylation mediated by neurotrophin-3. Journal of Neurochemistry. 59: 715-22. PMID 1629741 DOI: 10.1111/j.1471-4159.1992.tb09427.x  1
1992 Stephens RM, Sithanandam G, Copeland TD, Kaplan DR, Rapp UR, Morrison DK. 95-Kilodalton B-Raf Serine/Threonine Kinase: Identification of the Protein and Its Major Autophosphorylation Site Molecular and Cellular Biology. 12: 3733-3742. PMID 1508179 DOI: 10.1128/MCB.12.9.3733  1
1992 Knüsel B, Rabin S, Widmer HR, Hefti F, Kaplan DR. Neurotrophin-induced trk receptor phosphorylation and cholinergic neuron response in primary cultures of embryonic rat brain neurons. Neuroreport. 3: 885-8. PMID 1421094  1
1992 Kaplan DR, Perkins A, Morrison DK. Signal transduction by receptor tyrosine kinases Cancer Treatment and Research. 63: 265-279. PMID 1363361 DOI: 10.1007/978-1-4615-3088-6_13  1
1991 Hempstead BL, Martin-Zanca D, Kaplan DR, Parada LF, Chao MV. High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor. Nature. 350: 678-83. PMID 1850821 DOI: 10.1038/350678a0  1
1991 Kaplan DR, Hempstead BL, Martin-Zanca D, Chao MV, Parada LF. The trk proto-oncogene product: a signal transducing receptor for nerve growth factor. Science (New York, N.Y.). 252: 554-8. PMID 1850549  1
1991 Vetter ML, Martin-Zanca D, Parada LF, Bishop JM, Kaplan DR. Nerve growth factor rapidly stimulates tyrosine phosphorylation of phospholipase C-gamma 1 by a kinase activity associated with the product of the trk protooncogene. Proceedings of the National Academy of Sciences of the United States of America. 88: 5650-4. PMID 1712104  1
1991 Escobedo JA, Kaplan DR, Kavanaugh WM, Turck CW, Williams LT. A Phosphatidylinositol-3 Kinase Binds to Platelet-Derived Growth Factor Receptors through a Specific Receptor Sequence Containing Phosphotyrosine Molecular and Cellular Biology. 11: 1125-1132. PMID 1703628  1
1990 Kaplan DR, Morrison DK, Wong G, McCormick F, Williams LT. PDGF β-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex Cell. 61: 125-133. PMID 2156626 DOI: 10.1016/0092-8674(90)90220-9  1
1990 Morrison DK, Kaplan DR, Rhee SG, Williams LT. Platelet-derived growth factor (PDGF)-dependent association of phospholipase C-γ with the PDGF receptor signaling complex Molecular and Cellular Biology. 10: 2359-2366. PMID 1691440  1
1989 Hall DJ, Jones SD, Kaplan DR, Whitman M, Rollins BJ, Stiles CD. Evidence for a novel signal transduction pathway activated by platelet-derived growth factor and by double-stranded RNA. Molecular and Cellular Biology. 9: 1705-13. PMID 2542776 DOI: 10.1128/MCB.9.4.1705  1
1989 Morrison DK, Kaplan DR, Escobedo JA, Rapp UR, Roberts TM, Williams LT. Direct activation of the serine/threonine kinase activity of raf-1 through tyrosine phosphorylation by the PDGF β-receptor Cell. 58: 649-657. PMID 2475255 DOI: 10.1016/0092-8674(89)90100-1  1
1989 Kaplan DR, Pallas DC, Morgan W, Schaffhausen B, Roberts TM. Mechanisms of transformation by polyoma virus middle T antigen Bba - Reviews On Cancer. 948: 345-364. PMID 2465782 DOI: 10.1016/0304-419X(89)90006-1  1
1988 Pallas DC, Cherington V, Morgan W, DeAnda J, Kaplan D, Schaffhausen B, Roberts TM. Cellular proteins that associate with the middle and small T antigens of polyomavirus Journal of Virology. 62: 3934-3940. PMID 2845116  1
1988 Morgan WC, Kaplan DR, Pallas DC, Roberts TM. Recombinant retroviruses that transduce middle T antigen cDNAs derived from polyomavirus mutants: Separation of focus formation and soft-agar growth in transformation assays and correlations with kinase activities in vitro Journal of Virology. 62: 3407-3414. PMID 2841493  1
1987 Kaplan DR, Whitman M, Schaffhausen B, Pallas DC, White M, Cantley L, Roberts TM. Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity Cell. 50: 1021-1029. PMID 2441878 DOI: 10.1016/0092-8674(87)90168-1  1
1986 Piwnica-Worms H, Kaplan DR, Whitman M, Roberts TM. Retrovirus shuttle vector for study of kinase activities of pp60c-src synthesized in vitro and overproduced in vivo Molecular and Cellular Biology. 6: 2033-2040. PMID 2431288 DOI: 10.1128/MCB.6.6.2033  1
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