Darrell A. Henze - Publications

Pain & Migraine Research Merck Research Laboratories, Boston, MA, United States 
Neuroscience, Pain, TrkA, cannabinoids, sodium channels

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Solly K, Klein R, Rudd M, Holloway MK, Johnson EN, Henze D, Finley MF. High-Throughput Screen of GluK1 Receptor Identifies Selective Inhibitors with a Variety of Kinetic Profiles Using Fluorescence and Electrophysiology Assays. Journal of Biomolecular Screening. 20: 708-19. PMID 25700884 DOI: 10.1177/1087057115570580  1
2014 Stachel SJ, Sanders JM, Henze DA, Rudd MT, Su HP, Li Y, Nanda KK, Egbertson MS, Manley PJ, Jones KL, Brnardic EJ, Green A, Grobler JA, Hanney B, Leitl M, et al. Maximizing diversity from a kinase screen: identification of novel and selective pan-Trk inhibitors for chronic pain. Journal of Medicinal Chemistry. 57: 5800-16. PMID 24914455 DOI: 10.1021/jm5006429  1
2014 Nanda KK, Henze DA, Della Penna K, Desai R, Leitl M, Lemaire W, White RB, Yeh S, Brouillette JN, Hartman GD, Bilodeau MT, Trotter BW. Benzimidazole CB2 agonists: design, synthesis and SAR. Bioorganic & Medicinal Chemistry Letters. 24: 1218-21. PMID 24461289 DOI: 10.1016/j.bmcl.2013.12.068  1
2011 Trotter BW, Nanda KK, Burgey CS, Potteiger CM, Deng JZ, Green AI, Hartnett JC, Kett NR, Wu Z, Henze DA, Della Penna K, Desai R, Leitl MD, Lemaire W, White RB, et al. Imidazopyridine CB2 agonists: optimization of CB2/CB1 selectivity and implications for in vivo analgesic efficacy. Bioorganic & Medicinal Chemistry Letters. 21: 2354-8. PMID 21420860 DOI: 10.1016/j.bmcl.2011.02.082  1
2011 Manley PJ, Zartman A, Paone DV, Burgey CS, Henze DA, Della Penna K, Desai R, Leitl MD, Lemaire W, White RB, Yeh S, Urban MO, Kane SA, Hartman GD, Bilodeau MT, et al. Decahydroquinoline amides as highly selective CB2 agonists: role of selectivity on in vivo efficacy in a rodent model of analgesia. Bioorganic & Medicinal Chemistry Letters. 21: 2359-64. PMID 21420857 DOI: 10.1016/j.bmcl.2011.02.078  1
2011 Wolkenberg SE, Zhao Z, Mulhearn JJ, Harrison ST, Sanders JM, Cato MJ, Jovanovska A, Panigel J, Cook SP, Henze DA, Kane SA, Hartman GD, Barrow JC. High concentration electrophysiology-based fragment screen: discovery of novel acid-sensing ion channel 3 (ASIC3) inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 2646-9. PMID 21257308 DOI: 10.1016/j.bmcl.2010.12.115  1
2011 Nantermet PG, Henze DA. Recent Advances Toward Pain Therapeutics Annual Reports in Medicinal Chemistry. 46: 19-32. DOI: 10.1016/B978-0-12-386009-5.00025-4  1
2009 Henze DA. Challenges faced in choosing novel targets to treat chronic pain. Future Medicinal Chemistry. 1: 231-5. PMID 21425964 DOI: 10.4155/fmc.09.33  1
2008 Eid SR, Crown ED, Moore EL, Liang HA, Choong KC, Dima S, Henze DA, Kane SA, Urban MO. HC-030031, a TRPA1 selective antagonist, attenuates inflammatory- and neuropathy-induced mechanical hypersensitivity. Molecular Pain. 4: 48. PMID 18954467 DOI: 10.1186/1744-8069-4-48  1
2007 Henze DA, Buzsáki G. Hilar mossy cells: functional identification and activity in vivo. Progress in Brain Research. 163: 199-216. PMID 17765720 DOI: 10.1016/S0079-6123(07)63012-X  1
2007 Wittner L, Henze DA, Záborszky L, Buzsáki G. Three-dimensional reconstruction of the axon arbor of a CA3 pyramidal cell recorded and filled in vivo. Brain Structure & Function. 212: 75-83. PMID 17717699 DOI: 10.1007/s00429-007-0148-y  1
2007 Jinno S, Klausberger T, Marton LF, Dalezios Y, Roberts JD, Fuentealba P, Bushong EA, Henze D, Buzsáki G, Somogyi P. Neuronal diversity in GABAergic long-range projections from the hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 8790-804. PMID 17699661 DOI: 10.1523/JNEUROSCI.1847-07.2007  1
2007 Gold C, Henze DA, Koch C. Using extracellular action potential recordings to constrain compartmental models. Journal of Computational Neuroscience. 23: 39-58. PMID 17273940 DOI: 10.1007/s10827-006-0018-2  1
2006 Isomura Y, Sirota A, Ozen S, Montgomery S, Mizuseki K, Henze DA, Buzsáki G. Integration and segregation of activity in entorhinal-hippocampal subregions by neocortical slow oscillations. Neuron. 52: 871-82. PMID 17145507 DOI: 10.1016/j.neuron.2006.10.023  1
2006 Wittner L, Henze DA, Záborszky L, Buzsáki G. Hippocampal CA3 pyramidal cells selectively innervate aspiny interneurons. The European Journal of Neuroscience. 24: 1286-98. PMID 16987216 DOI: 10.1111/j.1460-9568.2006.04992.x  1
2006 Catalano SM, Dodson EC, Henze DA, Joyce JG, Krafft GA, Kinney GG. The role of amyloid-beta derived diffusible ligands (ADDLs) in Alzheimer's disease. Current Topics in Medicinal Chemistry. 6: 597-608. PMID 16712494 DOI: 10.2174/156802606776743066  1
2006 Gold C, Henze DA, Koch C, Buzsáki G. On the origin of the extracellular action potential waveform: A modeling study. Journal of Neurophysiology. 95: 3113-28. PMID 16467426 DOI: 10.1152/jn.00979.2005  1
2005 Schmitzer-Torbert N, Jackson J, Henze D, Harris K, Redish AD. Quantitative measures of cluster quality for use in extracellular recordings. Neuroscience. 131: 1-11. PMID 15680687 DOI: 10.1016/j.neuroscience.2004.09.066  1
2005 Wittmann M, Marino MJ, Henze DA, Seabrook GR, Conn PJ. Clozapine potentiation of N-methyl-D-aspartate receptor currents in the nucleus accumbens: role of NR2B and protein kinase A/Src kinases. The Journal of Pharmacology and Experimental Therapeutics. 313: 594-603. PMID 15659539 DOI: 10.1124/jpet.104.080200  1
2004 Buzsáki G, Geisler C, Henze DA, Wang XJ. Interneuron Diversity series: Circuit complexity and axon wiring economy of cortical interneurons. Trends in Neurosciences. 27: 186-93. PMID 15046877 DOI: 10.1016/j.tins.2004.02.007  1
2003 Csicsvari J, Henze DA, Jamieson B, Harris KD, Sirota A, Barthó P, Wise KD, Buzsáki G. Massively parallel recording of unit and local field potentials with silicon-based electrodes. Journal of Neurophysiology. 90: 1314-23. PMID 12904510 DOI: 10.1152/jn.00116.2003  1
2002 González-Burgos G, Kröner S, Krimer LS, Seamans JK, Urban NN, Henze DA, Lewis DA, Barrionuevo G. Dopamine modulation of neuronal function in the monkey prefrontal cortex. Physiology & Behavior. 77: 537-43. PMID 12526996 DOI: 10.1016/S0031-9384(02)00940-X  1
2002 Buzsáki G, Csicsvari J, Dragoi G, Harris K, Henze D, Hirase H. Homeostatic maintenance of neuronal excitability by burst discharges in vivo. Cerebral Cortex (New York, N.Y. : 1991). 12: 893-9. PMID 12183388  1
2002 Henze DA, Wittner L, Buzsáki G. Single granule cells reliably discharge targets in the hippocampal CA3 network in vivo. Nature Neuroscience. 5: 790-5. PMID 12118256 DOI: 10.1038/nn887  1
2002 Harris KD, Henze DA, Hirase H, Leinekugel X, Dragoi G, Czurkó A, Buzsáki G. Spike train dynamics predicts theta-related phase precession in hippocampal pyramidal cells. Nature. 417: 738-41. PMID 12066184 DOI: 10.1038/nature00808  1
2002 Urban NN, González-Burgos G, Henze DA, Lewis DA, Barrionuevo G. Selective reduction by dopamine of excitatory synaptic inputs to pyramidal neurons in primate prefrontal cortex. The Journal of Physiology. 539: 707-12. PMID 11897842 DOI: 10.1113/jphysiol.2001.015024  1
2002 Marshall L, Henze DA, Hirase H, Leinekugel X, Dragoi G, Buzsáki G. Hippocampal pyramidal cell-interneuron spike transmission is frequency dependent and responsible for place modulation of interneuron discharge. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: RC197. PMID 11784809  1
2002 Henze DA, McMahon DB, Harris KM, Barrionuevo G. Giant miniature EPSCs at the hippocampal mossy fiber to CA3 pyramidal cell synapse are monoquantal. Journal of Neurophysiology. 87: 15-29. PMID 11784726  1
2001 Harris KD, Hirase H, Leinekugel X, Henze DA, Buzsáki G. Temporal interaction between single spikes and complex spike bursts in hippocampal pyramidal cells. Neuron. 32: 141-9. PMID 11604145 DOI: 10.1016/S0896-6273(01)00447-0  1
2001 Urban NN, Henze DA, Barrionuevo G. Revisiting the role of the hippocampal mossy fiber synapse. Hippocampus. 11: 408-17. PMID 11530845 DOI: 10.1002/hipo.1055  1
2001 Henze DA, Buzsáki G. Action potential threshold of hippocampal pyramidal cells in vivo is increased by recent spiking activity. Neuroscience. 105: 121-30. PMID 11483306 DOI: 10.1016/S0306-4522(01)00167-1  1
2001 Papp E, Leinekugel X, Henze DA, Lee J, Buzsáki G. The apical shaft of CA1 pyramidal cells is under GABAergic interneuronal control. Neuroscience. 102: 715-21. PMID 11182239 DOI: 10.1016/S0306-4522(00)00584-4  1
2000 Henze DA, González-Burgos GR, Urban NN, Lewis DA, Barrionuevo G. Dopamine increases excitability of pyramidal neurons in primate prefrontal cortex. Journal of Neurophysiology. 84: 2799-809. PMID 11110810  1
2000 Harris KD, Henze DA, Csicsvari J, Hirase H, Buzsáki G. Accuracy of tetrode spike separation as determined by simultaneous intracellular and extracellular measurements. Journal of Neurophysiology. 84: 401-14. PMID 10899214  1
2000 Henze DA, Borhegyi Z, Csicsvari J, Mamiya A, Harris KD, Buzsáki G. Intracellular features predicted by extracellular recordings in the hippocampus in vivo. Journal of Neurophysiology. 84: 390-400. PMID 10899213  1
2000 Henze DA, Urban NN, Barrionuevo G. The multifarious hippocampal mossy fiber pathway: a review. Neuroscience. 98: 407-27. PMID 10869836 DOI: 10.1016/S0306-4522(00)00146-9  1
1999 Penttonen M, Nurminen N, Miettinen R, Sirviö J, Henze DA, Csicsvári J, Buzsáki G. Ultra-slow oscillation (0.025 Hz) triggers hippocampal afterdischarges in Wistar rats. Neuroscience. 94: 735-43. PMID 10579564 DOI: 10.1016/S0306-4522(99)00367-X  1
1999 King C, Henze DA, Leinekugel X, Buzsáki G. Hebbian modification of a hippocampal population pattern in the rat. The Journal of Physiology. 521: 159-67. PMID 10562342  1
1998 Urban NN, Henze DA, Barrionuevo G. Amplification of perforant-path EPSPs in CA3 pyramidal cells by LVA calcium and sodium channels. Journal of Neurophysiology. 80: 1558-61. PMID 9744960  1
1997 Henze DA, Urban NN, Barrionuevo G. Origin of the apparent asynchronous activity of hippocampal mossy fibers. Journal of Neurophysiology. 78: 24-30. PMID 9242257  1
1997 Henze DA, Card JP, Barrionuevo G, Ben-Ari Y. Large amplitude miniature excitatory postsynaptic currents in hippocampal CA3 pyramidal neurons are of mossy fiber origin. Journal of Neurophysiology. 77: 1075-86. PMID 9084583  1
1996 Urban NN, Henze DA, Lewis DA, Barrionuevo G. Properties of LTP induction in the CA3 region of the primate hippocampus. Learning & Memory (Cold Spring Harbor, N.Y.). 3: 86-95. PMID 10456079  1
1996 Henze DA, Cameron WE, Barrionuevo G. Dendritic morphology and its effects on the amplitude and rise-time of synaptic signals in hippocampal CA3 pyramidal cells. The Journal of Comparative Neurology. 369: 331-44. PMID 8743416 DOI: 10.1002/(SICI)1096-9861(19960603)369:3<331::AID-CNE1>3.0.CO;2-6  1
1993 Fleck MW, Henze DA, Barrionuevo G, Palmer AM. Aspartate and glutamate mediate excitatory synaptic transmission in area CA1 of the hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 3944-55. PMID 7690067  1
Show low-probability matches.