| Year |
Citation |
Score |
| 2024 |
Aldous SG, Smith EJ, Landles C, Osborne GF, Cañibano-Pico M, Nita IM, Phillips J, Zhang Y, Jin B, Hirst MB, Benn CL, Bond BC, Edelmann W, Greene JR, Bates GP. A CAG repeat threshold for therapeutics targeting somatic instability in Huntington's disease. Brain : a Journal of Neurology. PMID 38387080 DOI: 10.1093/brain/awae063 |
0.372 |
|
| 2020 |
Benn CL, Dawson LA. Clinically Precedented Protein Kinases: Rationale for Their Use in Neurodegenerative Disease. Frontiers in Aging Neuroscience. 12: 242. PMID 33117143 DOI: 10.3389/fnagi.2020.00242 |
0.305 |
|
| 2020 |
Landles C, Milton RE, Ali N, Flomen R, Flower M, Schindler F, Gomez-Paredes C, Bondulich MK, Osborne GF, Goodwin D, Salsbury G, Benn CL, Sathasivam K, Smith EJ, Tabrizi SJ, et al. Subcellular Localization And Formation Of Huntingtin Aggregates Correlates With Symptom Onset And Progression In A Huntington'S Disease Model. Brain Communications. 2: fcaa066. PMID 32954323 DOI: 10.1093/braincomms/fcaa066 |
0.606 |
|
| 2020 |
Benn CL, Gibson KR, Reynolds DS. Drugging DNA Damage Repair Pathways for Trinucleotide Repeat Expansion Diseases. Journal of Huntington's Disease. PMID 32925081 DOI: 10.3233/JHD-200421 |
0.396 |
|
| 2017 |
Schwartzentruber J, Foskolou S, Kilpinen H, Rodrigues J, Alasoo K, Knights AJ, Patel M, Goncalves A, Ferreira R, Benn CL, Wilbrey A, Bictash M, Impey E, Cao L, Lainez S, et al. Molecular and functional variation in iPSC-derived sensory neurons. Nature Genetics. PMID 29229984 DOI: 10.1038/S41588-017-0005-8 |
0.333 |
|
| 2017 |
Bryant DT, Landles C, Papadopoulou AS, Benjamin AC, Duckworth JK, Rosahl T, Benn CL, Bates GP. Disruption to schizophrenia-associated gene Fez1 in the hippocampus of HDAC11 knockout mice. Scientific Reports. 7: 11900. PMID 28928414 DOI: 10.1038/s41598-017-11630-1 |
0.613 |
|
| 2015 |
Choudhary P, Dodsworth BT, Sidders B, Gutteridge A, Michaelides C, Duckworth JK, Whiting PJ, Benn CL. A FOXM1 Dependent Mesenchymal-Epithelial Transition in Retinal Pigment Epithelium Cells. Plos One. 10: e0130379. PMID 26121260 DOI: 10.1371/Journal.Pone.0130379 |
0.327 |
|
| 2015 |
Choudhary P, Dodsworth BT, Sidders B, Gutteridge A, Michaelides C, Duckworth JK, Whiting PJ, Benn CL. FOXM1 binds to promoters of proliferation associated genes. Plos One. DOI: 10.1371/Journal.Pone.0130379.G004 |
0.424 |
|
| 2014 |
Barsyte-Lovejoy D, Li F, Oudhoff MJ, Tatlock JH, Dong A, Zeng H, Wu H, Freeman SA, Schapira M, Senisterra GA, Kuznetsova E, Marcellus R, Allali-Hassani A, Kennedy S, Lambert JP, ... ... Benn CL, et al. (R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 12853-8. PMID 25136132 DOI: 10.1073/Pnas.1407358111 |
0.395 |
|
| 2011 |
Mielcarek M, Benn CL, Franklin SA, Smith DL, Woodman B, Marks PA, Bates GP. SAHA decreases HDAC 2 and 4 levels in vivo and improves molecular phenotypes in the R6/2 mouse model of Huntington's disease. Plos One. 6: e27746. PMID 22140466 DOI: 10.1371/journal.pone.0027746 |
0.66 |
|
| 2010 |
Benn CL, Luthi-Carter R, Kuhn A, Sadri-Vakili G, Blankson KL, Dalai SC, Goldstein DR, Spires TL, Pritchard J, Olson JM, van Dellen A, Hannan AJ, Cha JH. Environmental enrichment reduces neuronal intranuclear inclusion load but has no effect on messenger RNA expression in a mouse model of Huntington disease. Journal of Neuropathology and Experimental Neurology. 69: 817-27. PMID 20613636 DOI: 10.1097/Nen.0B013E3181Ea167F |
0.71 |
|
| 2009 |
Bett JS, Benn CL, Ryu KY, Kopito RR, Bates GP. The polyubiquitin Ubc gene modulates histone H2A monoubiquitylation in the R6/2 mouse model of Huntington's disease. Journal of Cellular and Molecular Medicine. 13: 2645-57. PMID 19602042 DOI: 10.1111/j.1582-4934.2008.00543.x |
0.66 |
|
| 2009 |
Benn CL, Butler R, Mariner L, Nixon J, Moffitt H, Mielcarek M, Woodman B, Bates GP. Genetic knock-down of HDAC7 does not ameliorate disease pathogenesis in the R6/2 mouse model of Huntington's disease. Plos One. 4: e5747. PMID 19484127 DOI: 10.1371/journal.pone.0005747 |
0.673 |
|
| 2008 |
Benn CL, Fox H, Bates GP. Optimisation of region-specific reference gene selection and relative gene expression analysis methods for pre-clinical trials of Huntington's disease. Molecular Neurodegeneration. 3: 17. PMID 18954449 DOI: 10.1186/1750-1326-3-17 |
0.625 |
|
| 2008 |
Benn CL, Sun T, Sadri-Vakili G, McFarland KN, DiRocco DP, Yohrling GJ, Clark TW, Bouzou B, Cha JH. Huntingtin modulates transcription, occupies gene promoters in vivo, and binds directly to DNA in a polyglutamine-dependent manner. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10720-33. PMID 18923047 DOI: 10.1523/JNEUROSCI.2126-08.2008 |
0.702 |
|
| 2008 |
Björkqvist M, Wild EJ, Thiele J, Silvestroni A, Andre R, Lahiri N, Raibon E, Lee RV, Benn CL, Soulet D, Magnusson A, Woodman B, Landles C, Pouladi MA, Hayden MR, et al. A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease. The Journal of Experimental Medicine. 205: 1869-77. PMID 18625748 DOI: 10.1084/Jem.20080178 |
0.55 |
|
| 2008 |
Wild EJ, Björkqvist M, Thiele J, Silvestroni A, Soulet D, Magnusson A, Benn CL, Woodman B, André R, Landles C, Pouladi MA, Hayden MR, Khalili-Shirazi A, Lowdell MW, Brundin P, et al. P3-377: A novel pathogenic pathway of immune activation detectable before cinical onset in Huntington's disease Alzheimer's & Dementia. 4: T632-T632. DOI: 10.1016/J.Jalz.2008.05.1947 |
0.512 |
|
| 2007 |
Benn CL, Slow EJ, Farrell LA, Graham R, Deng Y, Hayden MR, Cha JH. Glutamate receptor abnormalities in the YAC128 transgenic mouse model of Huntington's disease. Neuroscience. 147: 354-72. PMID 17544587 DOI: 10.1016/J.Neuroscience.2007.03.010 |
0.356 |
|
| 2007 |
Sadri-Vakili G, Bouzou B, Benn CL, Kim MO, Chawla P, Overland RP, Glajch KE, Xia E, Qiu Z, Hersch SM, Clark TW, Yohrling GJ, Cha JH. Histones associated with downregulated genes are hypo-acetylated in Huntington's disease models. Human Molecular Genetics. 16: 1293-306. PMID 17409194 DOI: 10.1093/Hmg/Ddm078 |
0.703 |
|
| 2006 |
Qiu Z, Norflus F, Singh B, Swindell MK, Buzescu R, Bejarano M, Chopra R, Zucker B, Benn CL, DiRocco DP, Cha JH, Ferrante RJ, Hersch SM. Sp1 is up-regulated in cellular and transgenic models of Huntington disease, and its reduction is neuroprotective. The Journal of Biological Chemistry. 281: 16672-80. PMID 16595660 DOI: 10.1074/Jbc.M511648200 |
0.451 |
|
| 2006 |
Chen-Plotkin AS, Sadri-Vakili G, Yohrling GJ, Braveman MW, Benn CL, Glajch KE, DiRocco DP, Farrell LA, Krainc D, Gines S, MacDonald ME, Cha JH. Decreased association of the transcription factor Sp1 with genes downregulated in Huntington's disease. Neurobiology of Disease. 22: 233-41. PMID 16442295 DOI: 10.1016/J.Nbd.2005.11.001 |
0.7 |
|
| 2005 |
Benn CL, Landles C, Li H, Strand AD, Woodman B, Sathasivam K, Li SH, Ghazi-Noori S, Hockly E, Faruque SM, Cha JH, Sharpe PT, Olson JM, Li XJ, Bates GP. Contribution of nuclear and extranuclear polyQ to neurological phenotypes in mouse models of Huntington's disease. Human Molecular Genetics. 14: 3065-78. PMID 16183657 DOI: 10.1093/Hmg/Ddi340 |
0.599 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2004 |
Benn CL, Farrell LA, Cha JH. Neurotransmitter receptor analysis in transgenic mouse models. Methods in Molecular Biology (Clifton, N.J.). 277: 231-60. PMID 15201460 DOI: 10.1385/1-59259-804-8:231 |
0.295 |
|
| 2016 |
Choudhary P, Gutteridge A, Impey E, Storer RI, Owen RM, Whiting PJ, Bictash M, Benn CL. Targeting the cAMP and Transforming Growth Factor-β Pathway Increases Proliferation to Promote Re-Epithelialization of Human Stem Cell-Derived Retinal Pigment Epithelium. Stem Cells Translational Medicine. PMID 27112176 DOI: 10.5966/Sctm.2015-0247 |
0.275 |
|
| 2017 |
Choudhary P, Armstrong EJ, Jorgensen CC, Piotrowski M, Barthmes M, Torella R, Johnston SE, Maruyama Y, Janiszewski JS, Storer RI, Skerratt SE, Benn CL. Discovery of Compounds that Positively Modulate the High Affinity Choline Transporter. Frontiers in Molecular Neuroscience. 10: 40. PMID 28289374 DOI: 10.3389/fnmol.2017.00040 |
0.27 |
|
| 2019 |
Mauricio R, Benn C, Davis J, Dawson G, Dawson LA, Evans A, Fox N, Gallacher J, Hutton M, Isaac J, Jones DNC, Jones L, Lalli G, Libri V, Lovestone S, et al. Tackling gaps in developing life-changing treatments for dementia. Alzheimer's & Dementia (New York, N. Y.). 5: 241-253. PMID 31297438 DOI: 10.1016/J.Trci.2019.05.001 |
0.27 |
|
| 2018 |
Benn CL, Dua P, Gurrell R, Loudon P, Pike A, Storer RI, Vangjeli C. Physiology of Hyperuricemia and Urate-Lowering Treatments. Frontiers in Medicine. 5: 160. PMID 29904633 DOI: 10.3389/fmed.2018.00160 |
0.268 |
|
| 2006 |
Xiao D, Bastia E, Xu YH, Benn CL, Cha JH, Peterson TS, Chen JF, Schwarzschild MA. Forebrain adenosine A2A receptors contribute to L-3,4-dihydroxyphenylalanine-induced dyskinesia in hemiparkinsonian mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 13548-55. PMID 17192438 DOI: 10.1523/Jneurosci.3554-06.2006 |
0.265 |
|
| 2014 |
Young GT, Gutteridge A, Fox HD, Wilbrey AL, Cao L, Cho LT, Brown AR, Benn CL, Kammonen LR, Friedman JH, Bictash M, Whiting P, Bilsland JG, Stevens EB. Characterizing human stem cell-derived sensory neurons at the single-cell level reveals their ion channel expression and utility in pain research. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1530-43. PMID 24832007 DOI: 10.1038/Mt.2014.86 |
0.246 |
|
| 2016 |
Storer RI, Owen RM, Pike A, Benn CL, Armstrong E, Blakemore DC, Bictash M, Costelloe K, Impey E, Milliken PH, Mortimer-Cassen E, Pearce HJ, Pibworth B, Toschi G. The discovery and evaluation of diaryl ether heterocyclic sulfonamides as URAT1 inhibitors for the treatment of gout Medchemcomm. 7: 1587-1595. DOI: 10.1039/C6Md00190D |
0.232 |
|
| 2016 |
Pike A, Storer RI, Owen RM, Armstrong E, Benn CL, Bictash M, Cheung KFK, Costelloe K, Dardennes E, Impey E, Milliken PH, Mortimer-Cassen E, Pearce HJ. The design, synthesis and evaluation of low molecular weight acidic sulfonamides as URAT1 inhibitors for the treatment of gout Medchemcomm. 7: 1572-1579. DOI: 10.1039/C6Md00191B |
0.218 |
|
| 2019 |
Schwartzentruber J, Foskolou S, Kilpinen H, Rodrigues J, Alasoo K, Knights AJ, Patel M, Goncalves A, Ferreira R, Benn CL, Wilbrey A, Bictash M, Impey E, Cao L, Lainez S, et al. Publisher Correction: Molecular and functional variation in iPSC-derived sensory neurons. Nature Genetics. PMID 31160811 DOI: 10.1038/S41588-019-0445-4 |
0.216 |
|
| 2015 |
Nahorski MS, Al-Gazali L, Hertecant J, Owen DJ, Borner GH, Chen YC, Benn CL, Carvalho OP, Shaikh SS, Phelan A, Robinson MS, Royle SJ, Geoffrey Woods C. A novel disorder reveals clathrin heavy chain-22 is essential for human pain and touch development. Brain : a Journal of Neurology. PMID 26068709 DOI: 10.1093/brain/awv149 |
0.183 |
|
| 2022 |
Kandel P, Semerci F, Mishra R, Choi W, Bajic A, Baluya D, Ma L, Chen K, Cao AC, Phongmekhin T, Matinyan N, Jiménez-Panizo A, Chamakuri S, Raji IO, Chang L, ... ... Benn CL, et al. Oleic acid is an endogenous ligand of TLX/NR2E1 that triggers hippocampal neurogenesis. Proceedings of the National Academy of Sciences of the United States of America. 119: e2023784119. PMID 35333654 DOI: 10.1073/pnas.2023784119 |
0.136 |
|
| 2014 |
Young GT, Gutteridge A, Fox H, Wilbrey AL, Cao L, Cho LT, Brown AR, Benn CL, Kammonen LR, Friedman JH, Bictash M, Whiting P, Bilsland JG, Stevens EB. Characterizing Human Stem Cell-derived Sensory Neurons at the Single-cell Level Reveals Their Ion Channel Expression and Utility in Pain Research. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1530-1543. PMID 28147249 DOI: 10.1038/mt.2014.86 |
0.104 |
|
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