| Year |
Citation |
Score |
| 2023 |
Muhammad YA, Omar AM, Ahmed F, Khayat MT, Malebari AM, Ibrahim SM, Mass SA, Elfaky MA, El-Araby ME. Exploring antiproliferative activities and kinase profile of ortho-substituted N-(4-(2-(benzylamino)-2-oxoethyl)phenyl)benzamides. Chemical Biology & Drug Design. PMID 37873688 DOI: 10.1111/cbdd.14379 |
0.436 |
|
| 2023 |
Omar AM, Abdulmalik O, El-Say KM, Ghatge MS, Cyril-Olutayo M, Paredes S, Al-Awadh M, El-Araby ME, Safo MK. Targeted modification of furan-2-carboxaldehydes into Michael acceptor analogs yielded long-acting hemoglobin modulators with dual antisickling activities. Chemical Biology & Drug Design. PMID 37798397 DOI: 10.1111/cbdd.14371 |
0.433 |
|
| 2022 |
Khayat MT, Omar AM, Ahmed F, Khan MI, Ibrahim SM, Muhammad YA, Malebari AM, Neamatallah T, El-Araby ME. Insights on Cancer Cell Inhibition, Subcellular Activities, and Kinase Profile of Phenylacetamides Pending 1-Imidazol-5-One Variants. Frontiers in Pharmacology. 12: 794325. PMID 35069208 DOI: 10.3389/fphar.2021.794325 |
0.45 |
|
| 2020 |
Omar AM, Abdulmalik O, Ghatge MS, Muhammad YA, Paredes SD, El-Araby ME, Safo MK. An Investigation of Structure-Activity Relationships of Azolylacryloyl Derivatives Yielded Potent and Long-Acting Hemoglobin Modulators for Reversing Erythrocyte Sickling. Biomolecules. 10. PMID 33147875 DOI: 10.3390/biom10111508 |
0.422 |
|
| 2020 |
Omar AM, Bajorath J, Ihmaid S, Mohamed HM, El-Agrody AM, Mora A, El-Araby ME, Ahmed HEA. Novel molecular discovery of promising amidine-based thiazole analogues as potent dual Matrix Metalloproteinase-2 and 9 inhibitors: Anticancer activity data with prominent cell cycle arrest and DNA fragmentation analysis effects. Bioorganic Chemistry. 101: 103992. PMID 32554279 DOI: 10.1016/J.Bioorg.2020.103992 |
0.432 |
|
| 2020 |
Elfaky MA, El-Halawany AM, Koshak AE, Alshali KZ, El-Araby ME, Khayat MT, Abdallah HM. Bioassay Guided Isolation and Docking Studies of a Potential β-Lactamase Inhibitor from . Molecules (Basel, Switzerland). 25. PMID 32486455 DOI: 10.3390/Molecules25112566 |
0.481 |
|
| 2020 |
Omar AM, El-Araby ME, Abdelghany TM, Safo MK, Ahmed MH, Boothello R, Patel BB, Abdel-Bakky MS, Malebari AM, Ahmed HEA, Elhaggar RS. Introducing of potent cytotoxic novel 2-(aroylamino)cinnamamide derivatives against colon cancer mediated by dual apoptotic signal activation and oxidative stress. Bioorganic Chemistry. 101: 103953. PMID 32474179 DOI: 10.1016/J.Bioorg.2020.103953 |
0.5 |
|
| 2020 |
Omar AM, Elfaky MA, Arold ST, Soror SH, Khayat MT, Asfour HZ, Bamane FH, El-Araby ME. 1-Imidazole-2,5-Dicarboxamides as NS4A Peptidomimetics: Identification of a New Approach to Inhibit HCV-NS3 Protease. Biomolecules. 10. PMID 32245218 DOI: 10.3390/biom10030479 |
0.347 |
|
| 2019 |
Omar AM, David T, Pagare PP, Ghatge MS, Chen Q, Mehta A, Zhang Y, Abdulmalik O, Naghi AH, El-Araby ME, Safo MK. Structural modification of azolylacryloyl derivatives yields a novel class of covalent modifiers of hemoglobin as potential antisickling agents. Medchemcomm. 10: 1900-1906. PMID 32206236 DOI: 10.1039/C9Md00291J |
0.432 |
|
| 2018 |
Omar AM, Abdelghany TM, Abdel-Bakky MS, Alahdal AM, Radwan MF, El-Araby ME. Design, Synthesis and Antiproliferative Activities of Oxidative Stress Inducers Based on 2-styryl-3,5-dihydro-4H-imidazol-4-one Scaffold. Chemical & Pharmaceutical Bulletin. PMID 30047515 DOI: 10.1248/Cpb.C18-00398 |
0.484 |
|
| 2018 |
Mohamed MS, Mansour YE, Amin HK, El-Araby ME. Molecular modelling insights into a physiologically favourable approach to eicosanoid biosynthesis inhibition through novel thieno[2,3-b]pyridine derivatives. Journal of Enzyme Inhibition and Medicinal Chemistry. 33: 755-767. PMID 29651867 DOI: 10.1080/14756366.2018.1457657 |
0.466 |
|
| 2017 |
Alasmary FAS, Alnahdi FS, Ben Bacha A, El-Araby AM, Moubayed N, Alafeefy AM, El-Araby ME. New quinoxalinone inhibitors targeting secreted phospholipase A2 and α-glucosidase. Journal of Enzyme Inhibition and Medicinal Chemistry. 32: 1143-1151. PMID 28856929 DOI: 10.1080/14756366.2017.1363743 |
0.465 |
|
| 2017 |
El-Araby ME, Omar AM, Khayat MT, Assiri HA, Al-Abd AM. Molecular Mimics of Classic P-Glycoprotein Inhibitors as Multidrug Resistance Suppressors and Their Synergistic Effect on Paclitaxel. Plos One. 12: e0168938. PMID 28068430 DOI: 10.1371/Journal.Pone.0168938 |
0.406 |
|
| 2016 |
Omar AM, Mahran MA, Ghatge MS, Bamane FH, Ahmed MH, El-Araby ME, Abdulmalik O, Safo MK. Aryloxyalkanoic Acids as Non-Covalent Modifiers of the Allosteric Properties of Hemoglobin. Molecules (Basel, Switzerland). 21. PMID 27529207 DOI: 10.3390/Molecules21081057 |
0.473 |
|
| 2015 |
Omar AM, Mahran MA, Ghatge MS, Chowdhury N, Bamane FHA, El-Araby ME, Abdulmalik O, Safo MK. Identification of a novel class of covalent modifiers of hemoglobin as potential antisickling agents Organic and Biomolecular Chemistry. 13: 6353-6370. PMID 25974708 DOI: 10.1039/C5Ob00367A |
0.47 |
|
| 2013 |
Elsayed MS, El-Araby ME, Serya RA, El-Khatib AH, Linscheid MW, Abouzid KA. Structure-based design and synthesis of novel pseudosaccharine derivatives as antiproliferative agents and kinase inhibitors. European Journal of Medicinal Chemistry. 61: 122-31. PMID 23063746 DOI: 10.1016/J.Ejmech.2012.09.039 |
0.482 |
|
| 2012 |
El-Araby M, Omar A, Hassanein HH, El-Helby AG, Abdel-Rahman AA. Design, synthesis and in vivo anti-inflammatory activities of 2,4-diaryl-5-4H-imidazolone derivatives. Molecules (Basel, Switzerland). 17: 12262-75. PMID 23079497 DOI: 10.3390/Molecules171012262 |
0.41 |
|
| 2012 |
Elsayed MS, El-Araby ME, Serya RT, Abouzid KA. Virtual screening and synthesis of new chemical scaffolds as VEGFR-2 kinase inhibitors. Arzneimittel-Forschung. 62: 554-60. PMID 23023518 DOI: 10.1055/S-0032-1323759 |
0.437 |
|
| 2012 |
El Ella DAAE, Saleh KA, Hassan M, Hamdy N, El-Araby ME, Abouzid KAM. Synthesis and anti-proliferative activity of substituted- anilinoquinazolines and its relation to EGFR inhibition Arzneimittel-Forschung/Drug Research. 62: 360-366. PMID 22723174 DOI: 10.1055/S-0032-1312601 |
0.527 |
|
| 2010 |
Abouzid KAM, Khalil NA, Ahmed EM, El-Latif HAA, El-Araby ME. Structure-based molecular design, synthesis, and in vivo anti-inflammatory activity of pyridazinone derivatives as nonclassic COX-2 inhibitors Medicinal Chemistry Research. 19: 629-642. DOI: 10.1007/S00044-009-9218-4 |
0.421 |
|
| 2004 |
El-Araby M, Pottorf RS, Player MR. Synthesis of a 2, 4, 8-trisubstituted pyrimidino[5, 4-d]pyrimidine library via sequential SNAr reactions on solid-phase. Combinatorial Chemistry & High Throughput Screening. 7: 413-421. PMID 15320708 DOI: 10.2174/1386207043328571 |
0.322 |
|
| 2004 |
El-Araby ME, Bernacki RJ, Makara GM, Pera PJ, Anderson WK. Synthesis, molecular modeling, and evaluation of nonphenolic indole analogs of mycophenolic acid. Bioorganic & Medicinal Chemistry. 12: 2867-79. PMID 15142547 DOI: 10.1016/J.Bmc.2004.03.048 |
0.462 |
|
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