| Year |
Citation |
Score |
| 2020 |
Burnett M, Abuetabh Y, Wronski A, Shen F, Persad S, Leng R, Eisenstat D, Sergi C. Graphene Oxide Nanoparticles Induce Apoptosis in wild-type and CRISPR/Cas9-IGF/IGFBP3 knocked-out Osteosarcoma Cells. Journal of Cancer. 11: 5007-5023. PMID 32742448 DOI: 10.7150/Jca.46464 |
0.342 |
|
| 2019 |
Japoni S, Song X, Leng R, Eisenstat D. BIOL-04. DISTAL-LESS/DLX2 HOMEOBOX GENE REGULATION OF CHEMOKINE RECEPTOR CXCR4 - ROLE IN MIGRATION IN FOREBRAIN DEVELOPMENT AND CNS TUMORS Neuro-Oncology. 21: ii66-ii67. DOI: 10.1093/Neuonc/Noz036.017 |
0.352 |
|
| 2018 |
Chai C, Wu H, Wang B, Eisenstat DD, Leng RP. MicroRNA-498 promotes proliferation and migration by targeting the tumor suppressor PTEN in breast cancer cells. Carcinogenesis. PMID 29985991 DOI: 10.1093/Carcin/Bgy092 |
0.377 |
|
| 2017 |
Wang B, Wu H, Chai C, Lewis J, Pichiorri F, Eisenstat DD, Pomeroy S, Leng RP. MicroRNA-1301 Suppresses Tumor Cell Migration and Invasion by Targeting the p53/UBE4B Pathway in Multiple Human Cancer Cells. Cancer Letters. PMID 28483517 DOI: 10.1016/J.Canlet.2017.04.038 |
0.57 |
|
| 2016 |
Armstrong SR, Wu H, Wang B, Abuetabh Y, Sergi C, Leng RP. The Regulation of Tumor Suppressor p63 by the Ubiquitin-Proteasome System. International Journal of Molecular Sciences. 17. PMID 27929429 DOI: 10.3390/Ijms17122041 |
0.582 |
|
| 2016 |
Armstrong SR, Wang B, Abuetabh Y, Leng R. Abstract LB-022: The E3-ligase CHIP negatively regulates the expression and function of the tumor suppressor TAp63 through ubiquitination and subsequent proteasome-mediated degradation Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-022 |
0.568 |
|
| 2015 |
Du C, Wu H, Leng RP. UBE4B targets phosphorylated p53 at serines 15 and 392 for degradation. Oncotarget. PMID 26673821 DOI: 10.18632/Oncotarget.6555 |
0.515 |
|
| 2015 |
Wu H, Leng RP. MDM2 mediates p73 ubiquitination: a new molecular mechanism for suppression of p73 function. Oncotarget. 6: 21479-92. PMID 26025930 DOI: 10.18632/Oncotarget.4086 |
0.567 |
|
| 2015 |
Al-Bahrani R, Nagamori S, Leng R, Petryk A, Sergi C. Differential Expression of Sonic Hedgehog Protein in Human Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma Pathology and Oncology Research. 21: 901-908. DOI: 10.1007/S12253-015-9918-7 |
0.304 |
|
| 2015 |
Wu H, Leng RP. MDM2 mediates p73 ubiquitination: A new molecular mechanism for suppression of p73 function Oncotarget. 6: 21479-21492. |
0.426 |
|
| 2013 |
Abou Zeinab R, Wu H, Sergi C, Leng RP. Residues 240-250 in the C-terminus of the Pirh2 protein complement the function of the RING domain in self-ubiquitination of the Pirh2 protein Plos One. 8. PMID 24367557 DOI: 10.1371/Journal.Pone.0082803 |
0.401 |
|
| 2013 |
Bagashev A, Fan S, Mukerjee R, Claudio PP, Chabrashvili T, Leng RP, Benchimol S, Sawaya BE. Cdk9 phosphorylates Pirh2 protein and prevents degradation of p53 protein. Cell Cycle (Georgetown, Tex.). 12: 1569-77. PMID 23603988 DOI: 10.4161/Cc.24733 |
0.446 |
|
| 2013 |
Abou Zeinab RM, Leng R. The role of Pirh2 C-terminal residues and ubiquitin lysine chains in ubiquitination mechanism. Journal of Clinical Oncology. 31: 11110-11110. DOI: 10.1200/Jco.2013.31.15_Suppl.11110 |
0.464 |
|
| 2012 |
Zeinab RA, Wu H, Sergi C, Leng R. UBE4B: A promising regulatory molecule in neuronal death and survival International Journal of Molecular Sciences. 13: 16865-16879. PMID 23222733 DOI: 10.3390/Ijms131216865 |
0.377 |
|
| 2011 |
Wu H, Zeinab RA, Flores ER, Leng RP. Pirh2, a ubiquitin E3 ligase, inhibits p73 transcriptional activity by promoting its ubiquitination Molecular Cancer Research. 9: 1780-1790. PMID 21994467 DOI: 10.1158/1541-7786.Mcr-11-0157 |
0.56 |
|
| 2011 |
Wu H, Leng RP. UBE4B, a ubiquitin chain assembly factor, is required for MDM2-mediated p53 polyubiquitination and degradation Cell Cycle. 10: 1912-1915. PMID 21558803 DOI: 10.4161/Cc.10.12.15882 |
0.559 |
|
| 2011 |
Wu H, Pomeroy SL, Ferreira M, Teider N, Mariani J, Nakayama KI, Hatakeyama S, Tron VA, Saltibus LF, Spyracopoulos L, Leng RP. UBE4B promotes Hdm2-mediated degradation of the tumor suppressor p53. Nature Medicine. 17: 347-55. PMID 21317885 DOI: 10.1038/Nm.2283 |
0.592 |
|
| 2006 |
Lin Y, Leng RP, Benchimol S. Identification of p53-regulated genes by the method of differential display. Methods in Molecular Biology (Clifton, N.J.). 317: 193-206. PMID 16264230 DOI: 10.1385/1-59259-968-0:193 |
0.451 |
|
| 2003 |
Leng RP, Lin Y, Ma W, Wu H, Lemmers B, Chung S, Parant JM, Lozano G, Hakem R, Benchimol S. Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation. Cell. 112: 779-91. PMID 12654245 DOI: 10.1016/S0092-8674(03)00193-4 |
0.525 |
|
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