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Michael J. Owen, PhD - Publications

Affiliations: 
Psychological Medicine, Neuropsychiatric Genetics and Genomics Cardiff University, Cardiff, Wales, United Kingdom 
Website:
http://conference.iepa.org.au/speakers/professor-michael-j-owen/

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Year Citation  Score
2020 Legge SE, Christensen RH, Petersen L, Pardiñas AF, Bracher-Smith M, Knapper S, Bybjerg-Grauholm J, Baekvad-Hansen M, Hougaard DM, Werge T, Nordentoft M, Mortensen PB, Owen MJ, O'Donovan MC, Benros ME, et al. The Duffy-null genotype and risk of infection. Human Molecular Genetics. PMID 32959868 DOI: 10.1093/Hmg/Ddaa208  0.307
2020 Dima DC, Adams R, Linden SC, Baird A, Smith J, Foley S, Perry G, Routley BC, Magazzini L, Drakesmith M, Williams N, Doherty J, van den Bree MBM, Owen MJ, Hall J, et al. Electrophysiological network alterations in adults with copy number variants associated with high neurodevelopmental risk. Translational Psychiatry. 10: 324. PMID 32958742 DOI: 10.1038/S41398-020-00998-W  0.364
2020 Cunningham AC, Hall J, Einfeld S, Owen MJ, van den Bree MBM. Assessment of emotions and behaviour by the Developmental Behaviour Checklist in young people with neurodevelopmental CNVs. Psychological Medicine. 1-13. PMID 32643597 DOI: 10.1017/S0033291720002330  0.305
2020 Jones HJ, Martin D, Lewis SJ, Davey Smith G, O'Donovan MC, Owen MJ, Walters JTR, Zammit S. A Mendelian randomization study of the causal association between anxiety phenotypes and schizophrenia. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 32578352 DOI: 10.1002/Ajmg.B.32808  0.378
2020 Jones HJ, Hammerton G, McCloud T, Hines LA, Wright C, Gage SH, Holmans P, Jones PB, Davey Smith G, Linden DEJ, O'Donovan MC, Owen MJ, Walters JT, Munafò MR, Heron J, et al. Examining pathways between genetic liability for schizophrenia and patterns of tobacco and cannabis use in adolescence. Psychological Medicine. 1-8. PMID 32515721 DOI: 10.1017/S0033291720001798  0.344
2020 Byrne EM, Zhu Z, Qi T, Skene NG, Bryois J, Pardinas AF, Stahl E, Smoller JW, Rietschel M, Owen MJ, Walters JTR, O'Donovan MC, McGrath JG, et al. Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders. Molecular Psychiatry. PMID 32398722 DOI: 10.1038/S41380-020-0705-9  0.382
2020 Martin J, Hosking G, Wadon M, Agha SS, Langley K, Rees E, Owen MJ, O'Donovan M, Kirov G, Thapar A. A brief report: de novo copy number variants in children with attention deficit hyperactivity disorder. Translational Psychiatry. 10: 135. PMID 32398668 DOI: 10.1038/S41398-020-0821-Y  0.38
2020 Montagnese M, Knolle F, Haarsma J, Griffin JD, Richards A, Vertes PE, Kiddle B, Fletcher PC, Jones PB, Owen MJ, Fonagy P, Bullmore ET, Dolan RJ, Moutoussis M, et al. Reinforcement learning as an intermediate phenotype in psychosis? Deficits sensitive to illness stage but not associated with polygenic risk of schizophrenia in the general population. Schizophrenia Research. PMID 32389614 DOI: 10.1016/J.Schres.2020.04.022  0.362
2020 Hall LS, Pain O, O'Brien HE, Anney R, Walters JTR, Owen MJ, O'Donovan MC, Bray NJ. Cis-effects on gene expression in the human prenatal brain associated with genetic risk for neuropsychiatric disorders. Molecular Psychiatry. PMID 32366953 DOI: 10.1038/S41380-020-0743-3  0.405
2020 Rees E, Owen MJ. Translating insights from neuropsychiatric genetics and genomics for precision psychiatry. Genome Medicine. 12: 43. PMID 32349784 DOI: 10.1186/S13073-020-00734-5  0.331
2020 Sullivan PF, Owen MJ. Increasing the Clinical Psychiatric Knowledge Base About Pathogenic Copy Number Variation. The American Journal of Psychiatry. 177: 204-209. PMID 32114777 DOI: 10.1176/Appi.Ajp.2019.19040335  0.348
2020 Niarchou M, Byrne EM, Trzaskowski M, Sidorenko J, Kemper KE, McGrath JJ, O' Donovan MC, Owen MJ, Wray NR. Genome-wide association study of dietary intake in the UK biobank study and its associations with schizophrenia and other traits. Translational Psychiatry. 10: 51. PMID 32066663 DOI: 10.1038/S41398-020-0688-Y  0.355
2020 Ching CRK, Gutman BA, Sun D, Villalon Reina J, Ragothaman A, Isaev D, Zavaliangos-Petropulu A, Lin A, Jonas RK, Kushan L, Pacheco-Hansen L, Vajdi A, Forsyth JK, Jalbrzikowski M, Bakker G, ... ... Owen MJ, et al. Mapping Subcortical Brain Alterations in 22q11.2 Deletion Syndrome: Effects of Deletion Size and Convergence With Idiopathic Neuropsychiatric Illness. The American Journal of Psychiatry. appiajp201919060583. PMID 32046535 DOI: 10.1176/Appi.Ajp.2019.19060583  0.34
2020 Cleynen I, Engchuan W, Hestand MS, Heung T, Holleman AM, Johnston HR, Monfeuga T, McDonald-McGinn DM, Gur RE, Morrow BE, Swillen A, Vorstman JAS, Bearden CE, Chow EWC, van den Bree M, ... ... Owen MJ, et al. Genetic contributors to risk of schizophrenia in the presence of a 22q11.2 deletion. Molecular Psychiatry. PMID 32015465 DOI: 10.1038/S41380-020-0654-3  0.388
2020 Foley C, Heron EA, Harold D, Walters J, Owen M, O'Donovan M, Sebat J, Kelleher E, Mooney C, Durand A, Pinto C, Cormican P, Morris D, Donohoe G, Gill M, et al. Identifying schizophrenia patients who carry pathogenic genetic copy number variants using standard clinical assessment: retrospective cohort study. The British Journal of Psychiatry : the Journal of Mental Science. 1-5. PMID 31964429 DOI: 10.1192/Bjp.2019.262  0.41
2020 Rees E, Han J, Morgan J, Carrera N, Escott-Price V, Pocklington AJ, Duffield M, Hall LS, Legge SE, Pardiñas AF, Richards AL, Roth J, Lezheiko T, Kondratyev N, Kaleda V, ... ... Owen MJ, et al. De novo mutations identified by exome sequencing implicate rare missense variants in SLC6A1 in schizophrenia. Nature Neuroscience. PMID 31932766 DOI: 10.1038/S41593-019-0565-2  0.429
2020 Bray NJ, Owen MJ. A Developmental Perspective on the Convergence of Genetic Risk Factors for Neuropsychiatric Disorders. Biological Psychiatry. 87: 98-99. PMID 31856960 DOI: 10.1016/J.Biopsych.2019.09.010  0.317
2020 Dennison C, Legge S, Hubbard L, Lynham A, Holmans P, Cardno A, Owen MJ, O’Donovan M, Walters J. S178. Should Schizoaffective Disorder Depressed-Type Be Distinct From Schizophrenia? Analysis Of Genetic Liability And Lifetime Clinical Characteristics Schizophrenia Bulletin. 46. DOI: 10.1093/Schbul/Sbaa031.244  0.302
2019 Zhao Y, Diacou A, Johnston HR, Musfee FI, McDonald-McGinn DM, McGinn D, Crowley TB, Repetto GM, Swillen A, Breckpot J, Vermeesch JR, Kates WR, Digilio MC, Unolt M, Marino B, ... ... Owen MJ, et al. Complete Sequence of the 22q11.2 Allele in 1,053 Subjects with 22q11.2 Deletion Syndrome Reveals Modifiers of Conotruncal Heart Defects. American Journal of Human Genetics. PMID 31870554 DOI: 10.1016/J.Ajhg.2019.11.010  0.365
2019 Szatkiewicz JP, Fromer M, Nonneman RJ, Ancalade N, Johnson JS, Stahl EA, Rees E, Bergen SE, Hultman CM, Kirov G, O'Donovan M, Owen M, Holmans P, Sklar P, Sullivan PF, et al. Characterization of Single Gene Copy Number Variants in Schizophrenia. Biological Psychiatry. PMID 31767120 DOI: 10.1016/J.Biopsych.2019.09.023  0.356
2019 Lewis KJS, Richards A, Karlsson R, Leonenko G, Jones SE, Jones HJ, Gordon-Smith K, Forty L, Escott-Price V, Owen MJ, Weedon MN, Jones L, Craddock N, Jones I, Landén M, et al. Comparison of Genetic Liability for Sleep Traits Among Individuals With Bipolar Disorder I or II and Control Participants. Jama Psychiatry. PMID 31751445 DOI: 10.1001/Jamapsychiatry.2019.4079  0.306
2019 Hall LS, Medway CW, Pain O, Pardinas AF, Rees EG, Escott-Price V, Pocklington A, Bray NJ, Holmans PA, Walters JTR, Owen MJ, O'Donovan MC. A Transcriptome-Wide Association Study implicates specific pre- and post-synaptic abnormalities in Schizophrenia. Human Molecular Genetics. PMID 31691811 DOI: 10.1093/Hmg/Ddz253  0.394
2019 van der Meer D, Sønderby IE, Kaufmann T, Walters GB, Abdellaoui A, Ames D, Amunts K, Andersson M, Armstrong NJ, Bernard M, Blackburn NB, Blangero J, Boomsma DI, Brodaty H, ... ... Owen MJ, et al. Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition. Jama Psychiatry. 1-11. PMID 31665216 DOI: 10.1001/Jamapsychiatry.2019.3779  0.317
2019 Legge SE, Jones HJ, Kendall KM, Pardiñas AF, Menzies G, Bracher-Smith M, Escott-Price V, Rees E, Davis KAS, Hotopf M, Savage JE, Posthuma D, Holmans P, Kirov G, Owen MJ, et al. Association of Genetic Liability to Psychotic Experiences With Neuropsychotic Disorders and Traits. Jama Psychiatry. PMID 31553412 DOI: 10.1001/Jamapsychiatry.2019.2508  0.378
2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Owen MJ, et al. Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. PMID 31417202 DOI: 10.1038/s41588-019-0495-7  0.765
2019 Escott-Price V, Pardiñas AF, Santiago E, Walters J, Kirov G, Owen MJ, O'Donovan MC. The Relationship Between Common Variant Schizophrenia Liability and Number of Offspring in the UK Biobank: Response to Lawn et al. The American Journal of Psychiatry. 176: 574-575. PMID 31256626 DOI: 10.1176/Appi.Ajp.2019.19010071R  0.302
2019 Pain O, Pocklington AJ, Holmans PA, Bray NJ, O'Brien HE, Hall LS, Pardiñas AF, O'Donovan MC, Owen MJ, Anney R. Novel Insight Into the Etiology of Autism Spectrum Disorder Gained by Integrating Expression Data With Genome-wide Association Statistics. Biological Psychiatry. PMID 31230729 DOI: 10.1016/J.Biopsych.2019.04.034  0.341
2019 Richards AL, Pardiñas AF, Frizzati A, Tansey KE, Lynham AJ, Holmans P, Legge SE, Savage JE, Agartz I, Andreassen OA, Blokland GAM, Corvin A, Cosgrove D, Degenhardt F, Djurovic S, ... ... Owen MJ, et al. The Relationship Between Polygenic Risk Scores and Cognition in Schizophrenia. Schizophrenia Bulletin. PMID 31206164 DOI: 10.1093/Schbul/Sbz061  0.366
2019 Mullins N, Bigdeli TB, Børglum AD, Coleman JRI, Demontis D, Mehta D, Power RA, Ripke S, Stahl EA, Starnawska A, Anjorin A, Corvin A, Sanders AR, Forstner AJ, ... ... Owen MJ, et al. GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores. The American Journal of Psychiatry. appiajp201918080957. PMID 31164008 DOI: 10.1176/Appi.Ajp.2019.18080957  0.353
2019 Pardiñas AF, Holmans P, Pocklington AJ, Escott-Price V, Ripke S, Carrera N, Legge SE, Bishop S, Cameron D, Hamshere ML, Han J, Hubbard L, Lynham A, Mantripragada K, Rees E, ... ... Owen MJ, et al. Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection. Nature Genetics. PMID 31160808 DOI: 10.1038/S41588-019-0450-7  0.348
2019 Huckins LM, Dobbyn A, Ruderfer DM, Hoffman G, Wang W, Pardiñas AF, Rajagopal VM, Als TD, T Nguyen H, Girdhar K, Boocock J, Roussos P, Fromer M, Kramer R, Domenici E, ... ... Owen MJ, et al. Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk. Nature Genetics. PMID 31086353 DOI: 10.1038/S41588-019-0435-6  0.342
2019 Chawner SJRA, Owen MJ, Holmans P, Raymond FL, Skuse D, Hall J, van den Bree MBM. Genotype-phenotype associations in children with copy number variants associated with high neuropsychiatric risk in the UK (IMAGINE-ID): a case-control cohort study. The Lancet. Psychiatry. PMID 31056457 DOI: 10.1016/S2215-0366(19)30123-3  0.376
2019 Stahl EA, Breen G, Forstner AJ, McQuillin A, Ripke S, Trubetskoy V, Mattheisen M, Wang Y, Coleman JRI, Gaspar HA, de Leeuw CA, Steinberg S, Pavlides JMW, Trzaskowski M, Byrne EM, ... ... Owen MJ, et al. Genome-wide association study identifies 30 loci associated with bipolar disorder. Nature Genetics. PMID 31043756 DOI: 10.1038/S41588-019-0397-8  0.408
2019 Smeeth DM, Dima D, Jones L, Jones I, Craddock N, Owen MJ, Rietschel M, Maier W, Korszun A, Rice JP, Mors O, Preisig M, Uher R, Lewis CM, Thuret S, et al. Polygenic risk for circulating reproductive hormone levels and their influence on hippocampal volume and depression susceptibility. Psychoneuroendocrinology. 106: 284-292. PMID 31039525 DOI: 10.1016/J.Psyneuen.2019.04.011  0.301
2019 Zhang X, Abdellaoui A, Rucker J, de Jong S, Potash JB, Weissman MM, Shi J, Knowles JA, Pato C, Pato M, Sobell J, Smit JH, Hottenga JJ, de Geus EJC, Lewis CM, ... ... Owen MJ, et al. Genome-wide Burden of Rare Short Deletions Is Enriched in Major Depressive Disorder in Four Cohorts. Biological Psychiatry. PMID 31003785 DOI: 10.1016/J.Biopsych.2019.02.022  0.345
2019 Kendall KM, Rees E, Bracher-Smith M, Legge S, Riglin L, Zammit S, O'Donovan MC, Owen MJ, Jones I, Kirov G, Walters JTR. Association of Rare Copy Number Variants With Risk of Depression. Jama Psychiatry. PMID 30994872 DOI: 10.1001/Jamapsychiatry.2019.0566  0.338
2019 Pardiñas AF, Nalmpanti M, Pocklington AJ, Legge SE, Medway C, King A, Jansen J, Helthuis M, Zammit S, MacCabe J, Owen MJ, O'Donovan MC, Walters JTR. Pharmacogenomic Variants and Drug Interactions Identified Through the Genetic Analysis of Clozapine Metabolism. The American Journal of Psychiatry. appiajp201918050589. PMID 30922102 DOI: 10.1176/Appi.Ajp.2019.18050589  0.363
2019 Huckins LM, Dobbyn A, Ruderfer DM, Hoffman G, Wang W, Pardiñas AF, Rajagopal VM, Als TD, T Nguyen H, Girdhar K, Boocock J, Roussos P, Fromer M, Kramer R, Domenici E, ... ... Owen MJ, et al. Gene expression imputation across multiple brain regions provides insights into schizophrenia risk. Nature Genetics. PMID 30911161 DOI: 10.1038/S41588-019-0364-4  0.412
2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Owen MJ, et al. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. 51: 414-430. PMID 30820047 DOI: 10.1038/s41588-019-0358-2  0.785
2019 Drakesmith M, Parker GD, Smith J, Linden SC, Rees E, Williams N, Owen MJ, van den Bree M, Hall J, Jones DK, Linden DEJ. Genetic risk for schizophrenia and developmental delay is associated with shape and microstructure of midline white-matter structures. Translational Psychiatry. 9: 102. PMID 30804328 DOI: 10.1038/S41398-019-0440-7  0.391
2019 Harold D, Connolly S, Riley BP, Kendler KS, McCarthy SE, McCombie WR, Richards A, Owen MJ, O'Donovan MC, Walters J, Donohoe G, Gill M, Corvin A, et al. Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 30801977 DOI: 10.1002/Ajmg.B.32716  0.395
2019 Kendall KM, Bracher-Smith M, Fitzpatrick H, Lynham A, Rees E, Escott-Price V, Owen MJ, O'Donovan MC, Walters JTR, Kirov G. Cognitive performance and functional outcomes of carriers of pathogenic copy number variants: analysis of the UK Biobank. The British Journal of Psychiatry : the Journal of Mental Science. 1-8. PMID 30767844 DOI: 10.1192/Bjp.2018.301  0.356
2019 Clifton NE, Hannon E, Harwood JC, Di Florio A, Thomas KL, Holmans PA, Walters JTR, O'Donovan MC, Owen MJ, Pocklington AJ, Hall J. Dynamic expression of genes associated with schizophrenia and bipolar disorder across development. Translational Psychiatry. 9: 74. PMID 30718481 DOI: 10.1038/S41398-019-0405-X  0.413
2019 Niarchou M, Chawner SJRA, Doherty JL, Maillard AM, Jacquemont S, Chung WK, Green-Snyder L, Bernier RA, Goin-Kochel RP, Hanson E, Linden DEJ, Linden SC, Raymond FL, Skuse D, Hall J, ... Owen MJ, et al. Psychiatric disorders in children with 16p11.2 deletion and duplication. Translational Psychiatry. 9: 8. PMID 30664628 DOI: 10.1038/S41398-018-0339-8  0.34
2019 Legge SE, Pardiñas AF, Helthuis M, Jansen JA, Jollie K, Knapper S, MacCabe JH, Rujescu D, Collier DA, O'Donovan MC, Owen MJ, Walters JTR. A genome-wide association study in individuals of African ancestry reveals the importance of the Duffy-null genotype in the assessment of clozapine-related neutropenia. Molecular Psychiatry. PMID 30647433 DOI: 10.1038/S41380-018-0335-7  0.402
2019 Escott-Price V, Bracher-Smith M, Menzies G, Walters J, Kirov G, Owen MJ, O'Donovan MC. Genetic liability to schizophrenia is negatively associated with educational attainment in UK Biobank. Molecular Psychiatry. PMID 30610204 DOI: 10.1038/S41380-018-0328-6  0.342
2019 Hubert J, Pardiñas AF, Richards A, Legge S, Lynham A, Pocklington AJ, Owen M, O'Donovan MC, Walters JTR, Escott-Price V. Su25Using Polygenic Risk Score Approaches To Investigate The Common-Variant Genetic Architecture Of Cognition In Schizophrenia European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2018.08.389  0.304
2019 Legge S, Pardiñas AF, Helthuis M, Jansen JA, Jollie K, Knapper S, MacCabe JH, Rujescu D, Collier DA, O'Donovan MC, Owen MJ, Walters JTR. The Impact Of The Duffy-Null Genotype In Clozapine-Associated Neutropenia: A Genome-Wide Association Study In Individuals Of African Ancestry European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2018.07.023  0.354
2019 Kaneva R, Popov I, Beltcheva O, Penchev M, Dzebir G, Rees E, Bozhilova R, Stoyanova V, Mitev V, Owen M, O'Donovan M, Kirov G, Milanova V. Targeted Next Generation Sequencing Of 187 Genes In A Bulgarian Psychosis Sample European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2017.08.214  0.404
2019 Rees E, Carrera N, Morgan J, Pocklington A, Escott-Price V, Kirov G, Holmans P, Walters JTR, Owen M, O'Donovan M. Targeted Sequencing Of 187 Putative Schizophrenia Risk Genes In 5,207 Cases And 4,991 Controls European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2017.08.171  0.35
2019 Leonenko G, Florio AD, Allardyce J, Forty L, Knott S, Jones L, Gordon-Smith K, Craddock N, Owen M, O'Donovan M, Walters J, Jones I, Escott-Price V. Sparse Canonical Correlation In Application To Bipolar Psychotic Phenotypes And Schizophrenia Genome-Wide Significant Genetic Loci European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2017.08.098  0.389
2019 Chawner S, Doherty J, Moss H, Bearden C, Chung W, Curran S, Hall J, Jacquemont S, Kates W, Vorstman J, Owen M, Van Den Bree M. A GENETIC FIRST APPROACH TO DISSECTING THE HETEROGENEITY OF AUTISM: PHENOTYPIC COMPARISON OF AUTISM RISK COPY NUMBER VARIANTS European Neuropsychopharmacology. 29: S783-S784. DOI: 10.1016/J.Euroneuro.2017.08.008  0.332
2019 Pardiñas A, Holmans P, Pocklington A, Escott-Price V, Santiago E, Caballero A, Legge S, Bishop S, Lynham A, O'Donovan M, Owen M, Walters JTR. Evaluating Natural Selection In Schizophrenia Using Data From Genome-Wide Association Studies European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2017.06.101  0.357
2019 Donohoe G, Cosgrove D, Motherills D, Harold D, Kelly S, Holleran L, Holland J, Anney R, Richards A, Owen M, O'Donovan M, Gill M, Corvin A, Morris D. Genetic Risk Variants Interacting With MIR137: Effects On Cognition, Brain Structure And Brain Function In Patients And Healthy Participants European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2017.06.051  0.318
2019 Aaboud M, Aad G, Abbott B, Abdinov O, Abeloos B, Abidi SH, AbouZeid OS, Abraham NL, Abramowicz H, Abreu H, Abreu R, Abulaiti Y, Acharya BS, Adachi S, Adamczyk L, ... Owen M, et al. Erratum to: Search for supersymmetry in final states with two same-sign or three leptons and jets using 36 fb −1 of s$$ \sqrt{s} $$ = 13 TeV pp collision data with the ATLAS detector Journal of High Energy Physics. 2019: 1-19. DOI: 10.1007/Jhep08(2019)121  0.305
2018 Chapman RM, Tinsley CL, Hill MJ, Forrest MP, Tansey KE, Pardiñas AF, Rees E, Doyle AM, Wilkinson LS, Owen MJ, O'Donovan MC, Blake DJ. Convergent Evidence That ZNF804A Is a Regulator of Pre-messenger RNA Processing and Gene Expression. Schizophrenia Bulletin. PMID 30597088 DOI: 10.1093/Schbul/Sby183  0.373
2018 Silva AI, Ulfarsson MO, Stefansson H, Gustafsson O, Walters GB, Linden DEJ, Wilkinson LS, Drakesmith M, Owen MJ, Hall J, Stefansson K. Reciprocal White Matter Changes Associated With Copy Number Variation at 15q11.2 BP1-BP2: A Diffusion Tensor Imaging Study. Biological Psychiatry. PMID 30583851 DOI: 10.1016/J.Biopsych.2018.11.004  0.307
2018 Li M, Santpere G, Imamura Kawasawa Y, Evgrafov OV, Gulden FO, Pochareddy S, Sunkin SM, Li Z, Shin Y, Zhu Y, Sousa AMM, Werling DM, Kitchen RR, Kang HJ, Pletikos M, ... ... Owen MJ, et al. Integrative functional genomic analysis of human brain development and neuropsychiatric risks. Science (New York, N.Y.). 362. PMID 30545854 DOI: 10.1126/Science.Aat7615  0.332
2018 Vivian-Griffiths T, Baker E, Schmidt KM, Bracher-Smith M, Walters J, Artemiou A, Holmans P, O'Donovan MC, Owen MJ, Pocklington A, Escott-Price V. Predictive modeling of schizophrenia from genomic data: Comparison of polygenic risk score with kernel support vector machines approach. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 30516002 DOI: 10.1002/Ajmg.B.32705  0.324
2018 Owen D, Bracher-Smith M, Kendall KM, Rees E, Einon M, Escott-Price V, Owen MJ, O'Donovan MC, Kirov G. Effects of pathogenic CNVs on physical traits in participants of the UK Biobank. Bmc Genomics. 19: 867. PMID 30509170 DOI: 10.1186/S12864-018-5292-7  0.31
2018 Chawner SJRA, Niarchou M, Doherty JL, Moss H, Owen MJ, van den Bree MBM. The emergence of psychotic experiences in the early adolescence of 22q11.2 Deletion Syndrome. Journal of Psychiatric Research. 109: 10-17. PMID 30458299 DOI: 10.1016/J.Jpsychires.2018.11.002  0.304
2018 Rees E, Carrera N, Morgan J, Hambridge K, Escott-Price V, Pocklington AJ, Richards AL, Pardiñas AF, McDonald C, Donohoe G, Morris DW, Kenny E, Kelleher E, Gill M, ... ... Owen MJ, et al. Targeted Sequencing of 10,198 Samples Confirms Abnormalities in Neuronal Activity and Implicates Voltage-Gated Sodium Channels in Schizophrenia Pathogenesis. Biological Psychiatry. PMID 30420267 DOI: 10.1016/J.Biopsych.2018.08.022  0.337
2018 O'Brien HE, Hannon E, Hill MJ, Toste CC, Robertson MJ, Morgan JE, McLaughlin G, Lewis CM, Schalkwyk LC, Hall LS, Pardiñas AF, Owen MJ, O'Donovan MC, Mill J, Bray NJ. Expression quantitative trait loci in the developing human brain and their enrichment in neuropsychiatric disorders. Genome Biology. 19: 194. PMID 30419947 DOI: 10.1186/S13059-018-1567-1  0.31
2018 Sykes L, Haddon J, Lancaster TM, Sykes A, Azzouni K, Ihssen N, Moon AL, Lin TE, Linden DE, Owen MJ, O'Donovan MC, Humby T, Wilkinson LS, Thomas KL, Hall J. Genetic Variation in the Psychiatric Risk Gene CACNA1C Modulates Reversal Learning Across Species. Schizophrenia Bulletin. PMID 30304534 DOI: 10.1093/Schbul/Sby146  0.395
2018 Zhao Y, Guo T, Fiksinski A, Breetvelt E, McDonald-McGinn DM, Crowley TB, Diacou A, Schneider M, Eliez S, Swillen A, Breckpot J, Vermeesch J, Chow EWC, Gothelf D, Duijff S, ... ... Owen M, et al. Variance of IQ is partially dependent on deletion type among 1,427 22q11.2 deletion syndrome subjects. American Journal of Medical Genetics. Part A. PMID 30289625 DOI: 10.1002/Ajmg.A.40359  0.346
2018 Niarchou M, Chawner SJRA, Fiksinski A, Vorstman JAS, Maeder J, Schneider M, Eliez S, Armando M, Pontillo M, Vicari S, McDonald-McGinn DM, Emanuel BS, Zackai EH, Bearden CE, Shashi V, ... ... Owen MJ, et al. Attention deficit hyperactivity disorder symptoms as antecedents of later psychotic outcomes in 22q11.2 deletion syndrome. Schizophrenia Research. PMID 30093352 DOI: 10.1016/J.Schres.2018.07.044  0.311
2018 Jones HJ, Heron J, Hammerton G, Stochl J, Jones PB, Cannon M, Smith GD, Holmans P, Lewis G, Linden DEJ, O'Donovan MC, Owen MJ, Walters J, Zammit S. Investigating the genetic architecture of general and specific psychopathology in adolescence. Translational Psychiatry. 8: 145. PMID 30089819 DOI: 10.1038/S41398-018-0204-9  0.387
2018 Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, ... ... Owen MJ, et al. Analysis of shared heritability in common disorders of the brain. Science (New York, N.Y.). 360. PMID 29930110 DOI: 10.1126/Science.Aap8757  0.625
2018 Sun D, Ching CRK, Lin A, Forsyth JK, Kushan L, Vajdi A, Jalbrzikowski M, Hansen L, Villalon-Reina JE, Qu X, Jonas RK, van Amelsvoort T, Bakker G, Kates WR, Antshel KM, ... ... Owen MJ, et al. Large-scale mapping of cortical alterations in 22q11.2 deletion syndrome: Convergence with idiopathic psychosis and effects of deletion size. Molecular Psychiatry. PMID 29895892 DOI: 10.1038/S41380-018-0078-5  0.357
2018 Skene NG, Bryois J, Bakken TE, Breen G, Crowley JJ, Gaspar HA, Giusti-Rodriguez P, Hodge RD, Miller JA, Muñoz-Manchado AB, O'Donovan MC, Owen MJ, Pardiñas AF, Ryge J, Walters JTR, et al. Genetic identification of brain cell types underlying schizophrenia. Nature Genetics. PMID 29785013 DOI: 10.1038/s41588-018-0129-5  0.374
2018 Wray NR, Ripke S, Mattheisen M, Trzaskowski M, Byrne EM, Abdellaoui A, Adams MJ, Agerbo E, Air TM, Andlauer TMF, Bacanu SA, Bækvad-Hansen M, Beekman AFT, Bigdeli TB, Binder EB, ... ... Owen MJ, et al. Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. Nature Genetics. PMID 29700475 DOI: 10.1038/S41588-018-0090-3  0.357
2018 Guyatt AL, Stergiakouli E, Martin J, Walters J, O'Donovan M, Owen M, Thapar A, Kirov G, Rodriguez S, Rai D, Zammit S, Gaunt TR. Association of copy number variation across the genome with neuropsychiatric traits in the general population. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 29687944 DOI: 10.1002/Ajmg.B.32637  0.404
2018 Leonenko G, Di Florio A, Allardyce J, Forty L, Knott S, Jones L, Gordon-Smith K, Owen MJ, Jones I, Walters J, Craddock N, O'Donovan MC, Escott-Price V. A data-driven investigation of relationships between bipolar psychotic symptoms and schizophrenia genome-wide significant genetic loci. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 29671935 DOI: 10.1002/Ajmg.B.32635  0.435
2018 Lynham AJ, Hubbard L, Tansey KE, Hamshere ML, Legge SE, Owen MJ, Jones IR, Walters JTR. Examining cognition across the bipolar/schizophrenia diagnostic spectrum. Journal of Psychiatry & Neuroscience : Jpn. 43: 170076. PMID 29620518 DOI: 10.1016/S0924-977X(17)31336-6  0.333
2018 Lancaster TM, Dimitriadis SL, Tansey KE, Perry G, Ihssen N, Jones DK, Singh KD, Holmans P, Pocklington A, Davey Smith G, Zammit S, Hall J, O'Donovan MC, Owen MJ, Linden DE. Structural and Functional Neuroimaging of Polygenic Risk for Schizophrenia: A Recall-by-Genotype-Based Approach. Schizophrenia Bulletin. PMID 29608775 DOI: 10.1093/Schbul/Sby037  0.357
2018 Escott-Price V, Smith DJ, Kendall K, Ward J, Kirov G, Owen MJ, Walters J, O'Donovan MC. Polygenic risk for schizophrenia and season of birth within the UK Biobank cohort. Psychological Medicine. 1-6. PMID 29501066 DOI: 10.1017/S0033291718000454  0.324
2018 Pardiñas AF, Holmans P, Pocklington AJ, Escott-Price V, Ripke S, Carrera N, Legge SE, Bishop S, Cameron D, Hamshere ML, Han J, Hubbard L, Lynham A, Mantripragada K, Rees E, ... ... Owen MJ, et al. Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection. Nature Genetics. PMID 29483656 DOI: 10.1038/S41588-018-0059-2  0.435
2018 Corbin LJ, Tan VY, Hughes DA, Wade KH, Paul DS, Tansey KE, Butcher F, Dudbridge F, Howson JM, Jallow MW, John C, Kingston N, Lindgren CM, O'Donavan M, O'Rahilly S, ... Owen MJ, et al. Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference. Nature Communications. 9: 711. PMID 29459775 DOI: 10.1038/S41467-018-03109-Y  0.347
2018 Cunningham AC, Delport S, Cumines W, Busse M, Linden DEJ, Hall J, Owen MJ, van den Bree MBM. Developmental coordination disorder, psychopathology and IQ in 22q11.2 deletion syndrome. The British Journal of Psychiatry : the Journal of Mental Science. 212: 27-33. PMID 29433607 DOI: 10.1192/Bjp.2017.6  0.316
2018 Cosgrove D, Mothersill DO, Whitton L, Harold D, Kelly S, Holleran L, Holland J, Anney R, Richards A, Mantripragada K, Owen M, O'Donovan MC, Gill M, Corvin A, et al. Effects of MiR-137 genetic risk score on brain volume and cortical measures in patients with schizophrenia and controls. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 29418072 DOI: 10.1002/Ajmg.B.32620  0.321
2018 Lloyd K, John A, Craddock N, Walters J, Linden D, Jones I, Bentall R, Lyons R, Lee SC, Owen M. A National Population-Based E-cohort of People with Psychosis (PsyCymru) Linkage of Phenotypical and Genetic Data to Routinely Collected Records International Journal of Population Data Science. 3. DOI: 10.23889/Ijpds.V3I4.706  0.332
2018 Owen M. 9. Does Biology Read The Dsm? Transdiagnostic Findings In Psychosis And Implications For Treatment. Schizophrenia Bulletin. 44. DOI: 10.1093/Schbul/Sby014.028  0.318
2017 Allardyce J, Leonenko G, Hamshere M, Pardiñas AF, Forty L, Knott S, Gordon-Smith K, Porteous DJ, Haywood C, Di Florio A, Jones L, McIntosh AM, Owen MJ, Holmans P, Walters JTR, et al. Association Between Schizophrenia-Related Polygenic Liability and the Occurrence and Level of Mood-Incongruent Psychotic Symptoms in Bipolar Disorder. Jama Psychiatry. PMID 29167880 DOI: 10.1001/Jamapsychiatry.2017.3485  0.388
2017 Owen MJ, O'Donovan MC. Schizophrenia and the neurodevelopmental continuum:evidence from genomics. World Psychiatry : Official Journal of the World Psychiatric Association (Wpa). 16: 227-235. PMID 28941101 DOI: 10.1002/Wps.20440  0.373
2017 Chawner SJRA, Doherty JL, Moss H, Niarchou M, Walters JTR, Owen MJ, van den Bree MBM. Childhood cognitive development in 22q11.2 deletion syndrome: case-control study. The British Journal of Psychiatry : the Journal of Mental Science. PMID 28882829 DOI: 10.1192/Bjp.Bp.116.195651  0.307
2017 Cohen-Woods S, Fisher HL, Ahmetspahic D, Douroudis K, Stacey D, Hosang GM, Korszun A, Owen M, Craddock N, Arolt V, Dannowski U, Breen G, Craig IW, Farmer A, Baune BT, et al. Interaction between childhood maltreatment on immunogenetic risk in depression: discovery and replication in clinical case-control samples. Brain, Behavior, and Immunity. PMID 28867280 DOI: 10.1016/J.Bbi.2017.08.023  0.349
2017 Green EK, Di Florio A, Forty L, Gordon-Smith K, Grozeva D, Fraser C, Richards AL, Moran JL, Purcell S, Sklar P, Kirov G, Owen MJ, O'Donovan MC, Craddock N, Jones L, et al. Genome-wide significant locus for Research Diagnostic Criteria Schizoaffective Disorder Bipolar type. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 28851079 DOI: 10.1002/Ajmg.B.32572  0.413
2017 Bassett AS, Lowther C, Merico D, Costain G, Chow EWC, van Amelsvoort T, McDonald-McGinn D, Gur RE, Swillen A, Van den Bree M, Murphy K, Gothelf D, Bearden CE, Eliez S, Kates W, ... ... Owen M, et al. Rare Genome-Wide Copy Number Variation and Expression of Schizophrenia in 22q11.2 Deletion Syndrome. The American Journal of Psychiatry. appiajp201716121417. PMID 28750581 DOI: 10.1176/Appi.Ajp.2017.16121417  0.317
2017 Leonenko G, Richards AL, Walters JT, Pocklington A, Chambert K, Al Eissa MM, Sharp SI, O'Brien NL, Curtis D, Bass NJ, McQuillin A, Hultman C, Moran JL, McCarroll SA, Sklar P, ... ... Owen MJ, et al. Mutation intolerant genes and targets of FMRP are enriched for nonsynonymous alleles in schizophrenia. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 28719003 DOI: 10.1002/Ajmg.B.32560  0.423
2017 Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, ... ... Owen MJ, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics. PMID 28714976 DOI: 10.1038/Ng.3916  0.778
2017 Singh T, Walters JTR, Johnstone M, Curtis D, Suvisaari J, Torniainen M, Rees E, Iyegbe C, Blackwood D, McIntosh AM, Kirov G, Geschwind D, Murray RM, Di Forti M, Bramon E, ... ... Owen MJ, et al. The contribution of rare variants to risk of schizophrenia in individuals with and without intellectual disability. Nature Genetics. PMID 28650482 DOI: 10.1038/Ng.3903  0.414
2017 Cosgrove D, Mothersill O, Kendall K, Konte B, Harold D, Giegling I, Hartmann A, Richards A, Mantripragada K, Owen MJ, O'Donovan MC, Gill M, Rujescu D, Walters J, Corvin A, et al. Cognitive Characterization of Schizophrenia Risk Variants Involved in Synaptic Transmission: Evidence of CACNA1C's Role in Working Memory. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28607492 DOI: 10.1038/Npp.2017.123  0.399
2017 Bigdeli TB, Ripke S, Peterson RE, Trzaskowski M, Bacanu SA, Abdellaoui A, Andlauer TF, Beekman AT, Berger K, Blackwood DH, Boomsma DI, Breen G, Buttenschøn HN, Byrne EM, Cichon S, ... ... Owen MJ, et al. Genetic effects influencing risk for major depressive disorder in China and Europe. Translational Psychiatry. 7: e1074. PMID 28350396 DOI: 10.1038/Tp.2016.292  0.411
2017 Cosgrove D, Harold D, Mothersill O, Anney R, Hill MJ, Bray NJ, Blokland G, Petryshen T, Richards A, Mantripragada K, Owen M, O'Donovan MC, Gill M, Corvin A, et al. MiR-137-derived polygenic risk: effects on cognitive performance in patients with schizophrenia and controls. Translational Psychiatry. 7: e1012. PMID 28117840 DOI: 10.1038/Tp.2016.286  0.359
2017 Giegling I, Hosak L, Mössner R, Serretti A, Bellivier F, Claes S, Collier DA, Corrales A, DeLisi LE, Gallo C, Gill M, Kennedy JL, Leboyer M, Maier W, Marquez M, ... ... Owen MJ, et al. Genetics of schizophrenia: A consensus paper of the WFSBP Task Force on Genetics. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 1-14. PMID 28112043 DOI: 10.1080/15622975.2016.1268715  0.386
2017 Kirov G, Kendall K, Rees E, Escott-Price V, Hewitt J, Thomas R, O'Donovan M, Owen M, Walters J. The Uk Biobank: A Resource For Cnv Analysis European Neuropsychopharmacology. 27. DOI: 10.1016/J.Euroneuro.2016.09.584  0.305
2017 Allardyce J, Leonenko G, Hamshere M, Knott S, Forty L, Jones L, Smith KG, Owen M, Craddock N, O'Donovan M, Jones I, Escott-Price V. Polygenic Risk Scores Derived From Largest Schizophrenia Gwas Are Associated With The Presence Of Psychosis And Level Of Mood Incongruent Psychosis In Bipolar Disorder European Neuropsychopharmacology. 27. DOI: 10.1016/J.Euroneuro.2016.09.511  0.369
2017 Leonenko G, Allardyce J, Forty L, Knott S, Craddock N, Owen MJ, O'Donovan MC, Jones I, Escott-Price V. Investigation of Relationships Between Bipolar Disorder Phenotypes And Genome-Wide Significant Loci From PGC2 Schizophrenia European Neuropsychopharmacology. 27. DOI: 10.1016/J.Euroneuro.2016.09.416  0.374
2016 Clifton NE, Pocklington AJ, Scholz B, Rees E, Walters JT, Kirov G, O'Donovan MC, Owen MJ, Wilkinson LS, Thomas KL, Hall J. Schizophrenia copy number variants and associative learning. Molecular Psychiatry. PMID 27956746 DOI: 10.1038/Mp.2016.227  0.408
2016 O'Donovan MC, Owen MJ. The implications of the shared genetics of psychiatric disorders. Nature Medicine. 22: 1214-1219. PMID 27783064 DOI: 10.1038/Nm.4196  0.38
2016 Kendall KM, Rees E, Escott-Price V, Einon M, Thomas R, Hewitt J, O'Donovan MC, Owen MJ, Walters JT, Kirov G. Cognitive Performance Among Carriers of Pathogenic Copy Number Variants: Analysis of 152,000 UK Biobank Subjects. Biological Psychiatry. PMID 27773354 DOI: 10.1016/J.Biopsych.2016.08.014  0.3
2016 Whitton L, Cosgrove D, Clarkson C, Harold D, Kendall K, Richards A, Mantripragada K, Owen MJ, O'Donovan MC, Walters J, Hartmann A, Konte B, Rujescu D, Gill M, et al. Cognitive analysis of schizophrenia risk genes that function as epigenetic regulators of gene expression. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 27762073 DOI: 10.1002/Ajmg.B.32503  0.42
2016 Howes OD, McCutcheon R, Owen MJ, Murray RM. The Role of Genes, Stress, and Dopamine in the Development of Schizophrenia. Biological Psychiatry. PMID 27720198 DOI: 10.1016/J.Biopsych.2016.07.014  0.328
2016 Rees E, Kendall K, Pardiñas AF, Legge SE, Pocklington A, Escott-Price V, MacCabe JH, Collier DA, Holmans P, O'Donovan MC, Owen MJ, Walters JT, Kirov G. Analysis of Intellectual Disability Copy Number Variants for Association With Schizophrenia. Jama Psychiatry. 73: 963-9. PMID 27602560 DOI: 10.1001/Jamapsychiatry.2016.1831  0.387
2016 Power RA, Tansey KE, Buttenschøn HN, Cohen-Woods S, Bigdeli T, Hall LS, Kutalik Z, Lee SH, Ripke S, Steinberg S, Teumer A, Viktorin A, Wray NR, Arolt V, Baune BT, ... ... Owen MJ, et al. Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Biological Psychiatry. PMID 27519822 DOI: 10.1016/J.Biopsych.2016.05.010  0.35
2016 Legge SE, Hamshere ML, Ripke S, Pardinas AF, Goldstein JI, Rees E, Richards AL, Leonenko G, Jorskog LF, Chambert KD, Collier DA, Genovese G, Giegling I, Holmans P, ... ... Owen MJ, et al. Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia. Molecular Psychiatry. PMID 27400856 DOI: 10.1038/Mp.2016.97  0.319
2016 Han J, Walters JT, Kirov G, Pocklington A, Escott-Price V, Owen MJ, Holmans P, O'Donovan MC, Rees E. Gender differences in CNV burden do not confound schizophrenia CNV associations. Scientific Reports. 6: 25986. PMID 27185616 DOI: 10.1038/Srep25986  0.365
2016 Isles AR, Ingason A, Lowther C, Walters J, Gawlick M, Stöber G, Rees E, Martin J, Little RB, Potter H, Georgieva L, Pizzo L, Ozaki N, Aleksic B, Kushima I, ... ... Owen MJ, et al. Parental Origin of Interstitial Duplications at 15q11.2-q13.3 in Schizophrenia and Neurodevelopmental Disorders. Plos Genetics. 12: e1005993. PMID 27153221 DOI: 10.1371/Journal.Pgen.1005993  0.35
2016 Fry AE, Rees E, Thompson R, Mantripragada K, Blake P, Jones G, Morgan S, Jose S, Mugalaasi H, Archer H, McCann E, Clarke A, Taylor C, Davies S, Gibbon F, ... ... Owen MJ, et al. Pathogenic copy number variants and SCN1A mutations in patients with intellectual disability and childhood-onset epilepsy. Bmc Medical Genetics. 17: 34. PMID 27113213 DOI: 10.1186/S12881-016-0294-2  0.303
2016 Walters JT, Owen MJ. Genome-wide Significant Associations for Cannabis Dependence Severity: Relevance to Psychiatric Disorders. Jama Psychiatry. PMID 27027914 DOI: 10.1001/Jamapsychiatry.2016.0046  0.335
2016 Singh T, Kurki MI, Curtis D, Purcell SM, Crooks L, McRae J, Suvisaari J, Chheda H, Blackwood D, Breen G, Pietiläinen O, Gerety SS, Ayub M, Blyth M, Cole T, ... ... Owen MJ, et al. Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders. Nature Neuroscience. PMID 26974950 DOI: 10.1038/Nn.4267  0.418
2016 Millan MJ, Andrieux A, Bartzokis G, Cadenhead K, Dazzan P, Fusar-Poli P, Gallinat J, Giedd J, Grayson DR, Heinrichs M, Kahn R, Krebs MO, Leboyer M, Lewis D, Marin O, ... ... Owen MJ, et al. Altering the course of schizophrenia: progress and perspectives. Nature Reviews. Drug Discovery. PMID 26939910 DOI: 10.1038/Nrd.2016.28  0.365
2016 Owen MJ, Doherty JL. What can we learn from the high rates of schizophrenia in people with 22q11.2 deletion syndrome? World Psychiatry : Official Journal of the World Psychiatric Association (Wpa). 15: 23-5. PMID 26833600 DOI: 10.1002/Wps.20274  0.321
2016 Jones HJ, Stergiakouli E, Tansey KE, Hubbard L, Heron J, Cannon M, Holmans P, Lewis G, Linden DE, Jones PB, Davey Smith G, O'Donovan MC, Owen MJ, Walters JT, Zammit S. Phenotypic Manifestation of Genetic Risk for Schizophrenia During Adolescence in the General Population. Jama Psychiatry. PMID 26818099 DOI: 10.1001/Jamapsychiatry.2015.3058  0.364
2016 Peall KJ, Dijk JM, Saunders-Pullman R, Dreissen YE, van Loon I, Cath D, Kurian MA, Owen MJ, Foncke EM, Morris HR, Gasser T, Bressman S, Asmus F, Tijssen MA. Psychiatric disorders, myoclonus dystonia and SGCE: an international study. Annals of Clinical and Translational Neurology. 3: 4-11. PMID 26783545 DOI: 10.1002/Acn3.263  0.307
2016 Richards AL, Leonenko G, Walters JT, Kavanagh DH, Rees EG, Evans A, Chambert KD, Moran JL, Goldstein J, Neale BM, McCarroll SA, Pocklington AJ, Holmans PA, Owen MJ, O'Donovan MC. Exome arrays capture polygenic rare variant contributions to schizophrenia. Human Molecular Genetics. PMID 26740555 DOI: 10.1093/Hmg/Ddv620  0.459
2016 Aaboud M, Kupco A, Davison P, Webb S, Sekula S, Huston J, Jakobs K, Saito T, Spousta M, Slovak R, Cobal M, Agatonovic-Jovin T, Schovancova J, DeMarco D, Laurelli P, ... Owen M, et al. Search for dark matter produced in association with a hadronically decaying vector boson in pp collisions at $\sqrt(s)$=13 TeV with the ATLAS detector Physics Letters B. 763: 251-268. DOI: 10.1016/J.Physletb.2016.10.042  0.305
2015 Hubbard L, Tansey KE, Rai D, Jones P, Ripke S, Chambert KD, Moran JL, McCarroll SA, Linden DE, Owen MJ, O'Donovan MC, Walters JT, Zammit S. Evidence of Common Genetic Overlap Between Schizophrenia and Cognition. Schizophrenia Bulletin. PMID 26678674 DOI: 10.1093/Schbul/Sbv168  0.373
2015 Tansey KE, Rees E, Linden DE, Ripke S, Chambert KD, Moran JL, McCarroll SA, Holmans P, Kirov G, Walters J, Owen MJ, O'Donovan MC. Common alleles contribute to schizophrenia in CNV carriers. Molecular Psychiatry. PMID 26643540 DOI: 10.1038/Mp.2015.170  0.346
2015 Escott-Price V, Kirov G, Rees E, Isles AR, Owen MJ, O'Donovan MC. No Evidence for Enrichment in Schizophrenia for Common Allelic Associations at Imprinted Loci. Plos One. 10: e0144172. PMID 26633303 DOI: 10.1371/Journal.Pone.0144172  0.389
2015 D'Angelo D, Lebon S, Chen Q, Martin-Brevet S, Snyder LG, Hippolyte L, Hanson E, Maillard AM, Faucett WA, Macé A, Pain A, Bernier R, Chawner SJ, David A, Andrieux J, ... ... Owen MJ, et al. Defining the Effect of the 16p11.2 Duplication on Cognition, Behavior, and Medical Comorbidities. Jama Psychiatry. 1-11. PMID 26629640 DOI: 10.1001/Jamapsychiatry.2015.2123  0.343
2015 Thapar A, Martin J, Mick E, Arias Vásquez A, Langley K, Scherer SW, Schachar R, Crosbie J, Williams N, Franke B, Elia J, Glessner J, Hakonarson H, Owen MJ, Faraone SV, et al. Psychiatric gene discoveries shape evidence on ADHD's biology. Molecular Psychiatry. PMID 26573769 DOI: 10.1038/Mp.2015.163  0.395
2015 Carroll LS, Woolf R, Ibrahim Y, Williams HJ, Dwyer S, Walters J, Kirov G, O'Donovan MC, Owen MJ. Mutation screening of SCN2A in schizophrenia and identification of a novel loss-of-function mutation. Psychiatric Genetics. PMID 26555645 DOI: 10.1097/Ypg.0000000000000110  0.352
2015 Mullins N, Power RA, Fisher HL, Hanscombe KB, Euesden J, Iniesta R, Levinson DF, Weissman MM, Potash JB, Shi J, Uher R, Cohen-Woods S, Rivera M, Jones L, Jones I, ... ... Owen MJ, et al. Polygenic interactions with environmental adversity in the aetiology of major depressive disorder. Psychological Medicine. 1-12. PMID 26526099 DOI: 10.1017/S0033291715002172  0.31
2015 Lancaster TM, Ihssen N, Brindley LM, Tansey KE, Mantripragada K, O'Donovan MC, Owen MJ, Linden DE. Associations between polygenic risk for schizophrenia and brain function during probabilistic learning in healthy individuals. Human Brain Mapping. PMID 26510167 DOI: 10.1002/Hbm.23044  0.364
2015 Tansey KE, Rees E, Linden DE, Ripke S, Chambert KD, Moran JL, McCarroll SA, Holmans P, Kirov G, Walters J, Owen MJ, O'Donovan MC. Common alleles contribute to schizophrenia in CNV carriers. Molecular Psychiatry. PMID 26390827 DOI: 10.1038/Mp.2015.143  0.407
2015 Heyes S, Pratt WS, Rees E, Dahimene S, Ferron L, Owen MJ, Dolphin AC. Genetic disruption of voltage-gated calcium channels in psychiatric and neurological disorders. Progress in Neurobiology. PMID 26386135 DOI: 10.1016/J.Pneurobio.2015.09.002  0.365
2015 Lee SH, Byrne EM, Hultman CM, Kähler A, Vinkhuyzen AA, Ripke S, Andreassen OA, Frisell T, Gusev A, Hu X, Karlsson R, Mantzioris VX, McGrath JJ, Mehta D, Stahl EA, ... ... Owen MJ, et al. New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis. International Journal of Epidemiology. PMID 26286434 DOI: 10.1093/Ije/Dyv136  0.371
2015 Rees E, Kirov G, Walters JT, Richards AL, Howrigan D, Kavanagh DH, Pocklington AJ, Fromer M, Ruderfer DM, Georgieva L, Carrera N, Gormley P, Palta P, Williams H, Dwyer S, ... ... Owen MJ, et al. Analysis of exome sequence in 604 trios for recessive genotypes in schizophrenia. Translational Psychiatry. 5: e607. PMID 26196440 DOI: 10.1038/Tp.2015.99  0.428
2015 Lloyd K, McGregor J, John A, Craddock N, Walters JT, Linden D, Jones I, Bentall R, Lyons RA, Ford DV, Owen MJ. A national population-based e-cohort of people with psychosis (PsyCymru) linking prospectively ascertained phenotypically rich and genetic data to routinely collected records: overview, recruitment and linkage. Schizophrenia Research. 166: 131-6. PMID 26139629 DOI: 10.1016/J.Schres.2015.05.036  0.305
2015 Pocklington AJ, Rees E, Walters JT, Han J, Kavanagh DH, Chambert KD, Holmans P, Moran JL, McCarroll SA, Kirov G, O'Donovan MC, Owen MJ. Novel Findings from CNVs Implicate Inhibitory and Excitatory Signaling Complexes in Schizophrenia. Neuron. 86: 1203-14. PMID 26050040 DOI: 10.1016/J.Neuron.2015.04.022  0.421
2015 Hung CF, Breen G, Czamara D, Corre T, Wolf C, Kloiber S, Bergmann S, Craddock N, Gill M, Holsboer F, Jones L, Jones I, Korszun A, Kutalik Z, Lucae S, ... ... Owen MJ, et al. A genetic risk score combining 32 SNPs is associated with body mass index and improves obesity prediction in people with major depressive disorder. Bmc Medicine. 13: 86. PMID 25903154 DOI: 10.1186/S12916-015-0334-3  0.324
2015 Rucker JJ, Tansey KE, Rivera M, Pinto D, Cohen-Woods S, Uher R, Aitchison KJ, Craddock N, Owen MJ, Jones L, Jones I, Korszun A, Barnes MR, Preisig M, Mors O, et al. Phenotypic Association Analyses with Copy Number Variation in Recurrent Depressive Disorder. Biological Psychiatry. PMID 25861698 DOI: 10.1016/J.Biopsych.2015.02.025  0.31
2015 Oertel-Knöchel V, Lancaster TM, Knöchel C, Stäblein M, Storchak H, Reinke B, Jurcoane A, Kniep J, Prvulovic D, Mantripragada K, Tansey KE, O'Donovan MC, Owen MJ, Linden DE. Schizophrenia risk variants modulate white matter volume across the psychosis spectrum: evidence from two independent cohorts. Neuroimage. Clinical. 7: 764-70. PMID 25844328 DOI: 10.1016/J.Nicl.2015.03.005  0.332
2015 Farrell MS, Werge T, Sklar P, Owen MJ, Ophoff RA, O'Donovan MC, Corvin A, Cichon S, Sullivan PF. Evaluating historical candidate genes for schizophrenia. Molecular Psychiatry. 20: 555-62. PMID 25754081 DOI: 10.1038/Mp.2015.16  0.317
2015 Ferentinos P, Koukounari A, Power R, Rivera M, Uher R, Craddock N, Owen MJ, Korszun A, Jones L, Jones I, Gill M, Rice JP, Ising M, Maier W, Mors O, et al. Familiality and SNP heritability of age at onset and episodicity in major depressive disorder. Psychological Medicine. 1-11. PMID 25698070 DOI: 10.1017/S0033291715000215  0.347
2015 Desikan RS, Schork AJ, Wang Y, Witoelar A, Sharma M, McEvoy LK, Holland D, Brewer JB, Chen CH, Thompson WK, Harold D, Williams J, Owen MJ, O'Donovan MC, Pericak-Vance MA, et al. Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus. Molecular Psychiatry. PMID 25687773 DOI: 10.1038/Mp.2015.6  0.65
2015 Green EK, Rees E, Walters JT, Smith KG, Forty L, Grozeva D, Moran JL, Sklar P, Ripke S, Chambert KD, Genovese G, McCarroll SA, Jones I, Jones L, Owen MJ, et al. Copy number variation in bipolar disorder. Molecular Psychiatry. PMID 25560756 DOI: 10.1038/Mp.2014.174  0.316
2015 Tansey KE, Owen MJ, O'Donovan MC. Schizophrenia genetics: building the foundations of the future. Schizophrenia Bulletin. 41: 15-9. PMID 25394665 DOI: 10.1093/Schbul/Sbu162  0.349
2015 Kavanagh DH, Tansey KE, O'Donovan MC, Owen MJ. Schizophrenia genetics: emerging themes for a complex disorder. Molecular Psychiatry. 20: 72-6. PMID 25385368 DOI: 10.1038/Mp.2014.148  0.312
2015 Hall J, Trent S, Thomas KL, O'Donovan MC, Owen MJ. Genetic risk for schizophrenia: convergence on synaptic pathways involved in plasticity. Biological Psychiatry. 77: 52-8. PMID 25152434 DOI: 10.1016/J.Biopsych.2014.07.011  0.363
2015 Aad G, Abbott B, Abdallah J, Khalek SA, Abdinov O, Aben R, Abi B, Abolins M, AbouZeid OS, Abramowicz H, Abreu H, Abreu R, Abulaiti Y, Acharya BS, Adamczyk L, ... Owen M, et al. Erratum to: Search for new phenomena in final states with an energetic jet and large missing transverse momentum in pp collisions at s=8 TeV with the ATLAS detector European Physical Journal C. 75: 408. DOI: 10.1140/Epjc/S10052-015-3639-7  0.302
2015 Rees E, O'Donovan MC, Owen MJ. Genetics of schizophrenia Current Opinion in Behavioral Sciences. 2: 8-14. DOI: 10.1016/J.Cobeha.2014.07.001  0.438
2014 Lancaster TM, Brindley LM, Tansey KE, Sims RC, Mantripragada K, Owen MJ, Williams J, Linden DE. Alzheimer's disease risk variant in CLU is associated with neural inefficiency in healthy individuals. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 25496871 DOI: 10.1016/J.Jalz.2014.10.012  0.485
2014 Georgieva L, Rees E, Moran JL, Chambert KD, Milanova V, Craddock N, Purcell S, Sklar P, McCarroll S, Holmans P, O'Donovan MC, Owen MJ, Kirov G. De novo CNVs in bipolar affective disorder and schizophrenia. Human Molecular Genetics. 23: 6677-83. PMID 25055870 DOI: 10.1093/Hmg/Ddu379  0.325
2014 Mullins N, Perroud N, Uher R, Butler AW, Cohen-Woods S, Rivera M, Malki K, Euesden J, Power RA, Tansey KE, Jones L, Jones I, Craddock N, Owen MJ, Korszun A, et al. Genetic relationships between suicide attempts, suicidal ideation and major psychiatric disorders: a genome-wide association and polygenic scoring study. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 165: 428-37. PMID 24964207 DOI: 10.1002/Ajmg.B.32247  0.32
2014 Doherty JL, Owen MJ. Genomic insights into the overlap between psychiatric disorders: implications for research and clinical practice. Genome Medicine. 6: 29. PMID 24944580 DOI: 10.1186/Gm546  0.315
2014 Escott-Price V, Bellenguez C, Wang LS, Choi SH, Harold D, Jones L, Holmans P, Gerrish A, Vedernikov A, Richards A, DeStefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R, ... ... Owen MJ, et al. Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease. Plos One. 9: e94661. PMID 24922517 DOI: 10.1371/Journal.Pone.0094661  0.725
2014 Niarchou M, Zammit S, Escott-Price V, Owen MJ, van den Bree MB. Exploring the indirect effects of catechol-O-methyltransferase (COMT) genotype on psychotic experiences through cognitive function and anxiety disorders in a large birth cohort of children. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 165: 410-20. PMID 24862404 DOI: 10.1002/Ajmg.B.32245  0.305
2014 van Os J, Rutten BP, Myin-Germeys I, Delespaul P, Viechtbauer W, van Zelst C, Bruggeman R, Reininghaus U, Morgan C, Murray RM, Di Forti M, McGuire P, Valmaggia LR, Kempton MJ, ... ... Owen MJ, et al. Identifying gene-environment interactions in schizophrenia: contemporary challenges for integrated, large-scale investigations. Schizophrenia Bulletin. 40: 729-36. PMID 24860087 DOI: 10.1093/Schbul/Sbu069  0.316
2014 Szatkiewicz JP, O'Dushlaine C, Chen G, Chambert K, Moran JL, Neale BM, Fromer M, Ruderfer D, Akterin S, Bergen SE, Kähler A, Magnusson PK, Kim Y, Crowley JJ, Rees E, ... ... Owen MJ, et al. Copy number variation in schizophrenia in Sweden. Molecular Psychiatry. 19: 762-73. PMID 24776740 DOI: 10.1038/Mp.2014.40  0.416
2014 Schneider M, Debbané M, Bassett AS, Chow EW, Fung WL, van den Bree M, Owen M, Murphy KC, Niarchou M, Kates WR, Antshel KM, Fremont W, McDonald-McGinn DM, Gur RE, Zackai EH, et al. Psychiatric disorders from childhood to adulthood in 22q11.2 deletion syndrome: results from the International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome. The American Journal of Psychiatry. 171: 627-39. PMID 24577245 DOI: 10.1176/Appi.Ajp.2013.13070864  0.328
2014 Cardno AG, Owen MJ. Genetic relationships between schizophrenia, bipolar disorder, and schizoaffective disorder. Schizophrenia Bulletin. 40: 504-15. PMID 24567502 DOI: 10.1093/Schbul/Sbu016  0.348
2014 Rees E, Walters JT, Georgieva L, Isles AR, Chambert KD, Richards AL, Mahoney-Davies G, Legge SE, Moran JL, McCarroll SA, O'Donovan MC, Owen MJ, Kirov G. Analysis of copy number variations at 15 schizophrenia-associated loci. The British Journal of Psychiatry : the Journal of Mental Science. 204: 108-14. PMID 24311552 DOI: 10.1192/Bjp.Bp.113.131052  0.324
2014 Rees E, Kirov G, Sanders A, Walters JT, Chambert KD, Shi J, Szatkiewicz J, O'Dushlaine C, Richards AL, Green EK, Jones I, Davies G, Legge SE, Moran JL, Pato C, ... ... Owen MJ, et al. Evidence that duplications of 22q11.2 protect against schizophrenia. Molecular Psychiatry. 19: 37-40. PMID 24217254 DOI: 10.1038/Mp.2013.156  0.392
2014 Ferentinos P, Rivera M, Ising M, Spain SL, Cohen-Woods S, Butler AW, Craddock N, Owen MJ, Korszun A, Jones L, Jones I, Gill M, Rice JP, Maier W, Mors O, et al. Investigating the genetic variation underlying episodicity in major depressive disorder: suggestive evidence for a bipolar contribution. Journal of Affective Disorders. 155: 81-9. PMID 24215895 DOI: 10.1016/J.Jad.2013.10.027  0.382
2014 Zammit S, Hamshere M, Dwyer S, Georgiva L, Timpson N, Moskvina V, Richards A, Evans DM, Lewis G, Jones P, Owen MJ, O'Donovan MC. A population-based study of genetic variation and psychotic experiences in adolescents. Schizophrenia Bulletin. 40: 1254-62. PMID 24174267 DOI: 10.1093/Schbul/Sbt146  0.412
2014 Rees E, Walters JT, Chambert KD, O'Dushlaine C, Szatkiewicz J, Richards AL, Georgieva L, Mahoney-Davies G, Legge SE, Moran JL, Genovese G, Levinson D, Morris DW, Cormican P, Kendler KS, ... ... Owen MJ, et al. CNV analysis in a large schizophrenia sample implicates deletions at 16p12.1 and SLC1A1 and duplications at 1p36.33 and CGNL1. Human Molecular Genetics. 23: 1669-76. PMID 24163246 DOI: 10.1093/Hmg/Ddt540  0.424
2014 Kirov G, Rees E, Walters JT, Escott-Price V, Georgieva L, Richards AL, Chambert KD, Davies G, Legge SE, Moran JL, McCarroll SA, O'Donovan MC, Owen MJ. The penetrance of copy number variations for schizophrenia and developmental delay. Biological Psychiatry. 75: 378-85. PMID 23992924 DOI: 10.1016/J.Biopsych.2013.07.022  0.36
2014 Mulle JG, Pulver AE, McGrath JA, Wolyniec PS, Dodd AF, Cutler DJ, Sebat J, Malhotra D, Nestadt G, Conrad DF, Hurles M, Barnes CP, Ikeda M, Iwata N, Levinson DF, ... ... Owen MJ, et al. Reciprocal duplication of the Williams-Beuren syndrome deletion on chromosome 7q11.23 is associated with schizophrenia. Biological Psychiatry. 75: 371-7. PMID 23871472 DOI: 10.1016/J.Biopsych.2013.05.040  0.394
2014 Steinberg S, de Jong S, Mattheisen M, Costas J, Demontis D, Jamain S, Pietiläinen OP, Lin K, Papiol S, Huttenlocher J, Sigurdsson E, Vassos E, Giegling I, Breuer R, Fraser G, ... ... Owen MJ, et al. Common variant at 16p11.2 conferring risk of psychosis. Molecular Psychiatry. 19: 108-14. PMID 23164818 DOI: 10.1038/Mp.2012.157  0.448
2014 Legge S, Hamshere M, Ripke S, Richards A, Moran J, Chambert K, McCarroll SA, Rujescu D, O'Donovan M, Owen M, Walters JTR. 5:15 Pm Novel Genetic Risk Variants For Clozapine-Associated Neutropenia Schizophrenia Research. 153. DOI: 10.1016/S0920-9964(14)70214-2  0.329
2014 Walters JTR, Pocklington A, Rees E, Ripke S, Moran J, McCarroll SA, Kirov G, O'Donovan M, Owen M. 5:00 Pm Dopamine Or Glutamate: Using Genetic Copy Number Variant Pathway Analysis And Treatment Resistance To Adjudicate Schizophrenia Hypotheses Schizophrenia Research. 153. DOI: 10.1016/S0920-9964(14)70195-1  0.335
2013 Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, DeStafano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thorton-Wells TA, Jones N, Smith AV, Chouraki V, ... ... Owen MJ, et al. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nature Genetics. 45: 1452-8. PMID 24162737 DOI: 10.1038/Ng.2802  0.731
2013 Grozeva D, Kirov G, Conrad DF, Barnes CP, Hurles M, Owen MJ, O'Donovan MC, Craddock N. Reduced burden of very large and rare CNVs in bipolar affective disorder. Bipolar Disorders. 15: 893-8. PMID 24127788 DOI: 10.1111/Bdi.12125  0.416
2013 Schosser A, Butler AW, Uher R, Ng MY, Cohen-Woods S, Craddock N, Owen MJ, Korszun A, Gill M, Rice J, Hauser J, Henigsberg N, Maier W, Mors O, Placentino A, et al. Genome-wide association study of co-occurring anxiety in major depression. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 14: 611-21. PMID 24047446 DOI: 10.3109/15622975.2013.782107  0.347
2013 Ripke S, O'Dushlaine C, Chambert K, Moran JL, Kähler AK, Akterin S, Bergen SE, Collins AL, Crowley JJ, Fromer M, Kim Y, Lee SH, Magnusson PK, Sanchez N, Stahl EA, ... ... Owen MJ, ... ... Owen MJ, et al. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nature Genetics. 45: 1150-9. PMID 23974872 DOI: 10.1038/Ng.2742  0.44
2013 Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, Perlis RH, Mowry BJ, Thapar A, Goddard ME, Witte JS, Absher D, Agartz I, Akil H, Amin F, ... ... Owen MJ, et al. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nature Genetics. 45: 984-94. PMID 23933821 DOI: 10.1038/Ng.2711  0.375
2013 Moskvina V, Harold D, Russo G, Vedernikov A, Sharma M, Saad M, Holmans P, Bras JM, Bettella F, Keller MF, Nicolaou N, Simón-Sánchez J, Gibbs JR, Schulte C, Durr A, ... ... Owen MJ, et al. Analysis of genome-wide association studies of Alzheimer disease and of Parkinson disease to determine if these 2 diseases share a common genetic risk. Jama Neurology. 70: 1268-76. PMID 23921447 DOI: 10.1001/Jamaneurol.2013.448  0.709
2013 Walters JT, Rujescu D, Franke B, Giegling I, Vásquez AA, Hargreaves A, Russo G, Morris DW, Hoogman M, Da Costa A, Moskvina V, Fernández G, Gill M, Corvin A, O'Donovan MC, ... ... Owen MJ, et al. The role of the major histocompatibility complex region in cognition and brain structure: a schizophrenia GWAS follow-up. The American Journal of Psychiatry. 170: 877-85. PMID 23903335 DOI: 10.1176/Appi.Ajp.2013.12020226  0.39
2013 Aberg KA, Liu Y, Bukszár J, McClay JL, Khachane AN, Andreassen OA, Blackwood D, Corvin A, Djurovic S, Gurling H, Ophoff R, Pato CN, Pato MT, Riley B, Webb T, ... ... Owen M, et al. A comprehensive family-based replication study of schizophrenia genes. Jama Psychiatry. 70: 573-81. PMID 23894747 DOI: 10.1001/Jamapsychiatry.2013.288  0.412
2013 Tandon R, Heckers S, Bustillo J, Barch DM, Gaebel W, Gur RE, Malaspina D, Owen MJ, Schultz S, Tsuang M, van Os J, Carpenter W. Catatonia in DSM-5. Schizophrenia Research. 150: 26-30. PMID 23806583 DOI: 10.1016/J.Schres.2013.04.034  0.346
2013 Tandon R, Gaebel W, Barch DM, Bustillo J, Gur RE, Heckers S, Malaspina D, Owen MJ, Schultz S, Tsuang M, Van Os J, Carpenter W. Definition and description of schizophrenia in the DSM-5. Schizophrenia Research. 150: 3-10. PMID 23800613 DOI: 10.1016/J.Schres.2013.05.028  0.352
2013 Tsuang MT, Van Os J, Tandon R, Barch DM, Bustillo J, Gaebel W, Gur RE, Heckers S, Malaspina D, Owen MJ, Schultz S, Carpenter W. Attenuated psychosis syndrome in DSM-5. Schizophrenia Research. 150: 31-5. PMID 23773295 DOI: 10.1016/J.Schres.2013.05.004  0.347
2013 Malaspina D, Owen MJ, Heckers S, Tandon R, Bustillo J, Schultz S, Barch DM, Gaebel W, Gur RE, Tsuang M, Van Os J, Carpenter W. Schizoaffective Disorder in the DSM-5. Schizophrenia Research. 150: 21-5. PMID 23707642 DOI: 10.1016/J.Schres.2013.04.026  0.322
2013 Heckers S, Barch DM, Bustillo J, Gaebel W, Gur R, Malaspina D, Owen MJ, Schultz S, Tandon R, Tsuang M, Van Os J, Carpenter W. Structure of the psychotic disorders classification in DSM-5. Schizophrenia Research. 150: 11-4. PMID 23707641 DOI: 10.1016/J.Schres.2013.04.039  0.348
2013 Barch DM, Bustillo J, Gaebel W, Gur R, Heckers S, Malaspina D, Owen MJ, Schultz S, Tandon R, Tsuang M, Van Os J, Carpenter W. Logic and justification for dimensional assessment of symptoms and related clinical phenomena in psychosis: relevance to DSM-5. Schizophrenia Research. 150: 15-20. PMID 23706415 DOI: 10.1016/J.Schres.2013.04.027  0.307
2013 Hamshere ML, Stergiakouli E, Langley K, Martin J, Holmans P, Kent L, Owen MJ, Gill M, Thapar A, O'Donovan M, Craddock N. Shared polygenic contribution between childhood attention-deficit hyperactivity disorder and adult schizophrenia. The British Journal of Psychiatry : the Journal of Mental Science. 203: 107-11. PMID 23703318 DOI: 10.1192/Bjp.Bp.112.117432  0.389
2013 Hamshere ML, Langley K, Martin J, Agha SS, Stergiakouli E, Anney RJ, Buitelaar J, Faraone SV, Lesch KP, Neale BM, Franke B, Sonuga-Barke E, Asherson P, Merwood A, Kuntsi J, ... ... Owen MJ, et al. High loading of polygenic risk for ADHD in children with comorbid aggression. The American Journal of Psychiatry. 170: 909-16. PMID 23599091 DOI: 10.1176/Appi.Ajp.2013.12081129  0.306
2013 Kavanagh DH, Dwyer S, O'Donovan MC, Owen MJ. The ENCODE project: implications for psychiatric genetics. Molecular Psychiatry. 18: 540-2. PMID 23478746 DOI: 10.1038/Mp.2013.13  0.308
2013 Delio M, Guo T, McDonald-McGinn DM, Zackai E, Herman S, Kaminetzky M, Higgins AM, Coleman K, Chow C, Jalbrzikowski M, Jarlbrzkowski M, Bearden CE, Bailey A, Vangkilde A, Olsen L, ... ... Owen MJ, et al. Enhanced maternal origin of the 22q11.2 deletion in velocardiofacial and DiGeorge syndromes. American Journal of Human Genetics. 92: 439-47. PMID 23453669 DOI: 10.1016/j.ajhg.2013.01.018  0.311
2013 Majounie E, Cross W, Newsway V, Dillman A, Vandrovcova J, Morris CM, Nalls MA, Ferrucci L, Owen MJ, O'Donovan MC, Cookson MR, Singleton AB, de Silva R, Morris HR. Variation in tau isoform expression in different brain regions and disease states. Neurobiology of Aging. 34: 1922.e7-1922.e12. PMID 23428180 DOI: 10.1016/J.Neurobiolaging.2013.01.017  0.622
2013 Chapuis J, Hansmannel F, Gistelinck M, Mounier A, Van Cauwenberghe C, Kolen KV, Geller F, Sottejeau Y, Harold D, Dourlen P, Grenier-Boley B, Kamatani Y, Delepine B, Demiautte F, Zelenika D, ... ... Owen M, et al. Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology. Molecular Psychiatry. 18: 1225-34. PMID 23399914 DOI: 10.1038/Mp.2013.1  0.347
2013 Peall KJ, Smith DJ, Kurian MA, Wardle M, Waite AJ, Hedderly T, Lin JP, Smith M, Whone A, Pall H, White C, Lux A, Jardine P, Bajaj N, Lynch B, ... ... Owen MJ, et al. SGCE mutations cause psychiatric disorders: clinical and genetic characterization. Brain : a Journal of Neurology. 136: 294-303. PMID 23365103 DOI: 10.1093/Brain/Aws308  0.301
2013 Williams HJ, Monks S, Murphy KC, Kirov G, O'Donovan MC, Owen MJ. Schizophrenia two-hit hypothesis in velo-cardio facial syndrome. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 162: 177-82. PMID 23335482 DOI: 10.1002/Ajmg.B.32129  0.421
2013 Guha S, Rees E, Darvasi A, Ivanov D, Ikeda M, Bergen SE, Magnusson PK, Cormican P, Morris D, Gill M, Cichon S, Rosenfeld JA, Lee A, Gregersen PK, Kane JM, ... ... Owen MJ, et al. Implication of a rare deletion at distal 16p11.2 in schizophrenia. Jama Psychiatry. 70: 253-60. PMID 23325106 DOI: 10.1001/2013.Jamapsychiatry.71  0.437
2013 Ruderfer DM, Chambert K, Moran J, Talkowski M, Chen ES, Gigek C, Gusella JF, Blackwood DH, Corvin A, Gurling HM, Hultman CM, Kirov G, Magnusson P, O'Donovan MC, Owen MJ, et al. Mosaic copy number variation in schizophrenia. European Journal of Human Genetics : Ejhg. 21: 1007-11. PMID 23321615 DOI: 10.1038/Ejhg.2012.287  0.386
2013 Donohoe G, Walters J, Hargreaves A, Rose EJ, Morris DW, Fahey C, Bellini S, Cummins E, Giegling I, Hartmann AM, Möller HJ, Muglia P, Owen MJ, Gill M, O'Donovan MC, et al. Neuropsychological effects of the CSMD1 genome-wide associated schizophrenia risk variant rs10503253. Genes, Brain, and Behavior. 12: 203-9. PMID 23320435 DOI: 10.1111/Gbb.12016  0.384
2013 Power RA, Wingenbach T, Cohen-Woods S, Uher R, Ng MY, Butler AW, Ising M, Craddock N, Owen MJ, Korszun A, Jones L, Jones I, Gill M, Rice JP, Maier W, et al. Estimating the heritability of reporting stressful life events captured by common genetic variants. Psychological Medicine. 43: 1965-71. PMID 23237013 DOI: 10.1017/S0033291712002589  0.373
2013 Kim Y, Ripke S, Kirov G, Sklar P, Purcell SM, Owen MJ, O'Donovan MC, Sullivan PF. Non-random mating, parent-of-origin, and maternal-fetal incompatibility effects in schizophrenia. Schizophrenia Research. 143: 11-7. PMID 23177929 DOI: 10.1016/J.Schres.2012.11.002  0.38
2013 Chapman J, Rees E, Harold D, Ivanov D, Gerrish A, Sims R, Hollingworth P, Stretton A, Holmans P, Owen MJ, O'Donovan MC, Williams J, Kirov G. A genome-wide study shows a limited contribution of rare copy number variants to Alzheimer's disease risk. Human Molecular Genetics. 22: 816-24. PMID 23148125 DOI: 10.1093/Hmg/Dds476  0.462
2013 Hamshere ML, Walters JT, Smith R, Richards AL, Green E, Grozeva D, Jones I, Forty L, Jones L, Gordon-Smith K, Riley B, O'Neill FA, O'Neill T, Kendler KS, Sklar P, ... ... Owen MJ, et al. Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC. Molecular Psychiatry. 18: 708-12. PMID 22614287 DOI: 10.1038/Mp.2012.67  0.319
2013 Lambert JC, Grenier-Boley B, Harold D, Zelenika D, Chouraki V, Kamatani Y, Sleegers K, Ikram MA, Hiltunen M, Reitz C, Mateo I, Feulner T, Bullido M, Galimberti D, Concari L, ... ... Owen M, et al. Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease. Molecular Psychiatry. 18: 461-70. PMID 22430674 DOI: 10.1038/Mp.2012.14  0.421
2013 Rucker JJ, Breen G, Pinto D, Pedroso I, Lewis CM, Cohen-Woods S, Uher R, Schosser A, Rivera M, Aitchison KJ, Craddock N, Owen MJ, Jones L, Jones I, Korszun A, et al. Genome-wide association analysis of copy number variation in recurrent depressive disorder. Molecular Psychiatry. 18: 183-9. PMID 22042228 DOI: 10.1038/Mp.2011.144  0.364
2013 Peall K, Smith D, Kurian M, Wardle M, Waite A, Hedderly T, Lin J, Smith M, Whone A, Pall H, White C, Lux A, Jardine P, Bajaj N, Lynch B, ... ... Owen MJ, et al. Are Psychiatric Symptoms A Core Phenotype Of Myoclonus Dystonia Syndrome Caused By Sgce Mutations Journal of Neurology, Neurosurgery, and Psychiatry. 84. DOI: 10.1136/Jnnp-2013-306103.24  0.331
2013 Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, ... ... Owen MJ, et al. Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease Nature Genetics. 45: 712-712. DOI: 10.1038/Ng0613-712A  0.785
2012 Fromer M, Moran JL, Chambert K, Banks E, Bergen SE, Ruderfer DM, Handsaker RE, McCarroll SA, O'Donovan MC, Owen MJ, Kirov G, Sullivan PF, Hultman CM, Sklar P, Purcell SM. Discovery and statistical genotyping of copy-number variation from whole-exome sequencing depth. American Journal of Human Genetics. 91: 597-607. PMID 23040492 DOI: 10.1016/J.Ajhg.2012.08.005  0.365
2012 Owen MJ. Implications of genetic findings for understanding schizophrenia. Schizophrenia Bulletin. 38: 904-7. PMID 22987847 DOI: 10.1093/Schbul/Sbs103  0.386
2012 Williams HJ, Georgieva L, Dwyer S, Kirov G, Owen MJ, O'Donovan MC. Absence of de novo point mutations in exons of GRIN2B in a large schizophrenia trio sample. Schizophrenia Research. 141: 274-6. PMID 22986046 DOI: 10.1016/J.Schres.2012.08.024  0.311
2012 Power RA, Keers R, Ng MY, Butler AW, Uher R, Cohen-Woods S, Ising M, Craddock N, Owen MJ, Korszun A, Jones L, Jones I, Gill M, Rice JP, Hauser J, et al. Dissecting the genetic heterogeneity of depression through age at onset. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 159: 859-68. PMID 22915352 DOI: 10.1002/Ajmg.B.32093  0.381
2012 Levinson DF, Shi J, Wang K, Oh S, Riley B, Pulver AE, Wildenauer DB, Laurent C, Mowry BJ, Gejman PV, Owen MJ, Kendler KS, Nestadt G, Schwab SG, Mallet J, et al. Genome-wide association study of multiplex schizophrenia pedigrees. The American Journal of Psychiatry. 169: 963-73. PMID 22885689 DOI: 10.1176/Appi.Ajp.2012.11091423  0.446
2012 O'Donovan MC, Owen MJ, Walters JTR. Genome-Wide Association study implicates HLA-C*01:02 as a risk factor at the major histocompatibility complex locus in schizophrenia Biological Psychiatry. 72: 620-628. PMID 22883433 DOI: 10.1016/J.Biopsych.2012.05.035  0.424
2012 Fowler T, Zammit S, Owen MJ, Rasmussen F. A population-based study of shared genetic variation between premorbid IQ and psychosis among male twin pairs and sibling pairs from Sweden. Archives of General Psychiatry. 69: 460-6. PMID 22566578 DOI: 10.1001/Archgenpsychiatry.2011.1370  0.363
2012 HÃ¥vik B, Degenhardt FA, Johansson S, Fernandes CP, Hinney A, Scherag A, Lybæk H, Djurovic S, Christoforou A, Ersland KM, Giddaluru S, O'Donovan MC, Owen MJ, Craddock N, Mühleisen TW, et al. DCLK1 variants are associated across schizophrenia and attention deficit/hyperactivity disorder. Plos One. 7: e35424. PMID 22539971 DOI: 10.1371/Journal.Pone.0035424  0.376
2012 Owen MJ. Intellectual disability and major psychiatric disorders: a continuum of neurodevelopmental causality. The British Journal of Psychiatry : the Journal of Mental Science. 200: 268-9. PMID 22474230 DOI: 10.1192/Bjp.Bp.111.105551  0.367
2012 Rees E, Kirov G, O'Donovan MC, Owen MJ. De novo mutation in schizophrenia. Schizophrenia Bulletin. 38: 377-81. PMID 22451492 DOI: 10.1093/Schbul/Sbs047  0.347
2012 Williams NM, Franke B, Mick E, Anney RJ, Freitag CM, Gill M, Thapar A, O'Donovan MC, Owen MJ, Holmans P, Kent L, Middleton F, Zhang-James Y, Liu L, Meyer J, et al. Genome-wide analysis of copy number variants in attention deficit hyperactivity disorder: the role of rare variants and duplications at 15q13.3. The American Journal of Psychiatry. 169: 195-204. PMID 22420048 DOI: 10.1176/Appi.Ajp.2011.11060822  0.362
2012 Stergiakouli E, Hamshere M, Holmans P, Langley K, Zaharieva I, Hawi Z, Kent L, Gill M, Williams N, Owen MJ, O'Donovan M, Thapar A. Investigating the contribution of common genetic variants to the risk and pathogenesis of ADHD. The American Journal of Psychiatry. 169: 186-94. PMID 22420046 DOI: 10.1176/Appi.Ajp.2011.11040551  0.399
2012 Moskvina V, Schmidt KM, Vedernikov A, Owen MJ, Craddock N, Holmans P, O'Donovan MC. Permutation-based approaches do not adequately allow for linkage disequilibrium in gene-wide multi-locus association analysis. European Journal of Human Genetics : Ejhg. 20: 890-6. PMID 22317971 DOI: 10.1038/Ejhg.2012.8  0.335
2012 Grozeva D, Conrad DF, Barnes CP, Hurles M, Owen MJ, O'Donovan MC, Craddock N, Kirov G. Independent estimation of the frequency of rare CNVs in the UK population confirms their role in schizophrenia. Schizophrenia Research. 135: 1-7. PMID 22130109 DOI: 10.1016/J.Schres.2011.11.004  0.424
2012 Kirov G, Pocklington AJ, Holmans P, Ivanov D, Ikeda M, Ruderfer D, Moran J, Chambert K, Toncheva D, Georgieva L, Grozeva D, Fjodorova M, Wollerton R, Rees E, Nikolov I, ... ... Owen MJ, et al. De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia. Molecular Psychiatry. 17: 142-53. PMID 22083728 DOI: 10.1038/Mp.2011.154  0.406
2012 Gerrish A, Russo G, Richards A, Moskvina V, Ivanov D, Harold D, Sims R, Abraham R, Hollingworth P, Chapman J, Hamshere M, Pahwa JS, Dowzell K, Williams A, Jones N, ... ... Owen MJ, et al. The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 28: 377-87. PMID 22027014 DOI: 10.3233/Jad-2011-110824  0.816
2012 Hollingworth P, Sweet R, Sims R, Harold D, Russo G, Abraham R, Stretton A, Jones N, Gerrish A, Chapman J, Ivanov D, Moskvina V, Lovestone S, Priotsi P, Lupton M, ... ... Owen MJ, et al. Genome-wide association study of Alzheimer's disease with psychotic symptoms. Molecular Psychiatry. 17: 1316-27. PMID 22005930 DOI: 10.1016/J.Jalz.2011.05.516  0.385
2012 Doherty JL, O'Donovan MC, Owen MJ. Recent genomic advances in schizophrenia. Clinical Genetics. 81: 103-9. PMID 21895634 DOI: 10.1111/J.1399-0004.2011.01773.X  0.439
2012 Rietschel M, Mattheisen M, Degenhardt F, Mühleisen TW, Kirsch P, Esslinger C, Herms S, Demontis D, Steffens M, Strohmaier J, Haenisch B, Breuer R, Czerski PM, Giegling I, ... ... Owen MJ, et al. Association between genetic variation in a region on chromosome 11 and schizophrenia in large samples from Europe. Molecular Psychiatry. 17: 906-17. PMID 21747397 DOI: 10.1038/Mp.2011.80  0.43
2012 Rivera M, Cohen-Woods S, Kapur K, Breen G, Ng MY, Butler AW, Craddock N, Gill M, Korszun A, Maier W, Mors O, Owen MJ, Preisig M, Bergmann S, Tozzi F, et al. Depressive disorder moderates the effect of the FTO gene on body mass index. Molecular Psychiatry. 17: 604-11. PMID 21502950 DOI: 10.1038/Mp.2011.45  0.338
2012 Richards AL, Jones L, Moskvina V, Kirov G, Gejman PV, Levinson DF, Sanders AR, Purcell S, Visscher PM, Craddock N, Owen MJ, Holmans P, O'Donovan MC. Schizophrenia susceptibility alleles are enriched for alleles that affect gene expression in adult human brain. Molecular Psychiatry. 17: 193-201. PMID 21339752 DOI: 10.1038/Mp.2011.11  0.437
2012 Proitsi P, Lupton MK, Reeves SJ, Hamilton G, Archer N, Martin BM, Iyegbe C, Hollingworth P, Lawlor B, Gill M, Brayne C, Rubinsztein DC, Owen MJ, Williams J, Lovestone S, et al. Association of serotonin and dopamine gene pathways with behavioral subphenotypes in dementia. Neurobiology of Aging. 33: 791-803. PMID 20685009 DOI: 10.1016/J.Neurobiolaging.2010.06.011  0.342
2012 Owen M. The Origins of Schizophrenia British Journal of Psychiatry. 201: 162-162. DOI: 10.1192/Bjp.Bp.111.107300  0.321
2012 Peall K, Waite AJ, Kurian MA, Hedderly T, Smith M, Lin JP, Warner TT, Pall H, Chinnery P, Whone A, Owen MJ, Blake DJ, Morris HR. 1624 Myoclonus dystonia: a clinical and genetic description Journal of Neurology, Neurosurgery, and Psychiatry. 83. DOI: 10.1136/Jnnp-2011-301993.29  0.304
2012 Desikan R, McEvoy L, Schork A, Thompson W, Brewer J, Van De Bunt M, Morris A, McCarthy M, Owen M, O'Donovan M, Williams J, Hyman B, Andreassen O, Dale A. O1-09-05: On genetic pleiotropy between Alzheimer's disease and cardiovascular risk factors Alzheimer's & Dementia. 8: P101-P102. DOI: 10.1016/J.Jalz.2012.05.255  0.313
2011 Langley K, Martin J, Agha SS, Davies C, Stergiakouli E, Holmans P, Williams N, Owen M, O'Donovan M, Thapar A. Clinical and cognitive characteristics of children with attention-deficit hyperactivity disorder, with and without copy number variants. The British Journal of Psychiatry : the Journal of Mental Science. 199: 398-403. PMID 22045946 DOI: 10.1192/Bjp.Bp.111.092130  0.324
2011 Hamshere ML, O'Donovan MC, Jones IR, Jones L, Kirov G, Green EK, Moskvina V, Grozeva D, Bass N, McQuillin A, Gurling H, St Clair D, Young AH, Ferrier IN, Farmer A, ... ... Owen MJ, et al. Polygenic dissection of the bipolar phenotype. The British Journal of Psychiatry : the Journal of Mental Science. 198: 284-8. PMID 21972277 DOI: 10.1192/Bjp.Bp.110.087866  0.387
2011 Hamshere ML, Holmans PA, McCarthy GM, Jones LA, Murphy KC, Sanders RD, Gray MY, Zammit S, Williams NM, Norton N, Williams HJ, McGuffin P, O'Donovan MC, Craddock N, Owen MJ, et al. Phenotype evaluation and genomewide linkage study of clinical variables in schizophrenia. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 156: 929-40. PMID 21960518 DOI: 10.1002/Ajmg.B.31240  0.399
2011 Zammit S, Owen MJ, Evans J, Heron J, Lewis G. Cannabis, COMT and psychotic experiences. The British Journal of Psychiatry : the Journal of Mental Science. 199: 380-5. PMID 21947654 DOI: 10.1192/Bjp.Bp.111.091421  0.356
2011 Rees E, Moskvina V, Owen MJ, O'Donovan MC, Kirov G. De novo rates and selection of schizophrenia-associated copy number variants. Biological Psychiatry. 70: 1109-14. PMID 21855053 DOI: 10.1016/J.Biopsych.2011.07.011  0.346
2011 Carroll LS, Williams HJ, Walters J, Kirov G, O'Donovan MC, Owen MJ. Mutation screening of the 3q29 microdeletion syndrome candidate genes DLG1 and PAK2 in schizophrenia. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 156: 844-9. PMID 21850710 DOI: 10.1002/Ajmg.B.31231  0.382
2011 Williams HJ, Moskvina V, Smith RL, Dwyer S, Russo G, Owen MJ, O'Donovan MC. Association between TCF4 and schizophrenia does not exert its effect by common nonsynonymous variation or by influencing cis-acting regulation of mRNA expression in adult human brain. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 156: 781-4. PMID 21812098 DOI: 10.1002/Ajmg.B.31219  0.402
2011 Sims R, Dwyer S, Harold D, Gerrish A, Hollingworth P, Chapman J, Jones N, Abraham R, Ivanov D, Pahwa JS, Moskvina V, Dowzell K, Thomas C, Stretton A, Lovestone S, ... ... Owen MJ, et al. No evidence that extended tracts of homozygosity are associated with Alzheimer's disease. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 156: 764-71. PMID 21812096 DOI: 10.1002/Ajmg.B.31216  0.638
2011 Steinberg S, de Jong S, Andreassen OA, Werge T, Børglum AD, Mors O, Mortensen PB, Gustafsson O, Costas J, Pietiläinen OP, Demontis D, Papiol S, Huttenlocher J, Mattheisen M, ... ... Owen MJ, et al. Common variants at VRK2 and TCF4 conferring risk of schizophrenia. Human Molecular Genetics. 20: 4076-81. PMID 21791550 DOI: 10.1093/Hmg/Ddr325  0.434
2011 Yosifova A, Mushiroda T, Kubo M, Takahashi A, Kamatani Y, Kamatani N, Stoianov D, Vazharova R, Karachanak S, Zaharieva I, Dimova I, Hadjidekova S, Milanova V, Madjirova N, Gerdjikov I, ... ... Owen MJ, et al. Genome-wide association study on bipolar disorder in the Bulgarian population. Genes, Brain, and Behavior. 10: 789-97. PMID 21771265 DOI: 10.1111/J.1601-183X.2011.00721.X  0.394
2011 Schosser A, Butler AW, Ising M, Perroud N, Uher R, Ng MY, Cohen-Woods S, Craddock N, Owen MJ, Korszun A, Jones L, Jones I, Gill M, Rice JP, Maier W, et al. Genomewide association scan of suicidal thoughts and behaviour in major depression. Plos One. 6: e20690. PMID 21750702 DOI: 10.1371/Journal.Pone.0020690  0.32
2011 Peall KJ, Waite AJ, Blake DJ, Owen MJ, Morris HR. Psychiatric disorders, myoclonus dystonia, and the epsilon-sarcoglycan gene: a systematic review. Movement Disorders : Official Journal of the Movement Disorder Society. 26: 1939-42. PMID 21713999 DOI: 10.1002/Mds.23791  0.325
2011 Samaan Z, Gaysina D, Cohen-Woods S, Craddock N, Jones L, Korszun A, Owen M, Mente A, McGuffin P, Farmer A. Methylenetetrahydrofolate reductase gene variant (MTHFR C677T) and migraine: a case control study and meta-analysis. Bmc Neurology. 11: 66. PMID 21635773 DOI: 10.1186/1471-2377-11-66  0.327
2011 Breen G, Webb BT, Butler AW, van den Oord EJ, Tozzi F, Craddock N, Gill M, Korszun A, Maier W, Middleton L, Mors O, Owen MJ, Cohen-Woods S, Perry J, Galwey NW, et al. A genome-wide significant linkage for severe depression on chromosome 3: the depression network study. The American Journal of Psychiatry. 168: 840-7. PMID 21572164 DOI: 10.1176/Appi.Ajp.2011.10091342  0.319
2011 Smith RL, Knight D, Williams H, Dwyer S, Richards A, Kirov G, O'Donovan MC, Owen MJ. Analysis of neurogranin (NRGN) in schizophrenia. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 156: 532-5. PMID 21538840 DOI: 10.1002/Ajmg.B.31191  0.411
2011 Ruderfer DM, Kirov G, Chambert K, Moran JL, Owen MJ, O'Donovan MC, Sklar P, Purcell SM. A family-based study of common polygenic variation and risk of schizophrenia. Molecular Psychiatry. 16: 887-8. PMID 21483432 DOI: 10.1038/Mp.2011.34  0.424
2011 Moskvina V, Craddock N, Müller-Myhsok B, Kam-Thong T, Green E, Holmans P, Owen MJ, O'Donovan MC. An examination of single nucleotide polymorphism selection prioritization strategies for tests of gene-gene interaction. Biological Psychiatry. 70: 198-203. PMID 21481336 DOI: 10.1016/J.Biopsych.2011.01.034  0.388
2011 Hollingworth P, Harold D, Sims R, Gerrish A, Lambert JC, Carrasquillo MM, Abraham R, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Jones N, Stretton A, Thomas C, Richards A, ... ... Owen MJ, et al. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nature Genetics. 43: 429-35. PMID 21460840 DOI: 10.1038/Ng.803  0.773
2011 Hansen T, Ingason A, Djurovic S, Melle I, Fenger M, Gustafsson O, Jakobsen KD, Rasmussen HB, Tosato S, Rietschel M, Frank J, Owen M, Bonetto C, Suvisaari J, Thygesen JH, et al. At-risk variant in TCF7L2 for type II diabetes increases risk of schizophrenia. Biological Psychiatry. 70: 59-63. PMID 21414605 DOI: 10.1016/J.Biopsych.2011.01.031  0.374
2011 Owen MJ. Is there a schizophrenia to diagnose? World Psychiatry : Official Journal of the World Psychiatric Association (Wpa). 10: 34-5. PMID 21379350 DOI: 10.1002/J.2051-5545.2011.Tb00007.X  0.399
2011 Owen MJ, O'Donovan MC, Thapar A, Craddock N. Neurodevelopmental hypothesis of schizophrenia. The British Journal of Psychiatry : the Journal of Mental Science. 198: 173-5. PMID 21357874 DOI: 10.1192/Bjp.Bp.110.084384  0.377
2011 Cichon S, Mühleisen TW, Degenhardt FA, Mattheisen M, Miró X, Strohmaier J, Steffens M, Meesters C, Herms S, Weingarten M, Priebe L, Haenisch B, Alexander M, Vollmer J, Breuer R, ... ... Owen MJ, et al. Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder. American Journal of Human Genetics. 88: 372-81. PMID 21353194 DOI: 10.1016/J.Ajhg.2011.01.017  0.413
2011 Ingason A, Kirov G, Giegling I, Hansen T, Isles AR, Jakobsen KD, Kristinsson KT, le Roux L, Gustafsson O, Craddock N, Möller HJ, McQuillin A, Muglia P, Cichon S, Rietschel M, ... ... Owen MJ, et al. Maternally derived microduplications at 15q11-q13: implication of imprinted genes in psychotic illness. The American Journal of Psychiatry. 168: 408-17. PMID 21324950 DOI: 10.1176/Appi.Ajp.2010.09111660  0.365
2011 Belbin O, Brown K, Shi H, Medway C, Abraham R, Passmore P, Mann D, Smith AD, Holmes C, McGuinness B, Craig D, Warden D, Heun R, Kölsch H, Love S, ... ... Owen MJ, et al. A multi-center study of ACE and the risk of late-onset Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 24: 587-97. PMID 21297258 DOI: 10.3233/Jad-2011-101914  0.368
2011 Dwyer S, Williams H, Jones I, Jones L, Walters J, Craddock N, Owen MJ, O'Donovan MC. Investigation of rare non-synonymous variants at ABCA13 in schizophrenia and bipolar disorder. Molecular Psychiatry. 16: 790-1. PMID 21283083 DOI: 10.1038/Mp.2011.2  0.377
2011 Stergiakouli E, Langley K, Williams H, Walters J, Williams NM, Suren S, Giegling I, Wilkinson LS, Owen MJ, O'Donovan MC, Rujescu D, Thapar A, Davies W. Steroid sulfatase is a potential modifier of cognition in attention deficit hyperactivity disorder. Genes, Brain, and Behavior. 10: 334-44. PMID 21255266 DOI: 10.1111/J.1601-183X.2010.00672.X  0.316
2011 Zuliani R, Moorhead TW, Bastin ME, Johnstone EC, Lawrie SM, Brambilla P, O'Donovan MC, Owen MJ, Hall J, McIntosh AM. Genetic variants in the ErbB4 gene are associated with white matter integrity. Psychiatry Research. 191: 133-7. PMID 21232925 DOI: 10.1016/J.Pscychresns.2010.11.001  0.427
2011 Reitz C, Cheng R, Rogaeva E, Lee JH, Tokuhiro S, Zou F, Bettens K, Sleegers K, Tan EK, Kimura R, Shibata N, Arai H, Kamboh MI, Prince JA, Maier W, ... ... Owen M, et al. Meta-analysis of the association between variants in SORL1 and Alzheimer disease. Archives of Neurology. 68: 99-106. PMID 21220680 DOI: 10.1001/Archneurol.2010.346  0.397
2011 Donohoe G, Walters J, Morris DW, Da Costa A, Rose E, Hargreaves A, Maher K, Hayes E, Giegling I, Hartmann AM, Möller HJ, Muglia P, Moskvina V, Owen MJ, O'Donovan MC, et al. A neuropsychological investigation of the genome wide associated schizophrenia risk variant NRGN rs12807809. Schizophrenia Research. 125: 304-6. PMID 21112188 DOI: 10.1016/J.Schres.2010.10.019  0.389
2011 Williams HJ, Craddock N, Russo G, Hamshere ML, Moskvina V, Dwyer S, Smith RL, Green E, Grozeva D, Holmans P, Owen MJ, O'Donovan MC. Most genome-wide significant susceptibility loci for schizophrenia and bipolar disorder reported to date cross-traditional diagnostic boundaries. Human Molecular Genetics. 20: 387-91. PMID 21037240 DOI: 10.1093/Hmg/Ddq471  0.446
2011 Hollingworth P, Harold D, Jones L, Owen MJ, Williams J. Alzheimer's disease genetics: current knowledge and future challenges. International Journal of Geriatric Psychiatry. 26: 793-802. PMID 20957767 DOI: 10.1002/Gps.2628  0.412
2011 Chen X, Lee G, Maher BS, Fanous AH, Chen J, Zhao Z, Guo A, van den Oord E, Sullivan PF, Shi J, Levinson DF, Gejman PV, Sanders A, Duan J, Owen MJ, et al. GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia. Molecular Psychiatry. 16: 1117-29. PMID 20838396 DOI: 10.1038/Mp.2010.96  0.421
2011 Ikeda M, Aleksic B, Kinoshita Y, Okochi T, Kawashima K, Kushima I, Ito Y, Nakamura Y, Kishi T, Okumura T, Fukuo Y, Williams HJ, Hamshere ML, Ivanov D, Inada T, ... ... Owen MJ, et al. Genome-wide association study of schizophrenia in a Japanese population. Biological Psychiatry. 69: 472-8. PMID 20832056 DOI: 10.1016/J.Biopsych.2010.07.010  0.429
2011 Williams HJ, Norton N, Dwyer S, Moskvina V, Nikolov I, Carroll L, Georgieva L, Williams NM, Morris DW, Quinn EM, Giegling I, Ikeda M, Wood J, Lencz T, Hultman C, ... ... Owen MJ, et al. Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder. Molecular Psychiatry. 16: 429-41. PMID 20368704 DOI: 10.1038/Mp.2010.36  0.443
2011 Liu Y, Blackwood DH, Caesar S, de Geus EJ, Farmer A, Ferreira MA, Ferrier IN, Fraser C, Gordon-Smith K, Green EK, Grozeva D, Gurling HM, Hamshere ML, Heutink P, Holmans PA, ... ... Owen MJ, et al. Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder. Molecular Psychiatry. 16: 2-4. PMID 20351715 DOI: 10.1038/Mp.2009.107  0.322
2011 Proitsi P, Hamilton G, Tsolaki M, Lupton M, Daniilidou M, Hollingworth P, Archer N, Foy C, Stylios F, McGuinness B, Todd S, Lawlor B, Gill M, Brayne C, Rubinsztein DC, ... Owen M, et al. A Multiple Indicators Multiple Causes (MIMIC) model of Behavioural and Psychological Symptoms in Dementia (BPSD). Neurobiology of Aging. 32: 434-42. PMID 19386383 DOI: 10.1016/J.Neurobiolaging.2009.03.005  0.304
2011 Cardno A, Hamshere M, Holmans P, McCarthy G, Jones L, Murphy K, Sanders R, Gray M, Williams N, Norton N, Williams H, McGuffin P, O’Donovan M, Owen M. Genomewide linkage study of clinical variables in schizophrenia International Clinical Psychopharmacology. 26: e107. DOI: 10.1097/01.Yic.0000405814.17185.B1  0.321
2011 Cichon S, Mühleisen TW, Degenhardt FA, Mattheisen M, Miró X, Strohmaier J, Steffens M, Meesters C, Herms S, Weingarten M, Priebe L, Haenisch B, Alexander M, Vollmer J, Breuer R, ... ... Owen MJ, et al. Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder (The American Journal of Human Genetics (2011) 88, (372-381)) American Journal of Human Genetics. 88: 396. DOI: 10.1016/J.Ajhg.2011.03.001  0.346
2010 Langley K, Heron J, O'Donovan MC, Owen MJ, Thapar A. Genotype link with extreme antisocial behavior: the contribution of cognitive pathways. Archives of General Psychiatry. 67: 1317-23. PMID 21135332 DOI: 10.1001/Archgenpsychiatry.2010.163  0.335
2010 Jones L, Holmans PA, Hamshere ML, Harold D, Moskvina V, Ivanov D, Pocklington A, Abraham R, Hollingworth P, Sims R, Gerrish A, Pahwa JS, Jones N, Stretton A, Morgan AR, ... ... Owen MJ, et al. Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease. Plos One. 5: e13950. PMID 21085570 DOI: 10.1371/Journal.Pone.0013950  0.777
2010 Talkowski ME, McCann KL, Chen M, McClain L, Bamne M, Wood J, Chowdari KV, Watson A, Prasad KM, Kirov G, Georgieva L, Toncheva D, Mansour H, Lewis DA, Owen M, et al. Fine-mapping reveals novel alternative splicing of the dopamine transporter. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 153: 1434-47. PMID 20957647 DOI: 10.1002/Ajmg.B.31125  0.416
2010 Williams NM, Zaharieva I, Martin A, Langley K, Mantripragada K, Fossdal R, Stefansson H, Stefansson K, Magnusson P, Gudmundsson OO, Gustafsson O, Holmans P, Owen MJ, O'Donovan M, Thapar A. Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: a genome-wide analysis. Lancet. 376: 1401-8. PMID 20888040 DOI: 10.1016/S0140-6736(10)61109-9  0.372
2010 Butler AW, Breen G, Tozzi F, Craddock N, Gill M, Korszun A, Maier W, Middleton LT, Mors O, Owen MJ, Perry J, Preisig M, Rice JP, Rietschel M, Jones L, et al. A genomewide linkage study on suicidality in major depressive disorder confirms evidence for linkage to 2p12. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 153: 1465-73. PMID 20886545 DOI: 10.1002/Ajmg.B.31127  0.352
2010 Dwyer S, Williams H, Holmans P, Moskvina V, Craddock N, Owen MJ, O'Donovan MC. No evidence that rare coding variants in ZNF804A confer risk of schizophrenia. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 153: 1411-6. PMID 20862696 DOI: 10.1002/ajmg.b.31117  0.325
2010 Neale BM, Medland SE, Ripke S, Asherson P, Franke B, Lesch KP, Faraone SV, Nguyen TT, Schäfer H, Holmans P, Daly M, Steinhausen HC, Freitag C, Reif A, Renner TJ, ... ... Owen M, et al. Meta-analysis of genome-wide association studies of attention-deficit/hyperactivity disorder. Journal of the American Academy of Child and Adolescent Psychiatry. 49: 884-97. PMID 20732625 DOI: 10.1016/J.Jaac.2010.06.008  0.373
2010 Walters JT, Corvin A, Owen MJ, Williams H, Dragovic M, Quinn EM, Judge R, Smith DJ, Norton N, Giegling I, Hartmann AM, Möller HJ, Muglia P, Moskvina V, Dwyer S, et al. Psychosis susceptibility gene ZNF804A and cognitive performance in schizophrenia. Archives of General Psychiatry. 67: 692-700. PMID 20603450 DOI: 10.1001/Archgenpsychiatry.2010.81  0.372
2010 Owen MJ, Craddock N, O'Donovan MC. Suggestion of roles for both common and rare risk variants in genome-wide studies of schizophrenia. Archives of General Psychiatry. 67: 667-73. PMID 20603448 DOI: 10.1001/Archgenpsychiatry.2010.69  0.438
2010 Craddock N, Owen MJ. Molecular genetics and the relationship between epilepsy and psychosis. The British Journal of Psychiatry : the Journal of Mental Science. 197: 75-6; author reply 7. PMID 20592440 DOI: 10.1192/Bjp.197.1.75A  0.36
2010 Green EK, Grozeva D, Moskvina V, Hamshere ML, Jones IR, Jones L, Forty L, Caesar S, Gordon-Smith K, Fraser C, Russell E, St Clair D, Young AH, Ferrier N, Farmer A, ... ... Owen MJ, et al. Variation at the GABAA receptor gene, Rho 1 (GABRR1) associated with susceptibility to bipolar schizoaffective disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 153: 1347-9. PMID 20583128 DOI: 10.1002/Ajmg.B.31108  0.394
2010 Cohen-Woods S, Craig I, Gaysina D, Gray J, Gunasinghe C, Craddock N, Elkin A, Jones L, Kennedy J, King N, Korszun A, Knight J, Owen M, Parikh S, Strauss J, et al. The Bipolar Association Case-Control Study (BACCS) and meta-analysis: No association with the 5,10-Methylenetetrahydrofolate reductase gene and bipolar disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 153: 1298-304. PMID 20552676 DOI: 10.1002/Ajmg.B.31101  0.414
2010 Lewis CM, Ng MY, Butler AW, Cohen-Woods S, Uher R, Pirlo K, Weale ME, Schosser A, Paredes UM, Rivera M, Craddock N, Owen MJ, Jones L, Jones I, Korszun A, et al. Genome-wide association study of major recurrent depression in the U.K. population. The American Journal of Psychiatry. 167: 949-57. PMID 20516156 DOI: 10.1176/Appi.Ajp.2010.09091380  0.318
2010 Seshadri S, Fitzpatrick AL, Ikram MA, DeStefano AL, Gudnason V, Boada M, Bis JC, Smith AV, Carassquillo MM, Lambert JC, Harold D, Schrijvers EM, Ramirez-Lorca R, Debette S, Longstreth WT, ... ... Owen MJ, et al. Genome-wide analysis of genetic loci associated with Alzheimer disease. Jama. 303: 1832-40. PMID 20460622 DOI: 10.1001/Jama.2010.574  0.407
2010 Blake DJ, Forrest M, Chapman RM, Tinsley CL, O'Donovan MC, Owen MJ. TCF4, schizophrenia, and Pitt-Hopkins Syndrome. Schizophrenia Bulletin. 36: 443-7. PMID 20421335 DOI: 10.1093/Schbul/Sbq035  0.432
2010 Grozeva D, Kirov G, Ivanov D, Jones IR, Jones L, Green EK, St Clair DM, Young AH, Ferrier N, Farmer AE, McGuffin P, Holmans PA, Owen MJ, O'Donovan MC, Craddock N, et al. Rare copy number variants: a point of rarity in genetic risk for bipolar disorder and schizophrenia. Archives of General Psychiatry. 67: 318-27. PMID 20368508 DOI: 10.1001/Archgenpsychiatry.2010.25  0.414
2010 Craddock N, Hurles ME, Cardin N, Pearson RD, Plagnol V, Robson S, Vukcevic D, Barnes C, Conrad DF, Giannoulatou E, Holmes C, Marchini JL, Stirrups K, Tobin MD, ... ... Owen MJ, et al. Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature. 464: 713-20. PMID 20360734 DOI: 10.1038/Nature08979  0.404
2010 Craddock N, Owen MJ. The Kraepelinian dichotomy - going, going... but still not gone. The British Journal of Psychiatry : the Journal of Mental Science. 196: 92-5. PMID 20118450 DOI: 10.1192/Bjp.Bp.109.073429  0.348
2010 Ingason A, Giegling I, Cichon S, Hansen T, Rasmussen HB, Nielsen J, Jürgens G, Muglia P, Hartmann AM, Strengman E, Vasilescu C, Mühleisen TW, Djurovic S, Melle I, Lerer B, ... ... Owen MJ, et al. A large replication study and meta-analysis in European samples provides further support for association of AHI1 markers with schizophrenia. Human Molecular Genetics. 19: 1379-86. PMID 20071346 DOI: 10.1093/Hmg/Ddq009  0.437
2010 Kauwe JS, Bertelsen S, Mayo K, Cruchaga C, Abraham R, Hollingworth P, Harold D, Owen MJ, Williams J, Lovestone S, Morris JC, Goate AM. Suggestive synergy between genetic variants in TF and HFE as risk factors for Alzheimer's disease. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 153: 955-9. PMID 20029940 DOI: 10.1002/Ajmg.B.31053  0.575
2010 Ikeda M, Aleksic B, Kirov G, Kinoshita Y, Yamanouchi Y, Kitajima T, Kawashima K, Okochi T, Kishi T, Zaharieva I, Owen MJ, O'Donovan MC, Ozaki N, Iwata N. Copy number variation in schizophrenia in the Japanese population. Biological Psychiatry. 67: 283-6. PMID 19880096 DOI: 10.1016/J.Biopsych.2009.08.034  0.358
2010 Dwyer S, Carroll L, Mantripragada KK, Owen MJ, O'Donovan MC, Williams NM. Mutation screening of the DTNBP1 exonic sequence in 669 schizophrenics and 710 controls using high-resolution melting analysis. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 153: 766-74. PMID 19859905 DOI: 10.1002/Ajmg.B.31045  0.421
2010 Ikeda M, Tomita Y, Mouri A, Koga M, Okochi T, Yoshimura R, Yamanouchi Y, Kinoshita Y, Hashimoto R, Williams HJ, Takeda M, Nakamura J, Nabeshima T, Owen MJ, O'Donovan MC, et al. Identification of novel candidate genes for treatment response to risperidone and susceptibility for schizophrenia: integrated analysis among pharmacogenomics, mouse expression, and genetic case-control association approaches. Biological Psychiatry. 67: 263-9. PMID 19850283 DOI: 10.1016/J.Biopsych.2009.08.030  0.42
2010 Carroll LS, Williams NM, Moskvina V, Russell E, Norton N, Williams HJ, Peirce T, Georgieva L, Dwyer S, Grozeva D, Greene E, Farmer A, McGuffin P, Morris DW, Corvin A, ... ... Owen MJ, et al. Evidence for rare and common genetic risk variants for schizophrenia at protein kinase C, alpha. Molecular Psychiatry. 15: 1101-11. PMID 19786960 DOI: 10.1038/Mp.2009.96  0.315
2010 Green EK, Grozeva D, Jones I, Jones L, Kirov G, Caesar S, Gordon-Smith K, Fraser C, Forty L, Russell E, Hamshere ML, Moskvina V, Nikolov I, Farmer A, McGuffin P, ... ... Owen MJ, et al. The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia. Molecular Psychiatry. 15: 1016-22. PMID 19621016 DOI: 10.1038/Mp.2009.49  0.429
2010 Schosser A, Cohen-Woods S, Gaysina D, Chow PC, Martucci L, Farmer A, Korszun A, Gunashinghe C, Gray J, Jones L, Craddock N, Owen MJ, Craig IW, McGuffin P. NRG1 gene in recurrent major depression: no association in a large-scale case-control association study. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 153: 141-7. PMID 19367584 DOI: 10.1002/Ajmg.B.30965  0.429
2010 Craddock N, Jones L, Jones IR, Kirov G, Green EK, Grozeva D, Moskvina V, Nikolov I, Hamshere ML, Vukcevic D, Caesar S, Gordon-Smith K, Fraser C, Russell E, Norton N, ... ... Owen MJ, et al. Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype. Molecular Psychiatry. 15: 146-53. PMID 19078961 DOI: 10.1038/Mp.2008.66  0.4
2010 Craddock NJ, Owen MJ. Molecular Genetics and the Kraepelinian Dichotomy: One Disorder, Two Disorders, or Do We Need to Start Thinking Afresh? Psychiatric Annals. 40: 88-91. DOI: 10.3928/00485718-20100127-04  0.318
2010 Peall K, Perera D, Blake DJ, Owen MJ, Morris HR. POMD10 Do psychiatric disorders form part of the myoclonus-dystonia syndrome phenotype? A systematic review of published literature Journal of Neurology, Neurosurgery, and Psychiatry. 81. DOI: 10.1136/Jnnp.2010.226340.170  0.347
2010 Sims R, Harold D, Gerrish A, Hollingworth P, Abraham R, Donovan MO, Owen M, Williams J. Mitochondrial genome-wide association study of Alzheimer's disease Alzheimers & Dementia. 6: 550. DOI: 10.1016/J.Jalz.2013.05.1070  0.316
2010 Cruchaga C, Kauwe JS, Mayo K, Bertelsen S, Nowotny P, Shah AR, Abraham R, Hollingworth P, Harold D, Owen MJ, Williams J, Lovestone S, Morris JC, Fagan AM, Holtzman DM, et al. SNPs associated with CSF tau levels modify rate of progression in Alzheimer's disease Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.612  0.567
2010 Reitz C, Cheng R, Rogaeva E, Lee J, Tokuhiro S, Bettens K, Sleegers K, Tan EK, Kimura R, Shibata N, Kamboh IM, Prince J, Maier W, Riemenschneider M, Owen M, et al. Meta-analysis of the association between SORL1 variants and Alzheimer's disease Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.351  0.356
2009 Azuma R, Daly EM, Campbell LE, Stevens AF, Deeley Q, Giampietro V, Brammer MJ, Glaser B, Ambery FZ, Morris RG, Williams SC, Owen MJ, Murphy DG, Murphy KC. Visuospatial working memory in children and adolescents with 22q11.2 deletion syndrome; an fMRI study. Journal of Neurodevelopmental Disorders. 1: 46-60. PMID 21547621 DOI: 10.1007/S11689-009-9008-9  0.324
2009 Carroll LS, Owen MJ. Genetic overlap between autism, schizophrenia and bipolar disorder. Genome Medicine. 1: 102. PMID 19886976 DOI: 10.1186/Gm102  0.438
2009 Liu Y, Chen G, Norton N, Liu W, Zhu H, Zhou P, Luan M, Yang S, Chen X, Carroll L, Williams NM, O'Donovan MC, Kirov G, Owen MJ. Whole genome association study in a homogenous population in Shandong peninsula of China reveals JARID2 as a susceptibility gene for schizophrenia. Journal of Biomedicine & Biotechnology. 2009: 536918. PMID 19884986 DOI: 10.1155/2009/536918  0.421
2009 McCarthy SE, Makarov V, Kirov G, Addington AM, McClellan J, Yoon S, Perkins DO, Dickel DE, Kusenda M, Krastoshevsky O, Krause V, Kumar RA, Grozeva D, Malhotra D, Walsh T, ... ... Owen MJ, et al. Microduplications of 16p11.2 are associated with schizophrenia. Nature Genetics. 41: 1223-7. PMID 19855392 DOI: 10.1038/Ng.474  0.384
2009 Fowler T, Langley K, Rice F, van den Bree MB, Ross K, Wilkinson LS, Owen MJ, O'Donovan MC, Thapar A. Psychopathy trait scores in adolescents with childhood ADHD: the contribution of genotypes affecting MAOA, 5HTT and COMT activity. Psychiatric Genetics. 19: 312-9. PMID 19829167 DOI: 10.1097/Ypg.0B013E3283328Df4  0.345
2009 Donohoe G, Walters J, Morris DW, Quinn EM, Judge R, Norton N, Giegling I, Hartmann AM, Möller HJ, Muglia P, Williams H, Moskvina V, Peel R, O'Donoghue T, Owen MJ, et al. Influence of NOS1 on verbal intelligence and working memory in both patients with schizophrenia and healthy control subjects. Archives of General Psychiatry. 66: 1045-54. PMID 19805695 DOI: 10.1001/Archgenpsychiatry.2009.139  0.38
2009 Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, ... ... Owen MJ, et al. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nature Genetics. 41: 1088-93. PMID 19734902 DOI: 10.1038/Ng.440  0.79
2009 Hamshere ML, Schulze TG, Schumacher J, Corvin A, Owen MJ, Jamra RA, Propping P, Maier W, Orozco y Diaz G, Mayoral F, Rivas F, Jones I, Jones L, Kirov G, Gill M, et al. Mood-incongruent psychosis in bipolar disorder: conditional linkage analysis shows genome-wide suggestive linkage at 1q32.3, 7p13 and 20q13.31. Bipolar Disorders. 11: 610-20. PMID 19689503 DOI: 10.1111/J.1399-5618.2009.00736.X  0.416
2009 Purcell SM, Wray NR, Stone JL, Visscher PM, O'Donovan MC, Sullivan PF, Ruderfer DM, McQuillin A, Morris DW, Oĝdushlaine CT, Corvin A, Holmans PA, Oĝdonovan MC, MacGregor S, Gurling H, ... ... Owen MJ, et al. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder Nature. 460: 748-752. PMID 19571811 DOI: 10.1038/Nature08185  0.412
2009 O'Donovan MC, Owen MJ. Genetics and the brain: many pathways to enlightenment. Human Genetics. 126: 1-2. PMID 19554351 DOI: 10.1007/S00439-009-0705-Y  0.355
2009 Holmans P, Green EK, Pahwa JS, Ferreira MA, Purcell SM, Sklar P, Owen MJ, O'Donovan MC, Craddock N. Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder. American Journal of Human Genetics. 85: 13-24. PMID 19539887 DOI: 10.1016/J.Ajhg.2009.05.011  0.354
2009 O'Donovan MC, Craddock NJ, Owen MJ. Genetics of psychosis; insights from views across the genome. Human Genetics. 126: 3-12. PMID 19521722 DOI: 10.1007/S00439-009-0703-0  0.438
2009 Sims R, Hollingworth P, Moskvina V, Dowzell K, O'Donovan MC, Powell J, Lovestone S, Brayne C, Rubinsztein D, Owen MJ, Williams J, Abraham R. Evidence that variation in the oligodendrocyte lineage transcription factor 2 (OLIG2) gene is associated with psychosis in Alzheimer's disease. Neuroscience Letters. 461: 54-9. PMID 19477230 DOI: 10.1016/J.Neulet.2009.05.051  0.326
2009 Williams HJ, Owen MJ, O'Donovan MC. Schizophrenia genetics: new insights from new approaches. British Medical Bulletin. 91: 61-74. PMID 19443537 DOI: 10.1093/Bmb/Ldp017  0.441
2009 Metlapally R, Li YJ, Tran-Viet KN, Abbott D, Czaja GR, Malecaze F, Calvas P, Mackey D, Rosenberg T, Paget S, Zayats T, Owen MJ, Guggenheim JA, Young TL. COL1A1 and COL2A1 genes and myopia susceptibility: evidence of association and suggestive linkage to the COL2A1 locus. Investigative Ophthalmology & Visual Science. 50: 4080-6. PMID 19387081 DOI: 10.1167/Iovs.08-3346  0.39
2009 Ng MY, Levinson DF, Faraone SV, Suarez BK, DeLisi LE, Arinami T, Riley B, Paunio T, Pulver AE, Irmansyah, Holmans PA, Escamilla M, Wildenauer DB, Williams NM, Laurent C, ... ... Owen MJ, et al. Meta-analysis of 32 genome-wide linkage studies of schizophrenia. Molecular Psychiatry. 14: 774-85. PMID 19349958 DOI: 10.1038/Mp.2008.135  0.39
2009 Owen MJ, Williams HJ, O'Donovan MC. Schizophrenia genetics: advancing on two fronts. Current Opinion in Genetics & Development. 19: 266-70. PMID 19345090 DOI: 10.1016/J.Gde.2009.02.008  0.423
2009 Craddock N, O'Donovan MC, Owen MJ. Psychosis genetics: modeling the relationship between schizophrenia, bipolar disorder, and mixed (or "schizoaffective") psychoses. Schizophrenia Bulletin. 35: 482-90. PMID 19329560 DOI: 10.1093/Schbul/Sbp020  0.432
2009 Yosifova A, Mushiroda T, Stoianov D, Vazharova R, Dimova I, Karachanak S, Zaharieva I, Milanova V, Madjirova N, Gerdjikov I, Tolev T, Velkova S, Kirov G, Owen MJ, O'Donovan MC, et al. Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population. Journal of Affective Disorders. 117: 87-97. PMID 19328558 DOI: 10.1016/J.Jad.2008.12.021  0.421
2009 Li YJ, Guggenheim JA, Bulusu A, Metlapally R, Abbott D, Malecaze F, Calvas P, Rosenberg T, Paget S, Creer RC, Kirov G, Owen MJ, Zhao B, White T, Mackey DA, et al. An international collaborative family-based whole-genome linkage scan for high-grade myopia. Investigative Ophthalmology & Visual Science. 50: 3116-27. PMID 19324860 DOI: 10.1167/Iovs.08-2781  0.379
2009 Abraham R, Sims R, Carroll L, Hollingworth P, O'Donovan MC, Williams J, Owen MJ. An association study of common variation at the MAPT locus with late-onset Alzheimer's disease. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 150: 1152-5. PMID 19308965 DOI: 10.1002/Ajmg.B.30951  0.387
2009 Holmans PA, Riley B, Pulver AE, Owen MJ, Wildenauer DB, Gejman PV, Mowry BJ, Laurent C, Kendler KS, Nestadt G, Williams NM, Schwab SG, Sanders AR, Nertney D, Mallet J, et al. Genomewide linkage scan of schizophrenia in a large multicenter pedigree sample using single nucleotide polymorphisms. Molecular Psychiatry. 14: 786-95. PMID 19223858 DOI: 10.1038/Mp.2009.11  0.407
2009 Kirov G, Grozeva D, Norton N, Ivanov D, Mantripragada KK, Holmans P, Craddock N, Owen MJ, O'Donovan MC. Support for the involvement of large copy number variants in the pathogenesis of schizophrenia. Human Molecular Genetics. 18: 1497-503. PMID 19181681 DOI: 10.1093/Hmg/Ddp043  0.383
2009 Cohen-Woods S, Gaysina D, Craddock N, Farmer A, Gray J, Gunasinghe C, Hoda F, Jones L, Knight J, Korszun A, Owen MJ, Sterne A, Craig IW, McGuffin P. Depression Case Control (DeCC) Study fails to support involvement of the muscarinic acetylcholine receptor M2 (CHRM2) gene in recurrent major depressive disorder. Human Molecular Genetics. 18: 1504-9. PMID 19181679 DOI: 10.1093/Hmg/Ddp051  0.355
2009 Williams HJ, Owen MJ, O'Donovan MC. New findings from genetic association studies of schizophrenia. Journal of Human Genetics. 54: 9-14. PMID 19158819 DOI: 10.1038/Jhg.2008.7  0.423
2009 Betcheva ET, Mushiroda T, Takahashi A, Kubo M, Karachanak SK, Zaharieva IT, Vazharova RV, Dimova II, Milanova VK, Tolev T, Kirov G, Owen MJ, O'Donovan MC, Kamatani N, Nakamura Y, et al. Case-control association study of 59 candidate genes reveals the DRD2 SNP rs6277 (C957T) as the only susceptibility factor for schizophrenia in the Bulgarian population. Journal of Human Genetics. 54: 98-107. PMID 19158809 DOI: 10.1038/Jhg.2008.14  0.44
2009 Carroll LS, Kendall K, O'Donovan MC, Owen MJ, Williams NM. Evidence that putative ADHD low risk alleles at SNAP25 may increase the risk of schizophrenia. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 150: 893-9. PMID 19132710 DOI: 10.1002/Ajmg.B.30915  0.419
2009 Moskvina V, Craddock N, Holmans P, Nikolov I, Pahwa JS, Green E, Owen MJ, O'Donovan MC. Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk. Molecular Psychiatry. 14: 252-60. PMID 19065143 DOI: 10.1038/Mp.2008.133  0.429
2009 Talkowski ME, McClain L, Allen T, Bradford LD, Calkins M, Edwards N, Georgieva L, Go R, Gur R, Gur R, Kirov G, Chowdari K, Kwentus J, Lyons P, Mansour H, ... ... Owen MJ, et al. Convergent patterns of association between phenylalanine hydroxylase variants and schizophrenia in four independent samples. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 150: 560-9. PMID 18937293 DOI: 10.1002/Ajmg.B.30862  0.392
2009 O'Donovan MC, Craddock N, Owen MJ. Strong evidence for multiple psychosis susceptibility genes - a rejoinder to Crow. Psychological Medicine. 39: 170-1. PMID 18845015 DOI: 10.1017/S0033291708004583  0.336
2009 O'Donovan MC, Norton N, Williams H, Peirce T, Moskvina V, Nikolov I, Hamshere M, Carroll L, Georgieva L, Dwyer S, Holmans P, Marchini JL, Spencer CC, Howie B, Leung HT, ... ... Owen MJ, et al. Analysis of 10 independent samples provides evidence for association between schizophrenia and a SNP flanking fibroblast growth factor receptor 2. Molecular Psychiatry. 14: 30-6. PMID 18813210 DOI: 10.1038/Mp.2008.108  0.427
2009 Langley K, Fowler TA, Grady DL, Moyzis RK, Holmans PA, van den Bree MB, Owen MJ, O'Donovan MC, Thapar A. Molecular genetic contribution to the developmental course of attention-deficit hyperactivity disorder. European Child & Adolescent Psychiatry. 18: 26-32. PMID 18563476 DOI: 10.1007/S00787-008-0698-4  0.321
2009 Morgan AR, Hollingworth P, Abraham R, Lovestone S, Brayne C, Rubinsztein DC, Lynch A, Lawlor B, Gill M, O'Donovan MC, Owen MJ, Williams J. Association analysis of dynamin-binding protein (DNMBP) on chromosome 10q with late onset Alzheimer's disease in a large caucasian UK sample. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 150: 61-4. PMID 18452187 DOI: 10.1002/Ajmg.B.30768  0.401
2009 Kirov G, Zaharieva I, Georgieva L, Moskvina V, Nikolov I, Cichon S, Hillmer A, Toncheva D, Owen MJ, O'Donovan MC. A genome-wide association study in 574 schizophrenia trios using DNA pooling. Molecular Psychiatry. 14: 796-803. PMID 18332876 DOI: 10.1038/Mp.2008.33  0.408
2009 Proitsi P, Lupton M, Reeves S, Hamilton G, Archer N, Martin B, hollingworth P, Lawlord B, Gill M, Owen MJ, Williams J, Lovestone S, Powell J. Genes of the serotonergic and dopaminergic pathways and their interaction affect the expression of Behavioural and Psychological Symptoms in Dementia (BPSD). Nature Precedings. DOI: 10.1038/Npre.2009.3896.1  0.313
2009 Harold D, Hollingworth P, Hamshere M, Holmans P, Abraham R, Sims R, Gerrish A, Lovestone S, Brayne C, Gill M, Lawlor B, Passmore P, Nothen M, Maier W, Livingston G, ... ... Owen M, et al. P4-133: Genome-wide association study of age at onset of Alzheimer's disease Alzheimer's & Dementia. 5: P471-P471. DOI: 10.1016/J.Jalz.2009.04.801  0.561
2009 Gerrish A, Harold D, Sims R, Abraham R, Hollingworth P, Hamshere M, Lovestone S, Brayne C, Gill M, Lawlor B, Passmore P, Nothen M, Mayer W, Livingston G, Bass N, ... ... Owen M, et al. P4-124: An examination of previously reported Alzheimer candidate genes within a large genome-wide association dataset Alzheimer's & Dementia. 5: P468-P468. DOI: 10.1016/J.Jalz.2009.04.792  0.541
2009 Hollingworth P, Sims R, Abraham R, Harold D, Gerrish A, Hamshere M, Lovestone S, Brayne C, Gill M, Lawlor B, Passmore P, Nothen M, Mayer W, Livingston G, Bass N, ... ... Owen M, et al. P4-121: Genome-wide association study of Alzheimer's with psychotic symptoms Alzheimer's & Dementia. 5: P467-P467. DOI: 10.1016/J.Jalz.2009.04.789  0.52
2009 Sims R, Hollingworth P, Abraham R, Harold D, Holmans P, Lovestone S, Powell J, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Craig D, Passmore P, Nöthen M, Mayer W, ... ... Owen M, et al. P4-120: Investigating psychosis candidate genes in Alzheimer's disease with psychosis using genome-wide association studies Alzheimer's & Dementia. 5: P466-P467. DOI: 10.1016/J.Jalz.2009.04.788  0.648
2008 O'Donovan MC, Kirov G, Owen MJ. Phenotypic variations on the theme of CNVs. Nature Genetics. 40: 1392-3. PMID 19029974 DOI: 10.1038/Ng1208-1392  0.387
2008 Kwok JB, Loy CT, Hamilton G, Lau E, Hallupp M, Williams J, Owen MJ, Broe GA, Tang N, Lam L, Powell JF, Lovestone S, Schofield PR. Glycogen synthase kinase-3beta and tau genes interact in Alzheimer's disease. Annals of Neurology. 64: 446-54. PMID 18991351 DOI: 10.1002/Ana.21476  0.344
2008 Abraham R, Moskvina V, Sims R, Hollingworth P, Morgan A, Georgieva L, Dowzell K, Cichon S, Hillmer AM, O'Donovan MC, Williams J, Owen MJ, Kirov G. A genome-wide association study for late-onset Alzheimer's disease using DNA pooling. Bmc Medical Genomics. 1: 44. PMID 18823527 DOI: 10.1186/1755-8794-1-44  0.408
2008 Ferreira MA, O'Donovan MC, Meng YA, Jones IR, Ruderfer DM, Jones L, Fan J, Kirov G, Perlis RH, Green EK, Smoller JW, Grozeva D, Stone J, Nikolov I, Chambert K, ... ... Owen MJ, et al. Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nature Genetics. 40: 1056-8. PMID 18711365 DOI: 10.1038/Ng.209  0.371
2008 Williams NM, Williams H, Majounie E, Norton N, Glaser B, Morris HR, Owen MJ, O'Donovan MC. Analysis of copy number variation using quantitative interspecies competitive PCR. Nucleic Acids Research. 36: e112. PMID 18697816 DOI: 10.1093/Nar/Gkn495  0.359
2008 O'Donovan MC, Craddock N, Norton N, Williams H, Peirce T, Moskvina V, Nikolov I, Hamshere M, Carroll L, Georgieva L, Dwyer S, Holmans P, Marchini JL, Spencer CC, Howie B, ... ... Owen MJ, et al. Identification of loci associated with schizophrenia by genome-wide association and follow-up. Nature Genetics. 40: 1053-5. PMID 18677311 DOI: 10.1038/Ng.201  0.388
2008 Stone JL, O'Donovan MC, Gurling H, Kirov GK, Blackwood DHR, Corvin A, Craddock NJ, Gill M, Hultman CM, Lichtenstein P, McQuillin A, Pato CN, Ruderfer DM, Owen MJ, St Clair D, et al. Rare chromosomal deletions and duplications increase risk of schizophrenia Nature. 455: 237-241. PMID 18668038 DOI: 10.1038/Nature07239  0.424
2008 O'Donovan MC, Craddock N, Owen MJ. Schizophrenia: complex genetics, not fairy tales. Psychological Medicine. 38: 1697-9; discussion 1. PMID 18578899 DOI: 10.1017/S0033291708003802  0.343
2008 Craddock N, O'Donovan MC, Owen MJ. Genome-wide association studies in psychiatry: lessons from early studies of non-psychiatric and psychiatric phenotypes. Molecular Psychiatry. 13: 649-53. PMID 18504426 DOI: 10.1038/Mp.2008.45  0.346
2008 Owen MJ. Schizophrenia aetiology: Do gene-environment interactions hold the key? [Comment] Schizophrenia Research. PMID 18499402 DOI: 10.1016/J.Schres.2008.04.003  0.335
2008 Georgieva L, Dimitrova A, Ivanov D, Nikolov I, Williams NM, Grozeva D, Zaharieva I, Toncheva D, Owen MJ, Kirov G, O'Donovan MC. Support for neuregulin 1 as a susceptibility gene for bipolar disorder and schizophrenia. Biological Psychiatry. 64: 419-27. PMID 18466881 DOI: 10.1016/J.Biopsych.2008.03.025  0.442
2008 Zaharieva I, Georgieva L, Nikolov I, Kirov G, Owen MJ, O'Donovan MC, Toncheva D. Association study in the 5q31-32 linkage region for schizophrenia using pooled DNA genotyping. Bmc Psychiatry. 8: 11. PMID 18298822 DOI: 10.1186/1471-244X-8-11  0.395
2008 Shifman S, Johannesson M, Bronstein M, Chen SX, Collier DA, Craddock NJ, Kendler KS, Li T, O'Donovan M, O'Neill FA, Owen MJ, Walsh D, Weinberger DR, Sun C, Flint J, et al. Genome-wide association identifies a common variant in the reelin gene that increases the risk of schizophrenia only in women. Plos Genetics. 4: e28. PMID 18282107 DOI: 10.1371/Journal.Pgen.0040028  0.396
2008 Hayesmoore JB, Bray NJ, Owen MJ, O'Donovan MC. DISC1 mRNA expression is not influenced by common Cis-acting regulatory polymorphisms or imprinting. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 147: 1065-9. PMID 18270998 DOI: 10.1002/Ajmg.B.30715  0.401
2008 Caspi A, Langley K, Milne B, Moffitt TE, O'Donovan M, Owen MJ, Polo Tomas M, Poulton R, Rutter M, Taylor A, Williams B, Thapar A. A replicated molecular genetic basis for subtyping antisocial behavior in children with attention-deficit/hyperactivity disorder. Archives of General Psychiatry. 65: 203-10. PMID 18250258 DOI: 10.1001/Archgenpsychiatry.2007.24  0.305
2008 Bray NJ, Holmans PA, van den Bree MB, Jones L, Elliston LA, Hughes G, Richards AL, Williams NM, Craddock N, Owen MJ, O'Donovan MC. Cis- and trans- loci influence expression of the schizophrenia susceptibility gene DTNBP1. Human Molecular Genetics. 17: 1169-74. PMID 18182443 DOI: 10.1093/Hmg/Ddn006  0.427
2008 Gaysina D, Cohen S, Craddock N, Farmer A, Hoda F, Korszun A, Owen MJ, Craig IW, McGuffin P. No association with the 5,10-methylenetetrahydrofolate reductase gene and major depressive disorder: results of the depression case control (DeCC) study and a meta-analysis. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 147: 699-706. PMID 18165972 DOI: 10.1002/Ajmg.B.30665  0.359
2008 Morgan AR, Hamilton G, Turic D, Jehu L, Harold D, Abraham R, Hollingworth P, Moskvina V, Brayne C, Rubinsztein DC, Lynch A, Lawlor B, Gill M, O'Donovan M, Powell J, ... ... Owen MJ, et al. Association analysis of 528 intra-genic SNPs in a region of chromosome 10 linked to late onset Alzheimer's disease. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 147: 727-31. PMID 18163421 DOI: 10.1002/Ajmg.B.30670  0.431
2008 Blom ES, Holmans P, Arepalli S, Adighibe O, Hamshere ML, Gatz M, Pedersen NL, Bergem AL, Owen MJ, Hollingworth P, Goate A, Williams J, Lannfelt L, Hardy J, Wavrant-De Vrièze F, et al. Does APOE explain the linkage of Alzheimer's disease to chromosome 19q13? American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 147: 778-83. PMID 18161859 DOI: 10.1002/Ajmg.B.30681  0.607
2008 Li Y, Grupe A, Rowland C, Holmans P, Segurado R, Abraham R, Jones L, Catanese J, Ross D, Mayo K, Martinez M, Hollingworth P, Goate A, Cairns NJ, Racette BA, ... ... Owen MJ, et al. Evidence that common variation in NEDD9 is associated with susceptibility to late-onset Alzheimer's and Parkinson's disease. Human Molecular Genetics. 17: 759-67. PMID 18063669 DOI: 10.1093/Hmg/Ddm348  0.58
2008 Talkowski ME, Kirov G, Bamne M, Georgieva L, Torres G, Mansour H, Chowdari KV, Milanova V, Wood J, McClain L, Prasad K, Shirts B, Zhang J, O'Donovan MC, Owen MJ, et al. A network of dopaminergic gene variations implicated as risk factors for schizophrenia. Human Molecular Genetics. 17: 747-58. PMID 18045777 DOI: 10.1093/Hmg/Ddm347  0.366
2008 Williams NM, Glaser B, Norton N, Williams H, Pierce T, Moskvina V, Monks S, Del Favero J, Goossens D, Rujescu D, Giegling I, Kirov G, Craddock N, Murphy KC, O'Donovan MC, ... Owen MJ, et al. Strong evidence that GNB1L is associated with schizophrenia. Human Molecular Genetics. 17: 555-66. PMID 18003636 DOI: 10.1093/Hmg/Ddm330  0.445
2008 Li H, Wetten S, Li L, St Jean PL, Upmanyu R, Surh L, Hosford D, Barnes MR, Briley JD, Borrie M, Coletta N, Delisle R, Dhalla D, Ehm MG, Feldman HH, ... ... Owen MJ, et al. Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease. Archives of Neurology. 65: 45-53. PMID 17998437 DOI: 10.1001/Archneurol.2007.3  0.409
2008 Kirov G, Gumus D, Chen W, Norton N, Georgieva L, Sari M, O'Donovan MC, Erdogan F, Owen MJ, Ropers HH, Ullmann R. Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia. Human Molecular Genetics. 17: 458-65. PMID 17989066 DOI: 10.1093/Hmg/Ddm323  0.383
2008 Li Y, Rowland C, Catanese J, Morris J, Lovestone S, O'Donovan MC, Goate A, Owen M, Williams J, Grupe A. SORL1 variants and risk of late-onset Alzheimer's disease. Neurobiology of Disease. 29: 293-6. PMID 17949987 DOI: 10.1016/J.Nbd.2007.09.001  0.567
2008 Buxbaum JD, Georgieva L, Young JJ, Plescia C, Kajiwara Y, Jiang Y, Moskvina V, Norton N, Peirce T, Williams H, Craddock NJ, Carroll L, Corfas G, Davis KL, Owen MJ, et al. Molecular dissection of NRG1-ERBB4 signaling implicates PTPRZ1 as a potential schizophrenia susceptibility gene. Molecular Psychiatry. 13: 162-72. PMID 17579610 DOI: 10.1038/Sj.Mp.4001991  0.393
2008 Craddock NJ, Owen MJ. Is there an inverse relationship between Down's syndrome and bipolar affective disorder? Literature review and genetic implications Journal of Intellectual Disability Research. 38: 613-620. PMID 7881232 DOI: 10.1111/J.1365-2788.1994.Tb00462.X  0.362
2008 Nicholas B, Owen MJ, Wimpory DC, Caspari T. Autism-associated SNPs in the clock genes npas2 , per1 and the homeobox gene en2 alter DNA sequences that show characteristics of microRNA genes. Nature Precedings. 1-1. DOI: 10.1038/Npre.2008.2366.1  0.347
2008 Williams J, Abraham R, Morgan A, Sims R, Hollingworth P, O'Donovan M, Owen M, Holmans P, Nikolov I, Moskvina V, Lovestone S, Rubinsztein D, Brayne C, Gill M, Lawlor B, et al. O2-06-01: A powerful, genome-wide association scan for susceptibility genes for late-onset Alzheimer's disease Alzheimer's & Dementia. 4: T143-T143. DOI: 10.1016/J.Jalz.2008.05.349  0.529
2008 Sims R, Hollingworth P, Morgan A, Dowzell K, Stretton A, Jones L, Norton N, Williams H, Georgieva L, Moskvina V, Nikolov I, Hamshere M, Holmans P, Lovestone S, Brayne C, ... ... Owen M, et al. P3-265: Testing for association between Alzheimer's disease with psychosis and variants identified as influencing risk of schizophrenia Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1833  0.411
2008 Morgan AR, Abraham R, Hollingworth P, Lovestone S, Brayne C, Rubinsztein DC, O'Donovan M, Owen MJ, Williams J. P3-245: Association analysis of tau and progranulin with late-onset Alzheimer's disease in a large caucasian U.K. sample Alzheimer's & Dementia. 4: T592-T593. DOI: 10.1016/J.Jalz.2008.05.1812  0.331
2008 Abraham R, Georgieva L, Sims R, Morgan A, Hollingworth P, Lovestone S, Brayne C, Cichon S, O'Donovan M, Williams J, Owen M, Kirov G. P3-196: A genome-wide association study for late-onset Alzheimer's disease using DNA pooling Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1762  0.351
2008 Hollingworth P, Dowzell K, Williams A, Keates S, Abraham R, Morgan A, Foy C, Archer N, Powell J, Lovestone S, O'Donavan M, Owen MJ, Williams J. P3-016: The APOE-ϵ4 allele does not affect rate of cognitive and functional decline in late-onset Alzheimer's disease (AD): Findings from the U.K. Medical Research Council (MRC) genetic resource for AD Alzheimer's & Dementia. 4: T521-T521. DOI: 10.1016/J.Jalz.2008.05.1579  0.329
2007 Hamilton G, Proitsi P, Williams J, O'Donovan M, Owen M, Powell J, Lovestone S. Complement factor H Y402H polymorphism is not associated with late-onset Alzheimer's disease. Neuromolecular Medicine. 9: 331-4. PMID 17999207 DOI: 10.1007/S12017-007-8013-Y  0.393
2007 Zammit S, Spurlock G, Williams H, Norton N, Williams N, O'Donovan MC, Owen MJ. Genotype effects of CHRNA7, CNR1 and COMT in schizophrenia: interactions with tobacco and cannabis use. The British Journal of Psychiatry : the Journal of Mental Science. 191: 402-7. PMID 17978319 DOI: 10.1192/Bjp.Bp.107.036129  0.35
2007 Burton PR, Clayton DG, Cardon LR, Craddock N, Deloukas P, Duncanson A, Kwiatkowski DP, McCarthy MI, Ouwehand WH, Samani NJ, Todd JA, Donnelly P, Barrett JC, ... ... Owen MJ, et al. Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nature Genetics. 39: 1329-37. PMID 17952073 DOI: 10.1038/Ng.2007.17  0.365
2007 Williams HJ, Norton N, Peirce T, Dwyer S, Williams NM, Moskvina V, Owen MJ, O'Donovan MC. Association analysis of the glial cell line-derived neurotrophic factor (GDNF) gene in schizophrenia. Schizophrenia Research. 97: 271-6. PMID 17897812 DOI: 10.1016/j.schres.2007.09.004  0.337
2007 Walters JT, Owen MJ. Endophenotypes in psychiatric genetics. Molecular Psychiatry. 12: 886-90. PMID 17895920 DOI: 10.1038/Sj.Mp.4002068  0.32
2007 Hamshere ML, Holmans PA, Avramopoulos D, Bassett SS, Blacker D, Bertram L, Wiener H, Rochberg N, Tanzi RE, Myers A, Wavrant-De Vrièze F, Go R, Fallin D, Lovestone S, Hardy J, ... ... Owen MJ, et al. Genome-wide linkage analysis of 723 affected relative pairs with late-onset Alzheimer's disease. Human Molecular Genetics. 16: 2703-12. PMID 17725986 DOI: 10.1093/Hmg/Ddm224  0.633
2007 Jones I, Hamshere M, Nangle JM, Bennett P, Green E, Heron J, Segurado R, Lambert D, Holmans P, Corvin A, Owen M, Jones L, Gill M, Craddock N. Bipolar affective puerperal psychosis: genome-wide significant evidence for linkage to chromosome 16. The American Journal of Psychiatry. 164: 1099-104. PMID 17606662 DOI: 10.1176/Appi.Ajp.164.7.1099  0.396
2007 Owen MJ, Craddock N, Jablensky A. The genetic deconstruction of psychosis. Schizophrenia Bulletin. 33: 905-11. PMID 17551090 DOI: 10.1093/Schbul/Sbm053  0.424
2007 Thapar A, Langley K, Owen MJ, O'Donovan MC. Advances in genetic findings on attention deficit hyperactivity disorder. Psychological Medicine. 37: 1681-92. PMID 17506925 DOI: 10.1017/S0033291707000773  0.345
2007 Hollingworth P, Hamshere ML, Holmans PA, O'Donovan MC, Sims R, Powell J, Lovestone S, Myers A, DeVrieze FW, Hardy J, Goate A, Owen M, Williams J. Increased familial risk and genomewide significant linkage for Alzheimer's disease with psychosis. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 144: 841-8. PMID 17492769 DOI: 10.1002/Ajmg.B.30515  0.636
2007 Hamilton G, Proitsi P, Jehu L, Morgan A, Williams J, O'Donovan MC, Owen MJ, Powell JF, Lovestone S. Candidate gene association study of insulin signaling genes and Alzheimer's disease: evidence for SOS2, PCK1, and PPARgamma as susceptibility loci. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 144: 508-16. PMID 17440948 DOI: 10.1002/Ajmg.B.30503  0.424
2007 Harold D, Jehu L, Turic D, Hollingworth P, Moore P, Summerhayes P, Moskvina V, Foy C, Archer N, Hamilton BA, Lovestone S, Powell J, Brayne C, Rubinsztein DC, Jones L, ... ... Owen MJ, et al. Interaction between the ADAM12 and SH3MD1 genes may confer susceptibility to late-onset Alzheimer's disease. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 144: 448-52. PMID 17440933 DOI: 10.1002/Ajmg.B.30456  0.382
2007 Williams HJ, Owen MJ, O'Donovan MC. Is COMT a susceptibility gene for schizophrenia? Schizophrenia Bulletin. 33: 635-41. PMID 17412710 DOI: 10.1093/Schbul/Sbm019  0.399
2007 Craddock N, O'Donovan MC, Owen MJ. Symptom dimensions and the Kraepelinian dichotomy. The British Journal of Psychiatry : the Journal of Mental Science. 190: 361; author reply 36. PMID 17401047 DOI: 10.1192/Bjp.190.4.361  0.31
2007 Norton N, Williams HJ, Dwyer S, Carroll L, Peirce T, Moskvina V, Segurado R, Nikolov I, Williams NM, Ikeda M, Iwata N, Owen MJ, O'Donovan MC. Association analysis of AKT1 and schizophrenia in a UK case control sample. Schizophrenia Research. 93: 58-65. PMID 17383860 DOI: 10.1016/J.Schres.2007.02.006  0.419
2007 Morgan AR, Turic D, Jehu L, Hamilton G, Hollingworth P, Moskvina V, Jones L, Lovestone S, Brayne C, Rubinsztein DC, Lawlor B, Gill M, O'Donovan MC, Owen MJ, Williams J. Association studies of 23 positional/functional candidate genes on chromosome 10 in late-onset Alzheimer's disease. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 144: 762-70. PMID 17373700 DOI: 10.1002/Ajmg.B.30509  0.404
2007 Craddock N, O'Donovan MC, Owen MJ. Phenotypic and genetic complexity of psychosis. Invited commentary on ... Schizophrenia: a common disease caused by multiple rare alleles. The British Journal of Psychiatry : the Journal of Mental Science. 190: 200-3. PMID 17329738 DOI: 10.1192/Bjp.Bp.106.033761  0.384
2007 Grupe A, Abraham R, Li Y, Rowland C, Hollingworth P, Morgan A, Jehu L, Segurado R, Stone D, Schadt E, Karnoub M, Nowotny P, Tacey K, Catanese J, Sninsky J, ... ... Owen MJ, et al. Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants. Human Molecular Genetics. 16: 865-73. PMID 17317784 DOI: 10.1093/Hmg/Ddm031  0.582
2007 Gaughran F, Blizard R, Mohan R, Zammit S, Owen M. Birth order and the severity of illness in schizophrenia. Psychiatry Research. 150: 205-10. PMID 17292486 DOI: 10.1016/J.Psychres.2006.05.012  0.365
2007 Le Hellard S, Lee AJ, Underwood S, Thomson PA, Morris SW, Torrance HS, Anderson SM, Adams RR, Navarro P, Christoforou A, Houlihan LM, Detera-Wadleigh S, Owen MJ, Asherson P, Muir WJ, et al. Haplotype analysis and a novel allele-sharing method refines a chromosome 4p locus linked to bipolar affective disorder. Biological Psychiatry. 61: 797-805. PMID 16996484 DOI: 10.1016/J.Biopsych.2006.06.029  0.41
2006 Harold D, Paracchini S, Scerri T, Dennis M, Cope N, Hill G, Moskvina V, Walter J, Richardson AJ, Owen MJ, Stein JF, Green ED, O'Donovan MC, Williams J, Monaco AP. Further evidence that the KIAA0319 gene confers susceptibility to developmental dyslexia. Molecular Psychiatry. 11: 1085-91, 1061. PMID 17033633 DOI: 10.1038/Sj.Mp.4001904  0.417
2006 Hollingworth P, Hamshere ML, Moskvina V, Dowzell K, Moore PJ, Foy C, Archer N, Lynch A, Lovestone S, Brayne C, Rubinsztein DC, Lawlor B, Gill M, Owen MJ, Williams J. Four components describe behavioral symptoms in 1,120 individuals with late-onset Alzheimer's disease. Journal of the American Geriatrics Society. 54: 1348-54. PMID 16970641 DOI: 10.1111/J.1532-5415.2006.00854.X  0.313
2006 Green EK, Norton N, Peirce T, Grozeva D, Kirov G, Owen MJ, O'Donovan MC, Craddock N. Evidence that a DISC1 frame-shift deletion associated with psychosis in a single family may not be a pathogenic mutation. Molecular Psychiatry. 11: 798-9. PMID 16936759 DOI: 10.1038/Sj.Mp.4001853  0.354
2006 Georgieva L, Moskvina V, Peirce T, Norton N, Bray NJ, Jones L, Holmans P, Macgregor S, Zammit S, Wilkinson J, Williams H, Nikolov I, Williams N, Ivanov D, Davis KL, ... ... Owen MJ, et al. Convergent evidence that oligodendrocyte lineage transcription factor 2 (OLIG2) and interacting genes influence susceptibility to schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 103: 12469-74. PMID 16891421 DOI: 10.1073/Pnas.0603029103  0.394
2006 Glaser B, Moskvina V, Kirov G, Murphy KC, Williams H, Williams N, Owen MJ, O'Donovan MC. Analysis of ProDH, COMT and ZDHHC8 risk variants does not support individual or interactive effects on schizophrenia susceptibility. Schizophrenia Research. 87: 21-7. PMID 16860541 DOI: 10.1016/J.Schres.2006.05.024  0.418
2006 Li Y, Grupe A, Rowland C, Nowotny P, Kauwe JS, Smemo S, Hinrichs A, Tacey K, Toombs TA, Kwok S, Catanese J, White TJ, Maxwell TJ, Hollingworth P, Abraham R, ... ... Owen M, et al. DAPK1 variants are associated with Alzheimer's disease and allele-specific expression. Human Molecular Genetics. 15: 2560-8. PMID 16847012 DOI: 10.1093/Hmg/Ddl178  0.624
2006 Li D, Sham PC, Owen MJ, He L. Meta-analysis shows significant association between dopamine system genes and attention deficit hyperactivity disorder (ADHD). Human Molecular Genetics. 15: 2276-84. PMID 16774975 DOI: 10.1093/Hmg/Ddl152  0.334
2006 Williams NM, O'Donovan MC, Owen MJ. Chromosome 22 deletion syndrome and schizophrenia. International Review of Neurobiology. 73: 1-27. PMID 16737900 DOI: 10.1016/S0074-7742(06)73001-X  0.393
2006 Thapar A, Langley K, O'donovan M, Owen M. Refining the attention deficit hyperactivity disorder phenotype for molecular genetic studies. Molecular Psychiatry. 11: 714-20. PMID 16702977 DOI: 10.1038/Sj.Mp.4001831  0.32
2006 Paylor R, Glaser B, Mupo A, Ataliotis P, Spencer C, Sobotka A, Sparks C, Choi CH, Oghalai J, Curran S, Murphy KC, Monks S, Williams N, O'Donovan MC, Owen MJ, et al. Tbx1 haploinsufficiency is linked to behavioral disorders in mice and humans: implications for 22q11 deletion syndrome. Proceedings of the National Academy of Sciences of the United States of America. 103: 7729-34. PMID 16684884 DOI: 10.1073/Pnas.0600206103  0.395
2006 Talkowski ME, Seltman H, Bassett AS, Brzustowicz LM, Chen X, Chowdari KV, Collier DA, Cordeiro Q, Corvin AP, Deshpande SN, Egan MF, Gill M, Kendler KS, Kirov G, Heston LL, ... ... Owen MJ, et al. Evaluation of a susceptibility gene for schizophrenia: genotype based meta-analysis of RGS4 polymorphisms from thirteen independent samples. Biological Psychiatry. 60: 152-62. PMID 16631129 DOI: 10.1016/J.Biopsych.2006.02.015  0.423
2006 Norton N, Williams HJ, Owen MJ. An update on the genetics of schizophrenia. Current Opinion in Psychiatry. 19: 158-64. PMID 16612196 DOI: 10.1097/01.Yco.0000214341.52249.59  0.43
2006 Williams NM, Green EK, Macgregor S, Dwyer S, Norton N, Williams H, Raybould R, Grozeva D, Hamshere M, Zammit S, Jones L, Cardno A, Kirov G, Jones I, O'Donovan MC, ... Owen MJ, et al. Variation at the DAOA/G30 locus influences susceptibility to major mood episodes but not psychosis in schizophrenia and bipolar disorder. Archives of General Psychiatry. 63: 366-73. PMID 16585465 DOI: 10.1001/Archpsyc.63.4.366  0.398
2006 Hamilton G, Samedi F, Knight J, Archer N, Foy C, Walter S, Turic D, Jehu L, Moore P, Hollingworth P, O'Donovan MC, Williams J, Owen MJ, Lovestone S, Powell JF. Polymorphisms in the phosphate and tensin homolog gene are not associated with late-onset Alzheimer's disease. Neuroscience Letters. 401: 77-80. PMID 16574322 DOI: 10.1016/J.Neulet.2006.03.021  0.409
2006 Zammit S, Owen MJ. Stressful life events, 5-HTT genotype and risk of depression. The British Journal of Psychiatry : the Journal of Mental Science. 188: 199-201. PMID 16507957 DOI: 10.1192/Bjp.Bp.105.020644  0.302
2006 Craddock N, Owen MJ, O'Donovan MC. The catechol-O-methyl transferase (COMT) gene as a candidate for psychiatric phenotypes: evidence and lessons. Molecular Psychiatry. 11: 446-58. PMID 16505837 DOI: 10.1038/Sj.Mp.4001808  0.38
2006 Kirov G, Nikolov I, Georgieva L, Moskvina V, Owen MJ, O'Donovan MC. Pooled DNA genotyping on Affymetrix SNP genotyping arrays. Bmc Genomics. 7: 27. PMID 16480507 DOI: 10.1186/1471-2164-7-27  0.329
2006 Harold D, Macgregor S, Patterson CE, Hollingworth P, Moore P, Owen MJ, Williams J, O'Donovan M, Passmore P, McIlroy S, Jones L. A single nucleotide polymorphism in CHAT influences response to acetylcholinesterase inhibitors in Alzheimer's disease. Pharmacogenetics and Genomics. 16: 75-7. PMID 16424819 DOI: 10.1097/01.Fpc.0000189799.88596.04  0.335
2006 Blair IP, Chetcuti AF, Badenhop RF, Scimone A, Moses MJ, Adams LJ, Craddock N, Green E, Kirov G, Owen MJ, Kwok JB, Donald JA, Mitchell PB, Schofield PR. Positional cloning, association analysis and expression studies provide convergent evidence that the cadherin gene FAT contains a bipolar disorder susceptibility allele. Molecular Psychiatry. 11: 372-83. PMID 16402135 DOI: 10.1002/Ajmg.B.30233  0.387
2006 Peirce TR, Bray NJ, Williams NM, Norton N, Moskvina V, Preece A, Haroutunian V, Buxbaum JD, Owen MJ, O'Donovan MC. Convergent evidence for 2',3'-cyclic nucleotide 3'-phosphodiesterase as a possible susceptibility gene for schizophrenia. Archives of General Psychiatry. 63: 18-24. PMID 16389193 DOI: 10.1001/Archpsyc.63.1.18  0.422
2006 Green EK, Raybould R, Macgregor S, Hyde S, Young AH, O'Donovan MC, Owen MJ, Kirov G, Jones L, Jones I, Craddock N. Genetic variation of brain-derived neurotrophic factor (BDNF) in bipolar disorder: case-control study of over 3000 individuals from the UK. The British Journal of Psychiatry : the Journal of Mental Science. 188: 21-5. PMID 16388065 DOI: 10.1192/Bjp.Bp.105.009969  0.41
2006 Grupe A, Li Y, Rowland C, Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell TJ, Cherny S, Doil L, Tacey K, van Luchene R, Myers A, Wavrant-De Vrièze F, Kaleem M, ... ... Owen M, et al. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. American Journal of Human Genetics. 78: 78-88. PMID 16385451 DOI: 10.1086/498851  0.609
2006 Craddock N, O'Donovan MC, Owen MJ. Genes for schizophrenia and bipolar disorder? Implications for psychiatric nosology. Schizophrenia Bulletin. 32: 9-16. PMID 16319375 DOI: 10.1093/Schbul/Sbj033  0.424
2006 Smemo S, Nowotny P, Hinrichs AL, Kauwe JS, Cherny S, Erickson K, Myers AJ, Kaleem M, Marlowe L, Gibson AM, Hollingworth P, O'Donovan MC, Morris CM, Holmans P, Lovestone S, ... ... Owen MJ, et al. Ubiquilin 1 polymorphisms are not associated with late-onset Alzheimer's disease. Annals of Neurology. 59: 21-6. PMID 16278862 DOI: 10.1002/Ana.20673  0.632
2006 Norton N, Moskvina V, Morris DW, Bray NJ, Zammit S, Williams NM, Williams HJ, Preece AC, Dwyer S, Wilkinson JC, Spurlock G, Kirov G, Buckland P, Waddington JL, Gill M, ... ... Owen MJ, et al. Evidence that interaction between neuregulin 1 and its receptor erbB4 increases susceptibility to schizophrenia. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 141: 96-101. PMID 16249994 DOI: 10.1002/Ajmg.B.30236  0.412
2006 Hamshere ML, Williams NM, Norton N, Williams H, Cardno AG, Zammit S, Jones LA, Murphy KC, Sanders RD, McCarthy G, Gray MY, Jones G, Holmans P, O'Donovan MC, Owen MJ, et al. Genome wide significant linkage in schizophrenia conditioning on occurrence of depressive episodes. Journal of Medical Genetics. 43: 563-7. PMID 16227524 DOI: 10.1136/Jmg.2005.035345  0.363
2006 Zammit S, Lewis G, Thapar A, Owen R, Jones G, Jones S, Sanders R, Milham C, Mahdi A, O'Donovan MC, Owen MJ. Phenotypic variation between parent-offspring trios and non-trios in genetic studies of schizophrenia. Journal of Psychiatric Research. 40: 622-6. PMID 16038933 DOI: 10.1016/J.Jpsychires.2005.05.006  0.388
2006 Owen MJ. Genes and behavior: nature-nurture interplay explained British Journal of Psychiatry. 189: 192-193. DOI: 10.1192/Bjp.189.2.192  0.305
2006 Grupe A, Li Y, Rowland C, Hinrichs T, Holmans P, Hardy J, O'Donovan M, Owen MJ, Williams J, Goate A. Reply to Bertram et al. [2] American Journal of Human Genetics. 79: 183-184. DOI: 10.1086/505033  0.592
2006 Harold D, Paracchini S, Scerri T, Dennis M, Cope N, Hill G, Moskvina V, Walter J, Richardson AJ, Owen MJ, Stein JF, Green ED, O'Donovan MC, Williams J, Monaco AP. Linkage disequilibrium structure of KIAA0319 and DCDC2, two candidate susceptibility genes for developmental dyslexia Molecular Psychiatry. 11: 1061. DOI: 10.1038/Sj.Mp.4001930  0.316
2006 Lambert D, Middle F, Hamshere ML, Segurado R, Raybould R, Corvin A, Green E, O'Mahony E, Nikolov I, Mulcahy T, Haque S, Bort S, Bennett P, Norton N, Owen MJ, et al. Stage 2 of the Wellcome Trust UK–Irish bipolar affective disorder sibling-pair genome screen: evidence for linkage on chromosomes 6q16–q21, 4q12–q21, 9p21, 10p14–p12 and 18q22 - Corrigendum Molecular Psychiatry. DOI: 10.1038/Sj.Mp.4001917  0.337
2006 Abraham R, Morgan AR, Jehu L, Turic D, Hamilton G, Hollingworth P, Moore P, Dowzell K, Holmans P, Moskvina V, Cope N, Powell J, Lovestone S, Brayne C, Rubinsztein DC, ... ... Owen MJ, et al. P1-335: A powerful association analysis of 496 SNPs in 80 positional candidate genes in a linked region on chromosome 10 for association with late onset Alzheimer's disease Alzheimer's & Dementia. 2: S195-S195. DOI: 10.1016/J.Jalz.2006.05.713  0.465
2006 Kwok JB, Hallupp M, Loy CT, Harold DH, Williams J, Owen MJ, Lovestone S, Powell J, Broe GA, Schofield PR. P1-332: Glycogen synthase kinase -3 beta polymorphisms interact with Tau haplotypes in Alzheimer's disease Alzheimer's & Dementia. 2: S194-S195. DOI: 10.1016/J.Jalz.2006.05.710  0.306
2006 Hollingworth P, Hamshere M, Holmans P, Jones L, O'Donavan M, Myers A, Hardy J, Goate A, Lovestone S, Owen M, Williams J. P1-331: Familiality and linkage analysis of behavioral symptoms and age at disease onset in late-onset Alzheimer's disease Alzheimer's & Dementia. 2: S194-S194. DOI: 10.1016/J.Jalz.2006.05.709  0.598
2006 Sims R, Hollingworth P, Cope N, Jehu L, Morgan A, Moskvina V, Lovestone S, Brayne C, Rubinsztein DC, O’Donovan M, Owen M, Williams J, Abraham R. P1-327: Testing for association between Alzheimer’s disease with psychosis and functional gene candidates Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.705  0.371
2006 Proitsi P, Hamilton G, Archer N, Foy C, Hollinworth P, Owen M, Williams J, Lovestone S, Powell J. P1-326: Statistical and genetic studies on the psychosis sub-phenotype in Alzheimer’s disease Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.704  0.34
2006 Williams J, Harold D, Jehu L, Turic D, Hollingworth P, Moskvina V, Brayne C, Rubensztein D, Lovestone S, Powell J, Jones L, O'Donovan M, Owen M. P1-284: Interaction between ADAM12 and SH3MD1 may confer susceptibility to late-onset Alzheimer's disease Alzheimer's & Dementia. 2: S180-S180. DOI: 10.1016/J.Jalz.2006.05.661  0.416
2006 Jones L, Harold D, MacGregor S, Patterson CE, Hollingworth P, Owen MJ, Williams J, McIlroy S, Passmore P, O’Donovan M. P1-275: A single nucleotide polymorphism in CHAT influences response to acetylcholinesterase inhibitors in Alzheimer’s disease Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.652  0.313
2006 Li Y, Grupe A, Rowland C, Nowotny P, Kauwe JSK, Smemo S, Hinrichs A, Tacey K, Kwok S, Catanese J, Sninsky J, White TJ, Hollingworth P, Harris SL, Levine A, ... ... Owen M, et al. O2-02-07 Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.117  0.487
2006 Grupe A, Li Y, Rowland C, Abraham R, Hollingworth P, Morgan A, Jehu L, Stone D, Schadt E, Karnoub M, Nowotny P, Tacey K, Catanese J, Sninsky J, Rubinsztein D, ... ... Owen M, et al. O2-02-05: Novel candidate genes for late-onset Alzheimer's disease from a large scale association study of 20K functional variants Alzheimer's & Dementia. 2: S33-S33. DOI: 10.1016/J.Jalz.2006.05.115  0.53
2005 Thapar A, Langley K, Fowler T, Rice F, Turic D, Whittinger N, Aggleton J, Van den Bree M, Owen M, O'Donovan M. Catechol O-methyltransferase gene variant and birth weight predict early-onset antisocial behavior in children with attention-deficit/hyperactivity disorder. Archives of General Psychiatry. 62: 1275-8. PMID 16275815 DOI: 10.1001/Archpsyc.62.11.1275  0.351
2005 Thapar A, O'Donovan M, Owen MJ. The genetics of attention deficit hyperactivity disorder. Human Molecular Genetics. 14: R275-82. PMID 16244326 DOI: 10.1093/Hmg/Ddi263  0.37
2005 Hamshere ML, Bennett P, Williams N, Segurado R, Cardno A, Norton N, Lambert D, Williams H, Kirov G, Corvin A, Holmans P, Jones L, Jones I, Gill M, O'Donovan MC, ... Owen MJ, et al. Genomewide linkage scan in schizoaffective disorder: significant evidence for linkage at 1q42 close to DISC1, and suggestive evidence at 22q11 and 19p13. Archives of General Psychiatry. 62: 1081-8. PMID 16203953 DOI: 10.1001/Archpsyc.62.10.1081  0.423
2005 McGuffin P, Knight J, Breen G, Brewster S, Boyd PR, Craddock N, Gill M, Korszun A, Maier W, Middleton L, Mors O, Owen MJ, Perry J, Preisig M, Reich T, et al. Whole genome linkage scan of recurrent depressive disorder from the depression network study. Human Molecular Genetics. 14: 3337-45. PMID 16203746 DOI: 10.1093/Hmg/Ddi363  0.363
2005 Owen MJ. Genomic approaches to schizophrenia. Clinical Therapeutics. 27: S2-7. PMID 16198198 DOI: 10.1016/J.Clinthera.2005.07.014  0.432
2005 Williams NM, O'Donovan MC, Owen MJ. Is the dysbindin gene (DTNBP1) a susceptibility gene for schizophrenia? Schizophrenia Bulletin. 31: 800-5. PMID 16166606 DOI: 10.1093/Schbul/Sbi061  0.399
2005 Williams HJ, Glaser B, Williams NM, Norton N, Zammit S, MacGregor S, Kirov GK, Owen MJ, O'Donovan MC. No association between schizophrenia and polymorphisms in COMT in two large samples. The American Journal of Psychiatry. 162: 1736-8. PMID 16135635 DOI: 10.1176/Appi.Ajp.162.9.1736  0.387
2005 Norton N, Owen MJ. HTR2A: association and expression studies in neuropsychiatric genetics. Annals of Medicine. 37: 121-9. PMID 16026119 DOI: 10.1080/07853890510037347  0.391
2005 Owen MJ, Craddock N, O'Donovan MC. Schizophrenia: genes at last? Trends in Genetics : Tig. 21: 518-25. PMID 16009449 DOI: 10.1016/J.Tig.2005.06.011  0.417
2005 Glaser B, Schumacher J, Williams HJ, Jamra RA, Ianakiev N, Milev R, Ohlraun S, Schulze TG, Czerski PM, Hauser J, Jönsson EG, Sedvall GC, Klopp N, Illig T, Becker T, ... ... Owen MJ, et al. No association between the putative functional ZDHHC8 single nucleotide polymorphism rs175174 and schizophrenia in large European samples. Biological Psychiatry. 58: 78-80. PMID 15992527 DOI: 10.1016/J.Biopsych.2005.03.017  0.427
2005 Li Y, Rowland C, Tacey K, Catanese J, Sninsky J, Hardy J, Powell J, Lovestone S, Morris JC, Thal L, Goate A, Owen M, Williams J, Grupe A. The BDNF Val66Met polymorphism is not associated with late onset Alzheimer's disease in three case-control samples. Molecular Psychiatry. 10: 809-10. PMID 15970929 DOI: 10.1038/Sj.Mp.4001702  0.635
2005 Turic D, Langley K, Williams H, Norton N, Williams NM, Moskvina V, Van den Bree MB, Owen MJ, Thapar A, O'Donovan MC. A family based study implicates solute carrier family 1-member 3 (SLC1A3) gene in attention-deficit/hyperactivity disorder. Biological Psychiatry. 57: 1461-6. PMID 15950021 DOI: 10.1016/J.Biopsych.2005.03.025  0.374
2005 Lambert D, Middle F, Hamshere ML, Segurado R, Raybould R, Corvin A, Green E, O'Mahony E, Nikolov I, Mulcahy T, Haque S, Bort S, Bennett P, Norton N, Owen MJ, et al. Stage 2 of the Wellcome Trust UK-Irish bipolar affective disorder sibling-pair genome screen: evidence for linkage on chromosomes 6q16-q21, 4q12-q21, 9p21, 10p14-p12 and 18q22. Molecular Psychiatry. 10: 831-41. PMID 15940300 DOI: 10.1038/Sj.Mp.4001684  0.358
2005 Glaser B, Kirov G, Bray NJ, Green E, O'Donovan MC, Craddock N, Owen MJ. Identification of a potential bipolar risk haplotype in the gene encoding the winged-helix transcription factor RFX4. Molecular Psychiatry. 10: 920-7. PMID 15940297 DOI: 10.1038/Sj.Mp.4001689  0.432
2005 Kent L, Green E, Hawi Z, Kirley A, Dudbridge F, Lowe N, Raybould R, Langley K, Bray N, Fitzgerald M, Owen MJ, O'Donovan MC, Gill M, Thapar A, Craddock N. Association of the paternally transmitted copy of common Valine allele of the Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene with susceptibility to ADHD. Molecular Psychiatry. 10: 939-43. PMID 15940292 DOI: 10.1038/Sj.Mp.4001696  0.332
2005 Green EK, Raybould R, Macgregor S, Gordon-Smith K, Heron J, Hyde S, Grozeva D, Hamshere M, Williams N, Owen MJ, O'Donovan MC, Jones L, Jones I, Kirov G, Craddock N. Operation of the schizophrenia susceptibility gene, neuregulin 1, across traditional diagnostic boundaries to increase risk for bipolar disorder. Archives of General Psychiatry. 62: 642-8. PMID 15939841 DOI: 10.1001/Archpsyc.62.6.642  0.418
2005 Kirov G, O'Donovan MC, Owen MJ. Finding schizophrenia genes Journal of Clinical Investigation. 115: 1440-1448. PMID 15931379 DOI: 10.1172/Jci24759  0.439
2005 Bray NJ, Preece A, Williams NM, Moskvina V, Buckland PR, Owen MJ, O'Donovan MC. Haplotypes at the dystrobrevin binding protein 1 (DTNBP1) gene locus mediate risk for schizophrenia through reduced DTNBP1 expression. Human Molecular Genetics. 14: 1947-54. PMID 15917270 DOI: 10.1093/Hmg/Ddi199  0.408
2005 Norton N, Williams HJ, Dwyer S, Ivanov D, Preece AC, Gerrish A, Williams NM, Yerassimou P, Zammit S, O'Donovan MC, Owen MJ. No evidence for association between polymorphisms in GRM3 and schizophrenia. Bmc Psychiatry. 5: 23. PMID 15892884 DOI: 10.1186/1471-244X-5-23  0.392
2005 Craddock N, Owen MJ. The beginning of the end for the Kraepelinian dichotomy British Journal of Psychiatry. 186: 364-366. PMID 15863738 DOI: 10.1192/Bjp.186.5.364  0.341
2005 Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell T, Holmans P, Hamshere M, Turic D, Jehu L, Hollingworth P, Moore P, Bryden L, Myers A, Doil LM, Tacey KM, ... ... Owen MJ, et al. Association studies between risk for late-onset Alzheimer's disease and variants in insulin degrading enzyme. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 136: 62-8. PMID 15858813 DOI: 10.1002/Ajmg.B.30186  0.646
2005 Raybould R, Green EK, MacGregor S, Gordon-Smith K, Heron J, Hyde S, Caesar S, Nikolov I, Williams N, Jones L, O'Donovan MC, Owen MJ, Jones I, Kirov G, Craddock N. Bipolar disorder and polymorphisms in the dysbindin gene (DTNBP1). Biological Psychiatry. 57: 696-701. PMID 15820225 DOI: 10.1016/J.Biopsych.2005.01.018  0.438
2005 Craddock NJ, O'Donovan MC, Owen MJ. The genetics of schizophrenia and bipolar disorder: dissecting psychosis Journal of Medical Genetics. 42: 193-204. PMID 15744031 DOI: 10.1136/Jmg.2005.030718  0.42
2005 Holmans P, Hamshere M, Hollingworth P, Rice F, Tunstall N, Jones S, Moore P, Wavrant DeVrieze F, Myers A, Crook R, Compton D, Marshall H, Meyer D, Shears S, Booth J, ... ... Owen M, et al. Genome screen for loci influencing age at onset and rate of decline in late onset Alzheimer's disease. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 135: 24-32. PMID 15729734 DOI: 10.1002/Ajmg.B.30114  0.598
2005 Cope N, Harold D, Hill G, Moskvina V, Stevenson J, Holmans P, Owen MJ, O'Donovan MC, Williams J. Strong evidence that KIAA0319 on chromosome 6p is a susceptibility gene for developmental dyslexia. American Journal of Human Genetics. 76: 581-91. PMID 15717286 DOI: 10.1086/429131  0.396
2005 Li Y, Hollingworth P, Moore P, Foy C, Archer N, Powell J, Nowotny P, Holmans P, O'Donovan M, Tacey K, Doil L, van Luchene R, Garcia V, Rowland C, Lau K, ... ... Owen M, et al. Genetic association of the APP binding protein 2 gene (APBB2) with late onset Alzheimer disease. Human Mutation. 25: 270-7. PMID 15714520 DOI: 10.1002/Humu.20138  0.649
2005 Owen MJ, O'Donovan MC, Harrison PJ. Schizophrenia: a genetic disorder of the synapse? Bmj (Clinical Research Ed.). 330: 158-9. PMID 15661762 DOI: 10.1136/Bmj.330.7484.158  0.351
2005 Turic D, Williams H, Langley K, Owen M, Thapar A, O'Donovan MC. A family based study of catechol-O-methyltransferase (COMT) and attention deficit hyperactivity disorder (ADHD). American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 133: 64-7. PMID 15635644 DOI: 10.1002/Ajmg.B.30123  0.34
2005 Green E, Elvidge G, Jacobsen N, Glaser B, Jones IR, O'Donovan MC, Kirov G, Owen MJ, Craddock NJ. Localization of bipolar susceptibility locus by molecular genetic analysis of the chromosome 12q23-q24 region in two pedigrees with bipolar disorder and Darier's disease. American Journal of Psychiatry. 162: 35-42. PMID 15625199 DOI: 10.1176/Appi.Ajp.162.1.35  0.391
2005 Dimitrova A, Milanova V, Krastev S, Nikolov I, Toncheva D, Owen MJ, Kirov G. Association study of myo-inositol monophosphatase 2 (IMPA2) polymorphisms with bipolar affective disorder and response to lithium treatment. Pharmacogenomics Journal. 5: 35-41. PMID 15505643 DOI: 10.1038/Sj.Tpj.6500273  0.373
2005 Glaser B, Kirov G, Green E, Craddock NJ, Owen MJ. Linkage disequilibrium mapping of bipolar affective disorder at 12q23-q24 provides evidence for association at CUX2 and FLJ32356 American Journal of Medical Genetics. 132: 38-45. PMID 15389760 DOI: 10.1002/Ajmg.B.30081  0.407
2005 Morris DW, Ivanov D, Robinson L, Williams N, Stevenson J, Owen MJ, Williams J, O'Donovan MC. Association analysis of two candidate phospholipase genes that map to the chromosome 15q15.1-15.3 region associated with reading disability. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 97-103. PMID 15274049 DOI: 10.1002/Ajmg.B.30033  0.415
2004 van Amelsvoort T, Daly E, Henry J, Robertson D, Ng V, Owen M, Murphy KC, Murphy DG. Brain anatomy in adults with velocardiofacial syndrome with and without schizophrenia: preliminary results of a structural magnetic resonance imaging study. Archives of General Psychiatry. 61: 1085-96. PMID 15520356 DOI: 10.1001/Archpsyc.61.11.1085  0.345
2004 Li Y, Nowotny P, Holmans P, Smemo S, Kauwe JS, Hinrichs AL, Tacey K, Doil L, van Luchene R, Garcia V, Rowland C, Schrodi S, Leong D, Gogic G, Chan J, ... ... Owen M, et al. Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family. Proceedings of the National Academy of Sciences of the United States of America. 101: 15688-93. PMID 15507493 DOI: 10.1073/Pnas.0403535101  0.676
2004 Bray NJ, Jehu L, Moskvina V, Buxbaum JD, Dracheva S, Haroutunian V, Williams J, Buckland PR, Owen MJ, O'Donovan MC. Allelic expression of APOE in human brain: effects of epsilon status and promoter haplotypes. Human Molecular Genetics. 13: 2885-92. PMID 15385439 DOI: 10.1093/Hmg/Ddh299  0.349
2004 Amelsvoort Tv, Henry J, Morris R, Owen M, Linszen D, Murphy K, Murphy D. Cognitive deficits associated with schizophrenia in velo-cardio-facial syndrome Schizophrenia Research. 70: 223-232. PMID 15329299 DOI: 10.1016/J.Schres.2003.10.004  0.375
2004 Farbrother JE, Kirov G, Owen MJ, Pong-Wong R, Haley CS, Guggenheim JA. Linkage analysis of the genetic loci for high myopia on 18p, 12q, and 17q in 51 U.K. families. Investigative Ophthalmology & Visual Science. 45: 2879-85. PMID 15326098 DOI: 10.1167/Iovs.03-1156  0.317
2004 Li Y, Tacey K, Doil L, van Luchene R, Garcia V, Rowland C, Schrodi S, Leong D, Lau K, Catanese J, Sninsky J, Nowotny P, Holmans P, Hardy J, Powell J, ... ... Owen M, et al. Association of ABCA1 with late-onset Alzheimer's disease is not observed in a case-control study. Neuroscience Letters. 366: 268-71. PMID 15288432 DOI: 10.1016/J.Neulet.2004.05.047  0.637
2004 Cichon S, Buervenich S, Kirov G, Akula N, Dimitrova A, Green E, Schumacher J, Klopp N, Becker T, Ohlraun S, Schulze TG, Tullius M, Gross MM, Jones L, Krastev S, ... ... Owen MJ, et al. Lack of support for a genetic association of the XBP1 promoter polymorphism with bipolar disorder in probands of European origin. Nature Genetics. 36: 783-4; author reply . PMID 15284840 DOI: 10.1038/Ng0804-783  0.392
2004 Zammit S, Jones G, Jones SJ, Norton N, Sanders RD, Milham C, McCarthy GM, Jones LA, Cardno AG, Gray M, Murphy KC, O'Donovan MC, Owen MJ. Polymorphisms in the MAOA, MAOB, and COMT genes and aggressive behavior in schizophrenia. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 128: 19-20. PMID 15211623 DOI: 10.1002/Ajmg.B.30021  0.398
2004 Reid SJ, van Roon-Mom WM, Wood PC, Rees MI, Owen MJ, Faull RL, Dragunow M, Snell RG. TBP, a polyglutamine tract containing protein, accumulates in Alzheimer's disease. Brain Research. Molecular Brain Research. 125: 120-8. PMID 15193429 DOI: 10.1016/J.Molbrainres.2004.03.018  0.343
2004 Mills S, Langley K, Van den Bree M, Street E, Turic D, Owen MJ, O'Donovan MC, Thapar A. No evidence of association between Catechol-O-Methyltransferase (COMT) Val158Met genotype and performance on neuropsychological tasks in children with ADHD: a case-control study. Bmc Psychiatry. 4: 15. PMID 15182372 DOI: 10.1186/1471-244X-4-15  0.312
2004 Williams NM, Owen MJ. Genetic abnormalities of chromosome 22 and the development of psychosis Current Psychiatry Reports. 6: 176-182. PMID 15142470 DOI: 10.1007/S11920-004-0062-4  0.414
2004 Owen MJ, Williams NM, O'Donovan MC. Dysbindin-1 and chnizophrenia: From genetics to neuropathology Journal of Clinical Investigation. 113: 1255-1257. PMID 15124015 DOI: 10.1172/Jci21470  0.353
2004 Kirov G, Ivanov D, Williams NM, Preece A, Nikolov I, Milev R, Koleva S, Dimitrova A, Toncheva D, O'Donovan MC, Owen MJ. Strong evidence for association between the dystrobrevin binding protein 1 gene (DTNBP1) and schizophrenia in 488 parent-offspring trios from Bulgaria. Biological Psychiatry. 55: 971-5. PMID 15121479 DOI: 10.1016/J.Biopsych.2004.01.025  0.428
2004 Busby V, Goossens S, Nowotny P, Hamilton G, Smemo S, Harold D, Turic D, Jehu L, Myers A, Womick M, Woo D, Compton D, Doil LM, Tacey KM, Lau KF, ... ... Owen MJ, et al. Alpha-T-catenin is expressed in human brain and interacts with the Wnt signaling pathway but is not responsible for linkage to chromosome 10 in Alzheimer's disease. Neuromolecular Medicine. 5: 133-46. PMID 15075440 DOI: 10.1385/Nmm:5:2:133  0.631
2004 Cook LJ, Ho LW, Taylor AE, Brayne C, Evans JG, Xuereb J, Cairns NJ, Pritchard A, Lemmon H, Mann D, St Clair D, Turic D, Hollingworth P, Moore PJ, Jehu L, ... ... Owen MJ, et al. Candidate gene association studies of the alpha 4 (CHRNA4) and beta 2 (CHRNB2) neuronal nicotinic acetylcholine receptor subunit genes in Alzheimer's disease. Neuroscience Letters. 358: 142-6. PMID 15026168 DOI: 10.1016/J.Neulet.2004.01.016  0.369
2004 Mowry BJ, Holmans PA, Pulver AE, Gejman PV, Riley B, Williams NM, Laurent C, Schwab SG, Wildenauer DB, Bauché S, Owen MJ, Wormley B, Sanders AR, Nestadt G, Liang KY, et al. Multicenter linkage study of schizophrenia loci on chromosome 22q. Molecular Psychiatry. 9: 784-95. PMID 15007391 DOI: 10.1038/Sj.Mp.4001481  0.398
2004 Plomin R, Turic DM, Hill L, Turic DE, Stephens M, Williams J, Owen MJ, O'Donovan MC. A functional polymorphism in the succinate-semialdehyde dehydrogenase (aldehyde dehydrogenase 5 family, member A1) gene is associated with cognitive ability. Molecular Psychiatry. 9: 582-6. PMID 14981524 DOI: 10.1038/Sj.Mp.4001441  0.343
2004 Turic D, Langley K, Mills S, Stephens M, Lawson D, Govan C, Williams N, Van Den Bree M, Craddock N, Kent L, Owen M, O'Donovan M, Thapar A. Follow-up of genetic linkage findings on chromosome 16p13: evidence of association of N-methyl-D aspartate glutamate receptor 2A gene polymorphism with ADHD. Molecular Psychiatry. 9: 169-73. PMID 14966475 DOI: 10.1038/Sj.Mp.4001387  0.372
2004 Williams NM, Preece A, Spurlock G, Norton N, Williams HJ, McCreadie RG, Buckland P, Sharkey V, Chowdari KV, Zammit S, Nimgaonkar V, Kirov G, Owen MJ, O'Donovan MC. Support for RGS4 as a susceptibility gene for schizophrenia. Biological Psychiatry. 55: 192-5. PMID 14732600 DOI: 10.1016/J.Biopsych.2003.11.002  0.408
2004 Langley K, Marshall L, van den Bree M, Thomas H, Owen M, O'Donovan M, Thapar A. Association of the dopamine D4 receptor gene 7-repeat allele with neuropsychological test performance of children with ADHD. The American Journal of Psychiatry. 161: 133-8. PMID 14702261 DOI: 10.1176/Appi.Ajp.161.1.133  0.3
2004 Bray NJ, Buckland PR, Hall H, Owen MJ, O'Donovan MC. The serotonin-2A receptor gene locus does not contain common polymorphism affecting mRNA levels in adult brain. Molecular Psychiatry. 9: 109-14. PMID 14699448 DOI: 10.1038/Sj.Mp.4001366  0.372
2004 Myers AJ, Marshall H, Holmans P, Compton D, Crook RJ, Mander AP, Nowotny P, Smemo S, Dunstan M, Jehu L, Wang JC, Hamshere M, Morris JC, Norton J, Chakraventy S, ... ... Owen MJ, et al. Variation in the urokinase-plasminogen activator gene does not explain the chromosome 10 linkage signal for late onset AD. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 124: 29-37. PMID 14681909 DOI: 10.1002/Ajmg.B.20036  0.617
2004 Owen MJ, Williams NM, O'Donovan MC. The molecular genetics of schizophrenia: New findings promise new insights Molecular Psychiatry. 9: 14-27. PMID 14581932 DOI: 10.1038/Sj.Mp.4001444  0.413
2004 Jones G, Owen MJ. Genetics: The implications for forensic psychiatry Journal of Forensic Psychiatry & Psychology. 15: 696-704. DOI: 10.1080/14789940410001729509  0.4
2004 Li Y, Hollingworth P, Moore P, Foy C, Archer N, Nowotny P, Holmans P, Smemo S, Tacey K, Doil L, Luchene Rv, Lau K, Catanese J, Garcia V, Rowland C, ... ... Owen M, et al. P4-122 Genetic association of an APP binding protein gene with late onset Alzheimer's disease Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81680-4  0.633
2004 Doil L, Tacey K, Nowotny P, Luchene Rv, Li Y, Holmans P, Smemo S, Garcia V, Rowland C, Leong D, Gogic G, Cravchik A, Ross D, Lau K, Catanese J, ... ... Owen M, et al. P4-110 A systematic scan of chromosome 10 single nucleotide polymorphisms identifies novel candidate genes showing strong association to Alzheimer's disease Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81668-3  0.655
2004 Lau KF, Rowland C, Tacey K, Doil L, Li Y, Luchene Rv, Nowotny P, Smemo S, Garcia V, Lovestone S, Owen M, Williams J, Grupe A, Goate A. P4-067 Genetic association studies of insulin-degrading enzyme (IDE) with late onset Alzheimer's disease (LOAD) - Equivocal results from two large case-control studies Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81625-7  0.544
2004 Busby VL, Hamilton G, Walter S, Foy C, Archer N, Turic D, Jehu L, Hollingworth P, Moore P, Jones S, Jones L, Williams J, Owen M, Powell J, Lovestone S. P4-059 CDC2 as a candidate for late-onset Alzheimer's disease Neurobiology of Aging. 25: S490. DOI: 10.1016/S0197-4580(04)81617-8  0.332
2004 Hamilton G, Samadi F, Archer N, Foy C, Walter S, Turic D, Jehu L, Hollingworth P, Jones S, Moore P, Jones L, Williams J, Owen M, Lovestone S, Powell J. P4-058 Searching chromosome 10 for an AD risk factor — Analysis of a positional and biological candidate Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81616-6  0.311
2004 Li Y, Nowotny P, Holmans P, Smemo S, Kawe K, Tacey K, Doil L, Luchene Rv, Garcia V, Rowland C, Schrodi S, Leong D, Chan J, Lau K, Chang S, ... ... Owen M, et al. P4-046 Association of late onset Alzheimer's disease with genetic variation in multiple members of a gene family involved in neuronal apoptosis Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81604-X  0.619
2004 Hollingworth P, Hamshere ML, Hill GT, Moore PJ, Ludford RM, Foy C, Archer N, Edmondson A, Proitsi P, Lynch A, Evans I, Hamilton B, Lovestone S, Powell J, Brayne C, ... ... Owen MJ, et al. P1-014 Principal components analysis of the neuropsychiatric inventory in Alzheimer's disease Neurobiology of Aging. 25: S97. DOI: 10.1016/S0197-4580(04)80328-2  0.307
2003 Heron J, Jones I, Williams J, Owen MJ, Craddock N, Jones LA. Self-reported schizotypy and bipolar disorder: demonstration of a lack of specificity of the Kings Schizotypy Questionnaire. Schizophrenia Research. 65: 153-8. PMID 14630308 DOI: 10.1016/S0920-9964(03)00004-5  0.357
2003 Williams NM, Norton N, Williams H, Ekholm B, Hamshere ML, Lindblom Y, Chowdari KV, Cardno AG, Zammit S, Jones LA, Murphy KC, Sanders RD, McCarthy G, Gray MY, Jones G, ... ... Owen MJ, et al. A systematic genomewide linkage study in 353 sib pairs with schizophrenia. American Journal of Human Genetics. 73: 1355-67. PMID 14628288 DOI: 10.1086/380206  0.367
2003 Marchbanks RM, Ryan M, Day INM, Owen MJ, McGuffin P, Whatley SA. A mitochondrial DNA sequence variant associated with schizophrenia and oxidative stress. Schizophrenia Research. 65: 33-38. PMID 14623372 DOI: 10.1016/S0920-9964(03)00011-2  0.356
2003 Ivanov DK, Kirov G, Norton N, Williams HJ, Williams NM, Nikolov I, Tzwetkova R, Stambolova SM, Murphy KC, Toncheva D, Thapar A, O'Donovan MC, Owen MJ. Chromosome 22q11 deletions, velo-cardio-facial syndrome and early-onset psychosis. Molecular genetic study. British Journal of Psychiatry. 183: 409-413. PMID 14594915 DOI: 10.1192/Bjp.183.5.409  0.37
2003 Zammit S, Allebeck P, Dalman C, Lundberg I, Hemmingson T, Owen MJ, Lewis G. Paternal age and risk for schizophrenia British Journal of Psychiatry. 183: 405-408. PMID 14594914 DOI: 10.1192/Bjp.183.5.405  0.356
2003 Kirov G, Georgieva L, Williams N, Nikolov I, Norton N, Toncheva D, O'Donovan M, Owen MJ. Variation in the protocadherin gamma A gene cluster. Genomics. 82: 433-40. PMID 13679023 DOI: 10.1016/S0888-7543(03)00167-8  0.4
2003 Payton A, Turic D, Langley K, Mills S, Lawson DC, Van den Bree M, Owen MJ, O'Donovan MC, Ollier W, Worthington J, Thapar A. No evidence of association between HLA-DRB1 and attention deficit hyperactivity disorder. Psychiatric Genetics. 13: 183-5. PMID 12960752 DOI: 10.1097/00041444-200309000-00009  0.309
2003 O'Donovan MC, Williams NM, Owen MJ. Recent advances in the genetics of schizophrenia Human Molecular Genetics. 12. PMID 12952866 DOI: 10.1093/Hmg/Ddg302  0.415
2003 Williams HJ, Williams N, Spurlock G, Norton N, Ivanov D, McCreadie RG, Preece A, Sharkey V, Jones S, Zammit S, Nikolov I, Kehaiov I, Thapar A, Murphy KC, Kirov G, ... Owen MJ, et al. Association between PRODH and schizophrenia is not confirmed. Molecular Psychiatry. 8: 644-5. PMID 12874599 DOI: 10.1038/Sj.Mp.4001276  0.346
2003 Williams HJ, Williams NM, Spurlock G, Norton N, Zammit S, Kirov G, Owen MJ, O'Donovan MC. Detailed analysis of PRODH and PsPRODH reveals no association with schizophrenia. American Journal of Medical Genetics. 120: 42-46. PMID 12815738 DOI: 10.1002/Ajmg.B.20049  0.442
2003 Norton N, Williams HJ, Williams NM, Spurlock G, Zammit S, Jones G, Jones S, Owen R, O'Donovan MC, Owen MJ. Mutation screening of the Homer gene family and association analysis in schizophrenia American Journal of Medical Genetics - Neuropsychiatric Genetics. 120: 18-21. PMID 12815733 DOI: 10.1002/Ajmg.B.20032  0.431
2003 Williams NM, Preece A, Spurlock G, Norton N, Williams HJ, Zammit S, O'Donovan MC, Owen MJ. Support for genetic variation in neuregulin 1 and susceptibility to schizophrenia. Molecular Psychiatry. 8: 485-7. PMID 12808428 DOI: 10.1038/Sj.Mp.4001348  0.417
2003 Lewis CM, Levinson DF, Wise LH, DeLisi LE, Straub RE, Hovatta I, Williams NM, Schwab SG, Pulver AE, Faraone SV, Brzustowicz LM, Kaufmann CA, Garver DL, Gurling HM, Lindholm E, ... ... Owen MJ, et al. Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia. American Journal of Human Genetics. 73: 34-48. PMID 12802786 DOI: 10.1086/376549  0.382
2003 Bray NJ, Buckland PR, Williams NM, Williams HJ, Norton N, Owen MJ, O'Donovan MC. A haplotype implicated in schizophrenia susceptibility is associated with reduced COMT expression in human brain. American Journal of Human Genetics. 73: 152-61. PMID 12802784 DOI: 10.1086/376578  0.404
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