| Year |
Citation |
Score |
| 2020 |
McCamphill PK, Stoppel LJ, Senter RK, Lewis MC, Heynen AJ, Stoppel DC, Sridhar V, Collins KA, Shi X, Pan JQ, Madison J, Cottrell JR, Huber KM, Scolnick EM, Holson EB, ... Wagner FF, et al. Selective inhibition of glycogen synthase kinase 3α corrects pathophysiology in a mouse model of fragile X syndrome. Science Translational Medicine. 12. PMID 32434848 DOI: 10.1126/Scitranslmed.Aam8572 |
0.316 |
|
| 2017 |
Strebl MG, Campbell AJ, Zhao WN, Schroeder FA, Riley MM, Chindavong PS, Morin TM, Haggarty SJ, Wagner FF, Ritter T, Hooker JM. HDAC6 Brain Mapping with [(18)F]Bavarostat Enabled by a Ru-Mediated Deoxyfluorination. Acs Central Science. 3: 1006-1014. PMID 28979942 DOI: 10.1021/Acscentsci.7B00274 |
0.332 |
|
| 2017 |
Schuetze KB, Stratton MS, Blakeslee WW, Wempe MF, Wagner FF, Holson EB, Kuo YM, Andrews AJ, Gilbert TM, Hooker JM, McKinsey TA. Overlapping and Divergent Actions of Structurally Distinct HDAC Inhibitors in Cardiac Fibroblasts. The Journal of Pharmacology and Experimental Therapeutics. PMID 28174211 DOI: 10.1124/Jpet.116.237701 |
0.328 |
|
| 2016 |
Wagner FF, Weïwer M, Steinbacher S, Schomburg A, Reinemer P, Gale JP, Campbell AJ, Fisher SL, Zhao WN, Reis SA, Hennig KM, Thomas M, Müller P, Jefson MR, Fass DM, et al. Kinetic and structural insights into the binding of histone deacetylase 1 and 2 (HDAC1, 2) inhibitors. Bioorganic & Medicinal Chemistry. PMID 27377864 DOI: 10.1016/J.Bmc.2016.06.040 |
0.332 |
|
| 2016 |
Wagner FF, Bishop JA, Gale JP, Shi X, Walk M, Ketterman J, Patnaik D, Barker D, Walpita D, Campbell AJ, Nguyen S, Lewis M, Ross L, Weiwer M, An WF, et al. Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-wide Selectivity and their Functional Effects. Acs Chemical Biology. PMID 27128528 DOI: 10.1021/Acschembio.6B00306 |
0.305 |
|
| 2015 |
Wagner FF, Lundh M, Kaya T, McCarren P, Zhang YL, Chattopadhyay S, Gale JP, Galbo T, Fisher SL, Meier BC, Vetere A, Richardson S, Morgan NG, Christensen DP, Gilbert TJ, et al. An Isochemogenic Set of Inhibitors To Define the Therapeutic Potential of Histone Deacetylases in β-Cell Protection. Acs Chemical Biology. PMID 26640968 DOI: 10.1021/Acschembio.5B00640 |
0.34 |
|
| 2015 |
Olson DE, Sleiman SF, Bourassa MW, Wagner FF, Gale JP, Zhang YL, Ratan RR, Holson EB. Hydroxamate-based histone deacetylase inhibitors can protect neurons from oxidative stress via a histone deacetylase-independent catalase-like mechanism. Chemistry & Biology. 22: 439-45. PMID 25892200 DOI: 10.1016/J.Chembiol.2015.03.014 |
0.323 |
|
| 2015 |
Wagner FF, Zhang YL, Fass DM, Joseph N, Gale JP, Weïwer M, McCarren P, Fisher SL, Kaya T, Zhao WN, Reis SA, Hennig KM, Thomas M, Lemercier BC, Lewis MC, et al. Kinetically Selective Inhibitors of Histone Deacetylase 2 (HDAC2) as Cognition Enhancers. Chemical Science (Royal Society of Chemistry : 2010). 6: 804-815. PMID 25642316 DOI: 10.1039/C4Sc02130D |
0.33 |
|
| 2015 |
Benajiba L, Wagner F, Ross L, Galinsky I, DeAngelo DJ, Gale J, Pan J, Zhang Y, Sacher J, Weiwer M, Stone RM, Holson E, Stegmaier K. Identification of a First in Class GSK3-Alpha Selective Inhibitor As a New Differentiation Therapy for AML Blood. 126: 870-870. DOI: 10.1182/Blood.V126.23.870.870 |
0.307 |
|
| 2014 |
Sleiman SF, Olson DE, Bourassa MW, Karuppagounder SS, Zhang YL, Gale J, Wagner FF, Basso M, Coppola G, Pinto JT, Holson EB, Ratan RR. Hydroxamic acid-based histone deacetylase (HDAC) inhibitors can mediate neuroprotection independent of HDAC inhibition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 14328-37. PMID 25339746 DOI: 10.1523/Jneurosci.1010-14.2014 |
0.343 |
|
| 2014 |
Wang C, Schroeder FA, Wey HY, Borra R, Wagner FF, Reis S, Kim SW, Holson EB, Haggarty SJ, Hooker JM. In vivo imaging of histone deacetylases (HDACs) in the central nervous system and major peripheral organs. Journal of Medicinal Chemistry. 57: 7999-8009. PMID 25203558 DOI: 10.1021/Jm500872P |
0.306 |
|
| 2014 |
Olson DE, Udeshi ND, Wolfson NA, Pitcairn CA, Sullivan ED, Jaffe JD, Svinkina T, Natoli T, Lu X, Paulk J, McCarren P, Wagner FF, Barker D, Howe E, Lazzaro F, et al. An unbiased approach to identify endogenous substrates of "histone" deacetylase 8. Acs Chemical Biology. 9: 2210-6. PMID 25089360 DOI: 10.1021/Cb500492R |
0.304 |
|
| 2014 |
Cash BM, Prevost N, Wagner FF, Comins DL. Studies toward the total synthesis of dihydrolycolucine. Preparation of AB and CEF ring fragments. The Journal of Organic Chemistry. 79: 5740-5. PMID 24841361 DOI: 10.1021/Jo500878V |
0.612 |
|
| 2014 |
Seo YJ, Kang Y, Muench L, Reid A, Caesar S, Jean L, Wagner F, Holson E, Haggarty SJ, Weiss P, King P, Carter P, Volkow ND, Fowler JS, Hooker JM, et al. Image-guided synthesis reveals potent blood-brain barrier permeable histone deacetylase inhibitors. Acs Chemical Neuroscience. 5: 588-96. PMID 24780082 DOI: 10.1021/Cn500021P |
0.346 |
|
| 2013 |
Wagner FF, WeÑ—wer M, Lewis MC, Holson EB. Small molecule inhibitors of zinc-dependent histone deacetylases. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 10: 589-604. PMID 24101253 DOI: 10.1007/S13311-013-0226-1 |
0.339 |
|
| 2013 |
Schroeder FA, Lewis MC, Fass DM, Wagner FF, Zhang YL, Hennig KM, Gale J, Zhao WN, Reis S, Barker DD, Berry-Scott E, Kim SW, Clore EL, Hooker JM, Holson EB, et al. A selective HDAC 1/2 inhibitor modulates chromatin and gene expression in brain and alters mouse behavior in two mood-related tests. Plos One. 8: e71323. PMID 23967191 DOI: 10.1371/Journal.Pone.0071323 |
0.331 |
|
| 2013 |
Olson DE, Wagner FF, Kaya T, Gale JP, Aidoud N, Davoine EL, Lazzaro F, Weïwer M, Zhang YL, Holson EB. Discovery of the first histone deacetylase 6/8 dual inhibitors. Journal of Medicinal Chemistry. 56: 4816-20. PMID 23672185 DOI: 10.1021/Jm400390R |
0.341 |
|
| 2013 |
Wagner FF, Olson DE, Gale JP, Kaya T, Weïwer M, Aidoud N, Thomas M, Davoine EL, Lemercier BC, Zhang YL, Holson EB. Potent and selective inhibition of histone deacetylase 6 (HDAC6) does not require a surface-binding motif. Journal of Medicinal Chemistry. 56: 1772-6. PMID 23368884 DOI: 10.1021/Jm301355J |
0.324 |
|
| 2012 |
Lowe JT, Lee MD, Akella LB, Davoine E, Donckele EJ, Durak L, Duvall JR, Gerard B, Holson EB, Joliton A, Kesavan S, Lemercier BC, Liu H, Marié JC, Mulrooney CA, ... ... Wagner FF, et al. Synthesis and profiling of a diverse collection of azetidine-based scaffolds for the development of CNS-focused lead-like libraries. The Journal of Organic Chemistry. 77: 7187-211. PMID 22853001 DOI: 10.1021/Jo300974J |
0.388 |
|
| 2012 |
Kubicek S, Gilbert JC, Fomina-Yadlin D, Gitlin AD, Yuan Y, Wagner FF, Holson EB, Luo T, Lewis TA, Taylor B, Gupta S, Shamji AF, Wagner BK, Clemons PA, Schreiber SL. Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 5364-9. PMID 22434908 DOI: 10.1073/Pnas.1201079109 |
0.323 |
|
| 2007 |
Wagner FF, Comins DL. Recent advances in the synthesis of nicotine and its derivatives Tetrahedron. 63: 8065-8082. DOI: 10.1016/J.Tet.2007.04.100 |
0.529 |
|
| 2006 |
Wagner FF, Comins DL. Expedient five-step synthesis of SIB-1508Y from natural nicotine. The Journal of Organic Chemistry. 71: 8673-5. PMID 17064057 DOI: 10.1021/Jo0616052 |
0.562 |
|
| 2006 |
Wagner FF, Comins DL. Six-step synthesis of (S)-brevicolline from (S)-nicotine. Organic Letters. 8: 3549-52. PMID 16869657 DOI: 10.1021/Ol061334H |
0.566 |
|
| 2006 |
Comins D, Wagner F. Synthesis of (S)-Brevicolline Synfacts. 2006: 1198-1198. DOI: 10.1055/S-2006-955590 |
0.543 |
|
| 2006 |
Wagner FF, Comins DL. Regioselective 5-, 4-, and 2-substitution of (S)-6-chloronicotine and 4-substitution of (S)-5-chloronicotine European Journal of Organic Chemistry. 3562-3565. DOI: 10.1002/Ejoc.200600415 |
0.548 |
|
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