Kavi Devraj, Ph.D. - Publications

Affiliations: 
2010 Pennsylvania State University, State College, PA, United States 
Area:
Neuroscience Biology, Neurobiology Biology, Biomedical Engineering, Biochemistry

28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Schumacher L, Slimani R, Zizmare L, Ehlers J, Kleine Borgmann F, Fitzgerald JC, Fallier-Becker P, Beckmann A, Grißmer A, Meier C, El-Ayoubi A, Devraj K, Mittelbronn M, Trautwein C, Naumann U. TGF-Beta Modulates the Integrity of the Blood Brain Barrier In Vitro, and Is Associated with Metabolic Alterations in Pericytes. Biomedicines. 11. PMID 36672722 DOI: 10.3390/biomedicines11010214  0.33
2022 Fouani Y, Kirchhof L, Stanicek L, Luxán G, Heumüller AW, Knau A, Fischer A, Devraj K, John D, Neumann P, Bindereif A, Boon RA, Liebner S, Wittig I, Mogler C, et al. The splicing-regulatory lncRNA NTRAS sustains vascular integrity. Embo Reports. e54157. PMID 35527520 DOI: 10.15252/embr.202154157  0.311
2021 Hansen L, Lohfink N, Vutukuri R, Kestner RI, Trautmann S, Hecht M, Wagner PV, Spitzer D, Khel MI, Macas J, Ferreirós N, Gurke R, Günther S, Pfeilschifter W, Devraj K. Endothelial sphingosine-1-phosphate receptor 4 regulates blood-brain barrier permeability and promotes a homeostatic endothelial phenotype. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 34903569 DOI: 10.1523/JNEUROSCI.0188-21.2021  0.336
2020 Guérit S, Fidan E, Macas J, Czupalla CJ, Figueiredo R, Vijikumar A, Yalcin BH, Thom S, Winter P, Gerhardt H, Devraj K, Liebner S. Astrocyte-derived Wnt growth factors are required for endothelial blood-brain barrier maintenance. Progress in Neurobiology. 101937. PMID 33383106 DOI: 10.1016/j.pneurobio.2020.101937  0.377
2020 Devraj G, Guérit S, Seele J, Spitzer D, Macas J, Khel MI, Heidemann R, Braczynski AK, Ballhorn W, Günther S, Ogunshola OO, Mittelbronn M, Ködel U, Monoranu CM, Plate KH, ... ... Devraj K, et al. HIF-1α is involved in blood-brain barrier dysfunction and paracellular migration of bacteria in pneumococcal meningitis. Acta Neuropathologica. PMID 32529267 DOI: 10.1007/S00401-020-02174-2  0.45
2020 Kestner RI, Mayser F, Vutukuri R, Hansen L, Günther S, Brunkhorst R, Devraj K, Pfeilschifter W. Gene Expression Dynamics at the Neurovascular Unit During Early Regeneration After Cerebral Ischemia/Reperfusion Injury in Mice. Frontiers in Neuroscience. 14: 280. PMID 32300291 DOI: 10.3389/Fnins.2020.00280  0.324
2020 Winkler L, Blasig R, Breitkreuz-Korff O, Berndt P, Dithmer S, Helms HC, Puchkov D, Devraj K, Kaya M, Qin Z, Liebner S, Wolburg H, Andjelkovic AV, Rex A, Blasig IE, et al. Tight junctions in the blood-brain barrier promote edema formation and infarct size in stroke - Ambivalent effects of sealing proteins. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X20904687. PMID 32054373 DOI: 10.1177/0271678X20904687  0.35
2019 Bernatz S, Ilina EI, Devraj K, Harter PN, Mueller K, Kleber S, Braun Y, Penski C, Renner C, Halder R, Jennewein L, Solbach C, Thorsen F, Pestalozzi BC, Mischo A, et al. Impact of Docetaxel on blood-brain barrier function and formation of breast cancer brain metastases. Journal of Experimental & Clinical Cancer Research : Cr. 38: 434. PMID 31665089 DOI: 10.1186/S13046-019-1427-1  0.341
2019 Di Tacchio M, Macas J, Weissenberger J, Sommer K, Bähr O, Steinbach JP, Senft C, Seifert V, Glas M, Herrlinger U, Krex D, Meinhardt M, Weyerbrock A, Timmer M, Goldbrunner R, ... ... Devraj K, et al. Tumor vessel normalization, immuno-stimulatory reprogramming, and improved survival in glioblastoma with combined inhibition of PD-1, angiopoietin-2, and VEGF. Cancer Immunology Research. PMID 31597643 DOI: 10.1158/2326-6066.Cir-18-0865  0.347
2019 Dubinski D, Hattingen E, Senft C, Seifert V, Peters KG, Reiss Y, Devraj K, Plate KH. Controversial roles for dexamethasone in glioblastoma - Opportunities for novel vascular targeting therapies. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X19859847. PMID 31238763 DOI: 10.1177/0271678X19859847  0.368
2018 Devraj K, Guérit S, Macas J, Reiss Y. An In Vivo Blood-brain Barrier Permeability Assay in Mice Using Fluorescently Labeled Tracers. Journal of Visualized Experiments : Jove. PMID 29553506 DOI: 10.3791/57038  0.419
2017 Hu J, Dziumbla S, Lin J, Bibli SI, Zukunft S, de Mos J, Awwad K, Frömel T, Jungmann A, Devraj K, Cheng Z, Wang L, Fauser S, Eberhart CG, Sodhi A, et al. Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy. Nature. 552: 248-252. PMID 29211719 DOI: 10.1038/Nature25013  0.341
2017 Vutukuri R, Brunkhorst R, Kestner RI, Hansen L, Ferreiros Bouzas N, Pfeilschifter J, Devraj K, Pfeilschifter W. Alteration of sphingolipid metabolism as a putative mechanism underlying LPS-induced BBB disruption. Journal of Neurochemistry. PMID 29023711 DOI: 10.1111/Jnc.14236  0.389
2017 Leisegang MS, Fork C, Josipovic I, Richter F, Preussner J, Hu J, Miller MJ, Epah JN, Hofmann P, Günther S, Moll F, Valasarajan C, Heidler J, Ponomareva Y, Freiman TM, ... ... Devraj K, et al. Long Noncoding RNA MANTIS Facilitates Endothelial Angiogenic Function. Circulation. PMID 28351900 DOI: 10.1161/Circulationaha.116.026991  0.336
2016 Gross S, Devraj K, Feng Y, Macas J, Liebner S, Wieland T. Nucleoside diphosphate kinase B regulates angiogenic responses in the endothelium via caveolae formation and c-Src-mediated caveolin-1 phosphorylation. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 27629102 DOI: 10.1177/0271678X16669365  0.352
2016 Ziegler N, Awwad K, Fisslthaler B, Reis M, Devraj K, Corada M, Minardi SP, Dejana E, Plate KH, Fleming I, Liebner S. β-Catenin Is Required for Endothelial Cyp1b1 Regulation Influencing Metabolic Barrier Function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 8921-35. PMID 27559173 DOI: 10.1523/Jneurosci.0148-16.2016  0.442
2016 Gurnik S, Devraj K, Macas J, Yamaji M, Starke J, Scholz A, Sommer K, Di Tacchio M, Vutukuri R, Beck H, Mittelbronn M, Foerch C, Pfeilschifter W, Liebner S, Peters KG, et al. Angiopoietin-2-induced blood-brain barrier compromise and increased stroke size are rescued by VE-PTP-dependent restoration of Tie2 signaling. Acta Neuropathologica. 131: 753-73. PMID 26932603 DOI: 10.1007/S00401-016-1551-3  0.461
2015 Devraj K, Poznanovic S, Spahn C, Schwall G, Harter PN, Mittelbronn M, Antoniello K, Paganetti P, Muhs A, Heilemann M, Hawkins RA, Schrattenholz A, Liebner S. BACE-1 is expressed in the blood-brain barrier endothelium and is upregulated in a murine model of Alzheimer's disease. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 26661166 DOI: 10.1177/0271678X15606463  0.453
2015 Simpson IA, Ponnuru P, Klinger ME, Myers RL, Devraj K, Coe CL, Lubach GR, Carruthers A, Connor JR. A novel model for brain iron uptake: introducing the concept of regulation. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 35: 48-57. PMID 25315861 DOI: 10.1038/Jcbfm.2014.168  0.339
2014 Feng Y, Gross S, Wolf NM, Butenschön VM, Qiu Y, Devraj K, Liebner S, Kroll J, Skolnik EY, Hammes HP, Wieland T. Nucleoside diphosphate kinase B regulates angiogenesis through modulation of vascular endothelial growth factor receptor type 2 and endothelial adherens junction proteins. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 2292-300. PMID 25147336 DOI: 10.1161/Atvbaha.114.304239  0.396
2014 Ridder K, Keller S, Dams M, Rupp AK, Schlaudraff J, Turco DD, Starmann J, Macas J, Karpova D, Devraj K, Depboylu C, Landfried B, Arnold B, Plate KH, Höglinger G, et al. Extracellular vesicle-mediated transfer of genetic information between the hematopoietic system and the brain in response to inflammation. Plos Biology. 12: e1001874. PMID 24893313 DOI: 10.1371/Journal.Pbio.1001874  0.34
2014 Liu H, Devraj K, Möller K, Liebner S, Hecker M, Korff T. EphrinB-mediated reverse signalling controls junctional integrity and pro-inflammatory differentiation of endothelial cells Thrombosis and Haemostasis. 112: 151-163. PMID 24522257 DOI: 10.1160/Th13-12-1034  0.369
2014 Czupalla CJ, Liebner S, Devraj K. In vitro models of the blood-brain barrier. Methods in Molecular Biology (Clifton, N.J.). 1135: 415-37. PMID 24510883 DOI: 10.1007/978-1-4939-0320-7_34  0.444
2014 Paganetti P, Antoniello K, Devraj K, Toni N, Kieran D, Madani R, Pihlgren M, Adolfsson O, Froestl W, Schrattenholz A, Liebner S, Havas D, Windisch M, Cirrito JR, Pfeifer A, et al. Increased efflux of amyloid-β peptides through the blood-brain barrier by muscarinic acetylcholine receptor inhibition reduces pathological phenotypes in mouse models of brain amyloidosis. Journal of Alzheimer's Disease : Jad. 38: 767-86. PMID 24072071 DOI: 10.3233/Jad-131091  0.43
2013 Paolinelli R, Corada M, Ferrarini L, Devraj K, Artus C, Czupalla CJ, Rudini N, Maddaluno L, Papa E, Engelhardt B, Couraud PO, Liebner S, Dejana E. Wnt activation of immortalized brain endothelial cells as a tool for generating a standardized model of the blood brain barrier in vitro. Plos One. 8: e70233. PMID 23940549 DOI: 10.1371/Journal.Pone.0070233  0.448
2012 Reis M, Czupalla CJ, Ziegler N, Devraj K, Zinke J, Seidel S, Heck R, Thom S, Macas J, Bockamp E, Fruttiger M, Taketo MM, Dimmeler S, Plate KH, Liebner S. Endothelial Wnt/β-catenin signaling inhibits glioma angiogenesis and normalizes tumor blood vessels by inducing PDGF-B expression. The Journal of Experimental Medicine. 209: 1611-27. PMID 22908324 DOI: 10.1084/Jem.20111580  0.399
2012 Reis M, Czupalla CJ, Ziegler N, Devraj K, Seidel S, Heck R, Thom S, Macas J, Bockamp E, Dimmeler S, Plate KH, Liebner S. Endothelial Wnt/β-catenin signaling reduces vascularization, barrier breakdown and tumor growth in a mouse glioma model Vascular Pharmacology. 56: 332. DOI: 10.1016/J.Vph.2011.08.078  0.362
2011 Devraj K, Klinger ME, Myers RL, Mokashi A, Hawkins RA, Simpson IA. GLUT-1 glucose transporters in the blood-brain barrier: differential phosphorylation. Journal of Neuroscience Research. 89: 1913-25. PMID 21910135 DOI: 10.1002/Jnr.22738  0.367
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