| Year |
Citation |
Score |
| 2023 |
Bumbak F, Bower JB, Zemmer SC, Inoue A, Pons M, Paniagua JC, Yan F, Ford J, Wu H, Robson SA, Bathgate RAD, Scott DJ, Gooley PR, Ziarek JJ. Stabilization of pre-existing neurotensin receptor conformational states by β-arrestin-1 and the biased allosteric modulator ML314. Nature Communications. 14: 3328. PMID 37286565 DOI: 10.1038/s41467-023-38894-8 |
0.358 |
|
| 2023 |
Kahraman K, Robson SA, Göcenler O, Tozkoparan CD, Klein JM, Yenici CM, Haas AL, Ziarek JJ, Dağ Ç. Characterizing the monomer-dimer equilibrium of UbcH8/Ube2L6: A combined SAXS and NMR study. Biorxiv : the Preprint Server For Biology. PMID 37090523 DOI: 10.1101/2023.04.13.536743 |
0.765 |
|
| 2023 |
Bumbak F, Pons M, Inoue A, Paniagua JC, Yan F, Wu H, Robson SA, Bathgate RAD, Scott DJ, Gooley PR, Ziarek JJ. Ligands selectively tune the local and global motions of neurotensin receptor 1 (NTS). Cell Reports. 42: 112015. PMID 36680775 DOI: 10.1016/j.celrep.2023.112015 |
0.329 |
|
| 2022 |
Dixon AD, Inoue A, Robson SA, Culhane KJ, Trinidad JC, Sivaramakrishnan S, Bumbak F, Ziarek JJ. Effect of Ligands and Transducers on the Neurotensin Receptor 1 Conformational Ensemble. Journal of the American Chemical Society. PMID 35647863 DOI: 10.1021/jacs.2c00828 |
0.389 |
|
| 2021 |
Robson SA, Dağ Ç, Wu H, Ziarek JJ. TRACT revisited: an algebraic solution for determining overall rotational correlation times from cross-correlated relaxation rates. Journal of Biomolecular Nmr. PMID 34480265 DOI: 10.1007/s10858-021-00379-5 |
0.729 |
|
| 2018 |
Hitchinson B, Eby JM, Gao X, Guite-Vinet F, Ziarek JJ, Abdelkarim H, Lee Y, Okamoto Y, Shikano S, Majetschak M, Heveker N, Volkman BF, Tarasova NI, Gaponenko V. Biased antagonism of CXCR4 avoids antagonist tolerance. Science Signaling. 11. PMID 30327409 DOI: 10.1126/Scisignal.Aat2214 |
0.602 |
|
| 2018 |
Gruenhagen T, Ziarek JJ, Schlebach JP. Bicelle Size Modulates the Rate of Bacteriorhodopsin Folding. Protein Science : a Publication of the Protein Society. PMID 29604129 DOI: 10.1002/Pro.3414 |
0.309 |
|
| 2018 |
Chhabra S, Fischer P, Takeuchi K, Dubey A, Ziarek JJ, Boeszoermenyi A, Mathieu D, Bermel W, Davey NE, Wagner G, Arthanari H.
N detection harnesses the slow relaxation property of nitrogen: Delivering enhanced resolution for intrinsically disordered proteins. Proceedings of the National Academy of Sciences of the United States of America. PMID 29432148 DOI: 10.1073/Pnas.1717560115 |
0.526 |
|
| 2017 |
Ziarek JJ, Baptista D, Wagner G. Recent developments in solution nuclear magnetic resonance (NMR)-based molecular biology. Journal of Molecular Medicine (Berlin, Germany). PMID 28643003 DOI: 10.1007/S00109-017-1560-2 |
0.746 |
|
| 2017 |
Ziarek JJ, Kleist AB, London N, Raveh B, Montpas N, Bonneterre J, St-Onge G, DiCosmo-Ponticello CJ, Koplinski CA, Roy I, Stephens B, Thelen S, Veldkamp CT, Coffman FD, Cohen MC, et al. Structural basis for chemokine recognition by a G protein-coupled receptor and implications for receptor activation. Science Signaling. 10. PMID 28325822 DOI: 10.1126/Scisignal.Aah5756 |
0.78 |
|
| 2016 |
Kleist AB, Getschman AE, Ziarek JJ, Nevins AM, Gauthier PA, Chevigné A, Szpakowska M, Volkman BF. New paradigms in chemokine receptor signal transduction: moving beyond the two-site model. Biochemical Pharmacology. PMID 27106080 DOI: 10.1016/J.Bcp.2016.04.007 |
0.632 |
|
| 2016 |
Ziarek J, Peterson F, Volkman B. Structure of constitutively monomeric CXCL12 in complex with the CXCR4 N-terminus Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2N55/Pdb |
0.561 |
|
| 2016 |
Nihongi A, Ziarek JJ, Uttieri M, Sandulli R, Zambianchi E, Strickler JR. Behavioural interseasonal adaptations in Daphnia pulicaria (Crustacea: Cladocera) as induced by predation infochemicals Aquatic Ecology. 1-18. DOI: 10.1007/S10452-016-9585-0 |
0.542 |
|
| 2014 |
Smith EW, Liu Y, Getschman AE, Peterson FC, Ziarek JJ, Li R, Volkman BF, Chen Y. Structural analysis of a novel small molecule ligand bound to the CXCL12 chemokine. Journal of Medicinal Chemistry. 57: 9693-9. PMID 25356720 DOI: 10.1021/Jm501194P |
0.648 |
|
| 2014 |
Wommack AJ, Ziarek JJ, Tomaras J, Chileveru HR, Zhang Y, Wagner G, Nolan EM. Discovery and characterization of a disulfide-locked C(2)-symmetric defensin peptide. Journal of the American Chemical Society. 136: 13494-7. PMID 25181039 DOI: 10.1021/Ja505957W |
0.44 |
|
| 2014 |
Verkaar F, van Offenbeek J, van der Lee MM, van Lith LH, Watts AO, Rops AL, Aguilar DC, Ziarek JJ, van der Vlag J, Handel TM, Volkman BF, Proudfoot AE, Vischer HF, Zaman GJ, Smit MJ. Chemokine cooperativity is caused by competitive glycosaminoglycan binding. Journal of Immunology (Baltimore, Md. : 1950). 192: 3908-14. PMID 24639348 DOI: 10.4049/Jimmunol.1302159 |
0.627 |
|
| 2014 |
Luna RE, Akabayov SR, Ziarek JJ, Wagner G. Examining weak protein-protein interactions in start codon recognition via NMR spectroscopy. The Febs Journal. 281: 1965-73. PMID 24393460 DOI: 10.1111/Febs.12667 |
0.542 |
|
| 2013 |
Ziarek JJ, Getschman AE, Butler SJ, Taleski D, Stephens B, Kufareva I, Handel TM, Payne RJ, Volkman BF. Sulfopeptide probes of the CXCR4/CXCL12 interface reveal oligomer-specific contacts and chemokine allostery. Acs Chemical Biology. 8: 1955-63. PMID 23802178 DOI: 10.1021/Cb400274Z |
0.666 |
|
| 2013 |
Ziarek JJ, Veldkamp CT, Zhang F, Murray NJ, Kartz GA, Liang X, Su J, Baker JE, Linhardt RJ, Volkman BF. Heparin oligosaccharides inhibit chemokine (CXC motif) ligand 12 (CXCL12) cardioprotection by binding orthogonal to the dimerization interface, promoting oligomerization, and competing with the chemokine (CXC motif) receptor 4 (CXCR4) N terminus. The Journal of Biological Chemistry. 288: 737-46. PMID 23148226 DOI: 10.1074/Jbc.M112.394064 |
0.768 |
|
| 2012 |
Ziarek JJ, Liu Y, Smith E, Zhang G, Peterson FC, Chen J, Yu Y, Chen Y, Volkman BF, Li R. Fragment-based optimization of small molecule CXCL12 inhibitors for antagonizing the CXCL12/CXCR4 interaction. Current Topics in Medicinal Chemistry. 12: 2727-40. PMID 23368099 DOI: 10.2174/1568026611212240003 |
0.662 |
|
| 2012 |
Ziarek JJ, Volkman BF. NMR in the Analysis of Functional Chemokine Interactions and Drug Discovery. Drug Discovery Today. Technologies. 9: e293-e299. PMID 23166561 DOI: 10.1016/J.Ddtec.2012.04.003 |
0.654 |
|
| 2012 |
Takekoshi T, Ziarek JJ, Volkman BF, Hwang ST. A locked, dimeric CXCL12 variant effectively inhibits pulmonary metastasis of CXCR4-expressing melanoma cells due to enhanced serum stability. Molecular Cancer Therapeutics. 11: 2516-25. PMID 22869557 DOI: 10.1158/1535-7163.Mct-12-0494 |
0.569 |
|
| 2012 |
Mysinger MM, Weiss DR, Ziarek JJ, Gravel S, Doak AK, Karpiak J, Heveker N, Shoichet BK, Volkman BF. Structure-based ligand discovery for the protein-protein interface of chemokine receptor CXCR4. Proceedings of the National Academy of Sciences of the United States of America. 109: 5517-22. PMID 22431600 DOI: 10.1073/Pnas.1120431109 |
0.647 |
|
| 2012 |
Love M, Sandberg JL, Ziarek JJ, Gerarden KP, Rode RR, Jensen DR, McCaslin DR, Peterson FC, Veldkamp CT. Solution structure of CCL21 and identification of a putative CCR7 binding site. Biochemistry. 51: 733-5. PMID 22221265 DOI: 10.1021/Bi201601K |
0.757 |
|
| 2011 |
Drury LJ, Ziarek JJ, Gravel S, Veldkamp CT, Takekoshi T, Hwang ST, Heveker N, Volkman BF, Dwinell MB. Monomeric and dimeric CXCL12 inhibit metastasis through distinct CXCR4 interactions and signaling pathways. Proceedings of the National Academy of Sciences of the United States of America. 108: 17655-60. PMID 21990345 DOI: 10.1073/Pnas.1101133108 |
0.745 |
|
| 2011 |
Saini V, Staren DM, Ziarek JJ, Nashaat ZN, Campbell EM, Volkman BF, Marchese A, Majetschak M. The CXC chemokine receptor 4 ligands ubiquitin and stromal cell-derived factor-1α function through distinct receptor interactions. The Journal of Biological Chemistry. 286: 33466-77. PMID 21757744 DOI: 10.1074/Jbc.M111.233742 |
0.64 |
|
| 2011 |
Ziarek JJ, Heroux MS, Veldkamp CT, Peterson FC, Volkman BF. Sulfotyrosine recognition as marker for druggable sites in the extracellular space. International Journal of Molecular Sciences. 12: 3740-56. PMID 21747703 DOI: 10.3390/Ijms12063740 |
0.776 |
|
| 2011 |
Ziarek JJ, Peterson FC, Lytle BL, Volkman BF. Binding site identification and structure determination of protein-ligand complexes by NMR a semiautomated approach. Methods in Enzymology. 493: 241-75. PMID 21371594 DOI: 10.1016/B978-0-12-381274-2.00010-8 |
0.634 |
|
| 2011 |
Drury L, Ziarek J, Volkman BF, Dwinell MB. CXCL12 Oligomerization Dictates Divergent Signaling and Migratory Responses in Intestinal Epithelial Cells Gastroenterology. 140: S-645. DOI: 10.1016/S0016-5085(11)62670-X |
0.618 |
|
| 2011 |
Ziarek JJ, Nihongi A, Nagai T, Uttieri M, Strickler JR. Seasonal adaptations of Daphnia pulicaria swimming behaviour: The effect of water temperature Hydrobiologia. 661: 317-327. DOI: 10.1007/S10750-010-0540-0 |
0.523 |
|
| 2011 |
Nihongi A, Ziarek JJ, Nagai T, Uttieri M, Zambianchi E, Strickler JR. Daphnia pulicaria hijacked by Vibrio cholerae: Altered swimming behaviour and predation risk implications Zooplankton and Phytoplankton: Types, Characteristics and Ecology. 181-192. |
0.477 |
|
| 2010 |
Veldkamp CT, Ziarek JJ, Peterson FC, Chen Y, Volkman BF. Targeting SDF-1/CXCL12 with a ligand that prevents activation of CXCR4 through structure-based drug design. Journal of the American Chemical Society. 132: 7242-3. PMID 20459090 DOI: 10.1021/Ja1002263 |
0.771 |
|
| 2009 |
Veldkamp CT, Ziarek JJ, Su J, Basnet H, Lennertz R, Weiner JJ, Peterson FC, Baker JE, Volkman BF. Monomeric structure of the cardioprotective chemokine SDF-1/CXCL12. Protein Science : a Publication of the Protein Society. 18: 1359-69. PMID 19551879 DOI: 10.1002/Pro.167 |
0.764 |
|
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