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Ara M. Abramyan, Ph.D. - Publications

Affiliations: 
2014 Chemistry and Biochemistry University of the Sciences in Philadelphia 
Area:
Biochemistry, General Biophysics
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20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Plenge P, Abramyan AM, Sørensen G, Mørk A, Weikop P, Gether U, Bang-Andersen B, Shi L, Loland CJ. The mechanism of a high-affinity allosteric inhibitor of the serotonin transporter. Nature Communications. 11: 1491. PMID 32198394 DOI: 10.1038/S41467-020-15292-Y  0.363
2020 Abramyan AM, Yano H, Xu M, Liu L, Naing S, Fant AD, Shi L. The Glu102 mutation disrupts higher-order oligomerization of the sigma 1 receptor. Computational and Structural Biotechnology Journal. 18: 199-206. PMID 32055286 DOI: 10.1016/J.Csbj.2019.12.012  0.374
2020 Lane JR, Abramyan AM, Adhikari P, Keen AC, Lee KH, Sanchez J, Verma RK, Lim HD, Yano H, Javitch JA, Shi L. Distinct inactive conformations of the dopamine D2 and D3 receptors correspond to different extents of inverse agonism. Elife. 9. PMID 31985399 DOI: 10.7554/Elife.52189  0.421
2019 Slack RD, Abramyan AM, Tang H, Meena S, Davis BA, Bonifazi A, Giancola JB, Deschamps JR, Naing S, Yano H, Singh SKK, Newman AH, Shi L. A novel Bromine-containing paroxetine analog provides mechanistic clues for binding ambiguity at the central primary binding site of the serotonin transporter. Acs Chemical Neuroscience. PMID 31424193 DOI: 10.1021/Acschemneuro.9B00375  0.38
2018 Abramyan AM, Slack RD, Meena S, Davis BA, Newman AH, Singh SK, Shi L. Computation-guided analysis of paroxetine binding to hSERT reveals functionally important structural elements and dynamics. Neuropharmacology. PMID 30391505 DOI: 10.1016/J.Neuropharm.2018.10.040  0.392
2018 Quick M, Abramyan AM, Wiriyasermkul P, Weinstein H, Shi L, Javitch JA. The LeuT-fold neurotransmitter:sodium symporter MhsT has two substrate sites. Proceedings of the National Academy of Sciences of the United States of America. PMID 30082383 DOI: 10.1073/Pnas.1717444115  0.336
2018 Abramyan AM, Quick M, Xue C, Javitch JA, Shi L. Exploring substrate binding in the extracellular vestibule of MhsT by atomistic simulations and Markov models. Journal of Chemical Information and Modeling. PMID 29851339 DOI: 10.1021/Acs.Jcim.8B00175  0.41
2018 Yano H, Bonifazi A, Xu M, Guthrie DA, Schneck SN, Abramyan AM, Fant AD, Hong WC, Newman AH, Shi L. Pharmacological profiling of sigma 1 receptor ligands by novel receptor homomer assays. Neuropharmacology. PMID 29407216 DOI: 10.1016/J.Neuropharm.2018.01.042  0.379
2018 Draper-Joyce CJ, Verma RK, Michino M, Shonberg J, Kopinathan A, Klein Herenbrink C, Scammells PJ, Capuano B, Abramyan AM, Thal DM, Javitch JA, Christopoulos A, Shi L, Lane JR. The action of a negative allosteric modulator at the dopamine D2 receptor is dependent upon sodium ions. Scientific Reports. 8: 1208. PMID 29352161 DOI: 10.1038/S41598-018-19642-1  0.368
2018 Verma RK, Abramyan AM, Michino M, Free RB, Sibley DR, Javitch JA, Lane JR, Shi L. The E2.65A mutation disrupts dynamic binding poses of SB269652 at the dopamine D2 and D3 receptors. Plos Computational Biology. 14: e1005948. PMID 29337986 DOI: 10.1371/Journal.Pcbi.1005948  0.407
2017 Abramyan AM, Stolzenberg S, Li Z, Loland CJ, Noé F, Shi L. The isomeric preference of an atypical dopamine transporter inhibitor contributes to its selection of the transporter conformation. Acs Chemical Neuroscience. PMID 28441487 DOI: 10.1021/Acschemneuro.7B00094  0.413
2017 Ton HT, Phan TX, Abramyan AM, Shi L, Ahern GP. Identification of a putative binding site critical for general anesthetic activation of TRPA1. Proceedings of the National Academy of Sciences of the United States of America. PMID 28320952 DOI: 10.1073/Pnas.1618144114  0.365
2017 Abramyan AM, Xue C, Shi L. Exploring Ligand-Binding Kinetics in the S2 Site of MhsT by Atomistic Simulations and Markov Models Biophysical Journal. 112: 127a. DOI: 10.1016/J.Bpj.2016.11.711  0.407
2017 Liu Z, Hu X, Abramyan AM, Mészáros Á, Csékei M, Kotschy A, Huc I, Pophristic V. Inside Cover: Computational Prediction and Rationalization, and Experimental Validation of Handedness Induction in Helical Aromatic Oligoamide Foldamers (Chem. Eur. J. 15/2017) Chemistry - a European Journal. 23: 3500-3500. DOI: 10.1002/Chem.201700131  0.635
2016 Liu Z, Hu X, Abramyan AM, Mészáros Á, Csekei M, Kotschy A, Huc I, Pophristic V. Computational prediction and rationalization, and experimental validation of handedness induction in helical aromatic oligoamide foldamers. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27935190 DOI: 10.1002/Chem.201605082  0.66
2016 Abramyan AM, Taro N, Stolzenberg S, Shi L. Towards Identifying Biologically Relevant Intermediate Conformational States in Dopamine Transporter Biophysical Journal. 110: 626. DOI: 10.1016/J.Bpj.2015.11.3356  0.328
2015 Abramyan AM, Liu Z, Pophristic V. Helix handedness inversion in arylamide foldamers: elucidation and free energy profile of a hopping mechanism. Chemical Communications (Cambridge, England). PMID 26507120 DOI: 10.1039/C5Cc07060K  0.632
2015 Liu Z, Abramyan AM, Pophristic V. Helical arylamide foldamers: Structure prediction by molecular dynamics simulations New Journal of Chemistry. 39: 3229-3240. DOI: 10.1039/C4Nj01925C  0.671
2014 Abramyan AM, Liu Z, Pophristic V. Mechanistic and dynamic insights into ligand encapsulation by helical arylamide foldamers. Physical Chemistry Chemical Physics : Pccp. 16: 20406-10. PMID 25155970 DOI: 10.1039/C4Cp02839B  0.671
2013 Abramyan AM, Liu Z, Pophristic V. An ab-initio study of pyrrole and imidazole arylamides Journal of the Serbian Chemical Society. 78: 1789-1795. DOI: 10.2298/Jsc130929104A  0.652
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