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Erwin F. Wagner, PhD (Dr. rer. nat. ) - Publications

Affiliations: 
BBVA Foundation – CNIO Cancer Cell Biology Programme CNIO, Madrid, Comunidad de Madrid, Spain 
Area:
AP-1
Website:
http://www.cnio.es/ing/grupos/plantillas/curriculum.asp?pag=890

292 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Vitale I, Pietrocola F, Guilbaud E, Aaronson SA, Abrams JM, Adam D, Agostini M, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Aqeilan RI, Arama E, Baehrecke EH, ... ... Wagner EF, et al. Apoptotic cell death in disease-Current understanding of the NCCD 2023. Cell Death and Differentiation. PMID 37100955 DOI: 10.1038/s41418-023-01153-w  0.418
2020 Matsuoka K, Bakiri L, Wolff LI, Linder M, Mikels-Vigdal A, Patiño-García A, Lecanda F, Hartmann C, Sibilia M, Wagner EF. Wnt signaling and Loxl2 promote aggressive osteosarcoma. Cell Research. PMID 32686768 DOI: 10.1038/S41422-020-0370-1  0.443
2019 Uluçkan Ö, Jiménez M, Roediger B, Schnabl J, Díez-Córdova LT, Troulé K, Weninger W, Wagner EF. Cutaneous Immune Cell-Microbiota Interactions Are Controlled by Epidermal JunB/AP-1. Cell Reports. 29: 844-859.e3. PMID 31644908 DOI: 10.1016/J.Celrep.2019.09.042  0.32
2019 Gago-Lopez N, Mellor LF, Megías D, Martín-Serrano G, Izeta A, Jimenez F, Wagner EF. Role of bulge epidermal stem cells and TSLP signaling in psoriasis. Embo Molecular Medicine. e10697. PMID 31556482 DOI: 10.15252/Emmm.201910697  0.401
2019 Ucero AC, Bakiri L, Roediger B, Suzuki M, Jimenez M, Mandal P, Braghetta P, Bonaldo P, Paz-Ares L, Fustero-Torre C, Ximenez-Embun P, Hernandez AI, Megias D, Wagner EF. Fra-2-expressing macrophages promote lung fibrosis in mice. The Journal of Clinical Investigation. 130. PMID 31135379 DOI: 10.1172/Jci125366  0.336
2018 Linder M, Glitzner E, Srivatsa S, Bakiri L, Matsuoka K, Shahrouzi P, Dumanic M, Novoszel P, Mohr T, Langer O, Wanek T, Mitterhauser M, Wagner EF, Sibilia M. EGFR is required for FOS-dependent bone tumor development via RSK2/CREB signaling. Embo Molecular Medicine. PMID 30361264 DOI: 10.15252/Emmm.201809408  0.363
2018 Luo Y, Grötsch B, Hannemann N, Jimenez M, Ipseiz N, Uluckan O, Lin N, Schett G, Wagner EF, Bozec A. Fra-2 expression in osteoblasts regulates systemic inflammation and lung injury through osteopontin. Molecular and Cellular Biology. PMID 30181393 DOI: 10.1128/Mcb.00022-18  0.362
2018 Soler-Cardona A, Forsthuber A, Lipp K, Ebersberger S, Heinz M, Schossleitner K, Buchberger E, Gröger M, Petzelbauer P, Hoeller C, Wagner E, Loewe R. CXCL5 facilitates melanoma cell-neutrophil interaction and lymph node metastasis. The Journal of Investigative Dermatology. PMID 29474942 DOI: 10.1016/J.Jid.2018.01.035  0.314
2018 Linder M, Hecking M, Glitzner E, Zwerina K, Holcmann M, Bakiri L, Ruocco MG, Tuckermann J, Schett G, Wagner EF, Sibilia M. EGFR controls bone development by negatively regulating mTOR-signaling during osteoblast differentiation. Cell Death and Differentiation. PMID 29445126 DOI: 10.1038/S41418-017-0054-7  0.376
2018 Cobo I, Martinelli P, Flández M, Bakiri L, Zhang M, Carrillo-de-Santa-Pau E, Jia J, Sánchez-Arévalo Lobo VJ, Megías D, Felipe I, Del Pozo N, Millán I, Thommesen L, Bruland T, Olson SH, ... ... Wagner EF, et al. Transcriptional regulation by NR5A2 links differentiation and inflammation in the pancreas. Nature. PMID 29443959 DOI: 10.1038/Nature25751  0.371
2018 Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, ... ... Wagner EF, et al. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell Death and Differentiation. PMID 29362479 DOI: 10.1038/S41418-017-0012-4  0.461
2018 Ucero A, Bakiri L, Suzuki M, Fustero-Torre C, Ximenez-Embun P, Hernandez A, Wagner E. Collagen-producing macrophages can mediate lung fibrosis throughFra-2/AP-1 expression European Respiratory Journal. 52. DOI: 10.1183/13993003.Congress-2018.Lsc-1216  0.342
2017 Tsujino K, Li JT, Tsukui T, Ren X, Bakiri L, Wagner EF, Sheppard D. Fra-2 negatively regulates postnatal alveolar septation by modulating myofibroblast function. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00062.2017. PMID 28818870 DOI: 10.1152/Ajplung.00062.2017  0.419
2017 Bakiri L, Hamacher R, Graña O, Guío-Carrión A, Campos-Olivas R, Martinez L, Dienes HP, Thomsen MK, Hasenfuss SC, Wagner EF. Liver carcinogenesis by FOS-dependent inflammation and cholesterol dysregulation. The Journal of Experimental Medicine. PMID 28356389 DOI: 10.1084/Jem.20160935  0.373
2017 Linder M, Glitzner E, Srivatsa S, Shahrouzi P, Bakiri L, Dumanic M, Mitterhauser M, Wagner EF, Sibilia M. Abstract 530: The role of EGFR in c-fos-dependent osteosarcoma formation Cancer Research. 77: 530-530. DOI: 10.1158/1538-7445.Am2017-530  0.307
2016 Blanpain C, Wagner EF. Editorial Overview: The ins and outs of stem cells in differentiation, inflammation & disease. Current Opinion in Cell Biology. 43: iv-vi. PMID 27955754 DOI: 10.1016/J.Ceb.2016.10.004  0.302
2016 Fan F, Bashari MH, Morelli E, Tonon G, Malvestiti S, Vallet S, Jarahian M, Seckinger A, Hose D, Bakiri L, Sun C, Hu Y, Ball CR, Glimm H, Sattler M, ... ... Wagner EF, et al. The AP-1 transcription factor JunB is essential for multiple myeloma cell proliferation and drug resistance in the bone marrow microenvironment. Leukemia. PMID 27890927 DOI: 10.1038/Leu.2016.358  0.403
2016 Uluçkan Ö, Jimenez M, Karbach S, Jeschke A, Graña O, Keller J, Busse B, Croxford AL, Finzel S, Koenders M, van den Berg W, Schinke T, Amling M, Waisman A, Schett G, ... Wagner EF, et al. Chronic skin inflammation leads to bone loss by IL-17-mediated inhibition of Wnt signaling in osteoblasts. Science Translational Medicine. 8: 330ra37. PMID 27089206 DOI: 10.1126/Scitranslmed.Aad8996  0.318
2016 Puujalka E, Heinz M, Hoesel B, Friedl P, Schweighofer B, Wenzina J, Pirker C, Schmid JA, Loewe R, Wagner EF, Berger W, Petzelbauer P. Opposing roles of JNK and p38 in lymphangiogenesis in melanoma. The Journal of Investigative Dermatology. PMID 26829032 DOI: 10.1016/J.Jid.2016.01.020  0.36
2016 Bakiri L, Wagner EF. News and views on EMT Fra-1 controls EMT in mammary epithelial cells Molecular & Cellular Oncology. 3: e990307. DOI: 10.4161/23723556.2014.990307  0.356
2016 Malvestiti S, Fan F, Bashari MH, Morelli E, Vallet S, Sattler M, Bakiri L, Seckinger A, Hose D, Goldschmidt H, Zörnig I, Pecherstorfer M, Wagner E, Tassone P, Jäger D, et al. The Pathophysiologic Role of JunB in Multiple Myeloma Pathogenesis: Focus on Bone Marrow Angiogenesis Blood. 128: 2091-2091. DOI: 10.1182/Blood.V128.22.2091.2091  0.362
2016 Fan F, Vallet S, Bashari MH, Jarahian M, Morelli E, Hose D, Bakiri L, Ball C, Glimm H, Sattler M, Goldschmidt H, Tonon G, Tassone P, Wagner EF, Jäger D, et al. Abstract 2912: The AP-1 transcription factor JunB promotes multiple myeloma cell proliferation, survival and drug resistance in the bone marrow microenvironment Cancer Research. 76: 2912-2912. DOI: 10.1158/1538-7445.Am2016-2912  0.437
2015 Nowell CS, Odermatt PD, Azzolin L, Hohnel S, Wagner EF, Fantner GE, Lutolf MP, Barrandon Y, Piccolo S, Radtke F. Chronic inflammation imposes aberrant cell fate in regenerating epithelia through mechanotransduction. Nature Cell Biology. PMID 26689676 DOI: 10.1038/Ncb3290  0.324
2015 Trierweiler C, Hockenjos B, Zatloukal K, Thimme R, Blum HE, Wagner EF, Hasselblatt P. The transcription factor c-JUN/AP-1 promotes HBV-related liver tumorigenesis in mice. Cell Death and Differentiation. PMID 26470729 DOI: 10.1016/S0168-8278(13)60087-2  0.357
2015 Matsuo K, Kuroda Y, Nango N, Shimoda K, Kubota Y, Ema M, Bakiri L, Wagner EF, Takeda Y, Yashiro W, Momose A. Osteogenic capillaries orchestrate growth plate-independent ossification of the malleus. Development (Cambridge, England). PMID 26428006 DOI: 10.1242/Dev.123885  0.332
2015 Uluçkan Ö, Bakiri L, Wagner EF. Characterization of mouse model-derived osteosarcoma (OS) cells in vitro and in vivo. Methods in Molecular Biology (Clifton, N.J.). 1267: 297-305. PMID 25636475 DOI: 10.1007/978-1-4939-2297-0_14  0.323
2015 Wurm S, Zhang J, Guinea-Viniegra J, García F, Muñoz J, Bakiri L, Ezhkova E, Wagner EF. Terminal epidermal differentiation is regulated by the interaction of Fra-2/AP-1 with Ezh2 and ERK1/2. Genes & Development. 29: 144-56. PMID 25547114 DOI: 10.1101/Gad.249748.114  0.401
2015 Bakiri L, Macho-Maschler S, Custic I, Niemiec J, Guío-Carrión A, Hasenfuss SC, Eger A, Müller M, Beug H, Wagner EF. Fra-1/AP-1 induces EMT in mammary epithelial cells by modulating Zeb1/2 and TGFβ expression. Cell Death and Differentiation. 22: 336-50. PMID 25301070 DOI: 10.1038/Cdd.2014.157  0.426
2015 Galluzzi L, Bravo-San Pedro JM, Vitale I, Aaronson SA, Abrams JM, Adam D, Alnemri ES, Altucci L, Andrews D, Annicchiarico-Petruzzelli M, Baehrecke EH, Bazan NG, Bertrand MJ, Bianchi K, Blagosklonny MV, ... ... Wagner EF, et al. Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell Death and Differentiation. 22: 58-73. PMID 25236395 DOI: 10.1038/Cdd.2014.137  0.335
2015 Cobo I, Martinelli P, Carrillo E, Bakiri L, Wagner E, Real FX. Nr5a2 restrains an inflammatory program in the pancreas through the regulation of AP-1 activity Pancreatology. 15: S47. DOI: 10.1016/J.Pan.2015.05.193  0.317
2015 Fan F, Vallet S, Sattler M, Tonon G, Bashari MH, Bakiri L, Jarahian M, Roccaro A, Ghobrial I, Ball C, Glimm H, Anderson KC, Goldschmidt H, Wagner EF, Jaeger D, et al. The AP-1 Transcription Factor JunB Promotes Multiple Myeloma (MM) Cell Proliferation, Survival and Drug Resistance in the Bone Marrow Microenvironment Clinical Lymphoma, Myeloma & Leukemia. 15. DOI: 10.1016/J.Clml.2015.07.465  0.338
2014 Hefetz-Sela S, Stein I, Klieger Y, Porat R, Sade-Feldman M, Zreik F, Nagler A, Pappo O, Quagliata L, Dazert E, Eferl R, Terracciano L, Wagner EF, Ben-Neriah Y, Baniyash M, et al. Acquisition of an immunosuppressive protumorigenic macrophage phenotype depending on c-Jun phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 111: 17582-7. PMID 25422452 DOI: 10.1073/Pnas.1409700111  0.377
2014 Grötsch B, Brachs S, Lang C, Luther J, Derer A, Schlötzer-Schrehardt U, Bozec A, Fillatreau S, Berberich I, Hobeika E, Reth M, Wagner EF, Schett G, Mielenz D, David JP. The AP-1 transcription factor Fra1 inhibits follicular B cell differentiation into plasma cells. The Journal of Experimental Medicine. 211: 2199-212. PMID 25288397 DOI: 10.1084/Jem.20130795  0.4
2014 Glitzner E, Korosec A, Brunner PM, Drobits B, Amberg N, Schonthaler HB, Kopp T, Wagner EF, Stingl G, Holcmann M, Sibilia M. Specific roles for dendritic cell subsets during initiation and progression of psoriasis. Embo Molecular Medicine. 6: 1312-27. PMID 25216727 DOI: 10.15252/Emmm.201404114  0.344
2014 Schulze J, Lopez-Contreras AJ, Uluçkan Ö, Graña-Castro O, Fernandez-Capetillo O, Wagner EF. Fos-dependent induction of Chk1 protects osteoblasts from replication stress. Cell Cycle (Georgetown, Tex.). 13: 1980-6. PMID 24762558 DOI: 10.4161/Cc.28923  0.383
2014 Bakiri L, Hasenfuss SC, Wagner EF. A FATal AP-1 dimer switch in hepatosteatosis. Cell Cycle (Georgetown, Tex.). 13: 1218-9. PMID 24621495 DOI: 10.4161/Cc.28514  0.415
2014 Guinea-Viniegra J, Jiménez M, Schonthaler HB, Navarro R, Delgado Y, Concha-Garzón MJ, Tschachler E, Obad S, Daudén E, Wagner EF. Targeting miR-21 to treat psoriasis. Science Translational Medicine. 6: 225re1. PMID 24574341 DOI: 10.1126/Scitranslmed.3008089  0.301
2014 Luther J, Ubieta K, Hannemann N, Jimenez M, Garcia M, Zech C, Schett G, Wagner EF, Bozec A. Fra-2/AP-1 controls adipocyte differentiation and survival by regulating PPARγ and hypoxia. Cell Death and Differentiation. 21: 655-64. PMID 24464219 DOI: 10.1038/Cdd.2013.198  0.403
2014 Hasenfuss SC, Bakiri L, Thomsen MK, Williams EG, Auwerx J, Wagner EF. Regulation of steatohepatitis and PPARγ signaling by distinct AP-1 dimers. Cell Metabolism. 19: 84-95. PMID 24411941 DOI: 10.1016/J.Cmet.2013.11.018  0.352
2014 Schumacher M, Schuster C, Rogon ZM, Bauer T, Caushaj N, Baars S, Szabowski S, Bauer C, Schorpp-Kistner M, Hess J, Holland-Cunz S, Wagner EF, Eils R, Angel P, Hartenstein B. Efficient keratinocyte differentiation strictly depends on JNK-induced soluble factors in fibroblasts. The Journal of Investigative Dermatology. 134: 1332-41. PMID 24335928 DOI: 10.1038/Jid.2013.535  0.386
2014 Palla AR, Piazzolla D, Abad M, Li H, Dominguez O, Schonthaler HB, Wagner EF, Serrano M. Reprogramming activity of NANOGP8, a NANOG family member widely expressed in cancer. Oncogene. 33: 2513-9. PMID 23752184 DOI: 10.1038/Onc.2013.196  0.378
2014 Hasenfuss SC, Bakiri L, Thomsen MK, Hamacher R, Wagner EF. Activator Protein 1 transcription factor Fos-related antigen 1 (Fra-1) is dispensable for murine liver fibrosis, but modulates xenobiotic metabolism. Hepatology (Baltimore, Md.). 59: 261-73. PMID 23703832 DOI: 10.1002/Hep.26518  0.335
2014 Fan F, Vallet S, Sattler M, Tonon G, Bashari MH, Bakiri L, Goldschmidt H, Wagner EF, Jaeger D, Podar K. The AP-1 Transcription Factor JunB Promotes Multiple Myeloma (MM) Cell Proliferation, Survival and Drug Resistance in the Bone Marrow Microenvironment Blood. 124: 3446-3446. DOI: 10.1182/Blood.V124.21.3446.3446  0.415
2014 Fan F, Vallet S, Sattler M, Tonon G, Bashari MH, Bakiri L, Goldschmidt H, Wagner EF, Jaeger D, Podar K. Abstract 3383: JunB/AP-1 controls MM cell proliferation, survival and drug resistance in the bone marrow microenvironment Cancer Research. 74: 3383-3383. DOI: 10.1158/1538-7445.Am2014-3383  0.41
2014 Wurm S, Guinea-Viniegra J, Zhang J, Ezhkova E, Wagner EF. Abstract 2336: Interplay of Fra-2/AP-1 and Ezh2/PRC2 orchestrates epidermal differentiation Cancer Research. 74: 2336-2336. DOI: 10.1158/1538-7445.Am2014-2336  0.368
2013 Schonthaler HB, Guinea-Viniegra J, Wculek SK, Ruppen I, Ximénez-Embún P, Guío-Carrión A, Navarro R, Hogg N, Ashman K, Wagner EF. S100A8-S100A9 protein complex mediates psoriasis by regulating the expression of complement factor C3. Immunity. 39: 1171-81. PMID 24332034 DOI: 10.1016/J.Immuni.2013.11.011  0.371
2013 Thomsen MK, Bakiri L, Hasenfuss SC, Hamacher R, Martinez L, Wagner EF. JUNB/AP-1 controls IFN-γ during inflammatory liver disease. The Journal of Clinical Investigation. 123: 5258-68. PMID 24200694 DOI: 10.1172/Jci70405  0.387
2013 Bozec A, Bakiri L, Jimenez M, Rosen ED, Catalá-Lehnen P, Schinke T, Schett G, Amling M, Wagner EF. Osteoblast-specific expression of Fra-2/AP-1 controls adiponectin and osteocalcin expression and affects metabolism. Journal of Cell Science. 126: 5432-40. PMID 24046454 DOI: 10.1242/Jcs.134510  0.378
2013 Windak R, Müller J, Felley A, Akhmedov A, Wagner EF, Pedrazzini T, Sumara G, Ricci R. The AP-1 transcription factor c-Jun prevents stress-imposed maladaptive remodeling of the heart. Plos One. 8: e73294. PMID 24039904 DOI: 10.1371/Journal.Pone.0073294  0.352
2013 Briso EM, Guinea-Viniegra J, Bakiri L, Rogon Z, Petzelbauer P, Eils R, Wolf R, Rincón M, Angel P, Wagner EF. Inflammation-mediated skin tumorigenesis induced by epidermal c-Fos. Genes & Development. 27: 1959-73. PMID 24029918 DOI: 10.1101/Gad.223339.113  0.377
2013 Evellin S, Galvagni F, Zippo A, Neri F, Orlandini M, Incarnato D, Dettori D, Neubauer S, Kessler H, Wagner EF, Oliviero S. FOSL1 controls the assembly of endothelial cells into capillary tubes by direct repression of αv and β3 integrin transcription. Molecular and Cellular Biology. 33: 1198-209. PMID 23319049 DOI: 10.1128/Mcb.01054-12  0.369
2013 Bozec A, Luo Y, Zech C, Jimenez M, Bakiri L, Petrucelli M, Amling M, Schett G, Wagner E. A4.9 How Osteoblast Regulates Energy Metabolism and Systemic Inflammation Dependent of FRA-2 Expression Annals of the Rheumatic Diseases. 72: A27.1-A27. DOI: 10.1136/Annrheumdis-2013-203217.9  0.376
2012 Min L, Ji Y, Bakiri L, Qiu Z, Cen J, Chen X, Chen L, Scheuch H, Zheng H, Qin L, Zatloukal K, Hui L, Wagner EF. Liver cancer initiation is controlled by AP-1 through SIRT6-dependent inhibition of survivin. Nature Cell Biology. 14: 1203-11. PMID 23041974 DOI: 10.1038/Ncb2590  0.369
2012 Ciofani M, Madar A, Galan C, Sellars M, Mace K, Pauli F, Agarwal A, Huang W, Parkurst CN, Muratet M, Newberry KM, Meadows S, Greenfield A, Yang Y, Jain P, ... ... Wagner EF, et al. A validated regulatory network for Th17 cell specification. Cell. 151: 289-303. PMID 23021777 DOI: 10.1016/J.Cell.2012.09.016  0.332
2012 Guinea-Viniegra J, Zenz R, Scheuch H, Jiménez M, Bakiri L, Petzelbauer P, Wagner EF. Differentiation-induced skin cancer suppression by FOS, p53, and TACE/ADAM17. The Journal of Clinical Investigation. 122: 2898-910. PMID 22772468 DOI: 10.1172/Jci63103  0.365
2012 Wrann CD, Eguchi J, Bozec A, Xu Z, Mikkelsen T, Gimble J, Nave H, Wagner EF, Ong SE, Rosen ED. FOSL2 promotes leptin gene expression in human and mouse adipocytes. The Journal of Clinical Investigation. 122: 1010-21. PMID 22326952 DOI: 10.1172/Jci58431  0.407
2012 Schultze SM, Mairhofer A, Li D, Cen J, Beug H, Wagner EF, Hui L. p38α controls erythroblast enucleation and Rb signaling in stress erythropoiesis. Cell Research. 22: 539-50. PMID 21946500 DOI: 10.1038/Cr.2011.159  0.323
2012 Gurzov EN, Barthson J, Marhfour I, Ortis F, Naamane N, Igoillo-Esteve M, Gysemans C, Mathieu C, Kitajima S, Marchetti P, Ørntoft TF, Bakiri L, Wagner EF, Eizirik DL. Pancreatic β-cells activate a JunB/ATF3-dependent survival pathway during inflammation. Oncogene. 31: 1723-32. PMID 21841823 DOI: 10.1038/Onc.2011.353  0.426
2012 Wagner E, Bakiri L, Bozec A. Functions of FOS/AP-1 proteins in bone development and beyond Bone. 51: S14. DOI: 10.1016/J.Bone.2012.08.042  0.305
2012 Uluckan⁎ O, Karbach S, Keller J, Amling M, Waisman A, Wagner E. Epidermal IL-17A leads to bone loss through inhibition of osteoblast differentiation Bone. 50: S31. DOI: 10.1016/J.Bone.2012.02.078  0.333
2011 Nakashima T, Hayashi M, Fukunaga T, Kurata K, Oh-Hora M, Feng JQ, Bonewald LF, Kodama T, Wutz A, Wagner EF, Penninger JM, Takayanagi H. Evidence for osteocyte regulation of bone homeostasis through RANKL expression. Nature Medicine. 17: 1231-4. PMID 21909105 DOI: 10.1038/Nm.2452  0.332
2011 Luther J, Driessler F, Megges M, Hess A, Herbort B, Mandic V, Zaiss MM, Reichardt A, Zech C, Tuckermann JP, Calkhoven CF, Wagner EF, Schett G, David JP. Elevated Fra-1 expression causes severe lipodystrophy. Journal of Cell Science. 124: 1465-76. PMID 21486951 DOI: 10.1242/Jcs.079855  0.445
2011 Takada Y, Gresh L, Bozec A, Ikeda E, Kamiya K, Watanabe M, Kobayashi K, Asano K, Toyama Y, Wagner EF, Matsuo K. Interstitial lung disease induced by gefitinib and toll-like receptor ligands is mediated by Fra-1. Oncogene. 30: 3821-32. PMID 21460858 DOI: 10.1038/Onc.2011.101  0.307
2011 Schonthaler HB, Guinea-Viniegra J, Wagner EF. Targeting inflammation by modulating the Jun/AP-1 pathway. Annals of the Rheumatic Diseases. 70: i109-12. PMID 21339212 DOI: 10.1136/Ard.2010.140533  0.41
2011 Fischer H, Szabo S, Scherz J, Jaeger K, Rossiter H, Buchberger M, Ghannadan M, Hermann M, Theussl HC, Tobin DJ, Wagner EF, Tschachler E, Eckhart L. Essential role of the keratinocyte-specific endonuclease DNase1L2 in the removal of nuclear DNA from hair and nails. The Journal of Investigative Dermatology. 131: 1208-15. PMID 21307874 DOI: 10.1038/Jid.2011.13  0.305
2011 Bakiri L, Reschke MO, Gefroh HA, Idarraga MH, Polzer K, Zenz R, Schett G, Wagner EF. Functions of Fos phosphorylation in bone homeostasis, cytokine response and tumourigenesis. Oncogene. 30: 1506-17. PMID 21119595 DOI: 10.1038/Onc.2010.542  0.416
2011 Katiyar S, Casimiro M, Dettin L, Ju X, Wagner E, Tanaka H, Pestell R. Abstract 202: Endogenous c-jun inhibits mammary epithelial cellular apoptosisin vivo Cancer Research. 71: 202-202. DOI: 10.1158/1538-7445.Am2011-202  0.399
2011 Wagner EF. Notch1 and corneal cell fate Developmental Cell. 21: e2. DOI: 10.1016/J.Devcel.2011.11.016  0.353
2010 Katiyar S, Casimiro MC, Dettin L, Ju X, Wagner EF, Tanaka H, Pestell RG. C-jun inhibits mammary apoptosis in vivo. Molecular Biology of the Cell. 21: 4264-74. PMID 20926681 DOI: 10.1091/Mbc.E10-08-0705  0.399
2010 Wagner EF, Schonthaler HB, Guinea-Viniegra J, Tschachler E. Psoriasis: what we have learned from mouse models. Nature Reviews. Rheumatology. 6: 704-14. PMID 20877306 DOI: 10.1038/Nrrheum.2010.157  0.308
2010 Bozec A, Bakiri L, Jimenez M, Schinke T, Amling M, Wagner EF. Fra-2/AP-1 controls bone formation by regulating osteoblast differentiation and collagen production. The Journal of Cell Biology. 190: 1093-106. PMID 20837772 DOI: 10.1083/Jcb.201002111  0.442
2010 Singh S, Vinson C, Gurley CM, Nolen GT, Beggs ML, Nagarajan R, Wagner EF, Parham DM, Peterson CA. Impaired Wnt signaling in embryonal rhabdomyosarcoma cells from p53/c-fos double mutant mice. The American Journal of Pathology. 177: 2055-66. PMID 20829439 DOI: 10.2353/Ajpath.2010.091195  0.454
2010 Meixner A, Karreth F, Kenner L, Penninger JM, Wagner EF. Jun and JunD-dependent functions in cell proliferation and stress response. Cell Death and Differentiation. 17: 1409-19. PMID 20300111 DOI: 10.1038/Cdd.2010.22  0.34
2010 Grigoriadis AE, Kennedy M, Bozec A, Brunton F, Stenbeck G, Park IH, Wagner EF, Keller GM. Directed differentiation of hematopoietic precursors and functional osteoclasts from human ES and iPS cells. Blood. 115: 2769-76. PMID 20065292 DOI: 10.1182/Blood-2009-07-234690  0.392
2010 Reschke M, Ferby I, Stepniak E, Seitzer N, Horst D, Wagner EF, Ullrich A. Mitogen-inducible gene-6 is a negative regulator of epidermal growth factor receptor signaling in hepatocytes and human hepatocellular carcinoma. Hepatology (Baltimore, Md.). 51: 1383-90. PMID 20044804 DOI: 10.1002/Hep.23428  0.384
2010 Takada Y, Ray N, Ikeda E, Kawaguchi T, Kuwahara M, Wagner EF, Matsuo K. Fos proteins suppress dextran sulfate sodium-induced colitis through inhibition of NF-kappaB. Journal of Immunology (Baltimore, Md. : 1950). 184: 1014-21. PMID 20018614 DOI: 10.4049/Jimmunol.0901196  0.389
2010 Wagner EF. Bone development and inflammatory disease is regulated by AP-1 (Fos/Jun). Annals of the Rheumatic Diseases. 69: i86-88. PMID 19995753 DOI: 10.1136/Ard.2009.119396  0.378
2010 Vaz M, Reddy NM, Wagner EF, Reddy SP. Abstract 1587: Targeted deletion of Fra-1 blocks oncogenic K-ras induced lung tumor development and progression in mice Cancer Research. 70: 1587-1587. DOI: 10.1158/1538-7445.Am10-1587  0.315
2010 Luther J, Driessler F, Megges M, Hess A, Herbort B, Mandic V, Zaiss M, Reichardt A, Zech C, Tuckermann J, Wagner E, Schett G, David J. Elevated FRA-1 expression causes severe lipodystrophy in the osteosclerotic FRA-1 transgenic mice Bone. 47: S118-S119. DOI: 10.1016/J.Bone.2010.04.257  0.356
2009 Guinea-Viniegra J, Zenz R, Scheuch H, Hnisz D, Holcmann M, Bakiri L, Schonthaler HB, Sibilia M, Wagner EF. TNFalpha shedding and epidermal inflammation are controlled by Jun proteins. Genes & Development. 23: 2663-74. PMID 19933155 DOI: 10.1101/Gad.543109  0.387
2009 Wagner EF, Nebreda AR. Signal integration by JNK and p38 MAPK pathways in cancer development. Nature Reviews. Cancer. 9: 537-49. PMID 19629069 DOI: 10.1038/Nrc2694  0.349
2009 Julien M, Khoshniat S, Lacreusette A, Gatius M, Bozec A, Wagner EF, Wittrant Y, Masson M, Weiss P, Beck L, Magne D, Guicheux J. Phosphate-dependent regulation of MGP in osteoblasts: role of ERK1/2 and Fra-1. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 24: 1856-68. PMID 19419315 DOI: 10.1359/Jbmr.090508  0.413
2009 Grigoriadis A, Kennedy M, Bozec A, Stenbeck G, Wagner E, Keller G. Directed differentiation of human embryonic stem cells and induced pluripotent stem cells to functional osteoclasts Bone. 44: S216. DOI: 10.1016/J.Bone.2009.03.051  0.32
2009 Takada Y, Irie N, Gresh L, Nakamura T, Kato S, Wagner E, Matsuo K. Late expression of c-Fos during osteoclast differentiation determines osteoclast survival and bone mass Bone. 44: S137. DOI: 10.1016/J.Bone.2009.01.301  0.343
2008 Hui L, Zatloukal K, Scheuch H, Stepniak E, Wagner EF. Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation. The Journal of Clinical Investigation. 118: 3943-53. PMID 19033664 DOI: 10.1172/Jci37156  0.38
2008 Yotova IY, Vlatkovic IM, Pauler FM, Warczok KE, Ambros PF, Oshimura M, Theussl HC, Gessler M, Wagner EF, Barlow DP. Identification of the human homolog of the imprinted mouse Air non-coding RNA. Genomics. 92: 464-73. PMID 18789384 DOI: 10.1016/J.Ygeno.2008.08.004  0.333
2008 Durchdewald M, Guinea-Viniegra J, Haag D, Riehl A, Lichter P, Hahn M, Wagner EF, Angel P, Hess J. Podoplanin is a novel fos target gene in skin carcinogenesis. Cancer Research. 68: 6877-83. PMID 18757399 DOI: 10.1158/0008-5472.Can-08-0299  0.396
2008 Gurzov EN, Ortis F, Bakiri L, Wagner EF, Eizirik DL. JunB Inhibits ER Stress and Apoptosis in Pancreatic Beta Cells. Plos One. 3: e3030. PMID 18716665 DOI: 10.1371/Journal.Pone.0003030  0.343
2008 Hasselblatt P, Gresh L, Kudo H, Guinea-Viniegra J, Wagner EF. The role of the transcription factor AP-1 in colitis-associated and beta-catenin-dependent intestinal tumorigenesis in mice. Oncogene. 27: 6102-9. PMID 18679426 DOI: 10.1038/Onc.2008.211  0.409
2008 Meixner A, Zenz R, Schonthaler HB, Kenner L, Scheuch H, Penninger JM, Wagner EF. Epidermal JunB represses G-CSF transcription and affects haematopoiesis and bone formation. Nature Cell Biology. 10: 1003-11. PMID 18641637 DOI: 10.1038/Ncb1761  0.375
2008 Ruiz-Bonilla V, Perdiguero E, Gresh L, Serrano AL, Zamora M, Sousa-Victor P, Jardí M, Wagner EF, Muñoz-Cánoves P. Efficient adult skeletal muscle regeneration in mice deficient in p38beta, p38gamma and p38delta MAP kinases. Cell Cycle (Georgetown, Tex.). 7: 2208-14. PMID 18641461 DOI: 10.4161/Cc.7.14.6273  0.321
2008 Eferl R, Hasselblatt P, Rath M, Popper H, Zenz R, Komnenovic V, Idarraga MH, Kenner L, Wagner EF. Development of pulmonary fibrosis through a pathway involving the transcription factor Fra-2/AP-1. Proceedings of the National Academy of Sciences of the United States of America. 105: 10525-30. PMID 18641127 DOI: 10.1073/Pnas.0801414105  0.383
2008 Gerlitz O, Wagner EF, Moreno E. When flies and mice develop cancer. Meeting on development and cancer. Embo Reports. 9: 730-4. PMID 18636085 DOI: 10.1038/Embor.2008.137  0.33
2008 Kolev V, Mandinova A, Guinea-Viniegra J, Hu B, Lefort K, Lambertini C, Neel V, Dummer R, Wagner EF, Dotto GP. EGFR signalling as a negative regulator of Notch1 gene transcription and function in proliferating keratinocytes and cancer. Nature Cell Biology. 10: 902-11. PMID 18604200 DOI: 10.1038/Ncb1750  0.392
2008 Bozec A, Bakiri L, Hoebertz A, Eferl R, Schilling AF, Komnenovic V, Scheuch H, Priemel M, Stewart CL, Amling M, Wagner EF. Osteoclast size is controlled by Fra-2 through LIF/LIF-receptor signalling and hypoxia. Nature. 454: 221-5. PMID 18548006 DOI: 10.1038/Nature07019  0.402
2008 Wolter S, Doerrie A, Weber A, Schneider H, Hoffmann E, von der Ohe J, Bakiri L, Wagner EF, Resch K, Kracht M. c-Jun controls histone modifications, NF-kappaB recruitment, and RNA polymerase II function to activate the ccl2 gene. Molecular and Cellular Biology. 28: 4407-23. PMID 18443042 DOI: 10.1128/Mcb.00535-07  0.403
2008 Hoffmann E, Ashouri J, Wolter S, Doerrie A, Dittrich-Breiholz O, Schneider H, Wagner EF, Troppmair J, Mackman N, Kracht M. Transcriptional regulation of EGR-1 by the interleukin-1-JNK-MKK7-c-Jun pathway. The Journal of Biological Chemistry. 283: 12120-8. PMID 18281687 DOI: 10.1074/Jbc.M800583200  0.359
2008 Kawamata A, Izu Y, Yokoyama H, Amagasa T, Wagner EF, Nakashima K, Ezura Y, Hayata T, Noda M. JunD suppresses bone formation and contributes to low bone mass induced by estrogen depletion. Journal of Cellular Biochemistry. 103: 1037-45. PMID 18240141 DOI: 10.1002/Jcb.21660  0.324
2008 Zenz R, Eferl R, Scheinecker C, Redlich K, Smolen J, Schonthaler HB, Kenner L, Tschachler E, Wagner EF. Activator protein 1 (Fos/Jun) functions in inflammatory bone and skin disease. Arthritis Research & Therapy. 10: 201. PMID 18226189 DOI: 10.1186/Ar2338  0.401
2008 Jiao X, Katiyar S, Liu M, Mueller SC, Lisanti MP, Li A, Pestell TG, Wu K, Ju X, Li Z, Wagner EF, Takeya T, Wang C, Pestell RG. Disruption of c-Jun reduces cellular migration and invasion through inhibition of c-Src and hyperactivation of ROCK II kinase. Molecular Biology of the Cell. 19: 1378-90. PMID 18216279 DOI: 10.1091/Mbc.E07-08-0753  0.395
2008 Wada T, Stepniak E, Hui L, Leibbrandt A, Katada T, Nishina H, Wagner EF, Penninger JM. Antagonistic control of cell fates by JNK and p38-MAPK signaling. Cell Death and Differentiation. 15: 89-93. PMID 17762881 DOI: 10.1038/Sj.Cdd.4402222  0.353
2008 Gurzov EN, Bakiri L, Alfaro JM, Wagner EF, Izquierdo M. Targeting c-Jun and JunB proteins as potential anticancer cell therapy. Oncogene. 27: 641-52. PMID 17667939 DOI: 10.1038/Sj.Onc.1210690  0.456
2007 Hui L, Bakiri L, Stepniak E, Wagner EF. p38alpha: a suppressor of cell proliferation and tumorigenesis. Cell Cycle (Georgetown, Tex.). 6: 2429-33. PMID 17957136 DOI: 10.4161/Cc.6.20.4774  0.436
2007 Hasselblatt P, Rath M, Komnenovic V, Zatloukal K, Wagner EF. Hepatocyte survival in acute hepatitis is due to c-Jun/AP-1-dependent expression of inducible nitric oxide synthase. Proceedings of the National Academy of Sciences of the United States of America. 104: 17105-10. PMID 17940019 DOI: 10.1073/Pnas.0706272104  0.406
2007 Hanahan D, Wagner EF, Palmiter RD. The origins of oncomice: a history of the first transgenic mice genetically engineered to develop cancer. Genes & Development. 21: 2258-70. PMID 17875663 DOI: 10.1101/Gad.1583307  0.32
2007 Eferl R, Zenz R, Theussl HC, Wagner EF. Simultaneous generation of fra-2 conditional and fra-2 knock-out mice. Genesis (New York, N.Y. : 2000). 45: 447-51. PMID 17607691 DOI: 10.1002/Dvg.20311  0.411
2007 Yamashita T, Yao Z, Li F, Zhang Q, Badell IR, Schwarz EM, Takeshita S, Wagner EF, Noda M, Matsuo K, Xing L, Boyce BF. NF-kappaB p50 and p52 regulate receptor activator of NF-kappaB ligand (RANKL) and tumor necrosis factor-induced osteoclast precursor differentiation by activating c-Fos and NFATc1. The Journal of Biological Chemistry. 282: 18245-53. PMID 17485464 DOI: 10.1074/Jbc.M610701200  0.393
2007 Hui L, Bakiri L, Mairhorfer A, Schweifer N, Haslinger C, Kenner L, Komnenovic V, Scheuch H, Beug H, Wagner EF. p38alpha suppresses normal and cancer cell proliferation by antagonizing the JNK-c-Jun pathway. Nature Genetics. 39: 741-9. PMID 17468757 DOI: 10.1038/Ng2033  0.458
2007 Vogel J, Weigand MA, Behrens A, Wagner EF, Schorpp-Kistner M, Zimmermann M, Schenkel J. Infarct volume after transient middle cerebral artery occlusion (MCAo) can be reduced by attenuation but not by inactivation of c-Jun action. Brain Research. 1151: 12-9. PMID 17428453 DOI: 10.1016/J.Brainres.2007.03.023  0.384
2007 Perdiguero E, Ruiz-Bonilla V, Gresh L, Hui L, Ballestar E, Sousa-Victor P, Baeza-Raja B, Jardí M, Bosch-Comas A, Esteller M, Caelles C, Serrano AL, Wagner EF, Muñoz-Cánoves P. Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferation. The Embo Journal. 26: 1245-56. PMID 17304211 DOI: 10.1038/Sj.Emboj.7601587  0.363
2007 Ott RG, Simma O, Kollmann K, Weisz E, Zebedin EM, Schorpp-Kistner M, Heller G, Zöchbauer S, Wagner EF, Freissmuth M, Sexl V. JunB is a gatekeeper for B-lymphoid leukemia. Oncogene. 26: 4863-71. PMID 17297445 DOI: 10.1038/Sj.Onc.1210285  0.424
2007 Bakiri L, Takada Y, Radolf M, Eferl R, Yaniv M, Wagner EF, Matsuo K. Role of heterodimerization of c-Fos and Fra1 proteins in osteoclast differentiation. Bone. 40: 867-75. PMID 17189721 DOI: 10.1016/J.Bone.2006.11.005  0.383
2007 Katiyar S, Jiao X, Wagner E, Lisanti MP, Pestell RG. Somatic excision demonstrates that c-Jun induces cellular migration and invasion through induction of stem cell factor Molecular and Cellular Biology. 27: 1356-1369. PMID 17145782 DOI: 10.1128/Mcb.01061-06  0.435
2006 Stepniak E, Ricci R, Eferl R, Sumara G, Sumara I, Rath M, Hui L, Wagner EF. c-Jun/AP-1 controls liver regeneration by repressing p53/p21 and p38 MAPK activity. Genes & Development. 20: 2306-14. PMID 16912279 DOI: 10.1101/Gad.390506  0.392
2006 Zenz R, Wagner EF. Jun signalling in the epidermis: From developmental defects to psoriasis and skin tumors. The International Journal of Biochemistry & Cell Biology. 38: 1043-9. PMID 16423552 DOI: 10.1016/J.Biocel.2005.11.011  0.426
2006 Bozec A, Hoebertz A, Schilling AF, Karreth F, Scheuch H, Priemel M, Amling M, Eferl R, Wagner EF. FRA-2 is a novel regulator of bone development affecting osteoclasts, osteoblasts and chondrocytes Bone. 38: 9. DOI: 10.1016/J.Bone.2006.01.070  0.308
2005 Wagner EF, Eferl R. Fos/AP-1 proteins in bone and the immune system. Immunological Reviews. 208: 126-40. PMID 16313345 DOI: 10.1111/J.0105-2896.2005.00332.X  0.368
2005 Asagiri M, Sato K, Usami T, Ochi S, Nishina H, Yoshida H, Morita I, Wagner EF, Mak TW, Serfling E, Takayanagi H. Autoamplification of NFATc1 expression determines its essential role in bone homeostasis. The Journal of Experimental Medicine. 202: 1261-9. PMID 16275763 DOI: 10.1084/Jem.20051150  0.447
2005 Zenz R, Eferl R, Kenner L, Florin L, Hummerich L, Mehic D, Scheuch H, Angel P, Tschachler E, Wagner EF. Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins. Nature. 437: 369-75. PMID 16163348 DOI: 10.1038/Nature03963  0.348
2005 Fu L, Patel MS, Bradley A, Wagner EF, Karsenty G. The molecular clock mediates leptin-regulated bone formation. Cell. 122: 803-15. PMID 16143109 DOI: 10.1016/J.Cell.2005.06.028  0.366
2005 Besirli CG, Wagner EF, Johnson EM. The limited role of NH2-terminal c-Jun phosphorylation in neuronal apoptosis: identification of the nuclear pore complex as a potential target of the JNK pathway. The Journal of Cell Biology. 170: 401-11. PMID 16061693 DOI: 10.1083/Jcb.200501138  0.324
2005 Terme M, Borg C, Guilhot F, Masurier C, Flament C, Wagner EF, Caillat-Zucman S, Bernheim A, Turhan AG, Caignard A, Zitvogel L. BCR/ABL promotes dendritic cell-mediated natural killer cell activation. Cancer Research. 65: 6409-17. PMID 16024645 DOI: 10.1158/0008-5472.Can-04-2675  0.375
2005 Ruocco MG, Maeda S, Park JM, Lawrence T, Hsu LC, Cao Y, Schett G, Wagner EF, Karin M. I{kappa}B kinase (IKK){beta}, but not IKK{alpha}, is a critical mediator of osteoclast survival and is required for inflammation-induced bone loss. The Journal of Experimental Medicine. 201: 1677-87. PMID 15897281 DOI: 10.1084/Jem.20042081  0.507
2005 Hayer S, Steiner G, Görtz B, Reiter E, Tohidast-Akrad M, Amling M, Hoffmann O, Redlich K, Zwerina J, Skriner K, Hilberg F, Wagner EF, Smolen JS, Schett G. CD44 is a determinant of inflammatory bone loss. The Journal of Experimental Medicine. 201: 903-14. PMID 15781582 DOI: 10.1084/Jem.20040852  0.343
2005 David JP, Mehic D, Bakiri L, Schilling AF, Mandic V, Priemel M, Idarraga MH, Reschke MO, Hoffmann O, Amling M, Wagner EF. Essential role of RSK2 in c-Fos-dependent osteosarcoma development. The Journal of Clinical Investigation. 115: 664-72. PMID 15719069 DOI: 10.1172/Jci22877  0.434
2005 Ameyar-Zazoua M, Wisniewska MB, Bakiri L, Wagner EF, Yaniv M, Weitzman JB. AP-1 dimers regulate transcription of the p14/p19ARF tumor suppressor gene. Oncogene. 24: 2298-306. PMID 15688012 DOI: 10.1038/Sj.Onc.1208424  0.405
2005 Brecht S, Kirchhof R, Chromik A, Willesen M, Nicolaus T, Raivich G, Wessig J, Waetzig V, Goetz M, Claussen M, Pearse D, Kuan CY, Vaudano E, Behrens A, Wagner E, et al. Specific pathophysiological functions of JNK isoforms in the brain. The European Journal of Neuroscience. 21: 363-77. PMID 15673436 DOI: 10.1111/J.1460-9568.2005.03857.X  0.351
2005 Ricci R, Eriksson U, Oudit GY, Eferl R, Akhmedov A, Sumara I, Sumara G, Kassiri Z, David JP, Bakiri L, Sasse B, Idarraga MH, Rath M, Kurz D, Theussl HC, ... ... Wagner EF, et al. Distinct functions of junD in cardiac hypertrophy and heart failure. Genes & Development. 19: 208-13. PMID 15655111 DOI: 10.1101/Gad.327005  0.321
2005 Mehic D, Bakiri L, Ghannadan M, Wagner EF, Tschachler E. Fos and jun proteins are specifically expressed during differentiation of human keratinocytes. The Journal of Investigative Dermatology. 124: 212-20. PMID 15654976 DOI: 10.1111/J.0022-202X.2004.23558.X  0.383
2005 Moriggl R, Sexl V, Kenner L, Duntsch C, Stangl K, Gingras S, Hoffmeyer A, Bauer A, Piekorz R, Wang D, Bunting KD, Wagner EF, Sonneck K, Valent P, Ihle JN, et al. Stat5 tetramer formation is associated with leukemogenesis. Cancer Cell. 7: 87-99. PMID 15652752 DOI: 10.1016/J.Ccr.2004.12.010  0.388
2005 Köller M, Hayer S, Redlich K, Ricci R, David JP, Steiner G, Smolen JS, Wagner EF, Schett G. JNK1 is not essential for TNF-mediated joint disease. Arthritis Research & Therapy. 7: R166-73. PMID 15642137 DOI: 10.1186/Ar1473  0.395
2004 Sabapathy K, Wagner EF. JNK2: a negative regulator of cellular proliferation. Cell Cycle (Georgetown, Tex.). 3: 1520-3. PMID 15611655 DOI: 10.4161/Cc.3.12.1315  0.463
2004 Ricci R, Sumara G, Sumara I, Rozenberg I, Kurrer M, Akhmedov A, Hersberger M, Eriksson U, Eberli FR, Becher B, Borén J, Chen M, Cybulsky MI, Moore KJ, Freeman MW, ... Wagner EF, et al. Requirement of JNK2 for scavenger receptor A-mediated foam cell formation in atherogenesis. Science (New York, N.Y.). 306: 1558-61. PMID 15567863 DOI: 10.1126/Science.1101909  0.403
2004 Gass P, Fleischmann A, Hvalby O, Jensen V, Zacher C, Strekalova T, Kvello A, Wagner EF, Sprengel R. Mice with a fra-1 knock-in into the c-fos locus show impaired spatial but regular contextual learning and normal LTP. Brain Research. Molecular Brain Research. 130: 16-22. PMID 15519672 DOI: 10.1016/J.Molbrainres.2004.07.004  0.348
2004 Karreth F, Hoebertz A, Scheuch H, Eferl R, Wagner EF. The AP1 transcription factor Fra2 is required for efficient cartilage development. Development (Cambridge, England). 131: 5717-25. PMID 15509771 DOI: 10.1242/Dev.01414  0.403
2004 Passegué E, Wagner EF, Weissman IL. JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells. Cell. 119: 431-43. PMID 15507213 DOI: 10.1016/J.Cell.2004.10.010  0.683
2004 Sabapathy K, Hochedlinger K, Nam SY, Bauer A, Karin M, Wagner EF. Distinct roles for JNK1 and JNK2 in regulating JNK activity and c-Jun-dependent cell proliferation. Molecular Cell. 15: 713-25. PMID 15350216 DOI: 10.1016/J.Molcel.2004.08.028  0.545
2004 Kubovcakova L, Tybitanclova K, Sabban EL, Majzoub J, Zorad S, Vietor I, Wagner EF, Krizanova O, Kvetnansky R. Catecholamine synthesizing enzymes and their modulation by immobilization stress in knockout mice. Annals of the New York Academy of Sciences. 1018: 458-65. PMID 15240402 DOI: 10.1196/Annals.1296.056  0.375
2004 Raivich G, Bohatschek M, Da Costa C, Iwata O, Galiano M, Hristova M, Nateri AS, Makwana M, Riera-Sans L, Wolfer DP, Lipp HP, Aguzzi A, Wagner EF, Behrens A. The AP-1 transcription factor c-Jun is required for efficient axonal regeneration. Neuron. 43: 57-67. PMID 15233917 DOI: 10.1016/J.Neuron.2004.06.005  0.352
2004 Eferl R, Hoebertz A, Schilling AF, Rath M, Karreth F, Kenner L, Amling M, Wagner EF. The Fos-related antigen Fra-1 is an activator of bone matrix formation. The Embo Journal. 23: 2789-99. PMID 15229648 DOI: 10.1038/Sj.Emboj.7600282  0.371
2004 Rossiter H, Barresi C, Pammer J, Rendl M, Haigh J, Wagner EF, Tschachler E. Loss of vascular endothelial growth factor a activity in murine epidermal keratinocytes delays wound healing and inhibits tumor formation. Cancer Research. 64: 3508-16. PMID 15150105 DOI: 10.1158/0008-5472.Can-03-2581  0.325
2004 Terme M, Tomasello E, Maruyama K, Crépineau F, Chaput N, Flament C, Marolleau JP, Angevin E, Wagner EF, Salomon B, Lemonnier FA, Wakasugi H, Colonna M, Vivier E, Zitvogel L. IL-4 confers NK stimulatory capacity to murine dendritic cells: a signaling pathway involving KARAP/DAP12-triggering receptor expressed on myeloid cell 2 molecules. Journal of Immunology (Baltimore, Md. : 1950). 172: 5957-66. PMID 15128777 DOI: 10.4049/Jimmunol.172.10.5957  0.349
2004 Roschger P, Matsuo K, Misof BM, Tesch W, Jochum W, Wagner EF, Fratzl P, Klaushofer K. Normal mineralization and nanostructure of sclerotic bone in mice overexpressing Fra-1 Bone. 34: 776-782. PMID 15121008 DOI: 10.1016/J.Bone.2004.01.004  0.362
2004 Matsuo K, Galson DL, Zhao C, Peng L, Laplace C, Wang KZ, Bachler MA, Amano H, Aburatani H, Ishikawa H, Wagner EF. Nuclear factor of activated T-cells (NFAT) rescues osteoclastogenesis in precursors lacking c-Fos. The Journal of Biological Chemistry. 279: 26475-80. PMID 15073183 DOI: 10.1074/Jbc.M313973200  0.456
2004 Wada T, Joza N, Cheng HY, Sasaki T, Kozieradzki I, Bachmaier K, Katada T, Schreiber M, Wagner EF, Nishina H, Penninger JM. MKK7 couples stress signalling to G2/M cell-cycle progression and cellular senescence. Nature Cell Biology. 6: 215-26. PMID 15039780 DOI: 10.1038/Ncb1098  0.38
2004 Meixner A, Karreth F, Kenner L, Wagner EF. JunD regulates lymphocyte proliferation and T helper cell cytokine expression Embo Journal. 23: 1325-1335. PMID 15029240 DOI: 10.1038/Sj.Emboj.7600133  0.352
2004 Kenner L, Hoebertz A, Beil FT, Beil T, Keon N, Karreth F, Eferl R, Scheuch H, Szremska A, Amling M, Schorpp-Kistner M, Angel P, Wagner EF. Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects. The Journal of Cell Biology. 164: 613-23. PMID 14769860 DOI: 10.1083/Jcb.200308155  0.457
2004 Eferl R, Wagner EF. AP-1: a double-edged sword in tumorigenesis. Nature Reviews. Cancer. 3: 859-68. PMID 14668816 DOI: 10.1038/Nrc1209  0.328
2004 Passegue E, Wagner EF, Weissman IL. Junb Regulates Hematopoietic Stem Cell Numbers in Normal and Leukemic Mice. Blood. 104: 560-560. DOI: 10.1182/Blood.V104.11.560.560  0.55
2003 Fleischmann A, Jochum W, Eferl R, Witowsky J, Wagner EF. Rhabdomyosarcoma development in mice lacking Trp53 and Fos: Tumor suppression by the Fos protooncogene Cancer Cell. 4: 477-482. PMID 14706339 DOI: 10.1016/S1535-6108(03)00280-0  0.427
2003 Fleischmann A, Hvalby O, Jensen V, Strekalova T, Zacher C, Layer LE, Kvello A, Reschke M, Spanagel R, Sprengel R, Wagner EF, Gass P. Impaired long-term memory and NR2A-type NMDA receptor-dependent synaptic plasticity in mice lacking c-Fos in the CNS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9116-22. PMID 14534245 DOI: 10.1523/Jneurosci.23-27-09116.2003  0.34
2003 Wagner EF, Matsuo K. Signalling in osteoclasts and the role of Fos/AP1 proteins. Annals of the Rheumatic Diseases. ii83-5. PMID 14532157 DOI: 10.1136/Ard.62.Suppl_2.Ii83  0.421
2003 Sibilia M, Wagner B, Hoebertz A, Elliott C, Marino S, Jochum W, Wagner EF. Mice humanised for the EGF receptor display hypomorphic phenotypes in skin, bone and heart. Development (Cambridge, England). 130: 4515-25. PMID 12925580 DOI: 10.1242/Dev.00664  0.38
2003 Szremska AP, Kenner L, Weisz E, Ott RG, Passegué E, Artwohl M, Freissmuth M, Stoxreiter R, Theussl HC, Parzer SB, Moriggl R, Wagner EF, Sexl V. JunB inhibits proliferation and transformation in B-lymphoid cells. Blood. 102: 4159-65. PMID 12907453 DOI: 10.1182/Blood-2003-03-0915  0.665
2003 Weiss C, Schneider S, Wagner EF, Zhang X, Seto E, Bohmann D. JNK phosphorylation relieves HDAC3-dependent suppression of the transcriptional activity of c-Jun. The Embo Journal. 22: 3686-95. PMID 12853483 DOI: 10.1093/Emboj/Cdg364  0.371
2003 Zenz R, Scheuch H, Martin P, Frank C, Eferl R, Kenner L, Sibilia M, Wagner EF. c-Jun regulates eyelid closure and skin tumor development through EGFR signaling Developmental Cell. 4: 879-889. PMID 12791272 DOI: 10.1016/S1534-5807(03)00161-8  0.384
2003 Schausberger E, Eferl R, Parzefall W, Chabicovsky M, Breit P, Wagner EF, Schulte-Hermann R, Grasl-Kraupp B, Chabikovsky M. Induction of DNA synthesis in primary mouse hepatocytes is associated with nuclear pro-transforming growth factor alpha and erbb-1 and is independent of c-jun. Carcinogenesis. 24: 835-41. PMID 12771026 DOI: 10.1093/Carcin/Bgg027  0.36
2003 Weston CR, Balmanno K, Chalmers C, Hadfield K, Molton SA, Ley R, Wagner EF, Cook SJ. Activation of ERK1/2 by deltaRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways. Oncogene. 22: 1281-93. PMID 12618753 DOI: 10.1038/Sj.Onc.1206261  0.356
2003 Eferl R, Ricci R, Kenner L, Zenz R, David JP, Rath M, Wagner EF. Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53. Cell. 112: 181-92. PMID 12553907 DOI: 10.1016/S0092-8674(03)00042-4  0.366
2003 Takayanagi H, Kim S, Koga T, Nishina H, Isshiki M, Yoshida H, Saiura A, Isobe M, Yokochi T, Inoue J, Wagner EF, Mak TW, Kodama T, Taniguchi T. Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts. Developmental Cell. 3: 889-901. PMID 12479813 DOI: 10.1016/S1534-5807(02)00369-6  0.396
2003 Behrens A, Haigh J, Mechta-Grigoriou F, Nagy A, Yaniv M, Wagner EF. Impaired intervertebral disc formation in the absence of Jun. Development (Cambridge, England). 130: 103-9. PMID 12441295 DOI: 10.1242/Dev.00186  0.391
2003 Wagner E, Eferl R, Hoebertz A, Kenner L, Matsuo K. Bone cell differentiation and the role of Fos/AP-1 proteins Arthritis Research & Therapy. 5: 49-49. DOI: 10.1186/Ar850  0.448
2002 Redlich K, Hayer S, Ricci R, David J, Tohidast-Akrad M, Kollias G, Steiner G, Smolen JS, Wagner EF, Schett G. Osteoclasts are essential for TNF-α–mediated joint destruction Journal of Clinical Investigation. 110: 1419-1427. PMID 12438440 DOI: 10.1172/Jci15582  0.374
2002 Verrecchia F, Tacheau C, Wagner EF, Mauviel A. A central role for the JNK pathway in mediating the antagonistic activity of pro-inflammatory cytokines against transforming growth factor-beta-driven SMAD3/4-specific gene expression. The Journal of Biological Chemistry. 278: 1585-93. PMID 12426318 DOI: 10.1074/Jbc.M206927200  0.35
2002 Verrecchia F, Wagner EF, Mauviel A. Distinct involvement of the Jun-N-terminal kinase and NF-kappaB pathways in the repression of the human COL1A2 gene by TNF-alpha. Embo Reports. 3: 1069-74. PMID 12393755 DOI: 10.1093/Embo-Reports/Kvf219  0.314
2002 Wagner EF. Functions of AP1 (Fos/Jun) in bone development. Annals of the Rheumatic Diseases. ii40-2. PMID 12379619 DOI: 10.1136/Ard.61.Suppl_2.Ii40  0.473
2002 David J, Sabapathy K, Hoffmann O, Idarraga MH, Wagner EF. JNK1 modulates osteoclastogenesis through both c-Jun phosphorylation-dependent and -independent mechanisms Journal of Cell Science. 115: 4317-4325. PMID 12376563 DOI: 10.1242/Jcs.00082  0.409
2002 Hidding U, Mielke K, Waetzig V, Brecht S, Hanisch U, Behrens A, Wagner E, Herdegen T. The c-Jun N-terminal kinases in cerebral microglia: immunological functions in the brain. Biochemical Pharmacology. 64: 781-788. PMID 12213570 DOI: 10.1016/S0006-2952(02)01139-5  0.37
2002 Bakiri L, Matsuo K, Wisniewska M, Wagner EF, Yaniv M. Promoter specificity and biological activity of tethered AP-1 dimers. Molecular and Cellular Biology. 22: 4952-64. PMID 12052899 DOI: 10.1128/Mcb.22.13.4952-4964.2002  0.397
2002 Yoshida K, Behrens A, Le-Niculescu H, Wagner EF, Harada T, Imaki J, Ohno S, Karin M. Amino-terminal phosphorylation of c-Jun regulates apoptosis in the retinal ganglion cells by optic nerve transection. Investigative Ophthalmology & Visual Science. 43: 1631-5. PMID 11980884  0.389
2002 Karsenty G, Wagner EF. Reaching a genetic and molecular understanding of skeletal development. Developmental Cell. 2: 389-406. PMID 11970890 DOI: 10.1016/S1534-5807(02)00157-0  0.3
2002 Takayanagi H, Kim S, Matsuo K, Suzuki H, Suzuki T, Sato K, Yokochi T, Oda H, Nakamura K, Ida N, Wagner EF, Taniguchi T. RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-beta. Nature. 416: 744-9. PMID 11961557 DOI: 10.1038/416744A  0.379
2002 Wenzel A, Iseli HP, Fleischmann A, Hafezi F, Grimm C, Wagner EF, Remé CE. Fra-1 substitutes for c-Fos in AP-1-mediated signal transduction in retinal apoptosis. Journal of Neurochemistry. 80: 1089-94. PMID 11953459 DOI: 10.1046/J.0022-3042.2002.00807.X  0.396
2002 Hochedlinger K, Wagner EF, Sabapathy K. Differential effects of JNK1 and JNK2 on signal specific induction of apoptosis. Oncogene. 21: 2441-5. PMID 11948429 DOI: 10.1038/Sj.Onc.1205348  0.383
2002 Behrens A, Sibilia M, David JP, Möhle-Steinlein U, Tronche F, Schütz G, Wagner EF. Impaired postnatal hepatocyte proliferation and liver regeneration in mice lacking c-jun in the liver. The Embo Journal. 21: 1782-90. PMID 11927562 DOI: 10.1093/Emboj/21.7.1782  0.415
2002 Passegué E, Jochum W, Behrens A, Ricci R, Wagner EF. JunB can substitute for Jun in mouse development and cell proliferation. Nature Genetics. 30: 158-66. PMID 11818961 DOI: 10.1038/Ng790  0.67
2002 Redlich K, Hayer S, Ricci R, David J, Tohidast-Akrad M, Zwerina J, Kollias G, Steiner G, Smolen J, Wagner E, Schett G. Arthritis Research. 4: 10. DOI: 10.1186/Ar434  0.398
2001 Tuckermann JP, Vallon R, Gack S, Grigoriadis AE, Porte D, Lutz A, Wagner EF, Schmidt J, Angel P. Expression of collagenase-3 (MMP-13) in c-fos-induced osteosarcomas and chondrosarcomas is restricted to a subset of cells of the osteo-/chondrogenic lineage. Differentiation. 69: 49-57. PMID 11776394 DOI: 10.1046/J.1432-0436.2001.690105.X  0.403
2001 Stoll SW, Kansra S, Peshick S, Fry DW, Leopold WR, Wiesen JF, Sibilia M, Zhang T, Werb Z, Derynck R, Wagner EF, Elder JT. Differential utilization and localization of ErbB receptor tyrosine kinases in skin compared to normal and malignant keratinocytes. Neoplasia (New York, N.Y.). 3: 339-50. PMID 11571634 DOI: 10.1038/Sj.Neo.7900170  0.339
2001 Wagner EF, Karsenty G. Genetic control of skeletal development. Current Opinion in Genetics & Development. 11: 527-32. PMID 11532394 DOI: 10.1016/S0959-437X(00)00228-8  0.341
2001 Grimm C, Wenzel A, Behrens A, Hafezi F, Wagner EF, Remé CE. AP-1 mediated retinal photoreceptor apoptosis is independent of N-terminal phosphorylation of c-Jun Cell Death & Differentiation. 8: 859-867. PMID 11526439 DOI: 10.1038/Sj.Cdd.4400871  0.402
2001 Jochum W, Passegué E, Wagner EF. AP-1 in mouse development and tumorigenesis. Oncogene. 20: 2401-12. PMID 11402336 DOI: 10.1038/Sj.Onc.1204389  0.669
2001 Wagner EF. AP-1--Introductory remarks. Oncogene. 20: 2334-5. PMID 11402330 DOI: 10.1038/Sj.Onc.1204416  0.362
2001 Mikula M, Schreiber M, Husak Z, Kucerova L, Rüth J, Wieser R, Zatloukal K, Beug H, Wagner EF, Baccarini M. Embryonic lethality and fetal liver apoptosis in mice lacking the c-raf-1 gene. The Embo Journal. 20: 1952-62. PMID 11296228 DOI: 10.1093/Emboj/20.8.1952  0.446
2001 Behrens A, Sabapathy K, Graef I, Cleary M, Crabtree GR, Wagner EF. Jun N-terminal kinase 2 modulates thymocyte apoptosis and T cell activation through c-Jun and nuclear factor of activated T cell (NF-AT). Proceedings of the National Academy of Sciences of the United States of America. 98: 1769-74. PMID 11172026 DOI: 10.1073/Pnas.98.4.1769  0.436
2001 Passegué E, Jochum W, Schorpp-Kistner M, Möhle-Steinlein U, Wagner EF. Chronic myeloid leukemia with increased granulocyte progenitors in mice lacking junB expression in the myeloid lineage. Cell. 104: 21-32. PMID 11163237 DOI: 10.1016/S0092-8674(01)00188-X  0.693
2001 Jesenberger V, Procyk KJ, Rüth J, Schreiber M, Theussl HC, Wagner EF, Baccarini M. Protective role of Raf-1 in Salmonella-induced macrophage apoptosis. The Journal of Experimental Medicine. 193: 353-64. PMID 11157055 DOI: 10.1084/Jem.193.3.353  0.344
2001 Sabapathy K, Kallunki T, David JP, Graef I, Karin M, Wagner EF. c-Jun NH2-terminal kinase (JNK)1 and JNK2 have similar and stage-dependent roles in regulating T cell apoptosis and proliferation. The Journal of Experimental Medicine. 193: 317-28. PMID 11157052 DOI: 10.1084/Jem.193.3.317  0.53
2001 Shaulian E, Schreiber M, Piu F, Beeche M, Wagner EF, Karin M. The mammalian UV response: c-Jun induction is required for exit from p53-imposed growth arrest. Cell. 103: 897-907. PMID 11136975 DOI: 10.1016/S0092-8674(00)00193-8  0.531
2000 Heumann R, Goemans C, Bartsch D, Lingenhöhl K, Waldmeier PC, Hengerer B, Allegrini PR, Schellander K, Wagner EF, Arendt T, Kamdem RH, Obst-Pernberg K, Narz F, Wahle P, Berns H. Transgenic activation of Ras in neurons promotes hypertrophy and protects from lesion-induced degeneration Journal of Cell Biology. 151: 1537-1548. PMID 11134081 DOI: 10.1083/Jcb.151.7.1537  0.31
2000 Jochum W, David JP, Elliot C, Wutz A, Plenk HJ, Matsuo K, Wagner EF. Erratum: Increased bone formation and osteosclerosis in mice overexpressing the transcription factor Fra-1 (Nature Medicine (2000) 6 (980-984)) Nature Medicine. 6. PMID 11100131 DOI: 10.1038/82242  0.371
2000 Fleischmann A, Hafezi F, Elliott C, Remé CE, Rüther U, Wagner EF. Fra-1 replaces c-Fos-dependent functions in mice. Genes & Development. 14: 2695-700. PMID 11069886 DOI: 10.1101/Gad.187900  0.451
2000 Jochum W, David JP, Elliott C, Wutz A, Plenk H, Matsuo K, Wagner EF. Increased bone formation and osteosclerosis in mice overexpressing the transcription factor Fra-1. Nature Medicine. 6: 980-4. PMID 10973316 DOI: 10.1038/79676  0.394
2000 Sibilia M, Fleischmann A, Behrens A, Stingl L, Carroll J, Watt FM, Schlessinger J, Wagner EF. The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development. Cell. 102: 211-20. PMID 10943841 DOI: 10.1016/S0092-8674(00)00026-X  0.345
2000 Lean JM, Matsuo K, Fox SW, Fuller K, Gibson FM, Draycott G, Wani MR, Bayley KE, Wong BR, Choi Y, Wagner EF, Chambers TJ. Osteoclast lineage commitment of bone marrow precursors through expression of membrane-bound TRANCE Bone. 27: 29-40. PMID 10865206 DOI: 10.1016/S8756-3282(00)00306-9  0.39
2000 Passegué E, Wagner EF. JunB suppresses cell proliferation by transcriptional activation of p16(INK4a) expression. The Embo Journal. 19: 2969-79. PMID 10856241 DOI: 10.1093/Emboj/19.12.2969  0.65
2000 Behrens A, Jochum W, Sibilia M, Wagner EF. Oncogenic transformation by ras and fos is mediated by c-Jun N-terminal phosphorylation Oncogene. 19: 2657-2663. PMID 10851065 DOI: 10.1038/Sj.Onc.1203603  0.42
2000 Matsuo K, Owens JM, Tonko M, Elliott C, Chambers TJ, Wagner EF. Fosl1 is a transcriptional target of c-Fos during osteoclast differentiation. Nature Genetics. 24: 184-7. PMID 10655067 DOI: 10.1038/72855  0.44
2000 Kolbus A, Herr I, Schreiber M, Debatin KM, Wagner EF, Angel P. c-Jun-dependent CD95-L expression is a rate-limiting step in the induction of apoptosis by alkylating agents. Molecular and Cellular Biology. 20: 575-82. PMID 10611236 DOI: 10.1128/Mcb.20.2.575-582.2000  0.352
2000 Sabapathy K, Jochum W, Hochedlinger K, Chang L, Karin M, Wagner EF. Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2. Mechanisms of Development. 89: 115-24. PMID 10559486 DOI: 10.1016/S0925-4773(99)00213-0  0.506
2000 Schreiber M, Piu F, Kolbus A, Szabowski A, Möhle-Steinlein U, Tian J, Karin M, Angel P, Wagner E. Negative regulation of p53 expression is an essential, rate-limiting function of Jun in the control of cell cycle progression Breast Cancer Research. 2. DOI: 10.1186/Bcr167  0.494
2000 Tagaya H, Kunisada T, Yamazaki H, Yamane T, Tokuhisa T, Wagner EF, Sudo T, Shultz LD, Hayashi S. Intramedullary and extramedullary B lymphopoiesis in osteopetrotic mice Blood. 95: 3363-3370. DOI: 10.1182/Blood.V95.11.3363  0.365
1999 Beedles KE, Sharpe PT, Wagner EF, Grigoriadis AE. A putative role for c-Fos in the pathophysiology of Paget's disease. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 21-8. PMID 10510209 DOI: 10.1002/Jbmr.5650140206  0.425
1999 Mühlner U, Möhle-Steinlein U, Wizigmann-Voos S, Christofori G, Risau W, Wagner EF. Formation of transformed endothelial cells in the absence of VEGFR-2/Flk-1 by Polyoma middle T oncogene. Oncogene. 18: 4200-10. PMID 10435633 DOI: 10.1038/Sj.Onc.1203014  0.357
1999 Matsuo K, Jochum W, Owens JM, Chambers TJ, Wagner EF. Function of Fos proteins in bone cell differentiation. Bone. 25: 141. PMID 10423040 DOI: 10.1016/S8756-3282(99)00120-9  0.496
1999 De Graeve F, Bahr A, Sabapathy KT, Hauss C, Wagner EF, Kedinger C, Chatton B. Role of the ATFa/JNK2 complex in Jun activation. Oncogene. 18: 3491-500. PMID 10376527 DOI: 10.1038/Sj.Onc.1202723  0.302
1999 Eferl R, Sibilia M, Hilberg F, Fuchsbichler A, Kufferath I, Guertl B, Zenz R, Wagner EF, Zatloukal K. Functions of c-Jun in liver and heart development. The Journal of Cell Biology. 145: 1049-61. PMID 10352021 DOI: 10.1083/Jcb.145.5.1049  0.435
1999 Owens JM, Matsuo K, Nicholson GC, Wagner EF, Chambers TJ. Fra-1 potentiates osteoclastic differentiation in osteoclast-macrophage precursor cell lines. Journal of Cellular Physiology. 179: 170-8. PMID 10199556 DOI: 10.1002/(Sici)1097-4652(199905)179:2<170::Aid-Jcp7>3.0.Co;2-K  0.423
1999 Burkart V, Wang ZQ, Radons J, Heller B, Herceg Z, Stingl L, Wagner EF, Kolb H. Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin. Nature Medicine. 5: 314-9. PMID 10086388 DOI: 10.1038/6535  0.342
1999 Behrens A, Sibilia M, Wagner EF. Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation. Nature Genetics. 21: 326-9. PMID 10080190 DOI: 10.1038/6854  0.404
1999 Tropepe V, Sibilia M, Ciruna BG, Rossant J, Wagner EF, van der Kooy D. Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon. Developmental Biology. 208: 166-88. PMID 10075850 DOI: 10.1006/Dbio.1998.9192  0.332
1999 Schreiber M, Kolbus A, Piu F, Szabowski A, Möhle-Steinlein U, Tian J, Karin M, Angel P, Wagner EF. Control of cell cycle progression by c-Jun is p53 dependent. Genes & Development. 13: 607-19. PMID 10072388 DOI: 10.1101/Gad.13.5.607  0.554
1999 Schorpp-Kistner M, Wang ZQ, Angel P, Wagner EF. JunB is essential for mammalian placentation. The Embo Journal. 18: 934-48. PMID 10022836 DOI: 10.1093/Emboj/18.4.934  0.368
1999 Sabapathy K, Hu Y, Kallunki T, Schreiber M, David JP, Jochum W, Wagner EF, Karin M. JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development. Current Biology : Cb. 9: 116-25. PMID 10021384 DOI: 10.1016/S0960-9822(99)80065-7  0.51
1998 Sibilia M, Steinbach JP, Stingl L, Aguzzi A, Wagner EF. A strain-independent postnatal neurodegeneration in mice lacking the EGF receptor. The Embo Journal. 17: 719-31. PMID 9450997 DOI: 10.1093/Emboj/17.3.719  0.363
1998 Olmsted EA, Gannon FH, Wang Z, Grigoriadis AE, Wagner EF, Zasloff MA, Shore EM, Kaplan FS. Embryonic Overexpression of the c-Fos Protooncogene Clinical Orthopaedics and Related Research. 346: 81???94. DOI: 10.1097/00003086-199801000-00013  0.419
1997 Morrison C, Smith GC, Stingl L, Jackson SP, Wagner EF, Wang ZQ. Genetic interaction between PARP and DNA-PK in V(D)J recombination and tumorigenesis. Nature Genetics. 17: 479-82. PMID 9398855 DOI: 10.1038/Ng1297-479  0.338
1997 Wutz A, Smrzka OW, Schweifer N, Schellander K, Wagner EF, Barlow DP. Imprinted expression of the Igf2r gene depends on an intronic CpG island. Nature. 389: 745-9. PMID 9338788 DOI: 10.1038/39631  0.313
1997 Sabapathy K, Klemm M, Jaenisch R, Wagner EF. Regulation of ES cell differentiation by functional and conformational modulation of p53. The Embo Journal. 16: 6217-29. PMID 9321401 DOI: 10.1093/Emboj/16.20.6217  0.541
1997 Wang ZQ, Stingl L, Morrison C, Jantsch M, Los M, Schulze-Osthoff K, Wagner EF. PARP is important for genomic stability but dispensable in apoptosis. Genes & Development. 11: 2347-58. PMID 9308963 DOI: 10.1101/Gad.11.18.2347  0.389
1997 Schreiber M, Poirier C, Franchi A, Kurzbauer R, Guenet JL, Carle GF, Wagner EF. Structure and chromosomal assignment of the mouse fra-1 gene, and its exclusion as a candidate gene for oc (osteosclerosis). Oncogene. 15: 1171-8. PMID 9294610 DOI: 10.1038/Sj.Onc.1201460  0.358
1997 Agarwal ML, Agarwal A, Taylor WR, Wang ZQ, Wagner EF, Stark GR. Defective induction but normal activation and function of p53 in mouse cells lacking poly-ADP-ribose polymerase Oncogene. 15: 1035-1041. PMID 9285557 DOI: 10.1038/Sj.Onc.1201274  0.377
1997 Wang Z, Kiefer F, Urbánek P, Wagner EF. Generation of completely embryonic stem cell-derived mutant mice using tetraploid blastocyst injection Mechanisms of Development. 62: 137-145. PMID 9152006 DOI: 10.1016/S0925-4773(97)00655-2  0.408
1997 Sabapathy KT, Pepper MS, Kiefer F, Möhle-Steinlein U, Tacchini-Cottier F, Fetka I, Breier G, Risau W, Carmeliet P, Montesano R, Wagner EF. Polyoma middle T-induced vascular tumor formation: the role of the plasminogen activator/plasmin system. The Journal of Cell Biology. 137: 953-63. PMID 9151696 DOI: 10.1083/Jcb.137.4.953  0.355
1997 Hafezi F, Steinbach JP, Marti A, Munz K, Wang ZQ, Wagner EF, Aguzzi A, Remé CE. The absence of c-fos prevents light-induced apoptotic cell death of photoreceptors in retinal degeneration in vivo. Nature Medicine. 3: 346-9. PMID 9055866 DOI: 10.1038/Nm0397-346  0.348
1997 Lijnen HR, Wagner EF, Collen D. Plasminogen-dependent and -independent Proteolytic Activity of Murine Endothelioma Cells with Targeted Inactivation of Fibrinolytic Genes Thrombosis and Haemostasis. 77: 362-367. DOI: 10.1055/S-0038-1655969  0.326
1996 Schorpp M, Jäger R, Schellander K, Schenkel J, Wagner EF, Weiher H, Angel P. The human ubiquitin C promoter directs high ubiquitous expression of transgenes in mice. Nucleic Acids Research. 24: 1787-8. PMID 8650001 DOI: 10.1093/Nar/24.9.1787  0.416
1996 Grigoriadis AE, Wang ZQ, Wagner EF. Fos and bone cell development: lessons from a nuclear oncogene. Trends in Genetics : Tig. 11: 436-41. PMID 8578600 DOI: 10.1016/S0168-9525(00)89142-8  0.409
1996 Volpe MAV, Sibilia M, Wagner EF, Nielsen HC. EMBRYONIC LUNG BRANCHING MORPHOGENESIS, CELL PROLIFERATION, AND DIFFERENTIATION ARE ALTERED IN EPIDERMAL GROWTH FACTOR RECEPTOR (EGF-R) -/- TRANSGENIC 129/SV × C57BL/6 MICE. • 406 Pediatric Research. 39: 70-70. DOI: 10.1203/00006450-199604001-00426  0.349
1995 Urbánek P, Wang ZQ, Fetka I, Wagner EF, Busslinger M. Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP. Cell. 79: 901-12. PMID 8001127 DOI: 10.1016/0092-8674(94)90079-5  0.351
1995 Chen J, Stewart V, Spyrou G, Hilberg F, Wagner EF, Alt FW. Generation of normal T and B lymphocytes by c-jun deficient embryonic stem cells. Immunity. 1: 65-72. PMID 7889400 DOI: 10.1016/1074-7613(94)90010-8  0.426
1995 Heller B, Wang Z, Wagner EF, Radons J, Burkle A, Fehsel K, Burkart V, Kolb H. Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells Journal of Biological Chemistry. 270: 11176-11180. PMID 7744749 DOI: 10.1074/Jbc.270.19.11176  0.362
1995 Wang ZQ, Auer B, Stingl L, Berghammer H, Haidacher D, Schweiger M, Wagner EF. Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease. Genes & Development. 9: 509-20. PMID 7698643 DOI: 10.1101/Gad.9.5.509  0.383
1995 Sibilia M, Wagner EF. Strain-dependent epithelial defects in mice lacking the EGF receptor Science. 269: 234-238. PMID 7618085 DOI: 10.1126/Science.7618085  0.381
1995 Auer B, Flick K, Wang ZQ, Haidacher D, Jäger S, Berghammer H, Kofler B, Schweiger M, Wagner EF. On the biological role of the nuclear polymerizing NAD+: protein(ADP-ribosyl) transferase (ADPRT): ADPRT from Dictyostelium discoideum and inactivation of the ADPRT gene in the mouse. Biochimie. 77: 444-9. PMID 7578427 DOI: 10.1016/0300-9084(96)88158-2  0.382
1995 WAGNER E, WANG Z. Transgenic mice for the analysis of gene function Pharmacological Research. 31: 19-19. DOI: 10.1016/1043-6618(95)86336-2  0.343
1995 Schreiber M, Baumann B, Cotten M, Angel P, Wagner EF. Fos is an essential component of the mammalian UV response. The Embo Journal. 14: 5338-5349. DOI: 10.1002/J.1460-2075.1995.Tb00218.X  0.411
1994 Okada S, Wang ZQ, Grigoriadis AE, Wagner EF, von Rüden T. Mice lacking c-fos have normal hematopoietic stem cells but exhibit altered B-cell differentiation due to an impaired bone marrow environment. Molecular and Cellular Biology. 14: 382-90. PMID 8264605 DOI: 10.1128/Mcb.14.1.382  0.434
1994 Wang ZQ, Fung MR, Barlow DP, Wagner EF. Regulation of embryonic growth and lysosomal targeting by the imprinted Igf2/Mpr gene. Nature. 372: 464-7. PMID 7984240 DOI: 10.1038/372464A0  0.357
1994 Kiefer F, Anhauser I, Soriano P, Aguzzi A, Courtneidge SA, Wagner EF. Endothelial cell transformation by polyomavirus middle T antigen in mice lacking Src-related kinases Current Biology. 4: 100-109. PMID 7953508 DOI: 10.1016/S0960-9822(94)00025-4  0.392
1994 Grigoriadis AE, Wang Z, Cecchini MG, Hofstetter W, Felix R, Fleisch HA, Wagner EF. c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling. Science. 266: 443-448. PMID 7939685 DOI: 10.1126/Science.7939685  0.388
1994 Kiefer F, Courtneidge SA, Wagner EF. Oncogenic properties of the middle T antigens of polyomaviruses Advances in Cancer Research. 64: 125-157. PMID 7879657 DOI: 10.1016/S0065-230X(08)60837-4  0.343
1994 Magyar JP, Bartsch U, Wang ZQ, Howells N, Aguzzi A, Wagner EF, Schachner M. Degeneration of neural cells in the central nervous system of mice deficient in the gene for the adhesion molecule on Glia, the beta 2 subunit of murine Na,K-ATPase. The Journal of Cell Biology. 127: 835-45. PMID 7525597 DOI: 10.1083/Jcb.127.3.835  0.305
1994 Wang Z, Stingl L, Auer B, Schweiger M, Wagner EF. Epidermal hyperplasia in mice lacking the NAD+:ADP-ribosyl-transferase (ADPRT) gene Journal of Investigative Dermatology. 103: 414. DOI: 10.5555/Uri:Pii:0022202X9492287X  0.346
1994 Gottlieb E, Haffner R, Rüden Tv, Wagner EF, Oren M. Down-regulation of wild-type p53 activity interferes with apoptosis of IL-3-dependent hematopoietic cells following IL-3 withdrawal. The Embo Journal. 13: 1368-1374. DOI: 10.1002/J.1460-2075.1994.Tb06390.X  0.317
1993 Hilberg F, Aguzzi A, Howells N, Wagner EF. c-jun is essential for normal mouse development and hepatogenesis. Nature. 365: 179-81. PMID 8371760 DOI: 10.1038/365179A0  0.461
1993 Grigoriadis AE, Schellander K, Wang ZQ, Wagner EF. Osteoblasts are target cells for transformation in c-fos transgenic mice. The Journal of Cell Biology. 122: 685-701. PMID 8335693 DOI: 10.1083/Jcb.122.3.685  0.481
1993 Wang ZQ, Grigoriadis AE, Wagner EF. Stable murine chondrogenic cell lines derived from c-fos-induced cartilage tumors. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 8: 839-47. PMID 7688930 DOI: 10.1002/Jbmr.5650080710  0.409
1993 Wang ZQ, Ovitt C, Grigoriadis AE, Möhle-Steinlein U, Rüther U, Wagner EF. Bone and haematopoietic defects in mice lacking c-fos. Nature. 360: 741-5. PMID 1465144 DOI: 10.1038/360741A0  0.479
1993 von Ruden T, Stingl L, Ullrich A, Wagner E. Rescue of W-associated mast cell defects in W/Wv bone marrow cells by ectopic expression of normal and mutant epidermal growth factor receptors Blood. 82: 1463-1470. DOI: 10.1182/Blood.V82.5.1463.Bloodjournal8251463  0.397
1993 Hilberg F, Aguzzi A, Howells N, Wagner EF. Erratum: c-Jun is essential for normal mouse development and hepatogenesis Nature. 366: 368-368. DOI: 10.1038/366368A0  0.308
1992 Redemann N, Holzmann B, von Rüden T, Wagner EF, Schlessinger J, Ullrich A. Anti-oncogenic activity of signalling-defective epidermal growth factor receptor mutants. Molecular and Cellular Biology. 12: 491-8. PMID 1346334 DOI: 10.1128/Mcb.12.2.491  0.327
1992 von Ruden T, Kandels S, Radaszkiewicz T, Ullrich A, Wagner E. Development of a lethal mast cell disease in mice reconstituted with bone marrow cells expressing the v-erbB oncogene Blood. 79: 3145-3158. DOI: 10.1182/Blood.V79.12.3145.3145  0.443
1992 Kennedy M, Beug H, Wagner E, Keller G. Factor-dependent erythroid cell lines derived from mice transplanted with hematopoietic cells expressing the v-src oncogene Blood. 79: 180-190. DOI: 10.1182/Blood.V79.1.180.180  0.404
1991 Wagner EF, Alexander WS. Of kit and mouse and man. Current Biology. 1: 356-358. PMID 15336078 DOI: 10.1016/0960-9822(91)90191-X  0.322
1991 Kiefer F, Wagner E, Keller G. Fractionation of mouse bone marrow by adherence separates primitive hematopoietic stem cells from in vitro colony-forming cells and spleen colony-forming cells Blood. 78: 2577-2582. DOI: 10.1182/Blood.V78.10.2577.Bloodjournal78102577  0.378
1991 Wang Z, Grigoriadis A, Möhle-Steinlein U, Wagner E. A novel target cell for c-fos-induced oncogenesis: development of chondrogenic tumours in embryonic stem cell chimeras. The Embo Journal. 10: 2437-2450. DOI: 10.1002/J.1460-2075.1991.Tb07783.X  0.444
1991 Alexander W, Lyman S, Wagner E. Expression of functional c-kit receptors rescues the genetic defect of W mutant mast cells. The Embo Journal. 10: 3683-3691. DOI: 10.1002/J.1460-2075.1991.Tb04936.X  0.445
1990 Montesano R, Pepper MS, Möhle-Steinlein U, Risau W, Wagner EF, Orci L. Increased proteolytic activity is responsible for the aberrant morphogenetic behavior of endothelial cells expressing the middle T oncogene. Cell. 62: 435-445. PMID 2379237 DOI: 10.1016/0092-8674(90)90009-4  0.366
1990 Goralczyk R, Closs EI, Rüther U, Wagner EF, Strauss PG, Erfle V, Schmidt J. Characterization of fos-induced osteogenic tumours and tumour-derived murine cell lines. Differentiation. 44: 122-131. PMID 2178137 DOI: 10.1111/J.1432-0436.1990.Tb00545.X  0.439
1990 Hengerer B, Lindholm D, Heumann R, Rüther U, Wagner EF, Thoenen H. Lesion-induced increase in nerve growth factor mRNA is mediated by c-fos. Proceedings of the National Academy of Sciences of the United States of America. 87: 3899-903. PMID 2111020 DOI: 10.1073/Pnas.87.10.3899  0.354
1990 Wagner EF. EMBO medal review. On transferring genes into stem cells and mice. The Embo Journal. 9: 3024-3032. DOI: 10.1002/J.1460-2075.1990.Tb07498.X  0.353
1989 Williams RL, Risau W, Zerwes HG, Drexler H, Aguzzi A, Wagner EF. Endothelioma cells expressing the polyoma middle T oncogene induce hemangiomas by host cell recruitment. Cell. 57: 1053-63. PMID 2736622 DOI: 10.1016/0092-8674(89)90343-7  0.405
1989 Keller G, Wagner EF. Expression of v-src induces a myeloproliferative disease in bone-marrow-reconstituted mice. Genes & Development. 3: 827-37. PMID 2568314 DOI: 10.1101/Gad.3.6.827  0.399
1989 Rüther U, Wagner EF. The specific consequences of c-fos expression in transgenic mice. Progress in Nucleic Acid Research and Molecular Biology. 36: 235-45. PMID 2499906 DOI: 10.1016/S0079-6603(08)60174-9  0.456
1988 Lindsay Williams R, Courtneidge SA, Wagner EF. Embryonic lethalities and endothelial tumors in chimeric mice expressing polyoma virus middle T oncogene Cell. 52: 121-131. PMID 3345558 DOI: 10.1016/0092-8674(88)90536-3  0.402
1988 Williams RL, Hilton DJ, Pease S, Willson TA, Stewart CL, Gearing DP, Wagner EF, Metcalf D, Nicola NA, Gough NM. Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells. Nature. 336: 684-7. PMID 3143916 DOI: 10.1038/336684A0  0.395
1988 Rüther U, Müller W, Sumida T, Tokuhisa T, Rajewsky K, Wagner EF. c-fos expression interferes with thymus development in transgenic mice. Cell. 53: 847-56. PMID 3133119 DOI: 10.1016/S0092-8674(88)90289-9  0.453
1988 Boulter CA, Wagner EF. Expression of c-src and c-abl in embryonal carcinoma cells and adult mouse tissues. Experimental Cell Research. 179: 214-21. PMID 2458954 DOI: 10.1016/0014-4827(88)90360-6  0.4
1988 Jefferies WA, Rüther U, Wagner EF, Kvist S. Cytolytic T cells recognize a chimeric MHC class I antigen expressed in influenza A infected transgenic mice. The Embo Journal. 7: 3423-3431. DOI: 10.1002/J.1460-2075.1988.Tb03216.X  0.36
1988 Rüden Tv, Wagner EF. Expression of functional human EGF receptor on murine bone marrow cells. The Embo Journal. 7: 2749-2756. DOI: 10.1002/J.1460-2075.1988.Tb03129.X  0.341
1987 Rüther U, Tripodi M, Cortese R, Wagner EF. The human alpha-1-antitrypsin gene is efficiently expressed from two tissue-specific promotors in transgenic mice. Nucleic Acids Research. 15: 7519-29. PMID 3498933 DOI: 10.1093/Nar/15.18.7519  0.328
1987 Keller G, Wagner EF. Efficient expression of foreign genes in mice reconstituted with retrovirus-infected bone marrow cells. Cold Spring Harbor Symposia On Quantitative Biology. 1053-8. PMID 3472752 DOI: 10.1101/Sqb.1986.051.01.122  0.389
1987 Rüther U, Garber C, Komitowski D, Müller R, Wagner EF. Deregulated c-fos expression interferes with normal bone development in transgenic mice. Nature. 325: 412-6. PMID 3027573 DOI: 10.1038/325412A0  0.431
1987 Stewart C, Schuetze S, Vanek M, Wagner E. Expression of retroviral vectors in transgenic mice obtained by embryo infection. The Embo Journal. 6: 383-388. DOI: 10.1002/J.1460-2075.1987.Tb04766.X  0.371
1987 Ciliberto G, Arcone R, Wagner EF, Rüther U. Inducible and tissue-specific expression of human C-reactive protein in transgenic mice. The Embo Journal. 6: 4017-4022. DOI: 10.1002/J.1460-2075.1987.Tb02745.X  0.387
1986 Yu SF, von Rüden T, Kantoff PW, Garber C, Seiberg M, Rüther U, Anderson WF, Wagner EF, Gilboa E. Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 83: 3194-8. PMID 3458176 DOI: 10.1073/Pnas.83.10.3194  0.374
1985 Keller G, Paige C, Gilboa E, Wagner EF. Expression of a foreign gene in myeloid and lymphoid cells derived from multipotent haematopoietic precursors Nature. 318: 149-154. PMID 3903518 DOI: 10.1038/318149A0  0.397
1985 Wagner EF, Keller G, Gilboa E, Rüther U, Stewart C. Gene transfer into murine stem cells and mice using retroviral vectors Cold Spring Harbor Symposia On Quantitative Biology. 50: 691-700. PMID 3868504 DOI: 10.1101/Sqb.1985.050.01.085  0.361
1985 Colberg-Poley AM, Voss SD, Chowdhury K, Stewart CL, Wagner EF, Gruss P. Clustered homeo boxes are differentially expressed during murine development. Cell. 43: 39-45. PMID 2416462 DOI: 10.1016/0092-8674(85)90010-8  0.315
1985 Stewart C, Vanek M, Wagner E. Expression of foreign genes from retroviral vectors in mouse teratocarcinoma chimaeras. The Embo Journal. 4: 3701-3709. DOI: 10.1002/J.1460-2075.1985.Tb04138.X  0.403
1985 Rüther U, Wagner E, Müller R. Analysis of the differentiation-promoting potential of inducible c-fos genes introduced into embryonal carcinoma cells. The Embo Journal. 4: 1775-1781. DOI: 10.1002/J.1460-2075.1985.Tb03850.X  0.431
1985 Wagner E, Vanek M, Vennström B. Transfer of genes into embryonal carcinoma cells by retrovirus infection: efficient expression from an internal promoter. The Embo Journal. 4: 663-666. DOI: 10.1002/J.1460-2075.1985.Tb03680.X  0.379
1984 Müller R, Wagner EF. Differentiation of F9 teratocarcinoma stem cells after transfer of c-fos proto-oncogenes. Nature. 311: 438-42. PMID 6541297 DOI: 10.1038/311438A0  0.399
1984 Wagner EF. Gene transfer into the germ line of mice and into embryonal carcinoma stem cells Philosophical Transactions of the Royal Society B. 307: 313-317. PMID 6151703 DOI: 10.1098/Rstb.1984.0133  0.4
1983 Wagner EF, Covarrubias L, Stewart TA, Mintz B. Prenatal lethalities in mice homozygous for human growth hormone gene sequences integrated in the germ line. Cell. 35: 647-55. PMID 6580963 DOI: 10.1016/0092-8674(83)90097-1  0.541
1982 Steward TA, Wagner EF, Mintz B. Human beta-globin gene sequences injected into mouse eggs, retained in adults, and transmitted to progeny. Science (New York, N.Y.). 217: 1046-8. PMID 6287575 DOI: 10.1126/Science.6287575  0.556
1982 Wagner EF, Mintz B. Transfer of nonselectable genes into mouse teratocarcinoma cells and transcription of the transferred human beta-globin gene. Molecular and Cellular Biology. 2: 190-8. PMID 6287228 DOI: 10.1128/Mcb.2.2.190  0.584
1981 Wagner EF, Stewart TA, Mintz B. The human beta-globin gene and a functional viral thymidine kinase gene in developing mice. Proceedings of the National Academy of Sciences of the United States of America. 78: 5016-20. PMID 6272287 DOI: 10.1073/Pnas.78.8.5016  0.568
1980 Pellicer A, Wagner EF, el-Kareh A, Dewey MJ, Reuser AJ, Silverstein S, Axel R, Mintz B. Introduction of a viral thymidine kinase gene and the human beta-globin gene into developmentally multipotential mouse teratocarcinoma cells. Proceedings of the National Academy of Sciences of the United States of America. 77: 2098-102. PMID 6246522 DOI: 10.1073/Pnas.77.4.2098  0.599
1980 Fabricant JD, Wagner EF, Auer B, Schweiger M. 5-methylcytosine content of DNA during differentiation in mouse teratocarcinoma cells. Experimental Cell Research. 124: 25-9. PMID 499384 DOI: 10.1016/0014-4827(79)90253-2  0.332
1977 Wagner EF, Ponta H, Schweiger M. Development of E.coli virus T1: the pattern of gene expression. Molecular & General Genetics : Mgg. 150: 21-8. PMID 319341 DOI: 10.1007/Bf02425321  0.307
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