| Year |
Citation |
Score |
| 2024 |
Duplaquet L, So K, Ying AW, Li X, Li Y, Qiu X, Li R, Singh S, Wu XS, Liu Q, Qi J, Somerville TDD, Heiling H, Mazzola E, Lee Y, ... ... Kadoch C, et al. Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer. Biorxiv : the Preprint Server For Biology. PMID 38328215 DOI: 10.1101/2024.01.21.576304 |
0.38 |
|
| 2023 |
Valencia AM, Sankar A, van der Sluijs PJ, Satterstrom FK, Fu J, Talkowski ME, Vergano SAS, Santen GWE, Kadoch C. Landscape of mSWI/SNF chromatin remodeling complex perturbations in neurodevelopmental disorders. Nature Genetics. 55: 1400-1412. PMID 37500730 DOI: 10.1038/s41588-023-01451-6 |
0.379 |
|
| 2023 |
Otto JE, Ursu O, Wu AP, Winter EB, Cuoco MS, Ma S, Qian K, Michel BC, Buenrostro JD, Berger B, Regev A, Kadoch C. Structural and functional properties of mSWI/SNF chromatin remodeling complexes revealed through single-cell perturbation screens. Molecular Cell. PMID 37028419 DOI: 10.1016/j.molcel.2023.03.013 |
0.442 |
|
| 2023 |
Battistello E, Hixon KA, Comstock DE, Collings CK, Chen X, Rodriguez Hernaez J, Lee S, Cervantes KS, Hinkley MM, Ntatsoulis K, Cesarano A, Hockemeyer K, Haining WN, Witkowski MT, Qi J, ... ... Kadoch C, et al. Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion. Molecular Cell. PMID 36944333 DOI: 10.1016/j.molcel.2023.02.026 |
0.318 |
|
| 2023 |
Wei J, Patil A, Collings CK, Alfajaro MM, Liang Y, Cai WL, Strine MS, Filler RB, DeWeirdt PC, Hanna RE, Menasche BL, Ökten A, Peña-Hernández MA, Klein J, McNamara A, ... ... Kadoch C, et al. Pharmacological disruption of mSWI/SNF complex activity restricts SARS-CoV-2 infection. Nature Genetics. PMID 36894709 DOI: 10.1038/s41588-023-01307-z |
0.316 |
|
| 2022 |
St Pierre R, Collings CK, Samé Guerra DD, Widmer CJ, Bolonduro O, Mashtalir N, Sankar A, Liang Y, Bi WL, Gerkes EH, Ramesh V, Qi J, Smith MJ, Meredith DM, Kadoch C. SMARCE1 deficiency generates a targetable mSWI/SNF dependency in clear cell meningioma. Nature Genetics. PMID 35681054 DOI: 10.1038/s41588-022-01077-0 |
0.487 |
|
| 2022 |
Zullow HJ, Sankar A, Ingram DR, Samé Guerra DD, D'Avino AR, Collings CK, Lazcano R, Wang WL, Liang Y, Qi J, Lazar AJ, Kadoch C. The FUS::DDIT3 fusion oncoprotein inhibits BAF complex targeting and activity in myxoid liposarcoma. Molecular Cell. PMID 35390276 DOI: 10.1016/j.molcel.2022.03.019 |
0.468 |
|
| 2021 |
Huang X, Park KM, Gontarz P, Zhang B, Pan J, McKenzie Z, Fischer LA, Dong C, Dietmann S, Xing X, Shliaha PV, Yang J, Li D, Ding J, Lungjangwa T, ... ... Kadoch C, et al. OCT4 cooperates with distinct ATP-dependent chromatin remodelers in naïve and primed pluripotent states in human. Nature Communications. 12: 5123. PMID 34446700 DOI: 10.1038/s41467-021-25107-3 |
0.368 |
|
| 2021 |
Mashtalir N, Dao HT, Sankar A, Liu H, Corin AJ, Bagert JD, Ge EJ, D'Avino AR, Filipovski M, Michel BC, Dann GP, Muir TW, Kadoch C. Chromatin landscape signals differentially dictate the activities of mSWI/SNF family complexes. Science (New York, N.Y.). 373: 306-315. PMID 34437148 DOI: 10.1126/science.abf8705 |
0.404 |
|
| 2020 |
Barish S, Barakat TS, Michel BC, Mashtalir N, Phillips JB, Valencia AM, Ugur B, Wegner J, Scott TM, Bostwick B, Murdock DR, Dai H, Perenthaler E, Nikoncuk A, ... ... Kadoch C, et al. BICRA, a SWI/SNF Complex Member, Is Associated with BAF-Disorder Related Phenotypes in Humans and Model Organisms. American Journal of Human Genetics. PMID 33232675 DOI: 10.1016/j.ajhg.2020.11.003 |
0.353 |
|
| 2020 |
Mashtalir N, Suzuki H, Farrell DP, Sankar A, Luo J, Filipovski M, D'Avino AR, St Pierre R, Valencia AM, Onikubo T, Roeder RG, Han Y, He Y, Ranish JA, DiMaio F, ... ... Kadoch C, et al. A Structural Model of the Endogenous Human BAF Complex Informs Disease Mechanisms. Cell. PMID 33053319 DOI: 10.1016/j.cell.2020.09.051 |
0.449 |
|
| 2020 |
Centore RC, Sandoval GJ, Soares LMM, Kadoch C, Chan HM. Mammalian SWI/SNF Chromatin Remodeling Complexes: Emerging Mechanisms and Therapeutic Strategies. Trends in Genetics : Tig. PMID 32873422 DOI: 10.1016/J.Tig.2020.07.011 |
0.49 |
|
| 2020 |
Shi H, Tao T, Abraham BJ, Durbin AD, Zimmerman MW, Kadoch C, Look AT. ARID1A loss in neuroblastoma promotes the adrenergic-to-mesenchymal transition by regulating enhancer-mediated gene expression. Science Advances. 6: eaaz3440. PMID 32832616 DOI: 10.1126/Sciadv.Aaz3440 |
0.501 |
|
| 2020 |
McBride MJ, Mashtalir N, Winter EB, Dao HT, Filipovski M, D'Avino AR, Seo HS, Umbreit NT, St Pierre R, Valencia AM, Qian K, Zullow HJ, Jaffe JD, Dhe-Paganon S, Muir TW, ... Kadoch C, et al. The nucleosome acidic patch and H2A ubiquitination underlie mSWI/SNF recruitment in synovial sarcoma. Nature Structural & Molecular Biology. PMID 32747783 DOI: 10.1038/S41594-020-0466-9 |
0.481 |
|
| 2020 |
Shu S, Wu HJ, Ge JY, Zeid R, Harris IS, Jovanović B, Murphy K, Wang B, Qiu X, Endress JE, Reyes J, Lim K, Font-Tello A, Syamala S, Xiao T, ... ... Kadoch C, et al. Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer. Molecular Cell. PMID 32416067 DOI: 10.1016/J.Molcel.2020.04.027 |
0.33 |
|
| 2020 |
Abou Alaiwi S, Nassar AH, Xie W, Bakouny Z, Berchuck JE, Braun DA, Baca SC, Nuzzo PV, Flippot R, Mouhieddine TH, Spurr LF, Li YY, Li T, Flaifel A, Steinharter JA, ... ... Kadoch C, et al. Mammalian SWI/SNF complex genomic alterations and immune checkpoint blockade in solid tumors. Cancer Immunology Research. PMID 32321774 DOI: 10.1158/2326-6066.Cir-19-0866 |
0.427 |
|
| 2020 |
Baranov E, McBride MJ, Bellizzi AM, Ligon AH, Fletcher CDM, Kadoch C, Hornick JL. A Novel SS18-SSX Fusion-specific Antibody for the Diagnosis of Synovial Sarcoma. The American Journal of Surgical Pathology. PMID 32141887 DOI: 10.1097/Pas.0000000000001447 |
0.313 |
|
| 2020 |
Forrest SJ, Al-Ibraheemi A, Doan D, Ward A, Clinton CM, Putra J, Pinches RS, Kadoch C, Chi S, Dubois SG, Leavey P, LeBoeuf NR, Mullen E, Collins N, Church AJ, et al. Genomic and immunologic characterization of INI1-deficient pediatric cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32122923 DOI: 10.1158/1078-0432.Ccr-19-3089 |
0.394 |
|
| 2020 |
Xu G, Chhangawala S, Cocco E, Razavi P, Cai Y, Otto JE, Ferrando L, Selenica P, Ladewig E, Chan C, Da Cruz Paula A, Witkin M, Cheng Y, Park J, Serna-Tamayo C, ... ... Kadoch C, et al. ARID1A determines luminal identity and therapeutic response in estrogen-receptor-positive breast cancer. Nature Genetics. PMID 31932695 DOI: 10.1038/S41588-019-0554-0 |
0.411 |
|
| 2020 |
Forrest SJ, Al-Ibraheemi A, Ward A, Doan D, Clinton C, Putra J, Pinches RS, Kadoch C, Chi S, Dubois SG, Leavy P, Collins N, Church A, Janeway KA. Abstract A16: Genomic and immunologic characterization of a cohort of INI1-deficient pediatric cancers Cancer Research. 80. DOI: 10.1158/1538-7445.Pedca19-A16 |
0.416 |
|
| 2020 |
Shi H, Tao T, Abraham BJ, Durbin AD, Zimmerman MW, Kadoch C, Look AT. ARID1A loss in neuroblastoma promotes the adrenergic-to-mesenchymal transition by regulating enhancer-mediated gene expression Science Advances. 6: eaaz3440. DOI: 10.1126/sciadv.aaz3440 |
0.41 |
|
| 2019 |
Valencia AM, Collings CK, Dao HT, St Pierre R, Cheng YC, Huang J, Sun ZY, Seo HS, Mashtalir N, Comstock DE, Bolonduro O, Vangos NE, Yeoh ZC, Dornon MK, Hermawan C, ... ... Kadoch C, et al. Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling. Cell. PMID 31759698 DOI: 10.1016/J.Cell.2019.10.044 |
0.515 |
|
| 2019 |
Inoue D, Chew GL, Liu B, Michel BC, Pangallo J, D'Avino AR, Hitchman T, North K, Lee SC, Bitner L, Block A, Moore AR, Yoshimi A, Escobar-Hoyos L, Cho H, ... ... Kadoch C, et al. Spliceosomal disruption of the non-canonical BAF complex in cancer. Nature. PMID 31597964 DOI: 10.1038/S41586-019-1646-9 |
0.496 |
|
| 2019 |
Kadoch C. Diverse compositions and functions of chromatin remodeling machines in cancer. Science Translational Medicine. 11. PMID 31316005 DOI: 10.1126/Scitranslmed.Aay1018 |
0.414 |
|
| 2019 |
Hong AL, Tseng YY, Wala JA, Kim WJ, Kynnap BD, Doshi MB, Kugener G, Sandoval GJ, Howard TP, Li J, Yang X, Tillgren M, Ghandi M, Sayeed A, Deasy R, ... ... Kadoch C, et al. Renal medullary carcinomas depend upon loss and are sensitive to proteasome inhibition. Elife. 8. PMID 30860482 DOI: 10.7554/Elife.44161 |
0.354 |
|
| 2019 |
Pan J, McKenzie ZM, D'Avino AR, Mashtalir N, Lareau CA, St Pierre R, Wang L, Shilatifard A, Kadoch C. The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity-independent genomic targeting. Nature Genetics. PMID 30858614 DOI: 10.1038/S41588-019-0363-5 |
0.518 |
|
| 2019 |
Valencia AM, Kadoch C. Chromatin regulatory mechanisms and therapeutic opportunities in cancer. Nature Cell Biology. 21: 152-161. PMID 30602726 DOI: 10.1038/S41556-018-0258-1 |
0.468 |
|
| 2019 |
Inoue D, Guo-Liang C, Liu B, Lee SC, Michel BC, Pangallo J, D'Avino AR, North K, Bitner LE, Xiao M, Kobayashi S, Yoshimi A, Cho H, Lu SX, Taylor J, ... Kadoch C, et al. Spliceosomal Disruption of the Non-Canonical SWI/SNF Chromatin Remodeling Complex in SF3B1 Mutant Leukemias Blood. 134: 637-637. DOI: 10.1182/Blood-2019-124616 |
0.474 |
|
| 2019 |
Kadoch C. Structure and Function of ATP-Dependent Chromatin Remodeling Complexes in Human Cancer Blood. 134: SCI-48-SCI-48. DOI: 10.1182/Blood-2019-121033 |
0.561 |
|
| 2019 |
Sabedot TS, Cassel SH, Gao GF, Lareau CA, Cherniack A, Lazar A, Kadoch C, Noushmehr H. Abstract 907: Bioinformatic method to define epigenetically regulated enhancer elements associated with cancer Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-907 |
0.345 |
|
| 2019 |
Soares L, Bocker M, Zhou Q, Kadoch C, Chan HM. Abstract 1653: Application of high-density tiling CRISPR screen technology to identify chromatin remodeler complex targets for drug discovery Cancer Research. 79: 1653-1653. DOI: 10.1158/1538-7445.Am2019-1653 |
0.481 |
|
| 2018 |
Menotti M, Ambrogio C, Cheong TC, Pighi C, Mota I, Cassel SH, Compagno M, Wang Q, Dall'Olio R, Minero VG, Poggio T, Sharma GG, Patrucco E, Mastini C, Choudhari R, ... ... Kadoch C, et al. Wiskott-Aldrich syndrome protein (WASP) is a tumor suppressor in T cell lymphoma. Nature Medicine. PMID 30510251 DOI: 10.1038/S41591-018-0262-9 |
0.31 |
|
| 2018 |
Zhang H, Pandey S, Travers M, Sun H, Morton G, Madzo J, Chung W, Khowsathit J, Perez-Leal O, Barrero CA, Merali C, Okamoto Y, Sato T, Pan J, Garriga J, ... ... Kadoch C, et al. Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer. Cell. 175: 1244-1258.e26. PMID 30454645 DOI: 10.1016/J.Cell.2018.09.051 |
0.394 |
|
| 2018 |
Michel BC, D'Avino AR, Cassel SH, Mashtalir N, McKenzie ZM, McBride MJ, Valencia AM, Zhou Q, Bocker M, Soares LMM, Pan J, Remillard DI, Lareau CA, Zullow HJ, Fortoul N, ... ... Kadoch C, et al. A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation. Nature Cell Biology. PMID 30397315 DOI: 10.1038/S41556-018-0221-1 |
0.526 |
|
| 2018 |
Mashtalir N, D'Avino AR, Michel BC, Luo J, Pan J, Otto JE, Zullow HJ, McKenzie ZM, Kubiak RL, St Pierre R, Valencia AM, Poynter SJ, Cassel SH, Ranish JA, Kadoch C. Modular Organization and Assembly of SWI/SNF Family Chromatin Remodeling Complexes. Cell. PMID 30343899 DOI: 10.1016/J.Cell.2018.09.032 |
0.531 |
|
| 2018 |
Sandoval GJ, Pulice JL, Pakula H, Schenone M, Takeda DY, Pop M, Boulay G, Williamson KE, McBride MJ, Pan J, St Pierre R, Hartman E, Garraway LA, Carr SA, Rivera MN, ... ... Kadoch C, et al. Binding of TMPRSS2-ERG to BAF Chromatin Remodeling Complexes Mediates Prostate Oncogenesis. Molecular Cell. PMID 30078722 DOI: 10.1016/J.Molcel.2018.06.040 |
0.465 |
|
| 2018 |
McBride MJ, Pulice JL, Beird HC, Ingram DR, D'Avino AR, Shern JF, Charville GW, Hornick JL, Nakayama RT, Garcia-Rivera EM, Araujo DM, Wang WL, Tsai JW, Yeagley M, Wagner AJ, ... ... Kadoch C, et al. The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma. Cancer Cell. PMID 29861296 DOI: 10.1016/J.Ccell.2018.05.002 |
0.524 |
|
| 2018 |
Pan J, Meyers RM, Michel BC, Mashtalir N, Sizemore AE, Wells JN, Cassel SH, Vazquez F, Weir BA, Hahn WC, Marsh JA, Tsherniak A, Kadoch C. Interrogation of Mammalian Protein Complex Structure, Function, and Membership Using Genome-Scale Fitness Screens. Cell Systems. PMID 29778836 DOI: 10.1016/J.Cels.2018.04.011 |
0.435 |
|
| 2018 |
McBride MJ, Kadoch C. Disruption of mammalian SWI/SNF and Polycomb complexes in human sarcomas: mechanisms and therapeutic opportunities. The Journal of Pathology. PMID 29359803 DOI: 10.1002/Path.5042 |
0.56 |
|
| 2018 |
Geng H, Tiret B, Gao H, Kadoch C, Lu M, Chen L, Park I, Melkus G, Elkhaled A, Kurhanewicz J, Drew L, Degorce S, Mayo M, Dillman K, Anjum R, et al. Application of Hyperpolarized 13C Magnetic Resonance Imaging to Detect Target Inhibition of NFkB Activation in Preclinical Patient-Derived Models of CNS Lymphoma Blood. 132: 2840-2840. DOI: 10.1182/Blood-2018-99-117625 |
0.365 |
|
| 2018 |
McBride MJ, Pulice JL, Nakayama RT, Mashtalir N, Ingram DR, Jaffe JD, Shern JF, Khan J, Hornick JL, Lazar AJ, Kadoch C. Abstract PR11: SSX-mediated chromatin engagement and targeting of BAF complexes activates oncogenic transcription in synovial sarcoma Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Sarcomas17-Pr11 |
0.562 |
|
| 2018 |
Boulay G, Sandoval GJ, Riggi N, Iyer S, Buisson R, Naigles B, Awad ME, Rengarajan S, Volorio A, McBride MJ, Broye LC, Zou L, Stamenkovic I, Kadoch C, Rivera MN. Abstract PR09: Cancer-specific retargeting of BAF complexes by a prion-like domain Cancer Research. 78. DOI: 10.1158/1538-7445.Pedca17-Pr09 |
0.518 |
|
| 2018 |
Hong AL, Tseng Y, Kynnap BD, Doshi MB, Wala J, Sandoval G, Church AJ, Mullen E, Kadoch C, Roberts CWM, Beroukhim R, Boehm JS, Hahn WC. Abstract B18: Modeling renal medullary carcinomas identifies druggable vulnerabilities in SMARCB1-deficient cancers Cancer Research. 78. DOI: 10.1158/1538-7445.Pedca17-B18 |
0.389 |
|
| 2017 |
Otto JE, Kadoch C. A Two-Faced mSWI/SNF Subunit: Dual Roles for ARID1A in Tumor Suppression and Oncogenicity in the Liver. Cancer Cell. 32: 542-543. PMID 29136498 DOI: 10.1016/J.Ccell.2017.10.014 |
0.399 |
|
| 2017 |
Nakayama RT, Pulice JL, Valencia AM, McBride MJ, McKenzie ZM, Gillespie MA, Ku WL, Teng M, Cui K, Williams RT, Cassel SH, Qing H, Widmer CJ, Demetri GD, Irizarry RA, ... ... Kadoch C, et al. SMARCB1 is required for widespread BAF complex-mediated activation of enhancers and bivalent promoters. Nature Genetics. PMID 28945250 DOI: 10.1038/Ng.3958 |
0.701 |
|
| 2017 |
Boulay G, Sandoval GJ, Riggi N, Iyer S, Buisson R, Naigles B, Awad ME, Rengarajan S, Volorio A, McBride MJ, Broye LC, Zou L, Stamenkovic I, Kadoch C, Rivera MN. Cancer-Specific Retargeting of BAF Complexes by a Prion-like Domain. Cell. PMID 28844694 DOI: 10.1016/J.Cell.2017.07.036 |
0.522 |
|
| 2017 |
Michel BC, Kadoch C. A SMARCD2-containing mSWI/SNF complex is required for granulopoiesis. Nature Genetics. 49: 655-657. PMID 28442792 DOI: 10.1038/Ng.3853 |
0.501 |
|
| 2017 |
Pulice JL, Kadoch C. Composition and Function of Mammalian SWI/SNF Chromatin Remodeling Complexes in Human Disease. Cold Spring Harbor Symposia On Quantitative Biology. PMID 28408647 DOI: 10.1101/Sqb.2016.81.031021 |
0.521 |
|
| 2017 |
Pierre RS, Kadoch C. Mammalian SWI/SNF complexes in cancer: emerging therapeutic opportunities. Current Opinion in Genetics & Development. 42: 56-67. PMID 28391084 DOI: 10.1016/J.Gde.2017.02.004 |
0.591 |
|
| 2017 |
Miller EL, Hargreaves DC, Kadoch C, Chang CY, Calarco JP, Hodges C, Buenrostro JD, Cui K, Greenleaf WJ, Zhao K, Crabtree GR. TOP2 synergizes with BAF chromatin remodeling for both resolution and formation of facultative heterochromatin. Nature Structural & Molecular Biology. PMID 28250416 DOI: 10.1038/Nsmb.3384 |
0.744 |
|
| 2017 |
Michel BC, D'Avino AR, Pan J, Meyers RM, Tsherniak A, Grandi P, Humphreys P, Garton N, Prinja RK, Kadoch C. Abstract PR15: BRD9 defines a novel mammalian SWI/SNF (BAF) complex configuration which supports proliferation in AML Clinical Cancer Research. 23. DOI: 10.1158/1557-3265.Hemmal17-Pr15 |
0.564 |
|
| 2017 |
Hong AL, Tseng Y, Kynnap BD, Doshi MB, Sandoval G, Oh C, Sayeed A, Shubhroz G, Church AJ, Keskula P, Peng A, Clemons PA, Tsherniak A, Vazquez F, Rodriguez-Galindo C, ... ... Kadoch C, et al. Abstract B17: Identification of Druggable Targets through Functional Multi-Omics in Renal Medullary Carcinoma Molecular Cancer Therapeutics. 16. DOI: 10.1158/1538-8514.Synthleth-B17 |
0.35 |
|
| 2017 |
Shi H, Tao T, Kadoch C, Look T. Abstract 802: Loss of function of Arid1a synergizes with MYCN in neuroblastoma pathogenesis Cancer Research. 77: 802-802. DOI: 10.1158/1538-7445.Am2017-802 |
0.516 |
|
| 2017 |
Pan J, Meyers RM, Michel BC, Sizemore AE, Vazquez F, Weir BA, Hahn WC, Tsherniak A, Kadoch C. Abstract 5559: Using cancer dependency data to discover tumor suppressive and oncogenic functional modules Cancer Research. 77: 5559-5559. DOI: 10.1158/1538-7445.Am2017-5559 |
0.383 |
|
| 2017 |
McBride MJ, Pulice JL, Nakayama RT, Mashtalir N, Ingram DR, Shern JF, Khan J, Hornick JL, Lazar AJ, Kadoch C. Abstract 3875: SSX drives gain-of-function BAF complex chromatin affinity and genomic targeting in synovial sarcoma Cancer Research. 77: 3875-3875. DOI: 10.1158/1538-7445.Am2017-3875 |
0.562 |
|
| 2017 |
Michel BC, Pan J, Meyers RM, Grandi P, Humphreys PG, Garton NG, Prinja RK, Kadoch C. Abstract 1020: BRD9 defines a novel mammalian SWI/SNF (BAF) complex configuration which supports proliferation in AML Cancer Research. 77: 1020-1020. DOI: 10.1158/1538-7445.Am2017-1020 |
0.557 |
|
| 2016 |
Kadoch C, Williams RT, Calarco JP, Miller EL, Weber CM, Braun SM, Pulice JL, Chory EJ, Crabtree GR. Dynamics of BAF-Polycomb complex opposition on heterochromatin in normal and oncogenic states. Nature Genetics. PMID 27941796 DOI: 10.1038/Ng.3734 |
0.778 |
|
| 2016 |
Stanton BZ, Hodges C, Calarco JP, Braun SM, Ku WL, Kadoch C, Zhao K, Crabtree GR. Smarca4 ATPase mutations disrupt direct eviction of PRC1 from chromatin. Nature Genetics. PMID 27941795 DOI: 10.1038/Ng.3735 |
0.712 |
|
| 2016 |
Poynter ST, Kadoch C. Polycomb and trithorax opposition in development and disease. Wiley Interdisciplinary Reviews. Developmental Biology. PMID 27581385 DOI: 10.1002/Wdev.244 |
0.38 |
|
| 2016 |
Hingorani P, Janeway K, Crompton BD, Kadoch C, Mackall CL, Khan J, Shern JF, Schiffman J, Mirabello L, Savage SA, Ladanyi M, Meltzer P, Bult CJ, Adamson PC, Lupo PJ, et al. Current state of pediatric sarcoma biology and opportunities for future discovery: A report from the sarcoma translational research workshop. Cancer Genetics. PMID 27132463 DOI: 10.1016/J.Cancergen.2016.03.004 |
0.349 |
|
| 2016 |
Kadoch C. Lifting Up the HAT: Synthetic Lethal Screening Reveals a Novel Vulnerability at the CBP-p300 Axis. Cancer Discovery. 6: 350-2. PMID 27045018 DOI: 10.1158/2159-8290.Cd-16-0163 |
0.333 |
|
| 2016 |
Kadoch C, Copeland RA, Keilhack H. PRC2 and SWI/SNF Chromatin Remodeling Complexes in Health and Disease. Biochemistry. PMID 26836503 DOI: 10.1021/Acs.Biochem.5B01191 |
0.469 |
|
| 2016 |
Geng H, Gao H, Kadoch C, Lu M, Chen L, Anjum R, Drew L, Degorce S, Dillman K, Mayo M, Anderson S, Collins C, Lowell CA, Rubenstein JL. Targeting NF-KB Activation in Novel Intracranial Models of CNS Lymphoma Blood. 128: 777-777. DOI: 10.1182/Blood.V128.22.777.777 |
0.376 |
|
| 2016 |
Kadoch C. Abstract IA30: BAF complex structure and function in development and disease Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Devbiolca15-Ia30 |
0.598 |
|
| 2016 |
Sandoval GJ, Pulice JL, Takeda DY, Schenone MA, Pop M, Boulay G, Rivera MN, Ronco L, Hahn WC, Kadoch C. Abstract 882: TMPRSS2-ERG drives global mistargeting of mammalian SWI/SNF (BAF) complexes in prostate cancer Cancer Research. 76: 882-882. DOI: 10.1158/1538-7445.Am2016-882 |
0.464 |
|
| 2016 |
Nakayama R, Williams RT, Cassel SH, Teng M, Irizarry RA, Demetri GD, Kadoch C. Abstract 2658: Genome-wide mistargeting of oncogenic SWI/SNF(BAF) complexes in SMARCB1(BAF47)-deficient sarcomas Cancer Research. 76: 2658-2658. DOI: 10.1158/1538-7445.Am2016-2658 |
0.589 |
|
| 2015 |
Kadoch C, Crabtree GR. Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics. Science Advances. 1: e1500447. PMID 26601204 DOI: 10.1126/Sciadv.1500447 |
0.686 |
|
| 2013 |
Kadoch C, Hargreaves DC, Hodges C, Elias L, Ho L, Ranish J, Crabtree GR. Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy. Nature Genetics. 45: 592-601. PMID 23644491 DOI: 10.1038/Ng.2628 |
0.737 |
|
| 2013 |
Kadoch C, Crabtree GR. Reversible disruption of mSWI/SNF (BAF) complexes by the SS18-SSX oncogenic fusion in synovial sarcoma. Cell. 153: 71-85. PMID 23540691 DOI: 10.1016/J.Cell.2013.02.036 |
0.643 |
|
| 2013 |
Kadoch C, Crabtree GR. Reversing the oncogenic roles of misdirected chromatin remodeling: Mechanistic insights into the SS18-SSX fusion protein in synovial sarcoma. Journal of Clinical Oncology. 31: 10515-10515. DOI: 10.1200/Jco.2013.31.15_Suppl.10515 |
0.65 |
|
| 2013 |
Gao H, Anderson S, Kadoch C, Maiti M, Chen L, Yao D, Melkus G, Wang M, Ren Y, Breider M, Heise C, Lowell CA, Collins C, Rubenstein JL. Novel Intracranial Xenografts Of CNS Lymphoma Implicate a Role For Cereblon As a Mediator Of Lenalidomide Efficacy Blood. 122: 374-374. DOI: 10.1182/Blood.V122.21.374.374 |
0.326 |
|
| 2013 |
Kadoch C, Crabtree GR. Abstract PR05: Reversing the oncogenic roles of misdirected chromatin remodeling: Disruption of mSWI/SNF (BAF) complexes by the SS18-SSX fusion in human synovial sarcoma Cancer Research. 73. DOI: 10.1158/1538-7445.Cec13-Pr05 |
0.608 |
|
| 2013 |
Kadoch C, Crabtree GR. Abstract 2315: Reversible disruption of mSWI/SNF-like BAF complexes by the SS18-SSX oncogenic fusion in synovial sarcoma. Cancer Research. 73: 2315-2315. DOI: 10.1158/1538-7445.Am2013-2315 |
0.581 |
|
| 2011 |
Gao H, Anderson S, Chen L, Kadoch C, Hann BC, Lowell C, Collins C, Rubenstein JL. Genomic and Molecular Properties of Relapsed CNS Lymphoma Using Novel Primary Meningeal Lymphoma Cell Lines and Intracranial Xenografts, Blood. 118: 3477-3477. DOI: 10.1182/Blood.V118.21.3477.3477 |
0.364 |
|
| 2011 |
Kadoch C, Wong V, Chen L, Bet-Lachin A, Roy R, Hyun W, Behler C, Lowell C, Rubenstein JL. Dynamic Changes in Macrophage Polarization Correlate with Progression and Response in CNS Lymphoma: Insights Into the Transcriptome of Lymphoma-Associated M2 Macrophages, Blood. 118: 3219-3219. DOI: 10.1182/Blood.V118.21.3219.3219 |
0.326 |
|
| 2010 |
Kadoch C, Wong VS, Rambaldo TC, Hyun WC, Gao HX, Lowell CA, Rubenstein JL. Abstract 5580: Macrophage polarization and acquired resistance to rituximab in CNS lymphoma Cancer Research. 70: 5580-5580. DOI: 10.1158/1538-7445.Am10-5580 |
0.329 |
|
| 2010 |
Wong VS, Chen L, Kadoch C, Tsang A, Siu L, Lowell C, Rubenstein JL. Abstract 2728: Multivariate analysis of cerebrospinal fluid protein biomarkers in central nervous system lymphoma patients and controls Cancer Research. 70: 2728-2728. DOI: 10.1158/1538-7445.Am10-2728 |
0.317 |
|
| 2009 |
Kadoch C, Dinca EB, Voicu R, Chen L, Nguyen D, Parikh S, Karrim J, Shuman MA, Lowell CA, Treseler PA, James CD, Rubenstein JL. Pathologic correlates of primary central nervous system lymphoma defined in an orthotopic xenograft model. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 1989-97. PMID 19276270 DOI: 10.1158/1078-0432.Ccr-08-2054 |
0.37 |
|
| 2008 |
Roy S, Josephson SA, Fridlyand J, Karch J, Kadoch C, Karrim J, Damon L, Treseler P, Kunwar S, Shuman MA, Jones T, Becker CH, Schulman H, Rubenstein JL. Protein biomarker identification in the CSF of patients with CNS lymphoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 96-105. PMID 18056677 DOI: 10.1200/Jco.2007.12.1053 |
0.312 |
|
| 2006 |
Kadoch C, Treseler P, Rubenstein JL. Molecular pathogenesis of primary central nervous system lymphoma. Neurosurgical Focus. 21: E1. PMID 17134111 DOI: 10.3171/Foc.2006.21.5.2 |
0.31 |
|
| Show low-probability matches. |