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Abraham Kovoor, Ph.D. - Publications

Affiliations: 
Neuropharmacology University of Washington, Seattle, Seattle, WA 
Area:
Opiods
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22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Schrader JM, Irving CM, Octeau JC, Christian JA, Aballo TJ, Kareemo DJ, Conti J, Camberg JL, Lane JR, Javitch JA, Kovoor A. The differential actions of clozapine and other antipsychotic drugs on the translocation of dopamine D2 receptors to the cell-surface. The Journal of Biological Chemistry. PMID 30670597 DOI: 10.1074/Jbc.Ra118.004682  0.4
2014 Octeau JC, Schrader JM, Masuho I, Sharma M, Aiudi C, Chen CK, Kovoor A, Celver J. G protein beta 5 is targeted to D2-dopamine receptor-containing biochemical compartments and blocks dopamine-dependent receptor internalization. Plos One. 9: e105791. PMID 25162404 DOI: 10.1371/Journal.Pone.0105791  0.488
2013 Cox CJ, Sharma M, Leckman JF, Zuccolo J, Zuccolo A, Kovoor A, Swedo SE, Cunningham MW. Brain human monoclonal autoantibody from sydenham chorea targets dopaminergic neurons in transgenic mice and signals dopamine D2 receptor: implications in human disease. Journal of Immunology (Baltimore, Md. : 1950). 191: 5524-41. PMID 24184556 DOI: 10.4049/Jimmunol.1102592  0.33
2013 Celver J, Sharma M, Thanawala V, Christopher Octeau J, Kovoor A. Arrestin-dependent but G-protein coupled receptor kinase-independent uncoupling of D2-dopamine receptors. Journal of Neurochemistry. 127: 57-65. PMID 23815307 DOI: 10.1111/Jnc.12359  0.485
2013 Sharma M, Celver J, Octeau JC, Kovoor A. Plasma membrane compartmentalization of D2 dopamine receptors. The Journal of Biological Chemistry. 288: 12554-68. PMID 23493394 DOI: 10.1074/Jbc.M112.443945  0.347
2012 Celver J, Sharma M, Kovoor A. D(2)-Dopamine receptors target regulator of G protein signaling 9-2 to detergent-resistant membrane fractions. Journal of Neurochemistry. 120: 56-69. PMID 22035199 DOI: 10.1111/J.1471-4159.2011.07559.X  0.433
2011 Waugh JL, Celver J, Sharma M, Dufresne RL, Terzi D, Risch SC, Fairbrother WG, Neve RL, Kane JP, Malloy MJ, Pullinger CR, Gu HF, Tsatsanis C, Hamilton SP, Gold SJ, ... ... Kovoor A, et al. Association between regulator of G protein signaling 9-2 and body weight. Plos One. 6: e27984. PMID 22132185 DOI: 10.1371/Journal.Pone.0027984  0.312
2011 Sharma M, Celver J, Kovoor A. Regulator of G protein signaling 9-2 (RGS9-2) mRNA is up regulated during neuronal differentiation of mouse embryonic stem cells. Neuroscience Letters. 502: 123-8. PMID 21616123 DOI: 10.1016/J.Neulet.2011.05.021  0.305
2010 Celver J, Sharma M, Kovoor A. RGS9-2 mediates specific inhibition of agonist-induced internalization of D2-dopamine receptors. Journal of Neurochemistry. 114: 739-49. PMID 20477943 DOI: 10.1111/J.1471-4159.2010.06805.X  0.474
2010 Rochdi MD, Vargas GA, Carpentier E, Oligny-Longpré G, Chen S, Kovoor A, Gitelman SE, Rosenthal SM, von Zastrow M, Bouvier M. Functional characterization of vasopressin type 2 receptor substitutions (R137H/C/L) leading to nephrogenic diabetes insipidus and nephrogenic syndrome of inappropriate antidiuresis: implications for treatments. Molecular Pharmacology. 77: 836-45. PMID 20159941 DOI: 10.1124/Mol.109.061804  0.347
2010 Masuho I, Celver J, Kovoor A, Martemyanov KA. Membrane anchor R9AP potentiates GTPase-accelerating protein activity of RGS11 x Gbeta5 complex and accelerates inactivation of the mGluR6-G(o) signaling. The Journal of Biological Chemistry. 285: 4781-7. PMID 20007977 DOI: 10.1074/Jbc.M109.058511  0.33
2005 Kovoor A, Seyffarth P, Ebert J, Barghshoon S, Chen CK, Schwarz S, Axelrod JD, Cheyette BN, Simon MI, Lester HA, Schwarz J. D2 dopamine receptors colocalize regulator of G-protein signaling 9-2 (RGS9-2) via the RGS9 DEP domain, and RGS9 knock-out mice develop dyskinesias associated with dopamine pathways. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2157-65. PMID 15728856 DOI: 10.1523/Jneurosci.2840-04.2005  0.379
2003 Rahman Z, Schwarz J, Gold SJ, Zachariou V, Wein MN, Choi KH, Kovoor A, Chen CK, DiLeone RJ, Schwarz SC, Selley DE, Sim-Selley LJ, Barrot M, Luedtke RR, Self D, et al. RGS9 modulates dopamine signaling in the basal ganglia. Neuron. 38: 941-52. PMID 12818179 DOI: 10.1016/S0896-6273(03)00321-0  0.353
2001 Celver JP, Lowe J, Kovoor A, Gurevich VV, Chavkin C. Threonine 180 is required for G-protein-coupled receptor kinase 3- and beta-arrestin 2-mediated desensitization of the mu-opioid receptor in Xenopus oocytes. The Journal of Biological Chemistry. 276: 4894-900. PMID 11060299 DOI: 10.1074/Jbc.M007437200  0.48
2000 Kovoor A, Chen CK, He W, Wensel TG, Simon MI, Lester HA. Co-expression of Gbeta5 enhances the function of two Ggamma subunit-like domain-containing regulators of G protein signaling proteins. The Journal of Biological Chemistry. 275: 3397-402. PMID 10652332 DOI: 10.1074/Jbc.275.5.3397  0.303
1999 Appleyard SM, Celver J, Pineda V, Kovoor A, Wayman GA, Chavkin C. Agonist-dependent desensitization of the kappa opioid receptor by G protein receptor kinase and beta-arrestin. The Journal of Biological Chemistry. 274: 23802-7. PMID 10446141 DOI: 10.1074/Jbc.274.34.23802  0.399
1999 Jin W, Brown S, Roche JP, Hsieh C, Celver JP, Kovoor A, Chavkin C, Mackie K. Distinct domains of the CB1 cannabinoid receptor mediate desensitization and internalization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 3773-80. PMID 10234009 DOI: 10.1523/Jneurosci.19-10-03773.1999  0.458
1999 Kovoor A, Celver J, Abdryashitov RI, Chavkin C, Gurevich VV. Targeted construction of phosphorylation-independent beta-arrestin mutants with constitutive activity in cells. The Journal of Biological Chemistry. 274: 6831-4. PMID 10066734 DOI: 10.1074/Jbc.274.11.6831  0.432
1998 Kovoor A, Celver JP, Wu A, Chavkin C. Agonist induced homologous desensitization of mu-opioid receptors mediated by G protein-coupled receptor kinases is dependent on agonist efficacy. Molecular Pharmacology. 54: 704-11. PMID 9765514  0.405
1997 Kovoor A, Nappey V, Kieffer BL, Chavkin C. Mu and delta opioid receptors are differentially desensitized by the coexpression of beta-adrenergic receptor kinase 2 and beta-arrestin 2 in xenopus oocytes. The Journal of Biological Chemistry. 272: 27605-11. PMID 9346897 DOI: 10.1074/Jbc.272.44.27605  0.402
1995 Kovoor A, Henry DJ, Chavkin C. Agonist-induced desensitization of the mu opioid receptor-coupled potassium channel (GIRK1). The Journal of Biological Chemistry. 270: 589-95. PMID 7822283 DOI: 10.1074/Jbc.270.2.589  0.394
1994 Henry D, Kovoor A, Chavkin C. Effects of treatment with kinase activators and inhibitors on mu and delta opioid receptor coupling to G-protein gated K+ channels in Xenopus oocytes Regulatory Peptides. 54: 157-158. DOI: 10.1016/0167-0115(94)90438-3  0.424
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