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Ravi Iyengar - Publications

Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Cellular signaling systems

231 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Toro CA, Hansen J, Siddiq MM, Johnson K, Zhao W, Azulai D, Das DK, Bauman W, Sebra R, Cai D, Iyengar R, Cardozo CP. The Human ApoE4 Variant Reduces Functional Recovery and Neuronal Sprouting After Incomplete Spinal Cord Injury in Male Mice. Frontiers in Cellular Neuroscience. 15: 626192. PMID 33679326 DOI: 10.3389/fncel.2021.626192  0.48
2021 de Boer IH, Alpers CE, Azeloglu EU, Balis UGJ, Barasch JM, Barisoni L, Blank KN, Bomback AS, Brown K, Dagher PC, Dighe AL, Eadon MT, El-Achkar TM, Gaut JP, Hacohen N, ... ... Iyengar R, et al. Rationale and design of the Kidney Precision Medicine Project. Kidney International. 99: 498-510. PMID 33637194 DOI: 10.1016/j.kint.2020.08.039  0.92
2020 Siddiq MM, Chan AT, Miorin L, Yadaw AS, Beaumont KG, Kehrer T, White KM, Cupic A, Tolentino RE, Hu B, Stern AD, Tavassoly I, Hansen J, Martinez P, Dubois N, ... ... Iyengar R, et al. Physiology of cardiomyocyte injury in COVID-19. Medrxiv : the Preprint Server For Health Sciences. PMID 33200140 DOI: 10.1101/2020.11.10.20229294  0.64
2020 El-Achkar TM, Eadon MT, Menon R, Lake BB, Sigdel TK, Alexandrov T, Parikh S, Zhang G, Dobib D, Dunn KW, Otto EA, Anderton CR, Carson JM, Luo J, Park C, ... ... Iyengar R, et al. A Multimodal and Integrated Approach to Interrogate Human Kidney Biopsies with Rigor and Reproducibility: Guidelines from the Kidney Precision Medicine Project. Physiological Genomics. PMID 33197228 DOI: 10.1152/physiolgenomics.00104.2020  0.92
2020 Yadaw AS, Li YC, Bose S, Iyengar R, Bunyavanich S, Pandey G. Clinical features of COVID-19 mortality: development and validation of a clinical prediction model. The Lancet. Digital Health. 2: e516-e525. PMID 32984797 DOI: 10.1016/S2589-7500(20)30217-X  0.44
2020 van Hasselt JGC, Rahman R, Hansen J, Stern A, Shim JV, Xiong Y, Pickard A, Jayaraman G, Hu B, Mahajan M, Gallo JM, Goldfarb J, Sobie EA, Birtwistle MR, Schlessinger A, ... ... Iyengar R, et al. Transcriptomic profiling of human cardiac cells predicts protein kinase inhibitor-associated cardiotoxicity. Nature Communications. 11: 4809. PMID 32968055 DOI: 10.1038/s41467-020-18396-7  0.92
2020 Ong E, Wang LL, Schaub J, O'Toole JF, Steck B, Rosenberg AZ, Dowd F, Hansen J, Barisoni L, Jain S, de Boer IH, Valerius MT, Waikar SS, Park C, Crawford DC, ... ... Iyengar R, et al. Modelling kidney disease using ontology: insights from the Kidney Precision Medicine Project. Nature Reviews. Nephrology. PMID 32939051 DOI: 10.1038/S41581-020-00335-W  0.48
2020 Yadaw AS, Li YC, Bose S, Iyengar R, Bunyavanich S, Pandey G. Clinical predictors of COVID-19 mortality. Medrxiv : the Preprint Server For Health Sciences. PMID 32511520 DOI: 10.1101/2020.05.19.20103036  0.44
2019 Mariottini C, Munari L, Gunzel E, Seco JM, Tzavaras N, Hansen J, Stern SA, Gao V, Aleyasin H, Sharma A, Azeloglu EU, Hodes GE, Russo SJ, Huff V, Birtwistle MR, ... ... Iyengar R, et al. Wilm's tumor 1 promotes memory flexibility. Nature Communications. 10: 3756. PMID 31434897 DOI: 10.1038/S41467-019-11781-X  0.92
2019 Cugno A, Bartol TM, Sejnowski TJ, Iyengar R, Rangamani P. Geometric principles of second messenger dynamics in dendritic spines. Scientific Reports. 9: 11676. PMID 31406140 DOI: 10.1038/S41598-019-48028-0  1
2019 He Y, Duncan WD, Cooper DJ, Hansen J, Iyengar R, Ong E, Walker K, Tibi O, Smith S, Serra LM, Zheng J, Sarntivijai S, Schürer S, O'Shea KS, Diehl AD. OSCI: standardized stem cell ontology representation and use cases for stem cell investigation. Bmc Bioinformatics. 20: 180. PMID 31272389 DOI: 10.1186/S12859-019-2723-7  0.48
2019 Hansen J, Galatioto J, Caescu CI, Arnaud P, Calizo RC, Spronck B, Murtada SI, Borkar R, Weinberg A, Azeloglu EU, Bintanel-Morcillo M, Gallo JM, Humphrey JD, Jondeau G, Boileau C, ... ... Iyengar R, et al. Systems pharmacology-based integration of human and mouse data for drug repurposing to treat thoracic aneurysms. Jci Insight. 4. PMID 31167969 DOI: 10.1172/Jci.Insight.127652  0.92
2019 Tavassoly I, Hu Y, Zhao S, Mariottini C, Boran A, Chen Y, Li L, Tolentino RE, Jayaraman G, Goldfarb J, Gallo J, Iyengar R. Genomic signatures defining responsiveness to allopurinol and combination therapy for lung cancer identified by systems therapeutics analyses. Molecular Oncology. PMID 31116490 DOI: 10.1002/1878-0261.12521  1
2019 Yadaw AS, Siddiq MM, Rabinovich V, Tolentino R, Hansen J, Iyengar R. Dynamic balance between vesicle transport and microtubule growth enables neurite outgrowth. Plos Computational Biology. 15: e1006877. PMID 31042702 DOI: 10.1371/journal.pcbi.1006877  0.48
2018 Tavassoly I, Goldfarb J, Iyengar R. Systems biology primer: the basic methods and approaches. Essays in Biochemistry. PMID 30287586 DOI: 10.1042/Ebc20180003  0.64
2018 Koch RJ, Barrette AM, Stern AD, Hu B, Bouhaddou M, Azeloglu EU, Iyengar R, Birtwistle MR. Validating Antibodies for Quantitative Western Blot Measurements with Microwestern Array. Scientific Reports. 8: 11329. PMID 30054510 DOI: 10.1038/S41598-018-29436-0  0.92
2018 Galatioto J, Caescu CI, Hansen J, Cook J, Miramontes I, Iyengar R, Ramirez F. Cell Type-Specific Contributions of the Angiotensin II Type 1a Receptor to Aorta Homeostasis and Aneurysmal Disease. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 29371244 DOI: 10.1161/ATVBAHA.117.310609  0.48
2018 Keenan AB, Jenkins SL, Jagodnik KM, Koplev S, He E, Torre D, Wang Z, Dohlman AB, Silverstein MC, Lachmann A, Kuleshov MV, Ma'ayan A, Stathias V, Terryn R, Cooper D, ... ... Iyengar R, et al. The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations. Cell Systems. 6: 13-24. PMID 29199020 DOI: 10.1016/J.Cels.2017.11.001  0.92
2017 Hansen J, Meretzky D, Woldesenbet S, Stolovitzky G, Iyengar R. A flexible ontology for inference of emergent whole cell function from relationships between subcellular processes. Scientific Reports. 7: 17689. PMID 29255142 DOI: 10.1038/S41598-017-16627-4  0.48
2017 Ron A, Azeloglu EU, Calizo RC, Hu M, Bhattacharya S, Chen Y, Jayaraman G, Lee S, Neves-Zaph SR, Li H, Gordon RE, He JC, Hone JC, Iyengar R. Cell shape information is transduced through tension-independent mechanisms. Nature Communications. 8: 2145. PMID 29247198 DOI: 10.1038/S41467-017-02218-4  0.92
2017 Xiong Y, Soumillon M, Wu J, Hansen J, Hu B, van Hasselt JGC, Jayaraman G, Lim R, Bouhaddou M, Ornelas L, Bochicchio J, Lenaeus L, Stocksdale J, Shim J, Gomez E, ... ... Iyengar R, et al. A Comparison of mRNA Sequencing with Random Primed and 3'-Directed Libraries. Scientific Reports. 7: 14626. PMID 29116112 DOI: 10.1038/S41598-017-14892-X  0.92
2017 Falkenberg CV, Azeloglu EU, Stothers M, Deerinck TJ, Chen Y, He JC, Ellisman MH, Hone JC, Iyengar R, Loew LM. Fragility of foot process morphology in kidney podocytes arises from chaotic spatial propagation of cytoskeletal instability. Plos Computational Biology. 13: e1005433. PMID 28301477 DOI: 10.1371/Journal.Pcbi.1005433  0.92
2017 Hu M, Azeloglu EU, Ron A, Tran-Ba KH, Calizo RC, Tavassoly I, Bhattacharya S, Jayaraman G, Chen Y, Rabinovich V, Iyengar R, Hone JC, He JC, Kaufman LJ. A biomimetic gelatin-based platform elicits a pro-differentiation effect on podocytes through mechanotransduction. Scientific Reports. 7: 43934. PMID 28262745 DOI: 10.1038/Srep43934  0.92
2017 Stillitano F, Hansen J, Kong CW, Karakikes I, Funck-Brentano C, Geng L, Scott S, Reynier S, Wu M, Valogne Y, Desseaux C, Salem JE, Jeziorowska D, Zahr N, Li R, ... Iyengar R, et al. Modeling susceptibility to drug-induced long QT with a panel of subject-specific induced pluripotent stem cells. Elife. 6. PMID 28134617 DOI: 10.7554/Elife.19406  0.48
2016 Andrews BJ, Marian Walhout AJ, Iyengar R, Apweiler R, Ardlie K, Azeloglu EU, Birtwistle MR, Coon JJ, Dolinski K, Fan T, FitzGerald GA, Gavin AC, Gingras AC, Gough NR, Hoffmann A, et al. Quantitative human cell encyclopedia Science Signaling. 9. DOI: 10.1126/scisignal.aah4406  1
2015 Iyengar R. Can intracellular cAMP dynamics enable scalable computation? Frontiers in Cellular Neuroscience. 9: 112. PMID 25870541 DOI: 10.3389/fncel.2015.00112  1
2015 Azeloglu EU, Iyengar R. Good practices for building dynamical models in systems biology. Science Signaling. 8: fs8. PMID 25852187 DOI: 10.1126/scisignal.aab0880  1
2015 Azeloglu EU, Iyengar R. Signaling networks: information flow, computation, and decision making. Cold Spring Harbor Perspectives in Biology. 7: a005934. PMID 25833842 DOI: 10.1101/cshperspect.a005934  1
2015 Iyengar RS, Sekhar C, Karimabad AS, Haghighat F, Zhu K. A comparative study of leakage characteristics between an under floor air distribution system and an over head air distribution system International Journal of Ventilation. 14: 1-10.  0.32
2014 Rangamani P, Xiong GY, Iyengar R. Multiscale modeling of cell shape from the actin cytoskeleton. Progress in Molecular Biology and Translational Science. 123: 143-67. PMID 24560144 DOI: 10.1016/B978-0-12-397897-4.00002-4  1
2014 Azeloglu EU, Hardy SV, Eungdamrong NJ, Chen Y, Jayaraman G, Chuang PY, Fang W, Xiong H, Neves SR, Jain MR, Li H, Ma'ayan A, Gordon RE, He JC, Iyengar R. Interconnected network motifs control podocyte morphology and kidney function. Science Signaling. 7: ra12. PMID 24497609 DOI: 10.1126/Scisignal.2004621  1
2014 Karakikes I, Senyei GD, Hansen J, Kong CW, Azeloglu EU, Stillitano F, Lieu DK, Wang J, Ren L, Hulot JS, Iyengar R, Li RA, Hajjar RJ. Small molecule-mediated directed differentiation of human embryonic stem cells toward ventricular cardiomyocytes. Stem Cells Translational Medicine. 3: 18-31. PMID 24324277 DOI: 10.5966/Sctm.2013-0110  1
2014 Saber EM, Iyengar R, Mast M, Meggers F, Tham KW, Leibundgut H. Thermal comfort and IAQ analysis of a decentralized DOAS system coupled with radiant cooling for the tropics Building and Environment. 82: 361-370. DOI: 10.1016/j.buildenv.2014.09.001  0.32
2013 Iyengar R. Complex diseases require complex therapies. Embo Reports. 14: 1039-42. PMID 24232184 DOI: 10.1038/embor.2013.177  1
2013 Zhao S, Nishimura T, Chen Y, Azeloglu EU, Gottesman O, Giannarelli C, Zafar MU, Benard L, Badimon JJ, Hajjar RJ, Goldfarb J, Iyengar R. Systems pharmacology of adverse event mitigation by drug combinations. Science Translational Medicine. 5: 206ra140. PMID 24107779 DOI: 10.1126/Scitranslmed.3006548  1
2013 Rangamani P, Lipshtat A, Azeloglu EU, Calizo RC, Hu M, Ghassemi S, Hone J, Scarlata S, Neves SR, Iyengar R. Decoding information in cell shape. Cell. 154: 1356-69. PMID 24034255 DOI: 10.1016/J.Cell.2013.08.026  1
2013 Hansen J, Iyengar R. Computation as the mechanistic bridge between precision medicine and systems therapeutics. Clinical Pharmacology and Therapeutics. 93: 117-28. PMID 23212109 DOI: 10.1038/clpt.2012.199  1
2013 Bruelisauer M, Chen KW, Iyengar R, Leibundgut H, Li C, Li M, Mast M, Meggers F, Miller C, Rossi D, Saber EM, Schlueter A, Tham KW. BubbleZERO-design, construction and operation of a transportable research laboratory for low exergy building system evaluation in the tropics Energies. 6: 4551-4571. DOI: 10.3390/en6094551  0.32
2013 Iyengar RS, Saber E, Meggers F, Leibundgut H. The feasibility of performing high-temperature radiant cooling in tropical buildings when coupled with a decentralized ventilation system Hvac and R Research. 19: 992-1000. DOI: 10.1080/10789669.2013.826065  0.32
2013 Mariottini C, Iyengar R. System Biology of Cell Signaling Handbook of Systems Biology. 311-327. DOI: 10.1016/B978-0-12-385944-0.00016-2  1
2012 Boran AD, Seco J, Jayaraman V, Jayaraman G, Zhao S, Reddy S, Chen Y, Iyengar R. A potential peptide therapeutic derived from the juxtamembrane domain of the epidermal growth factor receptor. Plos One. 7: e49702. PMID 23166750 DOI: 10.1371/Journal.Pone.0049702  1
2012 Iyengar R, Zhao S, Chung SW, Mager DE, Gallo JM. Merging systems biology with pharmacodynamics. Science Translational Medicine. 4: 126ps7. PMID 22440734 DOI: 10.1126/Scitranslmed.3003563  1
2012 Hwangpo TA, Jordan JD, Premsrirut PK, Jayamaran G, Licht JD, Iyengar R, Neves SR. G Protein-regulated inducer of neurite outgrowth (GRIN) modulates Sprouty protein repression of mitogen-activated protein kinase (MAPK) activation by growth factor stimulation. The Journal of Biological Chemistry. 287: 13674-85. PMID 22383529 DOI: 10.1074/Jbc.M111.320705  1
2012 Zhao S, Iyengar R. Systems pharmacology: network analysis to identify multiscale mechanisms of drug action. Annual Review of Pharmacology and Toxicology. 52: 505-21. PMID 22235860 DOI: 10.1146/Annurev-Pharmtox-010611-134520  1
2012 He JC, Chuang PY, Ma'ayan A, Iyengar R. Systems biology of kidney diseases. Kidney International. 81: 22-39. PMID 21881558 DOI: 10.1038/Ki.2011.314  1
2012 Azeloglu EU, Stothers M, Deerinck TJ, Falkenberg C, Chen Y, He JC, Hone JC, Loew LM, Ellisman MH, Iyengar R. 3-D quantitative microanatomy of rat kidney podocytes as determined by serial block-face scanning electron microscopy Asme 2012 Summer Bioengineering Conference, Sbc 2012. 1213-1214. DOI: 10.1115/SBC2012-80650  1
2012 Lambrecht A, Seim K, Vilcassim N, Cheema A, Chen Y, Crawford GS, Hosanagar K, Iyengar R, Koenigsberg O, Lee R, Miravete EJ, Sahin O. Price discrimination in service industries Marketing Letters. 23: 423-438. DOI: 10.1007/S11002-012-9187-0  0.4
2012 Iyengar RS, Cirillo E, Kaushik V, Vignesh N, Jayaraman V, Sekhar C. High performance building design strategy to achieve resilience towards climate change 10th International Conference On Healthy Buildings 2012. 2: 919-924.  0.32
2012 Iyengar RS, Meggers F, Leibundgut H. A new approach to cool buildings in the tropics: Low exergy mechanism 10th International Conference On Healthy Buildings 2012. 3: 2211-2212.  0.32
2012 Iyengar R, Meggers F. The win-win opportunities for optimizing building energy consumption and IEQ 10th International Conference On Healthy Buildings 2012. 3: 2161-2162.  0.32
2011 Hansen J, Zhao S, Iyengar R. Systems pharmacology of complex diseases. Annals of the New York Academy of Sciences. 1245: E1-5. PMID 22417173 DOI: 10.1111/J.1749-6632.2011.06382.X  1
2011 Mazloom AR, Dannenfelser R, Clark NR, Grigoryan AV, Linder KM, Cardozo TJ, Bond JC, Boran AD, Iyengar R, Malovannaya A, Lanz RB, Ma'ayan A. Recovering protein-protein and domain-domain interactions from aggregation of IP-MS proteomics of coregulator complexes. Plos Computational Biology. 7: e1002319. PMID 22219718 DOI: 10.1371/Journal.Pcbi.1002319  1
2011 Sobie EA, Lee YS, Jenkins SL, Iyengar R. Systems biology--biomedical modeling. Science Signaling. 4: tr2. PMID 21917716 DOI: 10.1126/Scisignal.2001989  1
2011 Boran AD, Chen Y, Iyengar R. Identification of new Gβγ interaction sites in adenylyl cyclase 2. Cellular Signalling. 23: 1489-95. PMID 21596131 DOI: 10.1016/j.cellsig.2011.05.002  1
2011 Rangamani P, Fardin MA, Xiong Y, Lipshtat A, Rossier O, Sheetz MP, Iyengar R. Signaling network triggers and membrane physical properties control the actin cytoskeleton-driven isotropic phase of cell spreading. Biophysical Journal. 100: 845-57. PMID 21320428 DOI: 10.1016/J.Bpj.2010.12.3732  1
2011 Michailidis IE, Rusinova R, Georgakopoulos A, Chen Y, Iyengar R, Robakis NK, Logothetis DE, Baki L. Phosphatidylinositol-4,5-bisphosphate regulates epidermal growth factor receptor activation. PflüGers Archiv : European Journal of Physiology. 461: 387-97. PMID 21107857 DOI: 10.1007/S00424-010-0904-3  1
2011 Berger SI, Iyengar R. Role of systems pharmacology in understanding drug adverse events. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 3: 129-35. PMID 20803507 DOI: 10.1002/Wsbm.114  1
2010 Fardin MA, Rossier OM, Rangamani P, Avigan PD, Gauthier NC, Vonnegut W, Mathur A, Hone J, Iyengar R, Sheetz MP. Cell spreading as a hydrodynamic process. Soft Matter. 6: 4788-4799. PMID 23908673 DOI: 10.1039/C0Sm00252F  1
2010 Pigati L, Yaddanapudi SC, Iyengar R, Kim DJ, Hearn SA, Danforth D, Hastings ML, Duelli DM. Selective release of microRNA species from normal and malignant mammary epithelial cells. Plos One. 5: e13515. PMID 20976003 DOI: 10.1371/journal.pone.0013515  0.44
2010 Boran AD, Iyengar R. Systems pharmacology. The Mount Sinai Journal of Medicine, New York. 77: 333-44. PMID 20687178 DOI: 10.1002/msj.20191  1
2010 Iyengar R. Drug discovery in academic settings. The Mount Sinai Journal of Medicine, New York. 77: 325-6. PMID 20687176 DOI: 10.1002/msj.20190  1
2010 Sobie EA, Jenkins SL, Iyengar R, Krulwich TA. Training in systems pharmacology: predoctoral program in pharmacology and systems biology at Mount Sinai School of Medicine. Clinical Pharmacology and Therapeutics. 88: 19-22. PMID 20562890 DOI: 10.1038/Clpt.2010.41  1
2010 Xiong Y, Rangamani P, Fardin MA, Lipshtat A, Dubin-Thaler B, Rossier O, Sheetz MP, Iyengar R. Mechanisms controlling cell size and shape during isotropic cell spreading. Biophysical Journal. 98: 2136-46. PMID 20483321 DOI: 10.1016/J.Bpj.2010.01.059  1
2010 Boran AD, Iyengar R. Systems approaches to polypharmacology and drug discovery. Current Opinion in Drug Discovery & Development. 13: 297-309. PMID 20443163  1
2010 Berger SI, Ma'ayan A, Iyengar R. Systems pharmacology of arrhythmias. Science Signaling. 3: ra30. PMID 20407125 DOI: 10.1126/Scisignal.2000723  1
2010 Lipshtat A, Jayaraman G, He JC, Iyengar R. Design of versatile biochemical switches that respond to amplitude, duration, and spatial cues. Proceedings of the National Academy of Sciences of the United States of America. 107: 1247-52. PMID 20080566 DOI: 10.1073/pnas.0908647107  1
2010 Zorina Y, Iyengar R, Bromberg KD. Cannabinoid 1 receptor and interleukin-6 receptor together induce integration of protein kinase and transcription factor signaling to trigger neurite outgrowth. The Journal of Biological Chemistry. 285: 1358-70. PMID 19861414 DOI: 10.1074/Jbc.M109.049841  1
2010 Berger SI, Iyengar R, Van Hook AM. Science Signaling podcast: 20 April 2010 Science Signaling. 3: pc8. DOI: 10.1126/Scisignal.3118Pc8  1
2010 Zorina Y, Iyengar R, Bromberg KD. Effectors of gαo Handbook of Cell Signaling, 2/E. 2: 1655-1663. DOI: 10.1016/B978-0-12-374145-5.00203-5  1
2009 Cordeddu V, Di Schiavi E, Pennacchio LA, Ma'ayan A, Sarkozy A, Fodale V, Cecchetti S, Cardinale A, Martin J, Schackwitz W, Lipzen A, Zampino G, Mazzanti L, Digilio MC, Martinelli S, ... ... Iyengar R, et al. Mutation of SHOC2 promotes aberrant protein N-myristoylation and causes Noonan-like syndrome with loose anagen hair. Nature Genetics. 41: 1022-6. PMID 19684605 DOI: 10.1038/ng.425  1
2009 Berger SI, Iyengar R. Network analyses in systems pharmacology. Bioinformatics (Oxford, England). 25: 2466-72. PMID 19648136 DOI: 10.1093/Bioinformatics/Btp465  1
2009 Feng X, Lu TC, Chuang PY, Fang W, Ratnam K, Xiong H, Ouyang X, Shen Y, Levy DE, Hyink D, Klotman M, D'Agati V, Iyengar R, Klotman PE, He JC. Reduction of Stat3 activity attenuates HIV-induced kidney injury. Journal of the American Society of Nephrology : Jasn. 20: 2138-46. PMID 19608706 DOI: 10.1681/Asn.2008080879  1
2009 Abul-Husn NS, Bushlin I, Morón JA, Jenkins SL, Dolios G, Wang R, Iyengar R, Ma'ayan A, Devi LA. Systems approach to explore components and interactions in the presynapse. Proteomics. 9: 3303-15. PMID 19562802 DOI: 10.1002/Pmic.200800767  1
2009 Wist AD, Berger SI, Iyengar R. Systems pharmacology and genome medicine: a future perspective. Genome Medicine. 1: 11. PMID 19348698 DOI: 10.1186/Gm11  1
2009 Lipshtat A, Neves SR, Iyengar R. Specification of spatial relationships in directed graphs of cell signaling networks. Annals of the New York Academy of Sciences. 1158: 44-56. PMID 19348631 DOI: 10.1111/J.1749-6632.2008.03748.X  1
2009 Ma'ayan A, Jenkins SL, Barash A, Iyengar R. Neuro2A differentiation by Galphai/o pathway. Science Signaling. 2: cm1. PMID 19155528 DOI: 10.1126/Scisignal.254Cm1  1
2009 Ma'ayan A, Jenkins SL, Webb RL, Berger SI, Purushothaman SP, Abul-Husn NS, Posner JM, Flores T, Iyengar R. SNAVI: Desktop application for analysis and visualization of large-scale signaling networks. Bmc Systems Biology. 3: 10. PMID 19154595 DOI: 10.1186/1752-0509-3-10  1
2009 Neves SR, Iyengar R. Models of spatially restricted biochemical reaction systems. The Journal of Biological Chemistry. 284: 5445-9. PMID 18940805 DOI: 10.1074/Jbc.R800058200  1
2009 Iyengar R. Computational biochemistry: systems biology minireview series. The Journal of Biological Chemistry. 284: 5425-6. PMID 18940804 DOI: 10.1074/jbc.R800066200  1
2008 Ma'ayan A, Cecchi GA, Wagner J, Rao AR, Iyengar R, Stolovitzky G. Ordered cyclic motifs contribute to dynamic stability in biological and engineered networks. Proceedings of the National Academy of Sciences of the United States of America. 105: 19235-40. PMID 19033453 DOI: 10.1073/Pnas.0805344105  1
2008 Rangamani P, Iyengar R. Modelling cellular signalling systems. Essays in Biochemistry. 45: 83-94. PMID 18793125 DOI: 10.1042/Bse0450083  1
2008 Lu TC, Wang Z, Feng X, Chuang P, Fang W, Chen Y, Neves S, Maayan A, Xiong H, Liu Y, Iyengar R, Klotman PE, He JC. Retinoic acid utilizes CREB and USF1 in a transcriptional feed-forward loop in order to stimulate MKP1 expression in human immunodeficiency virus-infected podocytes. Molecular and Cellular Biology. 28: 5785-94. PMID 18625721 DOI: 10.1128/Mcb.00245-08  1
2008 Ma'ayan A, Lipshtat A, Iyengar R, Sontag ED. Proximity of intracellular regulatory networks to monotone systems. Iet Systems Biology. 2: 103-12. PMID 18537452 DOI: 10.1049/Iet-Syb:20070036  1
2008 Bromberg KD, Iyengar R, He JC. Regulation of neurite outgrowth by G(i/o) signaling pathways. Frontiers in Bioscience : a Journal and Virtual Library. 13: 4544-57. PMID 18508528 DOI: 10.2741/3022  0.72
2008 Bromberg KD, Ma'ayan A, Neves SR, Iyengar R. Design logic of a cannabinoid receptor signaling network that triggers neurite outgrowth. Science (New York, N.Y.). 320: 903-9. PMID 18487186 DOI: 10.1126/Science.1152662  1
2008 Neves SR, Tsokas P, Sarkar A, Grace EA, Rangamani P, Taubenfeld SM, Alberini CM, Schaff JC, Blitzer RD, Moraru II, Iyengar R. Cell shape and negative links in regulatory motifs together control spatial information flow in signaling networks. Cell. 133: 666-80. PMID 18485874 DOI: 10.1016/J.Cell.2008.04.025  1
2008 Korgaonkar SN, Feng X, Ross MD, Lu TC, D'Agati V, Iyengar R, Klotman PE, He JC. HIV-1 upregulates VEGF in podocytes. Journal of the American Society of Nephrology : Jasn. 19: 877-83. PMID 18443354 DOI: 10.1681/Asn.2007050629  1
2008 Pagano M, Jordan JD, Neves SR, Nguyen T, Iyengar R. Galphao/i-stimulated proteosomal degradation of RGS20: a mechanism for temporal integration of Gs and Gi pathways. Cellular Signalling. 20: 1190-7. PMID 18407463 DOI: 10.1016/J.Cellsig.2008.02.008  1
2008 Jenkins SL, Iyengar R, Diverse-Pierluissi MA, Chan AM, Devi LA, Sobie EA, Ting AT, Weinstein DC. Teaching resources. Using web-based discussion forums as a model of the peer-review process and a tool for assessment. Science Signaling. 1: tr2. PMID 18323015 DOI: 10.1126/Stke.19Tr2  1
2008 Iyengar R, Diverse-Pierluissi MA, Jenkins SL, Chan AM, Devi LA, Sobie EA, Ting AT, Weinstein DC. Inquiry learning. Integrating content detail and critical reasoning by peer review. Science (New York, N.Y.). 319: 1189-90. PMID 18309063 DOI: 10.1126/Science.1149875  1
2008 Iyengar R. Teaching resource. Quantitative models of mammalian cell signaling pathways. Science Signaling. 1: tr1. PMID 18290302 DOI: 10.1126/stke.17tr1  1
2008 Lu TC, He JC, Wang ZH, Feng X, Fukumi-Tominaga T, Chen N, Xu J, Iyengar R, Klotman PE. HIV-1 Nef disrupts the podocyte actin cytoskeleton by interacting with diaphanous interacting protein. The Journal of Biological Chemistry. 283: 8173-82. PMID 18234668 DOI: 10.1074/Jbc.M708920200  1
2008 Lipshtat A, Purushothaman SP, Iyengar R, Ma'ayan A. Functions of bifans in context of multiple regulatory motifs in signaling networks. Biophysical Journal. 94: 2566-79. PMID 18178648 DOI: 10.1529/biophysj.107.116673  1
2007 Berger SI, Iyengar R, Ma'ayan A. AVIS: AJAX viewer of interactive signaling networks. Bioinformatics (Oxford, England). 23: 2803-5. PMID 17855420 DOI: 10.1093/Bioinformatics/Btm444  1
2007 Zaidel-Bar R, Itzkovitz S, Ma'ayan A, Iyengar R, Geiger B. Functional atlas of the integrin adhesome. Nature Cell Biology. 9: 858-67. PMID 17671451 DOI: 10.1038/Ncb0807-858  1
2007 Tsokas P, Ma T, Iyengar R, Landau EM, Blitzer RD. Mitogen-activated protein kinase upregulates the dendritic translation machinery in long-term potentiation by controlling the mammalian target of rapamycin pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 5885-94. PMID 17537959 DOI: 10.1523/Jneurosci.4548-06.2007  1
2007 Ma'ayan A, Jenkins SL, Goldfarb J, Iyengar R. Network analysis of FDA approved drugs and their targets. The Mount Sinai Journal of Medicine, New York. 74: 27-32. PMID 17516560 DOI: 10.1002/Msj.20002  1
2007 Rangamani P, Iyengar R. Modelling spatio-temporal interactions within the cell. Journal of Biosciences. 32: 157-67. PMID 17426388 DOI: 10.1007/S12038-007-0014-3  1
2007 Aaronson DS, Muller M, Neves SR, Chung WC, Jayaram G, Iyengar R, Ram PT. An androgen-IL-6-Stat3 autocrine loop re-routes EGF signal in prostate cancer cells. Molecular and Cellular Endocrinology. 270: 50-6. PMID 17374439 DOI: 10.1016/J.Mce.2007.02.006  1
2007 He JC, Lu TC, Fleet M, Sunamoto M, Husain M, Fang W, Neves S, Chen Y, Shankland S, Iyengar R, Klotman PE. Retinoic acid inhibits HIV-1-induced podocyte proliferation through the cAMP pathway. Journal of the American Society of Nephrology : Jasn. 18: 93-102. PMID 17182884 DOI: 10.1681/Asn.2006070727  1
2007 Eungdamrong NJ, Iyengar R. Compartment-specific feedback loop and regulated trafficking can result in sustained activation of Ras at the Golgi. Biophysical Journal. 92: 808-15. PMID 17098795 DOI: 10.1529/biophysj.106.093104  0.36
2006 He JC, Neves SR, Jordan JD, Iyengar R. Role of the Go/i signaling network in the regulation of neurite outgrowth. Canadian Journal of Physiology and Pharmacology. 84: 687-94. PMID 16998532 DOI: 10.1139/y06-025  1
2006 Ma'ayan A, Lipshtat A, Iyengar R. Topology of resultant networks shaped by evolutionary pressure. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 73: 061912. PMID 16906869 DOI: 10.1103/PhysRevE.73.061912  1
2006 Ma'ayan A, Gardiner K, Iyengar R. The cognitive phenotype of Down syndrome: insights from intracellular network analysis. Neurorx : the Journal of the American Society For Experimental Neurotherapeutics. 3: 396-406. PMID 16815222 DOI: 10.1016/J.Nurx.2006.05.036  1
2006 Ma'ayan A, Iyengar R. From components to regulatory motifs in signalling networks. Briefings in Functional Genomics & Proteomics. 5: 57-61. PMID 16769680 DOI: 10.1093/Bfgp/Ell004  1
2005 Ma'ayan A, Jenkins SL, Neves S, Hasseldine A, Grace E, Dubin-Thaler B, Eungdamrong NJ, Weng G, Ram PT, Rice JJ, Kershenbaum A, Stolovitzky GA, Blitzer RD, Iyengar R. Formation of regulatory patterns during signal propagation in a Mammalian cellular network. Science (New York, N.Y.). 309: 1078-83. PMID 16099987 DOI: 10.1126/Science.1108876  1
2005 He JC, Gomes I, Nguyen T, Jayaram G, Ram PT, Devi LA, Iyengar R. The G alpha(o/i)-coupled cannabinoid receptor-mediated neurite outgrowth involves Rap regulation of Src and Stat3. The Journal of Biological Chemistry. 280: 33426-34. PMID 16046413 DOI: 10.1074/Jbc.M502812200  0.56
2005 Tsokas P, Grace EA, Chan P, Ma T, Sealfon SC, Iyengar R, Landau EM, Blitzer RD. Local protein synthesis mediates a rapid increase in dendritic elongation factor 1A after induction of late long-term potentiation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 5833-43. PMID 15958750 DOI: 10.1523/Jneurosci.0599-05.2005  1
2005 Ma'ayan A, Blitzer RD, Iyengar R. Toward predictive models of mammalian cells. Annual Review of Biophysics and Biomolecular Structure. 34: 319-49. PMID 15869393 DOI: 10.1146/Annurev.Biophys.34.040204.144415  1
2005 Iyengar R. Teaching resources. Structure of G-protein-coupled receptors and G proteins. Science's Stke : Signal Transduction Knowledge Environment. 2005: tr10. PMID 15784881 DOI: 10.1126/stke.2762005tr10  1
2005 Iyengar R. Teaching resources. Introduction: Overview of pathways and networks and GPCR signaling. Science's Stke : Signal Transduction Knowledge Environment. 2005: tr4. PMID 15701895 DOI: 10.1126/stke.2702005tr4  1
2005 Iyengar R, Diverse-Pierluissi M, Weinstein D, Devi LA. Teaching resources. Cell signaling systems: a course for graduate students. Science's Stke : Signal Transduction Knowledge Environment. 2005: tr3. PMID 15687508 DOI: 10.1126/stke.2692005tr3  1
2005 Jordan JD, He JC, Eungdamrong NJ, Gomes I, Ali W, Nguyen T, Bivona TG, Philips MR, Devi LA, Iyengar R. Cannabinoid receptor-induced neurite outgrowth is mediated by Rap1 activation through G(alpha)o/i-triggered proteasomal degradation of Rap1GAPII. The Journal of Biological Chemistry. 280: 11413-21. PMID 15657046 DOI: 10.1074/Jbc.M411521200  1
2005 Blitzer RD, Iyengar R, Landau EM. Postsynaptic signaling networks: cellular cogwheels underlying long-term plasticity. Biological Psychiatry. 57: 113-9. PMID 15652868 DOI: 10.1016/J.Biopsych.2004.02.031  1
2004 Eungdamrong NJ, Iyengar R. Computational approaches for modeling regulatory cellular networks. Trends in Cell Biology. 14: 661-9. PMID 15564042 DOI: 10.1016/j.tcb.2004.10.007  0.36
2004 He JC, Husain M, Sunamoto M, D'Agati VD, Klotman ME, Iyengar R, Klotman PE. Nef stimulates proliferation of glomerular podocytes through activation of Src-dependent Stat3 and MAPK1,2 pathways. The Journal of Clinical Investigation. 114: 643-51. PMID 15343382 DOI: 10.1172/Jci21004  1
2004 Campagne F, Neves S, Chang CW, Skrabanek L, Ram PT, Iyengar R, Weinstein H. Quantitative information management for the biochemical computation of cellular networks. Science's Stke : Signal Transduction Knowledge Environment. 2004: pl11. PMID 15340175 DOI: 10.1126/Stke.2482004Pl11  1
2004 Eungdamrong NJ, Iyengar R. Modeling cell signaling networks. Biology of the Cell / Under the Auspices of the European Cell Biology Organization. 96: 355-62. PMID 15207904 DOI: 10.1016/j.biolcel.2004.03.004  0.36
2004 Yoo B, Iyengar R, Chen Y. Functional analysis of the interface regions involved in interactions between the central cytoplasmic loop and the C-terminal tail of adenylyl cyclase. The Journal of Biological Chemistry. 279: 13925-33. PMID 14722077 DOI: 10.1074/jbc.M314334200  0.4
2003 Buck E, Iyengar R. Organization and functions of interacting domains for signaling by protein-protein interactions. Science's Stke : Signal Transduction Knowledge Environment. 2003: re14. PMID 14625370 DOI: 10.1126/Stke.2092003Re14  1
2002 Neves SR, Iyengar R. Modeling of signaling networks. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 24: 1110-7. PMID 12447976 DOI: 10.1002/Bies.1154  1
2002 Obrink B, Sawa H, Scheffrahn I, Singer BB, Sigmundsson K, Sundberg U, Heymann R, Beauchemin N, Weng G, Ram P, Iyengar R. Computational analysis of isoform-specific signal regulation by CEACAM1-A cell adhesion molecule expressed in PC12 cells. Annals of the New York Academy of Sciences. 971: 597-607. PMID 12438192 DOI: 10.1111/J.1749-6632.2002.Tb04536.X  0.68
2002 Buck E, Schatz P, Scarlata S, Iyengar R. Role of dynamic interactions in effective signal transfer for Gbeta stimulation of phospholipase C-beta 2. The Journal of Biological Chemistry. 277: 49707-15. PMID 12388553 DOI: 10.1074/Jbc.M205553200  0.36
2002 Li G, Iyengar R. Calpain as an effector of the Gq signaling pathway for inhibition of Wnt/beta -catenin-regulated cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 99: 13254-9. PMID 12239346 DOI: 10.1073/Pnas.202355799  1
2002 Bhalla US, Ram PT, Iyengar R. MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network. Science (New York, N.Y.). 297: 1018-23. PMID 12169734 DOI: 10.1126/science.1068873  1
2002 Neves SR, Ram PT, Iyengar R. G protein pathways. Science (New York, N.Y.). 296: 1636-9. PMID 12040175 DOI: 10.1126/Science.1071550  1
2002 Santore TA, Chen Y, Smit MJ, Iyengar R. Adenovirus-directed expression of Q227L-G alpha(s) inhibits growth of established tumors of later-stage human breast cancer cells in athymic mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 1671-6. PMID 11805301 DOI: 10.1073/Pnas.032661999  1
2002 Buck E, Iyengar R. Use of peptide probes to determine function of interaction sites in G protein interactions with effectors. Methods in Enzymology. 344: 513-21. PMID 11771407 DOI: 10.1016/S0076-6879(02)44737-4  1
2002 Brown GP, Iyengar R. Expression of adenovirus-directed expression of activated G alpha s in rat hippocampal slices. Methods in Enzymology. 344: 343-9. PMID 11771395 DOI: 10.1016/S0076-6879(02)44726-X  1
2002 Santore TA, Iyengar R. Construction of replication defective adenovirus that expresses mutant G alpha s Q227L. Methods in Enzymology. 344: 328-43. PMID 11771394 DOI: 10.1016/S0076-6879(02)44725-8  1
2002 Jordan JD, Iyengar R. Identification of putative direct effectors for G alpha o, using yeast two-hybrid method. Methods in Enzymology. 345: 140-9. PMID 11665601 DOI: 10.1016/S0076-6879(02)45013-6  1
2001 Bhalla US, Iyengar R. Robustness of the bistable behavior of a biological signaling feedback loop. Chaos (Woodbury, N.Y.). 11: 221-226. PMID 12779455 DOI: 10.1063/1.1350440  1
2001 Chen Y, Yoo B, Lee JB, Weng G, Iyengar R. The signal transfer regions of G alpha(s). The Journal of Biological Chemistry. 276: 45751-4. PMID 11579096 DOI: 10.1074/jbc.M107191200  0.68
2001 Giovannini MG, Blitzer RD, Wong T, Asoma K, Tsokas P, Morrison JH, Iyengar R, Landau EM. Mitogen-activated protein kinase regulates early phosphorylation and delayed expression of Ca2+/calmodulin-dependent protein kinase II in long-term potentiation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 7053-62. PMID 11549715 DOI: 10.1523/Jneurosci.21-18-07053.2001  1
2001 Bhalla US, Iyengar R. Functional modules in biological signalling networks. Novartis Foundation Symposium. 239: 4-13; discussion 13-. PMID 11529315 DOI: 10.1002/0470846674.Ch2  1
2001 Ram PT, Iyengar R. G protein coupled receptor signaling through the Src and Stat3 pathway: role in proliferation and transformation. Oncogene. 20: 1601-6. PMID 11313907 DOI: 10.1038/sj.onc.1204186  1
2001 Holness W, Santore TA, Brown GP, Fallon JT, Taubman MB, Iyengar R. Expression of Q227L-Galpha(s) inhibits intimal vessel wall hyperplasia after balloon injury. Proceedings of the National Academy of Sciences of the United States of America. 98: 1288-93. PMID 11158632 DOI: 10.1073/Pnas.98.3.1288  1
2000 Jordan JD, Landau EM, Iyengar R. Signaling networks: the origins of cellular multitasking. Cell. 103: 193-200. PMID 11057893 DOI: 10.1016/S0092-8674(00)00112-4  1
2000 Brown GP, Blitzer RD, Connor JH, Wong T, Shenolikar S, Iyengar R, Landau EM. Long-term potentiation induced by theta frequency stimulation is regulated by a protein phosphatase-1-operated gate. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 7880-7. PMID 11050107  1
2000 Ram PT, Horvath CM, Iyengar R. Stat3-mediated transformation of NIH-3T3 cells by the constitutively active Q205L Galphao protein. Science (New York, N.Y.). 287: 142-4. PMID 10615050 DOI: 10.1126/Science.287.5450.142  0.56
1999 Jordan JD, Carey KD, Stork PJ, Iyengar R. Modulation of rap activity by direct interaction of Galpha(o) with Rap1 GTPase-activating protein. The Journal of Biological Chemistry. 274: 21507-10. PMID 10419452 DOI: 10.1074/jbc.274.31.21507  1
1999 Weng G, Bhalla US, Iyengar R. Complexity in biological signaling systems. Science (New York, N.Y.). 284: 92-6. PMID 10102825 DOI: 10.1126/science.284.5411.92  1
1999 Buck E, Li J, Chen Y, Weng G, Scarlata S, Iyengar R. Resolution of a signal transfer region from a general binding domain in gbeta for stimulation of phospholipase C-beta2. Science (New York, N.Y.). 283: 1332-5. PMID 10037604 DOI: 10.1126/Science.283.5406.1332  0.68
1999 Bhalla US, Iyengar R. Emergent properties of networks of biological signaling pathways. Science (New York, N.Y.). 283: 381-7. PMID 9888852 DOI: 10.1126/science.283.5400.381  1
1998 Jordan JD, Iyengar R. Modes of interactions between signaling pathways. Biochemical Pharmacology. 55: 1347-52. PMID 10076524 DOI: 10.1016/S0006-2952(97)00620-5  1
1998 Smit MJ, Verzijl D, Iyengar R. Identity of adenylyl cyclase isoform determines the rate of cell cycle progression in NIH 3T3 cells. Proceedings of the National Academy of Sciences of the United States of America. 95: 15084-9. PMID 9844019 DOI: 10.1073/Pnas.95.25.15084  1
1998 Blitzer RD, Connor JH, Brown GP, Wong T, Shenolikar S, Iyengar R, Landau EM. Gating of CaMKII by cAMP-regulated protein phosphatase activity during LTP. Science (New York, N.Y.). 280: 1940-2. PMID 9632393 DOI: 10.1126/Science.280.5371.1940  1
1998 Ford CE, Skiba NP, Bae H, Daaka Y, Reuveny E, Shekter LR, Rosal R, Weng G, Yang CS, Iyengar R, Miller RJ, Jan LY, Lefkowitz RJ, Hamm HE. Molecular basis for interactions of G protein betagamma subunits with effectors. Science (New York, N.Y.). 280: 1271-4. PMID 9596582 DOI: 10.1126/Science.280.5367.1271  1
1998 Chen J, Bander JA, Santore TA, Chen Y, Ram PT, Smit MJ, Iyengar R. Expression of Q227L-galphas in MCF-7 human breast cancer cells inhibits tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 95: 2648-52. PMID 9482941 DOI: 10.1073/Pnas.95.5.2648  1
1998 Smit MJ, Iyengar R. Mammalian adenylyl cyclases. Advances in Second Messenger and Phosphoprotein Research. 32: 1-21. PMID 9421583 DOI: 10.1016/S1040-7952(98)80003-7  1
1997 Chen Y, Harry A, Li J, Smit MJ, Bai X, Magnusson R, Pieroni JP, Weng G, Iyengar R. Adenylyl cyclase 6 is selectively regulated by protein kinase A phosphorylation in a region involved in Galphas stimulation. Proceedings of the National Academy of Sciences of the United States of America. 94: 14100-4. PMID 9391159 DOI: 10.1073/Pnas.94.25.14100  1
1997 Harry A, Chen Y, Magnusson R, Iyengar R, Weng G. Differential regulation of adenylyl cyclases by Galphas. The Journal of Biological Chemistry. 272: 19017-21. PMID 9228084 DOI: 10.1074/jbc.272.30.19017  0.68
1997 Chen Y, Weng G, Li J, Harry A, Pieroni J, Dingus J, Hildebrandt JD, Guarnieri F, Weinstein H, Iyengar R. A surface on the G protein beta-subunit involved in interactions with adenylyl cyclases. Proceedings of the National Academy of Sciences of the United States of America. 94: 2711-4. PMID 9122261 DOI: 10.1073/Pnas.94.6.2711  1
1997 Johnson RA, Désaubry L, Bianchi G, Shoshani I, Lyons E, Taussig R, Watson PA, Cali JJ, Krupinski J, Pieroni JP, Iyengar R. Isozyme-dependent sensitivity of adenylyl cyclases to P-site-mediated inhibition by adenine nucleosides and nucleoside 3'-polyphosphates. The Journal of Biological Chemistry. 272: 8962-6. PMID 9083018 DOI: 10.1074/Jbc.272.14.8962  1
1997 Iyengar R. There are GAPS and there are GAPS. Science (New York, N.Y.). 275: 42-3. PMID 8999536 DOI: 10.1126/science.275.5296.42  1
1996 Weng G, Li J, Dingus J, Hildebrandt JD, Weinstein H, Iyengar R. Gbeta subunit interacts with a peptide encoding region 956-982 of adenylyl cyclase 2. Cross-linking of the peptide to free Gbetagamma but not the heterotrimer. The Journal of Biological Chemistry. 271: 26445-8. PMID 8900107 DOI: 10.1074/Jbc.271.43.26445  0.72
1996 Iyengar R. Gating by cyclic AMP: expanded role for an old signaling pathway. Science (New York, N.Y.). 271: 461-3. PMID 8560257 DOI: 10.1126/science.271.5248.461  1
1995 Blitzer RD, Wong T, Nouranifar R, Iyengar R, Landau EM. Postsynaptic cAMP pathway gates early LTP in hippocampal CA1 region. Neuron. 15: 1403-14. PMID 8845163 DOI: 10.1016/0896-6273(95)90018-7  1
1995 Chen J, Iyengar R. Interactions between the Gs/protein kinase A and the Ras/MAP-kinase signalling pathways. Biochemical Society Transactions. 23: 129-33. PMID 7758691  1
1995 Pieroni JP, Harry A, Chen J, Jacobowitz O, Magnusson RP, Iyengar R. Distinct characteristics of the basal activities of adenylyl cyclases 2 and 6. The Journal of Biological Chemistry. 270: 21368-73. PMID 7673172 DOI: 10.1074/jbc.270.36.21368  1
1995 Mons N, Harry A, Dubourg P, Premont RT, Iyengar R, Cooper DM. Immunohistochemical localization of adenylyl cyclase in rat brain indicates a highly selective concentration at synapses. Proceedings of the National Academy of Sciences of the United States of America. 92: 8473-7. PMID 7667314  0.88
1994 Chen J, Iyengar R. Suppression of Ras-induced transformation of NIH 3T3 cells by activated G alpha s. Science (New York, N.Y.). 263: 1278-81. PMID 8122111 DOI: 10.1126/Science.8122111  1
1994 De Vivo M, Iyengar R. Activated Gq-alpha potentiates platelet-derived growth factor-stimulated mitogenesis in confluent cell cultures. The Journal of Biological Chemistry. 269: 19671-4. PMID 8051041  1
1994 Jacobowitz O, Iyengar R. Phorbol ester-induced stimulation and phosphorylation of adenylyl cyclase 2. Proceedings of the National Academy of Sciences of the United States of America. 91: 10630-4. PMID 7938004 DOI: 10.1073/pnas.91.22.10630  1
1994 Chen J, Carty DJ, Iyengar R. Adenylyl cyclase assay for beta gamma subunits of G proteins. Methods in Enzymology. 237: 451-6. PMID 7935019 DOI: 10.1016/S0076-6879(94)37082-6  0.8
1994 Carty DJ, Iyengar R. Guanosine 5'-(gamma-thio)triphosphate binding assay for solubilized G proteins. Methods in Enzymology. 237: 38-44. PMID 7935012 DOI: 10.1016/S0076-6879(94)37051-6  1
1994 Ma HW, Iyengar R, Premont RT. Amplification of phosphatidylinositol-specific phospholipase C-beta isoforms using degenerate primers. Methods in Enzymology. 238: 244-52. PMID 7799790 DOI: 10.1016/0076-6879(94)38022-8  0.88
1994 Jacobowitz O, Chen J, Iyengar R. Transient expression assays for mammalian adenylyl cyclases. Methods in Enzymology. 238: 108-16. PMID 7799778 DOI: 10.1016/0076-6879(94)38010-4  0.72
1993 Jacobowitz O, Chen J, Premont RT, Iyengar R. Stimulation of specific types of Gs-stimulated adenylyl cyclases by phorbol ester treatment. The Journal of Biological Chemistry. 268: 3829-32. PMID 8440678  0.88
1993 Iyengar R. Multiple families of Gs-regulated adenylyl cyclases. Advances in Second Messenger and Phosphoprotein Research. 28: 27-36. PMID 8398413  1
1993 Ma HW, Blitzer RD, Healy EC, Premont RT, Landau EM, Iyengar R. Receptor-evoked Cl- current in Xenopus oocytes is mediated through a beta-type phospholipase C. Cloning of a new form of the enzyme. The Journal of Biological Chemistry. 268: 19915-8. PMID 8397190  1
1993 Chen J, Iyengar R. Inhibition of cloned adenylyl cyclases by mutant-activated Gi-alpha and specific suppression of type 2 adenylyl cyclase inhibition by phorbol ester treatment. The Journal of Biological Chemistry. 268: 12253-6. PMID 8389756  1
1993 Pieroni JP, Jacobowitz O, Chen J, Iyengar R. Signal recognition and integration by Gs-stimulated adenylyl cyclases. Current Opinion in Neurobiology. 3: 345-51. PMID 8369627 DOI: 10.1016/0959-4388(93)90127-K  0.32
1993 Iyengar R. Molecular and functional diversity of mammalian Gs-stimulated adenylyl cyclases. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 7: 768-75. PMID 8330684 DOI: 10.1096/Fasebj.7.9.8330684  1
1992 De Vivo M, Chen J, Codina J, Iyengar R. Enhanced phospholipase C stimulation and transformation in NIH-3T3 cells expressing Q209LGq-alpha-subunits. The Journal of Biological Chemistry. 267: 18263-6. PMID 1526966  1
1992 Kroll SD, Chen J, De Vivo M, Carty DJ, Buku A, Premont RT, Iyengar R. The Q205LGo-alpha subunit expressed in NIH-3T3 cells induces transformation. The Journal of Biological Chemistry. 267: 23183-8. PMID 1429665  1
1992 Premont RT, Chen J, Ma HW, Ponnapalli M, Iyengar R. Two members of a widely expressed subfamily of hormone-stimulated adenylyl cyclases. Proceedings of the National Academy of Sciences of the United States of America. 89: 9809-13. PMID 1409703 DOI: 10.1073/Pnas.89.20.9809  0.88
1992 Premont RT, Jacobowitz O, Iyengar R. Lowered responsiveness of the catalyst of adenylyl cyclase to stimulation by GS in heterologous desensitization: a role for adenosine 3',5'-monophosphate-dependent phosphorylation. Endocrinology. 131: 2774-84. PMID 1332848 DOI: 10.1210/endo.131.6.1332848  0.88
1991 Carty DJ, Premont RT, Iyengar R. Quantitative immunoblotting of G-protein subunits. Methods in Enzymology. 195: 302-15. PMID 1903493 DOI: 10.1016/0076-6879(91)95175-J  0.88
1991 Codina J, Carty DJ, Birnbaumer L, Iyengar R. Purification of G proteins. Methods in Enzymology. 195: 177-88. PMID 1851927 DOI: 10.1016/0076-6879(91)95164-F  1
1991 Padrell E, Carty DJ, Moriarty TM, Hildebrandt JD, Landau EM, Iyengar R. Two forms of the bovine brain Go that stimulate the inositol trisphosphate-mediated Cl- currents in Xenopus oocytes. Distinct guanine nucleotide binding properties. The Journal of Biological Chemistry. 266: 9771-7. PMID 1851756  1
1991 Kroll SD, Omri G, Landau EM, Iyengar R. Activated alpha subunit of Go protein induces oocyte maturation. Proceedings of the National Academy of Sciences of the United States of America. 88: 5182-6. PMID 1828893 DOI: 10.1073/pnas.88.12.5182  1
1990 Senogles SE, Spiegel AM, Padrell E, Iyengar R, Caron MG. Specificity of receptor-G protein interactions. Discrimination of Gi subtypes by the D2 dopamine receptor in a reconstituted system. The Journal of Biological Chemistry. 265: 4507-14. PMID 2137824  1
1990 Iyengar R, Birnbaumer L. Roles of G proteins and G protein subunits in signal transduction. Lymphokine Research. 9: 533-7. PMID 2128642  1
1990 Carty DJ, Padrell E, Codina J, Birnbaumer L, Hildebrandt JD, Iyengar R. Distinct guanine nucleotide binding and release properties of the three Gi proteins. The Journal of Biological Chemistry. 265: 6268-73. PMID 2108158  1
1990 Carty DJ, Iyengar R. A 43 kDa form of the GTP-binding protein Gi3 in human erythrocytes. Febs Letters. 262: 101-3. PMID 2108051 DOI: 10.1016/0014-5793(90)80163-D  1
1990 Moriarty TM, Padrell E, Carty DJ, Omri G, Landau EM, Iyengar R. Go protein as signal transducer in the pertussis toxin-sensitive phosphatidylinositol pathway. Nature. 343: 79-82. PMID 2104959 DOI: 10.1038/343079a0  1
1989 Rich KA, Iyengar R. Desensitization of the beta-adrenergic receptor of the S49 murine lymphoma cell: mechanism of receptor loss and recovery. Journal of Molecular Endocrinology. 3: 219-27. PMID 2556154  1
1989 Premont RT, Buku A, Iyengar R. The G alpha z gene product in human erythrocytes. Identification as a 41-kilodalton protein. The Journal of Biological Chemistry. 264: 14960-4. PMID 2504714  0.88
1989 Premont RT, Iyengar R. Heterologous desensitization of the liver adenylyl cyclase: analysis of the role of G-proteins. Endocrinology. 125: 1151-60. PMID 2503363 DOI: 10.1210/endo-125-3-1151  1
1989 Moriarty TM, Sealfon SC, Carty DJ, Roberts JL, Iyengar R, Landau EM. Coupling of exogenous receptors to phospholipase C in Xenopus oocytes through pertussis toxin-sensitive and -insensitive pathways. Cross-talk through heterotrimeric G-proteins. The Journal of Biological Chemistry. 264: 13524-30. PMID 2474532  1
1988 Yatani A, Mattera R, Codina J, Graf R, Okabe K, Padrell E, Iyengar R, Brown AM, Birnbaumer L. The G protein-gated atrial K+ channel is stimulated by three distinct Gi alpha-subunits. Nature. 336: 680-2. PMID 3143915 DOI: 10.1038/336680a0  1
1988 Premont RT, Iyengar R. Glucagon-induced desensitization of adenylyl cyclase in primary cultures of chick hepatocytes. Evidence for multiple pathways. The Journal of Biological Chemistry. 263: 16087-95. PMID 2846535  1
1988 Iyengar R, Rich KA, Herberg JT, Premont RT, Codina J. Glucagon receptor-mediated activation of Gs is accompanied by subunit dissociation. The Journal of Biological Chemistry. 263: 15348-53. PMID 2844810  1
1988 Iyengar R, Herberg JT, Rich KA. The glucagon receptor: structural analysis by covalent labeling techniques. Pharmacology & Therapeutics. 37: 151-65. PMID 2837791 DOI: 10.1016/0163-7258(88)90023-X  1
1988 Moriarty TM, Gillo B, Carty DJ, Premont RT, Landau EM, Iyengar R. Beta gamma subunits of GTP-binding proteins inhibit muscarinic receptor stimulation of phospholipase C. Proceedings of the National Academy of Sciences of the United States of America. 85: 8865-9. PMID 2461557  1
1987 Iyengar R, Rich KA, Herberg JT, Grenet D, Mumby S, Codina J. Identification of a new GTP-binding protein. A Mr = 43,000 substrate for pertussis toxin. The Journal of Biological Chemistry. 262: 9239-45. PMID 3110156  1
1987 Padrell E, Herberg JT, Monsatirsky B, Floyd G, Premont RT, Iyengar R. The hepatic glucagon receptor: a comparative study of the regulatory and structural properties. Endocrinology. 120: 2316-25. PMID 3032585 DOI: 10.1210/endo-120-6-2316  1
1985 Hildebrandt JD, Codina J, Rosenthal W, Sunyer T, Iyengar R, Birnbaumer L. Properties of human erythrocyte Ns and Ni, the regulatory components of adenylate cyclase, as purified without regulatory ligands. Advances in Cyclic Nucleotide and Protein Phosphorylation Research. 19: 87-101. PMID 3159187  1
1985 Birnbaumer L, Codina J, Mattera R, Cerione RA, Hildebrandt JD, Sunyer T, Rojas FJ, Caron MG, Lefkowitz RJ, Iyengar R. Regulation of hormone receptors and adenylyl cyclases by guanine nucleotide binding N proteins. Recent Progress in Hormone Research. 41: 41-99. PMID 2996090 DOI: 10.1016/B978-0-12-571141-8.50006-8  1
1985 Herberg JT, Iyengar R. Covalent labeling of the hepatic glucagon receptor. Methods in Enzymology. 109: 207-15. PMID 2985915 DOI: 10.1016/0076-6879(85)09087-5  1
1985 Iyengar R, Herberg JT. Wheat germ lectin-sepharose affinity adsorption assay for the soluble glucagon receptor. Methods in Enzymology. 109: 13-20. PMID 2985914 DOI: 10.1016/0076-6879(85)09072-3  1
1984 Rich KA, Codina J, Floyd G, Sekura R, Hildebrandt JD, Iyengar R. Glucagon-induced heterologous desensitization of the MDCK cell adenylyl cyclase. Increases in the apparent levels of the inhibitory regulator (Ni). The Journal of Biological Chemistry. 259: 7893-901. PMID 6539777  1
1984 Codina J, Hildebrandt JD, Sekura RD, Birnbaumer M, Bryan J, Manclark CR, Iyengar R, Birnbaumer L. Ns and Ni, the stimulatory and inhibitory regulatory components of adenylyl cyclases. Purification of the human erythrocyte proteins without the use of activating regulatory ligands. The Journal of Biological Chemistry. 259: 5871-86. PMID 6325453  1
1984 Iyengar R, Herberg JT. Structural analysis of the hepatic glucagon receptor. Identification of a guanine nucleotide-sensitive hormone-binding region. The Journal of Biological Chemistry. 259: 5222-9. PMID 6325424  1
1984 Codina J, Hildebrandt J, Sunyer T, Sekura RD, Manclark CR, Iyengar R, Birnbaumer L. Mechanisms in the vectorial receptor-adenylate cyclase signal transduction. Advances in Cyclic Nucleotide and Protein Phosphorylation Research. 17: 111-25. PMID 6145316  1
1984 Iyengar R, Herberg JT, Rich KA. Characterization of the hepatic glucagon receptor. Journal of Receptor Research. 4: 247-65. PMID 6098655 DOI: 10.3109/10799898409042553  1
1984 Herberg JT, Codina J, Rich KA, Rojas FJ, Iyengar R. The hepatic glucagon receptor. Solubilization, characterization, and development of an affinity adsorption assay for the soluble receptor. The Journal of Biological Chemistry. 259: 9285-94. PMID 6086631  1
1983 Kirchick HJ, Iyengar R, Birnbaumer L. Human chorionic gonadotropin-induced heterologous desensitization of adenylyl cyclase from highly luteinized rat ovaries: attenuation of regulatory N component activity. Endocrinology. 113: 1638-46. PMID 6313327 DOI: 10.1210/endo-113-5-1638  1
1983 Codina J, Hildebrandt J, Iyengar R, Birnbaumer L, Sekura RD, Manclark CR. Pertussis toxin substrate, the putative Ni component of adenylyl cyclases, is an alpha beta heterodimer regulated by guanine nucleotide and magnesium. Proceedings of the National Academy of Sciences of the United States of America. 80: 4276-80. PMID 6308612 DOI: 10.1073/PNAS.80.14.4276  1
1983 Rojas FJ, Swartz TL, Iyengar R, Garber AJ, Birnbaumer L. Monoiodoglucagon: synthesis, purification by high pressure liquid chromatography, and characteristics as a receptor probe. Endocrinology. 113: 711-9. PMID 6307649 DOI: 10.1210/endo-113-2-711  1
1983 Briggs MM, Stadel JM, Iyengar R, Lefkowitz RJ. Functional modification of the guanine nucleotide regulatory protein after desensitization of turkey erythrocytes by catecholamines. Archives of Biochemistry and Biophysics. 224: 142-51. PMID 6307146 DOI: 10.1016/0003-9861(83)90198-4  1
1983 Hildebrandt JD, Sekura RD, Codina J, Iyengar R, Manclark CR, Birnbaumer L. Stimulation and inhibition of adenylyl cyclases mediated by distinct regulatory proteins. Nature. 302: 706-9. PMID 6300694 DOI: 10.1038/302706A0  1
1982 Somkuti SG, Hildebrandt JD, Herberg JT, Iyengar R. Divalent cation regulation of adenylyl cyclase. An allosteric site on the catalytic component. The Journal of Biological Chemistry. 257: 6387-93. PMID 6804466  1
1982 Iyengar R, Birnbaumer L. Hormone receptor modulates the regulatory component of adenylyl cyclase by reducing its requirement for Mg2+ and enhancing its extent of activation by guanine nucleotides. Proceedings of the National Academy of Sciences of the United States of America. 79: 5179-83. PMID 6291028 DOI: 10.1073/PNAS.79.17.5179  1
1982 Abramowitz J, Iyengar R, Birnbaumer L. Guanine nucleotide and magnesium ion regulation of the interaction of gonadotropic and beta-adrenergic receptors with their hormones: a comparative study using a single membrane system. Endocrinology. 110: 336-46. PMID 6276131 DOI: 10.1210/endo-110-2-336  1
1981 Iyengar R. Hysteretic activation of adenylyl cyclases. II. Mg ion regulation of the activation of the regulatory component as analyzed by reconstitution. The Journal of Biological Chemistry. 256: 11042-50. PMID 7287750  1
1981 Iyengar R, Birnbaumer L. Hysteretic activation of adenylyl cyclases. I. Effect of Mg ion on the rate of activation by guanine nucleotides and fluoride. The Journal of Biological Chemistry. 256: 11036-41. PMID 7287749  1
1981 Iyengar R, Birnbaumer L. Agonist-specific desensitization: molecular locus and possible mechanism. Advances in Cyclic Nucleotide Research. 14: 93-100. PMID 6269407  1
1981 Iyengar R, Bhat MK, Riser ME, Birnbaumer L. Receptor-specific desensitization of the S49 lymphoma cell adenylyl cyclase. Unaltered behavior of the regulatory component. The Journal of Biological Chemistry. 256: 4810-5. PMID 6262304  1
1980 Abramowitz J, Iyengar R, Birnbaumer L. On the mode of action of catecholamines on the turkey erythrocyte adenylyl cyclase. Evaluation of basic activity states after removal of endogenous GDP and interpretation of nucleotide regulation and hormone activation in terms of a two-state model. The Journal of Biological Chemistry. 255: 8259-65. PMID 7410362  1
1980 Birnbaumer L, Swartz TL, Abramowitz J, Mintz PW, Iyengar R. Transient and steady state kinetics of the interaction of guanyl nucleotides with the adenylyl cyclase system from rat liver plasma membranes. Interpretation in terms of a simple two-state model. The Journal of Biological Chemistry. 255: 3542-51. PMID 7364755  1
1980 Bhat MK, Iyengar R, Abramowitz J, Bordelon-Riser ME, Birnbaumer L. Naturally soluble component(s) that confer(s) guanine nucleotide and fluoride sensitivity to adenylate cyclase. Proceedings of the National Academy of Sciences of the United States of America. 77: 3836-40. PMID 6933440 DOI: 10.1073/Pnas.77.7.3836  1
1980 Iyengar R, Mintz PW, Swartz TL, Birnbaumer L. Divalent cation-induced desensitization of glucagon-stimulable adenylyl cyclase in rat liver plasma membrane. GTP-dependent stimulation by glucagon. The Journal of Biological Chemistry. 255: 11875-82. PMID 6777386  1
1980 Iyengar R, Abramowitz J, Bordelon-Riser M, Blume AJ, Birnbaumer L. Regulation of hormone-receptor coupling to adenylyl cyclase. Effects of GTP and GDP. The Journal of Biological Chemistry. 255: 10312-21. PMID 6253469  1
1980 Iyengar R, Abramowitz J, Bordelon-Riser M, Birnbaumer L. Hormone receptor-mediated stimulation of adenylyl cyclase systems. Nucleotide effects and analysis in terms of a simple two-state model for the basic receptor-affected enzyme. The Journal of Biological Chemistry. 255: 3558-64. PMID 6245083  1
1980 Birnbaumer L, Bearer CF, Iyengar R. A two-state model of an enzyme with an allosteric regulatory site capable of metabolizing the regulatory ligand. Simplified mathematical treatments of transient and steady state kinetics of an activator and its competitive inhibition as applied to adenylyl cyclases. The Journal of Biological Chemistry. 255: 3552-7. PMID 6102566  1
1979 Abramowitz J, Iyengar R, Birnbaumer L. Guanyl nucleotide regulation of hormonally-responsive adenylyl cyclases. Molecular and Cellular Endocrinology. 16: 129-46. PMID 230102 DOI: 10.1016/0303-7207(79)90022-4  1
1979 Iyengar R, Birnbaumer L. Coupling of the glucagon receptor to adenylyl cyclase by GDP: evidence for two levels of regulation of adenylyl cyclase. Proceedings of the National Academy of Sciences of the United States of America. 76: 3189-93. PMID 226958 DOI: 10.1073/PNAS.76.7.3189  1
1979 Iyengar R, Swartz TL, Birnbaumer L. Coupling of glucagon receptor to adenylyl cyclase. Requirement of a receptor-related guanyl nucleotide binding site for coupling of receptor to the enzyme. The Journal of Biological Chemistry. 254: 1119-23. PMID 216687  1
1976 Iyengar R, Lepper KG, Mailman DS. Involvement of microtubules and microfilaments in the action of vasopressing in canine renal medulla. Journal of Supramolecular Structure. 5: 521(373)-530(382). PMID 195139 DOI: 10.1002/jss.400050409  0.01
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