Michael E. Hildebrand, Ph.D. - Publications

Affiliations: 
University of Toronto, Toronto, ON, Canada 
Area:
ion channels, pain

22/37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Yadav A, Matson KJE, Li L, Hua I, Petrescu J, Kang K, Alkaslasi MR, Lee DI, Hasan S, Galuta A, Dedek A, Ameri S, Parnell J, Alshardan MM, Qumqumji FA, ... ... Hildebrand ME, et al. A cellular taxonomy of the adult human spinal cord. Neuron. 111: 328-344.e7. PMID 36731429 DOI: 10.1016/j.neuron.2023.01.007  0.558
2023 Correa BHM, Moreira CR, Hildebrand ME, Vieira LB. The Role of Voltage-Gated Calcium Channels in Basal Ganglia Neurodegenerative Disorders. Current Neuropharmacology. 21: 183-201. PMID 35339179 DOI: 10.2174/1570159X20666220327211156  0.305
2021 McNeill J, Rudyk C, Hildebrand ME, Salmaso N. Ion Channels and Electrophysiological Properties of Astrocytes: Implications for Emergent Stimulation Technologies. Frontiers in Cellular Neuroscience. 15: 644126. PMID 34093129 DOI: 10.3389/fncel.2021.644126  0.39
2021 Harding EK, Dedek A, Bonin RP, Salter MW, Snutch TP, Hildebrand ME. The T-type calcium channel antagonist, Z944, reduces spinal excitability and pain hypersensitivity. British Journal of Pharmacology. PMID 33871884 DOI: 10.1111/bph.15498  0.737
2020 Mahmoud H, Martin N, Hildebrand ME. Conserved contributions of NMDA receptor subtypes to synaptic responses in lamina II spinal neurons across early postnatal development. Molecular Brain. 13: 31. PMID 32138769 DOI: 10.1186/S13041-020-00566-9  0.351
2019 Dedek A, Xu J, Kandegedara CM, Lorenzo LÉ, Godin AG, De Koninck Y, Lombroso PJ, Tsai EC, Hildebrand ME. Loss of STEP61 couples disinhibition to N-methyl-d-aspartate receptor potentiation in rodent and human spinal pain processing. Brain : a Journal of Neurology. 142: 1535-1546. PMID 31135041 DOI: 10.1093/Brain/Awz105  0.391
2016 Hildebrand ME, Xu J, Dedek A, Li Y, Sengar AS, Beggs S, Lombroso PJ, Salter MW. Potentiation of Synaptic GluN2B NMDAR Currents by Fyn Kinase Is Gated through BDNF-Mediated Disinhibition in Spinal Pain Processing. Cell Reports. 17: 2753-2765. PMID 27926876 DOI: 10.1016/J.Celrep.2016.11.024  0.748
2015 Hildebrand ME, Snutch TP. The unusual suspects: Regulation of retinal calcium channels by somatostatin. Channels (Austin, Tex.). 9: 61-2. PMID 25715059 DOI: 10.1080/19336950.2015.1018000  0.688
2014 Hildebrand ME, Pitcher GM, Harding EK, Li H, Beggs S, Salter MW. GluN2B and GluN2D NMDARs dominate synaptic responses in the adult spinal cord. Scientific Reports. 4: 4094. PMID 24522697 DOI: 10.1038/Srep04094  0.717
2014 Bourinet E, Altier C, Hildebrand ME, Trang T, Salter MW, Zamponi GW. Calcium-permeable ion channels in pain signaling. Physiological Reviews. 94: 81-140. PMID 24382884 DOI: 10.1152/Physrev.00023.2013  0.783
2012 Isope P, Hildebrand ME, Snutch TP. Contributions of T-type voltage-gated calcium channels to postsynaptic calcium signaling within Purkinje neurons. Cerebellum (London, England). 11: 651-65. PMID 20734177 DOI: 10.1007/S12311-010-0195-4  0.81
2011 Hildebrand ME, Mezeyova J, Smith PL, Salter MW, Tringham E, Snutch TP. Identification of sodium channel isoforms that mediate action potential firing in lamina I/II spinal cord neurons. Molecular Pain. 7: 67. PMID 21910862 DOI: 10.1186/1744-8069-7-67  0.765
2011 Hildebrand ME, Smith PL, Bladen C, Eduljee C, Xie JY, Chen L, Fee-Maki M, Doering CJ, Mezeyova J, Zhu Y, Belardetti F, Pajouhesh H, Parker D, Arneric SP, Parmar M, et al. A novel slow-inactivation-specific ion channel modulator attenuates neuropathic pain. Pain. 152: 833-43. PMID 21349638 DOI: 10.1016/J.Pain.2010.12.035  0.787
2010 Singh A, Hildebrand ME, Garcia E, Snutch TP. The transient receptor potential channel antagonist SKF96365 is a potent blocker of low-voltage-activated T-type calcium channels. British Journal of Pharmacology. 160: 1464-75. PMID 20590636 DOI: 10.1111/J.1476-5381.2010.00786.X  0.736
2009 Hildebrand ME, Isope P, Miyazaki T, Nakaya T, Garcia E, Feltz A, Schneider T, Hescheler J, Kano M, Sakimura K, Watanabe M, Dieudonné S, Snutch TP. Functional coupling between mGluR1 and Cav3.1 T-type calcium channels contributes to parallel fiber-induced fast calcium signaling within Purkinje cell dendritic spines. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 9668-82. PMID 19657020 DOI: 10.1523/Jneurosci.0362-09.2009  0.793
2008 Tao J, Hildebrand ME, Liao P, Liang MC, Tan G, Li S, Snutch TP, Soong TW. Activation of corticotropin-releasing factor receptor 1 selectively inhibits CaV3.2 T-type calcium channels. Molecular Pharmacology. 73: 1596-609. PMID 18292205 DOI: 10.1124/Mol.107.043612  0.765
2007 Hildebrand ME, David LS, Hamid J, Mulatz K, Garcia E, Zamponi GW, Snutch TP. Selective inhibition of Cav3.3 T-type calcium channels by Galphaq/11-coupled muscarinic acetylcholine receptors. The Journal of Biological Chemistry. 282: 21043-55. PMID 17535809 DOI: 10.1074/Jbc.M611809200  0.752
2006 Hildebrand ME, Snutch TP. Contributions of T-type calcium channels to the pathophysiology of pain signaling Drug Discovery Today: Disease Mechanisms. 3: 335-341. DOI: 10.1016/J.Ddmec.2006.10.001  0.748
2005 Vieira LB, Kushmerick C, Hildebrand ME, Garcia E, Stea A, Cordeiro MN, Richardson M, Gomez MV, Snutch TP. Inhibition of high voltage-activated calcium channels by spider toxin PnTx3-6. The Journal of Pharmacology and Experimental Therapeutics. 314: 1370-7. PMID 15933156 DOI: 10.1124/Jpet.105.087023  0.78
2004 Spacey SD, Hildebrand ME, Materek LA, Bird TD, Snutch TP. Functional implications of a novel EA2 mutation in the P/Q-type calcium channel. Annals of Neurology. 56: 213-20. PMID 15293273 DOI: 10.1002/Ana.20169  0.668
2004 McRory JE, Hamid J, Doering CJ, Garcia E, Parker R, Hamming K, Chen L, Hildebrand M, Beedle AM, Feldcamp L, Zamponi GW, Snutch TP. The CACNA1F gene encodes an L-type calcium channel with unique biophysical properties and tissue distribution. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 1707-18. PMID 14973233 DOI: 10.1523/Jneurosci.4846-03.2004  0.769
2004 Hildebrand ME, McRory JE, Snutch TP, Stea A. Mammalian voltage-gated calcium channels are potently blocked by the pyrethroid insecticide allethrin. The Journal of Pharmacology and Experimental Therapeutics. 308: 805-13. PMID 14634047 DOI: 10.1124/Jpet.103.058792  0.814
Low-probability matches (unlikely to be authored by this person)
2022 Dedek A, Xu J, Lorenzo LÉ, Godin AG, Kandegedara CM, Glavina G, Landrigan JA, Lombroso PJ, De Koninck Y, Tsai EC, Hildebrand ME. Sexual dimorphism in a neuronal mechanism of spinal hyperexcitability across rodent and human models of pathological pain. Brain : a Journal of Neurology. PMID 35323848 DOI: 10.1093/brain/awab408  0.248
2021 Soh MS, Bagnall RD, Bennett MF, Bleakley LE, Mohamed Syazwan ES, Marie Phillips A, Chiam MDF, McKenzie CE, Hildebrand M, Crompton D, Bahlo M, Semsarian C, Scheffer IE, Berkovic SF, Reid CA. Loss-of-function variants in K 11.1 cardiac channels as a biomarker for SUDEP. Annals of Clinical and Translational Neurology. PMID 34002542 DOI: 10.1002/acn3.51381  0.238
2022 Dedek A, Hildebrand ME. Advances and Barriers in Understanding Presynaptic -Methyl--Aspartate Receptors in Spinal Pain Processing. Frontiers in Molecular Neuroscience. 15: 864502. PMID 35431805 DOI: 10.3389/fnmol.2022.864502  0.233
2021 Temi S, Rudyk C, Armstrong J, Landrigan JA, Dedek C, Salmaso N, Hildebrand ME. Differential expression of GluN2 NMDA receptor subunits in the dorsal horn of male and female rats. Channels (Austin, Tex.). 15: 179-192. PMID 33509021 DOI: 10.1080/19336950.2020.1871205  0.224
2004 Kono H, Osako H, Sasaki M, Takahashi T, Ohga Y, Asano T, Hildebrand M, Weinberg NN. Dynamic solvent effects on the fading of a merocyanine formed from a spironaphthoxazine. A case of a strong coupling between chemical and medium coordinate Physical Chemistry Chemical Physics. 6: 2260-2266. DOI: 10.1039/B316983A  0.223
2006 Schermuly RT, Schulz A, Ghofrani HA, Breitenbach CS, Weissmann N, Hildebrand M, Kurz J, Grimminger F, Seeger W. Comparison of pharmacokinetics and vasodilatory effect of nebulized and infused iloprost in experimental pulmonary hypertension: Rapid tolerance development Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung. 19: 353-363. PMID 17034310 DOI: 10.1089/Jam.2006.19.353  0.205
2003 Goto Y, Takahashi T, Ohga Y, Asano T, Hildebrand M, Weinberg N. Dynamic solvent effects on the thermal cyclization of a hexadienone formed from a diphenylnaphthopyran: An example of a system with distinctly separate medium and chemical contributions to the overall reaction coordinate Physical Chemistry Chemical Physics. 5: 1825-1830. DOI: 10.1039/B212673G  0.201
2002 Schermuly RT, Schulz A, Ghofrani HA, Meidow A, Rose F, Roehl A, Weissmann N, Hildebrand M, Kurz J, Grimminger F, Walmrath D, Seeger W. Pharmacokinetics and metabolism of infused versus inhaled iloprost in isolated rabbit lungs Journal of Pharmacology and Experimental Therapeutics. 303: 741-745. PMID 12388660 DOI: 10.1124/Jpet.303.2.741  0.201
2023 Parnell J, Martin N, Dedek A, Rudyk C, Landrigan J, Bellavance J, VanDerLoo S, Tsai EC, Hildebrand ME. Cannabinoid CB1 Receptor Expression and Localization in the Dorsal Horn of Male and Female Rat and Human Spinal Cord. Canadian Journal of Pain = Revue Canadienne De La Douleur. 7: 2264895. PMID 38170158 DOI: 10.1080/24740527.2023.2264895  0.184
2017 Li M, Maljevic S, Phillips AM, Petrovski S, Hildebrand M, Burgess R, Mount T, Zara F, Striano P, Schubert J, Thiele H, Nürnberg P, Wong M, Weisenberg JL, Thio LL, et al. Gain-of-function HCN2 variants in genetic epilepsy. Human Mutation. PMID 29064616 DOI: 10.1002/humu.23357  0.142
2024 Xu Z, Sadleir L, Goel H, Jiao X, Niu Y, Zhou Z, de Valles-Ibáñez G, Poke G, Hildebrand M, Lieffering N, Qin J, Yang Z. Genotype and phenotype correlation of -related neurological disorders. Journal of Medical Genetics. PMID 38272663 DOI: 10.1136/jmg-2023-109638  0.09
2003 Hildebrand M, Cui J, Mihaliuk E, Wang J, Showalter K. Synchronization of spatiotemporal patterns in locally coupled excitable media. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 68: 026205. PMID 14525082 DOI: 10.1103/Physreve.68.026205  0.059
2006 Vetterlein K, Büche K, Hildebrand M, Scriba GK, Lehmann J. Capillary electrophoresis for the characterization of the complex dendrimeric contrast agent Gadomer. Electrophoresis. 27: 2400-12. PMID 16786491 DOI: 10.1002/elps.200600039  0.04
2021 Norlock SM, Okanya PW, Trataris A, Hildebrand ME, Baziki JD, Belkourati I, Ellis M. South-to-south mentoring as a vehicle for implementing sustainable health security in Africa. One Health Outlook. 3: 20. PMID 34610850 DOI: 10.1186/s42522-021-00050-x  0.022
2007 Vetterlein K, Bergmann U, Büche K, Walker M, Lehmann J, Linscheid MW, Scriba GK, Hildebrand M. Comprehensive profiling of the complex dendrimeric contrast agent Gadomer using a combined approach of CE, MS, and CE-MS. Electrophoresis. 28: 3088-99. PMID 17674421 DOI: 10.1002/elps.200700075  0.02
Hide low-probability matches.