Wilson S. Colucci - Publications

Affiliations: 
Molecular Medicine Boston University, Boston, MA, United States 
Area:
Biochemistry

189 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Croteau D, Qin F, Chambers JM, Kallick E, Luptak I, Panagia M, Pimentel DR, Siwik DA, Colucci WS. Differential Effects of Sacubitril/Valsartan on Diastolic Function in Mice With Obesity-Related Metabolic Heart Disease. Jacc. Basic to Translational Science. 5: 916-927. PMID 33015414 DOI: 10.1016/J.Jacbts.2020.07.006  0.381
2020 Panagia M, He H, Baka T, Pimentel DR, Croteau D, Bachschmid MM, Balschi JA, Colucci WS, Luptak I. Increasing mitochondrial ATP synthesis with butyrate normalizes ADP and contractile function in metabolic heart disease. Nmr in Biomedicine. e4258. PMID 32066202 DOI: 10.1002/nbm.4258  0.322
2019 Tian R, Colucci WS, Arany Z, Bachschmid MM, Ballinger SW, Boudina S, Bruce JE, Busija DW, Dikalov S, Dorn GW, Galis ZS, Gottlieb RA, Kelly DP, Kitsis RN, Kohr MJ, et al. Unlocking the Secrets of Mitochondria in the Cardiovascular System: Path to a Cure in Heart Failure—A Report from the 2018 National Heart, Lung, and Blood Institute Workshop Circulation. 140: 1205-1216. PMID 31769940 DOI: 10.1161/Circulationaha.119.040551  0.314
2019 Luptak I, Qin F, Sverdlov A, Pimentel D, Panagia M, Croteau D, Siwik DA, Bachschmid MM, He H, Balschi JA, Colucci WS. Energetic dysfunction is mediated by mitochondrial ROS and precedes structural remodeling in metabolic heart disease. Antioxidants & Redox Signaling. PMID 31088291 DOI: 10.1089/ars.2018.7707  0.333
2018 Luptak I, Sverdlov AL, Panagia M, Qin F, Pimentel DR, Croteau D, Siwik DA, Ingwall JS, Bachschmid MM, Balschi JA, Colucci WS. Decreased ATP production and myocardial contractile reserve in metabolic heart disease. Journal of Molecular and Cellular Cardiology. PMID 29409987 DOI: 10.1016/J.Yjmcc.2018.01.017  0.32
2018 Qin F, Biolo A, Gao C, Tian J, Kim J, Goodman J, Matsui R, Siwik D, Pimentel D, Cohen R, Colucci W. Glutaredoxin 1 overexpression inhibits JNK activity and ameliorates myocyte apoptosis and progression to heart failure in Galphaq overexpressing transgenic mice Free Radical Biology and Medicine. 128: S38. DOI: 10.1016/J.Freeradbiomed.2018.10.052  0.403
2018 Goodman J, Croteau D, Kirber M, Siwik D, Luptak I, Pimentel D, Colucci W. Sarco-endoplasmic reticulum ATPase participates in the regulation of mitochondrial calcium Free Radical Biology and Medicine. 128: S27. DOI: 10.1016/J.Freeradbiomed.2018.10.020  0.319
2018 Chambers J, Elezaby A, Croteau D, Sverdlov A, Liesa M, Shirihai O, Luptak I, Pimentel D, Siwik D, Colucci W. ABCB10 deletion in cardiomyocytes leads to mitochondrial dysfunction and early death Free Radical Biology and Medicine. 128: S22. DOI: 10.1016/J.Freeradbiomed.2018.10.007  0.407
2017 Swain L, Kiley M, Shao D, Qin F, Colucci W, Bachschmid M. To investigate the Physiological/ Pathophysio-logical Function of Glutaredoxin-1 on the Metabolic Cardiovascular Disease Free Radical Biology and Medicine. 112: 123. DOI: 10.1016/J.Freeradbiomed.2017.10.186  0.42
2016 Brown DA, Perry JB, Allen ME, Sabbah HN, Stauffer BL, Shaikh SR, Cleland JG, Colucci WS, Butler J, Voors AA, Anker SD, Pitt B, Pieske B, Filippatos G, Greene SJ, et al. Expert consensus document: Mitochondrial function as a therapeutic target in heart failure. Nature Reviews. Cardiology. PMID 28004807 DOI: 10.1038/Nrcardio.2016.203  0.432
2016 Gheorghiade M, Larson CJ, Shah SJ, Greene SJ, Cleland JG, Colucci WS, Dunnmon P, Epstein SE, Kim RJ, Parsey RV, Stockbridge N, Carr J, Dinh W, Krahn T, Kramer F, et al. Developing New Treatments for Heart Failure: Focus on the Heart. Circulation. Heart Failure. 9. PMID 27166246 DOI: 10.1161/Circheartfailure.115.002727  0.376
2016 Sverdlov AL, Elezaby A, Qin F, Behring JB, Luptak I, Calamaras TD, Siwik DA, Miller EJ, Liesa M, Shirihai OS, Pimentel DR, Cohen RA, Bachschmid MM, Colucci WS. Mitochondrial Reactive Oxygen Species Mediate Cardiac Structural, Functional, and Mitochondrial Consequences of Diet-Induced Metabolic Heart Disease. Journal of the American Heart Association. 5. PMID 26755553 DOI: 10.1161/Jaha.115.002555  0.757
2016 Qin F, Croteau D, Wang K, Deborah SA, Pimentel DR, Morgan RJ, Cohen RA, Colucci WS. Mutation of the SERCA-Reactive Cysteine-674 to Serine Attenuates Left Ventricular Hypertrophy and Diastolic Dysfunction in Senescent Mice Free Radical Biology and Medicine. 100: S149. DOI: 10.1016/J.Freeradbiomed.2016.10.391  0.38
2015 Miller EJ, Calamaras T, Elezaby A, Sverdlov A, Qin F, Luptak I, Wang K, Sun X, Vijay A, Croteau D, Bachschmid M, Cohen RA, Walsh K, Colucci WS. Partial Liver Kinase B1 (LKB1) Deficiency Promotes Diastolic Dysfunction, De Novo Systolic Dysfunction, Apoptosis, and Mitochondrial Dysfunction With Dietary Metabolic Challenge. Journal of the American Heart Association. 5. PMID 26722122 DOI: 10.1161/Jaha.115.002277  0.784
2015 Yao C, Behring JB, Shao D, Sverdlov AL, Whelan SA, Elezaby A, Yin X, Siwik DA, Seta F, Costello CE, Cohen RA, Matsui R, Colucci WS, McComb ME, Bachschmid MM. Overexpression of Catalase Diminishes Oxidative Cysteine Modifications of Cardiac Proteins. Plos One. 10: e0144025. PMID 26642319 DOI: 10.1371/Journal.Pone.0144025  0.302
2015 Gopal DM, Santhanakrishnan R, Wang YC, Ayalon N, Donohue C, Rahban Y, Perez AJ, Downing J, Liang CS, Gokce N, Colucci WS, Ho JE. Impaired right ventricular hemodynamics indicate preclinical pulmonary hypertension in patients with metabolic syndrome. Journal of the American Heart Association. 4: e001597. PMID 25758604 DOI: 10.1161/Jaha.114.001597  0.332
2015 Calamaras TD, Lee C, Lan F, Ido Y, Siwik DA, Colucci WS. The lipid peroxidation product 4-hydroxy-trans-2-nonenal causes protein synthesis in cardiac myocytes via activated mTORC1-p70S6K-RPS6 signaling. Free Radical Biology & Medicine. 82: 137-46. PMID 25617592 DOI: 10.1016/J.Freeradbiomed.2015.01.007  0.771
2015 Sverdlov AL, Elezaby A, Behring JB, Bachschmid MM, Luptak I, Tu VH, Siwik DA, Miller EJ, Liesa M, Shirihai OS, Pimentel DR, Cohen RA, Colucci WS. High fat, high sucrose diet causes cardiac mitochondrial dysfunction due in part to oxidative post-translational modification of mitochondrial complex II. Journal of Molecular and Cellular Cardiology. 78: 165-73. PMID 25109264 DOI: 10.1016/J.Yjmcc.2014.07.018  0.407
2014 Qin F, Siwik DA, Pimentel DR, Morgan RJ, Biolo A, Tu VH, Kang YJ, Cohen RA, Colucci WS. Cytosolic H2O2 mediates hypertrophy, apoptosis, and decreased SERCA activity in mice with chronic hemodynamic overload. American Journal of Physiology. Heart and Circulatory Physiology. 306: H1453-63. PMID 24633550 DOI: 10.1152/ajpheart.00084.2014  0.414
2014 Ambrosy AP, Butler J, Ahmed A, Vaduganathan M, van Veldhuisen DJ, Colucci WS, Gheorghiade M. The use of digoxin in patients with worsening chronic heart failure: reconsidering an old drug to reduce hospital admissions. Journal of the American College of Cardiology. 63: 1823-32. PMID 24613328 DOI: 10.1016/J.Jacc.2014.01.051  0.42
2014 Behring JB, Kumar V, Whelan SA, Chauhan P, Siwik DA, Costello CE, Colucci WS, Cohen RA, McComb ME, Bachschmid MM. Does reversible cysteine oxidation link the Western diet to cardiac dysfunction? Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 1975-87. PMID 24469991 DOI: 10.1096/Fj.13-233445  0.405
2013 Packer M, Colucci W, Fisher L, Massie BM, Teerlink JR, Young J, Padley RJ, Thakkar R, Delgado-Herrera L, Salon J, Garratt C, Huang B, Sarapohja T. Effect of levosimendan on the short-term clinical course of patients with acutely decompensated heart failure. Jacc. Heart Failure. 1: 103-11. PMID 24621834 DOI: 10.1016/J.Jchf.2012.12.004  0.387
2013 Xanthakis V, Larson MG, Wollert KC, Aragam J, Cheng S, Ho J, Coglianese E, Levy D, Colucci WS, Michael Felker G, Benjamin EJ, Januzzi JL, Wang TJ, Vasan RS. Association of novel biomarkers of cardiovascular stress with left ventricular hypertrophy and dysfunction: implications for screening. Journal of the American Heart Association. 2: e000399. PMID 24200688 DOI: 10.1161/Jaha.113.000399  0.318
2013 Sabbah HN, Tocchetti CG, Wang M, Daya S, Gupta RC, Tunin RS, Mazhari R, Takimoto E, Paolocci N, Cowart D, Colucci WS, Kass DA. Nitroxyl (HNO): A novel approach for the acute treatment of heart failure. Circulation. Heart Failure. 6: 1250-8. PMID 24107588 DOI: 10.1161/Circheartfailure.113.000632  0.422
2013 Qin F, Siwik DA, Lancel S, Zhang J, Kuster GM, Luptak I, Wang L, Tong X, Kang YJ, Cohen RA, Colucci WS. Hydrogen peroxide-mediated SERCA cysteine 674 oxidation contributes to impaired cardiac myocyte relaxation in senescent mouse heart. Journal of the American Heart Association. 2: e000184. PMID 23963753 DOI: 10.1161/Jaha.113.000184  0.55
2012 Calamaras TD, Lee C, Lan F, Ido Y, Siwik DA, Colucci WS. Post-translational modification of serine/threonine kinase LKB1 via Adduction of the Reactive Lipid Species 4-Hydroxy-trans-2-nonenal (HNE) at lysine residue 97 directly inhibits kinase activity. The Journal of Biological Chemistry. 287: 42400-6. PMID 23086944 DOI: 10.1074/Jbc.M112.385831  0.76
2012 Kumar V, Calamaras TD, Haeussler D, Colucci WS, Cohen RA, McComb ME, Pimentel D, Bachschmid MM. Cardiovascular redox and ox stress proteomics. Antioxidants & Redox Signaling. 17: 1528-59. PMID 22607061 DOI: 10.1089/Ars.2012.4706  0.75
2012 Qin F, Siwik DA, Luptak I, Hou X, Wang L, Higuchi A, Weisbrod RM, Ouchi N, Tu VH, Calamaras TD, Miller EJ, Verbeuren TJ, Walsh K, Cohen RA, Colucci WS. The polyphenols resveratrol and S17834 prevent the structural and functional sequelae of diet-induced metabolic heart disease in mice. Circulation. 125: 1757-64, S1-6. PMID 22388319 DOI: 10.1161/Circulationaha.111.067801  0.77
2012 Elezaby A, Miller EJ, Qin F, Liesa M, Shirihai OS, Colucci WS. Cardiac-Specific Fatty Acid Transport Protein 1 (FATP1) Overexpression Causes Decreased Mitochondrial Respiration, Increased Oxidative Stress and Activation of AMPK Free Radical Biology and Medicine. 53: S159. DOI: 10.1016/J.Freeradbiomed.2012.10.434  0.366
2012 Calamaras TD, Lee C, Siwik DA, Colucci WS. The Lipid Peroxidation Product 4-Hydroxy-2-Nonenal (HNE) Causes Cardiac Myocyte Hypertrophy and Activates Hypertrophic MAP Kinase Signaling Free Radical Biology and Medicine. 53: S156. DOI: 10.1016/J.Freeradbiomed.2012.10.426  0.763
2011 Liesa M, Luptak I, Qin F, Hyde BB, Sahin E, Siwik DA, Zhu Z, Pimentel DR, Xu XJ, Ruderman NB, Huffman KD, Doctrow SR, Richey L, Colucci WS, Shirihai OS. Mitochondrial transporter ATP binding cassette mitochondrial erythroid is a novel gene required for cardiac recovery after ischemia/reperfusion. Circulation. 124: 806-13. PMID 21788586 DOI: 10.1161/Circulationaha.110.003418  0.392
2011 Papanicolaou KN, Khairallah RJ, Ngoh GA, Chikando A, Luptak I, O'Shea KM, Riley DD, Lugus JJ, Colucci WS, Lederer WJ, Stanley WC, Walsh K. Mitofusin-2 maintains mitochondrial structure and contributes to stress-induced permeability transition in cardiac myocytes. Molecular and Cellular Biology. 31: 1309-28. PMID 21245373 DOI: 10.1128/Mcb.00911-10  0.36
2011 Kivikko M, Sundberg S, Karlsson MO, Pohjanjousi P, Colucci WS. Acetylation status does not affect levosimendan's hemodynamic effects in heart failure patients. Scandinavian Cardiovascular Journal : Scj. 45: 86-90. PMID 21133820 DOI: 10.3109/14017431.2010.540762  0.309
2011 Cowart D, Aranda J, Haas G, Neutel J, Smith W, Mazhari R, Kalish V, Colucci W. A PHASE I/IIA FIRST IN MAN SAFETY AND TOLERABILITY STUDY OF A NOVEL HNO DONOR, CXL-1020, IN PATIENTS WITH STABLE CONGESTIVE HEART FAILURE Journal of the American College of Cardiology. 57: E299. DOI: 10.1016/S0735-1097(11)60299-4  0.354
2010 Lancel S, Qin F, Lennon SL, Zhang J, Tong X, Mazzini MJ, Kang YJ, Siwik DA, Cohen RA, Colucci WS. Oxidative posttranslational modifications mediate decreased SERCA activity and myocyte dysfunction in Galphaq-overexpressing mice. Circulation Research. 107: 228-32. PMID 20508180 DOI: 10.1161/Circresaha.110.217570  0.611
2010 Jeong MY, Walker JS, Brown RD, Moore RL, Vinson CS, Colucci WS, Long CS. AFos inhibits phenylephrine-mediated contractile dysfunction by altering phospholamban phosphorylation. American Journal of Physiology. Heart and Circulatory Physiology. 298: H1719-26. PMID 20363890 DOI: 10.1152/Ajpheart.00937.2009  0.322
2010 Kuster GM, Lancel S, Zhang J, Communal C, Trucillo MP, Lim CC, Pfister O, Weinberg EO, Cohen RA, Liao R, Siwik DA, Colucci WS. Redox-mediated reciprocal regulation of SERCA and Na+-Ca2+ exchanger contributes to sarcoplasmic reticulum Ca2+ depletion in cardiac myocytes. Free Radical Biology & Medicine. 48: 1182-7. PMID 20132882 DOI: 10.1016/J.Freeradbiomed.2010.01.038  0.483
2010 Qin F, Lennon-Edwards S, Lancel S, Biolo A, Siwik DA, Pimentel DR, Dorn GW, Kang YJ, Colucci WS. Cardiac-specific overexpression of catalase identifies hydrogen peroxide-dependent and -independent phases of myocardial remodeling and prevents the progression to overt heart failure in G(alpha)q-overexpressing transgenic mice. Circulation. Heart Failure. 3: 306-13. PMID 20018955 DOI: 10.1161/Circheartfailure.109.864785  0.428
2010 Calamaras TD, Lee C, Lan F, Ido Y, Siwik D, Colucci W. Oxidant-mediated Post-translational Modifications of the LKB1 Protein in Mediating Cardiac Hypertrophy Free Radical Biology and Medicine. 49: S15-S16. DOI: 10.1016/J.Freeradbiomed.2010.10.008  0.773
2009 Lancel S, Zhang J, Evangelista A, Trucillo MP, Tong X, Siwik DA, Cohen RA, Colucci WS. Nitroxyl activates SERCA in cardiac myocytes via glutathiolation of cysteine 674. Circulation Research. 104: 720-3. PMID 19265039 DOI: 10.1161/Circresaha.108.188441  0.54
2009 Biolo A, Greferath R, Siwik DA, Qin F, Valsky E, Fylaktakidou KC, Pothukanuri S, Duarte CD, Schwarz RP, Lehn JM, Nicolau C, Colucci WS. Enhanced exercise capacity in mice with severe heart failure treated with an allosteric effector of hemoglobin, myo-inositol trispyrophosphate. Proceedings of the National Academy of Sciences of the United States of America. 106: 1926-9. PMID 19204295 DOI: 10.1073/Pnas.0812381106  0.354
2009 Brooks WW, Conrad CH, Robinson KG, Colucci WS, Bing OH. L-arginine fails to prevent ventricular remodeling and heart failure in the spontaneously hypertensive rat. American Journal of Hypertension. 22: 228-34. PMID 19057517 DOI: 10.1038/Ajh.2008.334  0.41
2008 Olshansky B, Sabbah HN, Hauptman PJ, Colucci WS. Parasympathetic nervous system and heart failure: pathophysiology and potential implications for therapy. Circulation. 118: 863-71. PMID 18711023 DOI: 10.1161/Circulationaha.107.760405  0.361
2008 Hare JM, Mangal B, Brown J, Fisher C, Freudenberger R, Colucci WS, Mann DL, Liu P, Givertz MM, Schwarz RP. Impact of oxypurinol in patients with symptomatic heart failure. Results of the OPT-CHF study. Journal of the American College of Cardiology. 51: 2301-9. PMID 18549913 DOI: 10.1016/j.jacc.2008.01.068  0.311
2008 Torre-Amione G, Anker SD, Bourge RC, Colucci WS, Greenberg BH, Hildebrandt P, Keren A, Motro M, Moyé LA, Otterstad JE, Pratt CM, Ponikowski P, Rouleau JL, Sestier F, Winkelmann BR, et al. Results of a non-specific immunomodulation therapy in chronic heart failure (ACCLAIM trial): a placebo-controlled randomised trial. Lancet (London, England). 371: 228-36. PMID 18207018 DOI: 10.1016/S0140-6736(08)60134-8  0.378
2007 Fonarow GC, Lukas MA, Robertson M, Colucci WS, Dargie HJ. Effects of carvedilol early after myocardial infarction: analysis of the first 30 days in Carvedilol Post-Infarct Survival Control in Left Ventricular Dysfunction (CAPRICORN). American Heart Journal. 154: 637-44. PMID 17892984 DOI: 10.1016/J.Ahj.2007.06.002  0.386
2007 Wang TJ, Larson MG, Benjamin EJ, Siwik DA, Safa R, Guo CY, Corey D, Sundstrom J, Sawyer DB, Colucci WS, Vasan RS. Clinical and echocardiographic correlates of plasma procollagen type III amino-terminal peptide levels in the community. American Heart Journal. 154: 291-7. PMID 17643579 DOI: 10.1016/J.Ahj.2007.04.006  0.336
2007 Colucci WS, Kolias TJ, Adams KF, Armstrong WF, Ghali JK, Gottlieb SS, Greenberg B, Klibaner MI, Kukin ML, Sugg JE. Metoprolol reverses left ventricular remodeling in patients with asymptomatic systolic dysfunction: the REversal of VEntricular Remodeling with Toprol-XL (REVERT) trial. Circulation. 116: 49-56. PMID 17576868 DOI: 10.1161/Circulationaha.106.666016  0.35
2007 Shibata R, Izumiya Y, Sato K, Papanicolaou K, Kihara S, Colucci WS, Sam F, Ouchi N, Walsh K. Adiponectin protects against the development of systolic dysfunction following myocardial infarction. Journal of Molecular and Cellular Cardiology. 42: 1065-74. PMID 17499764 DOI: 10.1016/J.Yjmcc.2007.03.808  0.413
2007 Torre-Amione G, Bourge RC, Colucci WS, Greenberg B, Pratt C, Rouleau JL, Sestier F, Moyé LA, Geddes JA, Nemet AJ, Young JB. A study to assess the effects of a broad-spectrum immune modulatory therapy on mortality and morbidity in patients with chronic heart failure: the ACCLAIM trial rationale and design. The Canadian Journal of Cardiology. 23: 369-76. PMID 17440642 DOI: 10.1016/S0828-282X(07)70770-5  0.355
2007 Givertz MM, Andreou C, Conrad CH, Colucci WS. Direct myocardial effects of levosimendan in humans with left ventricular dysfunction: alteration of force-frequency and relaxation-frequency relationships. Circulation. 115: 1218-24. PMID 17339544 DOI: 10.1161/Circulationaha.106.668640  0.382
2007 Biolo A, Qin F, Colucci WS. Is Exercise Capacity Better Than LV Resting Function To Evaluate Interventions in Heart Failure? Journal of Cardiac Failure. 13: S81. DOI: 10.1016/J.Cardfail.2007.06.327  0.36
2006 Kuster GM, Siwik DA, Pimentel DR, Colucci WS. Role of reversible, thioredoxin-sensitive oxidative protein modifications in cardiac myocytes. Antioxidants & Redox Signaling. 8: 2153-9. PMID 17034357 DOI: 10.1089/Ars.2006.8.2153  0.4
2006 Ärnlöv J, Evans JC, Benjamin EJ, Larson MG, Levy D, Sutherland P, Siwik DA, Wang TJ, Colucci WS, Vasan RS. Clinical and echocardiographic correlates of plasma osteopontin in the community: The Framingham Heart Study Heart. 92: 1514-1515. PMID 16973806 DOI: 10.1136/Hrt.2005.081406  0.307
2006 Gheorghiade M, van Veldhuisen DJ, Colucci WS. Contemporary use of digoxin in the management of cardiovascular disorders. Circulation. 113: 2556-64. PMID 16735690 DOI: 10.1161/Circulationaha.105.560110  0.434
2006 Cohn JN, Colucci W. Cardiovascular effects of aldosterone and post-acute myocardial infarction pathophysiology. The American Journal of Cardiology. 97: 4F-12F. PMID 16698330 DOI: 10.1016/j.amjcard.2006.03.004  0.314
2006 Izumiya Y, Shiojima I, Sato K, Sawyer DB, Colucci WS, Walsh K. Vascular endothelial growth factor blockade promotes the transition from compensatory cardiac hypertrophy to failure in response to pressure overload. Hypertension. 47: 887-93. PMID 16567591 DOI: 10.1161/01.Hyp.0000215207.54689.31  0.412
2006 Kotlyar E, Vita JA, Winter MR, Awtry EH, Siwik DA, Keaney JF, Sawyer DB, Cupples LA, Colucci WS, Sam F. The relationship between aldosterone, oxidative stress, and inflammation in chronic, stable human heart failure. Journal of Cardiac Failure. 12: 122-7. PMID 16520260 DOI: 10.1016/J.Cardfail.2005.08.005  0.434
2006 Ahmed A, Rich MW, Love TE, Lloyd-Jones DM, Aban IB, Colucci WS, Adams KF, Gheorghiade M. Digoxin and reduction in mortality and hospitalization in heart failure: a comprehensive post hoc analysis of the DIG trial. European Heart Journal. 27: 178-86. PMID 16339157 DOI: 10.1093/Eurheartj/Ehi687  0.362
2006 Hare JM, Mangal B, Brown J, Fisher C, Freudenberger RS, Colucci WS, Mann DL, Liu P, Givertz MM, Schwarz RP. Efficacy and Safety Study of Oxypurinol Added to Standard Therapy in Patients with New York Heart Association Class III-IV Congestive Heart Failure (The OPT-CHF Trial) Journal of Cardiac Failure. 12: 764. DOI: 10.1016/J.Cardfail.2006.10.009  0.372
2006 Teerlink JR, Packer M, Colucci WS, Young JB, Massie BM, Fisher LD, Huang B, Sarapohja T. Levosimendan Provides Rapid and Sustained Relief in Patient Global Assessment of Acutely Decompensated Heart Failure: The REVIVE II Study Journal of Cardiac Failure. 12: S86. DOI: 10.1016/J.Cardfail.2006.06.291  0.38
2005 Bianchi P, Kunduzova O, Masini E, Cambon C, Bani D, Raimondi L, Seguelas M, Nistri S, Colucci W, Leducq N, Parini A. Oxidative Stress by Monoamine Oxidase Mediates Receptor-Independent Cardiomyocyte Apoptosis by Serotonin and Postischemic Myocardial Injury Circulation. 112: 3297-3305. PMID 16286591 DOI: 10.1161/Circulationaha.104.528133  0.33
2005 Maytin M, Colucci WS. Cardioprotection: a new paradigm in the management of acute heart failure syndromes. The American Journal of Cardiology. 96: 26G-31G. PMID 16181820 DOI: 10.1016/j.amjcard.2005.07.018  0.322
2005 Sam F, Kerstetter DL, Pimental DR, Mulukutla S, Tabaee A, Bristow MR, Colucci WS, Sawyer DB. Increased reactive oxygen species production and functional alterations in antioxidant enzymes in human failing myocardium. Journal of Cardiac Failure. 11: 473-80. PMID 16105639 DOI: 10.1016/J.Cardfail.2005.01.007  0.348
2005 Shiojima I, Sato K, Izumiya Y, Schiekofer S, Ito M, Liao R, Colucci WS, Walsh K. Disruption of coordinated cardiac hypertrophy and angiogenesis contributes to the transition to heart failure. The Journal of Clinical Investigation. 115: 2108-18. PMID 16075055 DOI: 10.1172/Jci24682  0.462
2005 Pfister O, Mouquet F, Jain M, Summer R, Helmes M, Fine A, Colucci WS, Liao R. CD31- but Not CD31+ cardiac side population cells exhibit functional cardiomyogenic differentiation. Circulation Research. 97: 52-61. PMID 15947249 DOI: 10.1161/01.Res.0000173297.53793.Fa  0.345
2005 Bianchi P, Pimentel DR, Murphy MP, Colucci WS, Parini A. A new hypertrophic mechanism of serotonin in cardiac myocytes: receptor-independent ROS generation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 641-3. PMID 15703274 DOI: 10.1096/fj.04-2518fje  0.303
2005 Taniyama Y, Ito M, Sato K, Kuester C, Veit K, Tremp G, Liao R, Colucci WS, Ivashchenko Y, Walsh K, Shiojima I. Akt3 overexpression in the heart results in progression from adaptive to maladaptive hypertrophy. Journal of Molecular and Cellular Cardiology. 38: 375-85. PMID 15698844 DOI: 10.1016/J.Yjmcc.2004.12.002  0.434
2005 Kuster GM, Kotlyar E, Rude MK, Siwik DA, Liao R, Colucci WS, Sam F. Mineralocorticoid receptor inhibition ameliorates the transition to myocardial failure and decreases oxidative stress and inflammation in mice with chronic pressure overload. Circulation. 111: 420-7. PMID 15687129 DOI: 10.1161/01.Cir.0000153800.09920.40  0.373
2005 Trueblood NA, Inscore PR, Brenner D, Lugassy D, Apstein CS, Sawyer DB, Colucci WS. Biphasic temporal pattern in exercise capacity after myocardial infarction in the rat: relationship to left ventricular remodeling. American Journal of Physiology. Heart and Circulatory Physiology. 288: H244-9. PMID 15358607 DOI: 10.1152/Ajpheart.00042.2004  0.301
2004 Shibata R, Ouchi N, Ito M, Kihara S, Shiojima I, Pimentel DR, Kumada M, Sato K, Schiekofer S, Ohashi K, Funahashi T, Colucci WS, Walsh K. Adiponectin-mediated modulation of hypertrophic signals in the heart Nature Medicine. 10: 1384-1389. PMID 15558058 DOI: 10.1038/Nm1137  0.403
2004 Freudenberger RS, Schwarz RP, Brown J, Moore A, Mann D, Givertz MM, Colucci WS, Hare JM. Rationale, design and organisation of an efficacy and safety study of oxypurinol added to standard therapy in patients with NYHA class III - IV congestive heart failure. Expert Opinion On Investigational Drugs. 13: 1509-16. PMID 15500398 DOI: 10.1517/13543784.13.11.1509  0.307
2004 Sundström J, Evans JC, Benjamin EJ, Levy D, Larson MG, Sawyer DB, Siwik DA, Colucci WS, Wilson PW, Vasan RS. Relations of plasma total TIMP-1 levels to cardiovascular risk factors and echocardiographic measures: the Framingham heart study. European Heart Journal. 25: 1509-16. PMID 15342170 DOI: 10.1016/J.Ehj.2004.05.029  0.324
2004 Ito M, Adachi T, Pimentel DR, Ido Y, Colucci WS. Statins inhibit beta-adrenergic receptor-stimulated apoptosis in adult rat ventricular myocytes via a Rac1-dependent mechanism. Circulation. 110: 412-8. PMID 15262848 DOI: 10.1161/01.Cir.0000136088.18960.E6  0.365
2004 Gheorghiade M, Adams KF, Colucci WS. Digoxin in the management of cardiovascular disorders. Circulation. 109: 2959-64. PMID 15210613 DOI: 10.1161/01.Cir.0000132482.95686.87  0.352
2004 Sundström J, Evans JC, Benjamin EJ, Levy D, Larson MG, Sawyer DB, Siwik DA, Colucci WS, Sutherland P, Wilson PW, Vasan RS. Relations of plasma matrix metalloproteinase-9 to clinical cardiovascular risk factors and echocardiographic left ventricular measures: the Framingham Heart Study. Circulation. 109: 2850-6. PMID 15173025 DOI: 10.1161/01.Cir.0000129318.79570.84  0.337
2004 Mann DL, McMurray JJ, Packer M, Swedberg K, Borer JS, Colucci WS, Djian J, Drexler H, Feldman A, Kober L, Krum H, Liu P, Nieminen M, Tavazzi L, van Veldhuisen DJ, et al. Targeted anticytokine therapy in patients with chronic heart failure: results of the Randomized Etanercept Worldwide Evaluation (RENEWAL). Circulation. 109: 1594-602. PMID 15023878 DOI: 10.1161/01.Cir.0000124490.27666.B2  0.391
2004 Vasan RS, Evans JC, Benjamin EJ, Levy D, Larson MG, Sundstrom J, Murabito JM, Sam F, Colucci WS, Wilson PW. Relations of serum aldosterone to cardiac structure: gender-related differences in the Framingham Heart Study. Hypertension. 43: 957-62. PMID 15007028 DOI: 10.1161/01.Hyp.0000124251.06056.8E  0.408
2004 Maytin M, Siwik DA, Ito M, Xiao L, Sawyer DB, Liao R, Colucci WS. Pressure overload-induced myocardial hypertrophy in mice does not require gp91phox. Circulation. 109: 1168-71. PMID 14981002 DOI: 10.1161/01.Cir.0000117229.60628.2F  0.344
2004 Giles TD, Chatterjee K, Cohn JN, Colucci WS, Feldman AM, Ferrans VJ, Roberts R. Definition, classification, and staging of the adult cardiomyopathies: a proposal for revision. Journal of Cardiac Failure. 10: 6-8. PMID 14966768 DOI: 10.1016/S1071-9164(03)00580-3  0.366
2004 Sam F, Xie Z, Ooi H, Kerstetter DL, Colucci WS, Singh M, Singh K. Mice lacking osteopontin exhibit increased left ventricular dilation and reduced fibrosis after aldosterone infusion. American Journal of Hypertension. 17: 188-93. PMID 14751663 DOI: 10.1016/J.Amjhyper.2003.10.007  0.39
2004 Siwik DA, Colucci WS. Regulation of matrix metalloproteinases by cytokines and reactive oxygen/nitrogen species in the myocardium. Heart Failure Reviews. 9: 43-51. PMID 14739767 DOI: 10.1023/B:Hrev.0000011393.40674.13  0.386
2004 Zhao Q, Shen M, Colucci WS, Xiao L. Role of calcium in α1-adrenergic receptor-stimulated hypertrophy in adult rat cardiac myocytes Journal of Cardiac Failure. 10: S91. DOI: 10.1016/J.Cardfail.2004.06.267  0.321
2003 Torre-Amione G, Young JB, Colucci WS, Lewis BS, Pratt C, Cotter G, Stangl K, Elkayam U, Teerlink JR, Frey A, Rainisio M, Kobrin I. Hemodynamic and clinical effects of tezosentan, an intravenous dual endothelin receptor antagonist, in patients hospitalized for acute decompensated heart failure. Journal of the American College of Cardiology. 42: 140-7. PMID 12849674 DOI: 10.1016/S0735-1097(03)00556-4  0.362
2003 Kwon SH, Pimentel DR, Remondino A, Sawyer DB, Colucci WS. H(2)O(2) regulates cardiac myocyte phenotype via concentration-dependent activation of distinct kinase pathways. Journal of Molecular and Cellular Cardiology. 35: 615-21. PMID 12788379 DOI: 10.1016/S0022-2828(03)00084-1  0.307
2003 Gheorghiade M, Colucci WS, Swedberg K. Beta-blockers in chronic heart failure. Circulation. 107: 1570-5. PMID 12668487 DOI: 10.1161/01.Cir.0000065187.80707.18  0.384
2003 COMMUNAL C, SINGH M, MENON B, MARCINKIEWICZ C, CALVETE J, COLUCCI W, SINGH K. 834 Integrins signaling protects adult rat ventricular myocytes from beta-adrenergic receptor-stimulated apoptosis via the activation of ERK1/ European Journal of Heart Failure Supplements. 2: 182. DOI: 10.1016/S1567-4215(03)90555-8  0.303
2003 Packer M, Colucci WS, Fisher L, Massie BM, Teerlink JR, Young JB, Garratt CJ. Development of a comprehensive new endpoint for the evaluation of new treatments for acute decompensated heart failure: results with levosimendan in the REVIVE 1 study Journal of Cardiac Failure. 9: S61. DOI: 10.1016/S1071-9164(03)00532-3  0.366
2003 Shiojima I, Sato K, Colucci WS, Walsh K. Conditional activation of Akt in the heart provides mechanistic insights into progression from compensated cardiac hypertrophy to heart failure Journal of Cardiac Failure. 9: S3. DOI: 10.1016/S1071-9164(03)00155-6  0.482
2003 Vasan RS, Evans JC, Benjamin EJ, Levy D, Larson MG, Sundstrom J, Sam F, Colucci WS, Wilson PW. Serum aldosterone is associated with left ventricular remodeling in women but not men: Framingham heart study Journal of the American College of Cardiology. 41: 195. DOI: 10.1016/S0735-1097(03)81936-8  0.356
2003 Sundstrom J, Benjamin EJ, Evans J, Levy D, Larson M, Sawyer D, Siwik D, Colucci W, Wilson PW, Vasan RS. Tissue inhibitor of metalloproteinases-1 in plasma— relation to left ventricular function and geometry: The Framingham heart study Journal of the American College of Cardiology. 41: 194. DOI: 10.1016/S0735-1097(03)81931-9  0.401
2002 Hare JM, Nguyen GC, Massaro AF, Drazen JM, Stevenson LW, Colucci WS, Fang JC, Johnson W, Givertz MM, Lucas C. Exhaled nitric oxide: a marker of pulmonary hemodynamics in heart failure. Journal of the American College of Cardiology. 40: 1114-9. PMID 12354437 DOI: 10.1016/S0735-1097(02)02117-4  0.416
2002 Ooi H, Colucci WS, Givertz MM. Endothelin mediates increased pulmonary vascular tone in patients with heart failure: demonstration by direct intrapulmonary infusion of sitaxsentan. Circulation. 106: 1618-21. PMID 12270852 DOI: 10.1161/01.Cir.0000034444.31846.F4  0.346
2002 Communal C, Colucci WS, Remondino A, Sawyer DB, Port JD, Wichman SE, Bristow MR, Singh K. Reciprocal modulation of mitogen-activated protein kinases and mitogen-activated protein kinase phosphatase 1 and 2 in failing human myocardium. Journal of Cardiac Failure. 8: 86-92. PMID 12016632 DOI: 10.1054/Jcaf.2002.32755  0.361
2002 Sawyer DB, Siwik DA, Xiao L, Pimentel DR, Singh K, Colucci WS. Role of oxidative stress in myocardial hypertrophy and failure. Journal of Molecular and Cellular Cardiology. 34: 379-88. PMID 11991728 DOI: 10.1006/Jmcc.2002.1526  0.493
2002 Cuffe MS, Califf RM, Adams KF, Benza R, Bourge R, Colucci WS, Massie BM, O'Connor CM, Pina I, Quigg R, Silver MA, Gheorghiade M. Short-term intravenous milrinone for acute exacerbation of chronic heart failure: a randomized controlled trial. Jama. 287: 1541-7. PMID 11911756 DOI: 10.1001/Jama.287.12.1541  0.351
2002 Xiao L, Pimentel DR, Wang J, Singh K, Colucci WS, Sawyer DB. Role of reactive oxygen species and NAD(P)H oxidase in alpha(1)-adrenoceptor signaling in adult rat cardiac myocytes. American Journal of Physiology. Cell Physiology. 282: C926-34. PMID 11880281 DOI: 10.1152/Ajpcell.00254.2001  0.328
2001 Singh K, Xiao L, Remondino A, Sawyer DB, Colucci WS. Adrenergic regulation of cardiac myocyte apoptosis Journal of Cellular Physiology. 189: 257-265. PMID 11748583 DOI: 10.1002/Jcp.10024  0.4
2001 Pimentel DR, Amin JK, Xiao L, Miller T, Viereck J, Oliver-Krasinski J, Baliga R, Wang J, Siwik DA, Singh K, Pagano P, Colucci WS, Sawyer DB. Reactive oxygen species mediate amplitude-dependent hypertrophic and apoptotic responses to mechanical stretch in cardiac myocytes. Circulation Research. 89: 453-60. PMID 11532907 DOI: 10.1161/Hh1701.096615  0.382
2001 Sam F, Sawyer DB, Xie Z, Chang DLF, Ngoy S, Brenner DA, Siwik DA, Singh K, Apstein CS, Colucci WS. Mice lacking inducible nitric oxide synthase have improved left ventricular contractile function and reduced apoptotic cell death late after myocardial infarction Circulation Research. 89: 351-356. PMID 11509452 DOI: 10.1161/Hh1601.094993  0.338
2001 Loh E, Elkayam U, Cody R, Bristow M, Jaski B, Colucci WS. A randomized multicenter study comparing the efficacy and safety of intravenous milrinone and intravenous nitroglycerin in patients with advanced heart failure Journal of Cardiac Failure. 7: 114-121. PMID 11420762 DOI: 10.1054/Jcaf.2001.24136  0.342
2001 Xie Z, Pimentai DR, Lohan S, Vasertriger A, Pligavko C, Colucci WS, Singh K. Regulation of angiotensin II-stimulated osteopontin expression in cardiac microvascular endothelial cells: Role of p42/44 mitogen-activated protein kinase and reactive oxygen species Journal of Cellular Physiology. 188: 132-138. PMID 11382929 DOI: 10.1002/Jcp.1104  0.35
2001 Trueblood NA, Xie Z, Communal C, Sam F, Ngoy S, Liaw L, Jenkins AW, Wang J, Sawyer DB, Bing OHL, Apstein CS, Colucci WS, Singh K. Exaggerated left ventricular dilation and reduced collagen deposition after myocardial infarction in mice lacking osteopontin Circulation Research. 88: 1080-1087. PMID 11375279 DOI: 10.1161/Hh1001.090842  0.373
2001 Givertz MM, Slawsky MT, Moraes DL, McIntyre KM, Colucci WS. Noninvasive determination of pulmonary artery wedge pressure in patients with chronic heart failure. The American Journal of Cardiology. 87: 1213-5; A7. PMID 11356404 DOI: 10.1016/S0002-9149(01)01500-4  0.354
2001 Fowler MB, Vera-Llonch M, Oster G, Bristow MR, Cohn JN, Colucci WS, Gilbert EM, Lukas MA, Lacey MJ, Richner R, Young ST, Packer M. Influence of carvedilol on hospitalizations in heart failure: incidence, resource utilization and costs. U.S. Carvedilol Heart Failure Study Group. Journal of the American College of Cardiology. 37: 1692-9. PMID 11345386 DOI: 10.1016/S0735-1097(01)01190-1  0.376
2001 Yancy CW, Fowler MB, Colucci WS, Gilbert EM, Bristow MR, Cohn JN, Lukas MA, Young ST, Packer M. Race and the response to adrenergic blockade with carvedilol in patients with chronic heart failure New England Journal of Medicine. 344: 1358-1365. PMID 11333992 DOI: 10.1056/Nejm200105033441803  0.378
2001 Jain M, DerSimonian H, Brenner DA, Ngoy S, Teller P, Edge AS, Zawadzka A, Wetzel K, Sawyer DB, Colucci WS, Apstein CS, Liao R. Cell therapy attenuates deleterious ventricular remodeling and improves cardiac performance after myocardial infarction. Circulation. 103: 1920-7. PMID 11294813 DOI: 10.1161/01.Cir.103.14.1920  0.38
2001 Xiao L, Pimental DR, Amin JK, Singh K, Sawyer DB, Colucci WS. MEK1/2-ERK1/2 mediates α1-adrenergic receptor-stimulated hypertrophy in adult rat ventricular myocytes Journal of Molecular and Cellular Cardiology. 33: 779-787. PMID 11273730 DOI: 10.1006/Jmcc.2001.1348  0.323
2001 Colucci WS. Nesiritide for the treatment of decompensated heart failure Journal of Cardiac Failure. 7: 92-100. PMID 11264555 DOI: 10.1054/Jcaf.2001.22999  0.396
2001 Podesser BK, Siwik DA, Eberli FR, Sam F, Ngoy S, Lambert J, Ngo K, Apstein CS, Colucci WS. ETA-receptor blockade prevents matrix metalloproteinase activation late postmyocardial infarction in the rat American Journal of Physiology - Heart and Circulatory Physiology. 280. PMID 11179039 DOI: 10.1152/Ajpheart.2001.280.3.H984  0.303
2001 Givertz MM, Sawyer DB, Colucci WS. Antioxidants and myocardial contractility illuminating the "dark side" of β-adrenergic receptor activation? Circulation. 103: 782-783. PMID 11171781 DOI: 10.1161/01.Cir.103.6.782  0.354
2001 Amin JK, Xiao L, Pimental DR, Pagano PJ, Singh K, Sawyer DB, Colucci WS. Reactive oxygen species mediate alpha-adrenergic receptor-stimulated hypertrophy in adult rat ventricular myocytes Journal of Molecular and Cellular Cardiology. 33: 131-139. PMID 11133229 DOI: 10.1006/Jmcc.2000.1285  0.339
2001 Siwik DA, Pagano PJ, Colucci WS. Oxidative stress regulates collagen synthesis and matrix metalloproteinase activity in cardiac fibroblasts American Journal of Physiology - Cell Physiology. 280. PMID 11121376 DOI: 10.1152/Ajpcell.2001.280.1.C53  0.351
2000 Holubarsch CJF, Colucci WS, Meinertz T, Gaus W, Tendera M. Survival and prognosis: Investigation of Crataegus extract WS 1442 in congestive heart failure (SPICE) - Rationale, study design and study protocol European Journal of Heart Failure. 2: 431-437. PMID 11113721 DOI: 10.1016/S1388-9842(00)00109-4  0.428
2000 Singh K, Communal C, Colucci WS. Inhibition of protein phosphatase 1 induces apoptosis in neonatal rat cardiac myocytes: Role of adrenergic receptor stimulation Basic Research in Cardiology. 95: 389-396. PMID 11099166 DOI: 10.1007/S003950070038  0.345
2000 Satoh N, Suter TM, Liao R, Colucci WS. Chronic α-adrenergic receptor stimulation modulates the contractile phenotype of cardiac myocytes in vitro Circulation. 102: 2249-2254. PMID 11056101 DOI: 10.1161/01.Cir.102.18.2249  0.317
2000 Slawsky MT, Colucci WS, Gottlieb SS, Greenberg BH, Haeusslein E, Hare J, Hutchins S, Leier CV, LeJemtel TH, Loh E, Nicklas J, Ogilby D, Singh BN, Smith W. Acute hemodynamic and clinical effects of levosimendan in patients with severe heart failure. Study Investigators. Circulation. 102: 2222-7. PMID 11056096 DOI: 10.1161/01.Cir.102.18.2222  0.398
2000 Nagata K, Communal C, Lim CC, Jain M, Suter TM, Eberli FR, Satoh N, Colucci WS, Apstein CS, Liao R. Altered β-adrenergic signal transduction in nonfailing hypertrophied myocytes from Dahl salt-sensitive rats American Journal of Physiology - Heart and Circulatory Physiology. 279. PMID 11045988 DOI: 10.1152/Ajpheart.2000.279.5.H2502  0.335
2000 Lim CC, Apstein CS, Colucci WS, Liao R. Impaired cell shortening and relengthening with increased pacing frequency are intrinsic to the senescent mouse cardiomyocyte Journal of Molecular and Cellular Cardiology. 32: 2075-2082. PMID 11040110 DOI: 10.1006/Jmcc.2000.1239  0.324
2000 Colucci WS, Sawyer DB, Singh K, Communal C. Adrenergic overload and apoptosis in heart failure: Implications for therapy Journal of Cardiac Failure. 6: 1-7. PMID 10908092  0.322
2000 Sanders GP, Mendes LA, Colucci WS, Givertz MM. Noninvasive methods for detecting elevated left-sided cardiac filling pressure Journal of Cardiac Failure. 6: 157-164. PMID 10908090 DOI: 10.1016/S1071-9164(00)90018-6  0.401
2000 Sam F, Sawyer DB, Chang DLF, Eberli FR, Ngoy S, Jain M, Amin J, Apstein CS, Colucci WS. Progressive left ventricular remodeling and apoptosis late after myocardial infarction in mouse heart American Journal of Physiology - Heart and Circulatory Physiology. 279. PMID 10899082 DOI: 10.1152/Ajpheart.2000.279.1.H422  0.401
2000 Givertz MM, Colucci WS, LeJemtel TH, Gottlieb SS, Hare JM, Slawsky MT, Leier CV, Loh E, Nicklas JM, Lewis BE. Acute endothelin A receptor blockade causes selective pulmonary vasodilation in patients with chronic heart failure. Circulation. 101: 2922-7. PMID 10869264 DOI: 10.1161/01.Cir.101.25.2922  0.362
2000 Brooks WW, Bing OHL, Boluyt MO, Malhotra A, Morgan JP, Satoh N, Colucci WS, Conrad CH. Altered inotropic responsiveness and gene expression of hypertrophied myocardium with captopril Hypertension. 35: 1203-1209. PMID 10856264 DOI: 10.1161/01.Hyp.35.6.1203  0.358
2000 Bisognano JD, Weinberger HD, Bohlmeyer TJ, Pende A, Raynolds MV, Sastravaha A, Roden R, Asano K, Blaxall BC, Wu SC, Communal C, Singh K, Colucci W, Bristow MR, Port DJ. Myocardial-directed overexpression of the human beta(1)-adrenergic receptor in transgenic mice. Journal of Molecular and Cellular Cardiology. 32: 817-30. PMID 10775486 DOI: 10.1006/Jmcc.2000.1123  0.349
2000 Communal C, Colucci WS, Singh K. p38 mitogen-activated protein kinase pathway protects adult rat ventricular myocytes against β-adrenergic receptor-stimulated apoptosis. Evidence for G(i)-dependent activation Journal of Biological Chemistry. 275: 19395-19400. PMID 10770956 DOI: 10.1074/Jbc.M910471199  0.32
2000 Singh K, Communal C, Sawyer DB, Colucci WS. Adrenergic regulation of myocardial apoptosis Cardiovascular Research. 45: 713-719. PMID 10728393 DOI: 10.1016/S0008-6363(99)00370-3  0.395
2000 Sawyer DB, Colucci WS. Mitochondrial oxidative stress in heart failure: 'Oxygen wastage' revisited Circulation Research. 86: 119-120. PMID 10666404 DOI: 10.1161/01.Res.86.2.119  0.402
2000 Cuffe MS, Califf RM, Adams KF, Bourge RC, Colucci W, Massie B, O'Connor CM, Pina I, Quigg R, Silver M, Robinson LA, Leimberger JD, Gheorghiade M. Rationale and design of the OPTIME CHF trial: Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure American Heart Journal. 139: 15-22. PMID 10618557 DOI: 10.1016/S0002-8703(00)90303-X  0.351
1999 Siwik DA, Tzortzis JD, Pimental DR, Chang DLF, Pagano PJ, Singh K, Sawyer DB, Colucci WS. Inhibition of copper-zinc superoxide dismutase induces cell growth, hypertrophic phenotype, and apoptosis in neonatal rat cardiac myocytes in vitro Circulation Research. 85: 147-153. PMID 10417396 DOI: 10.1161/01.Res.85.2.147  0.413
1999 Packer M, Cohn JN, Abraham WT, Colucci WS, Fowler MB, Greenberg BH, Leier CV, Massie BM, Young JB, Aaronson KD, Abrams J, Adams KF, Alpert JS, Anand IS, Armstrong PW, et al. Consensus recommendations for the management of chronic heart failure: Introduction American Journal of Cardiology. 83: 1A-38A. PMID 10072251 DOI: 10.1016/S0002-9149(98)00850-9  0.364
1999 Singh K, Sirokman G, Communal C, Robinson KG, Conrad CH, Brooks WW, Bing OHL, Colucci WS. Myocardial osteopontin expression coincides with the development of heart failure Hypertension. 33: 663-670. PMID 10024324 DOI: 10.1161/01.Hyp.33.2.663  0.403
1998 Sawyer DB, Colucci WS. Nitric oxide in the failing myocardium Cardiology Clinics. 16: 657-664. PMID 9891595 DOI: 10.1016/S0733-8651(05)70042-4  0.388
1998 Colucci WS. The effects of norepinephrine on myocardial biology: Implications for the therapy of heart failure Clinical Cardiology. 21. PMID 9853191  0.366
1998 Communal C, Singh K, Pimentel DR, Colucci WS. Norepinephrine stimulates apoptosis in adult rat ventricular myocytes by activation of the β-adrenergic pathway Circulation. 98: 1329-1334. PMID 9751683 DOI: 10.1161/01.Cir.98.13.1329  0.363
1998 Givertz MM, Colucci WS. New targets for heart-failure therapy: Endothelin, inflammatory cytokines, and oxidative stress Lancet. 352: 34-38. PMID 9736478 DOI: 10.1016/S0140-6736(98)90017-4  0.472
1998 Hare JM, Givertz MM, Creager MA, Colucci WS. Increased sensitivity to nitric oxide synthase inhibition in patients with heart failure: Potentiation of β-adrenergic inotropic responsiveness Circulation. 97: 161-166. PMID 9445168  0.331
1998 Singh K, Sirokman G, Communal C, Robinson KG, Conrad CH, Brooks WW, Bing OH, Colucci WS. Increased myocardial osteopontin expression coincides with the transition from hypertrophy to failure Journal of Cardiac Failure. 4: 25. DOI: 10.1016/S1071-9164(98)90092-6  0.362
1998 Amin JK, Pimentel DR, Wang J, Chang DL, Pagano PJ, Colucci WS, Sawyer DB. Superoxide anion mediates norepinephrine-induced hypertrophy, but not contractility, in adult rat ventricular myocytes Journal of Cardiac Failure. 4: 19. DOI: 10.1016/S1071-9164(98)90070-7  0.332
1998 Satoh N, Suter TM, Liao R, Colucci WS. α-adrenergic stimulation increases NaCa exchanger through PKC activation and modifies intracellular Ca2+ and contractility in adult rat ventricular myocytes in vitro Journal of Cardiac Failure. 4: 13. DOI: 10.1016/S1071-9164(98)90047-1  0.309
1998 Sam F, Sawyer DB, Ngoy S, Siwik DA, Apstein CS, Colucci WS. Absence of NOS2 does not affect cell death, infarct size or early ventricular remodeling in the infarcted mouse Journal of Cardiac Failure. 4: 10. DOI: 10.1016/S1071-9164(98)90038-0  0.312
1998 Guazzi M, Jain M, Liao R, Suter T, Brenner DA, Ngoy S, Colucci WS, Apstein CS. Exercise intolerance due to increased left ventricular diastolic chamber stiffness in rats with hypertensive hypertrophy Journal of Cardiac Failure. 4: 10. DOI: 10.1016/S1071-9164(98)90036-7  0.313
1998 Sam F, Sawyer DB, Eberli FR, Chang DL, Ngoy S, Apstein CS, Colucci WS. Increased cell death coincides with remodeling late after myocardial infarction in the mouse Journal of Cardiac Failure. 4: 10. DOI: 10.1016/S1071-9164(98)90035-5  0.361
1998 Eberli F, Sam F, Ngoy S, Chang D, Apstein C, Colucci W. Progressive molecular and physiologic remodeling in murine hearts after myocardial infarction Journal of the American College of Cardiology. 31: 288. DOI: 10.1016/S0735-1097(98)81897-4  0.418
1998 Sam F, Eberli F, Ngoy S, Sivvik D, Chang D, Apstein C, Colucci W. Expression of the inducible isoform of nitric oxide synthase in murine myocardium following a myocardial infarction Journal of the American College of Cardiology. 31: 187. DOI: 10.1016/S0735-1097(98)81453-8  0.346
1998 Moraes D, Dobroski D, Awtry E, Mcintyre K, Slawsky M, Givertz M, Colucci W. A noninvasive method for predicting pulmonary capillary wedge pressure in patients with heart failure Journal of the American College of Cardiology. 31: 430. DOI: 10.1016/S0735-1097(98)80217-9  0.358
1997 Colucci WS. Molecular and cellular mechanisms of myocardial failure American Journal of Cardiology. 80. PMID 9412539 DOI: 10.1016/S0002-9149(97)00845-X  0.458
1997 Cohn JN, Fowler MB, Bristow MR, Colucci WS, Gilbert EM, Kinhal V, Krueger SK, Lejemtel T, Narahara KA, Packer M, Young ST, Holcslaw TL, Lukas MA. Safety and efficacy of carvedilol in severe heart failure Journal of Cardiac Failure. 3: 173-179. PMID 9330125 DOI: 10.1016/S1071-9164(97)90013-0  0.408
1997 Givertz MM, Hare JM, Loh E, Gauthier DF, Colucci WS. Effect of bolus milrinone on hemodynamic variables and pulmonary vascular resistance in patients with severe left ventricular dysfunction: A rapid test for reversibility of pulmonary hypertension Journal of the American College of Cardiology. 28: 1775-1780. PMID 8962566 DOI: 10.1016/S0735-1097(96)00399-3  0.417
1996 Keaney JF, Hare JM, Balligand JL, Loscalzo J, Smith TW, Colucci WS. Inhibition of nitric oxide synthase augments myocardial contractile responses to beta-adrenergic stimulation. The American Journal of Physiology. 271: H2646-52. PMID 8997327 DOI: 10.1152/Ajpheart.1996.271.6.H2646  0.348
1996 Moye LA, Abernethy D, Von Olshausen K, Pop T, Berger J, Packer M, Cohn JN, Colucci WS. Carvedilol in patients with chronic heart failure [1] New England Journal of Medicine. 335: 1318-1320. PMID 8992328 DOI: 10.1056/Nejm199610243351711  0.392
1996 Newton GE, Parker AB, Landzberg JS, Colucci WS, Parker JD. Muscarinic receptor modulation of basal and beta-adrenergic stimulated function of the failing human left ventricle. The Journal of Clinical Investigation. 98: 2756-63. PMID 8981921 DOI: 10.1172/Jci119101  0.416
1996 Colucci WS, Packer M, Bristow MR, Gilbert EM, Cohn JN, Fowler MB, Krueger SK, Hershberger R, Uretsky BF, Bowers JA, Sackner-Bernstein JD, Young ST, Holcslaw TL, Lukas MA. Carvedilol inhibits clinical progression in patients with mild symptoms of heart failure Circulation. 94: 2800-2806. PMID 8941105 DOI: 10.1161/01.Cir.94.11.2800  0.433
1996 Packer M, Colucci WS, Sackner-Bernstein JD, Liang CS, Goldscher DA, Freeman I, Kukin ML, Kinhal V, Udelson JE, Klapholz M, Gottlieb SS, Pearle D, Cody RJ, Gregory JJ, Kantrowitz NE, et al. Double-blind, placebo-controlled study of the effects of carvedilol in patients with moderate to severe heart failure: The PRECISE Trial Circulation. 94: 2793-2799. PMID 8941104 DOI: 10.1161/01.Cir.94.11.2793  0.402
1996 Colucci WS. Myocardial endothelin: Does it play a role in myocardial failure? Circulation. 93: 1069-1072. PMID 8653824 DOI: 10.1161/01.Cir.93.6.1069  0.378
1996 Hare JM, Givertz MM, Creage MA, Colucci WS. Role of nitric oxide in parasympathetic modulation of β-adrenergic inotropic responses in humans with heart failure Journal of the American College of Cardiology. 27: 202. DOI: 10.1016/S0735-1097(96)81669-X  0.394
1996 Cohn JN, Fowler MB, Bristow MA, Colucci WS, Gilbert E, Kinal V, Krueger SK, LeJemtel T, Narahara KA, Packer M. Effect of carvedilol in severe chronic heart failure Journal of the American College of Cardiology. 27: 169. DOI: 10.1016/S0735-1097(96)80907-7  0.397
1996 Fowler MB, Gilbert E, Cohn JN, Bristow MA, Colucci WS, Shusterman NH, Packer M. Effects of carvedilol on cardiovascular hospitalizations in patients with chronic heart failure Journal of the American College of Cardiology. 27: 169. DOI: 10.1016/S0735-1097(96)80906-5  0.387
1996 Hare JM, Massaro AF, Drazen JM, Colucci WS. Exhaled nitric oxide as a measure of response to therapy in patients with heart failure Journal of the American College of Cardiology. 27: 70. DOI: 10.1016/S0735-1097(96)80478-5  0.394
1995 Levy AP, Levy NS, Loscalzo J, Calderone A, Takahashi N, Yeo KT, Koren G, Colucci WS, Goldberg MA. Regulation of vascular endothelial growth factor in cardiac myocytes. Circulation Research. 76: 758-66. PMID 7728992 DOI: 10.1161/01.Res.76.5.758  0.332
1995 Parker JD, Newton GE, Landzberg JS, Floras JS, Colucci WS. Functional significance of presynaptic α-adrenergic receptors in failing and nonfailing human left ventricle Circulation. 92: 1793-1800. PMID 7671363 DOI: 10.1161/01.Cir.92.7.1793  0.403
1995 Hare JM, Colucci WS. Role of nitric oxide in the regulation of myocardial function Progress in Cardiovascular Diseases. 38: 155-166. PMID 7568904 DOI: 10.1016/S0033-0620(05)80004-0  0.333
1994 Loh E, Stamler JS, Hare JM, Loscalzo J, Colucci WS. Cardiovascular effects of inhaled nitric oxide in patients with left ventricular dysfunction Circulation. 90: 2780-2785. PMID 7994821 DOI: 10.1161/01.Cir.90.6.2780  0.313
1993 Loh E, Colucci WS, Mudge GH. Cardiac Transplantation in the 1990s Cardiology in Review. 1: 218-227. DOI: 10.1097/00045415-199301040-00004  0.306
1993 Colucci WS. Search for an Effective and Safe Orally Active Positive Inotropic Drug for Treatment of Heart Failure Cardiology in Review. 1: 42-49. DOI: 10.1097/00045415-199301010-00006  0.369
1991 Colucci WS. Cardiovascular effects of milrinone. American Heart Journal. 121: 1945-7. PMID 2035424 DOI: 10.1016/0002-8703(91)90829-7  0.316
1991 Parker JD, Landzberg JS, Bittl JA, Colucci WS. Myocardial α-adrenergic tone impairs isovolumic relaxation in the failing human left ventricle Journal of the American College of Cardiology. 17: A295. DOI: 10.1016/0735-1097(91)92148-F  0.311
1990 Creager MA, Quigg RJ, Ren C, Meek MA, Colucci WS. Limb vasodilator responsiveness to isoproterenol in congestive heart failure Journal of the American College of Cardiology. 15: A257. DOI: 10.1016/0735-1097(90)92744-M  0.398
1989 Colucci WS. Myocardial and vascular actions of milrinone. European Heart Journal. 32-8. PMID 2680495 DOI: 10.1093/eurheartj/10.suppl_C.32  0.306
1989 Colucci WS, Parker JD. Effects of β-Adrenergic Agents on Systolic and Diastolic Myocardial Function in Patients With and Without Heart Failure Journal of Cardiovascular Pharmacology. 14: S28-S37. DOI: 10.1097/00005344-198900145-00006  0.305
1987 Ludmer PL, Baim DS, Antman EM, Gauthier DF, Rocco MB, Friedman PL, Colucci WS. Effects of milrinone on complex ventricular arrhythmias in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. The American Journal of Cardiology. 59: 1351-5. PMID 3591690 DOI: 10.1016/0002-9149(87)90918-0  0.303
1987 Colucci WS. Usefulness of calcium antagonists for congestive heart failure. The American Journal of Cardiology. 59: 52B-58B. PMID 3544790 DOI: 10.1016/0002-9149(87)90082-8  0.327
1986 Ludmer PL, Wright RF, Arnold JM, Ganz P, Braunwald E, Colucci WS. Separation of the direct myocardial and vasodilator actions of milrinone administered by an intracoronary infusion technique. Circulation. 73: 130-7. PMID 3940664 DOI: 10.1161/01.Cir.73.1.130  0.381
1986 Arnold JM, Ludmer PL, Wright RF, Ganz P, Braunwald E, Colucci WS. Role of reflex sympathetic withdrawal in the hemodynamic response to an increased inotropic state in patients with severe heart failure. Journal of the American College of Cardiology. 8: 413-8. PMID 3734263 DOI: 10.1016/S0735-1097(86)80060-2  0.372
1986 Colucci WS, Wright RF, Braunwald E. New positive inotropic agents in the treatment of congestive heart failure. Mechanisms of action and recent clinical developments. 1. The New England Journal of Medicine. 314: 290-9. PMID 2867470 DOI: 10.1056/Nejm198601303140506  0.335
1986 Colucci WS, Wright RF, Braunwald E. New positive inotropic agents in the treatment of congestive heart failure. Mechanisms of action and recent clinical developments. 2. The New England Journal of Medicine. 314: 349-58. PMID 2418353 DOI: 10.1056/Nejm198602063140605  0.373
1985 Colucci WS, Fifer MA, Lorell BH, Wynne J. Calcium channel blockers in congestive heart failure: theoretic considerations and clinical experience. The American Journal of Medicine. 78: 9-17. PMID 3976695 DOI: 10.1016/0002-9343(85)90164-0  0.351
1985 Fifer MA, Colucci WS, Lorell BH, Jaski BE, Barry WH. Inotropic, vascular and neuroendocrine effects of nifedipine in heart failure: comparison with nitroprusside. Journal of the American College of Cardiology. 5: 731-7. PMID 3973272 DOI: 10.1016/S0735-1097(85)80402-2  0.419
1985 Jaski BE, Fifer MA, Wright RF, Braunwald E, Colucci WS. Positive inotropic and vasodilator actions of milrinone in patients with severe congestive heart failure. Dose-response relationships and comparison to nitroprusside. The Journal of Clinical Investigation. 75: 643-9. PMID 3973022 DOI: 10.1172/Jci111742  0.384
1984 Monrad ES, McKay RG, Baim DS, Colucci WS, Fifer MA, Heller GV, Royal HD, Grossman W. Improvement in indexes of diastolic performance in patients with congestive heart failure treated with milrinone. Circulation. 70: 1030-7. PMID 6499142 DOI: 10.1161/01.Cir.70.6.1030  0.38
1984 Braunwald E, Colucci WS. Vasodilator therapy of heart failure. Has the promissory note been paid? The New England Journal of Medicine. 310: 459-61. PMID 6363928 DOI: 10.1056/Nejm198402163100711  0.361
1982 Colucci WS, Lorell BH, Schoen FJ, Warhol MJ, Grossman W. Hypertrophic obstructive cardiomyopathy due to Fabry's disease. The New England Journal of Medicine. 307: 926-8. PMID 6810178 DOI: 10.1056/Nejm198210073071505  0.356
1981 Rude RE, Turi Z, Brown EJ, Lorell BH, Colucci WS, Mudge GH, Taylor CR, Grossman W. Acute effects of oral pirbuterol on myocardial oxygen metabolism and systemic hemodynamics in chronic congestive heart failure. Circulation. 64: 139-45. PMID 7237712 DOI: 10.1161/01.Cir.64.1.139  0.399
1981 Dzau VJ, Colucci WS, Hollenberg NK, Williams GH. Relation of the renin-angiotensin-aldosterone system to clinical state in congestive heart failure. Circulation. 63: 645-51. PMID 7006851 DOI: 10.1161/01.Cir.63.3.645  0.381
1981 Colucci WS, Williams GH, Alexander RW, Braunwald E. Mechanisms and implications of vasodilator tolerance in the treatment of congestive heart failure. The American Journal of Medicine. 71: 89-99. PMID 6166194 DOI: 10.1016/0002-9343(81)90263-1  0.404
1981 Colucci WS, Alexander RW, Mudge GH, Rude RE, Holman BL, Wynne J, Grossman W, Braunwald E. Acute and chronic effects of pirbuterol on left ventricular ejection fraction and clinical status in severe congestive heart failure. American Heart Journal. 102: 564-8. PMID 6115573 DOI: 10.1016/0002-8703(81)90745-6  0.312
1981 Colucci WS, Holman BL, Wynne J, Carabello B, Malacoff R, Grossman W, Braunwald E. Improved right ventricular function and reduced pulmonary vascular resistance during prazosin therapy of congestive heart failure. The American Journal of Medicine. 71: 75-80. PMID 6113759 DOI: 10.1016/0002-9343(81)90261-8  0.391
1981 Colucci WS, Alexander RW, Williams GH, Rude RE, Holman BL, Konstam MA, Wynne J, Mudge GH, Braunwald E. Decreased lymphocyte beta-adrenergic-receptor density in patients with heart failure and tolerance to the beta-adrenergic agonist pirbuterol. The New England Journal of Medicine. 305: 185-90. PMID 6113543 DOI: 10.1056/Nejm198107233050402  0.393
1980 Dzau VJ, Colucci WS, Williams GH, Curfman G, Meggs L, Hollenberg NK. Sustained effectiveness of converting-enzyme inhibition in patients with severe congestive heart failure. The New England Journal of Medicine. 302: 1373-9. PMID 6246425 DOI: 10.1056/Nejm198006193022501  0.415
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