Adi Kimchi - Publications

Affiliations: 
Weizmann Institute of Science, Rehovot, Israel 
Area:
Cell Biology, Molecular Biology, Biochemistry

149 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Vitale I, Pietrocola F, Guilbaud E, Aaronson SA, Abrams JM, Adam D, Agostini M, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Aqeilan RI, Arama E, Baehrecke EH, ... ... Kimchi A, et al. Apoptotic cell death in disease-Current understanding of the NCCD 2023. Cell Death and Differentiation. PMID 37100955 DOI: 10.1038/s41418-023-01153-w  0.378
2022 Hammer L, Levin-Salomon V, Yaeli-Slonim N, Weiss M, Dekel-Bird NP, Olender T, Porat Z, Winograd-Katz S, Savidor A, Levin Y, Bialik S, Geiger B, Kimchi A. A new function for the serine protease HtrA2 in controlling radiation-induced senescence in cancer cells. Molecular Oncology. 16: 1365-1383. PMID 35122388 DOI: 10.1002/1878-0261.13187  0.334
2020 Wu YH, Chou TF, Young L, Hsieh FY, Pan HY, Mo ST, Brown SB, Chen RH, Kimchi A, Lai MZ. Tumor suppressor death-associated protein kinase 1 inhibits necroptosis by p38 MAPK activation. Cell Death & Disease. 11: 305. PMID 32366830 DOI: 10.1038/S41419-020-2534-9  0.542
2019 Srivastava S, Nataraj NB, Sekar A, Ghosh S, Bornstein C, Drago-Garcia D, Roth L, Romaniello D, Marrocco I, David E, Gilad Y, Lauriola M, Rotkopf R, Kimchi A, Haga Y, et al. ETS Proteins Bind with Glucocorticoid Receptors: Relevance for Treatment of Ewing Sarcoma. Cell Reports. 29: 104-117.e4. PMID 31577941 DOI: 10.1016/J.Celrep.2019.08.088  0.367
2019 Shiloh R, Bialik S, Kimchi A. Ser289 phosphorylation activates both DAPK1 and DAPK2 but in response to different intracellular signaling pathways. Cell Cycle (Georgetown, Tex.). 18: 1169-1176. PMID 31116076 DOI: 10.1080/15384101.2019.1617616  0.431
2019 Hammer L, Levin-Salomon V, Kimchi A. The Critical Role of Programmed Cell Death Proteins in Radiation-Induced Senescence International Journal of Radiation Oncology*Biology*Physics. 105: E681-E682. DOI: 10.1016/j.ijrobp.2019.06.1005  0.311
2018 Nuta GC, Gilad Y, Gershoni M, Sznajderman A, Schlesinger T, Bialik S, Eisenstein M, Pietrokovski S, Kimchi A. A cancer associated somatic mutation in LC3B attenuates its binding to E1-like ATG7 protein and subsequent lipidation. Autophagy. PMID 30238850 DOI: 10.1080/15548627.2018.1525476  0.346
2018 Bialik S, Dasari SK, Kimchi A. Autophagy-dependent cell death - where, how and why a cell eats itself to death. Journal of Cell Science. 131. PMID 30237248 DOI: 10.1242/Jcs.215152  0.484
2018 Shiloh R, Kimchi A. AMPK activates DAPK2 to promote autophagy. Oncotarget. 9: 31570-31571. PMID 30167079 DOI: 10.18632/Oncotarget.25842  0.363
2018 Shiloh R, Gilad Y, Ber Y, Eisenstein M, Aweida D, Bialik S, Cohen S, Kimchi A. Non-canonical activation of DAPK2 by AMPK constitutes a new pathway linking metabolic stress to autophagy. Nature Communications. 9: 1759. PMID 29717115 DOI: 10.1038/S41467-018-03907-4  0.475
2018 Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, ... ... Kimchi A, et al. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell Death and Differentiation. PMID 29362479 DOI: 10.1038/S41418-017-0012-4  0.478
2017 Dasari SK, Schejter E, Bialik S, Shkedy A, Levin-Salomon V, Levin-Zaidman S, Kimchi A. Death by over-eating: The Gaucher Disease associated gene GBA1, identified in a screen for mediators of autophagic cell death, is necessary for developmental cell death in Drosophila midgut. Cell Cycle (Georgetown, Tex.). 0. PMID 28933588 DOI: 10.1080/15384101.2017.1380134  0.475
2017 Dasari SK, Bialik S, Levin-Zaidman S, Levin-Salomon V, Merrill AH, Futerman AH, Kimchi A. Signalome-wide RNAi screen identifies GBA1 as a positive mediator of autophagic cell death. Cell Death and Differentiation. PMID 28574511 DOI: 10.1038/Cdd.2017.80  0.5
2017 Hay-Koren A, Bialik S, Levin-Salomon V, Kimchi A. Changes in cIAP2, survivin and BimEL expression characterize the switch from autophagy to apoptosis in prolonged starvation. Journal of Internal Medicine. 281: 458-470. PMID 28425584 DOI: 10.1111/Joim.12616  0.443
2016 Yoffe Y, David M, Kalaora R, Povodovski L, Friedlander G, Feldmesser E, Ainbinder E, Saada A, Bialik S, Kimchi A. Cap-independent translation by DAP5 controls cell fate decisions in human embryonic stem cells. Genes & Development. 30: 1991-2004. PMID 27664238 DOI: 10.1101/Gad.285239.116  0.42
2016 Chou TF, Chuang YT, Hsieh WC, Chang PY, Liu HY, Mo ST, Hsu TS, Miaw SC, Chen RH, Kimchi A, Lai MZ. Tumour suppressor death-associated protein kinase targets cytoplasmic HIF-1α for Th17 suppression. Nature Communications. 7: 11904. PMID 27312851 DOI: 10.1038/Ncomms11904  0.347
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin J, Abeliovich H, Arozena AA, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Kimchi A, et al. Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 Autophagy. 12: 443-443. PMID 26902590 DOI: 10.1080/15548627.2016.1147886  0.702
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Kimchi A, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.77
2015 Liberman N, Gandin V, Svitkin YV, David M, Virgili G, Jaramillo M, Holcik M, Nagar B, Kimchi A, Sonenberg N. DAP5 associates with eIF2β and eIF4AI to promote Internal Ribosome Entry Site driven translation. Nucleic Acids Research. 43: 3764-75. PMID 25779044 DOI: 10.1093/Nar/Gkv205  0.347
2015 Ber Y, Shiloh R, Gilad Y, Degani N, Bialik S, Kimchi A. DAPK2 is a novel regulator of mTORC1 activity and autophagy. Cell Death and Differentiation. 22: 465-75. PMID 25361081 DOI: 10.1038/Cdd.2014.177  0.516
2014 Gilad Y, Kimchi A. The programmed cell death GLuc PCA library - a powerful tool for pathway discovery and drug screening. Molecular & Cellular Oncology. 1: e969644. PMID 27308378 DOI: 10.4161/23723548.2014.969644  0.428
2014 Gilad Y, Shiloh R, Ber Y, Bialik S, Kimchi A. Discovering protein-protein interactions within the programmed cell death network using a protein-fragment complementation screen. Cell Reports. 8: 909-21. PMID 25066129 DOI: 10.1016/J.Celrep.2014.06.049  0.47
2014 Levin-Salomon V, Bialik S, Kimchi A. DAP-kinase and autophagy. Apoptosis : An International Journal On Programmed Cell Death. 19: 346-56. PMID 24264886 DOI: 10.1007/S10495-013-0918-3  0.517
2014 Bialik S, Kimchi A. The DAP-kinase interactome. Apoptosis : An International Journal On Programmed Cell Death. 19: 316-28. PMID 24220855 DOI: 10.1007/S10495-013-0926-3  0.512
2014 Shiloh R, Bialik S, Kimchi A. The DAPK family: a structure-function analysis. Apoptosis : An International Journal On Programmed Cell Death. 19: 286-97. PMID 24220854 DOI: 10.1007/S10495-013-0924-5  0.427
2014 Weingarten-Gabbay S, Khan D, Liberman N, Yoffe Y, Bialik S, Das S, Oren M, Kimchi A. The translation initiation factor DAP5 promotes IRES-driven translation of p53 mRNA Oncogene. 33: 611-618. PMID 23318444 DOI: 10.1038/Onc.2012.626  0.361
2012 Rubinstein AD, Kimchi A. Life in the balance - a mechanistic view of the crosstalk between autophagy and apoptosis. Journal of Cell Science. 125: 5259-68. PMID 23377657 DOI: 10.1242/Jcs.115865  0.514
2012 Koren I, Kimchi A. Cell biology. Promoting tumorigenesis by suppressing autophagy. Science (New York, N.Y.). 338: 889-90. PMID 23161981 DOI: 10.1126/Science.1230577  0.426
2012 Bialik S, Kimchi A. Biochemical and functional characterization of the ROC domain of DAPK establishes a new paradigm of GTP regulation in ROCO proteins. Biochemical Society Transactions. 40: 1052-7. PMID 22988864 DOI: 10.1042/Bst20120155  0.454
2012 Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Kimchi A, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496  0.356
2012 Eisenberg-Lerner A, Kimchi A. DAPk silencing by DNA methylation conveys resistance to anti EGFR drugs in lung cancer cells. Cell Cycle (Georgetown, Tex.). 11: 2051. PMID 22622084 DOI: 10.4161/Cc.20538  0.704
2012 Eisenberg-Lerner A, Kimchi A. PKD at the crossroads of necrosis and autophagy. Autophagy. 8: 433-4. PMID 22302000 DOI: 10.4161/Auto.19288  0.786
2012 Mor I, Bialik S, Kimchi A. DAPk and pyruvate kinase: unlikely partners in cancer metabolic regulation. Cell Cycle (Georgetown, Tex.). 11: 3-4. PMID 22157095 DOI: 10.4161/Cc.11.1.18653  0.319
2012 Eisenberg-Lerner A, Kimchi A. PKD is a kinase of Vps34 that mediates ROS-induced autophagy downstream of DAPk. Cell Death and Differentiation. 19: 788-97. PMID 22095288 DOI: 10.1038/Cdd.2011.149  0.8
2012 Nakav S, Cohen S, Feigelson SW, Bialik S, Shoseyov D, Kimchi A, Alon R. Tumor suppressor death-associated protein kinase attenuates inflammatory responses in the lung. American Journal of Respiratory Cell and Molecular Biology. 46: 313-22. PMID 21997486 DOI: 10.1165/Rcmb.2011-0181Oc  0.326
2012 Mor I, Carlessi R, Ast T, Feinstein E, Kimchi A. Death-associated protein kinase increases glycolytic rate through binding and activation of pyruvate kinase Oncogene. 31: 683-693. PMID 21725354 DOI: 10.1038/Onc.2011.264  0.511
2011 Rubinstein AD, Eisenstein M, Ber Y, Bialik S, Kimchi A. The autophagy protein Atg12 associates with antiapoptotic Bcl-2 family members to promote mitochondrial apoptosis. Molecular Cell. 44: 698-709. PMID 22152474 DOI: 10.1016/J.Molcel.2011.10.014  0.515
2011 Yosef N, Zalckvar E, Rubinstein AD, Homilius M, Atias N, Vardi L, Berman I, Zur H, Kimchi A, Ruppin E, Sharan R. ANAT: a tool for constructing and analyzing functional protein networks. Science Signaling. 4: pl1. PMID 22028466 DOI: 10.1126/Scisignal.2001935  0.696
2011 Carlessi R, Levin-Salomon V, Ciprut S, Bialik S, Berissi H, Albeck S, Peleg Y, Kimchi A. GTP binding to the ROC domain of DAP-kinase regulates its function through intramolecular signalling. Embo Reports. 12: 917-23. PMID 21738225 DOI: 10.1038/Embor.2011.126  0.424
2011 Bialik S, Kimchi A. Pin-pointing a new DAP kinase function: the peptidyl-proly isomerase Pin1 Is Negatively Regulated by DAP kinase-mediated phosphorylation. Molecular Cell. 42: 139-41. PMID 21504826 DOI: 10.1016/J.Molcel.2011.04.002  0.405
2011 Shoval Y, Berissi H, Kimchi A, Pietrokovski S. New modularity of DAP-kinases: alternative splicing of the DRP-1 gene produces a ZIPk-like isoform. Plos One. 6: e17344. PMID 21408167 DOI: 10.1371/Journal.Pone.0017344  0.813
2011 Bialik S, Pietrokovski S, Kimchi A. Myosin drives autophagy in a pathway linking Atg1 to Atg9. The Embo Journal. 30: 629-30. PMID 21326172 DOI: 10.1038/Emboj.2011.8  0.42
2011 Wu PR, Tsai PI, Chen GC, Chou HJ, Huang YP, Chen YH, Lin MY, Kimchi A, Chien CT, Chen RH. DAPK activates MARK1/2 to regulate microtubule assembly, neuronal differentiation, and tau toxicity. Cell Death and Differentiation. 18: 1507-20. PMID 21311567 DOI: 10.1038/Cdd.2011.2  0.423
2011 Paz A, Brownstein Z, Ber Y, Bialik S, David E, Sagir D, Ulitsky I, Elkon R, Kimchi A, Avraham KB, Shiloh Y, Shamir R. SPIKE: a database of highly curated human signaling pathways. Nucleic Acids Research. 39: D793-9. PMID 21097778 DOI: 10.1093/Nar/Gkq1167  0.344
2011 Lai M, Chuang Y, Chou T, Lin K, Chen R, Miau S, Kimchi A. CS18-2. Inhibition of Th17 differentiation and EAE development by tumor suppressor death-associated protein kinase Cytokine. 56: 109. DOI: 10.1016/J.Cyto.2011.07.423  0.401
2010 Guenebeaud C, Goldschneider D, Castets M, Guix C, Chazot G, Delloye-Bourgeois C, Eisenberg-Lerner A, Shohat G, Zhang M, Laudet V, Kimchi A, Bernet A, Mehlen P. The dependence receptor UNC5H2/B triggers apoptosis via PP2A-mediated dephosphorylation of DAP kinase. Molecular Cell. 40: 863-76. PMID 21172653 DOI: 10.1016/J.Molcel.2010.11.021  0.795
2010 Koren I, Reem E, Kimchi A. Autophagy gets a brake: DAP1, a novel mTOR substrate, is activated to suppress the autophagic process. Autophagy. 6: 1179-80. PMID 20818178 DOI: 10.4161/Auto.6.8.13338  0.82
2010 Zalckvar E, Bialik S, Kimchi A. The road not taken: a systems level strategy for analyzing the cell death network. Autophagy. 6: 813-5. PMID 20574161 DOI: 10.4161/Auto.6.6.12589  0.756
2010 Bialik S, Zalckvar E, Ber Y, Rubinstein AD, Kimchi A. Systems biology analysis of programmed cell death. Trends in Biochemical Sciences. 35: 556-64. PMID 20537543 DOI: 10.1016/J.Tibs.2010.04.008  0.727
2010 Koren I, Reem E, Kimchi A. DAP1, a novel substrate of mTOR, negatively regulates autophagy. Current Biology : Cb. 20: 1093-8. PMID 20537536 DOI: 10.1016/J.Cub.2010.04.041  0.828
2010 Zalckvar E, Yosef N, Reef S, Ber Y, Rubinstein AD, Mor I, Sharan R, Ruppin E, Kimchi A. A systems level strategy for analyzing the cell death network: implication in exploring the apoptosis/autophagy connection. Cell Death and Differentiation. 17: 1244-53. PMID 20150916 DOI: 10.1038/cdd.2010.7  0.816
2010 Bialik S, Kimchi A. Lethal weapons: DAP-kinase, autophagy and cell death: DAP-kinase regulates autophagy. Current Opinion in Cell Biology. 22: 199-205. PMID 20005690 DOI: 10.1016/J.Ceb.2009.11.004  0.549
2009 Zalckvar E, Berissi H, Eisenstein M, Kimchi A. Phosphorylation of Beclin 1 by DAP-kinase promotes autophagy by weakening its interactions with Bcl-2 and Bcl-XL. Autophagy. 5: 720-2. PMID 19395874 DOI: 10.4161/Auto.5.5.8625  0.772
2009 Galluzzi L, Aaronson SA, Abrams J, Alnemri ES, Andrews DW, Baehrecke EH, Bazan NG, Blagosklonny MV, Blomgren K, Borner C, Bredesen DE, Brenner C, Castedo M, Cidlowski JA, Ciechanover A, ... ... Kimchi A, et al. Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell Death and Differentiation. 16: 1093-107. PMID 19373242 DOI: 10.1038/Cdd.2009.44  0.441
2009 Eisenberg-Lerner A, Bialik S, Simon HU, Kimchi A. Life and death partners: apoptosis, autophagy and the cross-talk between them. Cell Death and Differentiation. 16: 966-75. PMID 19325568 DOI: 10.1038/cdd.2009.33  0.794
2009 Yosef N, Ungar L, Zalckvar E, Kimchi A, Kupiec M, Ruppin E, Sharan R. Toward accurate reconstruction of functional protein networks. Molecular Systems Biology. 5: 248. PMID 19293828 DOI: 10.1038/Msb.2009.3  0.713
2009 Zalckvar E, Berissi H, Mizrachy L, Idelchuk Y, Koren I, Eisenstein M, Sabanay H, Pinkas-Kramarski R, Kimchi A. DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy. Embo Reports. 10: 285-92. PMID 19180116 DOI: 10.1038/Embor.2008.246  0.798
2009 Eisenberg-Lerner A, Kimchi A. The paradox of autophagy and its implication in cancer etiology and therapy. Apoptosis : An International Journal On Programmed Cell Death. 14: 376-91. PMID 19172397 DOI: 10.1007/S10495-008-0307-5  0.782
2009 Liberman N, Marash L, Kimchi A. The translation initiation factor DAP5 is a regulator of cell survival during mitosis. Cell Cycle (Georgetown, Tex.). 8: 204-9. PMID 19158497 DOI: 10.4161/Cc.8.2.7384  0.832
2008 Gozuacik D, Bialik S, Raveh T, Mitou G, Shohat G, Sabanay H, Mizushima N, Yoshimori T, Kimchi A. DAP-kinase is a mediator of endoplasmic reticulum stress-induced caspase activation and autophagic cell death. Cell Death and Differentiation. 15: 1875-86. PMID 18806755 DOI: 10.1038/Cdd.2008.121  0.784
2008 Liberman N, Dym O, Unger T, Albeck S, Peleg Y, Jacobovitch Y, Branzburg A, Eisenstein M, Marash L, Kimchi A. The crystal structure of the C-terminal DAP5/p97 domain sheds light on the molecular basis for its processing by caspase cleavage. Journal of Molecular Biology. 383: 539-48. PMID 18722383 DOI: 10.1016/J.Jmb.2008.08.013  0.802
2008 Reef S, Kimchi A. Nucleolar p19ARF, unlike mitochondrial smARF, is incapable of inducing p53-independent autophagy. Autophagy. 4: 866-9. PMID 18719357 DOI: 10.4161/Auto.6691  0.655
2008 Marash L, Liberman N, Henis-Korenblit S, Sivan G, Reem E, Elroy-Stein O, Kimchi A. DAP5 promotes cap-independent translation of Bcl-2 and CDK1 to facilitate cell survival during mitosis. Molecular Cell. 30: 447-59. PMID 18450493 DOI: 10.1016/J.Molcel.2008.03.018  0.803
2008 Bialik S, Kimchi A. Autophagy and tumor suppression: recent advances in understanding the link between autophagic cell death pathways and tumor development. Advances in Experimental Medicine and Biology. 615: 177-200. PMID 18437896 DOI: 10.1007/978-1-4020-6554-5_9  0.447
2008 Bialik S, Berissi H, Kimchi A. A high throughput proteomics screen identifies novel substrates of death-associated protein kinase. Molecular & Cellular Proteomics : McP. 7: 1089-98. PMID 18283219 DOI: 10.1074/Mcp.M700579-Mcp200  0.481
2008 Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS, Baba M, Baehrecke EH, Bahr BA, Ballabio A, Bamber BA, Bassham DC, Bergamini E, Bi X, Biard-Piechaczyk M, ... ... Kimchi A, et al. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy. 4: 151-75. PMID 18188003 DOI: 10.4161/Auto.5338  0.332
2007 Shoval Y, Pietrokovski S, Kimchi A. ZIPK: a unique case of murine-specific divergence of a conserved vertebrate gene. Plos Genetics. 3: 1884-93. PMID 17953487 DOI: 10.1371/Journal.Pgen.0030180  0.798
2007 Maiuri MC, Zalckvar E, Kimchi A, Kroemer G. Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nature Reviews. Molecular Cell Biology. 8: 741-52. PMID 17717517 DOI: 10.1038/Nrm2239  0.753
2007 Eisenberg-Lerner A, Kimchi A. DAP kinase regulates JNK signaling by binding and activating protein kinase D under oxidative stress. Cell Death and Differentiation. 14: 1908-15. PMID 17703233 DOI: 10.1038/Sj.Cdd.4402212  0.784
2007 Kimchi A. Programmed cell death: from novel gene discovery to studies on network connectivity and emerging biomedical implications. Cytokine & Growth Factor Reviews. 18: 435-40. PMID 17702638 DOI: 10.1016/J.Cytogfr.2007.06.004  0.48
2007 Reef S, Shifman O, Oren M, Kimchi A. The autophagic inducer smARF interacts with and is stabilized by the mitochondrial p32 protein. Oncogene. 26: 6677-83. PMID 17486078 DOI: 10.1038/Sj.Onc.1210485  0.706
2007 Gozuacik D, Kimchi A. Autophagy and cell death. Current Topics in Developmental Biology. 78: 217-45. PMID 17338918 DOI: 10.1016/S0070-2153(06)78006-1  0.516
2006 Gozuacik D, Kimchi A. DAPk protein family and cancer. Autophagy. 2: 74-9. PMID 17139808 DOI: 10.4161/Auto.2.2.2459  0.506
2006 Reef S, Kimchi A. A smARF way to die: a novel short isoform of p19ARF is linked to autophagic cell death. Autophagy. 2: 328-30. PMID 16874094 DOI: 10.4161/Auto.3107  0.725
2006 Bialik S, Kimchi A. The death-associated protein kinases: structure, function, and beyond. Annual Review of Biochemistry. 75: 189-210. PMID 16756490 DOI: 10.1146/Annurev.Biochem.75.103004.142615  0.508
2006 Reef S, Zalckvar E, Shifman O, Bialik S, Sabanay H, Oren M, Kimchi A. A short mitochondrial form of p19ARF induces autophagy and caspase-independent cell death. Molecular Cell. 22: 463-75. PMID 16713577 DOI: 10.1016/J.Molcel.2006.04.014  0.819
2006 Citri A, Harari D, Shohat G, Ramakrishnan P, Gan J, Lavi S, Eisenstein M, Kimchi A, Wallach D, Pietrokovski S, Yarden Y. Hsp90 recognizes a common surface on client kinases. The Journal of Biological Chemistry. 281: 14361-9. PMID 16551624 DOI: 10.1074/Jbc.M512613200  0.432
2005 Marash L, Kimchi A. DAP5 and IRES-mediated translation during programmed cell death. Cell Death and Differentiation. 12: 554-62. PMID 15818401 DOI: 10.1038/Sj.Cdd.4401609  0.838
2005 Llambi F, Lourenço FC, Gozuacik D, Guix C, Pays L, Del Rio G, Kimchi A, Mehlen P. The dependence receptor UNC5H2 mediates apoptosis through DAP-kinase. The Embo Journal. 24: 1192-201. PMID 15729359 DOI: 10.1038/Sj.Emboj.7600584  0.471
2004 Shani G, Marash L, Gozuacik D, Bialik S, Teitelbaum L, Shohat G, Kimchi A. Death-associated protein kinase phosphorylates ZIP kinase, forming a unique kinase hierarchy to activate its cell death functions. Molecular and Cellular Biology. 24: 8611-26. PMID 15367680 DOI: 10.1128/Mcb.24.19.8611-8626.2004  0.813
2004 Bialik S, Kimchi A. DAP-kinase as a target for drug design in cancer and diseases associated with accelerated cell death. Seminars in Cancer Biology. 14: 283-94. PMID 15219621 DOI: 10.1016/J.Semcancer.2004.04.008  0.487
2004 Mukamel Z, Kimchi A. Death-associated protein 3 localizes to the mitochondria and is involved in the process of mitochondrial fragmentation during cell death. The Journal of Biological Chemistry. 279: 36732-8. PMID 15175341 DOI: 10.1074/Jbc.M400041200  0.474
2004 Lévy D, Plu-Bureau G, Decroix Y, Hugol D, Rostène W, Kimchi A, Gompel A. Death-associated protein kinase loss of expression is a new marker for breast cancer prognosis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 3124-30. PMID 15131053 DOI: 10.1158/1078-0432.Ccr-03-0213  0.431
2004 Gozuacik D, Kimchi A. Autophagy as a cell death and tumor suppressor mechanism. Oncogene. 23: 2891-906. PMID 15077152 DOI: 10.1038/Sj.Onc.1207521  0.543
2004 Bialik B, Bresnick AR, Kimchi A. DAP-kinase-mediated morphological changes are localization dependent and involve myosin-II phosphorylation Cell Death and Differentiation. 11: 631-644. PMID 15002035 DOI: 10.1038/Sj.Cdd.4401386  0.411
2002 Shohat G, Spivak-Kroizman T, Eisenstein M, Kimchi A. The regulation of death-associated protein (DAP) kinase in apoptosis. European Cytokine Network. 13: 398-400. PMID 12517721  0.426
2002 Shohat G, Shani G, Eisenstein M, Kimchi A. The DAP-kinase family of proteins: study of a novel group of calcium-regulated death-promoting kinases. Biochimica Et Biophysica Acta. 1600: 45-50. PMID 12445458 DOI: 10.1016/S1570-9639(02)00443-0  0.479
2002 Schori H, Yoles E, Wheeler LA, Raveh T, Kimchi A, Schwartz M. Immune-related mechanisms participating in resistance and susceptibility to glutamate toxicity. The European Journal of Neuroscience. 16: 557-64. PMID 12270031 DOI: 10.1046/J.1460-9568.2002.02134.X  0.697
2002 Inbal B, Bialik S, Sabanay I, Shani G, Kimchi A. DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death. The Journal of Cell Biology. 157: 455-68. PMID 11980920 DOI: 10.1083/Jcb.200109094  0.563
2002 Henis-Korenblit S, Shani G, Sines T, Marash L, Shohat G, Kimchi A. The caspase-cleaved DAP5 protein supports internal ribosome entry site-mediated translation of death proteins. Proceedings of the National Academy of Sciences of the United States of America. 99: 5400-5. PMID 11943866 DOI: 10.1073/Pnas.082102499  0.823
2002 Pelled D, Raveh T, Riebeling C, Fridkin M, Berissi H, Futerman AH, Kimchi A. Death-associated protein (DAP) kinase plays a central role in ceramide-induced apoptosis in cultured hippocampal neurons. The Journal of Biological Chemistry. 277: 1957-61. PMID 11709549 DOI: 10.1074/Jbc.M104677200  0.777
2002 Zueva ES, Chevkina EM, Kimchi A, Tatosyan AG. Suppression of the metastatic potential of v-src-transformed cells by the exogenous DAP kinase gene Molecular Biology. 36: 370-375. DOI: 10.1023/A:1016007329183  0.307
2001 Shohat G, Spivak-Kroizman T, Cohen O, Bialik S, Shani G, Berrisi H, Eisenstein M, Kimchi A. The Pro-apoptotic Function of Death-associated Protein Kinase Is Controlled by a Unique Inhibitory Autophosphorylation-based Mechanism Journal of Biological Chemistry. 276: 47460-47467. PMID 11579085 DOI: 10.1074/Jbc.M105133200  0.551
2001 Kimchi A. A cell death-promoting kinase Nature Structural Biology. 8: 824-826. PMID 11573080 DOI: 10.1038/Nsb1001-824  0.496
2001 Ma X, Karra S, Lindner DJ, Hu J, Reddy SPM, Kimchi A, Yodoi J, Kalvakolanu DD. Thioredoxin participates in a cell death pathway induced by interferon and retinoid combination Oncogene. 20: 3703-3715. PMID 11439333 DOI: 10.1038/Sj.Onc.1204477  0.49
2001 Cohen O, Kimchi A. DAP-kinase: From functional gene cloning to establishment of its role in apoptosis and cancer Cell Death and Differentiation. 8: 6-15. PMID 11313698 DOI: 10.1038/Sj.Cdd.4400794  0.518
2001 Raveh T, Kimchi A. DAP kinase-a proapoptotic gene that functions as a tumor suppressor. Experimental Cell Research. 264: 185-92. PMID 11237533 DOI: 10.1006/Excr.2000.5134  0.768
2001 Shani G, Henis-Korenblit S, Jona G, Gileadi O, Eisenstein M, Ziv T, Admon A, Kimchi A. Autophosphorylation restrains the apoptotic activity of DRP-1 kinase by controlling dimerization and calmodulin binding. The Embo Journal. 20: 1099-113. PMID 11230133 DOI: 10.1093/Emboj/20.5.1099  0.787
2001 Raveh T, Droguett G, Horwitz MS, DePinho RA, Kimchi A. DAP kinase activates a p19ARF/p53-mediated apoptotic checkpoint to suppress oncogenic transformation. Nature Cell Biology. 3: 1-7. PMID 11146619 DOI: 10.1038/35050500  0.775
2001 Wittke I, Mädge B, Wiedemeyer R, Kimchi A, Schwab M. DAP-5 is involved in MycN/IFNγ-induced apoptosis in human neuroblastoma cells Cancer Letters. 162: 237-243. PMID 11146231 DOI: 10.1016/S0304-3835(00)00644-3  0.533
2000 Raveh T, Berissi H, Eisenstein M, Spivak T, Kimchi A. A functional genetic screen identifies regions at the C-terminal tail and death-domain of death-associated protein kinase that are critical for its proapoptotic activity. Proceedings of the National Academy of Sciences of the United States of America. 97: 1572-7. PMID 10677501 DOI: 10.1073/Pnas.020519497  0.802
2000 Inbal B, Shani G, Cohen O, Kissil JL, Kimchi A. Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis Molecular and Cellular Biology. 20: 1044-1054. PMID 10629061 DOI: 10.1128/Mcb.20.3.1044-1054.2000  0.517
2000 Henis-Korenblit S, Strumpf NL, Goldstaub D, Kimchi A. A novel form of DAP5 protein accumulates in apoptotic cells as a result of caspase cleavage and internal ribosome entry site-mediated translation. Molecular and Cellular Biology. 20: 496-506. PMID 10611228 DOI: 10.1128/Mcb.20.2.496-506.2000  0.814
1999 Kimchi A. DAP kinase and DAP-3: Novel positive mediators of apoptosis Annals of the Rheumatic Diseases. 58. PMID 10577968 DOI: 10.1136/Ard.58.2008.I14  0.449
1999 Yamamoto M, Takahashi H, Nakamura T, Hioki T, Nagayama S, Ooashi N, Sun X, Ishii T, Kudo Y, Nakajima-Iijima S, Kimchi A, Uchino S. Developmental changes in distribution of death-associated protein kinase mRNAs. Journal of Neuroscience Research. 58: 674-83. PMID 10561695 DOI: 10.1002/(Sici)1097-4547(19991201)58:5<674::Aid-Jnr8>3.0.Co;2-3  0.47
1999 Cohen O, Inbal B, Kissil JL, Raveh T, Berissi H, Spivak-Kroizaman T, Feinstein E, Kimchi A. DAP-kinase participates in TNF-alpha- and Fas-induced apoptosis and its function requires the death domain. The Journal of Cell Biology. 146: 141-8. PMID 10402466 DOI: 10.1083/Jcb.146.1.141  0.8
1999 Kissil JL, Cohen O, Raveh T, Kimchi A. Structure-function analysis of an evolutionary conserved protein, DAP3, which mediates TNF-alpha- and Fas-induced cell death. The Embo Journal. 18: 353-62. PMID 9889192 DOI: 10.1093/Emboj/18.2.353  0.796
1998 Levy-Strumpf N, Kimchi A. Death associated proteins (DAPs): From gene identification to the analysis of their apoptotic and tumor suppressive functions Oncogene. 17: 3331-3340. PMID 9916995 DOI: 10.1038/Sj.Onc.1202588  0.566
1998 Kissil JL, Kimchi A. Death-associated proteins: from gene identification to the analysis of their apoptotic and tumour suppressive functions. Molecular Medicine Today. 4: 268-74. PMID 9679246 DOI: 10.1016/S1357-4310(98)01263-5  0.469
1997 Inbal B, Cohen O, Polak-Charcon S, Kopolovic J, Vadai E, Eisenbach L, Kimchi A. DAP kinase links the control of apoptosis to metastasis Nature. 390: 180-184. PMID 9367156 DOI: 10.1038/36599  0.45
1997 Kissil JL, Feinstein E, Cohen O, Jones PA, Tsai YC, Knowles MA, Eydmann ME, Kimchi A. DAP-kinase loss of expression in various carcinoma and B-cell lymphoma cell lines: possible implications for role as tumor suppressor gene. Oncogene. 15: 403-7. PMID 9242376 DOI: 10.1038/Sj.Onc.1201172  0.443
1997 Cohen O, Feinstein E, Kimchi A. DAP-kinase is a Ca2+/calmodulin-dependent, cytoskeletal-associated protein kinase, with cell death-inducing functions that depend on its catalytic activity Embo Journal. 16: 998-1008. PMID 9118961 DOI: 10.1093/Emboj/16.5.998  0.534
1997 Levy-Strumpf N, Deiss LP, Berissi H, Kimchi A. DAP-5, a novel homolog of eukaryotic translation initiation factor 4G isolated as a putative modulator of gamma interferon-induced programmed cell death Molecular and Cellular Biology. 17: 1615-1625. PMID 9032289 DOI: 10.1128/Mcb.17.3.1615  0.381
1996 Raveh T, Hovanessian AG, Meurs EF, Sonenberg N, Kimchi A. Double-stranded RNA-dependent protein kinase mediates c-Myc suppression induced by type I interferons. The Journal of Biological Chemistry. 271: 25479-84. PMID 8810318 DOI: 10.1074/Jbc.271.41.25479  0.759
1996 Tiefenbrun N, Melamed D, Levy N, Resnitzky D, Hoffmann I, Reed SI, Kimchi A. Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest Molecular and Cellular Biology. 16: 3934-3944. PMID 8668211 DOI: 10.1128/Mcb.16.7.3934  0.342
1996 Deiss LP, Galinka H, Berissi H, Cohen O, Kimchi A. Cathepsin D protease mediates programmed cell death induced by interferon-gamma, Fas/APO-1 and TNF-alpha. The Embo Journal. 15: 3861-3870. DOI: 10.1002/J.1460-2075.1996.Tb00760.X  0.475
1996 Deiss LP, Galinka H, Berissi H, Cohen O, Kimchi A. Cathepsin D protease mediates programmed cell death induced by interferon-γ, Fas/APO-1 and TNF-α Embo Journal. 15: 3861-3870.  0.374
1995 Feinstein E, Druck T, Kastury K, Berissi H, Goodart SA, Overhauser J, Kimchi A, Huebner K. Assignment of DAP1 and DAPK-Genes That Positively Mediate Programmed Cell Death Triggered by IFN-γ-to Chromosome Regions 5p12.2 and 9q34.1, Respectively Genomics. 29: 305-307. PMID 8530096 DOI: 10.1006/Geno.1995.1255  0.473
1995 Deiss LP, Feinstein E, Berissi H, Cohen O, Kimchi A. Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the γ interferon-induced cell death Genes and Development. 9: 15-30. PMID 7828849 DOI: 10.1101/Gad.9.1.15  0.518
1995 Kissil JL, Deiss LP, Bayewitch M, Raveh T, Khaspekov G, Kimchi A. Isolation of DAP3, a novel mediator of interferon-gamma-induced cell death. The Journal of Biological Chemistry. 270: 27932-6. PMID 7499268 DOI: 10.1074/Jbc.270.46.27932  0.776
1995 Feinstein E, Kimchi A, Wallach D, Boldin M, Varfolomeev E. The death domain: a module shared by proteins with diverse cellular functions Trends in Biochemical Sciences. 20: 342-344. PMID 7482697 DOI: 10.1016/S0968-0004(00)89070-2  0.413
1993 Yonish-Rouach E, Grunwald D, Wilder S, Kimchi A, May E, Lawrence JJ, May P, Oren M. p53-mediated cell death: relationship to cell cycle control. Molecular and Cellular Biology. 13: 1415-23. PMID 8441387 DOI: 10.1128/Mcb.13.3.1415  0.481
1993 Zafriri D, Argaman M, Canaani E, Kimchi A. Induction of protein-tyrosine-phosphatase activity by interleukin 6 in M1 myeloblastic cells and analysis of possible counteractions by the BCR-ABL oncogene Proceedings of the National Academy of Sciences of the United States of America. 90: 477-481. PMID 8421678 DOI: 10.1073/Pnas.90.2.477  0.41
1993 Levy N, Yonish-Rouach E, Oren M, Kimchi A. Complementation by wild-type p53 of interleukin-6 effects on M1 cells: Induction of cell cycle exit and cooperativity with c-myc suppression Molecular and Cellular Biology. 13: 7942-7952. PMID 8247009 DOI: 10.1128/Mcb.13.12.7942  0.391
1993 Melamed D, Tiefenbrun N, Yarden A, Kimchi A. Interferons and interleukin-6 suppress the DNA-binding activity of E2F in growth-sensitive hematopoietic cells Molecular and Cellular Biology. 13: 5255-5265. PMID 7689148 DOI: 10.1128/Mcb.13.9.5255  0.39
1992 Kimchi A. Cytokine triggered molecular pathways that control cell cycle arrest Journal of Cellular Biochemistry. 50: 1-9. PMID 1385455 DOI: 10.1002/Jcb.240500102  0.348
1992 Resnitzky D, Tiefenbrun N, Berissi H, Kimchi A. Interferons and interleukin 6 suppress phosphorylation of the retinoblastoma protein in growth-sensitive hematopoietic cells Proceedings of the National Academy of Sciences of the United States of America. 89: 402-406. PMID 1370354 DOI: 10.1073/Pnas.89.1.402  0.403
1991 Yonish-Rouach E, Kimchi A, Rubinstein M. The antiproliferative effect of cyclosporine on hematopoietic and lymphoblastoid cell lines — Common mechanistic elements with interferon-alpha Transplantation. 51: 1276-1282. PMID 2048200 DOI: 10.1097/00007890-199106000-00025  0.349
1991 Yonish-Rouach E, Resnftzky D, Lotem J, Sachs L, Kimchi A, Oren M. Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6 Nature. 352: 345-347. PMID 1852210 DOI: 10.1038/352345A0  0.407
1991 Tiefenbrun N, Kimchi A. The involvement of protein kinase C in mediating growth suppressive signals of interferons in hematopoietic cells Oncogene. 6: 1001-1007. PMID 1712443  0.318
1988 Kimchi A, Resnitzky D, Ber R, Gat G. Recessive genetic deregulation abrogates c-myc suppression by interferon and is implicated in oncogenesis Molecular and Cellular Biology. 8: 2828-2836. PMID 3043196 DOI: 10.1128/Mcb.8.7.2828  0.352
1988 Kimchi A, Wang XF, Weinberg RA, Cheifetz S, Massagué J. Absence of TGF-β receptors and growth inhibitory responses in retinoblastoma cells Science. 240: 196-199. PMID 2895499 DOI: 10.1126/Science.2895499  0.306
1987 Bendori R, Resnitzky D, Kimchi A. Changes in p53 mRNA expression during terminal differentiation of murine erythroleukemia cells Virology. 161: 607-611. PMID 3318097 DOI: 10.1016/0042-6822(87)90159-0  0.365
1986 Yarden A, Kimchi A. Tumor necrosis factor reduces c-myc expression and cooperates with interferon-γ in HeLa cells Science. 234: 1419-1421. PMID 3097823 DOI: 10.1126/Science.3097823  0.339
1986 Resnitzky D, Yarden A, Zipori D, Kimchi A. Autocrine β-related interferon controls c-myc suppression and growth arrest during hematopoietic cell differentiation Cell. 46: 31-40. PMID 2941150 DOI: 10.1016/0092-8674(86)90857-3  0.357
1985 Einat M, Resnitzky D, Kimchi A. Close link between reduction of c-myc expression by interferon and G 0/G1 arrest Nature. 313: 597-600. PMID 3881681 DOI: 10.1038/313597A0  0.376
1985 Einat M, Resnitzky D, Kimchi A. Inhibitory effects of interferon on the expression of genes regulated by platelet-derived growth factor Proceedings of the National Academy of Sciences of the United States of America. 82: 7608-7612. PMID 2415966 DOI: 10.1073/Pnas.82.22.7608  0.334
1984 Yarden A, Shure-Gottlieb H, Chebath J, Revel M, Kimchi A. Autogenous production of interferon-beta switches on HLA genes during differentiation of histiocytic lymphoma U937 cells Embo Journal. 3: 969-973. PMID 6376119 DOI: 10.1002/J.1460-2075.1984.Tb01915.X  0.308
1983 -Dori RB, Resnitzki D, Kimchi A. Reduction in p53 synthesis during differentiation of Friend-erythroleukemia cells. Correlation with the commitment to terminal cell division Febs Letters. 162: 384-389. PMID 6354748 DOI: 10.1016/0014-5793(83)80792-3  0.363
1982 Friedman Einat M, Revel M, Kimchi A. Initial characterization of a spontaneous interferon secreted during growth and differentiation of Friend erythroleukemia cells Molecular and Cellular Biology. 2: 1472-1480. DOI: 10.1128/Mcb.2.12.1472  0.318
1981 Revel M, Wallach D, Merlin G, Schattner A, Schmidt A, Wolf D, Shulman L, Kimchi A. [20] Interferon-induced enzymes: Microassays and their applications; purification and assay of (2′-5′)-oligoadenylate synthetase and assay of 2′-phosphodiesterase Methods in Enzymology. 79: 149-161. PMID 6173659 DOI: 10.1016/S0076-6879(81)79024-4  0.349
1981 Kimchi A, Shure H, Lapidot Y, Rapoport S, Panet A, Revel M. Antimitogenic effects of interferon and (2′-5′)-oligoadenylate in synchronized 3T3 fibroblasts Febs Letters. 134: 212-216. PMID 6171460 DOI: 10.1016/0014-5793(81)80604-7  0.36
1981 KIMCHI A, SHURE H, REVEL M. Anti‐mitogenic Function of Interferon‐Induced (2′‐5′)Oligo(adenylate) and Growth‐Related Variations in Enzymes that Synthesize and Degrade This Oligonucleotide European Journal of Biochemistry. 114: 5-10. PMID 6163628 DOI: 10.1111/J.1432-1033.1981.Tb06163.X  0.35
1979 Kimchi A, Shure H, Revel M. Regulation of lymphocyte mitogenesis by (2'-5') oligo-isoadenylate [22] Nature. 282: 849-851. PMID 514363 DOI: 10.1038/282849A0  0.344
1979 Chernajovsky Y, Kimchi A, Schmidt A, Zilberstein A, Revel M. Differential effects of two interferon-induced translational inhibitors on initiation of protein synthesis. European Journal of Biochemistry. 96: 35-41. PMID 456366 DOI: 10.1111/J.1432-1033.1979.Tb13010.X  0.438
1979 Zilberstein A, Kimchi A, Schmidt A, Revel M. Isolation of two interferon-induced translational inhibitors: a protein kinase and an oligo-isoadenylate synthetase. Proceedings of the National Academy of Sciences of the United States of America. 75: 4734-8. PMID 283387 DOI: 10.1073/Pnas.75.10.4734  0.443
1979 Kimchi A, Shulman L, Schmidt A, Chernajovsky Y, Fradin A, Revel M. Kinetics of the induction of three translation-regulatory enzymes by interferon Proceedings of the National Academy of Sciences of the United States of America. 76: 3208-3212. PMID 226962 DOI: 10.1073/Pnas.76.7.3208  0.367
1979 Kimchi A, Zilberstein A, Schmidt A, Shulman L, Revel M. The interferon-induced protein kinase PK-i from mouse L cells Journal of Biological Chemistry. 254: 9846-9853. PMID 226529  0.328
1978 Revel M, Gilboa E, Kimchi A, Schmidt A, Shulman L, Yakobson E, Zilberstein A. Interferon-induced translational regulation. Texas Reports On Biology and Medicine. 35: 47-58. DOI: 10.1016/B978-0-08-022624-8.50011-9  0.425
Show low-probability matches.