| Year |
Citation |
Score |
| 2024 |
Aisen P, Bateman RJ, Crowther D, Cummings J, Dwyer J, Iwatsubo T, Kosco-Vilbois M, McDade E, Mohs R, Scheltens P, Sperling R, Selkoe D. The case for regulatory approval of amyloid-lowering immunotherapies in Alzheimer's disease based on clearcut biomarker evidence. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 39535341 DOI: 10.1002/alz.14342 |
0.357 |
|
| 2024 |
Gunasekaran TI, Meena D, Lee AJ, Wu S, Dumitrescu L, Sperling R, Hohman TJ, Huang J, Dehghan A, Tzoulaki I, Mayeux R, Vardarajan B. Genome-wide scan of Flortaucipir PET levels finds associated with cerebral tau deposition. Medrxiv : the Preprint Server For Health Sciences. PMID 39417126 DOI: 10.1101/2024.10.04.24314853 |
0.344 |
|
| 2024 |
Lam AD, Thibault EG, Mayblyum DV, Hsieh S, Pellerin KR, Sternberg EJ, Viswanathan A, Buss S, Sarkis RA, Jacobs HIL, Johnson KA, Sperling RA. Association of Seizure Foci and Location of Tau and Amyloid Deposition and Brain Atrophy in Patients With Alzheimer Disease and Seizures. Neurology. 103: e209920. PMID 39331846 DOI: 10.1212/WNL.0000000000209920 |
0.333 |
|
| 2024 |
Nho K, Risacher SL, Apostolova LG, Bice PJ, Brosch JR, Deardorff R, Faber K, Farlow MR, Foroud T, Gao S, Rosewood T, Kim JP, Nudelman K, Yu M, Aisen P, ... Sperling R, et al. CYP1B1-RMDN2 Alzheimer's disease endophenotype locus identified for cerebral tau PET. Nature Communications. 15: 8251. PMID 39304655 DOI: 10.1038/s41467-024-52298-2 |
0.528 |
|
| 2024 |
Stankeviciute L, Chhatwal JP, Levin R, Pinilla V, Schultz AP, Redline S, Johnson KA, Sperling RA, Kozhemiako N, Purcell S, Djonlagic I. Amyloid beta-independent sleep markers associated with early regional tau burden and cortical thinning. Alzheimer's & Dementia (Amsterdam, Netherlands). 16: e12616. PMID 39077684 DOI: 10.1002/dad2.12616 |
0.305 |
|
| 2024 |
Schultz SA, Liu L, Schultz AP, Fitzpatrick CD, Levin R, Bellier JP, Shirzadi Z, Joseph-Mathurin N, Chen CD, Benzinger TLS, Day GS, Farlow MR, Gordon BA, Hassenstab JJ, Jack CR, ... ... Sperling RA, et al. γ-Secretase activity, clinical features, and biomarkers of autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analysis of the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS). The Lancet. Neurology. PMID 39074479 DOI: 10.1016/S1474-4422(24)00236-9 |
0.527 |
|
| 2024 |
Engels-Domínguez N, Riphagen JM, Van Egroo M, Koops EA, Smegal LF, Becker JA, Prokopiou PC, Bueichekú E, Kwong KK, Rentz DM, Salat DH, Sperling RA, Johnson KA, Jacobs HIL. Lower Locus Coeruleus Integrity Signals Elevated Entorhinal Tau and Clinical Progression in Asymptomatic Older Individuals. Annals of Neurology. PMID 39007398 DOI: 10.1002/ana.27022 |
0.81 |
|
| 2024 |
Farrell ME, Thibault EG, Becker JA, Price JC, Healy BC, Hanseeuw BJ, Buckley RF, Jacobs HIL, Schultz AP, Chen CD, Sperling RA, Johnson KA. Spatial extent as a sensitive amyloid-PET metric in preclinical Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38988055 DOI: 10.1002/alz.14036 |
0.656 |
|
| 2024 |
Boyle R, Townsend DL, Klinger HM, Scanlon CE, Yuan Z, Coughlan GT, Seto M, Shirzadi Z, Yau WW, Jutten RJ, Schneider C, Farrell ME, Hanseeuw BJ, Mormino EC, Yang HS, ... ... Sperling RA, et al. Identifying longitudinal cognitive resilience from cross-sectional amyloid, tau, and neurodegeneration. Alzheimer's Research & Therapy. 16: 148. PMID 38961512 DOI: 10.1186/s13195-024-01510-y |
0.664 |
|
| 2024 |
Jack CR, Andrews JS, Beach TG, Buracchio T, Dunn B, Graf A, Hansson O, Ho C, Jagust W, McDade E, Molinuevo JL, Okonkwo OC, Pani L, Rafii MS, Scheltens P, ... ... Sperling R, et al. Revised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association Workgroup. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38934362 DOI: 10.1002/alz.13859 |
0.378 |
|
| 2024 |
Dubbelman MA, Diez I, Gonzalez C, Amariglio RE, Becker JA, Chhatwal JP, Gatchel JR, Johnson KA, Locascio JJ, Udeogu OJ, Wang S, Papp KV, Properzi MJ, Rentz DM, Schultz AP, ... Sperling RA, et al. Amyloid and tau burden relate to longitudinal changes in the performance of complex everyday activities among cognitively unimpaired older adults: results from the performance-based Harvard Automated Phone Task. Frontiers in Aging Neuroscience. 16: 1420290. PMID 38934017 DOI: 10.3389/fnagi.2024.1420290 |
0.331 |
|
| 2024 |
Quiroz YT, Aguillon D, Aguirre-Acevedo DC, Vasquez D, Zuluaga Y, Baena AY, Madrigal L, Hincapié L, Sanchez JS, Langella S, Posada-Duque R, Littau JL, Villalba-Moreno ND, Vila-Castelar C, Ramirez Gomez L, ... ... Sperling RA, et al. Christchurch Heterozygosity and Autosomal Dominant Alzheimer's Disease. The New England Journal of Medicine. 390: 2156-2164. PMID 38899694 DOI: 10.1056/NEJMoa2308583 |
0.345 |
|
| 2024 |
Engels-Domínguez N, Koops EA, Hsieh S, Wiklund EE, Schultz AP, Riphagen JM, Prokopiou PC, Hanseeuw BJ, Rentz DM, Sperling RA, Johnson KA, Jacobs HIL. Lower in vivo locus coeruleus integrity is associated with lower cortical thickness in older individuals with elevated Alzheimer's pathology: a cohort study. Alzheimer's Research & Therapy. 16: 129. PMID 38886798 DOI: 10.1186/s13195-024-01500-0 |
0.833 |
|
| 2024 |
Seto M, Hohman TJ, Mormino EC, Papp KV, Amariglio RE, Rentz DM, Johnson KA, Schultz AP, Sperling RA, Buckley RF, Yang HS. Parental History of Memory Impairment and β-Amyloid in Cognitively Unimpaired Older Adults. Jama Neurology. PMID 38884955 DOI: 10.1001/jamaneurol.2024.1763 |
0.336 |
|
| 2024 |
Diez I, Ortiz-Terán L, Ng TSC, Albers MW, Marshall G, Orwig W, Kim CM, Bueichekú E, Montal V, Olofsson J, Vannini P, El Fahkri G, Sperling R, Johnson K, Jacobs HIL, et al. Tau propagation in the brain olfactory circuits is associated with smell perception changes in aging. Nature Communications. 15: 4809. PMID 38844444 DOI: 10.1038/s41467-024-48462-3 |
0.602 |
|
| 2024 |
Pahl J, Prokopiou PC, Bueichekú E, Schultz AP, Papp KV, Farrell ME, Rentz DM, Sperling RA, Johnson KA, Jacobs HIL. Locus coeruleus integrity and left frontoparietal connectivity provide resilience against attentional decline in preclinical alzheimer's disease. Alzheimer's Research & Therapy. 16: 119. PMID 38822365 DOI: 10.1186/s13195-024-01485-w |
0.662 |
|
| 2024 |
Jadick MF, Robinson T, Farrell ME, Klinger H, Buckley RF, Marshall GA, Vannini P, Rentz DM, Johnson KA, Sperling RA, Amariglio RE. Associations Between Self and Study Partner Report of Cognitive Decline With Regional Tau in a Multicohort Study. Neurology. 102: e209447. PMID 38810211 DOI: 10.1212/WNL.0000000000209447 |
0.339 |
|
| 2024 |
Lee S, Zide BS, Palm ST, Drew WJ, Sperling RA, Jacobs HIL, Siddiqi SH, Donovan NJ. Specific Association of Worry With Amyloid-β But Not Tau in Cognitively Unimpaired Older Adults. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. PMID 38763835 DOI: 10.1016/j.jagp.2024.04.016 |
0.626 |
|
| 2024 |
Honig LS, Sabbagh MN, van Dyck CH, Sperling RA, Hersch S, Matta A, Giorgi L, Gee M, Kanekiyo M, Li D, Purcell D, Dhadda S, Irizarry M, Kramer L. Updated safety results from phase 3 lecanemab study in early Alzheimer's disease. Alzheimer's Research & Therapy. 16: 105. PMID 38730496 DOI: 10.1186/s13195-024-01441-8 |
0.351 |
|
| 2024 |
Fortea J, Pegueroles J, Alcolea D, Belbin O, Dols-Icardo O, Vaqué-Alcázar L, Videla L, Gispert JD, Suárez-Calvet M, Johnson SC, Sperling R, Bejanin A, Lleó A, Montal V. APOE4 homozygozity represents a distinct genetic form of Alzheimer's disease. Nature Medicine. 30: 1284-1291. PMID 38710950 DOI: 10.1038/s41591-024-02931-w |
0.382 |
|
| 2024 |
Schneider C, Prokopiou PC, Papp KV, Engels-Domínguez N, Hsieh S, Juneau TA, Schultz AP, Rentz DM, Sperling RA, Johnson KA, Jacobs HIL. Atrophy links lower novelty-related locus coeruleus connectivity to cognitive decline in preclinical AD. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38676563 DOI: 10.1002/alz.13839 |
0.635 |
|
| 2024 |
Bueichekú E, Diez I, Kim CM, Becker JA, Koops EA, Kwong K, Papp KV, Salat DH, Bennett DA, Rentz DM, Sperling RA, Johnson KA, Sepulcre J, Jacobs HIL. Spatiotemporal patterns of locus coeruleus integrity predict cortical tau and cognition. Nature Aging. PMID 38664576 DOI: 10.1038/s43587-024-00626-y |
0.83 |
|
| 2024 |
Molina-Henry DP, Raman R, Liu A, Langford O, Johnson K, Shum LK, Glover CM, Dhadda S, Irizarry M, Jimenez-Maggiora G, Braunstein JB, Yarasheski K, Venkatesh V, West T, Verghese PB, ... ... Sperling RA, et al. Racial and ethnic differences in plasma biomarker eligibility for a preclinical Alzheimer's disease trial. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38629508 DOI: 10.1002/alz.13803 |
0.52 |
|
| 2024 |
Grill JD, Raman R, Ernstrom K, Wang S, Donohue MC, Aisen PS, Karlawish J, Henley D, Romano G, Novak G, Brashear HR, Sperling RA. Immediate Reactions to Alzheimer Biomarker Disclosure in Cognitively Unimpaired Individuals in a Global Truncated Randomized Trial. Neurology. Clinical Practice. 14: e200265. PMID 38585443 DOI: 10.1212/CPJ.0000000000200265 |
0.538 |
|
| 2024 |
Burling JE, Katz Z, Yuan Z, Munro C, Mimmack K, Ma G, Hanseeuw BJ, Papp KV, Amariglio RE, Vannini P, Rentz DM, Quiroz YT, Johnson KA, Sperling RA, Blacker D, et al. Study Partner Report of Apathy in Older Adults is Associated with AD Biomarkers: Findings from the Harvard Aging Brain Study. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. PMID 38443298 DOI: 10.1016/j.jagp.2024.01.020 |
0.321 |
|
| 2024 |
Therriault J, Schindler SE, Salvadó G, Pascoal TA, Benedet AL, Ashton NJ, Karikari TK, Apostolova L, Murray ME, Verberk I, Vogel JW, La Joie R, Gauthier S, Teunissen C, Rabinovici GD, ... ... Sperling R, et al. Biomarker-based staging of Alzheimer disease: rationale and clinical applications. Nature Reviews. Neurology. PMID 38429551 DOI: 10.1038/s41582-024-00942-2 |
0.34 |
|
| 2024 |
Yang HS, Yau WW, Carlyle BC, Trombetta BA, Zhang C, Shirzadi Z, Schultz AP, Pruzin JJ, Fitzpatrick CD, Kirn DR, Rabin JS, Buckley RF, Hohman TJ, Rentz DM, Tanzi RE, ... ... Sperling RA, et al. Plasma VEGFA and PGF impact longitudinal tau and cognition in preclinical Alzheimer's disease. Brain : a Journal of Neurology. PMID 38315899 DOI: 10.1093/brain/awae034 |
0.381 |
|
| 2023 |
Yang HS, Teng L, Kang D, Menon V, Ge T, Finucane HK, Schultz AP, Properzi M, Klein HU, Chibnik LB, Schneider JA, Bennett DA, Hohman TJ, Mayeux RP, Johnson KA, ... ... Sperling RA, et al. Cell-type-specific Alzheimer's disease polygenic risk scores are associated with distinct disease processes in Alzheimer's disease. Nature Communications. 14: 7659. PMID 38036535 DOI: 10.1038/s41467-023-43132-2 |
0.357 |
|
| 2023 |
Papp KV, Jutten RJ, Soberanes D, Weizenbaum E, Hsieh S, Molinare C, Buckley R, Betensky RA, Marshall GA, Johnson KA, Rentz DM, Sperling R, Amariglio RE. Early detection of amyloid-related changes in memory among cognitively unimpaired older adults with daily digital testing. Annals of Neurology. PMID 37991080 DOI: 10.1002/ana.26833 |
0.379 |
|
| 2023 |
Hanseeuw BJ, Jacobs HI, Schultz AP, Buckley RF, Farrell ME, Guehl NJ, Becker JA, Properzi M, Sanchez JS, Quiroz YT, Vannini P, Sepulcre J, Yang HS, Chhatwal JP, Gatchel J, ... ... Sperling RA, et al. Association of pathological and volumetric biomarker changes with cognitive decline in clinically normal adults: Harvard Aging Brain Study. Neurology. PMID 37968130 DOI: 10.1212/WNL.0000000000207962 |
0.696 |
|
| 2023 |
Rissman RA, Langford O, Raman R, Donohue MC, Abdel-Latif S, Meyer MR, Wente-Roth T, Kirmess KM, Ngolab J, Winston CN, Jimenez-Maggiora G, Rafii MS, Sachdev P, West T, Yarasheski KE, ... ... Sperling RA, et al. Plasma Aβ42/Aβ40 and phospho-tau217 concentration ratios increase the accuracy of amyloid PET classification in preclinical Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37932961 DOI: 10.1002/alz.13542 |
0.518 |
|
| 2023 |
Shirzadi Z, Schultz SA, Yau WW, Joseph-Mathurin N, Fitzpatrick CD, Levin R, Kantarci K, Preboske GM, Jack CR, Farlow MR, Hassenstab J, Jucker M, Morris JC, Xiong C, Karch CM, ... ... Sperling RA, et al. Etiology of White Matter Hyperintensities in Autosomal Dominant and Sporadic Alzheimer Disease. Jama Neurology. PMID 37843849 DOI: 10.1001/jamaneurol.2023.3618 |
0.329 |
|
| 2023 |
Grill JD, Flournoy C, Dhadda S, Ernstrom K, Sperling R, Henry DM, Tranotti K, Harris R, Kanekiyo M, Gee M, Irizarry M, Kramer L, Aisen P, Raman R. Eligibility rates among racially and ethnically diverse US participants in Phase 2 and Phase 3 placebo-controlled, double-blind, randomized trials of lecanemab and elenbecestat in early Alzheimer's disease. Annals of Neurology. PMID 37830926 DOI: 10.1002/ana.26819 |
0.49 |
|
| 2023 |
Scott MR, Edwards NC, Properzi MJ, Jacobs HI, Price JC, Lois C, Farrell ME, Hanseeuw BJ, Thibault EG, Rentz DM, Johnson KA, Sperling RA, Schultz AP, Buckley RF. Contribution of extracerebral tracer retention and partial volume effects to sex differences in Flortaucipir-PET signal. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X231196978. PMID 37728659 DOI: 10.1177/0271678X231196978 |
0.548 |
|
| 2023 |
Gagliardi G, Rodriguez-Vieitez E, Montal V, Sepulcre J, Diez I, Lois C, Hanseeuw B, Schultz AP, Properzi MJ, Papp KV, Marshall GA, Fortea J, Johnson KA, Sperling RA, Vannini P. Cortical microstructural changes predict tau accumulation and episodic memory decline in older adults harboring amyloid. Communications Medicine. 3: 106. PMID 37528163 DOI: 10.1038/s43856-023-00324-7 |
0.344 |
|
| 2023 |
Prokopiou PC, Engels-Domínguez N, Schultz AP, Sepulcre J, Koops EA, Papp KV, Marshall GA, Normandin MD, El Fakhri G, Rentz D, Sperling RA, Johnson KA, Jacobs HIL. Association of Novelty-Related Locus Coeruleus Function With Entorhinal Tau Deposition and Memory Decline in Preclinical Alzheimer Disease. Neurology. PMID 37491329 DOI: 10.1212/WNL.0000000000207646 |
0.827 |
|
| 2023 |
Sperling RA, Donohue MC, Raman R, Rafii MS, Johnson K, Masters CL, van Dyck CH, Iwatsubo T, Marshall GA, Yaari R, Mancini M, Holdridge KC, Case M, Sims JR, Aisen PS. Trial of Solanezumab in Preclinical Alzheimer's Disease. The New England Journal of Medicine. PMID 37458272 DOI: 10.1056/NEJMoa2305032 |
0.496 |
|
| 2023 |
Yang HS, Teng L, Kang D, Menon V, Ge T, Finucane HK, Schultz AP, Properzi M, Klein HU, Chibnik LB, Schneider JA, Bennett DA, Hohman TJ, Mayeux RP, Johnson KA, ... ... Sperling RA, et al. Cell-type-specific Alzheimer's disease polygenic risk scores are associated with distinct disease processes in Alzheimer's disease. Medrxiv : the Preprint Server For Health Sciences. PMID 37333223 DOI: 10.1101/2023.06.01.23290850 |
0.391 |
|
| 2023 |
Reynolds G, Buckley R, Papp K, Schultz SA, Rentz D, Sperling R, Amariglio R. Relation of modifiable lifestyle and mood factors to cognitive concerns among participants and their study partners in the A4 screen data. Alzheimer's & Dementia (Amsterdam, Netherlands). 15: e12435. PMID 37304049 DOI: 10.1002/dad2.12435 |
0.331 |
|
| 2023 |
Schultz SA, Shirzadi Z, Schultz AP, Liu L, Fitzpatrick CD, McDade E, Barthelemy NR, Renton A, Esposito B, Joseph-Mathurin N, Cruchaga C, Chen CD, Goate A, Allegri RF, Benzinger TLS, ... ... Sperling RA, et al. Location of pathogenic variants in PSEN1 impacts progression of cognitive, clinical, and neurodegenerative measures in autosomal-dominant Alzheimer's disease. Aging Cell. e13871. PMID 37291760 DOI: 10.1111/acel.13871 |
0.365 |
|
| 2023 |
Gonzalez C, Mimmack KJ, Amariglio RE, Becker JA, Chhatwal JP, Fitzpatrick CD, Gatchel JR, Johnson KA, Katz ZS, Kuppe MK, Locascio JJ, Udeogu OJ, Papp KV, Premnath P, Properzi MJ, ... ... Sperling RA, et al. Associations of the Harvard Automated Phone Task and Alzheimer's Disease Pathology in Cognitively Normal Older Adults: Preliminary Findings. Journal of Alzheimer's Disease : Jad. PMID 37212093 DOI: 10.3233/JAD-220885 |
0.404 |
|
| 2023 |
Kirn DR, Grill JD, Aisen P, Ernstrom K, Gale S, Heidebrink J, Jicha G, Jimenez-Maggiora G, Johnson L, Peskind E, McCann K, Shaffer E, Sultzer D, Wang S, Sperling R, et al. Centralizing prescreening data collection to inform data-driven approaches to clinical trial recruitment. Alzheimer's Research & Therapy. 15: 88. PMID 37131229 DOI: 10.1186/s13195-023-01235-4 |
0.359 |
|
| 2023 |
Van Egroo M, Riphagen JM, Ashton NJ, Janelidze S, Sperling RA, Johnson KA, Yang HS, Bennett DA, Blennow K, Hansson O, Zetterberg H, Jacobs HIL. Ultra-high field imaging, plasma markers and autopsy data uncover a specific rostral locus coeruleus vulnerability to hyperphosphorylated tau. Molecular Psychiatry. 1-11. PMID 37020050 DOI: 10.1038/s41380-023-02041-y |
0.611 |
|
| 2023 |
Nho K, Risacher SL, Apostolova L, Bice PJ, Brosch J, Deardorff R, Faber K, Farlow MR, Foroud T, Gao S, Rosewood T, Kim JP, Nudelman K, Yu M, Aisen P, ... Sperling R, et al. Novel Alzheimer's disease locus identified by genome-wide association analysis of cerebral tau deposition on PET. Medrxiv : the Preprint Server For Health Sciences. PMID 36993271 DOI: 10.1101/2023.02.27.23286048 |
0.53 |
|
| 2023 |
Young CB, Mormino EC, Poston KL, Johnson KA, Rentz DM, Sperling RA, Papp KV. Computerized cognitive practice effects in relation to amyloid and tau in preclinical Alzheimer's disease: Results from a multi-site cohort. Alzheimer's & Dementia (Amsterdam, Netherlands). 15: e12414. PMID 36950699 DOI: 10.1002/dad2.12414 |
0.369 |
|
| 2023 |
Winston CN, Langford O, Levin N, Raman R, Yarasheski K, West T, Abdel-Latif S, Donohue M, Nakamura A, Toba K, Masters CL, Doecke J, Sperling RA, Aisen PS, Rissman RA. Evaluation of Blood-Based Plasma Biomarkers as Potential Markers of Amyloid Burden in Preclinical Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 36710683 DOI: 10.3233/JAD-221118 |
0.483 |
|
| 2023 |
Young CB, Johns E, Kennedy G, Belloy ME, Insel PS, Greicius MD, Sperling RA, Johnson KA, Poston KL, Mormino EC. APOE effects on regional tau in preclinical Alzheimer's disease. Molecular Neurodegeneration. 18: 1. PMID 36597122 DOI: 10.1186/s13024-022-00590-4 |
0.314 |
|
| 2022 |
Aguillon D, Langella S, Chen Y, Sanchez JS, Su Y, Vila-Castelar C, Vasquez D, Zetterberg H, Hansson O, Dage JL, Janelidze S, Chen K, Fox-Fuller JT, Aduen P, Martinez JE, ... ... Sperling RA, et al. Plasma p-tau217 predicts in vivo brain pathology and cognition in autosomal dominant Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36571821 DOI: 10.1002/alz.12906 |
0.365 |
|
| 2022 |
Ossenkoppele R, Pichet Binette A, Groot C, Smith R, Strandberg O, Palmqvist S, Stomrud E, Tideman P, Ohlsson T, Jögi J, Johnson K, Sperling R, Dore V, Masters CL, Rowe C, et al. Amyloid and tau PET-positive cognitively unimpaired individuals are at high risk for future cognitive decline. Nature Medicine. 28: 2381-2387. PMID 36357681 DOI: 10.1038/s41591-022-02049-x |
0.321 |
|
| 2022 |
Rafii MS, Sperling RA, Donohue MC, Zhou J, Roberts C, Irizarry MC, Dhadda S, Sethuraman G, Kramer LD, Swanson CJ, Li D, Krause S, Rissman RA, Walter S, Raman R, et al. The AHEAD 3-45 Study: Design of a prevention trial for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35971310 DOI: 10.1002/alz.12748 |
0.548 |
|
| 2022 |
Insel PS, Young CB, Aisen PS, Johnson KA, Sperling RA, Mormino EC, Donohue MC. Tau positron emission tomography in preclinical Alzheimer's disease. Brain : a Journal of Neurology. PMID 35962782 DOI: 10.1093/brain/awac299 |
0.555 |
|
| 2022 |
Hansson O, Edelmayer RM, Boxer AL, Carrillo MC, Mielke MM, Rabinovici GD, Salloway S, Sperling R, Zetterberg H, Teunissen CE. The Alzheimer's Association appropriate use recommendations for blood biomarkers in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35908251 DOI: 10.1002/alz.12756 |
0.367 |
|
| 2022 |
Strikwerda-Brown C, Hobbs DA, Gonneaud J, St-Onge F, Binette AP, Ozlen H, Provost K, Soucy JP, Buckley RF, Benzinger TLS, Morris JC, Villemagne VL, Doré V, Sperling RA, Johnson KA, et al. Association of Elevated Amyloid and Tau Positron Emission Tomography Signal With Near-Term Development of Alzheimer Disease Symptoms in Older Adults Without Cognitive Impairment. Jama Neurology. PMID 35907254 DOI: 10.1001/jamaneurol.2022.2379 |
0.418 |
|
| 2022 |
Yau WW, Shirzadi Z, Yang HS, Ikoba AP, Rabin JS, Properzi MJ, Kirn DR, Schultz AP, Rentz DM, Johnson KA, Sperling RA, Chhatwal JP. Tau mediates synergistic influence of vascular risk and Aβ on cognitive decline. Annals of Neurology. PMID 35880989 DOI: 10.1002/ana.26460 |
0.361 |
|
| 2022 |
Baradaran H, Peloso GM, Polak JF, Killiany RJ, Ghosh S, DeCarli CS, Thibault EG, Sperling RA, Johnson KA, Beiser A, Romero JR, Seshadri S. Association of Carotid Intima Media Thickening with Future Brain Region Specific Amyloid-β Burden. Journal of Alzheimer's Disease : Jad. PMID 35871328 DOI: 10.3233/JAD-215679 |
0.319 |
|
| 2022 |
Sepulveda-Falla D, Sanchez JS, Almeida MC, Boassa D, Acosta-Uribe J, Vila-Castelar C, Ramirez-Gomez L, Baena A, Aguillon D, Villalba-Moreno ND, Littau JL, Villegas A, Beach TG, White CL, Ellisman M, ... ... Sperling RA, et al. Distinct tau neuropathology and cellular profiles of an APOE3 Christchurch homozygote protected against autosomal dominant Alzheimer's dementia. Acta Neuropathologica. PMID 35838824 DOI: 10.1007/s00401-022-02467-8 |
0.345 |
|
| 2022 |
Buckley RF, O'Donnell A, McGrath ER, Jacobs HIL, Lois C, Satizabal CL, Ghosh S, Rubinstein ZB, Murabito JM, Sperling RA, Johnson KA, Seshadri S, Beiser AS. Menopause status moderates sex differences in tau burden: a Framingham PET Study. Annals of Neurology. PMID 35471588 DOI: 10.1002/ana.26382 |
0.58 |
|
| 2022 |
Assunção SS, Sperling RA, Ritchie C, Kerwin DR, Aisen PS, Lansdall C, Atri A, Cummings J. Meaningful benefits: a framework to assess disease-modifying therapies in preclinical and early Alzheimer's disease. Alzheimer's Research & Therapy. 14: 54. PMID 35440022 DOI: 10.1186/s13195-022-00984-y |
0.551 |
|
| 2022 |
Young CB, Winer JR, Younes K, Cody KA, Betthauser TJ, Johnson SC, Schultz A, Sperling RA, Greicius MD, Cobos I, Poston KL, Mormino EC. Divergent Cortical Tau Positron Emission Tomography Patterns Among Patients With Preclinical Alzheimer Disease. Jama Neurology. PMID 35435938 DOI: 10.1001/jamaneurol.2022.0676 |
0.375 |
|
| 2022 |
Guzmán-Vélez E, Diez I, Schoemaker D, Pardilla-Delgado E, Vila-Castelar C, Fox-Fuller JT, Baena A, Sperling RA, Johnson KA, Lopera F, Sepulcre J, Quiroz YT. Amyloid-β and tau pathologies relate to distinctive brain dysconnectomics in preclinical autosomal-dominant Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 119: e2113641119. PMID 35380901 DOI: 10.1073/pnas.2113641119 |
0.439 |
|
| 2022 |
Farrell ME, Papp KV, Buckley RF, Jacobs HIL, Schultz AP, Properzi MJ, Vannini P, Hanseeuw BJ, Rentz DM, Johnson KA, Sperling RA. Association of Emerging β-Amyloid and Tau Pathology With Early Cognitive Changes in Clinically Normal Older Adults. Neurology. PMID 35338074 DOI: 10.1212/WNL.0000000000200137 |
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| 2022 |
Prokopiou PC, Engels-Domínguez N, Papp KV, Scott MR, Schultz AP, Schneider C, Farrell ME, Buckley RF, Quiroz YT, El Fakhri G, Rentz DM, Sperling RA, Johnson KA, Jacobs HIL. Lower novelty-related locus coeruleus function is associated with Aβ-related cognitive decline in clinically healthy individuals. Nature Communications. 13: 1571. PMID 35322012 DOI: 10.1038/s41467-022-28986-2 |
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| 2022 |
Jacobs HIL, Becker JA, Kwong K, Munera D, Ramirez-Gomez L, Engels-Domínguez N, Sanchez JS, Vila-Castelar C, Baena A, Sperling RA, Johnson KA, Lopera F, Quiroz YT. Waning locus coeruleus integrity precedes cortical tau accrual in preclinical autosomal dominant Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35298083 DOI: 10.1002/alz.12656 |
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| 2022 |
Jacobs HIL, O'Donnell A, Satizabal CL, Lois C, Kojis D, Hanseeuw BJ, Thibault E, Sanchez JS, Buckley RF, Yang Q, DeCarli C, Killiany R, Sargurupremraj M, Sperling RA, Johnson KA, et al. Associations Between Brainstem Volume and Alzheimer's Disease Pathology in Middle-Aged Individuals of the Framingham Heart Study. Journal of Alzheimer's Disease : Jad. PMID 35213372 DOI: 10.3233/JAD-215372 |
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Grober E, Lipton RB, Sperling RA, Papp KV, Johnson KA, Rentz DM, Veroff AE, Aisen PS, Ezzati A. Associations of Stages of Objective Memory Impairment (SOMI) with Amyloid PET and Structural MRI: The A4 Study. Neurology. PMID 35197359 DOI: 10.1212/WNL.0000000000200046 |
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Munro CE, Buckley R, Vannini P, DeMuro C, Sperling R, Rentz DM, Johnson K, Gatchel JR, Amariglio R. Longitudinal Trajectories of Participant- and Study Partner-Rated Cognitive Decline, in Relation to Alzheimer's Disease Biomarkers and Mood Symptoms. Frontiers in Aging Neuroscience. 13: 806432. PMID 35173601 DOI: 10.3389/fnagi.2021.806432 |
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Petersen KK, Grober E, Lipton RB, Sperling RA, Buckley RF, Aisen PS, Ezzati A. Impact of sex and ε4 on the association of cognition and hippocampal volume in clinically normal, amyloid positive adults. Alzheimer's & Dementia (Amsterdam, Netherlands). 14: e12271. PMID 35155730 DOI: 10.1002/dad2.12271 |
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Jansen WJ, Janssen O, Tijms BM, Vos SJB, Ossenkoppele R, Visser PJ, Aarsland D, Alcolea D, Altomare D, von Arnim C, Baiardi S, Baldeiras I, Barthel H, Bateman RJ, ... ... Sperling RA, et al. Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum. Jama Neurology. PMID 35099509 DOI: 10.1001/jamaneurol.2021.5216 |
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Jutten RJ, Rentz DM, Fu JF, Mayblyum DV, Amariglio RE, Buckley RF, Properzi MJ, Maruff P, Stark CE, Yassa MA, Johnson KA, Sperling RA, Papp KV. Monthly At-Home Computerized Cognitive Testing to Detect Diminished Practice Effects in Preclinical Alzheimer's Disease. Frontiers in Aging Neuroscience. 13: 800126. PMID 35095476 DOI: 10.3389/fnagi.2021.800126 |
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Chhatwal JP, Schultz SA, McDade E, Schultz AP, Liu L, Hanseeuw BJ, Joseph-Mathurin N, Feldman R, Fitzpatrick CD, Sparks KP, Levin J, Berman SB, Renton AE, Esposito BT, Fernandez MV, ... ... Sperling RA, et al. Variant-dependent heterogeneity in amyloid β burden in autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analyses of an observational study. The Lancet. Neurology. 21: 140-152. PMID 35065037 DOI: 10.1016/S1474-4422(21)00375-6 |
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Grober E, Papp KV, Rentz DM, Sperling RA, Johnson KA, Amariglio RE, Schultz A, Lipton RB, Ezzati A. Neuroimaging correlates of Stages of Objective Memory Impairment (SOMI) system. Alzheimer's & Dementia (Amsterdam, Netherlands). 13: e12224. PMID 35005192 DOI: 10.1002/dad2.12224 |
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Papp KV, Samaroo A, Chou HC, Buckley R, Schneider OR, Hsieh S, Soberanes D, Quiroz Y, Properzi M, Schultz A, García-Magariño I, Marshall GA, Burke JG, Kumar R, Snyder N, ... ... Sperling RA, et al. Unsupervised mobile cognitive testing for use in preclinical Alzheimer's disease. Alzheimer's & Dementia (Amsterdam, Netherlands). 13: e12243. PMID 34621977 DOI: 10.1002/dad2.12243 |
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Jacobs HIL, Becker JA, Kwong K, Engels-Domínguez N, Prokopiou PC, Papp KV, Properzi M, Hampton OL, d'Oleire Uquillas F, Sanchez JS, Rentz DM, El Fakhri G, Normandin MD, Price JC, Bennett DA, Sperling RA, et al. In vivo and neuropathology data support locus coeruleus integrity as indicator of Alzheimer's disease pathology and cognitive decline. Science Translational Medicine. 13: eabj2511. PMID 34550726 DOI: 10.1126/scitranslmed.abj2511 |
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McDade E, Voytyuk I, Aisen P, Bateman RJ, Carrillo MC, De Strooper B, Haass C, Reiman EM, Sperling R, Tariot PN, Yan R, Masters CL, Vassar R, Lichtenthaler SF. The case for low-level BACE1 inhibition for the prevention of Alzheimer disease. Nature Reviews. Neurology. PMID 34548654 DOI: 10.1038/s41582-021-00545-1 |
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Fox-Fuller JT, Torrico-Teave H, d'Oleire Uquillas F, Chen K, Su Y, Chen Y, Brickhouse M, Sanchez JS, Aguero C, Jacobs HIL, Hampton O, Guzmán-Vélez E, Vila-Castelar C, Aguirre-Acevedo DC, Baena A, ... ... Sperling RA, et al. Cortical thickness across the lifespan in a Colombian cohort with autosomal-dominant Alzheimer's disease: A cross-sectional study. Alzheimer's & Dementia (Amsterdam, Netherlands). 13: e12233. PMID 34541287 DOI: 10.1002/dad2.12233 |
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Ngolab J, Donohue M, Belsha A, Salazar J, Cohen P, Jaiswal S, Tan V, Gessert D, Korouri S, Aggarwal NT, Alber J, Johnson K, Jicha G, van Dyck C, Lah J, ... Sperling RA, et al. Feasibility study for detection of retinal amyloid in clinical trials: The Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) trial. Alzheimer's & Dementia (Amsterdam, Netherlands). 13: e12199. PMID 34430703 DOI: 10.1002/dad2.12199 |
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Raman R, Quiroz YT, Langford O, Choi J, Ritchie M, Baumgartner M, Rentz D, Aggarwal NT, Aisen P, Sperling R, Grill JD. Disparities by Race and Ethnicity Among Adults Recruited for a Preclinical Alzheimer Disease Trial. Jama Network Open. 4: e2114364. PMID 34228129 DOI: 10.1001/jamanetworkopen.2021.14364 |
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Mayblyum DV, Becker JA, Jacobs HIL, Buckley RF, Schultz AP, Sepulcre J, Sanchez JS, Rubinstein ZB, Katz SR, Moody KA, Vannini P, Papp KV, Rentz DM, Price JC, Sperling RA, et al. Comparing PET and MRI Biomarkers Predicting Cognitive Decline in Preclinical Alzheimer Disease. Neurology. PMID 33952655 DOI: 10.1212/WNL.0000000000012108 |
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Belloy ME, Eger SJ, Le Guen Y, Napolioni V, Deters KD, Yang HS, Scelsi MA, Porter T, James SN, Wong A, Schott JM, Sperling RA, Laws SM, Mormino EC, He Z, et al. KL∗VS heterozygosity reduces brain amyloid in asymptomatic at-risk APOE∗4 carriers. Neurobiology of Aging. 101: 123-129. PMID 33610961 DOI: 10.1016/j.neurobiolaging.2021.01.008 |
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Guzmán-Vélez E, Zetterberg H, Fox-Fuller JT, Vila-Castelar C, Sanchez JS, Baena A, Garcia-Ospina G, Aguillon D, Pardilla-Delgado E, Gatchel JR, Sperling RA, Johnson K, Reiman EM, Blennow K, Lopera F, et al. Associations between plasma neurofilament light, in vivo brain pathology, and cognition in non-demented individuals with autosomal-dominant Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33527648 DOI: 10.1002/alz.12248 |
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Sanchez JS, Becker JA, Jacobs HIL, Hanseeuw BJ, Jiang S, Schultz AP, Properzi MJ, Katz SR, Beiser A, Satizabal CL, O'Donnell A, DeCarli C, Killiany R, El Fakhri G, Normandin MD, ... Sperling RA, et al. The cortical origin and initial spread of medial temporal tauopathy in Alzheimer's disease assessed with positron emission tomography. Science Translational Medicine. 13. PMID 33472953 DOI: 10.1126/scitranslmed.abc0655 |
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Sperling R, Henley D, Aisen PS, Raman R, Donohue MC, Ernstrom K, Rafii MS, Streffer J, Shi Y, Karcher K, Raghavan N, Tymofyeyev Y, Bogert J, Brashear HR, Novak G, et al. Findings of Efficacy, Safety, and Biomarker Outcomes of Atabecestat in Preclinical Alzheimer Disease: A Truncated Randomized Phase 2b/3 Clinical Trial. Jama Neurology. PMID 33464300 DOI: 10.1001/jamaneurol.2020.4857 |
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Sanchez JS, Hanseeuw BJ, Lopera F, Sperling RA, Baena A, Bocanegra Y, Aguillon D, Guzmán-Vélez E, Pardilla-Delgado E, Ramirez-Gomez L, Vila-Castelar C, Martinez JE, Fox-Fuller JT, Ramos C, Ochoa-Escudero M, et al. Longitudinal amyloid and tau accumulation in autosomal dominant Alzheimer's disease: findings from the Colombia-Boston (COLBOS) biomarker study. Alzheimer's Research & Therapy. 13: 27. PMID 33451357 DOI: 10.1186/s13195-020-00765-5 |
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Samaroo A, Amariglio RE, Burnham S, Sparks P, Properzi M, Schultz AP, Buckley R, Johnson KA, Sperling RA, Rentz DM, Papp KV. Diminished Learning Over Repeated Exposures (LORE) in preclinical Alzheimer's disease. Alzheimer's & Dementia (Amsterdam, Netherlands). 12: e12132. PMID 33426266 DOI: 10.1002/dad2.12132 |
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Chhatwal JP, Schultz AP, Dang Y, Ostaszewski B, Liu L, Yang HS, Johnson KA, Sperling RA, Selkoe DJ. Plasma N-terminal tau fragment levels predict future cognitive decline and neurodegeneration in healthy elderly individuals. Nature Communications. 11: 6024. PMID 33247134 DOI: 10.1038/s41467-020-19543-w |
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Farrell ME, Jiang S, Schultz AP, Properzi MJ, Price JC, Becker JA, Jacobs HIL, Hanseeuw BJ, Rentz DM, Villemagne VL, Papp KV, Mormino EC, Betensky RA, Johnson KA, Sperling RA, et al. Defining the lowest threshold for amyloid-PET to predict future cognitive decline and amyloid accumulation. Neurology. PMID 33199430 DOI: 10.1212/WNL.0000000000011214 |
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Marshall GA, Sikkes SAM, Amariglio RE, Gatchel JR, Rentz DM, Johnson KA, Langford O, Sun CK, Donohue MC, Raman R, Aisen PS, Sperling RA, Galasko DR. Instrumental activities of daily living, amyloid, and cognition in cognitively normal older adults screening for the A4 Study. Alzheimer's & Dementia (Amsterdam, Netherlands). 12: e12118. PMID 33163609 DOI: 10.1002/dad2.12118 |
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Dubbelman MA, Jutten RJ, Tomaszewski Farias SE, Amariglio RE, Buckley RF, Visser PJ, Rentz DM, Johnson KA, Properzi MJ, Schultz A, Donovan N, Gatchell JR, Teunissen CE, Van Berckel BNM, Van der Flier WM, Sperling RA, et al. Decline in cognitively complex everyday activities accelerates along the Alzheimer's disease continuum. Alzheimer's Research & Therapy. 12: 138. PMID 33121534 DOI: 10.1186/s13195-020-00706-2 |
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Jutten RJ, Sikkes SAM, Amariglio RE, Buckley RF, Properzi MJ, Marshall GA, Rentz DM, Johnson KA, Teunissen CE, Van Berckel BNM, Van der Flier WM, Scheltens P, Sperling RA, Papp KV, et al. Identifying Sensitive Measures of Cognitive Decline at Different Clinical Stages of Alzheimer's Disease. Journal of the International Neuropsychological Society : Jins. 1-13. PMID 33046162 DOI: 10.1017/S1355617720000934 |
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Hampton OL, Buckley RF, Manning LK, Scott MR, Properzi MJ, Peña-Gómez C, Jacobs HIL, Chhatwal JP, Johnson KA, Sperling RA, Schultz AP. Resting-state functional connectivity and amyloid burden influence longitudinal cortical thinning in the default mode network in preclinical Alzheimer's disease. Neuroimage. Clinical. 28: 102407. PMID 32942175 DOI: 10.1016/J.Nicl.2020.102407 |
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Walter S, Langford OG, Clanton TB, Jimenez-Maggiora GA, Raman R, Rafii MS, Shaffer EJ, Sperling RA, Cummings JL, Aisen PS. The Trial-Ready Cohort for Preclinical and Prodromal Alzheimer's Disease (TRC-PAD): Experience from the First 3 Years. The Journal of Prevention of Alzheimer's Disease. 7: 234-241. PMID 32920625 DOI: 10.14283/jpad.2020.47 |
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Jimenez-Maggiora GA, Bruschi S, Raman R, Langford O, Donohue M, Rafii MS, Sperling RA, Cummings JL, Aisen PS. TRC-PAD: Accelerating Recruitment of AD Clinical Trials through Innovative Information Technology. The Journal of Prevention of Alzheimer's Disease. 7: 226-233. PMID 32920624 DOI: 10.14283/jpad.2020.48 |
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Walter S, Clanton TB, Langford OG, Rafii MS, Shaffer EJ, Grill JD, Jimenez-Maggiora GA, Sperling RA, Cummings JL, Aisen PS. Recruitment into the Alzheimer Prevention Trials (APT) Webstudy for a Trial-Ready Cohort for Preclinical and Prodromal Alzheimer's Disease (TRC-PAD). The Journal of Prevention of Alzheimer's Disease. 7: 219-225. PMID 32920623 DOI: 10.14283/jpad.2020.46 |
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Langford O, Raman R, Sperling RA, Cummings J, Sun CK, Jimenez-Maggiora G, Aisen PS, Donohue MC. Predicting Amyloid Burden to Accelerate Recruitment of Secondary Prevention Clinical Trials. The Journal of Prevention of Alzheimer's Disease. 7: 213-218. PMID 32920622 DOI: 10.14283/jpad.2020.44 |
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Aisen PS, Sperling RA, Cummings J, Donohue MC, Langford O, Jimenez-Maggiora GA, Rissman RA, Rafii MS, Walter S, Clanton T, Raman R. The Trial-Ready Cohort for Preclinical/Prodromal Alzheimer's Disease (TRC-PAD) Project: An Overview. The Journal of Prevention of Alzheimer's Disease. 7: 208-212. PMID 32920621 DOI: 10.14283/jpad.2020.45 |
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Vila-Castelar C, Muñoz N, Papp KV, Amariglio RE, Baena A, Guzmán-Vélez E, Bocanegra Y, Sanchez JS, Reiman EM, Johnson KA, Sperling RA, Lopera F, Rentz DM, Quiroz YT. The Latin American Spanish version of the Face-Name Associative Memory Exam is sensitive to cognitive and pathological changes in preclinical autosomal dominant Alzheimer's disease. Alzheimer's Research & Therapy. 12: 104. PMID 32912283 DOI: 10.1186/s13195-020-00671-w |
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Dumitrescu L, Mahoney ER, Mukherjee S, Lee ML, Bush WS, Engelman CD, Lu Q, Fardo DW, Trittschuh EH, Mez J, Kaczorowski C, Hernandez Saucedo H, Widaman KF, Buckley R, Properzi M, ... Sperling RA, et al. Genetic variants and functional pathways associated with resilience to Alzheimer's disease. Brain : a Journal of Neurology. 143: 2561-2575. PMID 32844198 DOI: 10.1093/Brain/Awaa209 |
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Norton DJ, Parra MA, Sperling RA, Baena A, Guzman-Velez E, Jin DS, Andrea N, Khang J, Schultz A, Rentz DM, Pardilla-Delgado E, Fuller J, Johnson K, Reiman EM, Lopera F, et al. Visual short-term memory relates to tau and amyloid burdens in preclinical autosomal dominant Alzheimer's disease. Alzheimer's Research & Therapy. 12: 99. PMID 32825838 DOI: 10.1186/S13195-020-00660-Z |
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Buckley RF, Scott MR, Jacobs HI, Schultz AP, Properzi MJ, Amarglio RE, Hohman TJ, Mayblyum DV, Rubinstein ZB, Manning L, Hanseeuw BJ, Mormino EC, Rentz DM, Johnson KA, Sperling RA. Sex mediates relationships between regional tau pathology and cognitive decline. Annals of Neurology. PMID 32799367 DOI: 10.1002/Ana.25878 |
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Grill JD, Raman R, Ernstrom K, Sultzer DL, Burns JM, Donohue MC, Johnson KA, Aisen PS, Sperling RA, Karlawish J. Short-term Psychological Outcomes of Disclosing Amyloid Imaging Results to Research Participants Who Do Not Have Cognitive Impairment. Jama Neurology. PMID 32777010 DOI: 10.1001/Jamaneurol.2020.2734 |
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Guzmán-Vélez E, Martínez J, Papp K, Baena A, Vila-Castelar C, Artola A, Schultz AP, Bocanegra Y, Sanchez J, Rentz D, Tariot PN, Reiman EM, Sperling R, Johnson KA, Lopera F, et al. Associative memory and in vivo brain pathology in asymptomatic presenilin-1 E280A carriers. Neurology. PMID 32611637 DOI: 10.1212/Wnl.0000000000010177 |
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Raghavan NS, Dumitrescu L, Mormino E, Mahoney ER, Lee AJ, Gao Y, Bilgel M, Goldstein D, Harrison T, Engelman CD, Saykin AJ, Whelan CD, Liu JZ, Jagust W, Albert M, ... ... Sperling R, et al. Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease. Jama Neurology. PMID 32568366 DOI: 10.1001/Jamaneurol.2020.1760 |
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Schultz SA, Strain JF, Adedokun A, Wang Q, Preische O, Kuhle J, Flores S, Keefe S, Dincer A, Ances BM, Berman SB, Brickman AM, Cash DM, Chhatwal J, Cruchaga C, ... ... Sperling R, et al. Serum neurofilament light chain levels are associated with white matter integrity in autosomal dominant Alzheimer's disease. Neurobiology of Disease. 104960. PMID 32522711 DOI: 10.1016/J.Nbd.2020.104960 |
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Scott MR, Hampton OL, Buckley RF, Chhatwal JP, Hanseeuw BJ, Jacobs HIL, Properzi MJ, Sanchez JS, Johnson KA, Sperling RA, Schultz AP. Inferior temporal tau is associated with accelerated prospective cortical thinning in clinically normal older adults. Neuroimage. 116991. PMID 32512123 DOI: 10.1016/J.Neuroimage.2020.116991 |
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Aisen PS, Cummings J, Doody R, Kramer L, Salloway S, Selkoe DJ, Sims J, Sperling RA, Vellas B. The Future of Anti-Amyloid Trials. The Journal of Prevention of Alzheimer's Disease. 7: 146-151. PMID 32463066 DOI: 10.14283/jpad.2020.24 |
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Insel PS, Donohue MC, Sperling R, Hansson O, Mattsson-Carlgren N. The A4 study: β-amyloid and cognition in 4432 cognitively unimpaired adults. Annals of Clinical and Translational Neurology. PMID 32315118 DOI: 10.1002/Acn3.51048 |
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Jacobs HIL, Augustinack JC, Schultz AP, Hanseeuw BJ, Locascio J, Amariglio RE, Papp KV, Rentz DM, Sperling RA, Johnson KA. The presubiculum links incipient amyloid and tau pathology to memory function in older persons. Neurology. PMID 32273431 DOI: 10.1212/WNL.0000000000009362 |
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Sperling RA, Donohue MC, Raman R, Sun CK, Yaari R, Holdridge K, Siemers E, Johnson KA, Aisen PS. Association of Factors With Elevated Amyloid Burden in Clinically Normal Older Individuals. Jama Neurology. PMID 32250387 DOI: 10.1001/Jamaneurol.2020.0387 |
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Rabin JS, Shirzadi Z, Swardfager W, MacIntosh BJ, Schultz A, Yang HS, Buckley RF, Gatchel JR, Kirn D, Pruzin JJ, Hedden T, Lipsman N, Rentz DM, Black SE, Johnson KA, Sperling RA, et al. Amyloid-beta burden predicts prospective decline in body mass index in clinically normal adults. Neurobiology of Aging. PMID 32249013 DOI: 10.1016/J.Neurobiolaging.2020.03.002 |
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Biddle KD, Jacobs HIL, d'Oleire Uquillas F, Zide BS, Kirn DR, Properzi MR, Rentz DM, Johnson KA, Sperling RA, Donovan NJ. Associations of Widowhood and β-Amyloid With Cognitive Decline in Cognitively Unimpaired Older Adults. Jama Network Open. 3: e200121. PMID 32101313 DOI: 10.1001/jamanetworkopen.2020.0121 |
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Putcha D, Dickerson BC, Brickhouse M, Johnson KA, Sperling RA, Papp KV. Word retrieval across the biomarker-confirmed Alzheimer's disease syndromic spectrum. Neuropsychologia. 107391. PMID 32057937 DOI: 10.1016/j.neuropsychologia.2020.107391 |
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Davidow J, Biddle K, Johnson K, Sperling R, Donovan N. INTERACTIVE ASSOCIATION OF LIVING ALONE AND AMYLOID-Β BURDEN WITH LONGITUDINAL COGNITION IN COGNITIVELY UNIMPAIRED OLDER ADULTS The American Journal of Geriatric Psychiatry. 28: S76. DOI: 10.1016/J.Jagp.2020.01.102 |
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Greenberg SM, Bacskai BJ, Hernandez-Guillamon M, Pruzin J, Sperling R, van Veluw SJ. Cerebral amyloid angiopathy and Alzheimer disease - one peptide, two pathways. Nature Reviews. Neurology. PMID 31827267 DOI: 10.1038/S41582-019-0281-2 |
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Jack CR, Holtzman DM, Sperling R. Dementia is not synonymous with Alzheimer's disease. Science Translational Medicine. 11. PMID 31826979 DOI: 10.1126/Scitranslmed.Aav0511 |
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Vannini P, Uquillas FD, Jacobs HIL, Sepulcre J, Gatchel J, Amariglio RE, Hanseeuw B, Papp KV, Hedden T, Rentz DM, Pascual-Leone A, Johnson KA, Sperling RA. Decreased meta-memory is associated with early tauopathy in cognitively unimpaired older adults. Neuroimage. Clinical. 24: 102097. PMID 31795044 DOI: 10.1016/J.Nicl.2019.102097 |
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Papp KV, Buckley R, Mormino E, Maruff P, Villemagne VL, Masters CL, Johnson KA, Rentz DM, Sperling RA, Amariglio RE. Clinical meaningfulness of subtle cognitive decline on longitudinal testing in preclinical AD. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31759879 DOI: 10.1016/J.Jalz.2019.09.074 |
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Schultz AP, Buckley RF, Hampton OL, Scott MR, Properzi MJ, Peña-Gómez C, Pruzin JJ, Yang HS, Johnson KA, Sperling RA, Chhatwal JP. Longitudinal degradation of the default/salience network axis in symptomatic individuals with elevated amyloid burden. Neuroimage. Clinical. 102052. PMID 31711955 DOI: 10.1016/J.Nicl.2019.102052 |
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Arboleda-Velasquez JF, Lopera F, O'Hare M, Delgado-Tirado S, Marino C, Chmielewska N, Saez-Torres KL, Amarnani D, Schultz AP, Sperling RA, Leyton-Cifuentes D, Chen K, Baena A, Aguillon D, Rios-Romenets S, et al. Resistance to autosomal dominant Alzheimer's disease in an APOE3 Christchurch homozygote: a case report. Nature Medicine. PMID 31686034 DOI: 10.1038/S41591-019-0611-3 |
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| 2019 |
Buckley RF, Sikkes S, Villemagne VL, Mormino EC, Rabin JS, Burnham S, Papp KV, Doré V, Masters CL, Properzi MJ, Schultz AP, Johnson KA, Rentz DM, Sperling RA, Amariglio RE. Using subjective cognitive decline to identify high global amyloid in community-based samples: A cross-cohort study. Alzheimer's & Dementia (Amsterdam, Netherlands). 11: 670-678. PMID 31673597 DOI: 10.1016/j.dadm.2019.08.004 |
0.33 |
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| 2019 |
Schultz A, Kloet RW, Sohrabi HR, van der Weerd L, van Rooden S, Wermer MJH, Grand Moursel L, Yaqub M, van Berckel BNM, Chatterjee P, Gardener SL, Taddei K, Fagan AM, Benzinger TL, Morris JC, ... Sperling R, et al. Amyloid Imaging of Dutch-type Hereditary Cerebral Amyloid Angiopathy Carriers. Annals of Neurology. PMID 31361916 DOI: 10.1002/Ana.25560 |
0.354 |
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| 2019 |
Rabin JS, Klein H, Kirn DR, Schultz AP, Yang HS, Hampton O, Jiang S, Buckley RF, Viswanathan A, Hedden T, Pruzin J, Yau WW, Guzmán-Vélez E, Quiroz YT, Properzi M, ... Sperling RA, et al. Associations of Physical Activity and β-Amyloid With Longitudinal Cognition and Neurodegeneration in Clinically Normal Older Adults. Jama Neurology. PMID 31312836 DOI: 10.1001/Jamaneurol.2019.1879 |
0.352 |
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| 2019 |
Biddle KD, Uquillas FD, Jacobs HIL, Zide B, Kirn DR, Rentz DM, Johnson KA, Sperling RA, Donovan NJ. Social Engagement and Amyloid-β-Related Cognitive Decline in Cognitively Normal Older Adults. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. PMID 31248770 DOI: 10.1016/j.jagp.2019.05.005 |
0.63 |
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| 2019 |
Rabin JS, Perea RD, Buckley RF, Johnson KA, Sperling RA, Hedden T. Synergism between fornix microstructure and beta amyloid accelerates memory decline in clinically normal older adults. Neurobiology of Aging. 81: 38-46. PMID 31207468 DOI: 10.1016/j.neurobiolaging.2019.05.005 |
0.378 |
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| 2019 |
Daiello LA, Racine AM, Yun Gou R, Marcantonio ER, Xie Z, Kunze LJ, Vlassakov KV, Inouye SK, Jones RN, Alsop D, Travison T, Arnold S, Cooper Z, Dickerson B, Fong T, ... ... Sperling R, et al. Postoperative Delirium and Postoperative Cognitive Dysfunction: Overlap and Divergence. Anesthesiology. PMID 31166241 DOI: 10.1097/Aln.0000000000002729 |
0.518 |
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| 2019 |
Hanseeuw BJ, Betensky RA, Jacobs HIL, Schultz AP, Sepulcre J, Becker JA, Cosio DMO, Farrell M, Quiroz YT, Mormino EC, Buckley RF, Papp KV, Amariglio RA, Dewachter I, Ivanoiu A, ... Sperling RA, et al. Association of Amyloid and Tau With Cognition in Preclinical Alzheimer Disease: A Longitudinal Study. Jama Neurology. PMID 31157827 DOI: 10.1001/Jamaneurol.2019.1424 |
0.805 |
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| 2019 |
Nelson PT, Dickson DW, Trojanowski JQ, Jack CR, Boyle PA, Arfanakis K, Rademakers R, Alafuzoff I, Attems J, Brayne C, Coyle-Gilchrist ITS, Chui HC, Fardo DW, Flanagan ME, Halliday G, ... Sperling RA, et al. Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report. Brain : a Journal of Neurology. PMID 31039256 DOI: 10.1093/Brain/Awz099 |
0.357 |
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| 2019 |
Henley D, Raghavan N, Sperling R, Aisen P, Raman R, Romano G. Preliminary Results of a Trial of Atabecestat in Preclinical Alzheimer's Disease. The New England Journal of Medicine. 380: 1483-1485. PMID 30970197 DOI: 10.1056/Nejmc1813435 |
0.574 |
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| 2019 |
Buckley RF, Mormino EC, Chhatwal J, Schultz AP, Rabin JS, Rentz DM, Acar D, Properzi MJ, Dumurgier J, Jacobs H, Gomez-Isla T, Johnson KA, Sperling RA, Hanseeuw BJ. Associations between baseline amyloid, sex, and APOE on subsequent tau accumulation in cerebrospinal fluid. Neurobiology of Aging. 78: 178-185. PMID 30947113 DOI: 10.1016/J.Neurobiolaging.2019.02.019 |
0.622 |
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| 2019 |
Fuller JT, Cronin-Golomb A, Gatchel JR, Norton DJ, Guzmán-Vélez E, Jacobs HIL, Hanseeuw B, Pardilla-Delgado E, Artola A, Baena A, Bocanegra Y, Kosik KS, Chen K, Tariot PN, Johnson K, Sperling RA, et al. Biological and Cognitive Markers of Presenilin1 E280A Autosomal Dominant Alzheimer's Disease: A Comprehensive Review of the Colombian Kindred. The Journal of Prevention of Alzheimer's Disease. 6: 112-120. PMID 30756118 DOI: 10.14283/jpad.2019.6 |
0.376 |
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| 2019 |
Hanseeuw BJ, Lopera F, Sperling RA, Norton DJ, Guzman-Velez E, Baena A, Pardilla-Delgado E, Schultz AP, Gatchel J, Jin D, Chen K, Reiman EM, Johnson KA, Quiroz YT. Striatal amyloid is associated with tauopathy and memory decline in familial Alzheimer's disease. Alzheimer's Research & Therapy. 11: 17. PMID 30717814 DOI: 10.1186/S13195-019-0468-1 |
0.372 |
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| 2019 |
Buckley RF, Mormino EC, Rabin JS, Hohman TJ, Landau S, Hanseeuw BJ, Jacobs HIL, Papp KV, Amariglio RE, Properzi MJ, Schultz AP, Kirn D, Scott MR, Hedden T, Farrell M, ... ... Sperling RA, et al. Sex Differences in the Association of Global Amyloid and Regional Tau Deposition Measured By Positron Emission Tomography in Clinically Normal Older Adults. Jama Neurology. PMID 30715078 DOI: 10.1001/Jamaneurol.2018.4693 |
0.627 |
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| 2019 |
Halawa OA, Gatchel JR, Amariglio RE, Rentz DM, Sperling RA, Johnson KA, Marshall GA. Inferior and medial temporal tau and cortical amyloid are associated with daily functional impairment in Alzheimer's disease. Alzheimer's Research & Therapy. 11: 14. PMID 30704519 DOI: 10.1186/s13195-019-0471-6 |
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| 2019 |
Tan CH, Bonham LW, Fan CC, Mormino EC, Sugrue LP, Broce IJ, Hess CP, Yokoyama JS, Rabinovici GD, Miller BL, Yaffe K, Schellenberg GD, Kauppi K, Holland D, McEvoy LK, ... Sperling RA, et al. Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration. Brain : a Journal of Neurology. PMID 30689776 DOI: 10.1093/Brain/Awy327 |
0.403 |
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| 2019 |
Marshall GA, Gatchel JR, Donovan NJ, Muniz MC, Schultz AP, Becker JA, Chhatwal JP, Hanseeuw BJ, Papp KV, Amariglio RE, Rentz DM, Sperling RA, Johnson KA. Regional Tau Correlates of Instrumental Activities of Daily Living and Apathy in Mild Cognitive Impairment and Alzheimer's Disease Dementia. Journal of Alzheimer's Disease : Jad. 67: 757-768. PMID 30689584 DOI: 10.3233/Jad-170578 |
0.419 |
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| 2019 |
Jagust W, Jack CR, Bennett DA, Blennow K, Haeberlein SB, Holtzman DM, Jessen F, Karlawish J, Liu E, Molinuevo JL, Montine T, Phelps C, Rankin KP, Rowe CC, Scheltens P, ... Sperling R, et al. "Alzheimer's disease" is neither "Alzheimer's clinical syndrome" nor "dementia". Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 15: 153-157. PMID 30642435 DOI: 10.1016/J.Jalz.2018.11.002 |
0.444 |
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| 2019 |
Sperling R, Cummings J, Donohue M, Aisen P. Global Alzheimer's Platform Trial Ready Cohorts for the Prevention of Alzheimer's Dementia. The Journal of Prevention of Alzheimer's Disease. 3: 185-187. PMID 29199318 DOI: 10.14283/jpad.2016.108 |
0.521 |
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| 2019 |
Djonlagic I, Chhatwal J, Schulz A, Hampton O, Kirn D, Papp K, Rentz D, Johnson K, Sperling R, Redline S. 0300 Linking Sleep Disturbances with Amyloid and Tau Imaging. Preliminary Findings from the Harvard Aging Brain Study Sleep. 42: A122-A123. DOI: 10.1093/Sleep/Zsz067.299 |
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| 2019 |
Yang H, Ge T, Finucane H, De Jager PL, Sperling RA. P4-496: MYELOID CELL-SPECIFIC ALZHEIMER'S DISEASE POLYGENIC RISK SCORE PREDICTS NEURODEGENERATION AND Aβ-RELATED COGNITIVE DECLINE IN COGNITIVELY NORMAL OLDER ADULTS Alzheimer's & Dementia. 15: P1503-P1504. DOI: 10.1016/j.jalz.2019.08.042 |
0.346 |
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| 2019 |
Henley D, Sperling RA, Aisen PS, Raman R, Donohue MC, Ernstrom K, Shi Y, Karcher K, Raghavan N, Tymofyeyev Y, Brashear R, Novak GP, Thipphawong J, Saad Z, Kolb HC, et al. FTS3-01-04: FINAL EFFICACY, SAFETY AND BIOMARKER RESULTS OF THE PHASE 2B/3 RANDOMIZED, DOUBLE-BLINDED, PLACEBO-CONTROLLED EARLY TRIAL OF ATABECESTAT IN PRECLINICAL ALZHEIMER'S DISEASE Alzheimer's & Dementia. 15: P873-P874. DOI: 10.1016/J.Jalz.2019.06.4621 |
0.43 |
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| 2019 |
Ying Lim YY, Sperling RA, Insel P, Maruff P, Johnson KA, Mormino EC. DISTINCT CONTRIBUTIONS OF BASELINE AND LONGITUDINAL AMYLOID PET MEASURES TO MEMORY DECLINE IN COGNITIVELY NORMAL OLDER ADULTS Alzheimer's & Dementia. 15: P179-P180. DOI: 10.1016/j.jalz.2019.06.4379 |
0.316 |
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| 2019 |
Sanchez JS, Lopera F, Sperling RA, Becker A, Artola A, Baena A, Jacobs HI, Hanseeuw BJ, Schultz AP, Gatchel JR, Katz S, Mayblyum D, Moody K, Price JC, Bocanegra Y, et al. P4-312: LONGITUDINAL PET MEASURES OF TAU AND AMYLOID ACCUMULATION IN AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE: FINDINGS FROM THE COLBOS PROJECT Alzheimer's & Dementia. 15: P1411-P1411. DOI: 10.1016/J.Jalz.2019.06.3982 |
0.319 |
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| 2019 |
Jacobs HI, Becker A, Sperling RA, Guzman-Velez E, Baena A, Uquillas Fd, Artola A, Pardilla-Delgado E, Gatchel JR, Reiman EM, Johnson KA, Lopera F, Quiroz YT. P2-425: LOCUS COERULEUS INTENSITY IS ASSOCIATED WITH EARLY AMYLOID AND TAU PATHOLOGY IN PRECLINICAL AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE Alzheimer's & Dementia. 15: P774-P775. DOI: 10.1016/J.Jalz.2019.06.2832 |
0.348 |
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| 2018 |
Vöglein J, Noachtar S, McDade E, Quaid KA, Salloway S, Ghetti B, Noble J, Berman S, Chhatwal J, Mori H, Fox N, Allegri R, Masters CL, Buckles V, Ringman JM, ... ... Sperling R, et al. Seizures as an early symptom of autosomal dominant Alzheimer's disease. Neurobiology of Aging. 76: 18-23. PMID 30616208 DOI: 10.1016/J.Neurobiolaging.2018.11.022 |
0.313 |
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| 2018 |
Rabin JS, Yang HS, Schultz AP, Hanseeuw BJ, Hedden T, Viswanathan A, Gatchel JR, Marshall GA, Kilpatrick E, Klein H, Rao V, Buckley RF, Yau WW, Kirn DR, Rentz DM, ... Sperling RA, et al. Vascular risk and β-amyloid are synergistically associated with cortical tau. Annals of Neurology. PMID 30565287 DOI: 10.1002/Ana.25399 |
0.371 |
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| 2018 |
d'Oleire Uquillas F, Jacobs HIL, Biddle KD, Properzi M, Hanseeuw B, Schultz AP, Rentz DM, Johnson KA, Sperling RA, Donovan NJ. Regional tau pathology and loneliness in cognitively normal older adults. Translational Psychiatry. 8: 282. PMID 30563962 DOI: 10.1038/s41398-018-0345-x |
0.839 |
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| 2018 |
Sperling RA, Mormino EC, Schultz AP, Betensky RA, Papp KV, Amariglio RE, Hanseeuw BJ, Buckley R, Chhatwal J, Hedden T, Marshall GA, Quiroz YT, Donovan NJ, Jackson J, Gatchel JR, et al. The impact of Aβ and tau on prospective cognitive decline in older individuals. Annals of Neurology. PMID 30549303 DOI: 10.1002/Ana.25395 |
0.686 |
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| 2018 |
Huijbers W, Schultz AP, Papp KV, LaPoint MR, Hanseeuw B, Chhatwal JP, Hedden T, Johnson KA, Sperling RA. Tau accumulation in clinically normal older adults is associated with hippocampal hyperactivity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30482786 DOI: 10.1523/Jneurosci.1397-18.2018 |
0.747 |
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| 2018 |
Chen Z, Mengel D, Keshavan A, Rissman RA, Billinton A, Perkinton M, Percival-Alwyn J, Schultz A, Properzi M, Johnson K, Selkoe DJ, Sperling RA, Patel P, Zetterberg H, Galasko D, et al. Learnings about the complexity of extracellular tau aid development of a blood-based screen for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30419228 DOI: 10.1016/J.Jalz.2018.09.010 |
0.501 |
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| 2018 |
Brashear HR, Ketter N, Bogert J, Di J, Salloway SP, Sperling R. Clinical Evaluation of Amyloid-Related Imaging Abnormalities in Bapineuzumab Phase III Studies. Journal of Alzheimer's Disease : Jad. PMID 30412493 DOI: 10.3233/Jad-180675 |
0.381 |
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| 2018 |
Sepulcre J, Grothe MJ, d'Oleire Uquillas F, Ortiz-Terán L, Diez I, Yang HS, Jacobs HIL, Hanseeuw BJ, Li Q, El-Fakhri G, Sperling RA, Johnson KA. Neurogenetic contributions to amyloid beta and tau spreading in the human cortex. Nature Medicine. PMID 30374196 DOI: 10.1038/S41591-018-0206-4 |
0.815 |
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| 2018 |
Müller S, Preische O, Sohrabi HR, Gräber S, Jucker M, Ringman JM, Martins RN, McDade E, Schofield PR, Ghetti B, Rossor M, Fox NN, Graff-Radford NR, Levin J, Danek A, ... ... Sperling R, et al. Relationship between physical activity, cognition, and Alzheimer pathology in autosomal dominant Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30266303 DOI: 10.1016/J.Jalz.2018.06.3059 |
0.475 |
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| 2018 |
McDade E, Wang G, Gordon BA, Hassenstab J, Benzinger TLS, Buckles V, Fagan AM, Holtzman DM, Cairns NJ, Goate AM, Marcus DS, Morris JC, Paumier K, Xiong C, Allegri R, ... Sperling RA, et al. Longitudinal cognitive and biomarker changes in dominantly inherited Alzheimer disease. Neurology. PMID 30217935 DOI: 10.1212/Wnl.0000000000006277 |
0.368 |
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| 2018 |
Hanseeuw BJ, Jonas V, Jackson J, Betensky RA, Rentz DM, Johnson KA, Sperling RA, Donovan NJ. Association of anxiety with subcortical amyloidosis in cognitively normal older adults. Molecular Psychiatry. PMID 30116029 DOI: 10.1038/s41380-018-0214-2 |
0.317 |
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| 2018 |
Guzmán-Vélez E, Jaimes S, Aguirre-Acevedo DC, Norton DJ, Papp KV, Amariglio R, Rentz D, Baena A, Henao E, Tirado V, Muñoz C, Giraldo M, Sperling RA, Lopera F, Quiroz YT. A Three-Factor Structure of Cognitive Functioning Among Carriers and Non-Carriers of Autosomal-Dominant Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 30040714 DOI: 10.1093/Arclin/Acw043.34 |
0.359 |
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| 2018 |
Salloway SP, Sperling R, Fox NC, Sabbagh MN, Honig LS, Porsteinsson AP, Rofael H, Ketter N, Wang D, Liu E, Carr S, Black RS, Brashear HR. Long-Term Follow Up of Patients with Mild-to-Moderate Alzheimer's Disease Treated with Bapineuzumab in a Phase III, Open-Label, Extension Study. Journal of Alzheimer's Disease : Jad. PMID 29914022 DOI: 10.3233/Jad-171157 |
0.39 |
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| 2018 |
Munro CE, Donovan NJ, Amariglio RE, Papp KV, Marshall GA, Rentz DM, Pascual-Leone A, Sperling RA, Locascio JJ, Vannini P. The Impact of Awareness of and Concern About Memory Performance on the Prediction of Progression From Mild Cognitive Impairment to Alzheimer Disease Dementia. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. PMID 29866588 DOI: 10.1016/j.jagp.2018.04.008 |
0.413 |
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| 2018 |
Buckley RF, Mormino EC, Amariglio RE, Properzi MJ, Rabin JS, Lim YY, Papp KV, Jacobs HIL, Burnham S, Hanseeuw BJ, Doré V, Dobson A, Masters CL, Waller M, Rowe CC, ... Sperling RA, et al. Sex, amyloid, and APOE ε4 and risk of cognitive decline in preclinical Alzheimer's disease: Findings from three well-characterized cohorts. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29803541 DOI: 10.1016/J.Jalz.2018.04.010 |
0.645 |
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| 2018 |
Rabin JS, Schultz AP, Hedden T, Viswanathan A, Marshall GA, Kilpatrick E, Klein H, Buckley RF, Yang HS, Properzi M, Rao V, Kirn DR, Papp KV, Rentz DM, Johnson KA, Sperling RA, et al. Interactive Associations of Vascular Risk and β-Amyloid Burden With Cognitive Decline in Clinically Normal Elderly Individuals: Findings From the Harvard Aging Brain Study. Jama Neurology. PMID 29799986 DOI: 10.1001/Jamaneurol.2018.1123 |
0.348 |
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| 2018 |
Hanseeuw BJ, Betensky RA, Mormino EC, Schultz AP, Sepulcre J, Becker JA, Jacobs HIL, Buckley RF, LaPoint MR, Vanini P, Donovan NJ, Chhatwal JP, Marshall GA, Papp KV, Amariglio RE, ... ... Sperling RA, et al. PET staging of amyloidosis using striatum. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29792874 DOI: 10.1016/J.Jalz.2018.04.011 |
0.605 |
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| 2018 |
Orlovsky I, Huijbers W, Hanseeuw BJ, Mormino EC, Hedden T, Buckley RF, LaPoint M, Rabin JS, Rentz DM, Johnson KA, Sperling RA, Papp KV. The relationship between recall of recently versus remotely encoded famous faces and amyloidosis in clinically normal older adults. Alzheimer's & Dementia (Amsterdam, Netherlands). 10: 121-129. PMID 29780861 DOI: 10.1016/J.Dadm.2017.11.003 |
0.718 |
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| 2018 |
Lee S, Zimmerman ME, Narkhede A, Nasrabady SE, Tosto G, Meier IB, Benzinger TLS, Marcus DS, Fagan AM, Fox NC, Cairns NJ, Holtzman DM, Buckles V, Ghetti B, McDade E, ... ... Sperling RA, et al. White matter hyperintensities and the mediating role of cerebral amyloid angiopathy in dominantly-inherited Alzheimer's disease. Plos One. 13: e0195838. PMID 29742105 DOI: 10.1371/Journal.Pone.0195838 |
0.33 |
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| 2018 |
Jack CR, Bennett DA, Blennow K, Carrillo MC, Dunn B, Haeberlein SB, Holtzman DM, Jagust W, Jessen F, Karlawish J, Liu E, Molinuevo JL, Montine T, Phelps C, Rankin KP, ... Sperling R, et al. NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 14: 535-562. PMID 29653606 DOI: 10.1016/J.Jalz.2018.02.018 |
0.498 |
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| 2018 |
Lee CM, Jacobs HIL, Marquié M, Becker JA, Andrea NV, Jin DS, Schultz AP, Frosch MP, Gómez-Isla T, Sperling RA, Johnson KA. 18F-Flortaucipir Binding in Choroid Plexus: Related to Race and Hippocampus Signal. Journal of Alzheimer's Disease : Jad. 62: 1691-1702. PMID 29614677 DOI: 10.3233/Jad-170840 |
0.538 |
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| 2018 |
Ge T, Sabuncu MR, Smoller JW, Sperling RA, Mormino EC. Dissociable influences ofε4 and polygenic risk of AD dementia on amyloid and cognition. Neurology. PMID 29592889 DOI: 10.1212/Wnl.0000000000005415 |
0.378 |
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| 2018 |
Chhatwal JP, Schultz AP, Johnson KA, Hedden T, Jaimes S, Benzinger TLS, Jack C, Ances BM, Ringman JM, Marcus DS, Ghetti B, Farlow MR, Danek A, Levin J, Yakushev I, ... Sperling RA, et al. Preferential degradation of cognitive networks differentiates Alzheimer's disease from ageing. Brain : a Journal of Neurology. PMID 29522171 DOI: 10.1093/Brain/Awy053 |
0.34 |
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| 2018 |
Quiroz YT, Sperling RA, Norton DJ, Baena A, Arboleda-Velasquez JF, Cosio D, Schultz A, Lapoint M, Guzman-Velez E, Miller JB, Kim LA, Chen K, Tariot PN, Lopera F, Reiman EM, et al. Association Between Amyloid and Tau Accumulation in Young Adults With Autosomal Dominant Alzheimer Disease. Jama Neurology. PMID 29435558 DOI: 10.1001/Jamaneurol.2017.4907 |
0.39 |
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| 2018 |
Liu E, Wang D, Sperling R, Salloway S, Fox NC, Blennow K, Scheltens P, Schmidt ME, Streffer J, Novak G, Einstein S, Booth K, Ketter N, Brashear HR. Biomarker pattern of ARIA-E participants in phase 3 randomized clinical trials with bapineuzumab. Neurology. PMID 29429971 DOI: 10.1212/Wnl.0000000000005060 |
0.308 |
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| 2018 |
Jacobs HIL, Hedden T, Schultz AP, Sepulcre J, Perea RD, Amariglio RE, Papp KV, Rentz DM, Sperling RA, Johnson KA. Structural tract alterations predict downstream tau accumulation in amyloid-positive older individuals. Nature Neuroscience. PMID 29403032 DOI: 10.1038/s41593-018-0070-z |
0.672 |
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| 2018 |
Klinger RY, James OG, Borges-Neto S, Bisanar T, Li YJ, Qi W, Berger M, Terrando N, Newman MF, Doraiswamy PM, Mathew JP, Weiner MW, Aisen P, Weiner M, Aisen P, ... ... Sperling RA, ... ... Sperling RA, et al. 18F-florbetapir Positron Emission Tomography-determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery. Anesthesiology. PMID 29389750 DOI: 10.1097/Aln.0000000000002103 |
0.742 |
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| 2018 |
d'Oleire Uquillas F, Jacobs HIL, Hanseeuw B, Marshall GA, Properzi M, Schultz AP, LaPoint MR, Johnson KA, Sperling RA, Vannini P. Interactive versus additive relationships between regional cortical thinning and amyloid burden in predicting clinical decline in mild AD and MCI individuals. Neuroimage. Clinical. 17: 388-396. PMID 29159051 DOI: 10.1016/j.nicl.2017.10.034 |
0.842 |
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| 2017 |
Papp KV, Rentz DM, Orlovsky I, Sperling RA, Mormino EC. Optimizing the preclinical Alzheimer's cognitive composite with semantic processing: The PACC5. Alzheimer's & Dementia (New York, N. Y.). 3: 668-677. PMID 29264389 DOI: 10.1016/j.trci.2017.10.004 |
0.365 |
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| 2017 |
Touchon J, Rosenbaum J, Aisen P, Andrieu S, Carrillo MC, Ceccaldi M, Dartiques JF, Feldman H, Gabelle A, Isaac M, Fitten LJ, Sperling RA, Vellas B, Tariot P, Weiner M. Editorial: Collaborative Efforts to Prevent Alzheimer's Disease. The Journal of Nutrition, Health & Aging. 21: 1072-1074. PMID 29188862 DOI: 10.1007/S12603-017-0961-9 |
0.374 |
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| 2017 |
Buckley RF, Sparks KP, Papp KV, Dekhtyar M, Martin C, Burnham S, Sperling RA, Rentz DM. Computerized Cognitive Testing for Use in Clinical Trials: A Comparison of the NIH Toolbox and Cogstate C3 Batteries. The Journal of Prevention of Alzheimer's Disease. 4: 3-11. PMID 29188853 DOI: 10.14283/jpad.2017.1 |
0.315 |
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| 2017 |
Jackson JD, Rentz DM, Aghjayan SL, Buckley RF, Meneide TF, Sperling RA, Amariglio RE. Subjective cognitive concerns are associated with objective memory performance in Caucasian but not African-American persons. Age and Ageing. 46: 988-993. PMID 29088363 DOI: 10.1093/ageing/afx077 |
0.378 |
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| 2017 |
Dumurgier J, Hanseeuw BJ, Hatling FB, Judge KA, Schultz AP, Chhatwal JP, Blacker D, Sperling RA, Johnson KA, Hyman BT, Gómez-Isla T. Alzheimer's Disease Biomarkers and Future Decline in Cognitive Normal Older Adults. Journal of Alzheimer's Disease : Jad. PMID 29036824 DOI: 10.3233/Jad-170511 |
0.366 |
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| 2017 |
Buckley RF, Hanseeuw B, Schultz AP, Vannini P, Aghjayan SL, Properzi MJ, Jackson JD, Mormino EC, Rentz DM, Sperling RA, Johnson KA, Amariglio RE. Region-Specific Association of Subjective Cognitive Decline With Tauopathy Independent of Global β-Amyloid Burden. Jama Neurology. PMID 28973551 DOI: 10.1001/jamaneurol.2017.2216 |
0.405 |
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| 2017 |
Norton DJ, Amariglio R, Protas H, Chen K, Aguirre-Acevedo DC, Pulsifer B, Castrillon G, Tirado V, Munoz C, Tariot P, Langbaum JB, Reiman EM, Lopera F, Sperling RA, Quiroz YT. Subjective memory complaints in preclinical autosomal dominant Alzheimer disease. Neurology. PMID 28878053 DOI: 10.1212/Wnl.0000000000004533 |
0.303 |
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| 2017 |
Aisen PS, Cummings J, Jack CR, Morris JC, Sperling R, Frölich L, Jones RW, Dowsett SA, Matthews BR, Raskin J, Scheltens P, Dubois B. On the path to 2025: understanding the Alzheimer's disease continuum. Alzheimer's Research & Therapy. 9: 60. PMID 28793924 DOI: 10.1186/S13195-017-0283-5 |
0.578 |
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| 2017 |
Kinnunen KM, Cash DM, Poole T, Frost C, Benzinger TLS, Ahsan RL, Leung KK, Cardoso MJ, Modat M, Malone IB, Morris JC, Bateman RJ, Marcus DS, Goate A, Salloway S, ... ... Sperling RA, et al. Presymptomatic atrophy in autosomal dominant Alzheimer's disease: A serial MRI study. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28738187 DOI: 10.1016/J.Jalz.2017.06.2268 |
0.3 |
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| 2017 |
Gatchel JR, Donovan NJ, Locascio JJ, Schultz AP, Becker JA, Chhatwal J, Papp KV, Amariglio RE, Rentz DM, Blacker D, Sperling RA, Johnson KA, Marshall GA. Depressive Symptoms and Tau Accumulation in the Inferior Temporal Lobe and Entorhinal Cortex in Cognitively Normal Older Adults: A Pilot Study. Journal of Alzheimer's Disease : Jad. PMID 28697559 DOI: 10.3233/Jad-170001 |
0.326 |
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| 2017 |
Vannini P, Hanseeuw B, Munro CE, Amariglio RE, Marshall GA, Rentz DM, Pascual-Leone A, Johnson KA, Sperling RA. Anosognosia for memory deficits in mild cognitive impairment: Insight into the neural mechanism using functional and molecular imaging. Neuroimage. Clinical. 15: 408-414. PMID 28616381 DOI: 10.1016/j.nicl.2017.05.020 |
0.384 |
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| 2017 |
Donohue MC, Sperling RA, Petersen R, Sun CK, Weiner MW, Aisen PS. Association Between Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal Persons. Jama. 317: 2305-2316. PMID 28609533 DOI: 10.1001/Jama.2017.6669 |
0.504 |
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| 2017 |
Buckley RF, Schultz AP, Hedden T, Papp KV, Hanseeuw BJ, Marshall G, Sepulcre J, Smith EE, Rentz DM, Johnson KA, Sperling RA, Chhatwal JP. Functional network integrity presages cognitive decline in preclinical Alzheimer disease. Neurology. PMID 28592457 DOI: 10.1212/Wnl.0000000000004059 |
0.356 |
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| 2017 |
Sepulcre J, Grothe MJ, Sabuncu M, Chhatwal J, Schultz AP, Hanseeuw B, El Fakhri G, Sperling R, Johnson KA. Hierarchical Organization of Tau and Amyloid Deposits in the Cerebral Cortex. Jama Neurology. PMID 28558094 DOI: 10.1001/Jamaneurol.2017.0263 |
0.467 |
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| 2017 |
Dekhtyar M, Papp KV, Buckley R, Jacobs HIL, Schultz AP, Johnson KA, Sperling RA, Rentz DM. Neuroimaging Markers Associated with Maintenance of Optimal Memory Performance in Late-Life. Neuropsychologia. PMID 28472627 DOI: 10.1016/j.neuropsychologia.2017.04.037 |
0.548 |
|
| 2017 |
Müller S, Preische O, Sohrabi HR, Gräber S, Jucker M, Dietzsch J, Ringman JM, Martins RN, McDade E, Schofield PR, Ghetti B, Rossor M, Graff-Radford NR, Levin J, Galasko D, ... ... Sperling R, et al. Decreased body mass index in the preclinical stage of autosomal dominant Alzheimer's disease. Scientific Reports. 7: 1225. PMID 28450713 DOI: 10.1038/S41598-017-01327-W |
0.382 |
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| 2017 |
Gatchel JR, Donovan NJ, Locascio JJ, Becker JA, Rentz DM, Sperling RA, Johnson KA, Marshall GA. Regional 18F-Fluorodeoxyglucose Hypometabolism is Associated with Higher Apathy Scores Over Time in Early Alzheimer Disease. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. PMID 28410856 DOI: 10.1016/j.jagp.2016.12.017 |
0.407 |
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| 2017 |
Vannini P, Amariglio R, Hanseeuw B, Johnson KA, McLaren DG, Chhatwal J, Pascual-Leone A, Rentz D, Sperling RA. Memory self-awareness in the preclinical and prodromal stages of Alzheimer's disease. Neuropsychologia. PMID 28385579 DOI: 10.1016/J.Neuropsychologia.2017.04.002 |
0.397 |
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| 2017 |
Sepulcre J, Sabuncu MR, Li Q, El Fakhri G, Sperling R, Johnson KA. Tau and Aβ proteins distinctively associate to functional network changes in the aging brain. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28366797 DOI: 10.1016/J.Jalz.2017.02.011 |
0.429 |
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| 2017 |
Schultz AP, Chhatwal JP, Hedden T, Mormino EC, Hanseeuw BJ, Sepulcre J, Huijbers W, LaPoint M, Buckley RF, Johnson KA, Sperling RA. Phases of hyper and hypo connectivity in the Default Mode and Salience networks track with amyloid and Tau in clinically normal individuals. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28314821 DOI: 10.1523/Jneurosci.3263-16.2017 |
0.721 |
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| 2017 |
Papp KV, Rentz DM, Mormino EC, Schultz AP, Amariglio RE, Quiroz Y, Johnson KA, Sperling RA. Cued memory decline in biomarker-defined preclinical Alzheimer disease. Neurology. PMID 28283594 DOI: 10.1212/Wnl.0000000000003812 |
0.369 |
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| 2017 |
Hanseeuw BJ, Betensky RA, Schultz AP, Papp KV, Mormino EC, Sepulcre J, Bark JS, Cosio DM, LaPoint M, Chhatwal JP, Rentz DM, Sperling RA, Johnson K. FDG metabolism associated with tau-amyloid interaction predicts memory decline. Annals of Neurology. PMID 28253546 DOI: 10.1002/Ana.24910 |
0.364 |
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| 2017 |
Mormino EC, Papp KV, Rentz DM, Donohue MC, Amariglio R, Quiroz YT, Chhatwal J, Marshall GA, Donovan N, Jackson J, Gatchel JR, Hanseeuw BJ, Schultz AP, Aisen PS, Johnson KA, Sperling RA, et al. Early and late change on the preclinical Alzheimer's cognitive composite in clinically normal older individuals with elevated β-amyloid. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28253478 DOI: 10.1016/J.Jalz.2017.01.018 |
0.542 |
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| 2017 |
Huijbers W, Schultz AP, Papp KV, LaPoint MR, Chhatwal JP, Hedden T, Johnson K, Sperling RA. TAU ACCUMULATION IN CLINICALLY NORMAL OLDER ADULTS IS ASSOCIATED WITH INCREASES IN HIPPOCAMPAL FMRI ACTIVITY Alzheimer's & Dementia. 13: P1215. DOI: 10.1016/J.Jalz.2017.07.388 |
0.657 |
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| 2017 |
Papp KV, Mormino BC, Huijbers W, Dickerson BC, Orlovsky I, Schultz AP, Sperling RA, Rentz DM, Johnson K. SEMANTIC MEMORY AND PET AMYLOID AND TAU DEPOSITION IN PRECLINICAL AND PRODROMAL ALZHEIMER’S DISEASE Alzheimer's & Dementia. 13: P911-P912. DOI: 10.1016/J.Jalz.2017.07.333 |
0.746 |
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| 2017 |
Yang H, Yu L, White CC, Sperling RA, Bennett DA, Schneider JA, De Jager PL. [P2-115]: A TMEM106B
LOCUS IS IMPLICATED IN COGNITIVE DECLINE IN ALZHEIMER's DISEASE Alzheimer's & Dementia. 13: P650-P651. DOI: 10.1016/J.Jalz.2017.06.765 |
0.338 |
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| 2017 |
Yang H, Yu L, White CC, Sperling RA, De Jager PL, Bennett DA, Schneider JA. [P1-154]: APOE
ε4 IS ASSOCIATED WITH HIGHER TDP-43 PROTEINOPATHY BURDEN IN ALZHEIMER's DISEASE Alzheimer's & Dementia. 13: P301-P302. DOI: 10.1016/J.Jalz.2017.06.221 |
0.315 |
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| 2016 |
Cummings J, Aisen P, Barton R, Bork J, Doody R, Dwyer J, Egan JC, Feldman H, Lappin D, Truyen L, Salloway S, Sperling R, Vradenburg G. Re-Engineering Alzheimer Clinical Trials: Global Alzheimer's Platform Network. The Journal of Prevention of Alzheimer's Disease. 3: 114-120. PMID 28459045 DOI: 10.14283/jpad.2016.93 |
0.433 |
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| 2016 |
Prčkovska V, Huijbers W, Schultz A, Ortiz-Teran L, Peña-Gomez C, Villoslada P, Johnson K, Sperling R, Sepulcre J. Epicenters of dynamic connectivity in the adaptation of the ventral visual system. Human Brain Mapping. PMID 28029725 DOI: 10.1002/Hbm.23497 |
0.623 |
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| 2016 |
Molinuevo JL, Rabin LA, Amariglio R, Buckley R, Dubois B, Ellis KA, Ewers M, Hampel H, Klöppel S, Rami L, Reisberg B, Saykin AJ, Sikkes S, Smart CM, Snitz BE, Sperling R, et al. Implementation of subjective cognitive decline criteria in research studies. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27825022 DOI: 10.1016/J.Jalz.2016.09.012 |
0.456 |
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| 2016 |
Donovan NJ, Okereke OI, Vannini P, Amariglio RE, Rentz DM, Marshall GA, Johnson KA, Sperling RA. Association of Higher Cortical Amyloid Burden With Loneliness in Cognitively Normal Older Adults. Jama Psychiatry. PMID 27806159 DOI: 10.1001/jamapsychiatry.2016.2657 |
0.395 |
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| 2016 |
Shah H, Albanese E, Duggan C, Rudan I, Langa KM, Carrillo MC, Chan KY, Joanette Y, Prince M, Rossor M, Saxena S, Snyder HM, Sperling R, Varghese M, Wang H, et al. Research priorities to reduce the global burden of dementia by 2025. The Lancet. Neurology. 15: 1285-1294. PMID 27751558 DOI: 10.1016/S1474-4422(16)30235-6 |
0.311 |
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| 2016 |
Rentz DM, Mormino EC, Papp KV, Betensky RA, Sperling RA, Johnson KA. Cognitive resilience in clinical and preclinical Alzheimer's disease: the Association of Amyloid and Tau Burden on cognitive performance. Brain Imaging and Behavior. PMID 27738998 DOI: 10.1007/s11682-016-9640-4 |
0.358 |
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| 2016 |
Aghjayan SL, Buckley RF, Vannini P, Rentz DM, Jackson JD, Sperling RA, Johnson KA, Amariglio RE. The influence of demographic factors on subjective cognitive concerns and beta-amyloid. International Psychogeriatrics. 1-8. PMID 27724996 DOI: 10.1017/S1041610216001502 |
0.398 |
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| 2016 |
Zhang X, Mormino EC, Sun N, Sperling RA, Sabuncu MR, Yeo BT. Bayesian model reveals latent atrophy factors with dissociable cognitive trajectories in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 27702899 DOI: 10.1073/Pnas.1611073113 |
0.365 |
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| 2016 |
Albers AD, Asafu-Adjei J, Delaney MK, Kelly KE, Gomez-Isla T, Blacker D, Johnson KA, Sperling RA, Hyman BT, Betensky RA, Hastings L, Albers MW. Episodic Memory of Odors Stratifies Alzheimer Biomarkers in Normal Elderly. Annals of Neurology. PMID 27696605 DOI: 10.1002/Ana.24792 |
0.387 |
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| 2016 |
Gomperts SN, Locascio JJ, Makaretz SJ, Schultz A, Caso C, Vasdev N, Sperling R, Growdon JH, Dickerson BC, Johnson K. Tau Positron Emission Tomographic Imaging in the Lewy Body Diseases. Jama Neurology. PMID 27654968 DOI: 10.1001/Jamaneurol.2016.3338 |
0.56 |
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| 2016 |
Huijbers W, Papp KV, LaPoint M, Wigman SE, Dagley A, Hedden T, Rentz DM, Schultz AP, Sperling RA. Age-Related Increases in Tip-of-the-tongue are Distinct from Decreases in Remembering Names: A Functional MRI Study. Cerebral Cortex (New York, N.Y. : 1991). PMID 27578492 DOI: 10.1093/Cercor/Bhw234 |
0.67 |
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| 2016 |
Mormino EC, Papp KV, Rentz DM, Schultz AP, LaPoint M, Amariglio R, Hanseeuw B, Marshall GA, Hedden T, Johnson KA, Sperling RA. Heterogeneity in Suspected Non-Alzheimer Disease Pathophysiology Among Clinically Normal Older Individuals. Jama Neurology. PMID 27548655 DOI: 10.1001/jamaneurol.2016.2237 |
0.338 |
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| 2016 |
Buckley RF, Villemagne VL, Masters CL, Ellis KA, Rowe CC, Johnson K, Sperling R, Amariglio R. A Conceptualization of the Utility of Subjective Cognitive Decline in Clinical Trials of Preclinical Alzheimer's Disease. Journal of Molecular Neuroscience : Mn. PMID 27514526 DOI: 10.1007/S12031-016-0810-Z |
0.492 |
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| 2016 |
Hanseeuw BJ, Schultz AP, Betensky RA, Sperling RA, Johnson KA. Decreased hippocampal metabolism in high-amyloid mild cognitive impairment. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27421609 DOI: 10.1016/j.jalz.2016.06.2357 |
0.35 |
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| 2016 |
Sepulcre J, Schultz AP, Sabuncu M, Gomez-Isla T, Chhatwal J, Becker A, Sperling R, Johnson KA. In Vivo Tau, Amyloid, and Gray Matter Profiles in the Aging Brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 7364-74. PMID 27413148 DOI: 10.1523/Jneurosci.0639-16.2016 |
0.455 |
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| 2016 |
Mormino EC, Sperling RA, Holmes AJ, Buckner RL, De Jager PL, Smoller JW, Sabuncu MR. Polygenic risk of Alzheimer disease is associated with early- and late-life processes. Neurology. PMID 27385740 DOI: 10.1212/Wnl.0000000000002922 |
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| 2016 |
Jack CR, Bennett DA, Blennow K, Carrillo MC, Feldman HH, Frisoni GB, Hampel H, Jagust WJ, Johnson KA, Knopman DS, Petersen RC, Scheltens P, Sperling RA, Dubois B. A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers. Neurology. PMID 27371494 DOI: 10.1212/Wnl.0000000000002923 |
0.324 |
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| 2016 |
Tarrant SD, Bardach SH, Bates K, Nichols H, Towner J, Tamatha C, Caban-Holt A, Van-Eldik LJ, Murphy RR, Sperling R, Jicha GA. The Effectiveness of Small-group Community-based Information Sessions on Clinical Trial Recruitment for Secondary Prevention of Alzheimer's Disease. Alzheimer Disease and Associated Disorders. PMID 27213625 DOI: 10.1097/Wad.0000000000000151 |
0.341 |
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| 2016 |
Fotiadis P, van Rooden S, van der Grond J, Schultz A, Martinez-Ramirez S, Auriel E, Reijmer Y, van Opstal AM, Ayres A, Schwab KM, Alzheimer's Disease Neuroimaging Initiative Adni, Hedden T, Rosand J, Viswanathan A, Wermer M, ... Sperling RA, et al. Cortical atrophy in patients with cerebral amyloid angiopathy: a case-control study. The Lancet. Neurology. PMID 27180034 DOI: 10.1016/S1474-4422(16)30030-8 |
0.357 |
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| 2016 |
Weninger S, Carrillo MC, Dunn B, Aisen PS, Bateman RJ, Kotz JD, Langbaum JB, Mills SL, Reiman EM, Sperling R, Santacruz AM, Tariot PN, Welsh-Bohmer KA. Collaboration for Alzheimer's Prevention: Principles to guide data and sample sharing in preclinical Alzheimer's disease trials. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 12: 631-2. PMID 27157073 DOI: 10.1016/J.Jalz.2016.04.001 |
0.562 |
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| 2016 |
Rieckmann A, Van Dijk KR, Sperling RA, Johnson KA, Buckner RL, Hedden T. Accelerated decline in white matter integrity in clinically normal individuals at risk for Alzheimer's disease. Neurobiology of Aging. 42: 177-88. PMID 27143434 DOI: 10.1016/j.neurobiolaging.2016.03.016 |
0.356 |
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| 2016 |
Rabinovici GD, Karlawish J, Knopman D, Snyder HM, Sperling R, Carrillo MC. Testing and disclosures related to amyloid imaging and Alzheimer's disease: Common questions and fact sheet summary. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 12: 510-5. PMID 27103054 DOI: 10.1016/J.Jalz.2016.03.002 |
0.475 |
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| 2016 |
Hendrix JA, Bateman RJ, Brashear HR, Duggan C, Carrillo MC, Bain LJ, DeMattos R, Katz RG, Ostrowitzki S, Siemers E, Sperling R, Vitolo OV. Challenges, solutions, and recommendations for Alzheimer's disease combination therapy. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27017906 DOI: 10.1016/J.Jalz.2016.02.007 |
0.386 |
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| 2016 |
Lee S, Viqar F, Zimmerman ME, Narkhede A, Tosto G, Benzinger TL, Marcus DS, Fagan AM, Goate A, Fox NC, Cairns NJ, Holtzman DM, Buckles V, Ghetti B, McDade E, ... ... Sperling RA, et al. White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the Dominantly Inherited Alzheimer Network. Annals of Neurology. PMID 27016429 DOI: 10.1002/ana.24647 |
0.351 |
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| 2016 |
Dubois B, Hampel H, Feldman HH, Scheltens P, Aisen P, Andrieu S, Bakardjian H, Benali H, Bertram L, Blennow K, Broich K, Cavedo E, Crutch S, Dartigues JF, Duyckaerts C, ... ... Sperling R, et al. Preclinical Alzheimer's disease: Definition, natural history, and diagnostic criteria. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 12: 292-323. PMID 27012484 DOI: 10.1016/J.Jalz.2016.02.002 |
0.539 |
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| 2016 |
Su Y, Blazey TM, Owen CJ, Christensen JJ, Friedrichsen K, Joseph-Mathurin N, Wang Q, Hornbeck RC, Ances BM, Snyder AZ, Cash LA, Koeppe RA, Klunk WE, Galasko D, Brickman AM, ... ... Sperling RA, et al. Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group. Plos One. 11: e0152082. PMID 27010959 DOI: 10.1371/Journal.Pone.0152082 |
0.311 |
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| 2016 |
Rentz DM, Dekhtyar M, Sherman J, Burnham S, Blacker D, Aghjayan SL, Papp KV, Amariglio RE, Schembri A, Chenhall T, Maruff P, Aisen P, Hyman BT, Sperling RA. The Feasibility of At-Home iPad Cognitive Testing For Use in Clinical Trials. The Journal of Prevention of Alzheimer's Disease. 3: 8-12. PMID 26998469 DOI: 10.14283/jpad.2015.78 |
0.411 |
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| 2016 |
Molinuevo JL, Cami J, Carné X, Carrillo MC, Georges J, Isaac MB, Khachaturian Z, Kim SY, Morris JC, Pasquier F, Ritchie C, Sperling R, Karlawish J. Ethical challenges in preclinical Alzheimer's disease observational studies and trials: Results of the Barcelona summit. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26988427 DOI: 10.1016/J.Jalz.2016.01.009 |
0.399 |
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| 2016 |
Winblad B, Amouyel P, Andrieu S, Ballard C, Brayne C, Brodaty H, Cedazo-Minguez A, Dubois B, Edvardsson D, Feldman H, Fratiglioni L, Frisoni GB, Gauthier S, Georges J, Graff C, ... ... Sperling R, et al. Defeating Alzheimer's disease and other dementias: a priority for European science and society. The Lancet. Neurology. 15: 455-532. PMID 26987701 DOI: 10.1016/S1474-4422(16)00062-4 |
0.426 |
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| 2016 |
Jack CR, Knopman DS, Chételat G, Dickson D, Fagan AM, Frisoni GB, Jagust W, Mormino EC, Petersen RC, Sperling RA, van der Flier WM, Villemagne VL, Visser PJ, Vos SJ. Suspected non-Alzheimer disease pathophysiology - concept and controversy. Nature Reviews. Neurology. PMID 26782335 DOI: 10.1038/Nrneurol.2015.251 |
0.34 |
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| 2016 |
Sperling R. Secondary prevention trials in preclinical Alzheimer's disease Neurobiology of Aging. 39. DOI: 10.1016/J.Neurobiolaging.2016.01.078 |
0.413 |
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| 2016 |
Aisen PS, Cummings JL, Sperling RA. F5-04-03: TRC-PAD: Using Run-In Data for Screen Failure Reduction Alzheimer's & Dementia. 12: P372-P372. DOI: 10.1016/J.Jalz.2016.06.697 |
0.306 |
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| 2016 |
Sperling RA, Aisen PS. F4-03-03: Anti-Amyloid Treatment of Asymptomatic Ad: A4 and Beyond Alzheimer's & Dementia. 12: P326-P327. DOI: 10.1016/J.Jalz.2016.06.598 |
0.426 |
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| 2016 |
Quiroz YT, Sperling RA, Baena A, Arboleda-Velasquez J, Schultz AP, Cosio DM, LaPoint MR, Judge K, Jaimes SY, Norton DJ, Reiman EM, Lopera F, Johnson K. IC-P-198: TAU and Amyloid PET Imaging in a Colombian Kindred with Autosomal-Dominant Alzheimer's Disease Alzheimer's & Dementia. 12: P143-P144. DOI: 10.1016/J.Jalz.2016.06.229 |
0.312 |
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| 2015 |
Masters CL, Bateman R, Blennow K, Rowe CC, Sperling RA, Cummings JL. Alzheimer's disease. Nature Reviews. Disease Primers. 1: 15056. PMID 27188934 DOI: 10.1038/nrdp.2015.56 |
0.315 |
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| 2015 |
Marshall GA, Dekhtyar M, Bruno JM, Jethwani K, Amariglio RE, Johnson KA, Sperling RA, Rentz DM. The Harvard Automated Phone Task: new performance-based activities of daily living tests for early Alzheimer's disease. The Journal of Prevention of Alzheimer's Disease. 2: 242-253. PMID 26665121 DOI: 10.14283/jpad.2015.72 |
0.367 |
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| 2015 |
Malishkevich A, Marshall GA, Schultz AP, Sperling RA, Aharon-Peretz J, Gozes I. Blood-Borne Activity-Dependent Neuroprotective Protein (ADNP) is Correlated with Premorbid Intelligence, Clinical Stage, and Alzheimer's Disease Biomarkers. Journal of Alzheimer's Disease : Jad. PMID 26639975 DOI: 10.3233/JAD-150799 |
0.404 |
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| 2015 |
Papp KV, Mormino EC, Amariglio RE, Munro C, Dagley A, Schultz AP, Johnson KA, Sperling RA, Rentz DM. Biomarker Validation of a Decline in Semantic Processing in Preclinical Alzheimer's Disease. Neuropsychology. PMID 26595826 DOI: 10.1037/neu0000246 |
0.406 |
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| 2015 |
Johnson KA, Schultz A, Betensky RA, Becker JA, Sepulcre J, Rentz D, Mormino E, Chhatwal J, Amariglio R, Papp K, Marshall G, Albers M, Mauro S, Pepin L, Alverio J, ... Sperling R, et al. Tau PET imaging in aging and early Alzheimer's disease. Annals of Neurology. PMID 26505746 DOI: 10.1002/Ana.24546 |
0.608 |
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| 2015 |
Reiman EM, Langbaum JB, Tariot PN, Lopera F, Bateman RJ, Morris JC, Sperling RA, Aisen PS, Roses AD, Welsh-Bohmer KA, Carrillo MC, Weninger S. CAP-advancing the evaluation of preclinical Alzheimer disease treatments. Nature Reviews. Neurology. PMID 26416539 DOI: 10.1038/Nrneurol.2015.177 |
0.522 |
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| 2015 |
Guercio BJ, Donovan NJ, Munro CE, Aghjayan SL, Wigman SE, Locascio JJ, Amariglio RE, Rentz DM, Johnson KA, Sperling RA, Marshall GA. The Apathy Evaluation Scale: A Comparison of Subject, Informant, and Clinician Report in Cognitively Normal Elderly and Mild Cognitive Impairment. Journal of Alzheimer's Disease : Jad. 47: 421-32. PMID 26401564 DOI: 10.3233/JAD-150146 |
0.369 |
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| 2015 |
Salloway S, Sperling R. Understanding Conflicting Neuropathological Findings in Patients Clinically Diagnosed as Having Alzheimer Dementia. Jama Neurology. 72: 1106-8. PMID 26302229 DOI: 10.1001/Jamaneurol.2015.1804 |
0.417 |
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| 2015 |
Hyman BT, Growdon JH, Albers MW, Buckner RL, Chhatwal J, Gomez-Isla MT, Haass C, Hudry E, Jack CR, Johnson KA, Khachaturian ZS, Kim DY, Martin JB, Nitsch RM, Rosen BR, ... ... Sperling RA, et al. Massachusetts Alzheimer's Disease Research Center: Progress and challenges. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26297855 DOI: 10.1016/J.Jalz.2015.06.1887 |
0.472 |
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| 2015 |
Vellas B, Bateman R, Blennow K, Frisoni G, Johnson K, Katz R, Langbaum J, Marson D, Sperling R, Wessels A, Salloway S, Doody R, Aisen P. Endpoints for Pre-Dementia AD Trials: A Report from the EU/US/CTAD Task Force. The Journal of Prevention of Alzheimer's Disease. 2: 128-135. PMID 26247004 DOI: 10.14283/jpad.2015.55 |
0.511 |
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| 2015 |
Sperling RA, Amariglio RE, Marshall GA, Rentz DM. Establishing Clinical Relevance in Preclinical Alzheimer's Disease. The Journal of Prevention of Alzheimer's Disease. 2: 85-87. PMID 26247003 DOI: 10.14283/jpad.2015.56 |
0.302 |
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| 2015 |
Wang F, Gordon BA, Ryman DC, Ma S, Xiong C, Hassenstab J, Goate A, Fagan AM, Cairns NJ, Marcus DS, McDade E, Ringman JM, Graff-Radford NR, Ghetti B, Farlow MR, Sperling R, et al. Cerebral amyloidosis associated with cognitive decline in autosomal dominant Alzheimer disease. Neurology. PMID 26245925 DOI: 10.1212/Wnl.0000000000001903 |
0.43 |
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| 2015 |
Toledo JB, Zetterberg H, van Harten AC, Glodzik L, Martinez-Lage P, Bocchio-Chiavetto L, Rami L, Hansson O, Sperling R, Engelborghs S, Osorio RS, Vanderstichele H, Vandijck M, Hampel H, Teipl S, et al. Alzheimer's disease cerebrospinal fluid biomarker in cognitively normal subjects. Brain : a Journal of Neurology. 138: 2701-15. PMID 26220940 DOI: 10.1093/Brain/Awv199 |
0.558 |
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| 2015 |
Liu E, Schmidt ME, Margolin R, Sperling R, Koeppe R, Mason NS, Klunk WE, Mathis CA, Salloway S, Fox NC, Hill DL, Les AS, Collins P, Gregg KM, Di J, et al. Amyloid-β 11C-PiB-PET imaging results from 2 randomized bapineuzumab phase 3 AD trials. Neurology. PMID 26208959 DOI: 10.1212/Wnl.0000000000001877 |
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| 2015 |
Quiroz YT, Schultz AP, Chen K, Protas HD, Brickhouse M, Fleisher AS, Langbaum JB, Thiyyagura P, Fagan AM, Shah AR, Muniz M, Arboleda-Velasquez JF, Munoz C, Garcia G, Acosta-Baena N, ... ... Sperling RA, et al. Brain Imaging and Blood Biomarker Abnormalities in Children With Autosomal Dominant Alzheimer Disease: A Cross-Sectional Study. Jama Neurology. PMID 26121081 DOI: 10.1001/Jamaneurol.2015.1099 |
0.474 |
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| 2015 |
Doody RS, Raman R, Sperling RA, Seimers E, Sethuraman G, Mohs R, Farlow M, Iwatsubo T, Vellas B, Sun X, Ernstrom K, Thomas RG, Aisen PS. Peripheral and central effects of γ-secretase inhibition by semagacestat in Alzheimer's disease. Alzheimer's Research & Therapy. 7: 36. PMID 26064192 DOI: 10.1186/S13195-015-0121-6 |
0.48 |
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| 2015 |
Gidicsin CM, Maye JE, Locascio JJ, Pepin LC, Philiossaint M, Becker JA, Younger AP, Dekhtyar M, Schultz AP, Amariglio RE, Marshall GA, Rentz DM, Hedden T, Sperling RA, Johnson KA. Cognitive activity relates to cognitive performance but not to Alzheimer disease biomarkers. Neurology. 85: 48-55. PMID 26062627 DOI: 10.1212/Wnl.0000000000001704 |
0.337 |
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| 2015 |
Amariglio RE, Mormino EC, Pietras AC, Marshall GA, Vannini P, Johnson KA, Sperling RA, Rentz DM. Subjective cognitive concerns, amyloid-β, and neurodegeneration in clinically normal elderly. Neurology. 85: 56-62. PMID 26048028 DOI: 10.1212/WNL.0000000000001712 |
0.303 |
|
| 2015 |
Marshall GA, Zoller AS, Lorius N, Amariglio RE, Locascio JJ, Johnson KA, Sperling RA, Rentz DM, For The Alzheimer's Disease Neuroimaging Initiative EY. Functional Activities Questionnaire Items that Best Discriminate and Predict Progression from Clinically Normal to Mild Cognitive Impairment. Current Alzheimer Research. 12: 493-502. PMID 26017560 |
0.383 |
|
| 2015 |
Papp KV, Amariglio RE, Mormino EC, Hedden T, Dekhytar M, Johnson KA, Sperling RA, Rentz DM. Free and cued memory in relation to biomarker-defined abnormalities in clinically normal older adults and those at risk for Alzheimer's disease. Neuropsychologia. 73: 169-75. PMID 26002757 DOI: 10.1016/j.neuropsychologia.2015.04.034 |
0.402 |
|
| 2015 |
Harkins K, Sankar P, Sperling R, Grill JD, Green RC, Johnson KA, Healy M, Karlawish J. Development of a process to disclose amyloid imaging results to cognitively normal older adult research participants. Alzheimer's Research & Therapy. 7: 26. PMID 25969699 DOI: 10.1186/S13195-015-0112-7 |
0.4 |
|
| 2015 |
Munro CE, Donovan NJ, Guercio BJ, Wigman SE, Schultz AP, Amariglio RE, Rentz DM, Johnson KA, Sperling RA, Marshall GA. Neuropsychiatric Symptoms and Functional Connectivity in Mild Cognitive Impairment. Journal of Alzheimer's Disease : Jad. PMID 25854929 DOI: 10.3233/JAD-150017 |
0.348 |
|
| 2015 |
Dagley A, LaPoint M, Huijbers W, Hedden T, McLaren DG, Chatwal JP, Papp KV, Amariglio RE, Blacker D, Rentz DM, Johnson KA, Sperling RA, Schultz AP. Harvard Aging Brain Study: Dataset and accessibility. Neuroimage. PMID 25843019 DOI: 10.1016/J.Neuroimage.2015.03.069 |
0.618 |
|
| 2015 |
Mattsson N, Insel PS, Donohue M, Jagust W, Sperling R, Aisen P, Weiner MW. Predicting Reduction of Cerebrospinal Fluid β-Amyloid 42 in Cognitively Healthy Controls. Jama Neurology. 72: 554-60. PMID 25775167 DOI: 10.1001/Jamaneurol.2014.4530 |
0.573 |
|
| 2015 |
Guercio BJ, Donovan NJ, Ward A, Schultz A, Lorius N, Amariglio RE, Rentz DM, Johnson KA, Sperling RA, Marshall GA. Apathy is associated with lower inferior temporal cortical thickness in mild cognitive impairment and normal elderly individuals. The Journal of Neuropsychiatry and Clinical Neurosciences. 27: e22-7. PMID 25716491 DOI: 10.1176/appi.neuropsych.13060141 |
0.356 |
|
| 2015 |
Perry D, Sperling R, Katz R, Berry D, Dilts D, Hanna D, Salloway S, Trojanowski JQ, Bountra C, Krams M, Luthman J, Potkin S, Gribkoff V, Temple R, Wang Y, et al. Building a roadmap for developing combination therapies for Alzheimer's disease. Expert Review of Neurotherapeutics. 15: 327-33. PMID 25708309 DOI: 10.1586/14737175.2015.996551 |
0.388 |
|
| 2015 |
Amariglio RE, Donohue MC, Marshall GA, Rentz DM, Salmon DP, Ferris SH, Karantzoulis S, Aisen PS, Sperling RA. Tracking early decline in cognitive function in older individuals at risk for Alzheimer disease dementia: the Alzheimer's Disease Cooperative Study Cognitive Function Instrument. Jama Neurology. 72: 446-54. PMID 25706191 DOI: 10.1001/Jamaneurol.2014.3375 |
0.562 |
|
| 2015 |
Donovan NJ, Hsu DC, Dagley AS, Schultz AP, Amariglio RE, Mormino EC, Okereke OI, Rentz DM, Johnson KA, Sperling RA, Marshall GA. Depressive Symptoms and Biomarkers of Alzheimer's Disease in Cognitively Normal Older Adults. Journal of Alzheimer's Disease : Jad. PMID 25697700 DOI: 10.3233/JAD-142940 |
0.315 |
|
| 2015 |
Huijbers W, Mormino EC, Schultz AP, Wigman S, Ward AM, Larvie M, Amariglio RE, Marshall GA, Rentz DM, Johnson KA, Sperling RA. Amyloid-β deposition in mild cognitive impairment is associated with increased hippocampal activity, atrophy and clinical progression. Brain : a Journal of Neurology. 138: 1023-35. PMID 25678559 DOI: 10.1093/Brain/Awv007 |
0.713 |
|
| 2015 |
Replogle JM, Chan G, White CC, Raj T, Winn PA, Evans DA, Sperling RA, Chibnik LB, Bradshaw EM, Schneider JA, Bennett DA, De Jager PL. A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology. Annals of Neurology. 77: 469-77. PMID 25545807 DOI: 10.1002/Ana.24337 |
0.375 |
|
| 2015 |
Stephenson D, Perry D, Bens C, Bain LJ, Berry D, Krams M, Sperling R, Dilts D, Luthman J, Hanna D, McKew J, Temple R, Fields FO, Salloway S, Katz R. Charting a path toward combination therapy for Alzheimer's disease. Expert Review of Neurotherapeutics. 15: 107-13. PMID 25540951 DOI: 10.1586/14737175.2015.995168 |
0.394 |
|
| 2015 |
Ward AM, Mormino EC, Huijbers W, Schultz AP, Hedden T, Sperling RA. Relationships between default-mode network connectivity, medial temporal lobe structure, and age-related memory deficits. Neurobiology of Aging. 36: 265-72. PMID 25113793 DOI: 10.1016/J.Neurobiolaging.2014.06.028 |
0.659 |
|
| 2015 |
Lorius N, Locascio JJ, Rentz DM, Johnson KA, Sperling RA, Viswanathan A, Marshall GA. Vascular disease and risk factors are associated with cognitive decline in the alzheimer disease spectrum. Alzheimer Disease and Associated Disorders. 29: 18-25. PMID 24787033 DOI: 10.1097/WAD.0000000000000043 |
0.356 |
|
| 2015 |
Toledo JB, Zetterberg H, Van Harten AC, Glodzik L, Martinez-Lage P, Bocchio-Chiavetto L, Rami L, Hansson O, Sperling R, Engelborghs S, Osorio RS, Vanderstichele H, Vandijck M, Hampel H, Teipl S, et al. Alzheimer's disease cerebrospinal fluid biomarker in cognitively normal subjects Brain. 138: 2701-2715. DOI: 10.1093/brain/awv199 |
0.495 |
|
| 2015 |
Sperling RA, Karlawish J, Grill JD, Burns JM, Sultzer D, Johnson KA, Aisen PS. F3-03-03: Disclosure of amyloid status in the a4 trial Alzheimer's & Dementia. 11: P215-P215. DOI: 10.1016/J.Jalz.2015.07.232 |
0.367 |
|
| 2015 |
Hanseeuw BJ, Schultz AP, Sperling RA, Johnson KA. P4-083: Hippocampal metabolism is decreased in high-amyloid mild cognitive impairment but not in high-amyloid clinically normal elders Alzheimer's & Dementia. 11: P802-P803. DOI: 10.1016/j.jalz.2015.06.1788 |
0.309 |
|
| 2015 |
Quiroz YT, Schultz AP, Chen K, Protas HD, Brickhouse M, Fleisher AS, Langbaum JB, Thiyyagura P, Fagan AM, Shah AR, Muniz M, Arboleda-Velasquez JF, Munoz C, Garcia G, Acosta-Baena N, ... ... Sperling RA, et al. Brain imaging and blood biomarker abnormalities in children with autosomal dominant Alzheimer disease a cross-sectional study Jama Neurology. 72: 912-919. |
0.461 |
|
| 2014 |
Cavedo E, Lista S, Khachaturian Z, Aisen P, Amouyel P, Herholz K, Jack CR, Sperling R, Cummings J, Blennow K, O'Bryant S, Frisoni GB, Khachaturian A, Kivipelto M, Klunk W, et al. The Road Ahead to Cure Alzheimer's Disease: Development of Biological Markers and Neuroimaging Methods for Prevention Trials Across all Stages and Target Populations. The Journal of Prevention of Alzheimer's Disease. 1: 181-202. PMID 26478889 DOI: 10.14283/jpad.2014.32 |
0.569 |
|
| 2014 |
Sperling R, Mormino E, Johnson K. The evolution of preclinical Alzheimer's disease: implications for prevention trials. Neuron. 84: 608-22. PMID 25442939 DOI: 10.1016/J.Neuron.2014.10.038 |
0.492 |
|
| 2014 |
Fargo KN, Aisen P, Albert M, Au R, Corrada MM, DeKosky S, Drachman D, Fillit H, Gitlin L, Haas M, Herrup K, Kawas C, Khachaturian AS, Khachaturian ZS, ... ... Sperling RA, et al. 2014 Report on the Milestones for the US National Plan to Address Alzheimer's Disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: S430-52. PMID 25341459 DOI: 10.1016/J.Jalz.2014.08.103 |
0.667 |
|
| 2014 |
Marshall GA, Zoller AS, Kelly KE, Amariglio RE, Locascio JJ, Johnson KA, Sperling RA, Rentz DM, For The Alzheimer's Disease Neuroimaging Initiative. Everyday cognition scale items that best discriminate between and predict progression from clinically normal to mild cognitive impairment. Current Alzheimer Research. 11: 853-61. PMID 25274110 |
0.324 |
|
| 2014 |
Mormino EC, Betensky RA, Hedden T, Schultz AP, Amariglio RE, Rentz DM, Johnson KA, Sperling RA. Synergistic effect of β-amyloid and neurodegeneration on cognitive decline in clinically normal individuals. Jama Neurology. 71: 1379-85. PMID 25222039 DOI: 10.1001/jamaneurol.2014.2031 |
0.31 |
|
| 2014 |
Zoller AS, Gaal IM, Royer CA, Locascio JJ, Amariglio RE, Blacker D, Okereke OI, Johnson KA, Sperling RA, Rentz DM, Marshall GA. SIST-M-IR activities of daily living items that best discriminate clinically normal elderly from those with mild cognitive impairment. Current Alzheimer Research. 11: 785-91. PMID 25212917 DOI: 10.2174/156720501108140910122220 |
0.473 |
|
| 2014 |
Schultz AP, Chhatwal JP, Huijbers W, Hedden T, van Dijk KR, McLaren DG, Ward AM, Wigman S, Sperling RA. Template based rotation: a method for functional connectivity analysis with a priori templates. Neuroimage. 102: 620-36. PMID 25150630 DOI: 10.1016/J.Neuroimage.2014.08.022 |
0.616 |
|
| 2014 |
Ryman DC, Acosta-Baena N, Aisen PS, Bird T, Danek A, Fox NC, Goate A, Frommelt P, Ghetti B, Langbaum JB, Lopera F, Martins R, Masters CL, Mayeux RP, McDade E, ... ... Sperling R, et al. Symptom onset in autosomal dominant Alzheimer disease: a systematic review and meta-analysis. Neurology. 83: 253-60. PMID 24928124 DOI: 10.1212/Wnl.0000000000000596 |
0.475 |
|
| 2014 |
Roy K, Pepin LC, Philiossaint M, Lorius N, Becker JA, Locascio JJ, Rentz DM, Sperling RA, Johnson KA, Marshall GA. Regional fluorodeoxyglucose metabolism and instrumental activities of daily living across the Alzheimer's disease spectrum. Journal of Alzheimer's Disease : Jad. 42: 291-300. PMID 24898635 DOI: 10.3233/JAD-131796 |
0.389 |
|
| 2014 |
Donohue MC, Sperling RA, Salmon DP, Rentz DM, Raman R, Thomas RG, Weiner M, Aisen PS. The preclinical Alzheimer cognitive composite: measuring amyloid-related decline. Jama Neurology. 71: 961-70. PMID 24886908 DOI: 10.1001/Jamaneurol.2014.803 |
0.539 |
|
| 2014 |
McLaren DG, Sperling RA, Atri A. Flexible modulation of network connectivity related to cognition in Alzheimer's disease. Neuroimage. 100: 544-57. PMID 24852459 DOI: 10.1016/J.Neuroimage.2014.05.032 |
0.311 |
|
| 2014 |
Papp KV, Amariglio RE, Dekhtyar M, Roy K, Wigman S, Bamfo R, Sherman J, Sperling RA, Rentz DM. Development of a psychometrically equivalent short form of the Face-Name Associative Memory Exam for use along the early Alzheimer's disease trajectory. The Clinical Neuropsychologist. 28: 771-85. PMID 24815535 DOI: 10.1080/13854046.2014.911351 |
0.373 |
|
| 2014 |
Jessen F, Amariglio RE, van Boxtel M, Breteler M, Ceccaldi M, Chételat G, Dubois B, Dufouil C, Ellis KA, van der Flier WM, Glodzik L, van Harten AC, de Leon MJ, McHugh P, Mielke MM, ... Sperling RA, et al. A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 844-52. PMID 24798886 DOI: 10.1016/J.Jalz.2014.01.001 |
0.56 |
|
| 2014 |
Mormino EC, Betensky RA, Hedden T, Schultz AP, Ward A, Huijbers W, Rentz DM, Johnson KA, Sperling RA. Amyloid and APOE ε4 interact to influence short-term decline in preclinical Alzheimer disease. Neurology. 82: 1760-7. PMID 24748674 DOI: 10.1212/Wnl.0000000000000431 |
0.712 |
|
| 2014 |
Huijbers W, Mormino EC, Wigman SE, Ward AM, Vannini P, McLaren DG, Becker JA, Schultz AP, Hedden T, Johnson KA, Sperling RA. Amyloid deposition is linked to aberrant entorhinal activity among cognitively normal older adults. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 5200-10. PMID 24719099 DOI: 10.1523/Jneurosci.3579-13.2014 |
0.729 |
|
| 2014 |
Donovan NJ, Amariglio RE, Zoller AS, Rudel RK, Gomez-Isla T, Blacker D, Hyman BT, Locascio JJ, Johnson KA, Sperling RA, Marshall GA, Rentz DM. Subjective cognitive concerns and neuropsychiatric predictors of progression to the early clinical stages of Alzheimer disease. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 22: 1642-51. PMID 24698445 DOI: 10.1016/J.Jagp.2014.02.007 |
0.355 |
|
| 2014 |
Marshall GA, Lorius N, Locascio JJ, Hyman BT, Rentz DM, Johnson KA, Sperling RA. Regional cortical thinning and cerebrospinal biomarkers predict worsening daily functioning across the Alzheimer's disease spectrum. Journal of Alzheimer's Disease : Jad. 41: 719-28. PMID 24685624 DOI: 10.3233/Jad-132768 |
0.355 |
|
| 2014 |
Sperling RA, Rentz DM, Johnson KA, Karlawish J, Donohue M, Salmon DP, Aisen P. The A4 study: stopping AD before symptoms begin? Science Translational Medicine. 6: 228fs13. PMID 24648338 DOI: 10.1126/Scitranslmed.3007941 |
0.554 |
|
| 2014 |
Doraiswamy PM, Sperling RA, Johnson K, Reiman EM, Wong TZ, Sabbagh MN, Sadowsky CH, Fleisher AS, Carpenter A, Joshi AD, Lu M, Grundman M, Mintun MA, Skovronsky DM, Pontecorvo MJ, et al. Florbetapir F 18 amyloid PET and 36-month cognitive decline: a prospective multicenter study. Molecular Psychiatry. 19: 1044-51. PMID 24614494 DOI: 10.1038/Mp.2014.9 |
0.349 |
|
| 2014 |
Fagan AM, Xiong C, Jasielec MS, Bateman RJ, Goate AM, Benzinger TL, Ghetti B, Martins RN, Masters CL, Mayeux R, Ringman JM, Rossor MN, Salloway S, Schofield PR, Sperling RA, et al. Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimer's disease. Science Translational Medicine. 6: 226ra30. PMID 24598588 DOI: 10.1126/Scitranslmed.3007901 |
0.375 |
|
| 2014 |
Serrano-Pozo A, Qian J, Monsell SE, Blacker D, Gómez-Isla T, Betensky RA, Growdon JH, Johnson KA, Frosch MP, Sperling RA, Hyman BT. Mild to moderate Alzheimer dementia with insufficient neuropathological changes. Annals of Neurology. 75: 597-601. PMID 24585367 DOI: 10.1002/Ana.24125 |
0.383 |
|
| 2014 |
Salloway S, Sperling R, Fox NC, Blennow K, Klunk W, Raskind M, Sabbagh M, Honig LS, Porsteinsson AP, Ferris S, Reichert M, Ketter N, Nejadnik B, Guenzler V, Miloslavsky M, et al. Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease. The New England Journal of Medicine. 370: 322-33. PMID 24450891 DOI: 10.1056/Nejmoa1304839 |
0.431 |
|
| 2014 |
Donovan NJ, Wadsworth LP, Lorius N, Locascio JJ, Rentz DM, Johnson KA, Sperling RA, Marshall GA. Regional cortical thinning predicts worsening apathy and hallucinations across the Alzheimer disease spectrum. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 22: 1168-79. PMID 23890751 DOI: 10.1016/j.jagp.2013.03.006 |
0.422 |
|
| 2014 |
Ward AM, Schultz AP, Huijbers W, Van Dijk KR, Hedden T, Sperling RA. The parahippocampal gyrus links the default-mode cortical network with the medial temporal lobe memory system. Human Brain Mapping. 35: 1061-73. PMID 23404748 DOI: 10.1002/Hbm.22234 |
0.649 |
|
| 2014 |
Sperling R, Mormino E, Schultz A, Rentz D, Aisen P, Johnson K. The Aging Brain - Does Amyloid Matter? Neurobiology of Aging. 35. DOI: 10.1016/J.Neurobiolaging.2014.01.111 |
0.486 |
|
| 2014 |
Johnson KA, Mormino E, Rentz DM, Schultz A, Becker JA, Sepulcre J, Chhatwal J, Amariglio R, Papp K, Marshall G, Shoup T, Yokell D, Brady T, Hyman B, Vasdev N, Sperling R, et al. DT-01-02: TEMPORAL NEOCORTICAL TAU DEPOSITION MEASURED WITH PET IS ASSOCIATED WITH LONGITUDINAL DECLINE IN MEMORY PERFORMANCE AMONG CLINICALLY NORMAL ELDERLY Alzheimer's & Dementia. 10: P280-P280. DOI: 10.1016/J.Jalz.2014.07.150 |
0.529 |
|
| 2014 |
Marshall G, Dekhtyar M, Bruno J, Roy K, Masters C, Jethwani K, Amariglio RE, Johnson K, Sperling R, Rentz DM. A New Performance-Based Activities Of Daily Living Instrument For Early Alzheimer'S Disease Alzheimers & Dementia. 10: 365. DOI: 10.1016/J.Jalz.2014.05.418 |
0.4 |
|
| 2014 |
Margolin R, Di J, Andrews R, Salloway S, Sperling R, Brashear HR, Liu E, Schmidt M, Matthews DC. Amyloid Burden-Related Performance Differences On Cognitive And Functional Instruments Across Alzheimer'S Disease Pathophysiologic Stages Alzheimers & Dementia. 10: 839. DOI: 10.1016/J.Jalz.2014.05.1656 |
0.478 |
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| 2014 |
Growdon M, Schultz A, Dagley A, Amariglio RE, Hedden T, Rentz DM, Johnson K, Sperling R, Albers MW, Marshall G. Olfactory Identification And Alzheimer'S Disease Biomarkers In Clinically Normal Elderly Alzheimers & Dementia. 10: 87. DOI: 10.1016/J.Jalz.2014.05.159 |
0.393 |
|
| 2014 |
Munro CE, Donovan NJ, Guercio B, Wigman SE, Schultz A, Amariglio RE, Rentz DM, Johnson K, Sperling R, Marshall G. Neuropsychiatric Symptoms And Functional Connectivity In Mild Cognitive Impairment And Cognitively Normal Elderly Alzheimers & Dementia. 10: 729. DOI: 10.1016/J.Jalz.2014.05.1358 |
0.35 |
|
| 2014 |
Johnson KA, Schultz A, Becker A, Hyman B, Rentz D, Sepulcre J, Vasdev N, Sperling R, Brady T. Tau Pet Using F18-T807: Initial Experience In Normal Elderly And Ad Dementia Alzheimers & Dementia. 10: 242. DOI: 10.1016/J.Jalz.2014.04.365 |
0.376 |
|
| 2014 |
Huijbers W, Mormino E, Schultz A, Chhatwal J, Boot BP, Amariglio RE, Marshall G, Rentz DM, Johnson KA, Sperling R. O3-10-06: AMYLOID-β DEPOSITION IN MILD COGNITIVE IMPAIRMENT IS ASSOCIATED WITH HIPPOCAMPAL HYPERACTIVATION, ATROPHY, AND CLINICAL PROGRESSION Alzheimer's & Dementia. 10: P230-P230. DOI: 10.1016/J.Jalz.2014.04.328 |
0.638 |
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| 2014 |
Sepulcre J, Johnson KA, Sperling R. F2-02-03: TAU AND AB DEPOSITS RELATE TO DISTINCTIVE FUNCTIONAL CONNECTIVITY DISRUPTIONS IN THE ELDERLY BRAIN Alzheimer's & Dementia. 10: P159-P160. DOI: 10.1016/J.Jalz.2014.04.143 |
0.317 |
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| 2013 |
Rentz DM, Parra Rodriguez MA, Amariglio R, Stern Y, Sperling R, Ferris S. Promising developments in neuropsychological approaches for the detection of preclinical Alzheimer's disease: a selective review. Alzheimer's Research & Therapy. 5: 58. PMID 24257331 DOI: 10.1186/Alzrt222 |
0.433 |
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| 2013 |
Marshall GA, Donovan NJ, Lorius N, Gidicsin CM, Maye J, Pepin LC, Becker JA, Amariglio RE, Rentz DM, Sperling RA, Johnson KA. Apathy is associated with increased amyloid burden in mild cognitive impairment. The Journal of Neuropsychiatry and Clinical Neurosciences. 25: 302-7. PMID 24247857 DOI: 10.1176/Appi.Neuropsych.12060156 |
0.361 |
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| 2013 |
Benzinger TL, Blazey T, Jack CR, Koeppe RA, Su Y, Xiong C, Raichle ME, Snyder AZ, Ances BM, Bateman RJ, Cairns NJ, Fagan AM, Goate A, Marcus DS, Aisen PS, ... ... Sperling RA, et al. Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 110: E4502-9. PMID 24194552 DOI: 10.1073/Pnas.1317918110 |
0.489 |
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| 2013 |
Santiago JA, Scherzer CR, Potashkin JA, Hyman BT, Ivinson AJ, Trisini-Lipsanopoulos A, Dhima K, Bayer S, Lockhart KC, Yi T, Liao Z, Hoesing AN, Duong K, Roderick S, Sudarsky LR, ... ... Sperling R, et al. Specific splice variants are associated with Parkinson's disease Movement Disorders. 28: 1724-1727. PMID 24108702 DOI: 10.1002/mds.25635 |
0.366 |
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| 2013 |
Mills SM, Mallmann J, Santacruz AM, Fuqua A, Carril M, Aisen PS, Althage MC, Belyew S, Benzinger TL, Brooks WS, Buckles VD, Cairns NJ, Clifford D, Danek A, Fagan AM, ... ... Sperling RA, et al. Preclinical trials in autosomal dominant AD: implementation of the DIAN-TU trial. Revue Neurologique. 169: 737-43. PMID 24016464 DOI: 10.1016/J.Neurol.2013.07.017 |
0.481 |
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| 2013 |
Salmon DP, Ferris SH, Thomas RG, Sano M, Cummings JL, Sperling RA, Petersen RC, Aisen PS. Age and apolipoprotein E genotype influence rate of cognitive decline in nondemented elderly. Neuropsychology. 27: 391-401. PMID 23876113 DOI: 10.1037/A0032707 |
0.539 |
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| 2013 |
Vellas B, Carrillo MC, Sampaio C, Brashear HR, Siemers E, Hampel H, Schneider LS, Weiner M, Doody R, Khachaturian Z, Cedarbaum J, Grundman M, Broich K, Giacobini E, Dubois B, ... Sperling R, et al. Designing drug trials for Alzheimer's disease: what we have learned from the release of the phase III antibody trials: a report from the EU/US/CTAD Task Force. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 438-44. PMID 23809364 DOI: 10.1016/J.Jalz.2013.03.007 |
0.551 |
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| 2013 |
Sepulcre J, Sabuncu MR, Becker A, Sperling R, Johnson KA. In vivo characterization of the early states of the amyloid-beta network. Brain : a Journal of Neurology. 136: 2239-52. PMID 23801740 DOI: 10.1093/Brain/Awt146 |
0.489 |
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| 2013 |
Sperling R, Johnson K. Biomarkers of Alzheimer disease: current and future applications to diagnostic criteria. Continuum (Minneapolis, Minn.). 19: 325-38. PMID 23558480 DOI: 10.1212/01.CON.0000429181.60095.99 |
0.381 |
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| 2013 |
Werring DJ, Sperling R. Inflammatory cerebral amyloid angiopathy and amyloid-modifying therapies: variations on the same ARIA? Annals of Neurology. 73: 439-41. PMID 23526685 DOI: 10.1002/Ana.23891 |
0.32 |
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| 2013 |
Carrillo MC, Brashear HR, Logovinsky V, Ryan JM, Feldman HH, Siemers ER, Abushakra S, Hartley DM, Petersen RC, Khachaturian AS, Sperling RA. Can we prevent Alzheimer's disease? Secondary "prevention" trials in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 123-131.e1. PMID 23411394 DOI: 10.1016/J.Jalz.2012.12.004 |
0.367 |
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| 2013 |
Huijbers W, Schultz AP, Vannini P, McLaren DG, Wigman SE, Ward AM, Hedden T, Sperling RA. The encoding/retrieval flip: interactions between memory performance and memory stage and relationship to intrinsic cortical networks. Journal of Cognitive Neuroscience. 25: 1163-79. PMID 23384193 DOI: 10.1162/Jocn_A_00366 |
0.65 |
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| 2013 |
Yang T, Hong S, O'Malley T, Sperling RA, Walsh DM, Selkoe DJ. New ELISAs with high specificity for soluble oligomers of amyloid β-protein detect natural Aβ oligomers in human brain but not CSF. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 99-112. PMID 23375565 DOI: 10.1016/J.Jalz.2012.11.005 |
0.477 |
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| 2013 |
Johnson KA, Sperling RA, Gidicsin CM, Carmasin JS, Maye JE, Coleman RE, Reiman EM, Sabbagh MN, Sadowsky CH, Fleisher AS, Murali Doraiswamy P, Carpenter AP, Clark CM, Joshi AD, Lu M, et al. Florbetapir (F18-AV-45) PET to assess amyloid burden in Alzheimer's disease dementia, mild cognitive impairment, and normal aging. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: S72-83. PMID 23375563 DOI: 10.1016/J.Jalz.2012.10.007 |
0.375 |
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| 2013 |
Sperling RA, Karlawish J, Johnson KA. Preclinical Alzheimer disease-the challenges ahead. Nature Reviews. Neurology. 9: 54-8. PMID 23183885 DOI: 10.1038/nrneurol.2012.241 |
0.34 |
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| 2013 |
Quiroz YT, Stern CE, Reiman EM, Brickhouse M, Ruiz A, Sperling RA, Lopera F, Dickerson BC. Cortical atrophy in presymptomatic Alzheimer's disease presenilin 1 mutation carriers. Journal of Neurology, Neurosurgery, and Psychiatry. 84: 556-61. PMID 23134660 DOI: 10.1136/Jnnp-2012-303299 |
0.585 |
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| 2013 |
Desikan RS, McEvoy LK, Holland D, Thompson WK, Brewer JB, Aisen PS, Andreassen OA, Hyman BT, Sperling RA, Dale AM. Apolipoprotein E epsilon4 does not modulate amyloid-β-associated neurodegeneration in preclinical Alzheimer disease. Ajnr. American Journal of Neuroradiology. 34: 505-10. PMID 22976236 DOI: 10.3174/Ajnr.A3267 |
0.534 |
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| 2013 |
Sperling RA, Johnson KA, Doraiswamy PM, Reiman EM, Fleisher AS, Sabbagh MN, Sadowsky CH, Carpenter A, Davis MD, Lu M, Flitter M, Joshi AD, Clark CM, Grundman M, Mintun MA, et al. Amyloid deposition detected with florbetapir F 18 ((18)F-AV-45) is related to lower episodic memory performance in clinically normal older individuals. Neurobiology of Aging. 34: 822-31. PMID 22878163 DOI: 10.1016/j.neurobiolaging.2012.06.014 |
0.316 |
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| 2013 |
Fleisher AS, Chen K, Liu X, Ayutyanont N, Roontiva A, Thiyyagura P, Protas H, Joshi AD, Sabbagh M, Sadowsky CH, Sperling RA, Clark CM, Mintun MA, Pontecorvo MJ, Coleman RE, et al. Apolipoprotein E ε4 and age effects on florbetapir positron emission tomography in healthy aging and Alzheimer disease. Neurobiology of Aging. 34: 1-12. PMID 22633529 DOI: 10.1016/J.Neurobiolaging.2012.04.017 |
0.312 |
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| 2013 |
Vannini P, Hedden T, Huijbers W, Ward A, Johnson KA, Sperling RA. The ups and downs of the posteromedial cortex: age- and amyloid-related functional alterations of the encoding/retrieval flip in cognitively normal older adults. Cerebral Cortex (New York, N.Y. : 1991). 23: 1317-28. PMID 22586140 DOI: 10.1093/Cercor/Bhs108 |
0.733 |
|
| 2013 |
Mills S, Mallmann J, Santacruz A, Fuqua A, Carril M, Aisen P, Althage M, Belyew S, Benzinger T, Brooks W, Buckles V, Cairns N, Clifford D, Danek A, Fagan A, ... ... Sperling R, et al. Erratum to “Preclinical trials in autosomal dominant AD: Implementation of the DIAN-TU trial” [Rev. Neurol. 169 (10) (2013) 737–743] Revue Neurologique. 169: 1018. DOI: 10.1016/J.Neurol.2013.10.005 |
0.467 |
|
| 2013 |
Salloway S, Sperling R, Gregg K, Yu P, Joshi A, Lu M, Mintun M, Pontecorvo M, Booth K, Wyman B, Sun J, Sundell K, Schmidt M, Margolin R, Skovronsky D, et al. Incidence and clinical progression of placebo-treated amyloid-negative subjects with mild-to-moderate Alzheimer's disease (AD): Results from the phase III PET substudies of bapineuzumab and solanezumab Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.08.250 |
0.471 |
|
| 2013 |
Papp K, Amariglio R, Sperling R, Bamfo R, Wigman S, Rentz D. P2-273: Semantic memory and its relationship to episodic memory and amyloid burden in cognitively normal (CN) older adults and those with mild cognitive impairment (MCI) Alzheimer's & Dementia. 9: P457-P458. DOI: 10.1016/J.Jalz.2013.05.920 |
0.434 |
|
| 2013 |
Donovan N, Zoller A, Rudel R, Amariglio R, Locascio J, Johnson K, Sperling R, Marshall G, Rentz D. Neuropsychiatric and cognitive factors predict progression to mild cognitive impairment and dementia Alzheimers & Dementia. 9: 443. DOI: 10.1016/J.Jalz.2013.05.884 |
0.378 |
|
| 2013 |
Romano S, Potkin S, Barlas S, Sperling R, Kalali A, Siemers E, Logovinsky V. Designing the next generation of disease modification trials in people with early Alzheimer's disease: Learnings from recently completed programs in mild-to-moderate populations Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.05.625 |
0.349 |
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| 2013 |
Einstein S, Bouix S, Nielsen C, Clegg S, Les A, Simon H, Hill D, Margolin R, Sperling R, Fox N, Liu E, Novak G. The impact of gradient field distortion on the calculation of brain atrophy in Alzheimer's disease, derived from volumetric MRI using the boundary shift integral Alzheimers & Dementia. 9: 105. DOI: 10.1016/J.Jalz.2013.05.561 |
0.343 |
|
| 2013 |
Langbaum J, High N, Aisen P, Albert M, Brown K, Comer M, Cummings J, Manly J, Petersen R, Sperling R, Strobel G, Weiner M, Tariot P, Reiman E. Development and implementation of the National Alzheimer's Prevention Registry Alzheimers & Dementia. 9: 280. DOI: 10.1016/J.Jalz.2013.05.560 |
0.614 |
|
| 2013 |
Vannini P, Wigman S, Ward A, Amariglio R, Marshall G, Schultz A, Dijk Kv, Huijbers W, Rentz D, Johnson K, Sperling R. Decreased resting state functional connectivity at baseline predicts subjective memory complaints after 1 year in cognitively normal individuals and individuals with mild cognitive impairment Alzheimers & Dementia. 9: 110. DOI: 10.1016/J.Jalz.2013.05.195 |
0.698 |
|
| 2013 |
Ward A, Mormino E, Schultz A, Hedden T, Johnson K, Sperling R. IC-P-188: Entorhinal thickness mediates the relationship between hippocampus volume and default-mode network connectivity independently of amyloid burden in cognitively intact elderly Alzheimer's & Dementia. 9: P106-P107. DOI: 10.1016/J.Jalz.2013.05.187 |
0.377 |
|
| 2013 |
Marshall G, Zoller A, Lorius N, Amariglio R, Locascio J, Johnson K, Sperling R, Rentz D. Functional activities questionnaire items that best predict disease progression in the clinically normal elderly Alzheimers & Dementia. 9: 779. DOI: 10.1016/J.Jalz.2013.05.1590 |
0.34 |
|
| 2013 |
Sepulcre J, Becker J, Sperling R, Johnson K. Amyloid hubs in individual PiB-PET imaging Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.05.1156 |
0.312 |
|
| 2013 |
Blazey T, Jack C, Kantarci K, Preboske G, Ringman J, Brickman A, Raichle M, Hornbeck R, Saykin A, Salloway S, McDade E, Rossor M, Fox N, Thompson P, Correia S, ... ... Sperling R, et al. Prevalence and growth of cerebral microhemorrhages in autosomal dominant Alzheimer's disease Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.05.100 |
0.366 |
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| 2013 |
Schultz A, McLaren D, Chhatwal J, Evans K, Johnson K, Sperling R. IC-P-101: Increased cerebral blood flow in cognitively normal older adults with amyloid Alzheimer's & Dementia. 9: P58-P59. DOI: 10.1016/J.Jalz.2013.05.098 |
0.348 |
|
| 2013 |
Chhatwal J, Schultz A, Johnson K, Benzinger T, Jack C, Ances B, Sullivan C, Salloway S, Ringman J, Koeppe R, Marcus D, Thompson P, Saykin A, Correia S, Schofield P, ... ... Sperling R, et al. IC-P-082: Disrupted functional connectivity in autosomal dominant Alzheimer's disease demonstrates network specificity and precedes brain volume loss: Findings from DIAN Alzheimer's & Dementia. 9: P49-P50. DOI: 10.1016/J.Jalz.2013.05.079 |
0.381 |
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| 2013 |
Wigman S, Mormino E, Schultz A, Ward A, Amariglio R, Huijbers W, Rentz D, Johnson K, Sperling R, Vannini P. IC-P-081: Differential anatomical correlates of objective and subjective memory in older individuals across a spectrum of memory impairment Alzheimer's & Dementia. 9: P49-P49. DOI: 10.1016/J.Jalz.2013.05.078 |
0.677 |
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| 2013 |
Cash D, Ridgway G, Modat M, Ryan N, Kinnunen K, Cardoso J, Benzinger T, Jack CR, Raichle M, Marcus D, Ringman J, Thompson P, Ghetti B, Salloway S, Sperling R, et al. Dissociating volume and intensity differences in familial Alzheimer's disease Alzheimers & Dementia. 9: 603. DOI: 10.1016/J.Jalz.2013.05.075 |
0.361 |
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| 2013 |
Huijbers W, Ward A, Wigman S, Mormino E, Vannini P, Becker J, Schultz A, Johnson K, Hedden T, Sperling R. IC-P-013: Dissociations between entorhinal and hippocampal activity in cognitively normal older adults with and without beta-amyloid deposition Alzheimer's & Dementia. 9: P17-P17. DOI: 10.1016/J.Jalz.2013.05.014 |
0.696 |
|
| 2013 |
Chhatwal J, Schultz A, Johnson K, Benzinger T, Jack C, Ances B, Sullivan C, Salloway S, Ringman J, Koeppe R, Marcus D, Thompson P, Saykin A, Correia S, Schofield P, ... ... Sperling R, et al. O4-03-03: Disrupted functional connectivity in autosomal dominant Alzheimer's disease demonstrates network specificity and precedes brain volume loss: Findings from the Dominantly Inherited Alzheimer Network Alzheimer's & Dementia. 9: P684-P685. DOI: 10.1016/J.Jalz.2013.04.348 |
0.384 |
|
| 2013 |
Becker J, Rentz D, Pepin L, Sperling R, Johnson K. Amyloid, apolipoprotein E (APOE) and age in relation to longitudinal FDG metabolism and clinical decline in cognitively normal and mildly impaired elderly Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.04.143 |
0.41 |
|
| 2013 |
Sperling R. Functional MRI as a marker of memory network disruption in early Alzheimer's disease Alzheimers & Dementia. 9: 313. DOI: 10.1016/J.Jalz.2013.04.130 |
0.427 |
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| 2013 |
Mormino E, Vannini P, Amariglio R, Schultz A, Marshall G, Johnson K, Sperling R, Rentz D. O1-04-04: Subjective cognitive concerns, amyloid burden and cognitive reserve Alzheimer's & Dementia. 9: P133-P134. DOI: 10.1016/J.Jalz.2013.04.070 |
0.37 |
|
| 2013 |
Rentz D, Hedden T, Mormino E, Amariglio R, Becker J, Schultz A, Marshall G, Sperling R, Johnson K. IC-O2-02: Detecting cognitive evidence of preclinical Alzheimer's disease Alzheimer's & Dementia. 9: P6-P6. DOI: 10.1016/J.Jalz.2013.04.022 |
0.403 |
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| 2013 |
Kinnunen K, Ryan N, Cash D, Leite AB, Finnegan S, Cardoso M, Leung K, Modat M, Benzinger T, Jack C, Marcus D, Raichle M, Thompson P, Ringman J, Ghetti B, ... ... Sperling R, et al. Are early atrophy patterns in autosomal dominant familial Alzheimer's disease gene-dependent? Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.04.017 |
0.347 |
|
| 2013 |
Sperling R. Sowing the seeds of hope: The potential to slow disease now and prevent dementia in the future Alzheimers & Dementia. 9: 1. DOI: 10.1016/J.Jalz.2013.04.010 |
0.356 |
|
| 2012 |
Marshall GA, Amariglio RE, Sperling RA, Rentz DM. Activities of daily living: where do they fit in the diagnosis of Alzheimer's disease? Neurodegenerative Disease Management. 2: 483-491. PMID 23585777 DOI: 10.2217/nmt.12.55 |
0.405 |
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| 2012 |
Hedden T, Mormino EC, Amariglio RE, Younger AP, Schultz AP, Becker JA, Buckner RL, Johnson KA, Sperling RA, Rentz DM. Cognitive profile of amyloid burden and white matter hyperintensities in cognitively normal older adults. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 16233-42. PMID 23152607 DOI: 10.1523/JNEUROSCI.2462-12.2012 |
0.339 |
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| 2012 |
Morris JC, Aisen PS, Bateman RJ, Benzinger TL, Cairns NJ, Fagan AM, Ghetti B, Goate AM, Holtzman DM, Klunk WE, McDade E, Marcus DS, Martins RN, Masters CL, Mayeux R, ... Sperling RA, et al. Developing an international network for Alzheimer research: The Dominantly Inherited Alzheimer Network. Clinical Investigation. 2: 975-984. PMID 23139856 DOI: 10.4155/Cli.12.93 |
0.537 |
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| 2012 |
Reiman EM, Quiroz YT, Fleisher AS, Chen K, Velez-Pardo C, Jimenez-Del-Rio M, Fagan AM, Shah AR, Alvarez S, Arbelaez A, Giraldo M, Acosta-Baena N, Sperling RA, Dickerson B, Stern CE, et al. Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study. The Lancet. Neurology. 11: 1048-56. PMID 23137948 DOI: 10.1016/S1474-4422(12)70228-4 |
0.579 |
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| 2012 |
Huijbers W, Vannini P, Sperling RA, C M P, Cabeza R, Daselaar SM. Explaining the encoding/retrieval flip: memory-related deactivations and activations in the posteromedial cortex. Neuropsychologia. 50: 3764-74. PMID 22982484 DOI: 10.1016/J.Neuropsychologia.2012.08.021 |
0.804 |
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| 2012 |
Amariglio RE, Becker JA, Carmasin J, Wadsworth LP, Lorius N, Sullivan C, Maye JE, Gidicsin C, Pepin LC, Sperling RA, Johnson KA, Rentz DM. Subjective cognitive complaints and amyloid burden in cognitively normal older individuals. Neuropsychologia. 50: 2880-6. PMID 22940426 DOI: 10.1016/J.Neuropsychologia.2012.08.011 |
0.377 |
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| 2012 |
Wadsworth LP, Lorius N, Donovan NJ, Locascio JJ, Rentz DM, Johnson KA, Sperling RA, Marshall GA. Neuropsychiatric symptoms and global functional impairment along the Alzheimer's continuum. Dementia and Geriatric Cognitive Disorders. 34: 96-111. PMID 22922821 DOI: 10.1159/000342119 |
0.37 |
|
| 2012 |
Chhatwal JP, Sperling RA. Functional MRI of mnemonic networks across the spectrum of normal aging, mild cognitive impairment, and Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 31: S155-67. PMID 22890098 DOI: 10.3233/Jad-2012-120730 |
0.34 |
|
| 2012 |
Doraiswamy PM, Sperling RA, Coleman RE, Johnson KA, Reiman EM, Davis MD, Grundman M, Sabbagh MN, Sadowsky CH, Fleisher AS, Carpenter A, Clark CM, Joshi AD, Mintun MA, Skovronsky DM, et al. Amyloid-β assessed by florbetapir F 18 PET and 18-month cognitive decline: a multicenter study. Neurology. 79: 1636-44. PMID 22786606 DOI: 10.1212/Wnl.0B013E3182661F74 |
0.378 |
|
| 2012 |
Bateman RJ, Xiong C, Benzinger TL, Fagan AM, Goate A, Fox NC, Marcus DS, Cairns NJ, Xie X, Blazey TM, Holtzman DM, Santacruz A, Buckles V, Oliver A, Moulder K, ... Sperling RA, et al. Clinical and biomarker changes in dominantly inherited Alzheimer's disease. The New England Journal of Medicine. 367: 795-804. PMID 22784036 DOI: 10.1056/Nejmoa1202753 |
0.528 |
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| 2012 |
Amariglio RE, Frishe K, Olson LE, Wadsworth LP, Lorius N, Sperling RA, Rentz DM. Validation of the Face Name Associative Memory Exam in cognitively normal older individuals. Journal of Clinical and Experimental Neuropsychology. 34: 580-7. PMID 22765048 DOI: 10.1080/13803395.2012.666230 |
0.316 |
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| 2012 |
Desikan RS, McEvoy LK, Thompson WK, Holland D, Brewer JB, Aisen PS, Sperling RA, Dale AM. Amyloid-β--associated clinical decline occurs only in the presence of elevated P-tau. Archives of Neurology. 69: 709-13. PMID 22529247 DOI: 10.1001/Archneurol.2011.3354 |
0.547 |
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| 2012 |
McLaren DG, Sreenivasan A, Diamond EL, Mitchell MB, Van Dijk KR, Deluca AN, O'Brien JL, Rentz DM, Sperling RA, Atri A. Tracking cognitive change over 24 weeks with longitudinal functional magnetic resonance imaging in Alzheimer's disease. Neuro-Degenerative Diseases. 9: 176-86. PMID 22456451 DOI: 10.1159/000335876 |
0.375 |
|
| 2012 |
Bakken TE, Roddey JC, Djurovic S, Akshoomoff N, Amaral DG, Bloss CS, Casey BJ, Chang L, Ernst TM, Gruen JR, Jernigan TL, Kaufmann WE, Kenet T, Kennedy DN, Kuperman JM, ... ... Sperling RA, et al. Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans. Proceedings of the National Academy of Sciences of the United States of America. 109: 3985-90. PMID 22343285 DOI: 10.1073/Pnas.1105829109 |
0.731 |
|
| 2012 |
Sperling R, Salloway S, Brooks DJ, Tampieri D, Barakos J, Fox NC, Raskind M, Sabbagh M, Honig LS, Porsteinsson AP, Lieberburg I, Arrighi HM, Morris KA, Lu Y, Liu E, et al. Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis. The Lancet. Neurology. 11: 241-9. PMID 22305802 DOI: 10.1016/S1474-4422(12)70015-7 |
0.339 |
|
| 2012 |
Villemagne VL, Klunk WE, Mathis CA, Rowe CC, Brooks DJ, Hyman BT, Ikonomovic MD, Ishii K, Jack CR, Jagust WJ, Johnson KA, Koeppe RA, Lowe VJ, Masters CL, Montine TJ, ... ... Sperling RA, et al. Aβ Imaging: feasible, pertinent, and vital to progress in Alzheimer's disease. European Journal of Nuclear Medicine and Molecular Imaging. 39: 209-19. PMID 22218879 DOI: 10.1007/S00259-011-2045-0 |
0.488 |
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| 2012 |
Sabuncu MR, Buckner RL, Smoller JW, Lee PH, Fischl B, Sperling RA. The association between a polygenic Alzheimer score and cortical thickness in clinically normal subjects. Cerebral Cortex (New York, N.Y. : 1991). 22: 2653-61. PMID 22169231 DOI: 10.1093/Cercor/Bhr348 |
0.366 |
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| 2012 |
Vannini P, Hedden T, Becker JA, Sullivan C, Putcha D, Rentz D, Johnson KA, Sperling RA. Age and amyloid-related alterations in default network habituation to stimulus repetition. Neurobiology of Aging. 33: 1237-52. PMID 21334099 DOI: 10.1016/j.neurobiolaging.2011.01.003 |
0.393 |
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| 2012 |
Marshall G, Lorius N, Gidicsin C, Maye J, Becker JA, Amariglio R, Rentz D, Sperling R, Johnson K. Instrumental Activities of Daily Living Impairment Is Associated with Temporal and Parietal Hypometabolism in Mild Cognitive Impairment (P04.214) Neurology. 78: P04.214-P04.214. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P04.214 |
0.385 |
|
| 2012 |
Salloway S, Sperling R, Porsteinsson A, Crans G, Hernandez C, Abushakra S. Responder Analyses from a 78-Week Phase 2 Placebo-Controlled Study of ELND005 (Scyllo-Inositol) in Mild to Moderate (MM) Alzheimer's Disease (AD) (P04.195) Neurology. 78: P04.195-P04.195. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P04.195 |
0.331 |
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| 2012 |
Porsteinsson A, Sperling R, Salloway S, Crans G, Hernandez C, Abushakra S. Responders to ELND005 (Scyllo-Inositol) Demonstrate Clinical and Biomarker Characteristics Consistent with Mild Alzheimer's Disease (AD): Data from a 78-Week Phase 2 Study in Mild to Moderate (M/M) AD (P04.194) Neurology. 78: P04.194-P04.194. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P04.194 |
0.416 |
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| 2012 |
Mckhann GM, Albert MS, Sperling RA. Changing diagnostic concepts of Alzheimer's disease Advances in Biological Psychiatry. 28: 115-121. DOI: 10.1159/000335402 |
0.472 |
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| 2012 |
Schneider JA, Montine TJ, Sperling RA, Bennett DA. Neuropathological basis of Alzheimer's disease and Alzheimer's disease diagnosis Advances in Biological Psychiatry. 28: 49-70. DOI: 10.1159/000335384 |
0.304 |
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| 2012 |
Sperling R, Downing AC, Salmon D, Rentz D, Siemers E, Sethuraman G, Karlawish J, Johnson K, Donohue M, Aisen P. The A4 trial: Anti-amyloid treatment of asymptomatic Alzheimer's disease Alzheimers & Dementia. 10: 246. DOI: 10.1016/J.Jalz.2014.04.378 |
0.534 |
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| 2012 |
Doraiswamy PM, Sperling R, Coleman E, Johnson K, Fleisher A, Reiman E, Sabbagh M, Sadowsky C, Joshi A, Lu M, Mintun M, Skovronsky D, Pontecorvo M. Prognostic significance of Florbetapir (18F-Florbetapir) PET imaging for future cognitive performance in recently diagnosed MCI: Final results from a 3-year multicenter longitudinal trial Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2013.08.063 |
0.34 |
|
| 2012 |
Becker J, Koeppe R, Benzinger T, Jack C, Marcus D, Raichle M, Thompson P, Saykin A, Correia S, Schofield P, Rowe C, Fox N, Brickman A, Ghetti B, Masters C, ... ... Sperling R, et al. FDG metabolism in the DIAN study of autosomal dominant Alzheimer's disease Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.655 |
0.377 |
|
| 2012 |
Chhatwal J, Schultz A, Johnson K, Benzinger T, Jack C, Salloway S, Ringman J, Koeppe R, Marcus D, Thompson P, Saykin A, Correia S, Schofield P, Rowe C, Fox N, ... ... Sperling R, et al. O2-06-01: Disrupted functional connectivity in autosomal dominant Alzheimer's disease: Preliminary findings from the DIAN study Alzheimer's & Dementia. 8: P244-P245. DOI: 10.1016/J.Jalz.2012.05.654 |
0.383 |
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| 2012 |
Sperling R, Roberts S. Disclosure of amyloid status in secondary prevention trials for Alzheimer's disease Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.2120 |
0.448 |
|
| 2012 |
Benzinger T, Blazey T, Ances B, Raichle M, Ances B, Snyder A, Su Y, Marcus D, Ringman J, Thompson P, Ghetti B, Saykin A, Salloway S, Correia S, Johnson K, ... Sperling R, et al. IC-P-128: Progressive white matter abnormalities in autosomal dominant Alzheimer's disease: Results of the DIAN study Alzheimer's & Dementia. 8: P68-P69. DOI: 10.1016/j.jalz.2012.05.1858 |
0.371 |
|
| 2012 |
Kinnunen K, Cash D, Leung K, Liang Y, Cardoso M, Modat M, Malone I, Benzinger T, Koeppe R, Jack C, Raichle M, Marcus D, Ringman J, Thompson P, Saykin A, ... ... Sperling R, et al. Brain and hippocampal rates of atrophy in familial Alzheimer's disease mutation carriers: Preliminary findings from the DIAN study Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.172 |
0.357 |
|
| 2012 |
Sperling R. Amyloid-Related Imaging Abnormalities (ARIA) Alzheimers & Dementia. 8: 606. DOI: 10.1016/J.Jalz.2012.05.1624 |
0.321 |
|
| 2012 |
Benzinger T, Blazey T, Koeppe R, Jack C, Raichle M, Su Y, Snyder A, Marcus D, Ringman J, Thompson P, Ghetti B, Saykin A, Salloway S, Correia S, Johnson K, Sperling R, et al. Elevated PiB precedes dementia in autosomal dominant Alzheimer's disease: PiB, FDG and atrophy in the DIAN cohort Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.132 |
0.457 |
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| 2012 |
Mormino E, Schultz A, Becker J, Gidicsin C, Pepin L, Rentz D, Maye J, Amariglio R, Marshall G, Sperling R, Johnson K. Evidence for dissociable patterns of PiB retention during early stages of amyloid accumulation Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.108 |
0.304 |
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| 2012 |
Donovan N, Wadsworth L, Lorius N, Locascio J, Rentz D, Johnson K, Sperling R, Marshall G. Regional cortical thinning predicts worsening apathy and hallucinations in mild cognitive impairment and mild Alzheimer's disease Alzheimers & Dementia. 8: 26. DOI: 10.1016/J.Jalz.2012.05.071 |
0.462 |
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| 2012 |
Kinnunen K, Cash D, Liang Y, Leung K, Cardoso M, Modat M, Malone I, Yeatman T, Nicholas J, Benzinger T, Koeppe R, Jack C, Raichle M, Marcus D, Ringman J, ... ... Sperling R, et al. Cross-sectional cerebral volumetric differences and associations with estimated time to age-at-onset in familial Alzheimer's disease: Findings from the DIAN study Alzheimers & Dementia. 8: 23. DOI: 10.1016/J.Jalz.2012.05.064 |
0.436 |
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| 2012 |
McLaren D, Sperling R, Atri A. A biomarker signal: Context-dependent hippocampal fMRI connectivity analysis of clinical trial measures in Alzheimer's disease Alzheimers & Dementia. 8: 19. DOI: 10.1016/J.Jalz.2012.05.054 |
0.406 |
|
| 2012 |
Cash D, Ridgway G, Ryan N, Kinnunen K, Yeatman T, Malone I, Benzinger T, Koeppe R, Jack C, Raichle M, Marcus D, Ringman J, Thompson P, Saykin A, Salloway S, ... ... Sperling R, et al. A voxel-based morphometry study of volumetric MRI in familial Alzheimer’s disease Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.052 |
0.367 |
|
| 2012 |
Bateman R, Benzinger T, Cairns N, Fagan A, Goate A, Marcus D, Storandt M, Xiong C, Buckles V, Holtzman D, Moulder K, Oliver A, Santacruz A, Fox N, Ghetti B, ... ... Sperling R, et al. Presymptomatic Alzheimer's disease in the Dominantly Inherited Alzheimer's Network (DIAN) Alzheimers & Dementia. 8: 4. DOI: 10.1016/J.Jalz.2012.05.015 |
0.421 |
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| 2011 |
Silverberg NB, Ryan LM, Carrillo MC, Sperling R, Petersen RC, Posner HB, Snyder PJ, Hilsabeck R, Gallagher M, Raber J, Rizzo A, Possin K, King J, Kaye J, Ott BR, et al. Assessment of cognition in early dementia. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: e60-e76. PMID 23559893 DOI: 10.1016/J.Jalz.2011.05.001 |
0.609 |
|
| 2011 |
Reiman EM, McKhann GM, Albert MS, Sperling RA, Petersen RC, Blacker D. Clinical impact of updated diagnostic and research criteria for Alzheimer's disease. The Journal of Clinical Psychiatry. 72: e37. PMID 22244033 DOI: 10.4088/Jcp.10087Tx2C |
0.533 |
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| 2011 |
Holtzman DM, Goate A, Kelly J, Sperling R. Mapping the road forward in Alzheimer's disease. Science Translational Medicine. 3: 114ps48. PMID 22190237 DOI: 10.1126/Scitranslmed.3003529 |
0.458 |
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| 2011 |
Sperling RA, Jack CR, Aisen PS. Testing the right target and right drug at the right stage. Science Translational Medicine. 3: 111cm33. PMID 22133718 DOI: 10.1126/Scitranslmed.3002609 |
0.492 |
|
| 2011 |
Putcha D, Brickhouse M, O'Keefe K, Sullivan C, Rentz D, Marshall G, Dickerson B, Sperling R. Hippocampal hyperactivation associated with cortical thinning in Alzheimer's disease signature regions in non-demented elderly adults. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 17680-8. PMID 22131428 DOI: 10.1523/Jneurosci.4740-11.2011 |
0.68 |
|
| 2011 |
Sperling R. Potential of functional MRI as a biomarker in early Alzheimer's disease. Neurobiology of Aging. 32: S37-43. PMID 22078171 DOI: 10.1016/J.Neurobiolaging.2011.09.009 |
0.448 |
|
| 2011 |
Reiman EM, McKhann GM, Albert MS, Sperling RA, Petersen RC, Blacker D. Alzheimer's disease: implications of the updated diagnostic and research criteria. The Journal of Clinical Psychiatry. 72: 1190-6. PMID 21951985 DOI: 10.4088/Jcp.10087Co1C |
0.47 |
|
| 2011 |
Salloway S, Sperling R, Keren R, Porsteinsson AP, van Dyck CH, Tariot PN, Gilman S, Arnold D, Abushakra S, Hernandez C, Crans G, Liang E, Quinn G, Bairu M, Pastrak A, et al. A phase 2 randomized trial of ELND005, scyllo-inositol, in mild to moderate Alzheimer disease. Neurology. 77: 1253-62. PMID 21917766 DOI: 10.1212/Wnl.0B013E3182309Fa5 |
0.361 |
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| 2011 |
Sabuncu MR, Desikan RS, Sepulcre J, Yeo BT, Liu H, Schmansky NJ, Reuter M, Weiner MW, Buckner RL, Sperling RA, Fischl B. The dynamics of cortical and hippocampal atrophy in Alzheimer disease. Archives of Neurology. 68: 1040-8. PMID 21825241 DOI: 10.1001/Archneurol.2011.167 |
0.422 |
|
| 2011 |
Jack CR, Barkhof F, Bernstein MA, Cantillon M, Cole PE, Decarli C, Dubois B, Duchesne S, Fox NC, Frisoni GB, Hampel H, Hill DL, Johnson K, Mangin JF, Scheltens P, ... ... Sperling R, et al. Steps to standardization and validation of hippocampal volumetry as a biomarker in clinical trials and diagnostic criterion for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 474-485.e4. PMID 21784356 DOI: 10.1016/J.Jalz.2011.04.007 |
0.407 |
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| 2011 |
Sperling RA, Jack CR, Black SE, Frosch MP, Greenberg SM, Hyman BT, Scheltens P, Carrillo MC, Thies W, Bednar MM, Black RS, Brashear HR, Grundman M, Siemers ER, Feldman HH, et al. Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: recommendations from the Alzheimer's Association Research Roundtable Workgroup. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 367-85. PMID 21784348 DOI: 10.1016/J.Jalz.2011.05.2351 |
0.34 |
|
| 2011 |
Marshall GA, Olson LE, Frey MT, Maye J, Becker JA, Rentz DM, Sperling RA, Johnson KA. Instrumental activities of daily living impairment is associated with increased amyloid burden. Dementia and Geriatric Cognitive Disorders. 31: 443-50. PMID 21778725 DOI: 10.1159/000329543 |
0.36 |
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| 2011 |
Ewers M, Sperling RA, Klunk WE, Weiner MW, Hampel H. Neuroimaging markers for the prediction and early diagnosis of Alzheimer's disease dementia. Trends in Neurosciences. 34: 430-42. PMID 21696834 DOI: 10.1016/J.Tins.2011.05.005 |
0.413 |
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| 2011 |
Rentz DM, Amariglio RE, Becker JA, Frey M, Olson LE, Frishe K, Carmasin J, Maye JE, Johnson KA, Sperling RA. Face-name associative memory performance is related to amyloid burden in normal elderly. Neuropsychologia. 49: 2776-83. PMID 21689670 DOI: 10.1016/J.Neuropsychologia.2011.06.006 |
0.35 |
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| 2011 |
Marshall GA, Rentz DM, Frey MT, Locascio JJ, Johnson KA, Sperling RA. Executive function and instrumental activities of daily living in mild cognitive impairment and Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 300-8. PMID 21575871 DOI: 10.1016/j.jalz.2010.04.005 |
0.372 |
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| 2011 |
Atri A, O'Brien JL, Sreenivasan A, Rastegar S, Salisbury S, DeLuca AN, O'Keefe KM, LaViolette PS, Rentz DM, Locascio JJ, Sperling RA. Test-retest reliability of memory task functional magnetic resonance imaging in Alzheimer disease clinical trials. Archives of Neurology. 68: 599-606. PMID 21555634 DOI: 10.1001/Archneurol.2011.94 |
0.308 |
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| 2011 |
Sperling RA, Aisen PS, Beckett LA, Bennett DA, Craft S, Fagan AM, Iwatsubo T, Jack CR, Kaye J, Montine TJ, Park DC, Reiman EM, Rowe CC, Siemers E, Stern Y, et al. Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 280-92. PMID 21514248 DOI: 10.1016/J.Jalz.2011.03.003 |
0.579 |
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| 2011 |
Jack CR, Albert MS, Knopman DS, McKhann GM, Sperling RA, Carrillo MC, Thies B, Phelps CH. Introduction to the recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 257-62. PMID 21514247 DOI: 10.1016/J.Jalz.2011.03.004 |
0.544 |
|
| 2011 |
Dickerson BC, Stoub TR, Shah RC, Sperling RA, Killiany RJ, Albert MS, Hyman BT, Blacker D, Detoledo-Morrell L. Alzheimer-signature MRI biomarker predicts AD dementia in cognitively normal adults. Neurology. 76: 1395-402. PMID 21490323 DOI: 10.1212/Wnl.0B013E3182166E96 |
0.797 |
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| 2011 |
Drzezga A, Becker JA, Van Dijk KR, Sreenivasan A, Talukdar T, Sullivan C, Schultz AP, Sepulcre J, Putcha D, Greve D, Johnson KA, Sperling RA. Neuronal dysfunction and disconnection of cortical hubs in non-demented subjects with elevated amyloid burden. Brain : a Journal of Neurology. 134: 1635-46. PMID 21490054 DOI: 10.1093/brain/awr066 |
0.479 |
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| 2011 |
Becker JA, Hedden T, Carmasin J, Maye J, Rentz DM, Putcha D, Fischl B, Greve DN, Marshall GA, Salloway S, Marks D, Buckner RL, Sperling RA, Johnson KA. Amyloid-β associated cortical thinning in clinically normal elderly. Annals of Neurology. 69: 1032-42. PMID 21437929 DOI: 10.1002/Ana.22333 |
0.416 |
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| 2011 |
Khachaturian ZS, Petersen RC, Snyder PJ, Khachaturian AS, Aisen P, de Leon M, Greenberg BD, Kukull W, Maruff P, Sperling RA, Stern Y, Touchon J, Vellas B, Andrieu S, Weiner MW, et al. Developing a global strategy to prevent Alzheimer's disease: Leon Thal Symposium 2010. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 127-32. PMID 21414553 DOI: 10.1016/J.Jalz.2011.02.005 |
0.463 |
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| 2011 |
Yang W, Lui RL, Gao JH, Chan TF, Yau ST, Sperling RA, Huang X. Independent component analysis-based classification of Alzheimer's disease MRI data. Journal of Alzheimer's Disease : Jad. 24: 775-83. PMID 21321398 DOI: 10.3233/Jad-2011-101371 |
0.364 |
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| 2011 |
Putcha D, O'Keefe K, LaViolette P, O'Brien J, Greve D, Rentz DM, Locascio J, Atri A, Sperling R. Reliability of functional magnetic resonance imaging associative encoding memory paradigms in non-demented elderly adults. Human Brain Mapping. 32: 2027-44. PMID 21259385 DOI: 10.1002/Hbm.21166 |
0.477 |
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| 2011 |
Bateman RJ, Aisen PS, De Strooper B, Fox NC, Lemere CA, Ringman JM, Salloway S, Sperling RA, Windisch M, Xiong C. Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease. Alzheimer's Research & Therapy. 3: 1. PMID 21211070 DOI: 10.1186/Alzrt59 |
0.526 |
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| 2011 |
Pihlajamäki M, O'Keefe K, O'Brien J, Blacker D, Sperling RA. Failure of repetition suppression and memory encoding in aging and Alzheimer's disease. Brain Imaging and Behavior. 5: 36-44. PMID 21161449 DOI: 10.1007/s11682-010-9110-3 |
0.384 |
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| 2011 |
Becker J, Gidicsin C, Maye J, Sperling R, Johnson K. P4-470: Characterizing biomarker dynamics along the Alzheimer's disease trajectory Alzheimer's & Dementia. 7: e74-e74. DOI: 10.1016/J.Jalz.2011.09.163 |
0.379 |
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| 2011 |
Sperling R, Salloway S, Arrighi M, Morris K, Lu Y, Liu E, Black R, Brashear RH, Grundman M. Revised estimates of incidence and risk factors for amyloid related imaging abnormalities (ARIA) in the phase 2 studies of bapineuzumab for mild-to-moderate Alzheimer's disease Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.09.134 |
0.384 |
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| 2011 |
Marshall G, Lorius N, Locascio J, Rentz D, Johnson K, Sperling R. Low CSF Abeta 1-42 is associated with worsening daily functioning in mild cognitive impairment and mild Alzheimer's disease Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.936 |
0.474 |
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| 2011 |
Wadsworth L, England R, Frishe K, Olson L, Johnson K, Sperling R, Rentz D. Paired associative learning is related to amyloid deposition in normal older individuals. Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.852 |
0.323 |
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| 2011 |
England R, Becker JA, Olson L, Frishe K, Frey M, Maye J, Johnson K, Sperling R, Rentz D. Comparison of multiple neuropsychological models to predict amyloid deposition Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.688 |
0.313 |
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| 2011 |
Maye J, Gidicsin C, Carmasin J, Becker JA, Blacker D, Rentz D, Sperling R, Johnson K. P1-382: Maternal history of dementia is associated with amyloid deposition and brain glucose hypometabolism in cognitively normal and mildly impaired elderly Alzheimer's & Dementia. 7: S234-S235. DOI: 10.1016/J.Jalz.2011.05.663 |
0.417 |
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| 2011 |
Rentz D, Betensky R, Becker A, England R, Maye J, Gidicsin C, Sperling R, Johnson K. P1-341: Amyloid deposition in non-demented elderly predicts longitudinal cognitive decline Alzheimer's & Dementia. 7: S221-S221. DOI: 10.1016/J.Jalz.2011.05.621 |
0.396 |
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| 2011 |
Wadsworth LP, Rentz D, Lorius N, Johnson K, Sperling R, Locascio J, Donvan N, Marshall G. Neuropsychiatric Symptoms are Associated with Current and Future Global Functional Impairment in Mild Cognitive Impairment Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.456 |
0.341 |
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| 2011 |
Sperling R. Can we detect Alzheimer's disease 10 years before dementia and why would we want to? Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.2319 |
0.427 |
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| 2011 |
McLaren D, Sperling R, Atri A. fMRI Context-dependent connectivity in Alzheimer's disease Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.2128 |
0.435 |
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| 2011 |
Porsteinsson A, Sperling R, Salloway S, Keren R, Dyck Cv, Tariot P, Arnold D, Crans G, Hernandez R, Liang E, Bairu M, Cedarbaum J, Pastrak A, Abushakra S. Imaging and cerebrospinal fluid biomarker results of a phase II dose-ranging study of ELND005 (Scyllo-inositol) in mild-to-moderate Alzheimer's disease Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.2010 |
0.345 |
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| 2011 |
Lorius N, Locascio J, Rentz D, Johnson K, Sperling R, Blacker D, Viswanathan A, Marshall G. Vascular risk factors are associated with cognitive decline in mild cognitive impairment Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1693 |
0.341 |
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| 2011 |
Salloway S, Porsteinsson A, Sperling R, Keren R, Dyck Cv, Tariot P, Gilman S, Crans G, Hernandez R, Quinn G, Bairu M, Cedarbaum J, Pastrak A, Abushakra S. Safety and efficacy results of a phase II randomized, placebo-controlled, dose-ranging study of elnd005 (scyllo-inositol) in mild-to-moderate Alzheimer's disease Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1371 |
0.32 |
|
| 2011 |
Quiroz Y, Sperling R, Lopera F, Fleisher A, Chen K, Tirado V, Munoz C, Langbaum J, Tariot P, Stern C, Reiman E. IC-P-066: Task-dependent fMRI abnormalities in young adults at genetic risk for early-onset Alzheimer's disease Alzheimer's & Dementia. 7: S34-S35. DOI: 10.1016/J.Jalz.2011.05.132 |
0.369 |
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| 2011 |
Vannini P, Hedden T, McLaren D, Maye J, Ward A, Sullivan C, Olson L, Becker J, Johnson K, Sperling R. P2-355: Increased amyloid deposition and parental history of Alzheimer's disease is related to altered default network activity during successful encoding in cognitively normal older adults Alzheimer's & Dementia. 7: S426-S427. DOI: 10.1016/J.Jalz.2011.05.1231 |
0.453 |
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| 2011 |
Dickerson B, Stoub T, Shah R, Sperling R, Killiany R, Albert M, Hyman B, Blacker D, DeToledo-Morrell L. IC-P-040: Alzheimer's signature MRI biomarker predicts likelihood of Alzheimer's dementia in cognitively normal adults Alzheimer's & Dementia. 7: S24-S25. DOI: 10.1016/J.Jalz.2011.05.109 |
0.768 |
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| 2011 |
Sperling R, Bronen R, Greenberg S, Sorensen AG, Salloway S, Gass A, Meadowcroft M, Berman R, Albright C, Coric V, Feldman H. Three cases of apparent Vasogenic Edema (VE) from a phase 2 clinical trial of the gamma secretase Inhibitor BMS-708163 in patients with mild-to-moderate AD Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1085 |
0.351 |
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| 2011 |
Feldman H, Coric V, Sperling R, Greenberg S, Bronen R, Sorensen AG, Salloway S, Pachai C, Kaplita S, Meadowcroft M, Albright C, Berman R. Cerebral microbleeds in a phase 2 clinical trial of mild-to-moderate Alzheimer's disease with the gamma secretase inhibitor BMS-708163 Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1080 |
0.382 |
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| 2011 |
Betensky R, Blacker D, Sperling R, Johnson K. P2-122: Time scales for time-to-event analyses of Alzheimer's studies Alzheimer's & Dementia. 7: S348-S348. DOI: 10.1016/J.Jalz.2011.05.1010 |
0.308 |
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| 2011 |
Quiroz Y, Stern C, Reiman E, Brickhouse M, Moreno S, Henao E, Sperling R, Lopera F, Dickerson B. Cortical signature of alzheimer's disease-related thinning in presymptomatic presenilin-1 mutation carriers Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.016 |
0.382 |
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| 2011 |
Pihlajamäki M, Sperling RA. Functional MRI in Alzheimer's Disease and Other Dementias The Handbook of Alzheimer's Disease and Other Dementias. 535-556. DOI: 10.1002/9781444344110.ch18 |
0.347 |
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| 2010 |
Desikan RS, Sabuncu MR, Schmansky NJ, Reuter M, Cabral HJ, Hess CP, Weiner MW, Biffi A, Anderson CD, Rosand J, Salat DH, Kemper TL, Dale AM, Sperling RA, Fischl B, et al. Selective disruption of the cerebral neocortex in Alzheimer's disease. Plos One. 5: e12853. PMID 20886094 DOI: 10.1371/Journal.Pone.0012853 |
0.433 |
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| 2010 |
Sperling R, Johnson K. Pro: Can biomarkers be gold standards in Alzheimer's disease? Alzheimer's Research & Therapy. 2: 17. PMID 20587006 DOI: 10.1186/alzrt41 |
0.394 |
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| 2010 |
O'Brien JL, O'Keefe KM, LaViolette PS, DeLuca AN, Blacker D, Dickerson BC, Sperling RA. Longitudinal fMRI in elderly reveals loss of hippocampal activation with clinical decline. Neurology. 74: 1969-76. PMID 20463288 DOI: 10.1212/Wnl.0B013E3181E3966E |
0.596 |
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| 2010 |
Rentz DM, Locascio JJ, Becker JA, Moran EK, Eng E, Buckner RL, Sperling RA, Johnson KA. Cognition, reserve, and amyloid deposition in normal aging. Annals of Neurology. 67: 353-64. PMID 20373347 DOI: 10.1002/ana.21904 |
0.359 |
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| 2010 |
Wang L, Laviolette P, O'Keefe K, Putcha D, Bakkour A, Van Dijk KR, Pihlajamäki M, Dickerson BC, Sperling RA. Intrinsic connectivity between the hippocampus and posteromedial cortex predicts memory performance in cognitively intact older individuals. Neuroimage. 51: 910-7. PMID 20188183 DOI: 10.1016/J.Neuroimage.2010.02.046 |
0.524 |
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| 2010 |
Wang L, Negreira A, LaViolette P, Bakkour A, Sperling RA, Dickerson BC. Intrinsic interhemispheric hippocampal functional connectivity predicts individual differences in memory performance ability. Hippocampus. 20: 345-51. PMID 20087893 DOI: 10.1002/Hipo.20771 |
0.476 |
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| 2010 |
Sperling RA, Dickerson BC, Pihlajamaki M, Vannini P, LaViolette PS, Vitolo OV, Hedden T, Becker JA, Rentz DM, Selkoe DJ, Johnson KA. Functional alterations in memory networks in early Alzheimer's disease. Neuromolecular Medicine. 12: 27-43. PMID 20069392 DOI: 10.1007/S12017-009-8109-7 |
0.696 |
|
| 2010 |
Pihlajamäki M, O' Keefe K, Bertram L, Tanzi RE, Dickerson BC, Blacker D, Albert MS, Sperling RA. Evidence of altered posteromedial cortical FMRI activity in subjects at risk for Alzheimer disease. Alzheimer Disease and Associated Disorders. 24: 28-36. PMID 19571734 DOI: 10.1097/Wad.0B013E3181A785C9 |
0.684 |
|
| 2010 |
Vitolo OV, Sperling RA. Functional MRI Studies in Ageing and Early Alzheimer's Disease Principles and Practice of Geriatric Psychiatry: Third Edition. 437-445. DOI: 10.1002/9780470669600.ch70 |
0.306 |
|
| 2009 |
Salloway S, Sperling R, Gilman S, Fox NC, Blennow K, Raskind M, Sabbagh M, Honig LS, Doody R, van Dyck CH, Mulnard R, Barakos J, Gregg KM, Liu E, Lieberburg I, et al. A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease. Neurology. 73: 2061-70. PMID 19923550 DOI: 10.1212/Wnl.0B013E3181C67808 |
0.395 |
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| 2009 |
Pihlajamäki M, Sperling RA. Functional MRI assessment of task-induced deactivation of the default mode network in Alzheimer's disease and at-risk older individuals. Behavioural Neurology. 21: 77-91. PMID 19847047 DOI: 10.3233/BEN-2009-0231 |
0.421 |
|
| 2009 |
Dickerson BC, Sperling RA. Large-scale functional brain network abnormalities in Alzheimer's disease: insights from functional neuroimaging. Behavioural Neurology. 21: 63-75. PMID 19847046 DOI: 10.3233/BEN-2009-0227 |
0.584 |
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| 2009 |
Hedden T, Van Dijk KR, Becker JA, Mehta A, Sperling RA, Johnson KA, Buckner RL. Disruption of functional connectivity in clinically normal older adults harboring amyloid burden. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12686-94. PMID 19812343 DOI: 10.1523/JNEUROSCI.3189-09.2009 |
0.342 |
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| 2009 |
Sperling RA, Laviolette PS, O'Keefe K, O'Brien J, Rentz DM, Pihlajamaki M, Marshall G, Hyman BT, Selkoe DJ, Hedden T, Buckner RL, Becker JA, Johnson KA. Amyloid deposition is associated with impaired default network function in older persons without dementia. Neuron. 63: 178-88. PMID 19640477 DOI: 10.1016/J.Neuron.2009.07.003 |
0.586 |
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| 2009 |
Carrillo MC, Blackwell A, Hampel H, Lindborg J, Sperling R, Schenk D, Sevigny JJ, Ferris S, Bennett DA, Craft S, Hsu T, Klunk W. Early risk assessment for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 5: 182-96. PMID 19328456 DOI: 10.1016/J.Jalz.2009.01.019 |
0.407 |
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| 2009 |
Chua EF, Schacter DL, Sperling RA. Neural basis for recognition confidence in younger and older adults. Psychology and Aging. 24: 139-53. PMID 19290745 DOI: 10.1037/A0014029 |
0.68 |
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| 2009 |
Buckner RL, Sepulcre J, Talukdar T, Krienen FM, Liu H, Hedden T, Andrews-Hanna JR, Sperling RA, Johnson KA. Cortical hubs revealed by intrinsic functional connectivity: mapping, assessment of stability, and relation to Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1860-73. PMID 19211893 DOI: 10.1523/Jneurosci.5062-08.2009 |
0.333 |
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| 2009 |
Chua EF, Schacter DL, Sperling RA. Neural correlates of metamemory: a comparison of feeling-of-knowing and retrospective confidence judgments. Journal of Cognitive Neuroscience. 21: 1751-65. PMID 18823230 DOI: 10.1162/Jocn.2009.21123 |
0.69 |
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| 2009 |
Dickerson BC, Bakkour A, Salat DH, Feczko E, Pacheco J, Greve DN, Grodstein F, Wright CI, Blacker D, Rosas HD, Sperling RA, Atri A, Growdon JH, Hyman BT, Morris JC, et al. The cortical signature of Alzheimer's disease: regionally specific cortical thinning relates to symptom severity in very mild to mild AD dementia and is detectable in asymptomatic amyloid-positive individuals. Cerebral Cortex (New York, N.Y. : 1991). 19: 497-510. PMID 18632739 DOI: 10.1093/Cercor/Bhn113 |
0.576 |
|
| 2009 |
Wang L, laViolette P, O'Keefe K, Putcha D, Hamdi I, Vannini P, Dijk KV, Bakkour A, Sreenivasan A, Atri A, Dickerson B, Sperling R. Intrinsic Connectivity of the Hippocampus and Precuneus/Posterior Cingulate Cortex Predicts Memory Performance in Cognitively Intact Older Individuals Neuroimage. 47. DOI: 10.1016/S1053-8119(09)71494-6 |
0.574 |
|
| 2009 |
Atri A, Locascio J, Sperling R. Optimizing FMRI test-retest reliability and power estimates for Alzheimer's disease early-phase studies: Modeling decline and leveraging network properties Alzheimers & Dementia. 5: 373. DOI: 10.1016/J.Jalz.2009.04.1175 |
0.334 |
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| 2009 |
Raskind M, Liang E, Sperling R, Boxer A, Ross J, Brody M, Garzone P, Raje S, Black R, Grundman M. Pharmacokinetics and pharmacodynamics of bapineuzumab following multiple intravenous infusions in patients with mild-to-moderate Alzheimer's disease Alzheimers & Dementia. 5. DOI: 10.1016/J.Jalz.2009.04.1019 |
0.394 |
|
| 2009 |
Sperling R, Johnson K, Pontecorvo MJ, Safirstein B, Farmer M, Holub R, Korn R, Spicer K, Doraiswamy M, Reiman EM, Joshi A, Saha K, Flitter M, Clark CM, Skovronsky DM. P1-084: PET imaging of β-amyloid with florpiramine F18 (18F-AV-45): Preliminary results from a phase II study of cognitively normal elderly subjects, individuals with mild cognitive impairment, and patients with a clinical diagnosis of Alzheimer's disease Alzheimer's & Dementia. 5: P197-P197. DOI: 10.1016/J.Jalz.2009.04.088 |
0.419 |
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| 2008 |
Pihlajamäki M, DePeau KM, Blacker D, Sperling RA. Impaired medial temporal repetition suppression is related to failure of parietal deactivation in Alzheimer disease. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 16: 283-92. PMID 18378553 DOI: 10.1097/JGP.0b013e318162a0a9 |
0.381 |
|
| 2008 |
Miller SL, Celone K, DePeau K, Diamond E, Dickerson BC, Rentz D, Pihlajamäki M, Sperling RA. Age-related memory impairment associated with loss of parietal deactivation but preserved hippocampal activation. Proceedings of the National Academy of Sciences of the United States of America. 105: 2181-6. PMID 18238903 DOI: 10.1073/Pnas.0706818105 |
0.805 |
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| 2008 |
Dickerson BC, Sperling RA. Functional abnormalities of the medial temporal lobe memory system in mild cognitive impairment and Alzheimer's disease: insights from functional MRI studies. Neuropsychologia. 46: 1624-35. PMID 18206188 DOI: 10.1016/j.neuropsychologia.2007.11.030 |
0.578 |
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| 2008 |
Miller SL, Fenstermacher E, Bates J, Blacker D, Sperling RA, Dickerson BC. Hippocampal activation in adults with mild cognitive impairment predicts subsequent cognitive decline. Journal of Neurology, Neurosurgery, and Psychiatry. 79: 630-5. PMID 17846109 DOI: 10.1136/jnnp.2007.124149 |
0.561 |
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| 2008 |
Pihlajamäki M, Sperling RA. fMRI: Use in early Alzheimer's disease and in clinical trials Future Neurology. 3: 409-421. DOI: 10.2217/14796708.3.4.409 |
0.433 |
|
| 2008 |
Sperling R, O'Brien J, O'Keefe K, DeLuca A, LaViolette P, Pihlajamaki M, Johnson K, Blacker D, Dickerson B. P1-295: Longitudinal functional MRI demonstrates loss of hippocampal activation associated with clinical decline in nondemented older subjects Alzheimer's & Dementia. 4: T305-T305. DOI: 10.1016/J.Jalz.2008.05.885 |
0.544 |
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| 2008 |
Becker JA, Carmasin J, Fischl B, Greve D, DeLuca A, LaViolette P, O'Brien J, O'Keefe K, Fischman A, Rentz D, Sperling R, Johnson K. P1-221: Amyloid deposition related to cortical thinning Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.810 |
0.342 |
|
| 2008 |
Sperling R, O'Brien J, O'Keefe K, DeLuca A, LaViolette P, Pihlajamaki M, Johnson K, Blacker D, Dickerson B. IC-P2-139: Longitudinal fMRI demonstrates loss of hippocampal function associated with clinical decline in non-demented older subjects Alzheimer's & Dementia. 4: T62-T62. DOI: 10.1016/J.Jalz.2008.05.2593 |
0.598 |
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| 2008 |
Sperling R. S1-01-06: Functional magnetic resonance imaging in early Alzheimer's disease Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.188 |
0.359 |
|
| 2007 |
Dickerson BC, Sperling RA, Hyman BT, Albert MS, Blacker D. Clinical prediction of Alzheimer disease dementia across the spectrum of mild cognitive impairment. Archives of General Psychiatry. 64: 1443-50. PMID 18056553 DOI: 10.1001/Archpsyc.64.12.1443 |
0.669 |
|
| 2007 |
Diamond EL, Miller S, Dickerson BC, Atri A, DePeau K, Fenstermacher E, Pihlajamäki M, Celone K, Salisbury S, Gregas M, Rentz D, Sperling RA. Relationship of fMRI activation to clinical trial memory measures in Alzheimer disease. Neurology. 69: 1331-41. PMID 17893294 DOI: 10.1212/01.Wnl.0000277292.37292.69 |
0.833 |
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| 2007 |
Rentz DM, Huh TJ, Sardinha LM, Moran EK, Becker JA, Daffner KR, Sperling RA, Johnson KA. Intelligence quotient-adjusted memory impairment is associated with abnormal single photon emission computed tomography perfusion. Journal of the International Neuropsychological Society : Jins. 13: 821-31. PMID 17697413 DOI: 10.1017/S1355617707071056 |
0.655 |
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| 2007 |
Dickerson BC, Miller SL, Greve DN, Dale AM, Albert MS, Schacter DL, Sperling RA. Prefrontal-hippocampal-fusiform activity during encoding predicts intraindividual differences in free recall ability: an event-related functional-anatomic MRI study. Hippocampus. 17: 1060-70. PMID 17604356 DOI: 10.1002/Hipo.20338 |
0.586 |
|
| 2007 |
Chua EF, Schacter DL, Rand-Giovannetti E, Sperling RA. Evidence for a specific role of the anterior hippocampal region in successful associative encoding. Hippocampus. 17: 1071-80. PMID 17604351 DOI: 10.1002/Hipo.20340 |
0.688 |
|
| 2007 |
Sperling R. Functional MRI studies of associative encoding in normal aging, mild cognitive impairment, and Alzheimer's disease. Annals of the New York Academy of Sciences. 1097: 146-55. PMID 17413017 DOI: 10.1196/Annals.1379.009 |
0.559 |
|
| 2007 |
Chappell AS, Gonzales C, Williams J, Witte MM, Mohs RC, Sperling R. AMPA potentiator treatment of cognitive deficits in Alzheimer disease. Neurology. 68: 1008-12. PMID 17389305 DOI: 10.1212/01.Wnl.0000260240.46070.7C |
0.363 |
|
| 2007 |
Sperling R, LaViolette P, White E, Becker JA, Moran E, Gregas M, Klunk W, Mathis C, Price J, Fischman A, Selkoe D, Rentz D, Johnson K. O1-05-01: Cortical amyloid deposition related to failure of hippocampal activation Alzheimers & Dementia. 3. DOI: 10.1016/J.Jalz.2007.04.068 |
0.49 |
|
| 2006 |
Celone KA, Calhoun VD, Dickerson BC, Atri A, Chua EF, Miller SL, DePeau K, Rentz DM, Selkoe DJ, Blacker D, Albert MS, Sperling RA. Alterations in memory networks in mild cognitive impairment and Alzheimer's disease: an independent component analysis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 10222-31. PMID 17021177 DOI: 10.1523/Jneurosci.2250-06.2006 |
0.837 |
|
| 2006 |
Rentz DM, Sardinha LM, Huh TJ, Searl MM, Daffner KR, Sperling RA. IQ-based norms for highly intelligent adults. The Clinical Neuropsychologist. 20: 637-48. PMID 16980251 DOI: 10.1080/13854040500477498 |
0.597 |
|
| 2006 |
Chua EF, Schacter DL, Rand-Giovannetti E, Sperling RA. Understanding metamemory: neural correlates of the cognitive process and subjective level of confidence in recognition memory. Neuroimage. 29: 1150-60. PMID 16303318 DOI: 10.1016/J.Neuroimage.2005.09.058 |
0.696 |
|
| 2006 |
Rand-Giovannetti E, Chua EF, Driscoll AE, Schacter DL, Albert MS, Sperling RA. Hippocampal and neocortical activation during repetitive encoding in older persons. Neurobiology of Aging. 27: 173-82. PMID 16298252 DOI: 10.1016/J.Neurobiolaging.2004.12.013 |
0.751 |
|
| 2006 |
Papp KV, Rentz DM, Maruff P, Sun C, Raman R, Donohue MC, Schembri A, Stark CE, Yassa MA, Holdridge KC, Wessels AM, Yaari R, Aisen PS, Sperling RA. P4-341: THE COMPUTERIZED COGNITIVE COMPOSITE (C3) AND AMYLOID STATUS AMONG NORMAL OLDER ADULTS Alzheimer's & Dementia. 14: P1597-P1598. DOI: 10.1016/J.Jalz.2018.07.164 |
0.453 |
|
| 2006 |
Johnson KA, Schultz AP, Raman R, Donohue MC, Sun C, Jacobs HI, Marek K, Seibyl J, Mintun MA, Shcherbinin S, Pontecorvo MJ, Mormino BC, Rowe CC, van Dyck CH, Salloway S, ... ... Sperling RA, et al. P4-321: TAU PET IN A4: PRELIMINARY REPORT Alzheimer's & Dementia. 14: P1583-P1584. DOI: 10.1016/J.Jalz.2018.07.144 |
0.369 |
|
| 2006 |
Quiroz YT, Sperling RA, Lopera F, Baena A, Alvarez S, Guzman-Velez E, Pardilla-Delgado E, Arboleda-Velasquez J, Gatchel JR, Fuller J, Artola A, Schultz AP, Chen K, Tariot PN, Reiman EM, et al. P4-299: TAU ACCUMULATION IN THE ENTORHINAL CORTEX AND PRECUNEUS IS ASSOCIATED WITH CORTICAL AMYLOID-BETA BURDEN, AGE AND WORSE MEMORY PERFORMANCE IN PRECLINICAL AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P1567-P1567. DOI: 10.1016/J.Jalz.2018.07.121 |
0.362 |
|
| 2006 |
Lim Y, Maruff P, Masters CL, Sperling RA, Johnson KA, Mormino BC. P4-118: AV1451 TAU PET, BUT NOT CSF TAU, IS RELATED TO MEMORY DECLINE IN PRECLINICAL AND PRODROMAL ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P1484-P1484. DOI: 10.1016/j.jalz.2018.06.2522 |
0.36 |
|
| 2006 |
Donohue MC, Raman R, Sun C, Langford O, Johnson KA, Aisen PS, Sperling RA. O1-02-05: PREDICTING AMYLOID BURDEN IN SCREENING FOR PRECLINICAL AD PREVENTION TRIALS Alzheimer's & Dementia. 14: P217-P218. DOI: 10.1016/J.Jalz.2018.06.2340 |
0.46 |
|
| 2006 |
Sanchez JS, Sperling RA, Lopera F, Augustinack J, Becker A, Jacobs HI, Jin D, Katz S, Luner E, Moody K, Price JC, Guzman-Velez E, Baena A, Pardilla-Delgado E, Chen K, et al. IC-P-215: TAU ACCUMULATION IN RHINAL CORTEX IS ASSOCIATED WITH MEMORY PERFORMANCE IN NON-DEMENTED YOUNG ADULTS WITH AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P176-P177. DOI: 10.1016/J.Jalz.2018.06.2282 |
0.342 |
|
| 2006 |
Hanseeuw BJ, Lopera F, Sperling RA, Norton D, Guzman-Velez E, Baena A, Schultz AP, Gatchel JR, Chen K, Reiman EM, Johnson KA, Quiroz YT. IC-P-140: TAU ACCUMULATION AND MEMORY DECLINE ARE MORE CLOSELY RELATED TO STRIATAL THAN CORTICAL AMYLOIDOSIS IN INDIVIDUALS WITH EARLY-ONSET AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P117-P117. DOI: 10.1016/J.Jalz.2018.06.2206 |
0.351 |
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| 2006 |
Jacobs HI, Lopera F, Sperling RA, Norton D, Guzman-Velez E, Baena A, Pardilla-Delgado E, Gatchel JR, Chen K, Reiman EM, Johnson KA, Quiroz YT. P2-461: ENTORHINAL TAU PATHOLOGY IS ASSOCIATED WITH WHITE MATTER ABNORMALITIES IN UNCINATE FASCICULUS IN PRECLINICAL AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P897-P898. DOI: 10.1016/J.Jalz.2018.06.1154 |
0.305 |
|
| 2006 |
Sanchez JS, Sperling RA, Lopera F, Augustinack J, Becker A, Jacobs HI, Jin D, Katz S, Luner E, Moody K, Price JC, Guzman-Velez E, Baena A, Pardilla-Delgado E, Chen K, et al. P2-452: TAU ACCUMULATION IN RHINAL CORTEX IS ASSOCIATED WITH MEMORY PERFORMANCE IN NONDEMENTED YOUNG ADULTS WITH AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P892-P892. DOI: 10.1016/j.jalz.2018.06.1145 |
0.358 |
|
| 2006 |
Dickerson BC, Hevelone N, Sperling RA, Albert MS, Blacker D. P2-073: Prediction of cognitive decline among very mild MCI cases Alzheimer's & Dementia. 2: S254-S254. DOI: 10.1016/J.Jalz.2006.05.910 |
0.581 |
|
| 2006 |
Pihlajamaki M, Miller SM, DePeau KM, Celone KA, Bertram L, Tanzi RE, Dickerson BC, Albert MS, Blacker D, Sperling RA. O4-01-02: The effect of APOE-4
on fMRI deactivation in older controls, MCI subjects and AD patients Alzheimer's & Dementia. 2: S74-S75. DOI: 10.1016/J.Jalz.2006.05.292 |
0.804 |
|
| 2006 |
Sperling R, Depeau K, Miller S, Chua E, Rentz D, Dickerson B, Atri A, Selkoe D, Johnson K, Calhoun V, Albert M, Celone K. Ic-101-05 Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.2344 |
0.738 |
|
| 2006 |
DePeau KM, Pihlajamaki M, Diamond EL, Miller SM, Chua EF, Dickerson BC, Albert MS, Blacker D, Sperling RA. IC-P-086: Failure of hippocampal habituation in mild cognitive impairment and Alzheimer's disease Alzheimer's & Dementia. 2: S687-S688. DOI: 10.1016/J.Jalz.2006.05.2291 |
0.76 |
|
| 2006 |
Pihlajamaki M, Miller SM, DePeau KM, Celone KA, Bertram L, Tanzi RE, Dickerson BC, Albert MS, Blacker D, Sperling RA. IC-P-071: The effect of APOE-4
on fMRI deactivation in older controls, MCI subjects and AD patients Alzheimer's & Dementia. 2: S681-S681. DOI: 10.1016/J.Jalz.2006.05.2276 |
0.806 |
|
| 2006 |
Johnson KA, Pollen D, Rentz D, Moran E, Becker JA, Moonis M, Swearer J, Hyman B, Selkoe D, Sperling R, DeKosky S, Matthis C, Klunk W, Fischman A. IC-103-03: Amyloid deposition in presymptomatic familial Alzheimer's disease Alzheimer's & Dementia. 2: S653-S653. DOI: 10.1016/J.Jalz.2006.05.2198 |
0.539 |
|
| 2006 |
DePeau KM, Pihlajamaki M, Diamond EL, Miller SM, Chua EF, Dickerson BC, Albert MS, Blacker D, Sperling RA. P2-381: Failure of hippocampal habituation in mild cognitive impairment and Alzheimer's disease Alzheimer's & Dementia. 2: S357-S358. DOI: 10.1016/j.jalz.2006.05.1221 |
0.34 |
|
| 2006 |
Miller SL, Bates J, Blacker D, Sperling R, Dickerson BC. IC-P-081: Hippocampal activation in MCI predicts subsequent cognitive decline Alzheimer's & Dementia. 2: S685-S686. DOI: 10.1016/J.Jalz.2006.05.1202 |
0.547 |
|
| 2006 |
Sperling R, Depeau K, Miller S, Chua E, Dorene R, Dickerson B, Atri A, Selkoe D, Albert M, Calhoun V, Celone K. P2-302: FMRI alterations medial temporal and neocortical networks in MCI and AD Alzheimer's & Dementia. 2: S328-S329. DOI: 10.1016/J.Jalz.2006.05.1142 |
0.8 |
|
| 2006 |
Johnson KA, Pollen D, Rentz D, Moran E, Becker JA, Moonis M, Swearer J, Hyman B, Selkoe D, Sperling R, DeKosky S, Matthis C, Klunk W, Fischman A. P2-268: Amyloid deposition in presymptomatic familial Alzheimer's disease Alzheimer's & Dementia. 2: S317-S317. DOI: 10.1016/J.Jalz.2006.05.1107 |
0.548 |
|
| 2006 |
Dickerson BC, Murthi S, Fenstermacher E, Sperling RA, Blacker D, Csernansky JG, Wang L. P2-257: Hippocampal shape deformities and functional hyperactivation in MCI Alzheimer's & Dementia. 2: S312-S312. DOI: 10.1016/j.jalz.2006.05.1096 |
0.431 |
|
| 2006 |
Dickerson BC, Murthi S, Fenstermacher E, Sperling RA, Blacker D, Csernansky JG, Wang L. IC-P-077: Hippocampal shape deformities and functional hyperactivation in MCI Alzheimer's & Dementia. 2: S683-S684. DOI: 10.1016/J.Jalz.2006.05.1096 |
0.423 |
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